Tri-training利用无标签数据进行分类可有效提高分类器的泛化能力,但其易将无标签数据误标,从而形成训练噪声。提出一种基于密度峰值聚类的Tri-training(Tri-training with density peaks clustering,DPC-TT)算法。密度峰值聚类通过类...Tri-training利用无标签数据进行分类可有效提高分类器的泛化能力,但其易将无标签数据误标,从而形成训练噪声。提出一种基于密度峰值聚类的Tri-training(Tri-training with density peaks clustering,DPC-TT)算法。密度峰值聚类通过类簇中心和局部密度可选出数据空间结构表现较好的样本。DPC-TT算法采用密度峰值聚类算法获取训练数据的类簇中心和样本的局部密度,对类簇中心的截断距离范围内的样本认定为空间结构表现较好,标记为核心数据,使用核心数据更新分类器,可降低迭代过程中的训练噪声,进而提高分类器的性能。实验结果表明:相比于标准Tritraining算法及其改进算法,DPC-TT算法具有更好的分类性能。展开更多
Background: Isolated tricuspid valve disease remains a controversial indication for surgical intervention. Many patients referred for surgery already have a poor clinical condition and an advanced New York Heart Assoc...Background: Isolated tricuspid valve disease remains a controversial indication for surgical intervention. Many patients referred for surgery already have a poor clinical condition and an advanced New York Heart Association functional class. There is no consensus on the optimal surgical technique for this condition, including on whether to perform the procedure on a beating or an arrested heart and whether to perform valve repair or replacement. Methods: We analyzed four case series between 2015 and 2022 in which patients with secondary tricuspid regurgitation (TR) underwent valve repair on a beating heart and right atrial plication for a dilated right atrium. The TRI-SCORE was calculated for each patient. Results: All patients experienced a favorable postoperative course with significant improvements in heart failure symptoms. TR was markedly reduced;however, in one patient with concomitant mitral regurgitation (MR) and a high TRI-SCORE, MR worsened postoperatively. This patient later died from unknown causes due to multiple comorbidities in the late phase. Conclusions: Tricuspid valve repair on a beating heart was effective for improving the cardiac function, and the TRI-SCORE proved useful as a preoperative risk assessment tool. The underlying mechanism by which TR exacerbates MR requires further investigation.展开更多
AIM:To compare the postoperative binocular visual performance with an iTrace analyzer following femtosecond laser-assisted cataract surgery(FLACS)combined with bilateral implantation of two different types of diffract...AIM:To compare the postoperative binocular visual performance with an iTrace analyzer following femtosecond laser-assisted cataract surgery(FLACS)combined with bilateral implantation of two different types of diffractive trifocal intraocular lenses(IOL).METHODS:During this retrospective observational study,patients who received bilateral FLACS combined with implantation of two different types of diffractive trifocal IOLs were evaluated.According to the IOLs’different types and design,the patients were divided into AT LISA tri839MP group(tri839 group)and AcrySof PanOptix TFNT00 group(TFNT group).Study parameters included preoperative and postoperative uncorrected distance visual acuity(UDVA)at 5 m,uncorrected near visual acuity(UNVA)at 30 cm and 40 cm,uncorrected intermediate visual acuity(UIVA)at 60 cm and 80 cm,postoperative refractive status,objective visual qualities and total high order aberrations(HOAs)postoperatively.The postoperative complications were also recorded.RESULTS:Totally 56 eyes of 28 patients(tri839 group,n=26;TFNT group,n=30)were included.Preoperative baseline characteristics between groups were not statistically significantly different.UDVA was not significantly different between groups except for 1wk follow-up due to the postoperative corneal edema.TFNT group showed statistically significant better UNIA at 60 cm than tri839 group at the 1wk(0.05±0.19 vs 0.15±0.10 logMAR,P=0.013),1mo(0.05±0.12 vs 0.15±0.09 logMAR,P=0.001)and 3mo(0.04±0.12 vs 0.15±0.11 logMAR,P=0.001)follow-up,while tri839 group showed statistically significant better UNIA at 80 cm than TFNT group at the 1d(0.14±0.15 vs 0.20±0.14 logMAR,P=0.041)and 1mo(0.09±0.07 vs 0.14±0.10 logMAR,P=0.042)follow-up.Postoperative refractive status showed stable at every visit.Modulated transfer function(MTF)values and strehl ratio(SR)values were improved and HOAs were lower significantly after surgery.CONCLUSION:FLACS with bilateral implantations of both tri839 and TFNT00 can achieve satisfactory natural whole-course vision,high postoperative refractive stability and good visual quality but without significantly difference.iTrace aberration instrument can accurately evaluate the visual quality under different status.展开更多
On December 6,CIIS,Japan Institute of International Affairs(JIIA)and Institute of Foreign Affairs and National Security,Korea National Diplomatic Academy(IFANS KNDA)co-hosted the 16th China-Japan-ROK Trilateral Cooper...On December 6,CIIS,Japan Institute of International Affairs(JIIA)and Institute of Foreign Affairs and National Security,Korea National Diplomatic Academy(IFANS KNDA)co-hosted the 16th China-Japan-ROK Trilateral Cooperation Forum.CIIS President Chen Bo,JIIA Director General Yoshida Tomoyuki and Senior Executive Director Lee Moonhee of IFANS,KNDA delivered opening remarks.Experts and scholars discussed the global and regional security situation,prospects of Asia-Pacific economic cooperation and trilateral cooperation between China,Japan and the ROK.展开更多
Background: Accurate determination of gestational age has become important for deciding the appropriate time for termination of the pregnancy as well as to monitor the fetal growth during the entire period of pregnanc...Background: Accurate determination of gestational age has become important for deciding the appropriate time for termination of the pregnancy as well as to monitor the fetal growth during the entire period of pregnancy. Objective: The aim of the study was to assess whether the trans-cerebellar diameter, placental thickness or combining both of them is more accurate for assessment of gestational age in the 3<sup>rd</sup> trimester of pregnancy. Patients and Methods: This is a cross sectional study conducted at outpatient Clinic and Obstetric ward, Ain Shams University Maternity Hospital, over a period of six months from March 2019 to September 2019. One hundred pregnant women were recruited according to inclusion criteria either from outpatient clinic or were admitted in obstetric ward Ain Shams Maternity Hospital to find out the most accurate fetal biometric measurement in the third trimester either trans-cerebellar diameter placental thickness or both compared to reliable LMP (last menstrual period) dates confirmed by crown rump length (CRL) in the first trimester. Results: Trans-cerebellar diameter mean ± SD was 46.0 ± 3.5 with range 38.2 - 51.7. The mean of placental thickness was 39.6 ± 7.1 with range 22.8 - 54.3. Placental thickness had highest determination (0.813) for last menstrual period followed by trans-cerebellar diameter (0.802). Combining trans-cerebellar diameter and placental thickness increased determination (0.902) for last menstrual period. Conclusion: Combined use of trans-cerebellar diameter and placental thickness in the third trimester of pregnancy is a reliable indicator for gestational age in women whose last menstrual period is unreliable or unknown, but placental thickness had higher accuracy than trans-cerebellar diameter.展开更多
The problem with earth constructions is their low resistance to water. Step by step, the water degrades the exterior facings of the structures and ends up creating zones of weakness through the structures, making them...The problem with earth constructions is their low resistance to water. Step by step, the water degrades the exterior facings of the structures and ends up creating zones of weakness through the structures, making them collapse and creating enormous socio-economic problems, especially in rural areas. The solutions proposed to date, like the use of straw, cow dung, boiled skins, banana leaves, tar, cement soil, have shown their limits. Generally, the poor adhesion between the protected material and the protective layer means that the latter always ends up peeling off. This work, which is inspired by the traditional practice where plant tannins are used to brush the earthen walls to waterproof them, proposes a tri-layer coating composed of soil, powder and hydrolysable tannins extracted from the stem bark of Bridelia. This work focuses on the geotechnical characterization of the soil, the extraction of hydrolysable tannin, the manufacture of the micro-coating, the resistance tests carried out on the micro-coating, the technique of implementation and the test of evaluation of the performance of the tri-layer coating. The results obtained show that not only does the tri-layer coating adhere perfectly to the layer to protect, but it also waterproofs it and protects it against shocks.展开更多
Resorbable bioceramics are attractive for medical applications such as bone substitution. Biochemical analysis on cells cultured on these biomaterials is vital to predict the impact of the materials in vivo and RNA ex...Resorbable bioceramics are attractive for medical applications such as bone substitution. Biochemical analysis on cells cultured on these biomaterials is vital to predict the impact of the materials in vivo and RNA extraction is an essential step in gene expression study using RT-qPCR. In this study, we describe simple modifications to the TRIzol? RNA extraction protocol widely used in biology and these allow high-yield extraction of RNA from cells on resorbable calcium phosphates. Without the modifications, RNA is trapped in the co-precipitated calcium compounds, rendering TRIzol? extraction method infeasible. Among the modifications, the use of extra TRIzol? to dilute the lysate before the RNA precipitation step is critical for extraction of RNA from porous ?-tricalcium phosphate (?-TCP) discs. We also investigate the rationale behind the undesirable precipitation so as to provide clues about the modifications required for other resorbable materials with high application potential in bone tissue engineering.展开更多
文摘Tri-training利用无标签数据进行分类可有效提高分类器的泛化能力,但其易将无标签数据误标,从而形成训练噪声。提出一种基于密度峰值聚类的Tri-training(Tri-training with density peaks clustering,DPC-TT)算法。密度峰值聚类通过类簇中心和局部密度可选出数据空间结构表现较好的样本。DPC-TT算法采用密度峰值聚类算法获取训练数据的类簇中心和样本的局部密度,对类簇中心的截断距离范围内的样本认定为空间结构表现较好,标记为核心数据,使用核心数据更新分类器,可降低迭代过程中的训练噪声,进而提高分类器的性能。实验结果表明:相比于标准Tritraining算法及其改进算法,DPC-TT算法具有更好的分类性能。
文摘Background: Isolated tricuspid valve disease remains a controversial indication for surgical intervention. Many patients referred for surgery already have a poor clinical condition and an advanced New York Heart Association functional class. There is no consensus on the optimal surgical technique for this condition, including on whether to perform the procedure on a beating or an arrested heart and whether to perform valve repair or replacement. Methods: We analyzed four case series between 2015 and 2022 in which patients with secondary tricuspid regurgitation (TR) underwent valve repair on a beating heart and right atrial plication for a dilated right atrium. The TRI-SCORE was calculated for each patient. Results: All patients experienced a favorable postoperative course with significant improvements in heart failure symptoms. TR was markedly reduced;however, in one patient with concomitant mitral regurgitation (MR) and a high TRI-SCORE, MR worsened postoperatively. This patient later died from unknown causes due to multiple comorbidities in the late phase. Conclusions: Tricuspid valve repair on a beating heart was effective for improving the cardiac function, and the TRI-SCORE proved useful as a preoperative risk assessment tool. The underlying mechanism by which TR exacerbates MR requires further investigation.
基金Supported by Medical Science and Technology Research Foundation Project of Guangdong Province(No.C2021087)The Scientific Research Foundation Project of Guangzhou Aier Eye Hospital,Jinan University(No.GA2023004).
文摘AIM:To compare the postoperative binocular visual performance with an iTrace analyzer following femtosecond laser-assisted cataract surgery(FLACS)combined with bilateral implantation of two different types of diffractive trifocal intraocular lenses(IOL).METHODS:During this retrospective observational study,patients who received bilateral FLACS combined with implantation of two different types of diffractive trifocal IOLs were evaluated.According to the IOLs’different types and design,the patients were divided into AT LISA tri839MP group(tri839 group)and AcrySof PanOptix TFNT00 group(TFNT group).Study parameters included preoperative and postoperative uncorrected distance visual acuity(UDVA)at 5 m,uncorrected near visual acuity(UNVA)at 30 cm and 40 cm,uncorrected intermediate visual acuity(UIVA)at 60 cm and 80 cm,postoperative refractive status,objective visual qualities and total high order aberrations(HOAs)postoperatively.The postoperative complications were also recorded.RESULTS:Totally 56 eyes of 28 patients(tri839 group,n=26;TFNT group,n=30)were included.Preoperative baseline characteristics between groups were not statistically significantly different.UDVA was not significantly different between groups except for 1wk follow-up due to the postoperative corneal edema.TFNT group showed statistically significant better UNIA at 60 cm than tri839 group at the 1wk(0.05±0.19 vs 0.15±0.10 logMAR,P=0.013),1mo(0.05±0.12 vs 0.15±0.09 logMAR,P=0.001)and 3mo(0.04±0.12 vs 0.15±0.11 logMAR,P=0.001)follow-up,while tri839 group showed statistically significant better UNIA at 80 cm than TFNT group at the 1d(0.14±0.15 vs 0.20±0.14 logMAR,P=0.041)and 1mo(0.09±0.07 vs 0.14±0.10 logMAR,P=0.042)follow-up.Postoperative refractive status showed stable at every visit.Modulated transfer function(MTF)values and strehl ratio(SR)values were improved and HOAs were lower significantly after surgery.CONCLUSION:FLACS with bilateral implantations of both tri839 and TFNT00 can achieve satisfactory natural whole-course vision,high postoperative refractive stability and good visual quality but without significantly difference.iTrace aberration instrument can accurately evaluate the visual quality under different status.
文摘On December 6,CIIS,Japan Institute of International Affairs(JIIA)and Institute of Foreign Affairs and National Security,Korea National Diplomatic Academy(IFANS KNDA)co-hosted the 16th China-Japan-ROK Trilateral Cooperation Forum.CIIS President Chen Bo,JIIA Director General Yoshida Tomoyuki and Senior Executive Director Lee Moonhee of IFANS,KNDA delivered opening remarks.Experts and scholars discussed the global and regional security situation,prospects of Asia-Pacific economic cooperation and trilateral cooperation between China,Japan and the ROK.
文摘Background: Accurate determination of gestational age has become important for deciding the appropriate time for termination of the pregnancy as well as to monitor the fetal growth during the entire period of pregnancy. Objective: The aim of the study was to assess whether the trans-cerebellar diameter, placental thickness or combining both of them is more accurate for assessment of gestational age in the 3<sup>rd</sup> trimester of pregnancy. Patients and Methods: This is a cross sectional study conducted at outpatient Clinic and Obstetric ward, Ain Shams University Maternity Hospital, over a period of six months from March 2019 to September 2019. One hundred pregnant women were recruited according to inclusion criteria either from outpatient clinic or were admitted in obstetric ward Ain Shams Maternity Hospital to find out the most accurate fetal biometric measurement in the third trimester either trans-cerebellar diameter placental thickness or both compared to reliable LMP (last menstrual period) dates confirmed by crown rump length (CRL) in the first trimester. Results: Trans-cerebellar diameter mean ± SD was 46.0 ± 3.5 with range 38.2 - 51.7. The mean of placental thickness was 39.6 ± 7.1 with range 22.8 - 54.3. Placental thickness had highest determination (0.813) for last menstrual period followed by trans-cerebellar diameter (0.802). Combining trans-cerebellar diameter and placental thickness increased determination (0.902) for last menstrual period. Conclusion: Combined use of trans-cerebellar diameter and placental thickness in the third trimester of pregnancy is a reliable indicator for gestational age in women whose last menstrual period is unreliable or unknown, but placental thickness had higher accuracy than trans-cerebellar diameter.
文摘The problem with earth constructions is their low resistance to water. Step by step, the water degrades the exterior facings of the structures and ends up creating zones of weakness through the structures, making them collapse and creating enormous socio-economic problems, especially in rural areas. The solutions proposed to date, like the use of straw, cow dung, boiled skins, banana leaves, tar, cement soil, have shown their limits. Generally, the poor adhesion between the protected material and the protective layer means that the latter always ends up peeling off. This work, which is inspired by the traditional practice where plant tannins are used to brush the earthen walls to waterproof them, proposes a tri-layer coating composed of soil, powder and hydrolysable tannins extracted from the stem bark of Bridelia. This work focuses on the geotechnical characterization of the soil, the extraction of hydrolysable tannin, the manufacture of the micro-coating, the resistance tests carried out on the micro-coating, the technique of implementation and the test of evaluation of the performance of the tri-layer coating. The results obtained show that not only does the tri-layer coating adhere perfectly to the layer to protect, but it also waterproofs it and protects it against shocks.
文摘Resorbable bioceramics are attractive for medical applications such as bone substitution. Biochemical analysis on cells cultured on these biomaterials is vital to predict the impact of the materials in vivo and RNA extraction is an essential step in gene expression study using RT-qPCR. In this study, we describe simple modifications to the TRIzol? RNA extraction protocol widely used in biology and these allow high-yield extraction of RNA from cells on resorbable calcium phosphates. Without the modifications, RNA is trapped in the co-precipitated calcium compounds, rendering TRIzol? extraction method infeasible. Among the modifications, the use of extra TRIzol? to dilute the lysate before the RNA precipitation step is critical for extraction of RNA from porous ?-tricalcium phosphate (?-TCP) discs. We also investigate the rationale behind the undesirable precipitation so as to provide clues about the modifications required for other resorbable materials with high application potential in bone tissue engineering.
