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Investigating the Relationship between TyG, TyG-BMI Index and Laboratory Indicators and COVID-19 Severity
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作者 Cai Liang Huaiwu Jiang +3 位作者 Feng Pu Jing Lin Weijia Sun Yun Zhou 《Advances in Infectious Diseases》 2023年第4期641-651,共11页
Objective: The objective of this study was to investigate the relationship between the triglyceride-glucose (TyG) index, triglyceride-glucose-BMI (TyG-BMI) index, laboratory indices, and disease severity in patients w... Objective: The objective of this study was to investigate the relationship between the triglyceride-glucose (TyG) index, triglyceride-glucose-BMI (TyG-BMI) index, laboratory indices, and disease severity in patients with COVID-19. Methods: A retrospective analysis of COVID-19 patients treated at a tertiary hospital in Mianyang City, Sichuan Province, China, from 1 May to 31 May 2023 was performed. The patients were divided into two groups: 66 cases in the moderate group and 61 cases in the severe group. Additionally, 69 uninfected individuals from the medical examination center during the same period were selected as the control group. Spearman rank correlation was used to determine the correlation between the indices and COVID-19 severity. Multiple logistic regression analysis was performed to identify the factors affecting COVID-19 severity. ROC curves were constructed to assess the predictive value of the TyG and TyG-BMI indices for severe COVID-19. Results: There were significant differences in smoking and diabetes between the three groups (P Conclusion: Smoking, AST, ALB, TyG index, and TyG-BMI index are valuable in assessing the severity of COVID-19, with the TyG-BMI index having a higher predictive value than the TyG index. 展开更多
关键词 COVID-19 TyG index tyg-bmi index SEVERITY Liver Function
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TyG和TyG-BMI与冠心病患者颈动脉粥样硬化的相关性 被引量:1
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作者 李琦 李娇 +3 位作者 陈雅芳 李思 齐新 魏丽萍 《心脏杂志》 CAS 2024年第3期277-282,共6页
目的分析冠心病患者颈动脉粥样硬化与TyG及TyG-BMI的关系。方法选取2021年1月~2022年12月天津市人民医院心内科收治并进行冠脉造影和颈动脉超声检查患者592例为研究对象。依据冠脉造影结果分为正常对照组(n=103)及CAD组(n=489)。收集患... 目的分析冠心病患者颈动脉粥样硬化与TyG及TyG-BMI的关系。方法选取2021年1月~2022年12月天津市人民医院心内科收治并进行冠脉造影和颈动脉超声检查患者592例为研究对象。依据冠脉造影结果分为正常对照组(n=103)及CAD组(n=489)。收集患者临床资料,计算TyG指数和TyG-BMI水平。分析TyG和TyG-BMI与冠心病患者颈动脉病变程度的相关性。结果与正常对照组比较,CAD组TyG指数和TyGBMI水平明显升高(均P<0.01)。按照Gensini评分三分位数将患者分为三组,中分组(均P<0.05)和高分组(均P<0.01)TyG指数和TyG-BMI水平显著高于低分组。高分组TyG指数和TyG-BMI水平显著高于中分组(均P<0.01)。Spearman相关性分析显示TyG与TyG-BMI和Gensini评分呈现正相关,且TyG指数关联性更强(均P<0.01)。与颈动脉正常组相比,颈动脉粥样硬化组TyG指数更高(P<0.01),TyG-BMI更高(P<0.05)。二元Logistic回归分析发现年龄(OR=1.114,95%CI:1.05~1.18,P<0.01)与高血压(OR=2.913,95%CI:1.27~6.70,P<0.05)是颈动脉粥样硬化的独立危险因素),HDL-C(OR=0.108,95%CI:0.03~0.43,P<0.01)是保护因素。多元Logistic回归分析结果提示高水平TyG和TyG-BMI是颈动脉斑块形成的危险因素。以颈动脉正常为参照,排除混杂因素(如性别、年龄、BMI、收缩压、吸烟史、高血压病史、糖尿病史、药物服用情况)后,高TyG指数组CAD患者发生颈动脉斑块形成的风险是低TyG组的2.56倍,高TyG-BMI组发生颈动脉斑块的风险是低水平TyG-BMI组的4.35倍。Spearman相关性分析发现,TyG指数和颈动脉斑块厚度呈显著正相关(P<0.05),而TyGBMI和斑块厚度无相关。ROC曲线分析结果显示,TyG指数对冠心病患者合并颈动脉斑块形成具有较好的预测价值。结论TyG指数和TyG-BMI是冠心病患者颈动脉斑块形成的危险因素,且TyG指数对颈动脉斑块的预测价值优于TyG-BMI。 展开更多
关键词 TyG指数 tyg-bmi 冠心病 颈动脉粥样硬化 颈动脉内中膜厚度
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Impact of body mass index on adverse kidney events in diabetes mellitus patients: A systematic-review and meta-analysis 被引量:1
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作者 Jing-Fang Wan Yan Chen +2 位作者 Tian-Hua Yao Ya-Zhou Wu Huan-Zi Dai 《World Journal of Clinical Cases》 SCIE 2024年第3期538-550,共13页
BACKGROUND The incidence of chronic kidney disease among patients with diabetes mellitus(DM)remains a global concern.Long-term obesity is known to possibly influence the development of type 2 diabetes mellitus.However... BACKGROUND The incidence of chronic kidney disease among patients with diabetes mellitus(DM)remains a global concern.Long-term obesity is known to possibly influence the development of type 2 diabetes mellitus.However,no previous meta-analysis has assessed the effects of body mass index(BMI)on adverse kidney events in patients with DM.AIM To determine the impact of BMI on adverse kidney events in patients with DM.METHODS A systematic literature search was performed on the PubMed,ISI Web of Science,Scopus,Ovid,Google Scholar,EMBASE,and BMJ databases.We included trials with the following characteristics:(1)Type of study:Prospective,retrospective,randomized,and non-randomized in design;(2)participants:Restricted to patients with DM aged≥18 years;(3)intervention:No intervention;and(4)kidney adverse events:Onset of diabetic kidney disease[estimated glomerular filtration rate(eGFR)of<60 mL/min/1.73 m2 and/or microalbuminuria value of≥30 mg/g Cr],serum creatinine increase of more than double the baseline or end-stage renal disease(eGFR<15 mL/min/1.73 m2 or dialysis),or death.RESULTS Overall,11 studies involving 801 patients with DM were included.High BMI(≥25 kg/m2)was significantly associated with higher blood pressure(BP)[systolic BP by 0.20,95%confidence interval(CI):0.15–0.25,P<0.00001;diastolic BP by 0.21 mmHg,95%CI:0.04–0.37,P=0.010],serum albumin,triglycerides[standard mean difference(SMD)=0.35,95%CI:0.29–0.41,P<0.00001],low-density lipoprotein(SMD=0.12,95%CI:0.04–0.20,P=0.030),and lower high-density lipoprotein(SMD=–0.36,95%CI:–0.51 to–0.21,P<0.00001)in patients with DM compared with those with low BMIs(<25 kg/m2).Our analysis showed that high BMI was associated with a higher risk ratio of adverse kidney events than low BMI(RR:1.22,95%CI:1.01–1.43,P=0.036).CONCLUSION The present analysis suggested that high BMI was a risk factor for adverse kidney events in patients with DM. 展开更多
关键词 Obesity Body mass index Diabetes mellitus Adverse kidney events Systematic-review META-ANALYSIS
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A phenology-based vegetation index for improving ratoon rice mapping using harmonized Landsat and Sentinel-2 data 被引量:2
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作者 Yunping Chen Jie Hu +6 位作者 Zhiwen Cai Jingya Yang Wei Zhou Qiong Hu Cong Wang Liangzhi You Baodong Xu 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第4期1164-1178,共15页
Ratoon rice,which refers to a second harvest of rice obtained from the regenerated tillers originating from the stubble of the first harvested crop,plays an important role in both food security and agroecology while r... Ratoon rice,which refers to a second harvest of rice obtained from the regenerated tillers originating from the stubble of the first harvested crop,plays an important role in both food security and agroecology while requiring minimal agricultural inputs.However,accurately identifying ratoon rice crops is challenging due to the similarity of its spectral features with other rice cropping systems(e.g.,double rice).Moreover,images with a high spatiotemporal resolution are essential since ratoon rice is generally cultivated in fragmented croplands within regions that frequently exhibit cloudy and rainy weather.In this study,taking Qichun County in Hubei Province,China as an example,we developed a new phenology-based ratoon rice vegetation index(PRVI)for the purpose of ratoon rice mapping at a 30 m spatial resolution using a robust time series generated from Harmonized Landsat and Sentinel-2(HLS)images.The PRVI that incorporated the red,near-infrared,and shortwave infrared 1 bands was developed based on the analysis of spectro-phenological separability and feature selection.Based on actual field samples,the performance of the PRVI for ratoon rice mapping was carefully evaluated by comparing it to several vegetation indices,including normalized difference vegetation index(NDVI),enhanced vegetation index(EVI)and land surface water index(LSWI).The results suggested that the PRVI could sufficiently capture the specific characteristics of ratoon rice,leading to a favorable separability between ratoon rice and other land cover types.Furthermore,the PRVI showed the best performance for identifying ratoon rice in the phenological phases characterized by grain filling and harvesting to tillering of the ratoon crop(GHS-TS2),indicating that only several images are required to obtain an accurate ratoon rice map.Finally,the PRVI performed better than NDVI,EVI,LSWI and their combination at the GHS-TS2 stages,with producer's accuracy and user's accuracy of 92.22 and 89.30%,respectively.These results demonstrate that the proposed PRVI based on HLS data can effectively identify ratoon rice in fragmented croplands at crucial phenological stages,which is promising for identifying the earliest timing of ratoon rice planting and can provide a fundamental dataset for crop management activities. 展开更多
关键词 ratoon rice phenology-based ratoon rice vegetation index(PRVI) phenological phase feature selection Harmonized Landsat Sentinel-2 data
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Method for evaluation of geological strength index of carbonate cliff rocks:Coupled hyperspectral-digital borehole image technique 被引量:1
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作者 Haiqing Yang Guizhong Huang +3 位作者 Chiwei Chen Yong Yang Qi Wang Xionghui Dai 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第10期4204-4215,共12页
The deterioration of unstable rock mass raised interest in evaluating rock mass quality.However,the traditional evaluation method for the geological strength index(GSI)primarily emphasizes the rock structure and chara... The deterioration of unstable rock mass raised interest in evaluating rock mass quality.However,the traditional evaluation method for the geological strength index(GSI)primarily emphasizes the rock structure and characteristics of discontinuities.It ignores the influence of mineral composition and shows a deficiency in assessing the integrity coefficient.In this context,hyperspectral imaging and digital panoramic borehole camera technologies are applied to analyze the mineral content and integrity of rock mass.Based on the carbonate mineral content and fissure area ratio,the strength reduction factor and integrity coefficient are calculated to improve the GSI evaluation method.According to the results of mineral classification and fissure identification,the strength reduction factor and integrity coefficient increase with the depth of rock mass.The rock mass GSI calculated by the improved method is mainly concentrated between 40 and 60,which is close to the calculation results of the traditional method.The GSI error rates obtained by the two methods are mostly less than 10%,indicating the rationality of the hyperspectral-digital borehole image coupled evaluation method.Moreover,the sensitivity of the fissure area ratio(Sr)to GSI is greater than that of the strength reduction factor(a),which means the proposed GSI is suitable for rocks with significant fissure development.The improved method reduces the influence of subjective factors and provides a reliable index for the deterioration evaluation of rock mass. 展开更多
关键词 Hyperspectral image Digital panoramic borehole image Geological strength index Carbonate rock mass Quantitative evaluation
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Spectral purification improves monitoring accuracy of the comprehensive growth evaluation index for film-mulched winter wheat 被引量:1
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作者 Zhikai Cheng Xiaobo Gu +5 位作者 Yadan Du Zhihui Zhou Wenlong Li Xiaobo Zheng Wenjing Cai Tian Chang 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第5期1523-1540,共18页
In order to further improve the utility of unmanned aerial vehicle(UAV)remote-sensing for quickly and accurately monitoring the growth of winter wheat under film mulching, this study examined the treatments of ridge m... In order to further improve the utility of unmanned aerial vehicle(UAV)remote-sensing for quickly and accurately monitoring the growth of winter wheat under film mulching, this study examined the treatments of ridge mulching,ridge–furrow full mulching, and flat cropping full mulching in winter wheat.Based on the fuzzy comprehensive evaluation (FCE) method, four agronomic parameters (leaf area index, above-ground biomass, plant height, and leaf chlorophyll content) were used to calculate the comprehensive growth evaluation index (CGEI) of the winter wheat, and 14 visible and near-infrared spectral indices were calculated using spectral purification technology to process the remote-sensing image data of winter wheat obtained by multispectral UAV.Four machine learning algorithms, partial least squares, support vector machines, random forests, and artificial neural network networks(ANN), were used to build the winter wheat growth monitoring model under film mulching, and accuracy evaluation and mapping of the spatial and temporal distribution of winter wheat growth status were carried out.The results showed that the CGEI of winter wheat under film mulching constructed using the FCE method could objectively and comprehensively evaluate the crop growth status.The accuracy of remote-sensing inversion of the CGEI based on the ANN model was higher than for the individual agronomic parameters, with a coefficient of determination of 0.75,a root mean square error of 8.40, and a mean absolute value error of 6.53.Spectral purification could eliminate the interference of background effects caused by mulching and soil, effectively improving the accuracy of the remotesensing inversion of winter wheat under film mulching, with the best inversion effect achieved on the ridge–furrow full mulching area after spectral purification.The results of this study provide a theoretical reference for the use of UAV remote-sensing to monitor the growth status of winter wheat with film mulching. 展开更多
关键词 mulched winter wheat machine learning fuzzy comprehensive evaluation comprehensive growth evaluation index unmanned aerial vehicle
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Association between triglyceride-glucose index and colorectal polyps:A retrospective cross-sectional study 被引量:1
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作者 Ya-Jie Teng Ying-Xue Yang +5 位作者 Jing-Jing Yang Qiu-Yan Lu Jia-Yi Shi Jian-Hao Xu Jie Bao Qing-Hua Wang 《World Journal of Gastrointestinal Endoscopy》 2024年第2期55-63,共9页
BACKGROUND Colorectal polyps(CPs)are frequently occurring abnormal growths in the colorectum,and are a primary precursor of colorectal cancer(CRC).The triglyceride-glucose(TyG)index is a novel marker that assesses met... BACKGROUND Colorectal polyps(CPs)are frequently occurring abnormal growths in the colorectum,and are a primary precursor of colorectal cancer(CRC).The triglyceride-glucose(TyG)index is a novel marker that assesses metabolic health and insulin resistance,and has been linked to gastrointestinal cancers.AIM To investigate the potential association between the TyG index and CPs,as the relation between them has not been documented.METHODS A total of 2537 persons undergoing a routine health physical examination and colonoscopy at The First People's Hospital of Kunshan,Jiangsu Province,China,between January 2020 and December 2022 were included in this retrospective cross-sectional study.After excluding individuals who did not meet the eligibility criteria,descriptive statistics were used to compare characteristics between patients with and without CPs.Logistic regression analyses were conducted to determine the associations between the TyG index and the prevalence of CPs.The TyG index was calculated using the following formula:Ln[triglyceride(mg/dL)×glucose(mg/dL)/2].The presence and types of CPs was determined based on data from colonoscopy reports and pathology reports.RESULTS A nonlinear relation between the TyG index and the prevalence of CPs was identified,and exhibited a curvilinear pattern with a cut-off point of 2.31.A significant association was observed before the turning point,with an odds ratio(95% confidence interval)of 1.70(1.40,2.06),P<0.0001.However,the association between the TyG index and CPs was not significant after the cut-off point,with an odds ratio(95% confidence interval)of 0.57(0.27,1.23),P=0.1521.CONCLUSION Our study revealed a curvilinear association between the TyG index and CPs in Chinese individuals,suggesting its potential utility in developing colonoscopy screening strategies for preventing CRC. 展开更多
关键词 Triglyceride-glucose index Colorectal polyps Colorectal cancer Insulin resistance Cross-sectional study
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Renal resistive index measurements by ultrasound in patients with liver cirrhosis:Magnitude and associations with renal dysfunction 被引量:1
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作者 Himanshu Surya Ramesh Kumar +2 位作者 Rajeev Nayan Priyadarshi Sabbu Surya Prakash Sudhir Kumar 《World Journal of Radiology》 2024年第6期221-231,共11页
BACKGROUND The hemodynamic alterations seen in liver cirrhosis lead to renal vasoconstriction,ultimately causing acute kidney injury(AKI).The renal resistive index(RRI)is the most common Doppler ultrasound variable fo... BACKGROUND The hemodynamic alterations seen in liver cirrhosis lead to renal vasoconstriction,ultimately causing acute kidney injury(AKI).The renal resistive index(RRI)is the most common Doppler ultrasound variable for measuring intrarenal vascular resistance.AIM To evaluate the association of the RRI with AKI in patients with liver cirrhosis and to identify risk factors for high RRI.METHODS This was a prospective observational study,where RRI was measured using Doppler ultrasound in 200 consecutive hospitalized patients with cirrhosis.The association of RRI with AKI was studied.The receiver operating characteristic(ROC)curve analysis was utilized to determine discriminatory cut-offs of RRI for various AKI phenotypes.Multivariate analysis was conducted to determine the predictors of high RRI.RESULTS The mean patient age was 49.08±11.68 years,with the majority(79.5%)being male;the predominant etiology of cirrhosis was alcohol(39%).The mean RRI for the study cohort was 0.68±0.09,showing a progressive increase with higher Child-Pugh class of cirrhosis.Overall,AKI was present in 129(64.5%)patients.The mean RRI was significantly higher in patients with AKI compared to those without it(0.72±0.06 vs 0.60±0.08;P<0.001).A total of 82 patients(41%)had hepatorenal syndrome(HRS)-AKI,29(22.4%)had prerenal AKI(PRA),and 18(13.9%)had acute tubular necrosis(ATN)-AKI.The mean RRI was significantly higher in the ATN-AKI(0.80±0.02)and HRS-AKI(0.73±0.03)groups than in the PRA(0.63±0.07)and non-AKI(0.60±0.07)groups.RRI demonstrated excellent discriminatory ability in distinguishing ATN-AKI from non-ATN-AKI(area under ROC curve:93.9%).AKI emerged as an independent predictor of high RRI(adjusted odds ratio[OR]:11.52),and high RRI independently predicted mortality among AKI patients(adjusted OR:3.18).CONCLUSION In cirrhosis patients,RRI exhibited a significant association with AKI,effectively differentiated between AKI phenotypes,and predicted AKI mortality. 展开更多
关键词 Renal resistive index CIRRHOSIS Acute kidney injury Hepatorenal syndrome Renal Doppler
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Three-dimensional choroidal vascularity index and choroidal thickness in fellow eyes of acute and chronic primary angle-closure using swept-source optical coherence tomography 被引量:1
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作者 Hai-Li Huang Guan-Hong Wang +1 位作者 Liang-Liang Niu Xing-Huai Sun 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第1期42-52,共11页
AIM:To compare the three-dimensional choroidal vascularity index(CVI)and choroidal thickness between fellow eyes of acute primary angle-closure(F-APAC)and chronic primary angle-closure glaucoma(F-CPACG)and the eyes of... AIM:To compare the three-dimensional choroidal vascularity index(CVI)and choroidal thickness between fellow eyes of acute primary angle-closure(F-APAC)and chronic primary angle-closure glaucoma(F-CPACG)and the eyes of normal controls.METHODS:This study included 37 patients with unilateral APAC,37 with asymmetric CPACG without prior treatment,and 36 healthy participants.Using swept-source optical coherence tomography(SS-OCT),the macular and peripapillary choroidal thickness and three-dimensional CVI were measured and compared globally and sectorally.Pearson’s correlation analysis and multivariate regression models were used to evaluate choroidal thickness or CVI with related factors.RESULTS:The mean subfoveal CVIs were 0.35±0.10,0.33±0.09,and 0.29±0.04,and the mean subfoveal choroidal thickness were 315.62±52.92,306.22±59.29,and 262.69±45.55μm in the F-APAC,F-CPACG,and normal groups,respectively.All macular sectors showed significantly higher CVIs and choroidal thickness in the F-APAC and F-CPACG eyes than in the normal eyes(P<0.05),while there were no significant differences between the F-APAC and F-CPACG eyes.In the peripapillary region,the mean overall CVIs were 0.21±0.08,0.20±0.08,and 0.19±0.05,and the mean overall choroidal thickness were 180.45±54.18,174.82±50.67,and 176.18±37.94μm in the F-APAC,F-CPACG,and normal groups,respectively.There were no significant differences between any of the two groups in all peripapillary sectors.Younger age,shorter axial length,and the F-APAC or F-CPACG diagnosis were significantly associated with higher subfoveal CVI and thicker subfoveal choroidal thickness(P<0.05).CONCLUSION:The fellow eyes of unilateral APAC or asymmetric CPACG have higher macular CVI and choroidal thickness than those of the normal controls.Neither CVI nor choroidal thickness can distinguish between eyes predisposed to APAC or CPACG.A thicker choroid with a higher vascular volume may play a role in the pathogenesis of primary angle-closure glaucoma. 展开更多
关键词 choroidal thickness choroidal vascularity index swept-source optical coherence tomography acute primary angle-closure chronic primary angle-closure glaucoma
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On traceable iterated line graph and hamiltonian path index
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作者 NIU Zhao-hong XIONG Li-ming YANG Wei-hua 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2024年第2期239-252,共14页
Xiong and Liu[21]gave a characterization of the graphs G for which the n-iterated line graph L^(n)(G)is hamiltonian,for n≥2.In this paper,we study the existence of a hamiltonian path in L^(n)(G),and give a characteri... Xiong and Liu[21]gave a characterization of the graphs G for which the n-iterated line graph L^(n)(G)is hamiltonian,for n≥2.In this paper,we study the existence of a hamiltonian path in L^(n)(G),and give a characterization of G for which L^(n)(G)has a hamiltonian path.As applications,we use this characterization to give several upper bounds on the hamiltonian path index of a graph. 展开更多
关键词 iterated line graph TRACEABLE hamiltonian index hamiltonian path index
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Predictive Value of Systemic Immune Inflammation Index, Aggregate Index of Systemic Inflammation, and Systemic Inflammation Response Index in Lower Extremity Deep Venous Thrombosis Following Severe Trauma
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作者 Peng-Fei Li Xin Lu +4 位作者 Yu-Qian Zhou Ke Wang Peng Yang Xiong-Hui Chen Feng Xu 《Chinese Medical Sciences Journal》 CAS CSCD 2024年第4期241-248,共8页
Objective Venous thromboembolism is a highly prevalent condition after polytrauma,and recognized as an important factor contributing to poor prognosis.The aim of this study was to investigate the risk factors for lowe... Objective Venous thromboembolism is a highly prevalent condition after polytrauma,and recognized as an important factor contributing to poor prognosis.The aim of this study was to investigate the risk factors for lower extremity deep venous thrombosis(LEDVT)in a severely traumatized population and to evaluate their predictive value for LEDVT.Methods This was a retrospective,single-center observational study.All subjects were severely traumatized patients who were admitted to the Traumatic Intensive Care Unit from January 2021 to May 2024.Based on Doppler ultrasound findings of both lower extremities from the time of injury to 30 days post-injury,patients who developed LEDVT were enrolled in the LEDVT group,and those who did not develop LEDVT were enrolled in the NLEDVT group.Demographic,clinical,and laboratory data were collected upon admission.Multivariable logistic regression analysis was performed to identify risk factors for LEDVT.Receiver operating characteristic(ROC)curve was used to evaluate the overall fit of the final model.Results There were 56 patients enrolled in the LEDVT group and 81 patients in the NLEDVT group.Age,Aggregate Index of Systemic Inflammation(AISI),Systemic Inflammation Response Index(SIRI),ICU length of stay,and albumin were identified as independent risk factors for LEDVT(all P<0.05).The area under their ROC curves were 0.604,0.657,0.694,0.668,and 0.405,respectively.Combined model for early clinical prediction of LEDVT in severely traumatized patients by age,SIRI,AISI,and albumin resulted in an area under the ROC curve of 0.805(95%CI:0.73-0.88,SE=0.037).Conclusion The combination of age,SIRI,AISI,and albumin has a predictive value for LEDVT in severely traumatized patients. 展开更多
关键词 severe trauma Systemtic Immune Inflammation index Aggregate index of Systemic Inflammation Systemic Inflammation Response index lower extremity deep venous thrombosis
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Association between the cumulative triglyceride-glucose index and the recurrence of atrial fibrillation after radiofrequency catheter ablation
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作者 Qing YAN Jia-Qi LIANG +5 位作者 Yi-De YUAN Yuan LI Jia-Li FAN Wen-Huan WU Pan XU Jia-Hong XUE 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2024年第2期200-210,共11页
BACKGROUND Triglyceride-glucose(TyG)index values are a new surrogate marker for insulin resistance.This study aimed to explore the relationship between cumulative TyG index values and atrial fibrillation(AF)recurrence... BACKGROUND Triglyceride-glucose(TyG)index values are a new surrogate marker for insulin resistance.This study aimed to explore the relationship between cumulative TyG index values and atrial fibrillation(AF)recurrence after radiofrequency catheter ablation(RFCA).METHODS A total of 576 patients with AF who underwent RFCA at the Second Affiliated Hospital of Xi'an Jiaotong University were included in this study.The participants were grouped based on cumulative TyG index values tertiles within 3 months after ablation.Cox regression and restricted cubic spline analyses were used to determine the relationship between cumulative TyG index values and AF recurrence.The predictive value of all risk factors was assessed by receiver operating curve analysis.RESULTS There were 375 patients completed the study(age:63.23±10.73 years,64.27%male).The risk of AF recurrence increased with increasing cumulative TyG index values tertiles.After adjusting for potential confounders,patients in the medium cumulative TyG index group[hazard ratio(HR)=4.949,95%CI:1.778–13.778,P=0.002]and the high cumulative TyG index group(HR=8.716,95%CI:3.371–22.536,P<0.001)had a higher risk of AF recurrence than those in the low cumulative TyG index group.The restricted cubic spline regression model also showed an increased risk of AF recurrence with increasing cumulative TyG index values.When considering cumulative TyG index values,left atrial diameter,and lactate dehydrogenase levels as a comprehensive factor,the model could effectively predict AF recurrence after RFCA[area under the curve(AUC)=0.847,95%CI:0.797–0.897,P<0.001].CONCLUSIONS Cumulative TyG index values were a risk factor for AF recurrence after RFCA.Monitoring longitudinal TyG index values may assist with optimized for risk stratification and outcome prediction for AF recurrence. 展开更多
关键词 ATRIAL FIBRILLATION index
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An evaluation of ureteral diameter ratio and vesicoureteral reflux index in the treatment of primary vesicoureteral reflux
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作者 Yusuf Atakan Baltrak Nebil Akdogan +3 位作者 Mutlu Deger Volkan Izol Ibrahim Atilla Aridogan Nihat Satar 《Asian Journal of Urology》 CSCD 2024年第3期437-442,共6页
Objective:Vesicoureteral reflux(VUR)index is a simple,validated tool that reliably predicts significant improvement and spontaneous resolution of primary reflux in children.The aim of this study was to evaluate and co... Objective:Vesicoureteral reflux(VUR)index is a simple,validated tool that reliably predicts significant improvement and spontaneous resolution of primary reflux in children.The aim of this study was to evaluate and compare the ureter diameter ratio(UDR)and VUR index(VURx)of patients treated with endoscopic injection(EI)and ureteroneocystostomy(UNC)methods in the pediatric age group due to primary VUR.Methods:Patients under the age of 18 years old who underwent EI and UNC with the diagnosis of primary VUR between January 2011 and September 2021 were determined as the participants.The UDR was assessed using voiding cystourethrography,and the VURx score was determined prior to treatment based on hospital records included in the study.Results:A total of 255 patients,60(23.5%)boys and 195(76.5%)girls,with a mean age of 76.5(range 13.0e204.0)months,were included in the study.EI was applied to 130(51.0%)patients and UNC was applied to 125(49.0%)patients due to primary VUR.The optimum cut-off for the distal UDR was obtained as 0.17 with sensitivity and specificity of 73.0%and 63.0%,respectively.The positive and negative predictive values were 66.0%and 70.0%,respectively.Conclusion:When the UDR and VURx score are evaluated together for the surgical treatment of primary VUR in the pediatric age group,it is thought that it may be useful in predicting the clinical course of the disease and evaluating surgical treatment options. 展开更多
关键词 Distal ureter diameter ratio Vesicoureteral reflux Vesicoureteral reflux index management Vesicoureteral reflux index
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Assessment on eco-environmental quality of the Yellow River Basin by considering desertification index
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作者 AN Min MENG Fan +4 位作者 HE Weijun XUE Fang SONG Mengfei XIE Ping WANG Bei 《Journal of Mountain Science》 SCIE CSCD 2024年第10期3275-3292,共18页
Desertification has had a significant impact on the ecological environment of the Yellow River Basin(YRB)in China.However,previous studies on the evaluation of the ecological environment quality(EEQ)in the YRB have pa... Desertification has had a significant impact on the ecological environment of the Yellow River Basin(YRB)in China.However,previous studies on the evaluation of the ecological environment quality(EEQ)in the YRB have paid limited attention to the indicator of desertification.It is of great significance to incorporate the desertification index into the spatiotemporal assessment of the EEQ in the YRB in order to protect the ecological environment in the region.In this study,based on multi-source remote sensing data from 91 cities in the YRB,this article proposes a desertification remote sensing ecological index(DRSEI)model,which builds upon the traditional Remote Sensing Ecological Index(RSEI)model,to analyze the spatiotemporal changes in the EEQ in the YRB from 2001 to 2021.Furthermore,using the geographic detector(GD),and geographically and temporally weighted regression(GTWR)model,the study assesses the impact of human and natural factors on the EEQ in the YRB.The research findings indicate that:(1)Compared to the traditional RSEI,the improved DRSEI shows a decreasing trend in the evaluation results of the EEQ.Among the 24 cities,the change in DRSEI exceeds 0.05 compared to RSEI,accounting for 26.37%of the YRB.The remaining 67 cities have changes within a range of less than 0.05,accounting for 73.63%of the YRB.(2)The results of the GD for individual and interactive effects reveal that rainfall and elevation have significant individual and interactive effects on the EEQ.Furthermore,after the interaction with natural factors,the explanatory power of human factors gradually increases over time.The spatial heterogeneity results of GTWR demonstrate that rainfall has a strong direct positive impact on the EEQ,accounting for 98.90%of the influence,while temperature exhibits a more pronounced direct inhibitory effect,accounting for 76.92%of the influence.Human activities have a strong negative impact on the EEQ and a weak positive impact. 展开更多
关键词 Ecological environment quality Desertification index Desertification remote sensing ecological index Driving factors Yellow River Basin
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Prognostic value of combined systemic inflammation response index and prognostic nutritional index in colorectal cancer patients
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作者 Ke-Jin Li Zi-Yi Zhang +5 位作者 Subinur Sulayman Yin Shu Kuan Wang Saibihutula Ababaike Xiang-Yue Zeng Ze-Liang Zhao 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第12期3794-3805,共12页
BACKGROUND The prognosis of colorectal cancer(CRC)patients is notably influenced by both inflammation and nutritional status.The prognostic nutritional index(PNI)and systemic inflammatory response index(SIRI)have been... BACKGROUND The prognosis of colorectal cancer(CRC)patients is notably influenced by both inflammation and nutritional status.The prognostic nutritional index(PNI)and systemic inflammatory response index(SIRI)have been reported in prognostic studies of various tumors.However,the efficacy of the combination of the two in predicting the prognosis of CRC patients has not been studied.AIM To evaluate the effectiveness of PNI and SIRI in predicting the prognosis of patients with CRC.METHODS We retrospectively gathered data from 470 CRC patients who underwent feasible radical surgery at Xinjiang Cancer Hospital.The optimal cut-off values for SIRI and PNI,along with their predictive power for survival,were determined through area under the receiver operating characteristic curve using time-dependent receiver operating characteristic analysis.The Kaplan-Meier method and log-rank test were applied to assess prognostic impact,and a multifactorial Cox proportional hazards model was employed for analysis.Additionally,a new model,PSIRI,was developed and assessed for its survival prediction capability.RESULTS The optimal cutoff values for PNI and SIRI were determined to be 47.80 and 1.38,respectively.Based on these values,patients were categorized into high PNI and low PNI groups,as well as high SIRI and low SIRI groups.Significant differences in age,T stage,neutrophil to lymphocyte ratio(NLR),monocyte to lymphocyte ratio(MLR),and platelet-to-lymphocyte ratio(PLR)subgroups were observed between the PNI groups in the baseline profile.In the SIRI group,notable differences were found in gender,T stage,nerve invasion,intravascular tumor emboli,NLR,MLR,and PLR subgroups.Both low PNI and high SIRI were identified as independent risk factors for poor prognosis in CRC patients.When combined into the PSIRI model,it was shown that patients with a PSIRI≤1 had a higher risk of death compared to those with a PSIRI of 2.CONCLUSION We assessed the impact of PNI and SIRI on the prognostic survival of CRC patients and developed a new model,PSIRI.This model demonstrated superior predictive accuracy,with a concordance index of 0.767. 展开更多
关键词 Colorectal cancer Prognostic nutritional index Systemic inflammatory response index PROGNOSIS
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Early peripheral perfusion index predicts 28-day outcome in patients with septic shock
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作者 Cheng Chi Hao Gong +2 位作者 Kai Yang Peng Peng Xiaoxia Zhang 《World Journal of Emergency Medicine》 SCIE CAS CSCD 2024年第5期372-378,共7页
BACKGROUND:To investigate the prognostic value of the peripheral perfusion index(PPI)in patients with septic shock.METHODS:This prospective cohort study,conducted at the emergency intensive care unit of Peking Univers... BACKGROUND:To investigate the prognostic value of the peripheral perfusion index(PPI)in patients with septic shock.METHODS:This prospective cohort study,conducted at the emergency intensive care unit of Peking University People's Hospital,recruited 200 patients with septic shock between January 2023 and August 2023.These patients were divided into survival(n=84)and death(n=116)groups based on 28-day outcomes.Clinical evaluations included laboratory tests and clinical scores,with lactate and PPI values assessed upon admission to the emergency room and at 6 h and 12 h after admission.Risk factors associated with mortality were analyzed using univariate and multivariate Cox regression analyses.Receiver operator characteristic(ROC)curve was used to assess predictive performance.Mortality rates were compared,and Kaplan-Meier survival plots were created.RESULTS:Compared to the survival group,patients in the death group were older and had more severe liver damage and coagulation dysfunction,necessitating higher norepinephrine doses and increased fl uid replacement.Higher lactate levels and lower PPI levels at 0 h,6 h,and 12 h were observed in the death group.Multivariate Cox regression identifi ed prolonged prothrombin time(PT),decreased 6-h PPI and 12-h PPI as independent risk factors for death.The area under the curves for 6-h PPI and 12-h PPI were 0.802(95%CI 0.742-0.863,P<0.001)and 0.945(95%CI 0.915-0.974,P<0.001),respectively,which were superior to Glasgow Coma Scale(GCS),Sequential Organ Failure Assessment(SOFA)scores(0.864 and 0.928).Cumulative mortality in the low PPI groups at 6 h and 12 h was signifi cantly higher than in the high PPI groups(6-h PPI:77.52%vs.22.54%;12-h PPI:92.04%vs.13.79%,P<0.001).CONCLUSION:PPI may have value in predicting 28-day mortality in patients with septic shock. 展开更多
关键词 Peripheral perfusion index Septic shock PROGNOSIS Predictive value
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Actuality and underlying mechanisms of systemic immuneinflammation index and geriatric nutritional risk index prognostic value in hepatocellular carcinoma
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作者 Konstantin Y Tchilikidi 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第2期260-265,共6页
This editorial contains comments on the article“Correlation between preoperative systemic immune inflammation index,nutritional risk index,and prognosis of radical resection of liver cancer”in a recent issue of the ... This editorial contains comments on the article“Correlation between preoperative systemic immune inflammation index,nutritional risk index,and prognosis of radical resection of liver cancer”in a recent issue of the World Journal of Gastrointestinal Surgery.It pointed out the actuality and importance of the article and focused primarily on the underlying mechanisms making the systemic immuneinflammation index(SII)and geriatric nutritional risk index(GNRI)prediction features valuable.There are few publications on both SII and GNRI together in hepatocellular carcinoma(HCC)and patient prognosis after radical surgery.Neutrophils release cytokines,chemokines,and enzymes,degrade extracellular matrix,reduce cell adhesion,and create conditions for tumor cell invasion.Neutrophils promote the adhesion of tumor cells to endothelial cells,through physical anchoring.That results in the migration of tumor cells.Pro-angiogenic factors from platelets enhance tumor angiogenesis to meet tumor cell supply needs.Platelets can form a protective film on the surface of tumor cells.This allows avoiding blood flow damage as well as immune system attack.It also induces the epithelial-mesenchymal transformation of tumor cells that is critical for invasiveness.High SII is also associated with macro-and microvascular invasion and increased numbers of circulating tumor cells.A high GNRI was associated with significantly better progression-free and overall survival.HCC patients are a very special population that requires increased attention.SII and GNRI have significant survival prediction value in both palliative treatment and radical surgery settings.The underlying mechanisms of their possible predictive properties lie in the field of essential cancer features.Those features provide tumor nutrition,growth,and distribution throughout the body,such as vascular invasion.On the other hand,they are tied to the possibility of patients to resist tumor progression and development of complications in both postoperative and cancer-related settings.The article is of considerable interest.It would be helpful to continue the study follow-up to 2 years and longer.External validation of the data is needed. 展开更多
关键词 Systemic immune-inflammation index Geriatric nutritional risk index Radical surgery Transarterial chemoembolization Hepatocellular carcinoma Prognosis
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Advancing prognostic precision in gastric cancer with an immunoinflammatory index
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作者 Hong-Mei Zhang Guo-Hua Wang +1 位作者 Shan-Wen Sun Lei Yuan 《World Journal of Gastroenterology》 SCIE CAS 2024年第44期4754-4758,共5页
Gastric cancer remains a major global health challenge with high morbidity and mortality rates.Recent advancements in immunology and inflammation research have highlighted the crucial roles that these biological proce... Gastric cancer remains a major global health challenge with high morbidity and mortality rates.Recent advancements in immunology and inflammation research have highlighted the crucial roles that these biological processes play in tumor progression and patient outcomes.This has sparked new interest in developing prognostic biomarkers that integrate these two key biological processes.In this letter,we discuss the recent study by Ba et al,which proposed a novel prognostic immunoinflammatory index for patients with gastric cancer.We underscore the importance of this research,its potential impact on medical practice,and the prospective avenues for further investigation in this rapidly emerging area of study. 展开更多
关键词 Gastric cancer Immunoinflammatory index Prognostic biomarkers INFLAMMATION IMMUNOLOGY
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A Transparent Photoresist Made of Titanium Dioxide Nanoparticle-Embedded Acrylic Resin with a Tunable Refractive Index for UV-Imprint Lithography
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作者 Yinglu Liu Dan Wang +7 位作者 Changlin Liu Qianqian Hao Jian Li Jie-Xin Wang Xiuyun Chen Peng Zhong Xibin Shao Jian-Feng Chen 《Engineering》 SCIE EI CAS CSCD 2024年第6期96-104,共9页
Transparent photoresists with a high refractive index(RI)and high transmittance in visible wavelengths have promising functionalities in optical fields.This work reports a kind of tunable optical material composed of ... Transparent photoresists with a high refractive index(RI)and high transmittance in visible wavelengths have promising functionalities in optical fields.This work reports a kind of tunable optical material composed of titanium dioxide nanoparticles embedded in acrylic resin with a high RI for ultraviolet(UV)-imprint lithography.The hybrid film exhibits a tunable RI of up to 1.67(589 nm)after being cured by UV light,while maintaining both a high transparency of over 98%in the visible light range and a low haze of less than 0.05%.The precision machining of optical microstructures can be imprinted easily and efficiently using the hybrid resin,which acts as a light guide plate(LGP)to guide the light from the side to the top in order to conserve the energy of the display device.These preliminary studies based on both laboratory and commercial experiments pave the way for exploiting the unparalleled optical properties of nanocomposite resins and promoting their industrial application. 展开更多
关键词 PHOTORESIST Tunable refractive index Hanson solubility Ultraviolet imprint Organic-inorganic composites
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Analysis and construction of evaluation index system of inter-provincial electricity spot markets
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作者 Hao Yue Yu Zhang +5 位作者 Jiahao Guo Yang Hu Chengmei Wei Heping Jia Dunnan Liu Dunjian Xie 《Global Energy Interconnection》 EI CSCD 2024年第6期697-706,共10页
Because of the contradiction between the scale of new energy installations and the continuous load growth in the central and eastern regions of China,the balance problems of the electricity market are becoming increas... Because of the contradiction between the scale of new energy installations and the continuous load growth in the central and eastern regions of China,the balance problems of the electricity market are becoming increasingly prominent,and it is urgent to solve such problems through inter-provincial electricity spot markets.First,the development history and construction status of the inter-provincial electricity spot market are summarized;second,the mechanism design of the inter-provincial electricity spot market is sorted out in terms of the market operation framework,transaction declaration,and clearing methods;subsequently,the evaluation index system of the inter-provincial electricity spot market is constructed,including four themes of electricity mutual aid and support,new energy consumption,economic benefits of market-based allocation,and social benefits of market-based allocation;finally,the operation of the inter-provincial electricity spot market is comprehensively analyzed by the algorithm based on the market operation data of 2022,which proves the feasibility and practicality of the proposed index system. 展开更多
关键词 Electricity market Spot market Inter-provincial spot market Evaluation index system
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