Traditional Chinese Medicine-Based Subtyping of Early-Stage Type 2 Diabetes Using Plasma Metabolomics Combined with Ultra-Weak Photon Emission

The prevalence of type 2 diabetes mellitus(T2DM)is increasing rapidly worldwide.Because of the limited success of generic interventions,the focus of the disease study has shifted toward personalized strategies,particularly in the early stages of the disease.Traditional Chinese medicine(TCM)is based on a systems view combined with personalized strategies and has improved our knowledge of personalized diagnostics.From a systems biology perspective,the understanding of personalized diagnostics can be improved to yield a biochemical basis for such strategies;for example,metabolomics can be used in combination with other system-based diagnostic methods such as ultra-weak photon emission(UPE).In this study,we investigated the feasibility of using plasma metabolomics obtained from 44 pre-T2DM subjects to stratify the following TCM-based subtypes:Qi-Yin deficiency,Qi-Yin deficiency with dampness,and Qi-Yin deficiency with stagnation.We studied the relationship between plasma metabolomics and UPE with respect to TCM-based subtyping in order to obtain biochemical information for further interpreting disease subtypes.Principal component analysis of plasma metabolites revealed differences among the TCM-based pre-T2DM subtypes.Relatively high levels of lipids(e.g.,cholesterol esters and triglycerides)were important discriminators of two of the three subtypes and may be associated with a higher risk of cardiovascular disease.Plasma metabolomics data indicate that the lipid profile is an essential component captured by UPE with respect to stratifying subtypes of T2DM.The results suggest that metabolic differences exist among different TCM-based subtypes of pre-T2DM,and profiling plasma metabolites can be used to discriminate among these subtypes.Plasma metabolomics thus provides biochemical insights into system-based UPE measurements.

An Adaptive Multiresolution Ultra-weak Discontinuous Galerkin Method for Nonlinear Schrödinger Equations

This paper develops a high-order adaptive scheme for solving nonlinear Schrödinger equa-tions.The solutions to such equations often exhibit solitary wave and local structures,which make adaptivity essential in improving the simulation efficiency.Our scheme uses the ultra-weak discontinuous Galerkin(DG)formulation and belongs to the framework of adaptive multiresolution schemes.Various numerical experiments are presented to demon-strate the excellent capability of capturing the soliton waves and the blow-up phenomenon.

The Role of Consciousness in Healing Therapies: A Brief History of Ancestral Energies, Biofield and Ultra-Weak Photon Emission

Healing therapies are a set of techniques used with the aim of transfusing healthy “bioenergy” to other people in order to restore physical, mental, and emotional balance. It is necessary that something is donated from the healer, that is, something results from his organic metabolism. Also, based on your physical, mental, and emotional health, the energy resulting from your metabolism is assumed to be healthy for the healing of patients. On the other hand, also in many cases, healing does not occur due to the “vicious” quality of the energy to be transfused and the low receptivity of the patient. However, in most cases, it depends not only on the healer but also on the receiver, but usually on other healers, such as higher order consciousnesses. In fact, in many cases of healing, the effect is almost instantaneous with just the healer’s “magnetic energy”, especially in painful crises. Without a doubt, I believe that biophoton is an anti-inflammatory, analgesic, antibacterial and immunomodulatory bioenergy. The healing effectiveness of these therapies is well established. It is a cell-restoring product that can rebuild tissues and organs in a short time, which in many cases leads to the restoration of the patient’s health and well-being. The aim of this study is to address a brief history of ancestral energies of Asian philosophy (Chinese, Japanese and Indian), highlight the role of consciousness and the healer in healing therapies. In addition, the study emphasizes the similarity of these energies with the one called “ectoplasm”, as well as it establishes connections with the newly elected ultra-weak emission of photons. Finally, bibliographic research was carried out in an English language database and innovative concepts were introduced about the role of consciousness as well as the healer in healing therapies.

Perimeter Security System Based on Ultra-Weak Fiber Bragg Grating Array

A perimeter security system based on ultra-weak fiber Bragg grating high-speed wavelength demodulation was proposed. The demodulation system for signal acquisition and high-speed wavelength calculation was designed based on field programmable gate array (FPGA) platform. The principle of ultra-weak fiber Bragg grating high-speed demodulation and signal recognition method were analyzed theoretically, and the Support Vector Machine model was introduced to optimize the event recognition accuracy of the system. A perimeter security experimental system containing 1000 ultra-weak fiber Bragg gratings, ultra-weak fiber Bragg grating sense optical cables with a diameter of 2.0 mm and a reflectivity of 0.01%, steel space frames and demodulation equipments was built to recognize four typical events such as knocking, shaking, wind blowing and rainfall. The experimental resulted show that the system has a spatial resolution of 1m and an acquisition frequency of 200 Hz. The joint time-frequency domain detection method is used to achieve 99.2% alarm accuracy, and 98% recognition accuracy of two intrusion events, which has good anti-interference performance.

ANALYSIS OF THE IMPLICIT-EXPLICIT ULTRA-WEAK DISCONTINUOUS GALERKIN METHOD FOR CONVECTION-DIFFUSION PROBLEMS

In this paper,we first present the optimal error estimates of the semi-discrete ultra-weak discontinuous Galerkin method for solving one-dimensional linear convection-diffusion equations.Then,coupling with a kind of Runge-Kutta type implicit-explicit time discretization which treats the convection term explicitly and the diffusion term implicitly,we analyze the stability and error estimates of the corresponding fully discrete schemes.The fully discrete schemes are proved to be stable if the time-stepτ≤τ0,whereτ0 is a constant independent of the mesh-size h.Furthermore,by the aid of a special projection and a careful estimate for the convection term,the optimal error estimate is also obtained for the third order fully discrete scheme.Numerical experiments are displayed to verify the theoretical results.

大跨越架空输电导线铝部应力分布试验

为了掌握大跨越架空输电导线铝部应力空间分布特性,以JLHA1/G6A-500/280型特强钢芯铝合金导线为研究对象,采用铝股丝表面激光刻槽,内嵌高灵敏、超大复用容量超弱光纤光栅,搭建了大跨越输电导线铝部应力试验平台,研究了不同张力条件下大跨越架空输电导线铝部应力分布规律,建立了大跨越导线实体有限元模型,分析了铝股应力分布特征,并验证了试验结果的正确性。结果表明:导线承受张力作用时,外层铝股和次外层铝股应力不同,外层铝股应力小于次外层铝股应力,导线同层铝股应力基本相同;铝股应力随导线张力的增大呈线性增大趋势,张力每增大1%,铝股应力增大约10%。不同导线张力作用时钢股和铝股应力均呈现环状分层特性,铝股平均应力小于钢股平均应力,铝部和钢股应力比约为3∶7;外层和次外层铝合金股丝应力沿圆周向分布不均匀,建议大跨越导线线型设计时考虑铝股丝分层特性。

Thermo-hydro-poro-mechanical responses of a reservoir-induced landslide tracked by high-resolution fiber optic sensing nerves

Thermo-poro-mechanical responses along sliding zone/surface have been extensively studied.However,it has not been recognized that the potential contribution of other crucial engineering geological interfaces beyond the slip surface to progressive failure.Here,we aim to investigate the subsurface multiphysics of reservoir landslides under two extreme hydrologic conditions(i.e.wet and dry),particularly within sliding masses.Based on ultra-weak fiber Bragg grating(UWFBG)technology,we employ specialpurpose fiber optic sensing cables that can be implanted into boreholes as“nerves of the Earth”to collect data on soil temperature,water content,pore water pressure,and strain.The Xinpu landslide in the middle reach of the Three Gorges Reservoir Area in China was selected as a case study to establish a paradigm for in situ thermo-hydro-poro-mechanical monitoring.These UWFBG-based sensing cables were vertically buried in a 31 m-deep borehole at the foot of the landslide,with a resolution of 1 m except for the pressure sensor.We reported field measurements covering the period 2021 and 2022 and produced the spatiotemporal profiles throughout the borehole.Results show that wet years are more likely to motivate landslide motions than dry years.The annual thermally active layer of the landslide has a critical depth of roughly 9 m and might move downward in warmer years.The dynamic groundwater table is located at depths of 9e15 m,where the peaked strain undergoes a periodical response of leap and withdrawal to annual hydrometeorological cycles.These interface behaviors may support the interpretation of the contribution of reservoir regulation to slope stability,allowing us to correlate them to local damage events and potential global destabilization.This paper also offers a natural framework for interpreting thermo-hydro-poro-mechanical signatures from creeping reservoir bank slopes,which may form the basis for a landslide monitoring and early warning system.

基于超弱光纤光栅的声波传感探头增敏方法研究

针对光纤直接探测声波时灵敏度低的问题,提出一种超弱光纤光栅缠绕式薄壁圆筒的声波传感探头增敏方法。理论分析了薄壁圆筒半径、壁厚、弹性模量等参数对光纤探头声增敏的影响,仿真分析了光纤缠绕方式对探头谐振频率的影响,优化设计了弹性管式探头的结构。搭建了基于超弱光纤光栅声波传感系统,并对探头的声敏特性进行了测试。实验结果显示,探头的声压灵敏度最高可达到6.39746 rad/Pa(-103.8798 dB re rad/μPa),在1000~2000 Hz的平均声压灵敏度为3.30341 rad/Pa(-109.6208 dB re rad/μPa);相较于未增敏的裸光纤,探头的平均声压灵敏度提高了约31 dB。

Huge Capacity Fiber-Optic Sensing Network Based on Ultra-Weak Draw Tower Gratings

This paper reviews the work on huge capacity fiber-optic sensing network based on ultra-weak draw tower gratings developed at the National Engineering Laboratory for Fiber Optic Sensing Technology （NEL-FOST）, Wuhan University of Technology, China. A versatile drawing tower grating sensor network based on ultra-weak fiber Bragg gratings （FBGs） is firstly proposed and demonstrated. The sensing network is interrogated with time- and wavelength-division multiplexing method, which is very promising for the large-scale sensing network.

数值求解Helmholtz方程问题的超弱-傅里叶贝塞尔算法

应用超弱变分算法数值求解一类Helmholtz方程定解问题,算法使用傅里叶-贝塞尔函数进行逼近,改进了原有算法的数值模拟过程,使得数值计算过程更为简单,数值收敛速度更快,数值实验验证了算法的有效性。

Multi-Wavelength Ultra-Weak Fiber Bragg Grating Arrays for Long-Distance Quasi-Distributed Sensing

Fiber Bragg grating(FBG)array,consisting of a number of sensing units in a single optical fiber,can be practically applied in quasi-distributed sensing networks.Serious signal crosstalk occurring between large-serial of identical FBGs,however,has limited the further increase in the number of sensing units,thus restricting applications only for short-distance sensing networks.To reduce the signal crosstalk,we design two novel types of 10-kilometer-long FBG arrays with 10000 equally spaced gratings,written on-line using a customized grating inscription system,which is affiliated to a drawing tower.Main factors causing signal crosstalk,such as spectral shadowing and multiple reflections,are firstly investigated in theory.Consistent with the theoretical findings,experimental results are proving that ultra-weak(the reflectivity of—40 dB)and multi-wavelength gratings of a number more than 10000 can be readily identified,with satisfied low crosstalk.The maximum attenuation of grating signal and minimum signal-to-noise ratio(SNR)in a single-wavelength array are 10.69 dB and 5.62 dB,respectively.As a comparison,by increasing the number of central wavelengths to three,the attenuation can be effectively reduced to 5.54dB and the minimum SNR has been improved to 8.14 dB.The current study significantly enhances the multiplexing capacity of FBG arrays and demonstrates promising potentials for establishing large-capacity quasi-distributed sensing networks.

Ultra-weak bioluminescence and vigour of irradiated rice

Detection of the irradiation dose and the vigour of irradiated rice based on the ultra-weak luminescent analysis is one of the promising analytical detection methods.Rough rice and head rice flour were used in this research for ultra-weak luminescent analysis.The bioluminescence intensity of the rough rice was different at varying irradiation doses and storage time.The trend of the differences was consistent with the germination rates of the irradiated rough rice.The changes of the bioluminescence intensity and the germination rate of the irradiated rough rice at diverse irradiation doses and storage time were due to the damage to the rice embryo caused by irradiation and the self-repair function of the embryo during storage.As a result,the ultra-weak luminescent analysis cannot detect the dose of the irradiation treatment on rice,but it can be used to detect the vigour of the irradiated rice.Experimental results show that the irradiation dose has a highly significant effect on the bioluminescence intensity of the rough rice flour when sucrose was added.

基于超弱光纤布拉格光栅的声速测量方法

利用超弱光纤布拉格光栅对振动的敏感特性,提出了一种基于分布式光纤声学传感的声速测量方法。通过测量声速传递过程中不同超弱光纤布拉格光栅传感器接收到声音信号的时差来计算声速。该方法可以测量不同温度下的声速,其测量值与理论值误差小于0.5%。为声速测量提供了新的方法。

四阶线性方程极弱局部间断Galerkin法傅里叶分析

主要研究了四阶线性方程极弱局部间断Galerkin方法的傅里叶误差分析问题。首先,给出四阶线性方程的极弱局部间断Galerkin空间离散格式,并在周期边界条件及一致网格的条件下将离散格式表示为差分形式,然后,在k=2的情况下,利用傅里叶分析方法分析其稳定性及其误差估计问题,最后,利用数值实验,分别对得到的结果进行验证。

一次弱天气背景下浙江局地暖区暴雨成因分析

利用多源观测资料及ERA5(0.25°×0.25°)再分析资料,对2021年6月9日夜里浙江首场梅汛期局地暖区暴雨的降水成因进行了诊断分析。结果表明:此次过程环流形势与典型梅雨完全不同,属于弱天气背景下的局地暖区暴雨;南海低压和西太平洋副热带高压之间东南气流的维持,为暴雨区提供充沛的水汽来源,925 hPa超低空偏南风急流的加强有利于低层增温增湿,不稳定层结加剧,暴雨区位于急流轴左侧;整层高湿背景及较低的自由对流高度导致的弱抬升条件就能触发对流,中高层气旋性辐合旋转加强使暴雨加强,较厚的暖云层有利于提高降水效率;地面中尺度辐合带的生成激发了初始对流,其维持和加强不断激发对流云团生成,产生列车效应,导致暴雨形成。龙门山小尺度地形有利于东南气流在迎风坡强迫抬升,对流加强,且垂直速度的发展程度与地形有较好的对应关系,地形高度越高,激发的垂直速度越强。

基于四电平编码与弱光通信的极低功耗传光式电流互感器

针对传光式电流互感器高压侧现有的母线取能和激光供能方式存在供电死区、能量转换效率低、使用寿命不足等问题,提出一种基于四电平编码与弱光通信的极低功耗光电传输系统方案。首先,设计三态门电路将信号采集模块的采样时钟和数据信号叠加为一个四电平信号。然后,利用超高亮度且极低功耗的LED将四电平信号转换为光信号并通过光纤传输至低压侧。最后,在低压侧通过高灵敏度雪崩光电二极管探测器进行弱光检测后输入解码电路实现信号解码。将极低功耗光电传输系统应用于传光式电流互感器中进行实验验证,测量结果满足0.2级精度要求,系统高压侧的平均功耗可降低至3.91 mW,保证测量精度的同时大幅降低了功耗。由于高压侧的功耗极低,故可采用大容量电池或小功率光伏系统等可靠供能方案,从而解决了高压侧的供能问题,提高了系统的稳定性和可靠性。

超高比例新能源弱电网系统供电关键问题研究

随着电力系统中新能源并网规模快速增加,系统形态特征与运行机理发生深刻变化,特别对远离主网、缺乏传统能源的地区,面临电力保供和系统安全稳定等严峻挑战。现有研究多从源网荷储某一环节切入,提出中高比例新能源电力系统供电可靠性提升方法,缺乏对超高比例新能源弱电网系统特有难题的针对性考虑及系统性、前瞻性解决方案。为此,文中以新能源电量占比超过80%、新能源并网点短路比低于1.5的弱电网系统为研究对象,提出含电源及灵活调节资源优化配置、电网组网模式、暂态稳定运行分析的总体研究框架,并以我国西部某超高比例新能源弱电网系统为例开展实证研究。研究成果表明,所提方案以超高比例新能源发电为基础,以弱联电网为载体,以多元储能及负荷柔性调节为灵活性支撑,以构网控制技术为安全支撑,能有效保障系统可靠供电,为未来超高比例新能源新型电力系统的构建提供借鉴参考。

高密度电法在供电所地基塌陷沉降检测中的应用

某供电所地面发生塌陷沉降,导致墙体发生开裂,严重影响供电所的安全运行。为查明地面塌陷沉降诱发因素,根据地质调查,选取具有分辨率高、快速精准、异常响应特征明显的高密度电法作为无损检测方法,将其应用于地基沉降检测,通过常规高密度电法与超深高密度电法反演处理,并结合正演模拟对比分析。结果表明:高密度电法地电断面有效圈定了供电所底部软弱夹层,通过钻探进一步验证了物探解译成果的有效性,为查明供电所塌陷沉降诱发因素提供依据。

钻孔压灌桩的超弱光纤光栅应变场监测方法

提出了一种在长螺旋钻孔压灌桩中引入超弱光纤光栅的应变场监测方法。分析了超弱光纤光栅多点应变传感原理,设计了一种定点式标距1 m的超弱光纤光栅光缆,对灵敏度进行了标定,在10000με范围内的平均应变灵敏度为1.15 pm/με。在广州市有轨电车试验桩项目中,采用预拉力方式将光缆与钢筋笼结合后埋设,经过28天固化后对多根长螺旋钻孔压灌桩进行了静载测试和分析。试验表明,超弱光纤光栅传感系统工作频率1 Hz,应变精度1可实现对桩基应变场的多点、大量程、高精度的线性监测,验证了超弱光纤光栅传感器在桩基监测中的可行性。

Influence of high voltage static electric field on ultra-weak chemiluminescence of sheep semen

Ultra_weak chemiluminescence sent forth by animals’ organs, tissures and cell organs is discussed. It is indicated that if the ultra_weak chemiluminescence of an animal is high, its metabolism is exuberant, and its pregnant rate is high. A study of the influence of ligh voltage static electric field on the luminescence of sheep sperm is carried out.