Resilient TCP Variant Enabling Smooth Network Updates for Software-Defined Data Center Networks

Network updates have become increasingly prevalent since the broad adoption of software-defined networks(SDNs)in data centers.Modern TCP designs,including cutting-edge TCP variants DCTCP,CUBIC,and BBR,however,are not resilient to network updates that provoke flow rerouting.In this paper,we first demonstrate that popular TCP implementations perform inadequately in the presence of frequent and inconsistent network updates,because inconsistent and frequent network updates result in out-of-order packets and packet drops induced via transitory congestion and lead to serious performance deterioration.We look into the causes and propose a network update-friendly TCP(NUFTCP),which is an extension of the DCTCP variant,as a solution.Simulations are used to assess the proposed NUFTCP.Our findings reveal that NUFTCP can more effectively manage the problems of out-of-order packets and packet drops triggered in network updates,and it outperforms DCTCP considerably.

Fast Verification of Network Configuration Updates

With the expansion of network services,large-scale networks have progressively become common.The network status changes rapidly in response to customer needs and configuration changes,so network configuration changes are also very frequent.However,no matter what changes,the network must ensure the correct conditions,such as isolating tenants from each other or guaranteeing essential services.Once changes occur,it is necessary to verify the after-changed network.Whereas,for the verification of large-scale network configuration changes,many current verifiers show poor efficiency.In order to solve the problem ofmultiple global verifications caused by frequent updates of local configurations in large networks,we present a fast configuration updates verification tool,FastCUV,for distributed control planes.FastCUV aims to enhance the efficiency of distributed control plane verification for medium and large networks while ensuring correctness.This paper presents a method to determine the network range affected by the configuration change.We present a flow model and graph structure to facilitate the design of verification algorithms and speed up verification.Our scheme verifies the network area affected by obtaining the change of the Forwarding Information Base(FIB)before and after.FastCUV supports rich network attributes,meanwhile,has high efficiency and correctness performance.After experimental verification and result analysis,our method outperforms the state-of-the-art method to a certain extent.

Updates in the Diagnosis of Gestational Trophoblast Disease

GTD (Gestational Trophoblastic Disease) is a pathology that encompasses benign and malignant clinical forms, affects women of childbearing age, has a variable incidence and is more frequent in developing or underdeveloped countries, colliding with the economic barrier. The frequent absence of clear protocols and guidelines for the correct diagnosis of the pathology results in inadequate classification, imprecise treatment and failed post-therapeutic observation, increasing the risk of relapses, morbidity and mortality. The present study aims to point out updated national and international practice protocols of diagnosis of GTD, through an integrative review. Seven articles were selected and it was observed that the main international reference centers are agreed with the management suggested by the IFGO (International Federation of Gynecology and Obstetrics), being the conduct in the Hydatidiform Mole (HM): evacuation by suction and curettage under ultrasound guidance, followed by hCG monitoring every 1 - 2 weeks until normalized (usually one month for Partial Hydatidiform Mole six months for Complete Hydatidiform Mole and one year for Gestational Trophoblastic Neoplasia). Unfortunately, regarding the diagnosis of MH, the guidelines of some countries show the absence or difficulty of access to the karyotype test and ploid p57 or pelvic ultrasound accompanying the uterine curettage, contrary to what is proposed by the IFGO guideline. Establishing and complying with consistent guidelines can improve patient care, with early diagnosis of the pathology and its complications, reducing the rate of recurrence, morbidity and mortality, especially in less developed countries.

Use of Incremental Analysis Updates in 4D-Var Data Assimilation

The four-dimensional variational （4D-Var） data assimilation systems used in most operational and research centers use initial condition increments as control variables and adjust initial increments to find optimal analysis solutions. This approach may sometimes create discontinuities in analysis fields and produce undesirable spin ups and spin downs. This study explores using incremental analysis updates （IAU） in 4D-Var to reduce the analysis discontinuities. IAU-based 4D-Var has almost the same mathematical formula as conventional 4D-Var if the initial condition increments are replaced with time-integrated increments as control variables. The IAU technique was implemented in the NASA/GSFC 4D-Var prototype and compared against a control run without IAU. The results showed that the initial precipitation spikes were removed and that other discontinuities were also reduced, especially for the analysis of surface temperature.

Application of a Typhoon Initialization Scheme Based on the Incremental Analysis Updates Technique in a Rapid Update Cycle System

Initialization of tropical cyclones plays an important role in typhoon numerical prediction. This study applied a typhoon initialization scheme based on the incremental analysis updates (IAU) technique in a rapid refresh system to improve the prediction of Typhoon Lekima (2019). Two numerical sensitivity experiments with or without application of the IAU technique after performing vortex relocation and wind adjustment procedures were conducted for comparison with the control experiment, which did not involve a typhoon initialization scheme. Analysis of the initial fields indicated that the relocation procedure shifted the typhoon circulation to the observed typhoon region, and the wind speeds became closer to the observations following the wind adjustment procedure. Comparison of the results of the sensitivity and control experiments revealed that the vortex relocation and wind adjustment procedures could improve the prediction of typhoon track and intensity in the first 6-h period, and that these improvements were extended throughout the first 12-h period of the prediction by the IAU technique. The new typhoon initialization scheme also improved the simulated typhoon structure in terms of not only the wind speed and warm core prediction but also the organization of the eye of Typhoon Lekima. Diagnosis of the tendencies of variables showed that use of the IAU technique in a typhoon initialization scheme is efficacious in resolving the spurious high-frequency noise problem such that the model is able to reach equilibrium as soon as possible.

Updates of the NCCN guidelines for non-small cell lung cancer

Updates in version 2.2019 of the NCCN guidelines for non-small cell lung cancer from version 1.2019 NSCL-22 ALK rearrangement positive metastatic NSCLC:Lorlatinib added as a treatment option after progression on crizotinib and alectinib,brigatinib,or ceritinib.NSCL-23 ALK rearrangement positive metastatic NSCLC:Lorlatinib added as a treatment option,after progression on alectinib,brigatinib,or ceritinib.NSCL-24 ROS1 rearrangement positive metastatic NSCLC:Lorlatinib added as a treatment option,after progression on crizotinib or ceritinib.

Hypersphere support vector machines based on generalized multiplicative updates

This paper proposes a novel hypersphere support vector machines （HSVMs） based on generalized multiplicative updates. This algorithm can obtain the boundary of hypersphere containing one class of samples by the description of the training samples from one class and use this boundary to classify the test samples. The generalized multiplicative updates are applied to solving boundary optimization progranmning. Multiplicative updates available are suited for nonnegative quadratic convex programming. The generalized multiplicative updates are derived to box and sum constrained quadratic programming in this paper. They provide an extremely straightforward way to implement support vector machines （SVMs） where all variables are updated in parallel. The generalized multiplicative updates converge monotonically to the solution of the maximum margin hyperplane. The experiments show the superiority of our new algorithm.

Lawsuit Updates

Keda Elevator Company Infringes "KODAK" Trademark Right Ruling No. Suzhongminchuzi 0213/2005 The US Eastman Kodak began to use the "KODAK" as a trademark on camera in 1888, and it has, so far, registered nearly 1,700 "KODAK" trademarks in more than 150 countries and regions. From early 2005, the Keda Elevator Company (Keda for short) began to use the "KODAK" word only or together with "KEDA" in a top-down arrangement, on its lift and elevator products, its corporate signboard, its employees' name cards, ...

UPDATES

CPI Grew Slightly in January Consumer price index(CPI) growth in January of 2009 was 1.0 percent over the same period of the previous year.Of which,urban area and rural area up by 0.7 and 1.5 percent respectively;the price of foodstuff,consumable

UPDATES

Textile Exports may Drop Slightly in 2008The exports of China’s textile and garment will continue its double-digit growth in 2008, but with lower growth rate compared with 2007, according to Xu Kunyuan, the

UPDATES

China’s Inflation to Continue Easing in August China’s consumer price index (CPI), a key measure of inflation, was expected to show a rise of about 5 percent in August from a year earlier, said analysts on Thursday.

UPDATES

FDI Up by 23.58% in 2008 According to the statistics, from January to December 2008, foreign-invested enterprises newly approved for establishment reached

Computing the Moore-Penrose Inverse of a Matrix Through Symmetric Rank-One Updates

This paper presents a recursive procedure to compute the Moore-Penrose inverse of a matrix A. The method is based on the expression for the Moore-Penrose inverse of rank-one modified matrix. The computational complexity of the method is analyzed and a numerical example is included. A variant of the algorithm with lower computational complexity is also proposed. Both algorithms are tested on randomly generated matrices. Numerical performance confirms our theoretic results.

Journey of Immunohistochemistry in General and Oral Pathology:A Review on its Applications and Updates

Immunohistochemistry is a technique with an interesting journey.It is one of the well-established and reliable technique in modern pathology and it is extremely useful in diagnosis of sinister pathologies with perplexing histopathology.Not only does it enhance the diagnostic abilities of a pathologist,but it also has a huge prognostic potential,a great aid in establishing stage of malignancies,determines phenotypic expressions of lymphoid neoplasms and monitors treatment progress and response to therapy.By employing and integrating the basics of varied branches like immunology,histology,microscopy and hematology,it has emerged as a magnificent tool over last few decades,saving pathologists and patients from the impact of serious diseases inflicting the human body.Furthermore,it has contributed immensely to all aspects of diseases related to oral cavity as well.This review has been thus taken to highlight the wide applications of this technique in General and Oral Pathology with an update.

Free-walking:Pedestrian inertial navigation based on dual foot-mounted IMU

The inertial navigation system(INS),which is frequently used in emergency rescue operations and other situations,has the benefits of not relying on infrastructure,high positioning frequency,and strong real-time performance.However,the intricate and unpredictable pedestrian motion patterns lead the INS localization error to significantly diverge with time.This paper aims to enhance the accuracy of zero-velocity interval(ZVI)detection and reduce the heading and altitude drift of foot-mounted INS via deep learning and equation constraint of dual feet.Aiming at the observational noise problem of low-cost inertial sensors,we utilize a denoising autoencoder to automatically eliminate the inherent noise.Aiming at the problem that inaccurate detection of the ZVI detection results in obvious displacement error,we propose a sample-level ZVI detection algorithm based on the U-Net neural network,which effectively solves the problem of mislabeling caused by sliding windows.Aiming at the problem that Zero-Velocity Update(ZUPT)cannot suppress heading and altitude error,we propose a bipedal INS method based on the equation constraint and ellipsoid constraint,which uses foot-to-foot distance as a new observation to correct heading and altitude error.We conduct extensive and well-designed experiments to evaluate the performance of the proposed method.The experimental results indicate that the position error of our proposed method did not exceed 0.83% of the total traveled distance.

NON-QUASI-NEWTON UPDATES FOR UNCONSTRAINED OPTIMIZATION

In this report we present some new numerical methods for unconstrained optimization. These methods apply update formulae that do not satisfy the quasi-Newton equation. We derive these new formulae by considering different techniques of approximating the objective function. Theoretical analyses are given to show the advantages of using non-quasi-Newton updates. Under mild conditions we prove that our new update formulae preserve global convergence properties. Numerical results are also presented.

p53:updates on mechanisms,biology and therapy (Ⅱ)

In the second volume of this special issue, we focus on the activity and function of the mutant p53 proteins. The elegant work of Nakayama and Oshima (2019) uses mouse models of colorectal cancer to directly dem on strate the role that expression of the R273H protein has in promoting invasion. Using both animal studies and organotypic cultures, they are able to demonstrate that the gain-of-function (GOF) is driven by high-level nuclear expression of the protein and that this high-level expression requires escaping from Mdm2-depe ndent degradation and environ mental influe nee that are especially see n at the invadi ng front of the tumor. Their studies show that wildtype p53 can inhibit the GOF of the mutant protein providing clear support for the need for loss of the wild-type allele as the tumor progresses. This elegant in vivo work shows that the dominantnegative function of mutant p53 proteins has limited penetrance and helps to clarify this controversial area.

Dynamic Update Scheme of Spectrum Information Based on Spectrum Opportunity Incentive in the Database-Assisted Dynamic Spectrum Management

To solve the problem of delayed update of spectrum information(SI) in the database assisted dynamic spectrum management(DB-DSM), this paper studies a novel dynamic update scheme of SI in DB-DSM. Firstly, a dynamic update mechanism of SI based on spectrum opportunity incentive is established, in which spectrum users are encouraged to actively assist the database to update SI in real time. Secondly, the information update contribution(IUC) of spectrum opportunity is defined to describe the cost of accessing spectrum opportunity for heterogeneous spectrum users, and the profit of SI update obtained by the database from spectrum allocation. The process that the database determines the IUC of spectrum opportunity and spectrum user selects spectrum opportunity is mapped to a Hotelling model. Thirdly, the process of determining the IUC of spectrum opportunities is further modelled as a Stackelberg game by establishing multiple virtual spectrum resource providers(VSRPs) in the database. It is proved that there is a Nash Equilibrium in the game of determining the IUC of spectrum opportunities by VSRPs. Finally, an algorithm of determining the IUC based on a genetic algorithm is designed to achieve the optimal IUC. The-oretical analysis and simulation results show that the proposed method can quickly find the optimal solution of the IUC, and ensure that the spectrum resource provider can obtain the optimal profit of SI update.

An efficient physics-guided Bayesian framework for predicting ground settlement profile during excavations in clay

Recently,the application of Bayesian updating to predict excavation-induced deformation has proven successful and improved prediction accuracy significantly.However,updating the ground settlement profile,which is crucial for determining potential damage to nearby infrastructures,has received limited attention.To address this,this paper proposes a physics-guided simplified model combined with a Bayesian updating framework to accurately predict the ground settlement profile.The advantage of this model is that it eliminates the need for complex finite element modeling and makes the updating framework user-friendly.Furthermore,the model is physically interpretable,which can provide valuable references for construction adjustments.The effectiveness of the proposed method is demonstrated through two field case studies,showing that it can yield satisfactory predictions for the settlement profile.