Clinical Observation and Proposed Classification of Vitiliginous Patches by a Wood’s Lamp

Although vitiligo lesion especially in static state is characterized as sharply demarcated and complete depigmented macule, we encounter patients who have various manners of hypopigmented lesions. We examined the 81 lesions using the newly released Wood’s lamp (Woody®) and investigated whether or not vitiliginous lesions could be uniformly classified under Wood’s lamp illumination and also this classification helped to estimate the tendency of repigmentation after treatment. As result, the vitiliginous lesions were categorized into 4 types on intra- and peri-lesions prior to treatment by using the Wood’s lamp. The inside and border of the lesions were classified as follows: clear white, faint, multi-dot, and perifollicular for the inside, and sharp, blunt, confetti, and trichrome for the border. Suggestive residual pigmentation was detected in 73.6% of patients at the first visit and repigmentation was observed in 67.9% of patients at least 3 months after treatment. Lesions with the “clear white” inside pattern showed significantly lower repigmentation frequency in 38.5% of patients compared to others. The borders with 4 enlarged lesions were composed of 3 of confetti-type and one of sharp-type. This preliminary study demonstrated that detailed observation with a Wood’s lamp could be the basis to classify vitiliginous lesions and might be useful for predicting not only disease progression but also repigmentation prior to treatment.

The silent guardian of Chinese librarianship: Analysis on Miss Mary Elizabeth Wood’s will

Miss Mary Elizabeth Wood is the founder of Boone Library and Boone Library School.Her will is one of the most important documents in the history of Library Science in China,which is yet to be uncovered and discussed adequately.

Non-Invasive Evaluation and Differential Diagnosis for Pediatric Leukoderma in a Single Institute

Background: Although vitiligo shows a similar clinical picture to other disorders in which patients exhibit depigmented spots, there are few reports on the differentiation of these conditions from each other. Purpose: We aimed to investigate the differences and similarities between vitiligo and nevus depigmentosus in children based on the clinical course and characteristics. Materials and Methods: We conducted an examination of the disease type, treatment, progress, and differentiation of 85 cases of vitiligo and nevus depigmentosus that developed before 15 years of age among patients who visited the Osaka University Department of Dermatology with a chief complaint of white patches from January 2010 to March 2017. Results: The median age at the onset of symptoms of 79 patients with vitiligo was 4.5 years and while that of 6 patients with nevus depigmentosus was 0.8 years, indicating that the onset of nevus depigmentosus occurred earlier. While vitiligo often developed in the head and neck regions, with a tendency for depigmented spots in multiple regions, nevus depigmentosus did not show this tendency in these regions. Upon performing Wood’s lamp observation in 38 cases of vitiligo, 35 cases were found to be fluorescent chalky white and in 3 cases histologically diagnosed as vitiligo, no clear fluorescent color was observed. All 6 patients diagnosed with nevus depigmentosus exhibited a non-fluorescent off-white color under a Wood’s lamp. Conclusions: This study indicates that non-invasive observation using a Wood’s lamp is useful in the differential diagnosis of pediatric leukoderma, in addition to the subsequent clinical course, such as the presence or absence of lesional repigmentation and/or enlargement.

Extra-narrowband metallic filters with an ultrathin single-layer metallic grating

Narrowband and high-transmission optical filters are extensively used in color display technology, optical information processing, and high-sensitive sensing. Because of large ohmic losses in metallic nanostructures, metallic filters usually exhibit low transmittances and broad bandwidths. By employing both strong field enhancements in metallic nano-slits and the Wood’s anomaly in a periodic metallic grating, an extra-narrowband and high-transmission metallic filter is numerically predicted in an ultrathin single-layer metallic grating. Simulation results show that the Wood’s anomaly in the ultrathin(thickness H = 60 nm) single-layer metallic grating results in large field enhancements in the substrate and low losses in the metallic grating. As a result, the transmission bandwidth(transmittance T > 60%) at λ = 1200 nm is as small as △λFWHM=1.6 nm, which is smaller than 4% of that in the previous thin dielectric and metallic filters. The corresponding quality factor is as high as Q = λ/△λFWHM= 750, which is 40 times greater than that in the previous reports. Moreover, the thickness of our metallic filter(H = 60 nm) is smaller than 40% of that in the previous reports, and its maximum transmittance can reach up to 80%. In experiments, a narrowband metallic filter with a bandwidth of about △λFWHM = 10 nm, which is smaller than 25% of that in the previous metallic filters, is demonstrated.

一种适于基层部队应用的简易皮肤病检查装置

目的设计一种适于基层部队应用的简易皮肤病检查装置。方法简易皮肤病检测装置将两种不同放大倍数的放大镜和两种光线条件(白光灯和Wood’s灯)集于一体,并对126例疑似皮肤病患者进行检查。结果简易皮肤病检测装置使皮肤病的确诊率提高了21.42%,特别是对色素性皮肤病有较高的诊断价值。结论简易皮肤病检测装置能提高皮肤病的确诊率,具有携带方便、操作简便、安全可靠的特点,特别适合基层部队野战条件下使用,值得在基层部队推广应用。