The question of the impact of war on ecosystems still remains secondary in the internal and external policy of states, society and the agenda of international organizations. From the point of view of losses in monetar...The question of the impact of war on ecosystems still remains secondary in the internal and external policy of states, society and the agenda of international organizations. From the point of view of losses in monetary terms, the values of ecosystem damages obtained in the work, which are a consequence of the impact of hostilities on the environment, correspond to the annual budgets of the largest countries in the world or exceed them. The presented calculations significantly exceed the known normative methods, the use of which in the conditions of war is limited in space and time. Objective difficulties associated with the uncertainty of many processes of the development of ecological systems and their reaction to the multifactorial impact of war are also significant limitations. Therefore, as part of the study, a method of assessing the impact of war on the environment is proposed, which is based on the patterns of energy flows in ecosystems from the moment it is binding by producers. This made it possible to take into account in the calculations the principle of functional integrity of the ecological system, according to which the destruction or damage of the components of a functionally whole environment will necessarily cause negative phenomena in the development of ecological systems. The results are presented in the form of real values of ecological losses in energy and monetary equivalents, as consequences of the loss of ecosystem services. As the results of the research show, the minimum amount of damage to ecosystems from Russian tanks is 43,500 USD per day. Environmental damage from Russian fighter jets has been estimated at $1.5 billion per week since the start of the war. Noise from military operations causes losses of at least 2.3 billion US dollars per year. The obtained results create prerequisites for improving the system of ensuring environmental safety at the local, state, and international levels and transferring the obtained solutions into safety-shaping practice.展开更多
Background: Discharged against medical advice (DAMA) is defined as any instance when a patient wants to leave the hospital against the managing physician’s decision. This study aimed to identify factors that influenc...Background: Discharged against medical advice (DAMA) is defined as any instance when a patient wants to leave the hospital against the managing physician’s decision. This study aimed to identify factors that influence patients to decide to be DAMA. Methods: A descriptive, cross-sectional study. The study was conducted in the emergency department (ED) of King Fahad Medical City (KFMC)-Saudi Arabia-Riyadh city. A questionnaire in both Arabic and English was distributed to all participants to fill in either English or Arabic. Results: Between 1 March and 30 April 2021, 510 responses were collected. Most of the study participants (31.4%) were over the age of 54. Our findings showed that 12.5% of our participants had taken discharge against medical advice in the past. Results Regarding Factors That Influence Patients to Decide on DAMA Showed: Regarding Inappropriate behavior and disrespect of the physician or staff to the patient and his relatives, 262 (51.4%) participants, 85 (16.7%) participants, and 163 (32%) participants agreed, neutral, and disagreed, respectively. Regarding the Lack of physicians’ and nurses’ attention to the patient and his relatives (emotionally), our result showed that 278 (54.5%) participants, 95 (18.6%) participants, and 137 (26.9%) participants agreed, neutral, and disagree, respectively. Regarding failure to inform the patient or his relatives of his condition, it showed that 257 (50.4%) participants, 95 (18.6%) participants, and 158 (31%) participants agreed, neutral, and disagreed, respectively. Regarding feeling better from DAMA, our result showed 226 (44.3%) participants, 119 (23.3%) participants, and 165 (32.4%) participants agreed, neutral, and disagreed, respectively. Regarding patients’ or their relative’s tiredness of hospital stay, the result showed that 166 (32.5%) participants, 104 (20.4%) participants, and 240 (47.1%) participants agreed, neutral, and disagreed, respectively. Conclusion: The long wait time to be seen by a physician was the major factor that forced patients to leave the emergency department against medical advice.展开更多
Many clinicians would agree that a vegetative outcome is a fate worse than death after a severe traumatic brain injury (TBI). In an effort to avoid poor outcomes of this nature, neurotrauma practitioners draw from t...Many clinicians would agree that a vegetative outcome is a fate worse than death after a severe traumatic brain injury (TBI). In an effort to avoid poor outcomes of this nature, neurotrauma practitioners draw from their training and experience to make the monumental decision of when to recommend against aggressive care in severe TBI patients. Such judgements are,展开更多
A new isoflavone was obstained from the medicinal herb Amorpha fruticosa. It was elucidated asbenzopyran- 12-one, 1,4,10,11 - tetrahydro-6′-[8′-(hydroxymethy1)etheny1]-2,3-dimethoxy-8′-O-β-glucopyranosy1-O-α-D-...A new isoflavone was obstained from the medicinal herb Amorpha fruticosa. It was elucidated asbenzopyran- 12-one, 1,4,10,11 - tetrahydro-6′-[8′-(hydroxymethy1)etheny1]-2,3-dimethoxy-8′-O-β-glucopyranosy1-O-α-D-arabinoside by spectroscopic methods including UV, IR, 1D NMR and 2D NMR techniques. And the activity against acetaminophen-induced hepatotoxicity of this compound was also studied, and found this compound can protect liver obviously from hepatotoxicity induced by acetaminophen (AAP). ?2009 Ting Guo Kang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.展开更多
The present study considers a finite element analysis of elastic-plastic axi-symmetric hemispherical contact for a frictionless deformable sphere pressed by a rigid flat. The material of the sphere is modeled as elast...The present study considers a finite element analysis of elastic-plastic axi-symmetric hemispherical contact for a frictionless deformable sphere pressed by a rigid flat. The material of the sphere is modeled as elastic perfectly plastic. Analysis is carried out to study the effect of varying modulus of elasticity and sphere radius in wide range of dimensionless interference until the inception of plasticity as well as in plastic range. Results are compared with previous elastic-plastic models. It is found that materials with Young’s modulus to yield strength (E/Y) ratio less than and greater than 300 show strikingly different contact phenomena. The dependency of E on dimensionless interference at which the plastic region fully covers the surface is observed. However with different radius, finite element study exhibits similar elastic-plastic phenomena.展开更多
Aimed at eliminating all forms discrimination against women, ensuring human rights and fundamental freedoms for women in all fields and realizing de-facto equality between men and women, the Convention on the Eliminat...Aimed at eliminating all forms discrimination against women, ensuring human rights and fundamental freedoms for women in all fields and realizing de-facto equality between men and women, the Convention on the Elimination of All Forms of Discrimination Against Women adopted by the U.N. General Assembly is a most significant and most comprehensive legal document concerning the protection of human rights of women, which is called "The Charter of the Human Rights of Women." This thesis reviews the achievements and problems in the fulfillment by the Chinese government of obligations under the Convention after signing and ratifying it; and also puts forward some feasible approaches for improvement thereof.展开更多
A novel potassium complex KC9H9NO4SBr has been synthesized and characterized by IR spectra and single-crystal X-ray diffraction method. The crystal belongs to orthorhombic, space group Pbca with a = 0.74040(15), b =...A novel potassium complex KC9H9NO4SBr has been synthesized and characterized by IR spectra and single-crystal X-ray diffraction method. The crystal belongs to orthorhombic, space group Pbca with a = 0.74040(15), b = 0.74960(15), c = 4.2620(9) nm, V = 2.3654(8) nm^3, Mr = 346.24, Dc = 1.945 g/cm^3, Z = 8, F(000) = 1376, μ(MoKa) = 4.005mm^-1, GOOF = 1.021, R = 0.0471 and wR = 0.0872. In the crystal, the potassium ion is typically eight-coordinated, surrounded by eight O atoms from six (E)-2-(5-bromo-2-hydroxy-benzyli-deneamino)ethanesulfonate anions. The neighboring potassium ions are bridged by sulfonate groups into a two-dimensional layer structure, above and below which the 5-bromo-2-hydroxy-benzene rings are protruded. The activity against acetaminophen-induced hepatotoxicity of this complex was also studied, and found it can protect liver from hepatotoxicity induced by acetaminophen (AAP) to some extent.展开更多
The purpose of this study is to identify the main characteristics of violence against women in the context of a) intimate partner relationships and b) non-partner relationships in Mozambique, using the Revised Conflic...The purpose of this study is to identify the main characteristics of violence against women in the context of a) intimate partner relationships and b) non-partner relationships in Mozambique, using the Revised Conflict Tactics Scale (CTS2);measure the occurrence during lifetime or the past 12 months, and examine the association between intimate partner violence (IPV)/non-partner violence (NPV) types and predictor variables (demographic, socio-economic and lifestyle factors). A total of 1200 women (aged 15 - 45?years) were recruited to participate in this study. Results show that in Mozambique, generally, the rates of IPV and NPV are higher compared to those of other Sub-Saharan Africa countries (except when it comes to sexual assault). It seems that there is more violence against women within intimate partner relationship than in non-partner relationship. Adolescent, single young adults and women who experience the financial strain or use frequently alcohol are more vulnerable to be abused.展开更多
In Portugal, over the last 20 years, we have seen great strides in addressing intimate partner violence against women by their male partners. Measuring and understanding progress, and achieving sustainable systems cha...In Portugal, over the last 20 years, we have seen great strides in addressing intimate partner violence against women by their male partners. Measuring and understanding progress, and achieving sustainable systems change is a major challenge and to achieve this aim we need to identify events, persons and settings that contribute for the critical factors that create long term transformations in the systems and the creation of new resources [1]. Since the healthcare system is one of the main actors of intervention with survivors, the goal of this project was to interview key stakeholders from the healthcare system in order to understand the main changes they perceive have happened over the past two decades. Based on interviews with key stakeholders, our study explores the evidences of the changes that occurred in the healthcare system, the intersections with other systems and their visions for the future.展开更多
A chloro-bridged dinuclear copper(H) complex with ligand 2-pyridylme-thylene- furfurylamine has been synthesized and characterized by single-crystal X-ray diffraction, and its inhibitory activity on xanthine oxidase...A chloro-bridged dinuclear copper(H) complex with ligand 2-pyridylme-thylene- furfurylamine has been synthesized and characterized by single-crystal X-ray diffraction, and its inhibitory activity on xanthine oxidase (XO) was also evaluated. It crystallizes in the triclinic system, space group P 1 with a = 8.0441(16), b = 8.5663(17), c = 10.060(2)A, α = 77.52(3), β = 72.04(3), γ = 70.12(3)°, V = 615.3(2)A^3, Z = 1, Dc = 1.731 g/cm^3, F(000) = 322, the final R = 0.0401 and wR = 0.0934 for 1971 observed reflections with I 〉 2σ(I). X-ray analysis reveals that the Cu(II) cation is five-coordinated by two N atoms of Schiff base and three Cl anions. The C-H…Cl intermolecular and intramolecular hydrogen bonds connect the molecules to form a three-dimensional network. This copper(II) complex shows more potent inhibitory activity against XO with IC50 = 3.48μM than the standard inhibitor allopurinol.展开更多
The single chain variable fragments of antibodies(scFvs) against cTnI were screened from the phage display antibody library by using cTnI as the target antigen. After four rounds of panning, four clones(H2, G5, A9, B9...The single chain variable fragments of antibodies(scFvs) against cTnI were screened from the phage display antibody library by using cTnI as the target antigen. After four rounds of panning, four clones(H2, G5, A9, B9) from the phage display antibody library were verified to show higher binding affinity for cTnI by ELISA and to contain the variable region genes of the light and heavy chains of scFvs by sequencing. The variable region genes of scFvs H2 and G5 were successfully amplified by polymerase chain reactions(PCR) and cloned into expression vector pPELB and expressed as a soluble protein in E.coli Rosetta, whose expression yield was about 2% of total proteins. The expressed proteins were purified by nickel(Ni) affinity chromatography and a single band is shown in the position of 28 kDa on SDS-PAGE. The western blot analysis result verifies that the expressed scFv proteins are capable of binding with monoclonal antibodies against hexa-histidine, indicating that they are hexa-histidin-tagged aim proteins. The immunoassay demonstrates that the expressed scFv proteins are able to specifically react with cTnI molecules. The association constant(K_A) values range from 1.2×10 4 to 1.7 ×10 5 L/mol that are correspondent to the affinities of polyclonal antibodies against cTnI from rabbits. These antibodies can be valuable reagents for the immunoassay of cTnI.展开更多
[ Objective] To study the correlation between HI titer and protection against IBV challenge in SPF layers. [ Method ] SPF layers were randomly divided into four groups, namely group A1, A2, B1 and B2. The group A1 was...[ Objective] To study the correlation between HI titer and protection against IBV challenge in SPF layers. [ Method ] SPF layers were randomly divided into four groups, namely group A1, A2, B1 and B2. The group A1 was immunized with H120 live vaccine. The group A2 was first immunized with H120 live vaccine and later boosted with ND-IB-EDS trivalent inactivated vaccine. The group B1 was used as unimmunized chal- lenge control. The group B2 was kept as unimmunized unchallenged control. The blood samples were taken prior and post-vaccination at intervals and HI tests were conducted. At the laying peak, the group A1, A2 and B1 were challenged with IBV M4t virulent strain. The clinical features and egg production of layers were monitored and recorded. [Result] After 30 d post vaccination with H120 live vaccine, the HI titer reached 4.45 log2; after 30 days boosting with ND-IB-EDS trivalent inactivated vaccine, the HI titer reached to 7.35 log2. Before challenge, HI antibody titer in group A1, A2, B1 and B2 were respectively 4.24 log2, 7.40 Iog2, 2.10 log2 and 2.10 log2. After challenge, chickens in unimmunized challenge control group B1 showed respiratory symptoms, egg production dropped by 30.9%, and they produced more soft-shelled, no-shelled or abnormal eggs. In the group A1, some chickens had light respiratory symptoms and egg production dropped by 11.7%. In the group A2, the egg production of all chickens was as normal as the group B2. [ Conclusion] When the HI titer was over 6 log2, challenge by virulent virus had no impact on egg produc- tion; when the HI titer was 5 log2, 4 log2 and less 3 log2, egg production dropped by 6.0%, 11.3% and 29.6%, respectively. Thus, the HI anti- body level in chickens has close correlation with protection against IBV challenge.展开更多
For meeting the need of rapid development of economy in Shanghai and the protection against earthquake and disaster reduction in the mega city, it is necessary to build a information system for emergence decision on t...For meeting the need of rapid development of economy in Shanghai and the protection against earthquake and disaster reduction in the mega city, it is necessary to build a information system for emergence decision on the protection against earthquake and disaster reduction in the city. In this paper, GIS is applied to 'the information system for emergence decision on the protection against earthquake and disaster reduction in Shanghai City (Baoshan experiment region)'. We introduce to the structure and effect of each functional module in this information system. This information system consists of 7 functional modules:background information of seismology and geology, subsystem for rapid evaluation of damage loss from earthquake, subsystem for the decisive information on earthquake emergence, information query, maintenance and management of system, help, quit. The key parts of this information system are the subsystem for rapid evaluation of damage loss from earthquake and the subsystem for the decisive information on earthquake emergence. Also, this paper introduces to the application of technology of color infra-red aerial photograph remote sensing to this information system.展开更多
Twenty patients with chronic hepatitis c were investigated during the treatment with interferon to explore the changes of antibodies to HCV (anti-RCV). Anti-HCV was tested with recombinant immunoblot assay (RIBA) by u...Twenty patients with chronic hepatitis c were investigated during the treatment with interferon to explore the changes of antibodies to HCV (anti-RCV). Anti-HCV was tested with recombinant immunoblot assay (RIBA) by using three antigens (C22, C33c, and C100-3) encoded by different regions of HCV genome. The changes of individual anti-HCV and ALT were compared with the change of HCV RNA. The results showed that persistent disappearance of serum HCV RNA was closely related to the changes of anti-C33c (P<0. 01) and anti-C100-3 (P<0. 005), but there was no relation between persistent ALT normality and HCV viremia clearance (P<0. 05). In conclusion, monitoring anti-C33c and anti-C100-3 could indicate the changes or HCV viremia. The normalization of ALT after interferon treatment did not indicate disappearance of HCV viremia.展开更多
The RE-Fe-B permanent magnets have a complex microstructure and they are susceptible to corrosion process. In this paper, the commercial nickel coatings adhesion was investigated. The microstructure of the RE-Fe-B wit...The RE-Fe-B permanent magnets have a complex microstructure and they are susceptible to corrosion process. In this paper, the commercial nickel coatings adhesion was investigated. The microstructure of the RE-Fe-B without coating was analyzed by scanning electronic microscopy and electrochemical techniques. The interface magnet/coating was studied by scanning electron microscopy and the nickel-plated Nd-Fe-B commercial magnets were tested in a salt spray chamber. The ferromagnetic and RE-rich phases were observed. After the anodic polarization curve, a strong intergranular corrosion was observed and the RE-rich phase was preferentially attacked. The interface magnet/Ni coating presented inter-granular corrosion that can affect the nickel coating adherence. This attack had probably occurred during the electrodeposition process. Not all the samples suffered localized corrosion during the salt spray tests and the Ni triple-layer coating presented a few corrosion points. RE-Fe-B alloy magnets need to be protected with appropriate coatings to each environment to which they will be exposed and the protective coating must not be damaged.展开更多
<b><span style="font-family:Verdana;">Introduction:</span></b><span><span><span style="font-family:;" "=""><span style="font-family:...<b><span style="font-family:Verdana;">Introduction:</span></b><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;"> Binding retains an important place in Africa. Leaving a health facility to see a bonesetter is common there, but a source of complications. The purpose of this work was to analyze the results obtained by bonesetter </span><span><span style="font-family:Verdana;">after discharge against medical advice. </span><b><span style="font-family:Verdana;">Methodology:</span></b><span style="font-family:Verdana;"> Analytical cross-sectional</span></span><span style="font-family:Verdana;"> study over a period of one year, including all patients admitted for limb fracture, discharged against medical advice for treatment with a bonesetter. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> Thirty-nine patients were selected. The average age was 36.9 years, and the sex ratio was 5.50. The fractures were open in 35.9%. At a mean follow-up of 19 months, the course was marked by pain in 34.4% and inequality in limb length in 62.5%. Thirteen fractures (40.6%) were consolidated with axis defect, and 11 were without axis defect (34.4%). There were eight non-union (25%), and eleven patients (34.4%) presented with stiffness in one or more joints. Seven patients had died. </span><b><span style="font-family:Verdana;">Discussion:</span></b><span style="font-family:Verdana;"> The problem of discharge against medical advice is found in all hospitals but is particularly marked for fractures in our context. The absence of an X-ray and ignorance of the rules of asepsis lead to complications. Only the fractures of the two bones of the leg had progressed well (5/8 good results). The rate of vicious calluses (40.6%) and non-union (25%) is high. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> Although a few cases have progressed favorably, the results of patients traditionally treated after discharge against medical advice are generally poor.</span></span></span></span>展开更多
The paper describes a GIS approach to identify the most suitable areas for growing the Paulownia tree in the Province of Bergamo;this work will become the subject of a dissertation thesis at the School of Engineering ...The paper describes a GIS approach to identify the most suitable areas for growing the Paulownia tree in the Province of Bergamo;this work will become the subject of a dissertation thesis at the School of Engineering of the University of Bergamo. Paulownia is quite an ancient tree, well known especially in the far east countries, for its wonderful flowers and the quality of the wood which is a source of certain profit. The paper is focused on the employment of the Paulownia tree against air pollution, since its big leaves absorb high amounts of CO2 in the atmosphere and can capture the small particles of pollutants in the air ten times more than any other tree species. First, the analysis identifies the most favourable areas for its growth in the Province of Bergamo. Secondly, among the latter, the analysis detects the strategic areas for its growth near the most polluted zones. Finally, a quantitative evaluation is carried out about the trees contribution against pollutants in the atmosphere.展开更多
The present demographic scenario of the country shows the rising trend of adult population. According to census report 2011, there are 60.3% people belonging to 15 to 59 years of age group and the percentage of people...The present demographic scenario of the country shows the rising trend of adult population. According to census report 2011, there are 60.3% people belonging to 15 to 59 years of age group and the percentage of people above 60+ age is 8.6%. Our country fails to provide due respect, care, affection, security and health related facilities, which elderly people utmost require. A number of cases of adult abuses are reported in news papers as these people are easy victims of violence and criminal activities. The society comes to know about only those problems, which are reported, the innumerable cases of disrespect and neglect are not given any consideration. The situation becomes all the more worst when perpetrators are very near relatives and in some cases blood relatives also. This growing insensitiveness is a threat to our society. Sincere efforts are needed to tackle this alarming problem. The present paper describes the available data [1]-[3] on the old people, their dependence ratio, the problems being faced by them and suggestive measures to provide social and emotional security to them.展开更多
文摘The question of the impact of war on ecosystems still remains secondary in the internal and external policy of states, society and the agenda of international organizations. From the point of view of losses in monetary terms, the values of ecosystem damages obtained in the work, which are a consequence of the impact of hostilities on the environment, correspond to the annual budgets of the largest countries in the world or exceed them. The presented calculations significantly exceed the known normative methods, the use of which in the conditions of war is limited in space and time. Objective difficulties associated with the uncertainty of many processes of the development of ecological systems and their reaction to the multifactorial impact of war are also significant limitations. Therefore, as part of the study, a method of assessing the impact of war on the environment is proposed, which is based on the patterns of energy flows in ecosystems from the moment it is binding by producers. This made it possible to take into account in the calculations the principle of functional integrity of the ecological system, according to which the destruction or damage of the components of a functionally whole environment will necessarily cause negative phenomena in the development of ecological systems. The results are presented in the form of real values of ecological losses in energy and monetary equivalents, as consequences of the loss of ecosystem services. As the results of the research show, the minimum amount of damage to ecosystems from Russian tanks is 43,500 USD per day. Environmental damage from Russian fighter jets has been estimated at $1.5 billion per week since the start of the war. Noise from military operations causes losses of at least 2.3 billion US dollars per year. The obtained results create prerequisites for improving the system of ensuring environmental safety at the local, state, and international levels and transferring the obtained solutions into safety-shaping practice.
文摘Background: Discharged against medical advice (DAMA) is defined as any instance when a patient wants to leave the hospital against the managing physician’s decision. This study aimed to identify factors that influence patients to decide to be DAMA. Methods: A descriptive, cross-sectional study. The study was conducted in the emergency department (ED) of King Fahad Medical City (KFMC)-Saudi Arabia-Riyadh city. A questionnaire in both Arabic and English was distributed to all participants to fill in either English or Arabic. Results: Between 1 March and 30 April 2021, 510 responses were collected. Most of the study participants (31.4%) were over the age of 54. Our findings showed that 12.5% of our participants had taken discharge against medical advice in the past. Results Regarding Factors That Influence Patients to Decide on DAMA Showed: Regarding Inappropriate behavior and disrespect of the physician or staff to the patient and his relatives, 262 (51.4%) participants, 85 (16.7%) participants, and 163 (32%) participants agreed, neutral, and disagreed, respectively. Regarding the Lack of physicians’ and nurses’ attention to the patient and his relatives (emotionally), our result showed that 278 (54.5%) participants, 95 (18.6%) participants, and 137 (26.9%) participants agreed, neutral, and disagree, respectively. Regarding failure to inform the patient or his relatives of his condition, it showed that 257 (50.4%) participants, 95 (18.6%) participants, and 158 (31%) participants agreed, neutral, and disagreed, respectively. Regarding feeling better from DAMA, our result showed 226 (44.3%) participants, 119 (23.3%) participants, and 165 (32.4%) participants agreed, neutral, and disagreed, respectively. Regarding patients’ or their relative’s tiredness of hospital stay, the result showed that 166 (32.5%) participants, 104 (20.4%) participants, and 240 (47.1%) participants agreed, neutral, and disagreed, respectively. Conclusion: The long wait time to be seen by a physician was the major factor that forced patients to leave the emergency department against medical advice.
文摘Many clinicians would agree that a vegetative outcome is a fate worse than death after a severe traumatic brain injury (TBI). In an effort to avoid poor outcomes of this nature, neurotrauma practitioners draw from their training and experience to make the monumental decision of when to recommend against aggressive care in severe TBI patients. Such judgements are,
基金supported by the Science and Technology of Dalian(No.2008E11SF168).
文摘A new isoflavone was obstained from the medicinal herb Amorpha fruticosa. It was elucidated asbenzopyran- 12-one, 1,4,10,11 - tetrahydro-6′-[8′-(hydroxymethy1)etheny1]-2,3-dimethoxy-8′-O-β-glucopyranosy1-O-α-D-arabinoside by spectroscopic methods including UV, IR, 1D NMR and 2D NMR techniques. And the activity against acetaminophen-induced hepatotoxicity of this compound was also studied, and found this compound can protect liver obviously from hepatotoxicity induced by acetaminophen (AAP). ?2009 Ting Guo Kang. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
文摘The present study considers a finite element analysis of elastic-plastic axi-symmetric hemispherical contact for a frictionless deformable sphere pressed by a rigid flat. The material of the sphere is modeled as elastic perfectly plastic. Analysis is carried out to study the effect of varying modulus of elasticity and sphere radius in wide range of dimensionless interference until the inception of plasticity as well as in plastic range. Results are compared with previous elastic-plastic models. It is found that materials with Young’s modulus to yield strength (E/Y) ratio less than and greater than 300 show strikingly different contact phenomena. The dependency of E on dimensionless interference at which the plastic region fully covers the surface is observed. However with different radius, finite element study exhibits similar elastic-plastic phenomena.
文摘Aimed at eliminating all forms discrimination against women, ensuring human rights and fundamental freedoms for women in all fields and realizing de-facto equality between men and women, the Convention on the Elimination of All Forms of Discrimination Against Women adopted by the U.N. General Assembly is a most significant and most comprehensive legal document concerning the protection of human rights of women, which is called "The Charter of the Human Rights of Women." This thesis reviews the achievements and problems in the fulfillment by the Chinese government of obligations under the Convention after signing and ratifying it; and also puts forward some feasible approaches for improvement thereof.
基金supported by the Science and Technology of Dalian (No. 2008E11SF168)
文摘A novel potassium complex KC9H9NO4SBr has been synthesized and characterized by IR spectra and single-crystal X-ray diffraction method. The crystal belongs to orthorhombic, space group Pbca with a = 0.74040(15), b = 0.74960(15), c = 4.2620(9) nm, V = 2.3654(8) nm^3, Mr = 346.24, Dc = 1.945 g/cm^3, Z = 8, F(000) = 1376, μ(MoKa) = 4.005mm^-1, GOOF = 1.021, R = 0.0471 and wR = 0.0872. In the crystal, the potassium ion is typically eight-coordinated, surrounded by eight O atoms from six (E)-2-(5-bromo-2-hydroxy-benzyli-deneamino)ethanesulfonate anions. The neighboring potassium ions are bridged by sulfonate groups into a two-dimensional layer structure, above and below which the 5-bromo-2-hydroxy-benzene rings are protruded. The activity against acetaminophen-induced hepatotoxicity of this complex was also studied, and found it can protect liver from hepatotoxicity induced by acetaminophen (AAP) to some extent.
文摘The purpose of this study is to identify the main characteristics of violence against women in the context of a) intimate partner relationships and b) non-partner relationships in Mozambique, using the Revised Conflict Tactics Scale (CTS2);measure the occurrence during lifetime or the past 12 months, and examine the association between intimate partner violence (IPV)/non-partner violence (NPV) types and predictor variables (demographic, socio-economic and lifestyle factors). A total of 1200 women (aged 15 - 45?years) were recruited to participate in this study. Results show that in Mozambique, generally, the rates of IPV and NPV are higher compared to those of other Sub-Saharan Africa countries (except when it comes to sexual assault). It seems that there is more violence against women within intimate partner relationship than in non-partner relationship. Adolescent, single young adults and women who experience the financial strain or use frequently alcohol are more vulnerable to be abused.
文摘In Portugal, over the last 20 years, we have seen great strides in addressing intimate partner violence against women by their male partners. Measuring and understanding progress, and achieving sustainable systems change is a major challenge and to achieve this aim we need to identify events, persons and settings that contribute for the critical factors that create long term transformations in the systems and the creation of new resources [1]. Since the healthcare system is one of the main actors of intervention with survivors, the goal of this project was to interview key stakeholders from the healthcare system in order to understand the main changes they perceive have happened over the past two decades. Based on interviews with key stakeholders, our study explores the evidences of the changes that occurred in the healthcare system, the intersections with other systems and their visions for the future.
基金the National Natural Science Foundation of China (No. 649620)
文摘A chloro-bridged dinuclear copper(H) complex with ligand 2-pyridylme-thylene- furfurylamine has been synthesized and characterized by single-crystal X-ray diffraction, and its inhibitory activity on xanthine oxidase (XO) was also evaluated. It crystallizes in the triclinic system, space group P 1 with a = 8.0441(16), b = 8.5663(17), c = 10.060(2)A, α = 77.52(3), β = 72.04(3), γ = 70.12(3)°, V = 615.3(2)A^3, Z = 1, Dc = 1.731 g/cm^3, F(000) = 322, the final R = 0.0401 and wR = 0.0934 for 1971 observed reflections with I 〉 2σ(I). X-ray analysis reveals that the Cu(II) cation is five-coordinated by two N atoms of Schiff base and three Cl anions. The C-H…Cl intermolecular and intramolecular hydrogen bonds connect the molecules to form a three-dimensional network. This copper(II) complex shows more potent inhibitory activity against XO with IC50 = 3.48μM than the standard inhibitor allopurinol.
文摘The single chain variable fragments of antibodies(scFvs) against cTnI were screened from the phage display antibody library by using cTnI as the target antigen. After four rounds of panning, four clones(H2, G5, A9, B9) from the phage display antibody library were verified to show higher binding affinity for cTnI by ELISA and to contain the variable region genes of the light and heavy chains of scFvs by sequencing. The variable region genes of scFvs H2 and G5 were successfully amplified by polymerase chain reactions(PCR) and cloned into expression vector pPELB and expressed as a soluble protein in E.coli Rosetta, whose expression yield was about 2% of total proteins. The expressed proteins were purified by nickel(Ni) affinity chromatography and a single band is shown in the position of 28 kDa on SDS-PAGE. The western blot analysis result verifies that the expressed scFv proteins are capable of binding with monoclonal antibodies against hexa-histidine, indicating that they are hexa-histidin-tagged aim proteins. The immunoassay demonstrates that the expressed scFv proteins are able to specifically react with cTnI molecules. The association constant(K_A) values range from 1.2×10 4 to 1.7 ×10 5 L/mol that are correspondent to the affinities of polyclonal antibodies against cTnI from rabbits. These antibodies can be valuable reagents for the immunoassay of cTnI.
文摘[ Objective] To study the correlation between HI titer and protection against IBV challenge in SPF layers. [ Method ] SPF layers were randomly divided into four groups, namely group A1, A2, B1 and B2. The group A1 was immunized with H120 live vaccine. The group A2 was first immunized with H120 live vaccine and later boosted with ND-IB-EDS trivalent inactivated vaccine. The group B1 was used as unimmunized chal- lenge control. The group B2 was kept as unimmunized unchallenged control. The blood samples were taken prior and post-vaccination at intervals and HI tests were conducted. At the laying peak, the group A1, A2 and B1 were challenged with IBV M4t virulent strain. The clinical features and egg production of layers were monitored and recorded. [Result] After 30 d post vaccination with H120 live vaccine, the HI titer reached 4.45 log2; after 30 days boosting with ND-IB-EDS trivalent inactivated vaccine, the HI titer reached to 7.35 log2. Before challenge, HI antibody titer in group A1, A2, B1 and B2 were respectively 4.24 log2, 7.40 Iog2, 2.10 log2 and 2.10 log2. After challenge, chickens in unimmunized challenge control group B1 showed respiratory symptoms, egg production dropped by 30.9%, and they produced more soft-shelled, no-shelled or abnormal eggs. In the group A1, some chickens had light respiratory symptoms and egg production dropped by 11.7%. In the group A2, the egg production of all chickens was as normal as the group B2. [ Conclusion] When the HI titer was over 6 log2, challenge by virulent virus had no impact on egg produc- tion; when the HI titer was 5 log2, 4 log2 and less 3 log2, egg production dropped by 6.0%, 11.3% and 29.6%, respectively. Thus, the HI anti- body level in chickens has close correlation with protection against IBV challenge.
基金Science and Technology Development Fund Item of Shanghai !(962512006).
文摘For meeting the need of rapid development of economy in Shanghai and the protection against earthquake and disaster reduction in the mega city, it is necessary to build a information system for emergence decision on the protection against earthquake and disaster reduction in the city. In this paper, GIS is applied to 'the information system for emergence decision on the protection against earthquake and disaster reduction in Shanghai City (Baoshan experiment region)'. We introduce to the structure and effect of each functional module in this information system. This information system consists of 7 functional modules:background information of seismology and geology, subsystem for rapid evaluation of damage loss from earthquake, subsystem for the decisive information on earthquake emergence, information query, maintenance and management of system, help, quit. The key parts of this information system are the subsystem for rapid evaluation of damage loss from earthquake and the subsystem for the decisive information on earthquake emergence. Also, this paper introduces to the application of technology of color infra-red aerial photograph remote sensing to this information system.
文摘Twenty patients with chronic hepatitis c were investigated during the treatment with interferon to explore the changes of antibodies to HCV (anti-RCV). Anti-HCV was tested with recombinant immunoblot assay (RIBA) by using three antigens (C22, C33c, and C100-3) encoded by different regions of HCV genome. The changes of individual anti-HCV and ALT were compared with the change of HCV RNA. The results showed that persistent disappearance of serum HCV RNA was closely related to the changes of anti-C33c (P<0. 01) and anti-C100-3 (P<0. 005), but there was no relation between persistent ALT normality and HCV viremia clearance (P<0. 05). In conclusion, monitoring anti-C33c and anti-C100-3 could indicate the changes or HCV viremia. The normalization of ALT after interferon treatment did not indicate disappearance of HCV viremia.
文摘The RE-Fe-B permanent magnets have a complex microstructure and they are susceptible to corrosion process. In this paper, the commercial nickel coatings adhesion was investigated. The microstructure of the RE-Fe-B without coating was analyzed by scanning electronic microscopy and electrochemical techniques. The interface magnet/coating was studied by scanning electron microscopy and the nickel-plated Nd-Fe-B commercial magnets were tested in a salt spray chamber. The ferromagnetic and RE-rich phases were observed. After the anodic polarization curve, a strong intergranular corrosion was observed and the RE-rich phase was preferentially attacked. The interface magnet/Ni coating presented inter-granular corrosion that can affect the nickel coating adherence. This attack had probably occurred during the electrodeposition process. Not all the samples suffered localized corrosion during the salt spray tests and the Ni triple-layer coating presented a few corrosion points. RE-Fe-B alloy magnets need to be protected with appropriate coatings to each environment to which they will be exposed and the protective coating must not be damaged.
文摘<b><span style="font-family:Verdana;">Introduction:</span></b><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;"> Binding retains an important place in Africa. Leaving a health facility to see a bonesetter is common there, but a source of complications. The purpose of this work was to analyze the results obtained by bonesetter </span><span><span style="font-family:Verdana;">after discharge against medical advice. </span><b><span style="font-family:Verdana;">Methodology:</span></b><span style="font-family:Verdana;"> Analytical cross-sectional</span></span><span style="font-family:Verdana;"> study over a period of one year, including all patients admitted for limb fracture, discharged against medical advice for treatment with a bonesetter. </span><b><span style="font-family:Verdana;">Results:</span></b><span style="font-family:Verdana;"> Thirty-nine patients were selected. The average age was 36.9 years, and the sex ratio was 5.50. The fractures were open in 35.9%. At a mean follow-up of 19 months, the course was marked by pain in 34.4% and inequality in limb length in 62.5%. Thirteen fractures (40.6%) were consolidated with axis defect, and 11 were without axis defect (34.4%). There were eight non-union (25%), and eleven patients (34.4%) presented with stiffness in one or more joints. Seven patients had died. </span><b><span style="font-family:Verdana;">Discussion:</span></b><span style="font-family:Verdana;"> The problem of discharge against medical advice is found in all hospitals but is particularly marked for fractures in our context. The absence of an X-ray and ignorance of the rules of asepsis lead to complications. Only the fractures of the two bones of the leg had progressed well (5/8 good results). The rate of vicious calluses (40.6%) and non-union (25%) is high. </span><b><span style="font-family:Verdana;">Conclusion:</span></b><span style="font-family:Verdana;"> Although a few cases have progressed favorably, the results of patients traditionally treated after discharge against medical advice are generally poor.</span></span></span></span>
文摘The paper describes a GIS approach to identify the most suitable areas for growing the Paulownia tree in the Province of Bergamo;this work will become the subject of a dissertation thesis at the School of Engineering of the University of Bergamo. Paulownia is quite an ancient tree, well known especially in the far east countries, for its wonderful flowers and the quality of the wood which is a source of certain profit. The paper is focused on the employment of the Paulownia tree against air pollution, since its big leaves absorb high amounts of CO2 in the atmosphere and can capture the small particles of pollutants in the air ten times more than any other tree species. First, the analysis identifies the most favourable areas for its growth in the Province of Bergamo. Secondly, among the latter, the analysis detects the strategic areas for its growth near the most polluted zones. Finally, a quantitative evaluation is carried out about the trees contribution against pollutants in the atmosphere.
文摘The present demographic scenario of the country shows the rising trend of adult population. According to census report 2011, there are 60.3% people belonging to 15 to 59 years of age group and the percentage of people above 60+ age is 8.6%. Our country fails to provide due respect, care, affection, security and health related facilities, which elderly people utmost require. A number of cases of adult abuses are reported in news papers as these people are easy victims of violence and criminal activities. The society comes to know about only those problems, which are reported, the innumerable cases of disrespect and neglect are not given any consideration. The situation becomes all the more worst when perpetrators are very near relatives and in some cases blood relatives also. This growing insensitiveness is a threat to our society. Sincere efforts are needed to tackle this alarming problem. The present paper describes the available data [1]-[3] on the old people, their dependence ratio, the problems being faced by them and suggestive measures to provide social and emotional security to them.