期刊文献+
共找到230篇文章
< 1 2 12 >
每页显示 20 50 100
Phosphotungstic acid immobilized on amino-functionalized TS-1 zeolite as a solid acid catalyst for the synthesis of tributyl citrate
1
作者 Pei Li Bianfang Shi +4 位作者 Junyao Shen Ran Cui Wenze Guo Ling Zhao Zhenhao Xi 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2024年第6期199-210,共12页
The amino-functionalization of TS-1 zeolite followed by immobilization of phosphotungstic acid(HPW)was presented to prepare a strong solid acid catalyst for the synthesis of bio-based tributyl citrate from the esterif... The amino-functionalization of TS-1 zeolite followed by immobilization of phosphotungstic acid(HPW)was presented to prepare a strong solid acid catalyst for the synthesis of bio-based tributyl citrate from the esterification of citric acid and n-butanol.γ-Aminopropyltriethoxysilane(APTES)was first grafted on the TS-1 zeolite via the condensation reactions with surface hydroxyl groups,and subsequently the HPW was immobilized via the reaction between the amino groups and the protons from HPW-forming strong ionic bonding.The Keggin structure of HPW and MFI topology of TS-1 zeolite were well maintained after the modifications.The amino-functionalization generated abundant uniformly distributed active sites on TS-1 for HPW immobilization,which promoted the dispersity,abundance,as well as the stability of the acid sites.The tetrahedrally coordinated framework titanium and non-framework titania behaved as weak Lewis acid sites,and the protons from the immobilized HPW acted as the moderate or strong Brønsted acid sites.An optimized TBC yield of 96.2%(mol)with a conversion of-COOH of 98.1%(mol)was achieved at 150℃for 6 h over the HPW immobilized on amino-functionalized TS-1.The catalyst exhibited good stability after four consecutive reaction runs,where the activity leveled off at still a relatively high level after somewhat deactivation possibly caused by the leaching of a small portion of weakly anchored APTES or HPW. 展开更多
关键词 AMINO-FUNCTIONALIZATION Phosphotungstic acid TS-1 zeolite ESTERIFICATION Tributyl citrate
下载PDF
Usefulness of Newly Devised Clomiphene Citrate Administration Method Compared with the Conventional Method in Ovulation and Pregnancy
2
作者 Makoto Kawamura Misaki Akiyama +3 位作者 Remi Nakajima Eri Satoi Yoko Ogaki Rieko Kanda 《Open Journal of Obstetrics and Gynecology》 2024年第4期637-649,共13页
Objective: Since not all women wish to conceive a child through aggressive treatment, we investigated the usefulness of modified repeated intracyclic clomiphene citrate (CC) therapy (repeated CC therapy) as a newly de... Objective: Since not all women wish to conceive a child through aggressive treatment, we investigated the usefulness of modified repeated intracyclic clomiphene citrate (CC) therapy (repeated CC therapy) as a newly devised administration method. Methods: We evaluated the effects of CC administration on menstrual cycle length and retrospectively compared ovulation and pregnancy in 220 women who received CC at our hospital. Patients in the conventional method group received 50 mg per day for five days, starting on the fifth day of menstruation (withdrawal bleeding). Groups with and without menstrual cycle shortening after conventional CC administration were compared. The repeated CC therapy group was also compared with the non-shortened group. Repeated CC therapy was administered for the first five days as in the conventional method, and a second five-day repeat treatment was administered after an interval of five to seven days. Pregnancy rates, including indirect pregnancies, were evaluated by three different methods. Results: Ovulation and pregnancy rates were significantly better in the shortened group than in the non-shortened group (P < 0.001 and P = 0.010, respectively). Even in the non-shortened group, ovulation and pregnancy rates including indirect pregnancies were significantly improved when ovulation was observed with repeated CC therapy (P < 0.001 and P = 0.022, respectively). Conclusions: For patients whose menstrual cycle was not improved or shortened, repeated CC therapy as the newly devised CC administration method is useful as the next step after the conventional CC administration method. 展开更多
关键词 Clomiphene citrate INFERTILITY Menstrual Cycle Ovulation Induction
下载PDF
Analysis of the Effect of High-Dose Segmental Citrate Anticoagulation in High Flux Hemodialysis
3
作者 Xubo Fu 《Journal of Clinical and Nursing Research》 2024年第5期95-99,共5页
Objective:To analyze the clinical effect of high-dose citrate in segmental extracorporeal anticoagulation for high-throughput hemodialysis.Methods:The subjects included in this study were admitted to the hospital for ... Objective:To analyze the clinical effect of high-dose citrate in segmental extracorporeal anticoagulation for high-throughput hemodialysis.Methods:The subjects included in this study were admitted to the hospital for maintenance hemodialysis treatment from January 2021 to January 2023.All patients had a high risk of bleeding and received 4%trisodium citrate anticoagulant treatment,administered at a rate of 200 mL/h before and after the dialyzer.The anticoagulant effects achieved by the patients were observed and analyzed.Results:The total number of patients who received high-dose segmented citrate extracorporeal anticoagulation dialysis treatment was 50,with each patient undergoing 100 treatments.During the treatment,2 patients had to end the treatment early due to transmembrane pressure exceeding 30 mmHg and an increase in venous pressure exceeding 250 mmHg;the treatment times for these patients were 20 minutes and 200 minutes,respectively.The remaining patients successfully completed the 4-hour treatment.Blood pH and calcium ion concentration in the venous pot were monitored.It was observed that before dialysis,after 2 hours of dialysis,and at the end of dialysis,the blood pH of the patients remained within a relatively normal range.Although some patient levels changed after dialysis,they remained within the normal range.No adverse reactions(such as numbness of the limbs or convulsions)were observed during the anticoagulant treatment.Conclusion:Administering 4%trisodium citrate at a rate of 200 mL/h before and after the dialyzer achieves a good anticoagulant effect,maintains the patient’s blood gas levels within the normal range at the end of dialysis,and causes no adverse reactions. 展开更多
关键词 High dose Segmented citrate High flux HEMODIALYSIS Anticoagulation effect
下载PDF
Preparation of high active Pt/C cathode electrocatalyst for direct methanol fuel cell by citrate-stabilized method 被引量:3
4
作者 蒋庆来 彭忠东 +3 位作者 谢晓峰 杜柯 胡国荣 刘业翔 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2011年第1期127-132,共6页
Platinum nanoparticles supported on carbons(Pt/C,60%,mass fraction) electrocatalysts for direct methanol fuel cell(DMFC) were prepared by citrate-stabilized method with different reductants and carbon supports.The... Platinum nanoparticles supported on carbons(Pt/C,60%,mass fraction) electrocatalysts for direct methanol fuel cell(DMFC) were prepared by citrate-stabilized method with different reductants and carbon supports.The catalysts were characterized by X-ray diffraction(XRD),transmission electron microscopy(TEM) and cyclic voltammetry(CV).It is found that the size of Pt nanoparticles on carbon is controllable by citrate addition and reductant optimization,and the form of carbon support has a great influence on electrocatalytic activity of catalysts.The citrate-stabilized Pt nanoparticles supported on BP2000 carbon,which was reduced by formaldehyde,exhibit the best performance with about 2 nm in diameter and 66.46 m2/g(Pt) in electrocatalytic active surface(EAS) area.Test on single DMFC with 60%(mass fraction) Pt/BP2000 as cathode electrocatalyst showed maximum power density at 78.8 mW/cm2. 展开更多
关键词 direct methanol fuel cell CATALYST PT/C citrate reductant carbon support
下载PDF
Electrochemical reduction process of Co(Ⅱ) in citrate solution 被引量:5
5
作者 刘燕 李喆珺 +1 位作者 王益成 王为 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2014年第3期876-883,共8页
Effects of citrate concentration and pH on the electrochemical reduction process of Co(Ⅱ) were investigated by cyclic voltammetry(CV) and electrochemical impedance spectroscopy(EIS). The results show that Co(... Effects of citrate concentration and pH on the electrochemical reduction process of Co(Ⅱ) were investigated by cyclic voltammetry(CV) and electrochemical impedance spectroscopy(EIS). The results show that Co(Ⅱ) is reduced into two species which are free Co2+ and [Co(C6H607)] in the solution composed of 0.05 mol/L CoS04·5H2O, 0.20 mol/L Na2SO4 and 0-0.40 mol/L C6H5O7Na3·2H2O in the pH range of 3-9. The reduction behavior depends on the pH of the solution. Co(H) is mainly reduced into the form of free Co^2+ at pH 3 and into the form of [Co(C6H6O7)] at the pH range of 4-6 in citrate solution. The [Co(C6H6O7)] is first reduced to an intermediate state and then to Co°. Adsorption of the intermediate state exists on the surface of the electrode. Co(Ⅱ) is difficult to be reduced in the solution with the pH above 7, because the existing Co(Ⅱ)-citrate complex species [Co(C6H5O7)]- and [Co(C6H4O7)]2- are more difficult to be reduced than the hydrogen ion. 展开更多
关键词 Co(Ⅱ) ion electrochemical reduction process citrate complex species
下载PDF
几种常用的核染色标记物pH 6.0 Citrate和pH 9.0 Tris/EDTA修复液的比较
6
作者 张燕萍 郭志琴 +3 位作者 唐正英 王振 张怡 邬万新 《浙江创伤外科》 2013年第3期315-317,共3页
目的探讨pH 6.0 Citrate和pH 9.0 Tris/EDTA两种修复液在常用的免疫组化核染色标记物中的染色效果。方法选取本科室常用的3种核/浆标记抗体以及22种核标记抗体分别采用pH 6.0 Citrate和pH 9.0 Tris/EDTA微波热修复进行比较。结果在25种... 目的探讨pH 6.0 Citrate和pH 9.0 Tris/EDTA两种修复液在常用的免疫组化核染色标记物中的染色效果。方法选取本科室常用的3种核/浆标记抗体以及22种核标记抗体分别采用pH 6.0 Citrate和pH 9.0 Tris/EDTA微波热修复进行比较。结果在25种抗体中,其中有11种分别用pH 6.0 Citrate和pH 9.0 Tris/EDTA微波修复染色效果基本一致,在其余14种抗体中,有11种用pH 9.0 Tris/EDTA微波热修复方法进行修复时,阳性信号明显增强;而有3种抗体用pH 6.0 Citrate微波热修复方法进行修复时,阳性信号稍增强。结论对于这25种抗体来说,如果用微波加热的方法进行抗原修复,那么pH 9.0 Tris/EDTA优于PH 6.0 Citrate。 展开更多
关键词 抗原修复技术 PH 6 0 citrate PH 9 0 TRIS EDTA 核染色标记物
下载PDF
治疗伴有中至严重血小板减少的骨髓纤维化新药——枸橼酸帕西替尼(pacritinib citrate)
7
作者 陈本川 《医药导报》 CAS 北大核心 2022年第11期1717-1722,共6页
骨髓纤维化是一种罕见的骨髓进行性恶性肿瘤,破坏健康血细胞的正常产生,导致骨髓衰竭和严重贫血。帕西替尼(pacritinib)的激酶谱显示其对急性髓系白血病、骨髓增生异常综合征、慢性单核粒细胞白血病和慢性淋巴细胞白血病具有潜在的治疗... 骨髓纤维化是一种罕见的骨髓进行性恶性肿瘤,破坏健康血细胞的正常产生,导致骨髓衰竭和严重贫血。帕西替尼(pacritinib)的激酶谱显示其对急性髓系白血病、骨髓增生异常综合征、慢性单核粒细胞白血病和慢性淋巴细胞白血病具有潜在的治疗作用。枸橼酸帕西替尼最初由美国细胞疗法公司开发,2009年1月与美国S*BIO和Onyx制药公司签订开发和商业化协议,成立美国CTI生物制药公司,重点开发枸橼酸帕西替尼,用于治疗骨髓增生和移植物抗宿主病等疾病。2012年4月,成立CTI生物制药公司,与美国S*BIO和Onyx制药公司重新签订协议,CTI将收回帕西替尼全球开发权利。2020年10月13日CTI生物制药公司向美国食品药品管理局(FDA)提交滚动新药申请,寻求批准枸橼酸帕西替尼用于治疗严重血小板减少症(血小板计数<50×10^(9)·L^(-1))的骨髓纤维化。2022年2月28日,美国FDA批准枸橼酸帕西替尼胶囊上市,商品名Vonjo®,用于治疗成人血小板计数<50×10^(9)·L^(-1)的中高危原发性或继发性(真性红细胞增多症后或原发性血小板增多症)的骨髓纤维化。该文对枸橼酸帕西替尼胶囊的非临床和临床药理毒理学、临床研究、不良反应、适应证、剂量与用法、用药注意事项及知识产权状态和国内外研究进展等进行介绍。 展开更多
关键词 枸橼酸帕西替尼 骨髓纤维化 血小板减少 pacritinib citrate
下载PDF
Efficacy of mosapride citrate with polyethylene glycol solution for colonoscopy preparation 被引量:23
8
作者 Masahiro Tajika Yasumasa Niwa +12 位作者 Vikram Bhatia Hiroki Kawai Shinya Kondo Akira Sawaki Nobumasa Mizuno Kazuo Hara Susumu Hijioka Kazuya Matsumoto Yuji Kobayashi Akira Saeki Asana Akabane Koji Komori Kenji Yamao 《World Journal of Gastroenterology》 SCIE CAS CSCD 2012年第20期2517-2525,共9页
AIM:To evaluate the efficacy and safety of adjunctive mosapride citrate for bowel preparation before colonoscopy. METHODS:We conducted a randomized,double-blind, placebo-controlled study with mosapride in addition to ... AIM:To evaluate the efficacy and safety of adjunctive mosapride citrate for bowel preparation before colonoscopy. METHODS:We conducted a randomized,double-blind, placebo-controlled study with mosapride in addition to polyethylene glycol(PEG)-electrolyte solution.Of 250 patients undergoing colonoscopy,124 were randomized to receive 2 L PEG plus 15 mg of mosapride citrate (mosapride group),and 126 received 2 L PEG plus placebo(placebo group).Patients completed a questionnaire reporting the acceptability and tolerability of the bowel preparation process.The efficacy of bowel preparation was assessed by colonoscopists using a 5-point scale based on Aronchick's criteria.The primary end point was optimal bowel preparation rates(scores of excellent/good/fair vs poor/inadequate). RESULTS:A total of 249 patients were included in the analysis.In the mosapride group,optimal bowel preparation rates were significantly higher in the left colon compared with the placebo group(78.2%vs 65.6%,P<0.05),but not in the right colon(76.5%vs 66.4%,P=0.08).After excluding patients with severe constipation,there was a significant difference in bowel preparation in both the left and right colon(82.4%vs 66.7%,80.8%vs 67.5%,P<0.05,P<0.01).The incidence of adverse events was similar in both groups. Among the subgroup who had previous colonoscopy experience,a significantly higher number of patients in the mosapride group felt that the current preparation was easier compared with patients in the placebo group(34/72 patients vs 24/74 patients,P<0.05). CONCLUSION:Mosapride citrate may be an effective and safe adjunct to PEG-electrolyte solution that leads to improved quality of bowel preparation,especially in patients without severe constipation. 展开更多
关键词 Mosapride citrate Bowel preparation Polyethylene glycol-electrolyte solution COLONOSCOPY PROKINETICS
下载PDF
Absorption of Sulphur Dioxide with Sodium Citrate Buffer Solution in a Rotating Packed Bed 被引量:24
9
作者 JIANG Xiuping LIU Youzhi GU Meiduo 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2011年第4期687-692,共6页
Absorption of SO2 from a SO2/air mixture with sodium citrate buffer solution was investigated using a rotating packed bed(RPB) in laboratory scale.The effects of operating parameters,such as the rotation speed of RPB,... Absorption of SO2 from a SO2/air mixture with sodium citrate buffer solution was investigated using a rotating packed bed(RPB) in laboratory scale.The effects of operating parameters,such as the rotation speed of RPB,liquid-gas ratio,inlet gas flow rate,inlet concentration of SO2 in flue gas,sodium citrate buffer concentration and initial pH of absorption solution,on the SO2 concentration in the absorption solution or removal efficiency of SO2 were examined.Incremental rate of sulfate radical ions in the absorption solution was also examined.Experimental results indicate that the efficiency of this regenerative process will be improved by using RPB under appropriate operating conditions,and the generation of SO2-4 will be restrained in the process in RPB. 展开更多
关键词 SO2 absorption rotating packed bed sodium citrate buffer solution
下载PDF
Removal of citrate and hypophosphite binary components using Fenton,photo-Fenton and electro-Fenton processes 被引量:9
10
作者 Yao-Hui Huang Hsiao-Ting Su Li-Way Lin 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2009年第1期35-40,共6页
Both citrate and hypophosphite in aqueous solution were degraded by advanced oxidation processes (Fe^2+/H2O2, UV/Fe^2+/H2O2, and electrolysis/Fe^2+/H2O2) in this study. Comparison of these techniques in oxidation... Both citrate and hypophosphite in aqueous solution were degraded by advanced oxidation processes (Fe^2+/H2O2, UV/Fe^2+/H2O2, and electrolysis/Fe^2+/H2O2) in this study. Comparison of these techniques in oxidation efficiency was undertaken. It was found that Fenton process could not completely degrade citrate in the presence of hypophosphite since it caused a series inhibition. Therefore, UV light (photo-Fenton) or electron current (electro-Fenton) was applied to improve the degradation efficiency of the Fenton process. Results showed that both photo-Fenton and electro-Fenton processes could overcome the inhibition of hypophosphite, especially the electro-Fenton. 展开更多
关键词 citrate HYPOPHOSPHITE WASTEWATER advanced oxidation processes FENTON PHOTO-FENTON ELECTRO-FENTON
下载PDF
Catalysis of Manganese(II) on Chromium(VI) Reduction by Citrate 被引量:12
11
作者 LIChen LAN Ye-Qing DENG Bao-Lin 《Pedosphere》 SCIE CAS CSCD 2007年第3期318-323,共6页
The catalysis of manganese(Ⅱ) (Mn^2+) on chromium(Ⅵ) (Cr^6+) reduction by citrate was studied through batch experiments with the concentration of citrate greatly in excess of Cr^6+ at 25 ℃ and in pH rang... The catalysis of manganese(Ⅱ) (Mn^2+) on chromium(Ⅵ) (Cr^6+) reduction by citrate was studied through batch experiments with the concentration of citrate greatly in excess of Cr^6+ at 25 ℃ and in pH ranges of 4.0 go 5.0. Results showed that at pH 4.5 within 22 h direct reduction of Cr^6+ by citrate was not observed, bug for the same time when Mn^2+ (50 to 200 μmol L^-1) was added, nearly all Cr^6+ was reduced, with the higher initial Mn^2+ concentration having faster Cr^6+ reduction. In the initial stage of the reaction, the Cr^6+ reduction could be described with a pseudo-first-order kinetics equation. In the lager stage of the reaction, plots of lnc(Cr^6+) versus t, where c(Cr^6+) is the Cr^6+ concentration in the reaction and t is the reaction time, deviated from the initial linear trend. The deviations suggested that the pseudo-first-order kinetics did not apply go the whole experimental period and that some reaction intermediates could have greatly accelerated Cr^6+ reduction by citrate. The catalysis of the intermediates increased with the reaction time and gradually reached stability. Then, the plot of lnc(Cr^6+) versus t in the presence of Mn^2+ was linear again, with the rate constant increasing by 102 times compared with the absence of Mn^2+. Complexation between Mn^2+ and citrate was likely a prerequisite for the catalysis of Mn^2+ on the reaction. Additional experiments showed that introducing eghylenediaminegegraacegic acid (EDTA) into the reaction system strongly suppressed the catalysis of Mn^2+. 展开更多
关键词 CATALYSIS chromium(Ⅵ) citrate manganese(Ⅱ) REDUCTION
下载PDF
Can mosapride citrate reduce the volume of lavage solution for colonoscopy preparation? 被引量:8
12
作者 Masahiro Tajika Yasumasa Niwa +8 位作者 Vikram Bhatia Shinya Kondo Tsutomu Tanaka Nobumasa Mizuno Kazuo Hara Susumu Hijioka Hiroshi Imaoka Koji Komori Kenji Yamao 《World Journal of Gastroenterology》 SCIE CAS 2013年第5期727-735,共9页
AIM:To evaluate the possibility of reducing the volume of polyethylene glycol(PEG)-electrolyte solution using adjunctive mosapride citrate for colonoscopy preparation. METHODS:This was a single-center,prospective, ran... AIM:To evaluate the possibility of reducing the volume of polyethylene glycol(PEG)-electrolyte solution using adjunctive mosapride citrate for colonoscopy preparation. METHODS:This was a single-center,prospective, randomized,investigator-blinded,non-inferiority study involving 252 patients of both sexes,aged from 20 to 80 years,scheduled for screening or diagnostic colonoscopy in our department.A total of 126 patients was randomized to receive 1.5 L PEG-electrolyte solution plus 15 mg of mosapride(1.5 L group),and 126 received 2 L PEG-electrolyte solution plus 15 mg of mosapride(2 L group).Patients completed a questionnaire on the acceptability and tolerability of the bowel preparation process.The efficacy of bowel preparation was assessed using a 5-point scale based on the Aronchick scale.The primary end point was adequate bowel preparation rates(score of excellent/good/fair) vs(poor/inadequate).Acceptability and tolerability,as well as disease detection,were secondary end points. RESULTS:A total of 244 patients was included in the analysis.There were no significant differences between the 2 L and 1.5 L groups in age,sex,body mass index, number of previous colonoscopies,and the preparation method used previously.The adequate bowel preparation rates were 88.5%in the 2 L group and 82.8%in the 1.5 L group[95%lower confidence limit(LCL)for the difference=-14.5%,non-inferiority P=0.019]in the right colon.In the left colon,the adequate bowel preparation rates were 89.3%in the 2 L group and 81.1%in the 1.5 L group(95%LCL=-17.0%,non-inferiority P=0.066).Compliance,defined as complete (100%)intake of the PEG solution,was significantly higher in the 1.5 L group than in the 2 L group(96.8% vs 85.7%,P=0.002).The proportion of abdominal distension(none/mild/moderate/severe)was significantly lower in the 1.5 L group than in the 2 L group (36/65/22/3 vs 58/48/18/2,P=0.040).Within the subgroup who had undergone colonoscopy previously, a significantly higher number of patients in the 1.5 L group than in the 2 L group felt that the current preparation was easier than the previous one(54.1%vs 28.0%,P=0.001).The disease detection rate was not significantly different between the two groups. CONCLUSION:Although the 1.5 L group had better acceptability and tolerability,15 mg of mosapride may be insufficient to compensate for a 0.5-L reduction of PEG solution. 展开更多
关键词 MOSAPRIDE citrate Bowel PREPARATION Polyethylene glycol-electrolyte SOLUTION PROKINETICS COLONOSCOPY
下载PDF
Management of regional citrate anticoagulation for continuous renal replacement therapy:guideline recommendations from Chinese emergency medical doctor consensus 被引量:9
13
作者 Shu-Yuan Liu Sheng-Yong Xu +11 位作者 Lu Yin Ting Yang Kui Jin Qiu-Bin Zhang Feng Sun Ding-Yu Tan Tian-Yu Xin Yu-Guo Chen Xiao-Dong Zhao Xue-Zhong Yu Jun Xu Emergency Medical Doctor Branch of the Chinese Medical Doctor Association 《Military Medical Research》 SCIE CAS CSCD 2023年第6期733-750,共18页
Continuous renal replacement therapy(CRRT)is widely used for treating critically-ill patients in the emergency department in China.Anticoagulant therapy is needed to prevent clotting in the extracorporeal circulation ... Continuous renal replacement therapy(CRRT)is widely used for treating critically-ill patients in the emergency department in China.Anticoagulant therapy is needed to prevent clotting in the extracorporeal circulation during CRRT.Regional citrate anticoagulation(RCA)has been shown to potentially be safer and more effective,and is now recommended as the preferred anticoagulant method for CRRT.However,there is still a lack of unified standards for RCA management in the world,and there are many problems in using this method in clinical practice.The Emergency Medical Doctor Branch of the Chinese Medical Doctor Association(CMDA)organized a panel of domestic emergency medicine experts and international experts of CRRT to discuss RCA-related issues,including the advantages and disadvantages of RCA in CRRT anticoagulation,the principle of RCA,parameter settings for RCA,monitoring of RCA(mainly metabolic acid-base disorders),and special issues during RCA.Based on the latest available research evidence as well as the paneled experts'clinical experience,considering the generalizability,suitability,and potential resource utilization,while also balancing clinical advantages and disadvantages,a total of 16 guideline recommendations were formed from the experts'consensus. 展开更多
关键词 Continuous renal replacement therapy EMERGENCY ANTICOAGULATION citrate GUIDELINE Expert consensus
下载PDF
Magnesium citrate with a single dose of sodium phosphate for colonoscopy bowel preparation 被引量:7
14
作者 Yong Sung Choi Jung Pil Suh +5 位作者 Jong Kyu Kim In Taek Lee Eui Gon Youk Doo Seok Lee Do Sun Kim Doo Han Lee 《World Journal of Gastroenterology》 SCIE CAS CSCD 2011年第2期242-248,共7页
AIM:To evaluate the efficacy and acceptability of magnesium citrate and a single dose of oral sodium phosphate(45 mL) solution for morning colonoscopy bowel preparation. METHODS:A total of 159 patients were randomly a... AIM:To evaluate the efficacy and acceptability of magnesium citrate and a single dose of oral sodium phosphate(45 mL) solution for morning colonoscopy bowel preparation. METHODS:A total of 159 patients were randomly assigned to receive two split doses of 90 mg of sodium phosphate(GroupⅠ,n=79) or magnesium citrate(250 mL,the day before the procedure) followed by 45 mL of sodium phosphate(the day of procedure,GroupⅡ,n= 80) .The quality of bowel cleansing and the acceptability of each regimen were compared,including the satisfaction,taste,willing to repeat and adverse effects of each regimen. RESULTS:The quality of bowel cleansing of GroupⅡ was as good as that of GroupⅠ(An Aronchick scale score of good or excellent:70.9%vs 81.0%,respectively,P=0.34;the Ottawa system score:4.4±2.6 vs 3.8 ±3.0,respectively,P=0.76) .There was no statisticallysignificant difference between both groups with regard to acceptability,including the satisfaction,taste and willingness to repeat the regimen.A significantly greater number of older patients(over 65 years old) in Group Ⅱgraded the overall satisfaction as satisfactory(48.1% vs 78.1%,respectively;GroupⅠvs GroupⅡ,P=0.01) . There were no significant adverse reactions. CONCLUSION:Magnesium citrate and a single dose of sodium phosphate was as effective and tolerable as the conventional sodium phosphate regimen and is a satisfactory option. 展开更多
关键词 COLONOSCOPY Bowel preparation EFFICACY ACCEPTABILITY Magnesium citrate Sodium phosphate
下载PDF
Study on Desorbing Sulfur Dioxide from Citrate Solution by Ultrasonlficatlon 被引量:7
15
作者 薛娟琴 孟令嫒 +2 位作者 沈彬彬 杜士毅 兰新哲 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2007年第4期486-491,共6页
Using a sonochemical reactor designed by the authors,the process of removing sulfur dioxide from cit- rate solution simulating the flue gas desulfurization was studied.The influence of ultrasonic frequency,ultrasonic ... Using a sonochemical reactor designed by the authors,the process of removing sulfur dioxide from cit- rate solution simulating the flue gas desulfurization was studied.The influence of ultrasonic frequency,ultrasonic power,reaction temperature,stirring speed,inert gases,initial concentration of sulfur dioxide and concentration of citrate on the efficiency of sulfur dioxide desorption,the stability of citrate solution and the concentration of sulfate radical was examined systematically.By comparing the desorption of sulfur dioxide with and without ultrasonifica- tion,it was concluded that(1)lower ultrasonic frequency results in a better degassing efficiency;(2)the use of ul- trasonification in desorbing sulfur dioxide from citrate solution improves the desorbing efficiency in some condi- tions,without changing the essence of chemical reactions;(3)sparging inert gas into the liquid can lower the vis- cosity of solution and the cavitating threshold,and raise the desorption efficiency.These results demonstrate a technical way for deep desorption of sulfur dioxide and provide the fundamental data for future industrial disposal of sulfur dioxide. 展开更多
关键词 flue gas desulphurization desorption efficiency ultrasonic degassing citrate acoustic cavitation
下载PDF
Competitive and cooperative adsorption of arsenate and citrate on goethite 被引量:5
16
作者 SHI Rong,JIA Yongfeng,WANG Chengzhi Institute of Applied Ecology,Chinese Academy of Sciences,Shenyang 110016,China 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2009年第1期106-112,共7页
The fate of arsenic in natural environments is influenced by adsorption onto metal (hydr)oxides. The extent of arsenic adsorption is strongly affected by coexisting dissolved natural organic acids. Recently, some st... The fate of arsenic in natural environments is influenced by adsorption onto metal (hydr)oxides. The extent of arsenic adsorption is strongly affected by coexisting dissolved natural organic acids. Recently, some studies reported that there existed competitive adsorption between arsenate and citrate on goethite. Humic acid is known to interact strongly with arsenate by forming complexes in aqueous solution, hence it is necessary to undertake a comprehensive study of the adsorption of arsenate/citrate onto goethite in the presence of one another. The results showed that at the arsenate concentrations used in this study (0.006-0.27 mmol/L), citrate decreased arsenate adsorption at acidic pH but no effect was observed at alkaline pH. In comparison, citrate adsorption was inhibited at acidic pH, but enhanced at alkaline pH by arsenate. This was probably due to the formation of complex between arsenate and citrate like the case of arsenate with humic acid. These results implied that the mechanism of the adsorption of arsenate and citrate onto goethite in the presence of one another involved not only competition for binding sites, but the cooperation between the two species at the watergoethite interface as well. 展开更多
关键词 ADSORPTION ARSENATE citrate GOETHITE
下载PDF
Assessment of heme oxygenase-1 (HO-1) activity in the cavernous tissues of sildenafil citrate-treated rats 被引量:4
17
作者 M. Talaat Abdel Aziz M. Farid Al-Asmar +5 位作者 Taymour Mostafa Hazem Atta Laila Rashed Dina Sabry Shedeed Ashour Ahmed T. Abdel Aziz 《Asian Journal of Andrology》 SCIE CAS CSCD 2007年第3期377-381,共5页
Aim: To assess heine oxygenase-1 (HO-1) activity in the cavemous tissue of sildenafil citrate-treated rats. Methods: One hundred and ninety-two Sprague-Dawley male rats, divided into four equal groups, were invest... Aim: To assess heine oxygenase-1 (HO-1) activity in the cavemous tissue of sildenafil citrate-treated rats. Methods: One hundred and ninety-two Sprague-Dawley male rats, divided into four equal groups, were investigated. Group 1, the control group, received regular animal chow; group 2 received sildenafil citrate by intragastric tube; group 3 received sildenafil and HO inhibitor (zinc protoporphyrin, ZnPP); and group 4 received sildenafil and nitric oxide synthase (NOS) inhibitor L-nitroarginine methyl ester (L-NAME). Twelve rats from each group were killed after 0.5 h, 1 h, 2 h and 3 h of drug administration. Then HO-1 activity, cGMP levels and NOS enzymatic activity in the cavernous tissues were estimated. Results: In cavemous tissue, HO-1 activity, NOS enzymatic activity and cGMP concentration increased significantly in sildenafil-treated rats compared to other groups throughout the experiment. Rats receiving either HO or NOS inhibitors showed a significant decrease in these parameters. HO- 1 cavemous tissue activity and NOS enzymatic activity demonstrated a positive significant correlation with cGMP levels (r = 0.646, r = 0.612 respectively; P 〈 0.001). Conclusion: The actions of PDE5 inhibitor sildenafil citrate in the cavernous tissue are partly mediated through the interdependent relationship between both HO-1 and NOS activities. 展开更多
关键词 erectile dysfunction heme oxygenase sildenafil citrate nitric oxide synthase carbon monoxide
下载PDF
Effect of calcium citrate on bone integration in a rabbit femur defect model 被引量:3
18
作者 Wei Zhang Wei Wang +13 位作者 Qing-Yu Chen Zhong-Qin Lin Shao-Wen Cheng Dong-Quan Kou Xiao-Zhou Ying Yue Shen Xiao-Jie Cheng Peng-Fei Nie Xiu-Cui Li Ferdinand An Rompis Hang Huang Hua Zhang Zhong-Lin Mu Lei Peng 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2012年第4期310-314,共5页
Objective:To explore effect of calcium citrate on bone integration in a rabbit femur defect model, and to compare the bone formation with different sizes by radiological and histological study. Methods:Twenty-four mal... Objective:To explore effect of calcium citrate on bone integration in a rabbit femur defect model, and to compare the bone formation with different sizes by radiological and histological study. Methods:Twenty-four male Japanese white rabbits were randomly divided into three groups (Group A.B.C)in this study.Under anesthesia,defects of four sizes(1.2,1.5,2.0 and 2.5 mm) were created in each of the rabbits.Commercially pure calcium citrate powder was placed inside the medullary compartment of the femur(Experimental),while in the contralateral femur(Control) nothing was implanted.The defects were analyzed using radiography and histological analysis by using Imagepro-Plus 6.0 software after animal was sacrificed at 4th(Group A),6th(Group B) and 8th(Group C) weeks postoperatively.Four samples were analyzed for each size of defect and each healing period.Results:The histological and the radiologic evaluation were performed after sacrification of all rabbits on postoperative 4th and 6th weeks,It showed significant difference between the experimental group and the control group when these defects were less than or equal to 2.0 mm.No statistical difference was observed when these defects were larger than 2.0 mm at all healing periods except at the 4th week.Conclusions:Calcium citrate affects the early periods of hone defects healing mechanism in Japanese white rabbits positively,especially when the defect is not too large,We suggest further studies on calcium citrate to determine the effects of various dosages,administration ways and the experimental time on the bone defects. 展开更多
关键词 Experiment BONE Fracture HEALING CALCIUM citrate
下载PDF
Addition of senna improves quality of colonoscopy preparation with magnesium citrate 被引量:3
19
作者 Stergios Vradelis Evangelos Kalaitzakis +4 位作者 Yalda Sharifi Otto Buchel Satish Keshav Roger W Chapman Barbara Braden 《World Journal of Gastroenterology》 SCIE CAS CSCD 2009年第14期1759-1763,共5页
AIM: To prospectively investigate the effectiveness and patient’s tolerance of two low-cost bowel cleansing preparation protocols based on magnesium citrate only or the combination of magnesium citrate and senna. MET... AIM: To prospectively investigate the effectiveness and patient’s tolerance of two low-cost bowel cleansing preparation protocols based on magnesium citrate only or the combination of magnesium citrate and senna. METHODS: A total of 342 patients who were referred for colonoscopy underwent a colon cleansing protocol with magnesium citrate alone (n = 160) or magnesium citrate and senna granules (n = 182). The colonoscopist rated the overall efficacy of colon cleansing using an established score on a 4-point scale. Patients were questioned before undergoing colonoscopy for side effects and symptoms during bowel preparation. RESULTS: The percentage of procedures rescheduled because ofinsufficient colon cleansing was 7% in the magnesium citrate group and 4% in the magnesium citrate/senna group (P = 0.44). Adequate visualization of the colonic mucosa was rated superior under the citramag/senna regimen (P = 0.004). Both regimens were well tolerated, and did not significantly differ in the occurrence of nausea, bloating or headache.However, abdominal cramps were observed more often under the senna protocol (29.2%) compared to the magnesium citrate only protocol (9.9%, P < 0.0003). CONCLUSION: The addition of senna to the bowel preparation protocol with magnesium citrate significantly improves the cleansing outcome. 展开更多
关键词 COLONOSCOPY Bowel preparation SENNA Magnesium citrate POLYP
下载PDF
Treatment preferences in men with erectile dysfunction: an open label study in Korean men switching from sildenafil citrate to tadalafil 被引量:3
20
作者 Tai Young Ahn Sung Won Lee +8 位作者 Sae-Woong Kim Dae Yul Yang Nam Cheol Park Kweon-Sik Min Kwangsung Park Jae-Seung Paick Yulia Dyachkova Trisha Dwight Myung-Sea Luke Lee 《Asian Journal of Andrology》 SCIE CAS CSCD 2007年第6期760-770,共11页
To evaluate patient preferences for sildenafil citrate or tadalafil (PDE-5 inhibitors available for the treatment of erectile dysfunction [ED]) and assess potential reasons for these preferences. Methods: This open... To evaluate patient preferences for sildenafil citrate or tadalafil (PDE-5 inhibitors available for the treatment of erectile dysfunction [ED]) and assess potential reasons for these preferences. Methods: This open-label study was conducted on Korean men taking sildenafil, at least 6 weeks prior to study entry, for ED. Following screening, patients continued sildenafil treatment for 4 weeks, then after a 1-week washout period, switched to tadalafil for 8 weeks. Patients then continued with their treatment of choice during an extension phase. Psychosocial factors (time concern, spontaneity, sexual self-confidence) were evaluated using Psychological and Interpersonal Relation- ship Scales (PAIRS), while timing of dose to sexual attempt patterns were assessed from patient diaries. Results: The present study enrolled 160 Korean men (mean age 55 years) with prior median sildenafil use of 585 days. During the extension phase, 73.7% of patients elected to take tadalafil, whereas 26.3% chose sildenafil (P 〈 0.001). After switching from sildenafil to tadalafil, mean PAIRS time concern scores decreased from 2.54 to 2.42 (P = 0.002), with no statistically significant differences observed between the sildenafil and tadalafil assessment phases in sexual spontaneity and self-confidence scores. Sexual attempts made 〉 4 h to 〈 36 h post-dose occurred in 4.5% of patients during the sildenafil assessment phase compared with 17.5% during the tadalafil assessment phase. Conclusion: After experiencing both sildenafil and tadalafil, the majority of patients exhibited a preference for tadalafil. This preference might be influenced by psychosocial factors, such as decreased time concerns, and a broader window of opportunity available for sexual activity. 展开更多
关键词 erectile dysfunction TADALAFIL sildenafil citrate Psychological and Interpersonal Relationship Scales PREFERENCE
下载PDF
上一页 1 2 12 下一页 到第
使用帮助 返回顶部