Maillard Products Formed from Chicken Fat Oxidants and Amino Acids Act as a Flavor Enhancer in Comminuted Chicken Products

Lipid oxidation and degradation are generally recognized as unfavorable reactions in food processing. However, lipids can be utilized to produce meat-like flavorings through reaction with amino acids after degradation to carbonyls such as aldehydes and ketones. The fatty acids in chicken fat mainly comprise palmitic acid, oleic acid and linoleic acid. After being heated at 120 ~C for 3 h, the degraded carbonyls of chicken fat were reacted with cysteine, alanine, glycine and thiamine to form a chicken-like flavoring. The key aromatic components of the flavoring were identified by GC-MS. In the overall volatile profile, 22 kinds of compound were detected, among which 2-furanmethanol was formed by the Maillard reaction, 1-（2-furanyl）-ethanone by cyclization and 2,4,6-trimethyl-l,3,5-trithiane by the Strecker degradation of cysteine. Dihydro-2-methyl-3（2H）-furanone, dihydro-2-methyl- 3（2H）-thiophenone, 2-acetyl-lH-pyrroline and 4-methyl-5-thiazoleethanol were the degradation products of thiamine. The prepared chicken flavoring was added to comminuted chicken product （CCP）. GC-MS analysis and sensory evaluation showed that the flavor and odor of the CCP were greatly enhanced.

The finite element analysis of cemented long and short stem prosthetic replacement in aged patients with comminuted intertrochanteric fracture

Objective To investigate the stress distribution of the femur after cemented prosthetic replacement in aged patients with comminuted intertrochanteric fracture and to analyze the difference of stress distribution between cemented long

Locking plate fixation combined with iliac crest bone autologous graft for proximal humerus comminuted fracture

Background Although the use of an intramedullary fibular allograft together with locking plate fixation can provide additional medial support and prevent varus malalignment in displaced proximal humeral fractures with promising results,the fibular autograft donor site often sustains significant trauma and cannot restore the articular surface of comminuted fractures.The aim of this study was to evaluate the clinical and radiographic outcomes of a locking plate and crest bone autologous graft for treating proximal humerus comminuted fractures.Methods We assessed the functional outcomes and complication rates in 40 patients with proximal humerus comminuted fractures.Eighteen patients were treated with a locking plate and an autologous crest bone graft （experimental group）,and 22 were treated with only the locking plate and no bone graft （control group）.Postoperative assessments included radiographic imaging,range of motion analysis,pain level based on the visual analogue scale （VAS）,and the SF-36 （Short Form （36） Health Survey）,as well as whether patients could retum to their previous occupation.Results All fractures healed both clinically and radiologically in the experimental group.There was no more than 2 mm collapse of the humeral head,and no osteonecrosis or screw penetration of the articular surface.In contrast,two patients had a nonunion in the control group,and they eventually accepted total shoulder replacements.The average time from surgery to radiographic union was significantly shorter in the experimental group （（4.66±1.63） months） compared with the control group （（5.98±1.57） months） （P ＜0.05）.For the experimental versus controls groups,the mean shoulder active flexion （148.00±18.59 vs.121.73±17.20） degrees,extension （49.00±2.22 vs.42.06±2.06） degrees,internal rotation （45.00±5.61 vs.35.00±3.55）degrees,external rotation （64.00±9.17 vs.52.14±5.73）degrees,and abduction （138.00±28.78 vs.105.95±15.66） degrees were all significantly higher （all P ＜0.001）.The median SF-36 in the experimental group （（88.00±5.71） points） was significantly higher than that of the control group （（69.45±9.45） points; P ＜0.001）.The median VAS pain level （mean rank,10.50） in the experimental group was lower than that （mean rank,47.19） of the control group （P ＜0.001）.All but one patient （17 of 18,94.4％） in the experimental group returned to their previous activities or occupations,and that one patient changed to a different occupation because of slight restrictions to activities.On the other hand,four patients could not return to their previous activities or occupations in the control group.Conclusion Locking plate fixation combined with an iliac crest bone graft is an effective technique for treating proximal humerus comminuted fractures.

Use of mineralized collagen bone graft substitutes and dorsal locking plate in treatment of elder metaphyseal comminuted distal radius fracture

Bone graft may be needed to fill bone defect in elderly patients with a metaphyseal comminuted distal radius fracture. In this retrospective, nonrandomized, single-surgeon study, we evaluated the clinical and radiologic outcomes of using both dorsal locking plates with or without augmentation with mineralized collagen （MC） bone graft for elderly patients with dorsally metaphyseal comminuted radius fractures. Patients in group 1 （n = 12） were treated with dorsal locking plates with MC bone graft application into the metaphyseal bone defect, and those in group 2 （n - 12） only with dorsal locking plates. Clinical and radiologic parameters were determined at three and 12 months after surgery. At final follow-up, no significant difference was noted between the 2 groups in terms of palmar tilt and radial inclination （p - 0.80）; however, ulnar variance increased significantly in the group 2 treated with dorsal locking plates without augmentation （p〈0.05）. Functionally, there was no significant difference between the groups. Our preliminary study suggests that combination of MC as bone-graft substitutes and dorsal locking plates may be a usefully alternative for elderly patients with metaphyseal comminuted distal radius fracture.

A comparative study of variable angle volar plate and bridging external fixator with K-wire augmentation in comminuted distal radius fractures

Purpose:Comminuted intraarticular distal radial fractures are difficult to treat conservatively and require operative treatment.This study compared the functional outcomes between variable angle volar plating and external fixator with K-wire augmentation in open reduction and internal fixation.Methods:A total of 62 adult patients with comminuted intraarticular distal radius fracture were randomized into 2 groups:volar plate group and external fixator group.These patients aged between 18 and 60 years had unilateral fractures,and agreed to be included in the study.Patients with a history of fracture,bilateral fracture,associated other injuries,delayed injury for more than 2 weeks,open fracture,pre-existing arthrosis or disability,psychiatric illness and pathological fracture were excluded.Patients were followed up at 6 weeks,3 months,6 months and 1 year.The assessment of pain,functional activity,range of motion and grip strength was done at each stage of follow-up.The pain and functional activities were assessed by patient rated wrist evaluation(PRWE)score and disabilities of the arm,shoulder and hand(DASH)score.Results:Patients in volar plate group had superior PRWE score and DASH score at each stage of followup.At 1 year follow-up,the mean PRWE score were 7.48 for volar plate group and 7.35 for external fixator group;while the mean DASH score was 4.65 for volar plate group and 5.61 for external fixator group.They had better flexion and extension range of movement.They also had better pronation and supination range of motion at initial follow-up,however the difference get attenuated by 1 year.Volar plate group had significantly better grip strength than external fixator group.Complication rates were higher in external fixation group.Conclusion:Fixation with variable angle volar plate results in early wrist mobilization,better range of movement,less pain and disability and early return of function.

Coupled exofixator for comminuted fracture of humeral shaft

Objective: To report and assess the efficacy of a coupled exofixator in the treatment of comminuted fracture of the humeral shaft.Methods: From June 1999 to September 2003, 24 patients with comminuted fracture of the humeral shaft were treated in our department, in whom 11 were involved in left humerus fractures and 13 in right humerus fractures. Closed reduction or open reduction with a small incision as well as a coupled exofixator was used to treat these patients. Results: All cases got anatomical reduction after 6-12 months follow-up. The time for fracture union averaged 5.8 months with a good functional recovery of the shoulder-elbow joints. Conclusions: The coupled exofixator is favorable to the treatment of comminuted humeral shaft fractures. It can shorten union time and avoid nonunion occurrence.

Use of tricortical iliac crest strut autograft in comminuted posterior wall acetabular fractures： A case series

Purpose： The results for fixation of comminuted posterior wall acetabular fractures are not very promising with reported complications in terms of osteoarthritis, nonunion and malunion which subsequently require conversion to total hip arthroplasty. The conversion to total hip arthroplasty is possible in patients over 50 years of age but not in younger patients. So this requires new methods for salvage of the native hip in young patients. Methods： There were six patients in our series with highly comminuted posterior wall acetabular frac- tures where the fragments were excised and the gap filled with tricortical anterior iliac-crest strut autograff, fixed with screws and plate. Results： Good results were achieved in four out of six patients analyzed clinically using the Merle d＇Aubinge score modified by Matta and radiologically by Matta scoring. These patients have returned to original work and are walking independently. The good result in one patient deteriorated from good to poor between one and two years. One patient developed infection and excision arthroplasty was done, The graft incorporated well in five out of six patients. Conclusion： The use of iliac crest autograff is a better, advanced and promising technique as it provides a new wall to the weight bearing dome of the acetabulum for articulation with the femoral head. The rates of nonunion, malunion, post traumatic osteoarthritis are less as compared to the fixation of the comminuted fragments. The need for conversion to total hio arthroolastv is also less.

Treatment of comminuted trochanteric fractures and non-union of trochanteric osteotomy in revision total hip arthroplasty

Objective: To explore the clinical efficacy of the treatment of comminuted trochanteric fractures and trochanteric osteotomy non union in revision total hip arthroplasty with tension band fixation. Methods: A retrospective review of 295 revision total hip operations performed between 1992 and 1998 was undertaken. Twenty hips of 19 patients with comminuted fractures or nonunion of the greater trochanter were stabilized with tension band technique. Multiple 2.0 mm k wires and tension band wires were placed through the intact cortex distally and the abductor tendon proximally in the pattern "8". Results: The average follow up was 30 months. The Harris Hip Score improved on average from 45 preoperatively to 89 at follow up. Sixteen hips with intra operative trochanteric fracture through osteolytic bone and four hips with symptomatic trochanteric nonunion were approached with tension band fixation. Perioperative loss of fixation in one patient required a repeated surgery. The same fixation at the second operation achieved an uneventful healing. Two patients had a 2 cm proximal migration of one K wire without loss of bony fixation. The trochanteric fractures healed with no further proximal wire migration. One patient had loss of fixation with trochanteric escape at 6 weeks post operatively. The patient has abductor weakness with Trendleburg limp but without pain. On average, radiographic examination showed that healing occurred at 16.6 weeks postoperatively. Six patients developed grade 1 heterotopic ossification and two patients grade 3. All were asymptomatic. None of the 19 patients experienced a dislocation during the follow up. Conclusions: Tension band fixation for greater trochanter can enhance the success rate of revision total hip arthroplasty without a deficient abductor mechanism.

Primary Clinical Research of a Patient Specific Implant System for an Old Zygomaticomaxillary Complex Comminuted Fracture

The objective of this study was to expound a novel surgical management technique assisted by patient-specific implants(PSIs)for comminuted fractures of the zygomaticomaxillary complex(ZMC).The aim of this study was to explore the feasibility of using PSIs to accurately restore and fix comminuted fractures.A male patient with an old ZMC comminuted fracture was used to describe the workflow,technique,and method.Computerassisted surgical simulation was used to determine the optimal plan for the reduction of bone segments prior to surgery.The PSIs were used to accurately guide the surgeon’s position of the bone segments,as planned,during the operation.Oral panoramic films and cephalometric films were taken immediately at 1,3,6,and 12 months after the operation,while computed tomography images of the whole skull were taken immediately,half a year,and one year after the operation.The patient’s follow-up showed that the zygomatic symmetry recovered well post-surgery and the patient was satisfied with the outcome.This new surgical method greatly improved the facial symmetry of this patient.

手术治疗开放性Pilon骨折

目的探讨开放性Pilon骨折手术方法及临床效果。方法根据软组织损伤程度及骨折的不同形态，采用不同手术方法进行治疗。结果获得随访12例，时间4～38个月。1例局部皮肤坏死，行VSD引流、植皮后愈合。2例术后出现张力性水泡，拆除外侧切口部分缝线，Ⅱ期缝合后愈合。优良9例，可2例，差1例，优良率91．7％。结论术前全面评估，正确的手术方法及精确的解剖复位，术后正确功能锻炼是提高开放性Pilon骨折疗效的关键。

Bench-to-bedside strategies for osteoporotic fracture: from osteoimmunology to mechanosensation

Osteoporosis is characterized by a decrease in bone mass and strength, rendering people prone to osteoporotic fractures caused by low-energy forces. The primary treatment strategy for osteoporotic fractures is surgery;however, the compromised and comminuted bones in osteoporotic fracture sites are not conducive to optimum reduction and rigid fixation. In addition, these patients always exhibit accompanying aging-related disorders, including high inflammatory status, decreased mechanical loading and abnormal skeletal metabolism, which are disadvantages for fracture healing around sites that have undergone orthopedic procedures. Since the incidence of osteoporosis is expected to increase worldwide, orthopedic surgeons should pay more attention to comprehensive strategies for improving the poor prognosis of osteoporotic fractures. Herein, we highlight the molecular basis of osteoimmunology and bone mechanosensation in different healing phases of elderly osteoporotic fractures, guiding perioperative management to alleviate the unfavorable effects of insufficient mechanical loading, high inflammatory levels and pathogen infection. The well-informed pharmacologic and surgical intervention, including treatment with anti-inflammatory drugs and sufficient application of antibiotics, as well as bench-to-bedside strategies for bone augmentation and hardware selection, should be made according to a comprehensive understanding of bone biomechanical properties in addition to the remodeling status of osteoporotic bones, which is necessary for creating proper biological and mechanical environments for bone union and remodeling. Multidisciplinary collaboration will facilitate the improvement of overall osteoporotic care and reduction of secondary fracture incidence.

An Innovative Cerclage Wire Passer

The cerclage wire is an important adjuvant in the management of Orthopaedic and trauma cases and is particularly useful in long bone fractures. It is especially useful for addressing the fractures, especially the comminuted ones with a butterfly fragment. Orthopaedic cerclage Wiring is used as an adjunct to maintain fracture reduction (either temporarily or permanently), while the bone is primarily stabilised by either a plate intramedullary nail or external fixation frame. Multiple cerclage wires provide adjunctive fixation against compressive shear, bending & rotational forces and have been used in traumatology since many years. The aim of this article is to introduce a new year simple low cost instrument named as “Suyash cerclage wire passer”, with excellent outcomes without any major complications to the Orthopaedic community.

从吴楚战争看沈尹戌的政治军事思想

从吴楚战争看沈尹戌的政治军事思想张西庆沈尹戌（？－前５０６年），出身楚国贵族，乃春秋五霸之一的楚庄王曾孙，叶公沈诸梁之父．因封于沈邑为尹，遂以地为姓．楚阳王时任左司马，为当时名将．在澄清楚国内政、抵抗吴国入侵的斗争中曾发挥重大作用，并终以身殒国．一、...

可吸收线治疗四肢粉碎性骨折体会

目的：可吸收线治疗四肢粉碎性骨折手术中应用。方法：对23例四肢粉碎性骨折患者使用可吸收线材料观察。结果：优19例，良4例，优良率100％。结论：可吸收线治疗四肢粉碎性骨折可缩短骨折愈合时问。

Blast-induced ground vibration prediction in granite quarries:An application of gene expression programming,ANFIS,and sine cosine algorithm optimized ANN

Blasting of rocks has intrinsic environmental impacts such as ground vibration,which can interfere with the safety of lives and property.Hence,accurate prediction of the environmental impacts of blasting is imperative as the empirical models are not accurate as evident in the literature.Therefore,there is need to consider some robust predictive models for accurate prediction results.Gene expression programming(GEP),adaptive neuro-fuzzy inference system(ANFIS),and sine cosine algorithm optimized artificial neural network(SCA-ANN)models are proposed for predicting the blast-initiated ground vibration in five granite quarries.The input parameters into the models are the distance from the point of blasting to the point of measurement(D),the weight of charge per delay(W),rock density(q),and the Schmidt rebound hardness(SRH)value while peak particle velocity(PPV)is the targeted output.100 datasets were used in developing the proposed models.The performance of the proposed models was examined using the coefficient of determination(R2)and error analysis.The R2 values obtained for the GEP,ANFIS,and SCA-ANN models are 0.989,0.997,and 0.999,respectively,while their errors are close to zero.The proposed models are compared with an empirical model and are found to outperform the empirical model.

Energy Consumption in Comminution of Mica with Cavitation Abrasive Water Jet

We have studied the efficiency of energy consumption in the comminution of mica powder with cavitation abrasive water jet technology. The energy required to create new surfaces in the comminution of mica powder with cavitation abrasive water jet was calculated,in order to estimate its efficiency of energy consumption. The particle size distribution and the specific surface area were measured by applying a JEM-200CX transmission electron microscope and an Autosorb-1 automatic surface area analyzer. The study results show that the efficiency of energy consumed in creating new surface areas is as high as 2.92%,or 4.94% with the aid of cavitation in the comminution of mica powder. This efficiency will decrease with an increase in the number of comminutions. After three comminutions,the efficien-cies will become 1.91% and 2.29% for comminution without cavitation and with cavitation,respectively. The abrasive water jet technology is an effective way for comminution of mica powder.

An Overview of Mineral Processing in China

The latest progress in mineral processing in China is described. It is also pointed out that the existing technology can not meet the needs of economic development. The combined challenges of poor resources, economical benefits and environmental pollution issues require further research to upgrade the separation efficiency economically. The methods of mineral processing should play a more important part in waste treatment such as wastewater treatment, the remediation of contaminated soil and the recycling of wastes. Biomineral technology will be utilised in the near future.

Application of the fractal theory for evaluating effects of coal comminution by waterjet

Comminution of coal to ultrafine sizes by high-pressure waterjet provides a novel method for preparation of coal-water fuels for next generation,near-zero emission electric power generation.The particle size distribution(PSD)of ground coal is a key parameter in the preparation of slurries as it determines the settling behavior of the particles and viscosity of the coal-water mixture.There are several methods available for representation and evaluation of particle size analysis data.However,fractal theory provides a means by which the entire PSD of comminuted materials can be quantified by using of a specific and exact value.In this paper,a volume-based fractal model was deduced to characterize the PSD of the coal which is ground in a specially designed comminution cell.During the size reduction process,the inlet pressures up to 276 MPa were used.

Pre-treatment of rocks prior to comminution--A critical review of present practices

It has been an established fact that comminution processes, crushing and grinding, are most energy intensive processes which account for more than half of the total energy consumed in mineral industries.Various alternative pre-treatment methods have been tried by experts around the globe. Although these methods yielded positive results in terms of reduction in energy consumption in crushing and particularly, in grinding operations at laboratory scale, their industrial application still remains an unresolved issue and challenge. Present review paper describes each one of these methods along with outcome of earlier studies and issues that need to be addressed through further rigorous experimental investigation.It also suggests the direction in which future studies can be carried out to meet the primary objective of making comminution processes more energy efficient than today they are.

Use of Mineral Liberation Analysis (MLA) in the Characterization of Lithium-Bearing Micas

The capabilities and opportunities of the application of automated mineralogy for the characterization of lithium-bearing zinnwaldite-micas are critically assessed. Samples of a crushed greisen-type ore comprising mostly of quartz, topaz and zinnwaldite (Li-rich mica) were exposed to further comminution by cone crusher and high voltage pulse power fragmentation. Product properties were analyzed by using a Mineral Liberation Analyser (MLA) and the obtained mineralogical and mineral processing relevant parameters were carefully evaluated with special focus on the characteristics of zinnwaldite. The results illustrate that both samples contain a significant quantity of very fine particles that are products of comminution. The modal mineralogy in the different sieve fractions is characterized by the accumulation of minerals of low hardness in the finest fraction and the enrichment of topaz, having a high hardness, in the somewhat larger fractions. Based on the results of mineral association data for zinnwaldite, a displacement of the muscovite-quartz ratio, in comparison to the results of modal mineralogy, was observed by indicating good quartz-zinnwaldite boundary breakage and weak muscovite-zinnwaldite breakage. Liberation as well as mineral grade recovery curves indicate that fraction 1000 to +500 μm is most suitable for beneficiation. The results of this study demonstrate that SEM-based image analysis, such as MLA, can effectively be used to investigate and evaluate phyllosilicate minerals in a fast and precise way. It is shown that the results of MLA investigations, such as modal mineralogy, are in good agreement with other analytical methods such as quantitative X-ray powder diffraction.