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Prediction of Trend between Water Environment Pollution of D Lake and Death Rate of Malignancy in Population 被引量:2
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作者 李龙 吴春松 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2003年第4期420-422,共3页
Grey system analysis method was used to study the correlation between water pollution in D Lake area and death rate of malignancy with death rate of malignancy as effect sequence and a variety of water pollution index... Grey system analysis method was used to study the correlation between water pollution in D Lake area and death rate of malignancy with death rate of malignancy as effect sequence and a variety of water pollution index as factor sequence. On the basis of grey correlation analysis, grey system predication model was established for death rate of malignancy in population in D Lake area including GM (1, N) model for death rate of malignancy [ MR (t+1) =(9.9987E 1+5.0001E 2 +10.8994E 3+1.1114E 4+165.1029) ·e -0.0070t -9.9987E 1-5.0001E 2-10.8994E 3-1.1114E 4 ] and GM (1, 1) model for related factors [ E 1(t+1) =52.1214-46.9468e -0.0058t , E 2(t+1) =4.6114-4.5664e 0.0015t, E 3(t+1) =1.1389-1.1212e 0.0065t , E 4(t+1) = 554.5867-549.8006e 0.0016t ], and the trend of death rate of malignancy from 2000 to 2010 was predicted. 展开更多
关键词 death rate of malignancy grey system water environment pollution
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COVID-19 Pandemic Waves in Italy: An Epidemiological Overview about Infections, Swabs and Death Rates
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作者 Agata Zirilli Francesco Limonti Angela Alibrandi 《Open Journal of Epidemiology》 2022年第3期285-299,共15页
Introduction: On March 11, 2020, the World Health Organization (WHO) declared that the entire World was overrun by a pandemic. Science has managed, in a short time, to characterize a new disease, sequence a new viral ... Introduction: On March 11, 2020, the World Health Organization (WHO) declared that the entire World was overrun by a pandemic. Science has managed, in a short time, to characterize a new disease, sequence a new viral genome, develop diagnostics, produce treatment protocols and establish the efficacy of drugs and vaccines in randomized controlled trials. In this paper we have dealt with different topics regarding the pandemic linked to COVID-19. Objectives: Aim of this paper is to compare the number of deaths attributable to COVID-19, that occurred in the different Italian macro-areas, in the different pandemic waves;we studied the trend of the curves relating to the proportion of deaths to the number of infected in the Italian macro-areas for the pandemic waves and analysed the mortality data, focusing on the Italian context and comparing it with other foreign countries. We examined the data regarding swabs, hospitalizations, home isolation, admissions to intensive care and deaths registered in pandemic period. Results: Geographically, Italy was differently affected by the pandemic. Northern Italy was the most affected area. In comparison with some foreign countries, Italy is one of the nations that paid the most in terms of deaths, due to: delays in understanding the seriousness of the emergency;the slow management in the tracking systems of contagions;the high number of hospitalizations;a corporate organizational system poorly planned. Conclusion: The years 2020 and 2021 have been dramatic and unprecedented. The year 2021 was the year of redemption, where, despite social, economic and health difficulties, thanks to mass vaccination, we were able to give a real strong response to the pandemic. Trust in science has led to a drastic decrease in mortality throughout the world. 展开更多
关键词 Statistical Analysis Comparisons SWABS HOSPITALIZATIONS death rates
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An SIRS Epidemic Model with Pulse Vaccination, Birth Pulse and Logistic Death Rate
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作者 GAO JIAN-ZHONG ZHANG TAI-LEI 《Communications in Mathematical Research》 CSCD 2019年第3期247-263,共17页
In this paper, we propose an SIRS epidemic model with pulse vaccination, birth pulse and Logistic death rate. By using the stroboscopic map of a discrete dynamical system, the disease-free periodic solution (DFPS for ... In this paper, we propose an SIRS epidemic model with pulse vaccination, birth pulse and Logistic death rate. By using the stroboscopic map of a discrete dynamical system, the disease-free periodic solution (DFPS for short) of the model under pulse vaccination and birth pulse is obtained. Based on the Floquet theory and comparison theorem of impulsive differential equations, the global asymptotic stability of the DFPS is given, and sufficient conditions for the permanence of the model are obtained. In addition, numerical simulations are done to confirm our theoretical results. 展开更多
关键词 LOGISTIC death rate BIRTH PULSE THRESHOLD value global stability PERMANENCE
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Aspirin Helped Reduce Heart Attack Death Rate
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作者 柳青 《当代外语研究》 2001年第4期1-2,共2页
本刊曾经多次刊登文章盛赞百年老药阿斯匹林。去年第10期就载文称阿斯匹林能抗前列腺癌,今又消息文称,阿斯匹林能减少心脏病人的死亡率。百年老药.青春犹在,至今仍能让人们不断发现其新的功效!本文除了传递了有关阿斯匹林的新信息之外... 本刊曾经多次刊登文章盛赞百年老药阿斯匹林。去年第10期就载文称阿斯匹林能抗前列腺癌,今又消息文称,阿斯匹林能减少心脏病人的死亡率。百年老药.青春犹在,至今仍能让人们不断发现其新的功效!本文除了传递了有关阿斯匹林的新信息之外,以下观点,也让我们耳目一新: Even as we live and practice medicine in an era of high technology,we mustalways remember that widespread application of relatively low technology,efficacious(有效的;灵验的),and cost-effective(有成本效益的,值得花费的)therapies is often the way we help most of our patients and provide the greatestaggregate(集合的;聚合的)benefit for the broader population. 上句是否可以这样译: 即使我们生活、就医在一个高科技的时代,但是,我们仍必须一直牢记:科技含量相对较低却又广为应用的东西,其灵验而又具有成本效益的治疗常常是我们帮助大多数患者,为广大群众提供最大利益的途径。 上句的难点在于:如何理解provide the greatest aggregate benefit for thebroader population的主语。 展开更多
关键词 阿斯匹林 Aspirin Helped Reduce Heart Attack death rate
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Infant mortality rate in Al-Ramadi province from 2000 through 2010, retrospective study 被引量:2
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作者 Hammodi F. Aljumaily Muhammed M. Al-Ani Muhammed M. Hantush 《Health》 2013年第2期292-297,共6页
Objectives: To determine the IMR in Al-Ramadi province, the center of Al-Anbar Governorate, Western Iraq, from 2000-2010 with rate comparison of the three different stages of that period. Methods: Data collected from ... Objectives: To determine the IMR in Al-Ramadi province, the center of Al-Anbar Governorate, Western Iraq, from 2000-2010 with rate comparison of the three different stages of that period. Methods: Data collected from the birth and death certificate center in Al-Ramadi province, Western Iraq, included;name, age, sex, residence, date of birth and death, in three different stages (the first stage 2000-2002, the second stage 2003-2007, and the third stage 2008-2010) in a study period from July to December, 2010. The IMRs were analyzed and compared with other studies. Results: The IMR of the last 3 years of sanction was 54.3/1000, 55.7/1000 and 50.6/1000 respectively, this rate had been increased in the war and violence period to reach its maximum rate 58.6/1000 in 2006, then decreased to reach its minimum rate 44.5/1000 in 2008. Approximately two-third of deaths occurred during the neonatal period and one third in the post neonatal period. Males had higher IMR than females, and rural residence higher than urban. Conclusion: Infant mortality rate is still high in Al-Ramadi province, since the American invasion (2003-2007), when compared with other developing countries. This study found increase of IMR in Al-Ramadi province during that period more than other studied years. 展开更多
关键词 MORTALITY rate BIRTH death CERTIFICATE
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Early detection of sudden cardiac death by using classical linear techniques and time-frequency methods on electrocardiogram signals 被引量:2
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作者 Elias Ebrahimzadeh Mohammad Pooyan 《Journal of Biomedical Science and Engineering》 2011年第11期699-706,共8页
Early detection of sudden cardiac death may be used for surviving the life of cardiac patients. In this paper we have investigated an algorithm to detect and predict sudden cardiac death, by processing of heart rate v... Early detection of sudden cardiac death may be used for surviving the life of cardiac patients. In this paper we have investigated an algorithm to detect and predict sudden cardiac death, by processing of heart rate variability signal through the classical and time-frequency methods. At first, one minute of ECG signals, just before the cardiac death event are extracted and used to compute heart rate variability (HRV) signal. Five features in time domain and four features in frequency domain are extracted from the HRV signal and used as classical linear features. Then the Wigner Ville transform is applied to the HRV signal, and 11 extra features in the time-frequency (TF) domain are obtained. In order to improve the performance of classification, the principal component analysis (PCA) is applied to the obtained features vector. Finally a neural network classifier is applied to the reduced features. The obtained results show that the TF method can classify normal and SCD subjects, more efficiently than the classical methods. A MIT-BIH ECG database was used to evaluate the proposed method. The proposed method was implemented using MLP classifier and had 74.36% and 99.16% correct detection rate (accuracy) for classical features and TF method, respectively. Also, the accuracy of the KNN classifier were 73.87% and 96.04%. 展开更多
关键词 SUDDEN CARDIAC death Heart rate Variability TIME-FREQUENCY Transform ELECTROCARDIOGRAM Signal Linear Processing
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振荡频率对曼氏无针乌贼成体死亡率及生存状态的影响 被引量:1
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作者 周珊珊 周永东 +6 位作者 李哲 欧阳洪 镇小蔓 梁君 陈俊琳 陈佳怡 徐开达 《水产学报》 CAS CSCD 北大核心 2024年第2期187-196,共10页
为提高曼氏无针乌贼增殖放流运输过程的存活率,在实验室条件下研究了0、60、100、120、140和160 r/min振荡频率对成体曼氏无针乌贼死亡率、乳酸、糖原含量及酶活性的影响。结果显示,除160 r/min死亡率略有下降外,其他组随着频率的增高... 为提高曼氏无针乌贼增殖放流运输过程的存活率,在实验室条件下研究了0、60、100、120、140和160 r/min振荡频率对成体曼氏无针乌贼死亡率、乳酸、糖原含量及酶活性的影响。结果显示,除160 r/min死亡率略有下降外,其他组随着频率的增高死亡率升高,频率120、140 r/min时死亡率最高为91.7%,显著高于0、60、100 r/min处理组。死亡时间主要分布在振荡后的4~8 h,频率越低乌贼出现死亡的时间越晚,160 r/min率先在2 h出现死亡个体。除个别组出现波动外,随着频率的增大,两种组织(肌肉、肝脏)的糖原含量降低,而乳酸含量增大,140 r/min处理组糖原、乳酸含量与对照组间差异显著。除60 r/min处理组外,随着频率的增加,肝脏组织中的谷丙转氨酶(ALT)、谷草转氨酶(GOT)活性降低,超氧化物歧化酶(SOD)活性增加,且120、140、160 r/min处理组3种酶活性与其他组间差异显著。碱性磷酸酶(ALP)活性随着频率的增加而升高,140和160r/min处理组与其他组间差异显著。乌贼死亡率与SOD、肌肉乳酸含量、ALP之间极显著正相关,与肌肉糖原含量、GOT和ALT活性、消化腺糖原含量之间极显著负相关。研究表明,频率显著影响乌贼的存活率,能量耗尽和肝脏损伤可能是乌贼运输过程高死亡率的主要原因,运输过程建议振荡频率小于100 r/min且运输时间小于3 h,尽量避免较大程度的晃动。本研究可为曼氏无针乌贼成体的增殖放流运输过程提供技术支撑。 展开更多
关键词 曼氏无针乌贼 振荡频率 喷墨 死亡率 糖原 乳酸
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Kinetics of aggregation growth with competition between catalyzed birth and catalyzed death
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作者 王海锋 林振权 高艳 《Chinese Physics B》 SCIE EI CAS CSCD 2008年第4期1490-1500,共11页
An aggregation growth model of three species A, B and C with the competition between catalyzed birth and catalyzed death is proposed. Irreversible aggregation occurs between any two aggregates of the like species with... An aggregation growth model of three species A, B and C with the competition between catalyzed birth and catalyzed death is proposed. Irreversible aggregation occurs between any two aggregates of the like species with theconstant rate kernels In(n = 1,2, 3). Meanwhile, a monomer birth of an A species aggregate of size k occurs under the catalysis of a B species aggregate of size j with the catalyzed birth rate kernel K(k, j) = Kkj^v, and a monomer death of an A species aggregate of size k occurs under the catalysis of a C species aggregate of size j with the catalyzed death rate kernel L(k, j) = Lkj^v, whcre v is a parameter reflecting the dependence of the catalysis reaction rates of birth and death on the size of catalyst aggregate. The kinetic evolution behaviours of the three species are investigated by the rate equation approach based on the mean-field theory. The form of the aggregate size distribution of A species ak (t) is found to be dependent crucially on the competition between the catalyzed birth and death of A species, as well as the irreversible aggregation processes of the three species: (i) In the v 〈 0 case, the irreversible aggregation dominates the process, and ak(t) satisfies the conventional scaling form; (2) In the v ≥ 0 casc, the competition between the catalyzed birth and death dominates the process. When the catalyzed birth controls the process, ak(t) takes the conventional or generalized scaling form. While the catalyzed death controls the process, the scaling description of the aggregate size distribution breaks down completely. 展开更多
关键词 kinetic scaling behaviour aggregation growth catalyzed birth and death rate equation
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Analysis of Cause of Death in Inner Mongolia of China, 2008-2014
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作者 Shuli Xing Zhiqiang Sun +10 位作者 Maolin Du Xuesen Shi Hairong Zhang Zhanlong Wang Xiaoyan Zhang Zhihui Hao Zhuang Su Ying Yang Rong Liu Yueling Hu Juan Sun 《Open Journal of Epidemiology》 2017年第1期10-17,共8页
Objective: The aim of our study was to analyze the character of cause of death in Inner Mongolia of China from 2008 to 2014. Methods: We collected data from monitoring points of the Death Registry System (DRS) in Inne... Objective: The aim of our study was to analyze the character of cause of death in Inner Mongolia of China from 2008 to 2014. Methods: We collected data from monitoring points of the Death Registry System (DRS) in Inner Mongolia. We calculated the mortality rates by gender, year and age-specific. We calculated the proportion, the mortality rate and potential years of life lost (PYLL) of various system deaths. Results: During the period 2008-2014, the average crude mortality rate of all cause of death was 539.33/105. The mortality rate increased semilogarithm linearly with age. The top four system deaths were circulatory system, neoplasm, respiratory system and injury. In 2014, the mortality rates of circulatory system were increased and the mortality rates of certain infectious and parasitic diseases, neoplasms, respiratory system, genitourinary system and injury were decreased compared to those in 2008. Conclusion: Through analysis the indicators of proportion, the mortality rate and PYLL indicated that health status of a population in Inner Mongolia was at a better level. 展开更多
关键词 CAUSE of death MORTALITY rate PYLL
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运动后心率恢复与心源性猝死风险的相关性:一项队列研究的Meta分析
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作者 王晨阳 徐鹏 +3 位作者 郭治荣 王冬颖 李俊峡 曹雪滨 《中国循证心血管医学杂志》 2024年第4期398-402,共5页
目的通过Meta分析,综合分析运动后心率恢复(HRR)与心源性猝死(SCD)之间的关系。方法基于PubMed、Embase和Web of Science数据库,进行截至2024年1月2日的文献检索。队列研究关注于HRR和SCD间的风险关系,通过风险比(HR)及95%可信区间(CI)... 目的通过Meta分析,综合分析运动后心率恢复(HRR)与心源性猝死(SCD)之间的关系。方法基于PubMed、Embase和Web of Science数据库,进行截至2024年1月2日的文献检索。队列研究关注于HRR和SCD间的风险关系,通过风险比(HR)及95%可信区间(CI)进行评估。统计学分析采用Stata 12.0软件。结果纳入6项研究。固定效应模型(I^(2)=41.8%,P=0.112)的汇总结果显示:与心率恢复慢相比,心率恢复快人群发生SCD风险更低(HR=0.74,95%CI:0.64~0.86,P<0.001)。大多数亚组分析中都观察到了持续结果。排除一项研究并不影响总体结果[HR(95%CI):0.66(0.55,0.79)~0.76(0.65,0.88)]。Egger检验未发现明显的发表偏倚(P=0.059)。结论心率恢复较慢会增加普通人群发生SCD的风险。因此,HRR可能是临床实践中预防SCD的一个潜在靶点。 展开更多
关键词 心源性猝死 运动后心率恢复 荟萃分析 风险相关性
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Exploring the Association between Climate Change and Human Development: A Visual Analytics Study
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作者 Dongli Zhang Wullianallur Raghupathi Viju Raghupathi 《Atmospheric and Climate Sciences》 2024年第4期368-395,共28页
This study explores the complex relationship between climate change and human development. The aim is to understand how climate change affects human development across countries, regions, and the global population. Vi... This study explores the complex relationship between climate change and human development. The aim is to understand how climate change affects human development across countries, regions, and the global population. Visual analytics were used to examine the impact of various climate change indicators on different aspects of human development. The study highlights the urgent need for climate change action and encourages policymakers to make decisive moves. Climate change adversely affects numerous aspects of daily life, leading to significant consequences that must be addressed through policy changes and global governance recommendations. Key findings include that regions with higher CO2 emissions experience a significantly higher incidence of life-threatening diseases compared to regions with lower emissions. Additionally, higher CO2 emissions correlate with consistent death rates. Increased pollution exposure is associated with a higher prevalence of life-threatening diseases and higher rates of malnutrition. Moreover, greater mineral depletion is linked to more frequent life-threatening diseases, suggesting that industrialization contributes to adverse health effects. These results provide valuable insights for policy and decision-making aimed at mitigating the impact of climate change on human development. 展开更多
关键词 Air Pollution Climate Change CO2 Emissions death rate GDP Human Development Visual Analytics
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The Significance of Angiotensin Converting Enzyme Inhibitor or Angiotensin II Receptor Blocker Use in Sudden Cardiac Death
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作者 Makoto Onodera Satoshi Kikuchi +2 位作者 Yasuhisa Fujino Yoshihiro Inoue Yuji Fujita 《International Journal of Clinical Medicine》 2017年第8期496-503,共8页
Objectives: To investigate the relationship between the use of angiotensin converting enzyme (ACE) inhibitor or angiotensin II receptor blocker (ARB) and hyperkalemia in patients diagnosed with sudden cardiac death. M... Objectives: To investigate the relationship between the use of angiotensin converting enzyme (ACE) inhibitor or angiotensin II receptor blocker (ARB) and hyperkalemia in patients diagnosed with sudden cardiac death. Methods: We examined oral ACE inhibitor or ARB use among cardiopulmonary arrest patients brought by ambulance to our emergency room during a 5-year period from January 2012 to December 2016. The cause of death was determined to be sudden cardiac death, despite temporary return of spontaneous circulation after starting cardiopulmonary resuscitation. Subjects were dichotomized into 2 groups, those taking and those not taking an ACE inhibitor or ARB. Variables determined retrospectively included serum potassium, estimated glomerular filtration rate as an index of kidney function and time from cardiopulmonary arrest to return of spontaneous circulation. The Mann-Whitney U-test was used to compare continuous data, and the chi-square test to compare categorical data between groups. The results are expressed as the median plus range. Statistical significance was assumed at p Results: Thirty-five patients met the inclusion criteria. The mean age was 77.1 years (range, 35 - 93 years), and there were 26 males and 9 females. Eleven subjects were ACE inhibitor or ARB users, and 24 were non-users. The serum potassium level was significantly higher in users than non-users (median, 6.2 mEq/L (range, 4.5 - 10.0) vs. 5.2 mEq/L (range, 3.6 - 8.3);p = 0.001). The estimated glomerular filtration rate was significantly lower in users than non-users (median, 25.1 mL/min/1.73 m2 (range, 4.6 - 60.3) vs. 46.9 mL/min/1.73 m2 (range, 19.8 - 97.1);p = 0.009). There was no significant difference in time from cardiopulmonary arrest to return of spontaneous circulation between the 2 groups (median, 24 minutes (range, 3 - 111) vs. 29 minutes (range, 10 - 54);p = 0.355). Conclusion: It is possible that hyperkalemia induced by ACE inhibitor or ARB use is a cause of sudden cardiac death, especially in patients with chronic kidney disease. 展开更多
关键词 ANGIOTENSIN CONVERTING Enzyme Inhibitors ANGIOTENSIN II Receptor BLOCKERS Glomerular Filtration rate HYPERKALEMIA SUDDEN Cardiac death
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2016-2021年北京市5岁以下儿童死亡变化趋势及死因研究
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作者 李东阳 李一辰 《首都公共卫生》 2024年第1期9-12,共4页
目的 分析2016-2021年北京市5岁以下儿童死亡率(U5MR)变化趋势及主要死因,为制定、调整干预策略提供依据。方法 提取北京市妇幼保健网络信息系统中2016-2021年5岁以下儿童死亡监测数据,对北京市U5MR和不同年龄组死亡率变化趋势及主要死... 目的 分析2016-2021年北京市5岁以下儿童死亡率(U5MR)变化趋势及主要死因,为制定、调整干预策略提供依据。方法 提取北京市妇幼保健网络信息系统中2016-2021年5岁以下儿童死亡监测数据,对北京市U5MR和不同年龄组死亡率变化趋势及主要死因进行回顾性分析。结果 2016-2021年北京市U5MR呈下降趋势,2021年下降至2.24‰,已达到国际领先水平。5岁以下儿童各年龄组中,新生儿死亡率(NMR)下降速度最快,年度变化百分比(APC)为-8.98%(95%CI:-13.14%~-5.59%),是2016-2021年北京市U5MR下降的主要原因;而1~<5岁儿童死亡率呈上升趋势(APC=13.50%,95%CI:1.06%~27.51%)。2016-2021年早产或低出生体重(APC=-14.00%,95%CI:-23.51%~-6.38%)和其他新生儿疾病死亡率(APC=-25.91%,95%CI:-44.69%~-12.43%),呈下降趋势;意外伤害死亡率呈上升趋势(APC=12.34%,95%CI:5.11%~19.72%)。2021年主要死因中,远郊地区先天异常、意外伤害、早产或低出生体重和出生窒息死亡率均高于城市地区。2016-2021年,城市地区和远郊地区早产或低出生体重死亡率均呈下降趋势,城市地区出生窒息和远郊地区其他新生儿病死亡率呈下降趋势;城市地区意外伤害和肺炎死亡率呈上升趋势。结论 北京市在降低NMR以及降低早产或低出生体重和其他新生儿病等疾病死亡率方面成果显著,但同时还应重视意外伤害、先天异常和出生窒息等主要死因防控,并加强对1~<5岁儿童群体的关注。 展开更多
关键词 5岁以下儿童死亡率 新生儿死亡率 死亡原因 人群监测
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西非国家2009年与2019年居民健康预期寿命及死亡状况比较及对中非卫生合作的启示
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作者 牛璐 曾梦 《广西医科大学学报》 CAS 2024年第5期762-768,共7页
目的:比较西非国家2009年和2019年各国居民健康预期寿命及死亡状况,为后续规划与布局新时期的中非健康卫生合作,开展精准的援助项目提供数据支持。方法:基于2019年全球疾病负担研究(GBD 2019),收集和比较西非15个国家2009年和2019年健... 目的:比较西非国家2009年和2019年各国居民健康预期寿命及死亡状况,为后续规划与布局新时期的中非健康卫生合作,开展精准的援助项目提供数据支持。方法:基于2019年全球疾病负担研究(GBD 2019),收集和比较西非15个国家2009年和2019年健康预期寿命,传染病、母婴疾病和营养缺乏性疾病,慢性病及伤害的死亡变化情况。结果:与2009年相比,2019年西非15个国家的居民健康预期寿命有所增加,其中佛得角的居民健康预期寿命最高(64.6岁),几内亚比绍最低(53.6岁);2019年西非15个国家传染病、母婴疾病和营养缺乏性疾病的标化死亡率较2009年均显著下降;佛得角、布基纳法索和冈比亚的慢性病标化死亡率有所增加;布基纳法索和马里的伤害标化死亡率有所增加,尼日尔保持不变;其他国家的慢性病和伤害标化死亡率有所下降。与2009年相比,西非国家2019年传染病、母婴和营养缺乏性疾病死因占比均有所下降,但在多数国家的死因占比依然超过50%;其中,佛得角是唯一慢性病死因占比多于传染病、母婴和营养缺乏性疾病(72.2%vs.17.9%)的国家;2019年孕产妇疾病、麻疹和艾滋病等传染病死因顺位较2009年下降明显,而多种慢性病(如糖尿病、慢性肾脏疾病)的死因顺位有所上升。结论:在过去10年间,西非国家在国民健康状况方面取得了一些进步,但健康预期寿命仍相对偏低,面临着传染病和慢性非传染病双重威胁,而伤害死亡率也依然较高;中非健康卫生合作的援助内容和方式应根据受援国情况,因地制宜、精准施策。 展开更多
关键词 健康预期寿命 死亡率 死因 西非国家
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重金属Pb^(2+)、Cd^(2+)、Cr^(6+)对洞庭青鲫仔鱼急性毒性、细胞凋亡及组织损伤的影响
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作者 类延菊 戴佳 +3 位作者 张琴 张运生 杨品红 邵立业 《湖南文理学院学报(自然科学版)》 CAS 2024年第3期58-63,71,共7页
研究重金属Pb^(2+)、Cd^(2+)、Cr^(6+)对洞庭青鲫(Carassius auratus indigentiaus)仔鱼的毒性效应。选择不同浓度的Pb^(2+)、Cd^(2+)、Cr^(6+)处理洞庭青鲫仔鱼,分别在实验的0、24、48、72、96 h观察重金属离子对仔鱼死亡率的影响。选... 研究重金属Pb^(2+)、Cd^(2+)、Cr^(6+)对洞庭青鲫(Carassius auratus indigentiaus)仔鱼的毒性效应。选择不同浓度的Pb^(2+)、Cd^(2+)、Cr^(6+)处理洞庭青鲫仔鱼,分别在实验的0、24、48、72、96 h观察重金属离子对仔鱼死亡率的影响。选择96 h低死亡率重金属浓度处理组(2 mg·L^(-1)Pb^(2+)、0.125 mg·L^(-1)Cd^(2+)、5 mg·L^(-1)Cr6+),观察各重金属对洞庭青鲫仔鱼鳃组织损伤及细胞凋亡的影响。结果表明:(1)Pb^(2+)、Cd^(2+)、Cr^(6+)对洞庭青鲫仔鱼的96-LC_(50)分别为39.5、0.39、16.38 mg⋅L^(-1),安全浓度分别为3.945、0.039、1.638 mg·L^(-1)。急性毒性由强至弱依次为Cd^(2+)>Pb^(2+)>Cr^(6+);(2)5 mg·L^(-1)Cr^(6+)处理组洞庭青鲫仔鱼96 h死亡率为37%,仔鱼鳃组织产生严重损伤,包括细胞纹理变得疏松,色素细胞大量增加,纤毛脱落,大量细胞空泡化,巨噬细胞增多,结缔组织发生糜烂坏死等。2 mg⋅L^(-1)Pb^(2+)和0.125 mg⋅L^(-1)Cd^(2+)处理组洞庭青鲫仔鱼96 h死亡率分别为16%和58%,仔鱼鳃组织出现轻微损伤,色素细胞少量增加,少量细胞出现空泡化;(3)2 mg⋅L^(-1)Pb^(2+)、0.125 mg⋅L^(-1)Cd^(2+)、5 mg⋅L^(-1)Cr^(6+)三个处理组的洞庭青鲫仔鱼鳃部发生细胞凋亡,并且Pb^(2+)处理组鳃部细胞凋亡最严重。综上所述,Pb^(2+)、Cd^(2+)、Cr^(6+)对洞庭青鲫仔鱼具有较强的毒性,但是各重金属处理组死亡率与组织损伤、细胞凋亡无显著的相关性,不同重金属导致洞庭青鲫死亡的机制可能不一样。 展开更多
关键词 重金属 洞庭青鲫 死亡率 组织损伤 细胞凋亡
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2009-2023年天津市某儿童医院住院儿童死亡病例分析
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作者 程方 赵旻鹏 +1 位作者 张冉冉 李丽静 《医学新知》 CAS 2024年第8期861-870,共10页
目的分析2009—2023年天津市某儿科医院住院儿童死亡病例特点。方法收集天津市某儿童医院2009—2023年住院儿童的病案首页信息,分析2009—2013年、2014—2018年、2019—2023年三个时间段死亡病例的性别、年龄、疾病系统及死亡病种情况... 目的分析2009—2023年天津市某儿科医院住院儿童死亡病例特点。方法收集天津市某儿童医院2009—2023年住院儿童的病案首页信息,分析2009—2013年、2014—2018年、2019—2023年三个时间段死亡病例的性别、年龄、疾病系统及死亡病种情况。结果2009—2023年,住院患儿共678145例,其中876例死亡,死亡率为0.13%;三个时间段的死亡率分别为0.28%、0.16%、0.06%,整体呈递减趋势(χ^(2)=383.962,P<0.01)。男性儿童死亡率(0.12%)显著低于女性儿童死亡率(0.15%)(χ^(2)=303.785,P<0.01)。婴儿期死亡人数最多(263例),青春期死亡人数最少(61例)。死亡疾病系统顺位在三个时间段的变化方面,循环系统疾病从第六位上升至第三位,肿瘤从第九位上升至第六位,先天性畸形、变形和染色体异常从第三位降至第八位。前十位死亡病种中,重症肺炎在三个时间段中均排名第一;急性淋巴细胞白血病顺位由2009—2013年的第九位上升至2019—2023年的第三位。新生儿期排名第一的死亡病种为新生儿呼吸衰竭,婴儿期、幼儿期、学龄前期及学龄期排名第一的死亡病种均为重症肺炎,青春期排名第一的死亡病种为海绵窦脓肿。结论2009—2023年间天津市住院儿童死亡率明显下降,儿科临床和预防工作应继续重点关注婴儿期的重症肺炎、脓毒血症患儿,以及海绵窦脓肿等病种,同时应加强对循环系统、某些传染病和寄生虫病、意外伤害、恶性肿瘤的预防和控制,以有效降低住院患儿死亡率。 展开更多
关键词 住院儿童 死亡病例 死亡率 死亡病种
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急性食管坏死研究进展
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作者 马兴瑶 邹金铭 赵贵森 《食管疾病》 2024年第2期124-129,共6页
急性食管坏死(acute esophageal necrosis,AEN)主要累及食管中下段,患者常表现为上消化道出血,以食管远端黏膜变黑为典型特征,故有“黑色食管”(black esophagus)之称。AEN与恶性肿瘤、糖尿病、高血压和心血管疾病等常见疾病密切相关,... 急性食管坏死(acute esophageal necrosis,AEN)主要累及食管中下段,患者常表现为上消化道出血,以食管远端黏膜变黑为典型特征,故有“黑色食管”(black esophagus)之称。AEN与恶性肿瘤、糖尿病、高血压和心血管疾病等常见疾病密切相关,是老年重症患者常见的致命性并发症,相关死亡率高达30%以上。本文对AEN的流行病学、病因学、发病机制、临床诊治以及法医学尸检和死因分析等方面的新进展进行综述,供临床诊治及法医学鉴定参考。 展开更多
关键词 急性食管坏死 上消化道出血 死亡率 死亡原因
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2011年-2020年苏州工业园区5岁以下儿童死亡监测分析
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作者 孙雨玥 王丹丹 +3 位作者 树明华 周慧 陈小芳 吴蕾 《中国血液流变学杂志》 CAS 2024年第2期284-289,共6页
目的了解苏州工业园区2011年—2020年5岁以下儿童死亡率(U5MR)变化趋势及其流行病学特征,为制定妇幼卫生政策提供参考依据。方法收集2011年—2020年园区各级医疗机构上报的5岁以下儿童死亡个案,采用SAS 9.4软件对资料进行统计描述和统... 目的了解苏州工业园区2011年—2020年5岁以下儿童死亡率(U5MR)变化趋势及其流行病学特征,为制定妇幼卫生政策提供参考依据。方法收集2011年—2020年园区各级医疗机构上报的5岁以下儿童死亡个案,采用SAS 9.4软件对资料进行统计描述和统计推断。结果U5MR、新生儿(<28 d)死亡率(NMR)、婴儿(<1岁)死亡率(IMR)和1~4岁儿童死亡率分别为2.82‰、1.51‰、2.18‰、0.64‰;U5MR(χ^(2)趋势=0.24,P>0.05)变化较小,1~4岁儿童死亡率逐年呈缓慢下降趋势(χ^(2)趋势=7.41,P=0.0065);新生儿、婴儿(28 d~1岁)、1~4岁儿童死亡占比分别为53.50%、23.89%、22.61%;5岁以下儿童主要死因前三位:早产或低出生体重(16.24%)、先天性心脏病(11.78%)、意外窒息(7.96%)。结论园区5岁以下儿童死亡率控制在一个较低水平范围内;通过继续提升辖区内各医疗卫生机构产/儿科水平、完善妇幼保健服务网络、加强孕期及围产期保健管理、继续规范实施出生缺陷三级预防工作等手段对早产儿或低出生体重儿和先天性心脏病予以重点干预。 展开更多
关键词 5岁以下儿童 死亡率 死因
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2018—2022年某综合性三甲医院住院死亡病例分析
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作者 邵丹婷 濮晓燕 +2 位作者 羊晓芳 赵孙峰 郭胜才 《中国医院统计》 2024年第3期175-178,184,共5页
目的 分析2018—2022年某综合性三甲医院住院患者死亡病例特征,为科学合理配置医疗资源,加强医疗质量管理提供参考。方法 从该院病案信息系统中提取2018年1月1日至2022年12月31日的所有出院患者信息,对出院患者和死亡病例总数、年龄、... 目的 分析2018—2022年某综合性三甲医院住院患者死亡病例特征,为科学合理配置医疗资源,加强医疗质量管理提供参考。方法 从该院病案信息系统中提取2018年1月1日至2022年12月31日的所有出院患者信息,对出院患者和死亡病例总数、年龄、性别分布以及疾病诊断等,采用Excel 2007和SPSS 18.0软件进行数据整理和统计分析。结果 675例死亡病例中,男性病例443例(65.63%),女性232例(34.37%),住院患者病死率0.64%;死亡原因居前3位的疾病为循环系统疾病、呼吸系统疾病、肿瘤,分别占总死亡病例数的28.44%、28.30%和27.56%;死亡病例男女性别比1.91∶1,病死率男性高于女性,差异有统计学意义(χ2=46.068,P<0.001)。年龄越大,病死率越高,50岁以上病死率迅速上升。结论 医院住院患者病死率总体较低,老年人是该院的死亡高危人群,循环系统疾病、恶性肿瘤和呼吸系统疾病是最主要的死亡原因。在医疗工作中,应根据患者年龄、性别、死亡高发病种等特点,科学合理配置医疗资源,降低住院患者病死率。 展开更多
关键词 住院患者 死亡病例 病死率 疾病构成 统计分析
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2019—2022年六盘水市居民死因监测数据分析
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作者 包红艳 林江丽 张元安 《临床医学研究与实践》 2024年第21期5-8,共4页
目的分析2019—2022年六盘水市居民死因监测数据,为当地制定医疗卫生政策以及强化疾病预防控制措施提供参考依据。方法收集人口死亡信息登记管理系统中六盘水市死亡时间为2019年1月至2022年12月的所有个案资料,应用Excel2019软件整理数... 目的分析2019—2022年六盘水市居民死因监测数据,为当地制定医疗卫生政策以及强化疾病预防控制措施提供参考依据。方法收集人口死亡信息登记管理系统中六盘水市死亡时间为2019年1月至2022年12月的所有个案资料,应用Excel2019软件整理数据,应用Jamovi2.3.13软件进行数据统计分析,采用描述流行病学方法分析死亡率、死因顺位、期望寿命等。结果2019—2022年六盘水市居民中,男性的粗死亡率、标化死亡率高于女性(P<0.01)。六盘水市居民前7位死亡原因依次为脑血管疾病、恶性肿瘤、心脏病、损伤和中毒、呼吸系统疾病、消化系统疾病及内分泌、营养和代谢性疾病。2019—2022年六盘水市居民人均期望寿命分别为74.50、75.40、75.53、74.80岁。结论2019—2022年六盘水市居民主要死因为慢性非传染性疾病,应建立政府主导、多部门配合、全民参与的慢性病防控体系以降低慢性病死亡率。 展开更多
关键词 六盘水市居民 死因监测 死亡率 期望寿命 健康水平
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