期刊文献+
共找到1篇文章
< 1 >
每页显示 20 50 100
Amphiphilic poly(ethylene glycol)-b-poly(ethylene brassylate)copolymers: One-pot synthesis, self-assembly, and controlled drug release 被引量:2
1
作者 Jiu-Cun Chen Jun-Zhi Li +1 位作者 Jian-Hua Liu Li-Qun Xu 《Chinese Chemical Letters》 SCIE CAS CSCD 2015年第10期1319-1321,共3页
A set of amphiphilic poly(ethylene glycol)-b-poly(ethylene brassylate)(PEG-b-PEB) copolymers based on the PEB hydrophobic block was first synthesized by ring-opening polymerization of ethylene brassylate with an... A set of amphiphilic poly(ethylene glycol)-b-poly(ethylene brassylate)(PEG-b-PEB) copolymers based on the PEB hydrophobic block was first synthesized by ring-opening polymerization of ethylene brassylate with an organic catalyst. The EB/PEG molar ratios and reaction times were adjusted to achieve different chain lengths of PEB. Block copolymers that were characterized by1 H NMR and GPC could selfassemble into multimorphological aggregates in aqueous solution, which were characterized by DLS and TEM. The hydrophobic doxorubicin(DOX) was chosen as a drug model and successfully encapsulated into the nanoparticles. The release kinetics of DOX were investigated. 展开更多
关键词 Poly(ethylene brassylate) Self-assembly Nanoparticles Controlled drug release
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部