Expert consensus on the technical specifications of the in vitro skin penetration test of cosmetic product by Franz diffusion cell

Background:Diffusion cell test is one of the most commonly used in vitro model to detect the percutaneous absorption of cosmetic ingredients.Although PRC State Administration of Quality Supervision and Quarantine has issued the guideline for the in vitro test method for the percutaneous absorption of drug molecules,there is still a lack of guideline for the percutaneous absorption test of cosmetic components.Objective:In order to improve the standardized level and make the in vitro percutaneous absorption test of cosmetic ingredients more comparable,based on the international and domestic experience,Transdermal Drug Delivery Committee of the World Federation of Chinese Medicine Societies organized the experts to discuss and formed this consensus as reference for the percutaneous absorption test of cosmetic components.Materials and Methods:To standardize the in vitro diffusion cell test technique for transdermal penetration of functional cosmetic ingredients,the Transdermal Drug Delivery Professional Committee of the World Federation of Societies of Traditional Chinese Medicine has organized many discussions among experts.

基于Design-Expert的电链锯锯齿结构参数优化

为提高电链锯的锯切效率,对电链锯锯齿的齿形结构参数进行研究,以单位锯切功为电链锯锯切效率的衡量指标,通过对电链锯锯切过程的仿真研究,得出不同结构锯齿的单位锯切功。以电链锯锯齿中的外形前角、侧刃楔角和顶刃楔角等结构参数作为影响因子,采用Box-Benhnken中心组合试验方法设计多因素正交试验,使用Design-expert软件进行数据分析得出最优齿形结构参数组合。研究结果表明,所选取的齿形结构参数对单位锯切功影响程度由大到小顺序依次为外形前角、侧刃楔角、顶刃楔角,并获得最优齿形结构参数组合,外形前角为10.92°、侧刃楔角为45.7°、顶刃楔角为45.41°。

EXPERT SYSTEM FOR COMPREHENSIVE ASSESSMENT TOBRIDGE SERVICE PROPERTY USING FUZZY THEORY

In this paper, based on consultation to tens of bridge exberts and a vast amount of investigation and study, experts knowledge on bridge assessment has been sorted out. A new concept Damage Value (DV) is put forward to measure bridge damage, and Fuzzy theory is used to create comprehensive Fuzzy system to assess bridge service property. The setup of an experts system for bridge assessment is tried as well. This system is programmed in Turbo C 2.0 and has been run successfully at IBM-PC (AT/XT).

Expert Experience and Data-Driven Based Hybrid Fault Diagnosis for High-SpeedWire Rod Finishing Mills

The reliable operation of high-speed wire rod finishing mills is crucial in the steel production enterprise.As complex system-level equipment,it is difficult for high-speed wire rod finishing mills to realize fault location and real-time monitoring.To solve the above problems,an expert experience and data-driven-based hybrid fault diagnosis method for high-speed wire rod finishing mills is proposed in this paper.First,based on its mechanical structure,time and frequency domain analysis are improved in fault feature extraction.The approach of combining virtual value,peak value with kurtosis value index,is adopted in time domain analysis.Speed adjustment and side frequency analysis are proposed in frequency domain analysis to obtain accurate component characteristic frequency and its corresponding sideband.Then,according to time and frequency domain characteristics,fault location based on expert experience is proposed to get an accurate fault result.Finally,the proposed method is implemented in the equipment intelligent diagnosis system.By taking an equipment fault on site,for example,the effectiveness of the proposed method is illustrated in the system.

The Gas Resources Assessment Expert System of the Songliao Basin

The gas resources assessment expert system is one of the advanced methods for appraising oil and gas resources. The establishment of a knowledge base is the focal task in developing the expert system. This paper presents a summary of the mechanism and the major controlling factors in the formation of gas pools in the southeast uplift of the Songliao basin. Then an appropriate assessment model is established for trapping the gas resources and a knowledge base built in the expert system to realize the model. By using the expert system to appraise the gasbearing probability of 25 major traps of the Quantou and Denglouku Formations in the Shiwu-Dehui area, the authors have proved that the expert syster., is suitable for appraising traps in the Songliao basin and similar basins.

Integrated Expert Analytical System for Assessment of Oil-and-Gas Saturation of Strata

The present research deals with the problem of development of an integrated expert-analytical system for optimum selection of calculated oil-field-geophysical parameters of oil and gas deposits with the purpose of increasing the accuracy of assessment of the reserves of oil and gas deposits. The purpose of the system is to make current adequate decisions on determining of oil-and-gas saturation of strata and future identification of the most significant methods for that, with these methods forming the foundation of knowledge bases for oil-and-gas deposits of the Apsheron peninsula of Azerbaijan. The system architecture allows for expanding the system with its subsequent transformation into a cluster of expert-analytical systems. A logical model of the proposed system is presented. The paper contains a detailed description of the mechanism of operation of the system as a whole and of its individual blocks. Mathematical and formal-logical bases of the intelligent system are explained. The system is equipped with a tool for dynamic statistical analysis of decisions made by it, with representation of the results in real-time mode. The results of the system testing on specific oil-and-gas deposit of the Apsheron peninsula of Azerbaijan in 2013 are given.

Pre/Post Assessments Analysis in Training Electro-Technical Seafarers Experts

In maritime industry, personnel’s training is considered by shipping companies as a top priority matter on the list of factors affecting competitiveness in operating vessels. This paper presents the importance and the effects of training Electro-Technical Experts in the context of latest developments, particularly the advent of the “Electric Ship” and the “Communicative Ship” analyzing the feedback received from several relevant two-days seminars for “Ship Electrical and Electronic Systems for Electro-Technical Officers”, in North East European countries. The pre-test and post-test self assessment method that has been used for more efficient interaction between trainers and trainees is analyzed using t-statistics. The attendees have had diverse basic backgrounds, yet company experts Fleet Engineers on merchant or war ships. The training’s effectiveness and gain is discussed in this paper and further proposals for the Electrical and Electronic training are presented through the valuable feedback for improvement.

Expert consensus on irrigation and intracanal medication in root canal therapy

Chemical cleaning and disinfection are crucial steps for eliminating infection in root canal treatment. However, irrigant selection or irrigation procedures are far from clear. The vapor lock effect in the apical region has yet to be solved, impeding irrigation efficacy and resulting in residual infections and compromised treatment outcomes.

Interpretation of Chinese Expert Consensus on the Diagnosis and Management Strategy of Patients with Statin Intolerance: A guiding file for helping to lipid management for Chinese population

It is well-known that elevated low-density lipoprotein cholesterol(LDL-C)is a causal risk factor for atheroscler-otic cardiovascular disease(ASCVD),statins are cornerstone drugs for the cause-based treatment of ASCVD,which has created a new era for ASCVD therapy.However,statin intolerance is not clinically uncommon,which there are several issues with confu-sion and misunderstandings.Hence,a file named Chinese Expert Consensus on the Diagnosis and Management Strategy of Pa-tients With Statin Intolerance,like a navigator,has recently been published written by a team of experts from the Cardiovascular Metabolic Medicine Professional Committee,Expert Committee of the National Center for Cardiovascular Diseases aiming to en-hance the standardized clinical application of statins and improve the prevention and clinical outcome.In this article,author briefly summarized the key points of above consensus in order to helping to comprehending the content of the consensus sugges-tions.

Soil resilience assessment using soil profile descriptions and Analytic Hierarchy Process in Mediterranean mountains considering diverse fire occurrences

Wildfires are complex natural phenomena that exert significant impacts on landscapes,societies,and economies.Understanding the concept of resilience is crucial in mitigating its possible negative impacts,as it involves preparing for,responding to,and recovering from wildfires.This research aims to demonstrate the utility of in situ soil profile description in assessing land use resilience using an Analytic Hierarchy Process(AHP)through an expert panel survey.The study examines a catchment located in the Balearic Islands,considering two fire occurrences(once and twice),comparing abandoned agricultural terraces and natural hillslopes.The results demonstrated that the priority ranking of variables to assess soil profile resilience against wildfires,determined by a panel of 10 experts,identified horizon depth(25.1%),slope inclination(21.5%),and hydrological connectivity(16.6%)as the most crucial factors.Other variables,such as number and size of roots,structure of pedal soil material,size class structure,and rock fragments,also contributed to resilience but to a lesser extent,with scores ranging from 5.7%to 9.6%.Analyzing the priorities established by the experts using AHP,the results showed that the least resilient soil horizon was H1 of the control hillslope,especially under high and low connectivity processes,which aligned with the loss of superficial soil horizons after one and two wildfires.Hillslopes showed greater changes in resilience after occurring wildfires compared to terraces,with the most significant alterations occurring after the second wildfire event.This study addresses a significant knowledge gap in the field by highlighting the interconnectedness of wildfires,resilience,and land use,providing insights into land management strategies for wildfire-prone regions.

Fully Completed Spherical Fuzzy Approach-Based Z Numbers(PHIModel)for Enhanced Group Expert Consensus

This study aims to establish an expert consensus and enhance the efficacy of decision-making processes by integrating Spherical Fuzzy Sets(SFSs)and Z-Numbers(SFZs).A novel group expert consensus technique,the PHImodel,is developed to address the inherent limitations of both SFSs and the traditional Delphi technique,particularly in uncertain,complex scenarios.In such contexts,the accuracy of expert knowledge and the confidence in their judgments are pivotal considerations.This study provides the fundamental operational principles and aggregation operators associated with SFSs and Z-numbers,encompassing weighted geometric and arithmetic operators alongside fully developed operators tailored for SFZs numbers.Subsequently,a case study and comparative analysis are conducted to illustrate the practicality and effectiveness of the proposed operators and methodologies.Integrating the PHI model with SFZs numbers represents a significant advancement in decision-making frameworks reliant on expert input.Further,this combination serves as a comprehensive tool for decision-makers,enabling them to achieve heightened levels of consensus while concurrently assessing the reliability of expert contributions.The case study results demonstrate the PHI model’s utility in resolving complex decision-making scenarios,showcasing its ability to improve consensus-building processes and enhance decision outcomes.Additionally,the comparative analysis highlights the superiority of the integrated approach over traditional methodologies,underscoring its potential to revolutionize decision-making practices in uncertain environments.

Evaluation of a software positioning tool to support SMEs in adoption of big data analytics

Big data analytics has been widely adopted by large companies to achieve measurable benefits including increased profitability,customer demand forecasting,cheaper development of products,and improved stock control.Small and medium sized enterprises(SMEs)are the backbone of the global economy,comprising of 90%of businesses worldwide.However,only 10%SMEs have adopted big data analytics despite the competitive advantage they could achieve.Previous research has analysed the barriers to adoption and a strategic framework has been developed to help SMEs adopt big data analytics.The framework was converted into a scoring tool which has been applied to multiple case studies of SMEs in the UK.This paper documents the process of evaluating the framework based on the structured feedback from a focus group composed of experienced practitioners.The results of the evaluation are presented with a discussion on the results,and the paper concludes with recommendations to improve the scoring tool based on the proposed framework.The research demonstrates that this positioning tool is beneficial for SMEs to achieve competitive advantages by increasing the application of business intelligence and big data analytics.

企业技术难题与专家精准对接语言模型Expert-ChatGLM

传统方式下,企业引进技术领域的专家时,通常通过简历等信息筛选。但该方式存在同质化高、精准匹配难等问题。为此,建立一个能实现专家与企业需求精准对接的模型迫在眉睫。近年来,随着人工智能的发展,出现了很多大型语言模型,如OpenAI的ChatGPT、斯坦福的Alpaca和清华大学的ChatGLM-6B。虽然这些模型在指令和聊天方面取得了成绩,但对于专家与企业的精准对接尚有不足。因此,提出了专家与企业精准对接语言模型Expert-ChatGLM,该模型对研究采集构建的专家知识图谱以及专家对话数据集进行了微调,能够准确理解企业需求并提供精准的专家信息。该模型能提高寻找专家的效率和质量,具有很大的发展潜力。

UAV maneuvering decision-making algorithm based on deep reinforcement learning under the guidance of expert experience

Autonomous umanned aerial vehicle(UAV) manipulation is necessary for the defense department to execute tactical missions given by commanders in the future unmanned battlefield. A large amount of research has been devoted to improving the autonomous decision-making ability of UAV in an interactive environment, where finding the optimal maneuvering decisionmaking policy became one of the key issues for enabling the intelligence of UAV. In this paper, we propose a maneuvering decision-making algorithm for autonomous air-delivery based on deep reinforcement learning under the guidance of expert experience. Specifically, we refine the guidance towards area and guidance towards specific point tasks for the air-delivery process based on the traditional air-to-surface fire control methods.Moreover, we construct the UAV maneuvering decision-making model based on Markov decision processes(MDPs). Specifically, we present a reward shaping method for the guidance towards area and guidance towards specific point tasks using potential-based function and expert-guided advice. The proposed algorithm could accelerate the convergence of the maneuvering decision-making policy and increase the stability of the policy in terms of the output during the later stage of training process. The effectiveness of the proposed maneuvering decision-making policy is illustrated by the curves of training parameters and extensive experimental results for testing the trained policy.

German Automobile Expert:Cooperation Instead of Tariffs

“Europe has missed this development opportunity because we are short of a long-term vision.”MORE than 40 exhibitors from 15 major vehicle brands around the world,representing the latest cutting-edge technologies and models,gathered at the seventh China International Import Expo(CIIE),which was held in Shanghai from November 5 to 10.

British Law Expert:South China Sea Islands Are Chinese Territory

The History and Sovereignty of the South China Sea Islands clarifies the sovereignty over the South China Sea Islands with irrefutable facts.THE English edition of The History and Sovereignty of the South China Sea Islands was released by New Star Press under China International Communications Group at the 2024 Beijing International Book Fair on June 20.Prior to this,the Chinese version of the book,also published by New Star Press,had attracted wide attention from the international community.

Practice and Thinking of Agricultural Science and Technology Experts Serving the Grassroots to Promote Rural Revitalization

Provincial agricultural research institutes are local agricultural research institutions.They are familiar with local agricultural and ru-ral conditions,and have advantages in scientific and technological achievements,technical reserves and the construction of scientific and tech-nological talent support systems.In the process of promoting the implementation of the rural revitalization strategy,all the responsibilities and obligations of the agricultural research institute are to identify the focus of scientific and technological support and talent support in rural revital-ization,and break the bottleneck and constraints of rural revitalization.By sorting out the current situation of agricultural science and technolo-gy experts serving the grassroots in the problem of talent support for rural revitalization,this paper analyzed the existing problems and put for-ward countermeasures and recommendations.

Research and design of an expert diagnosis system for rail vehicle driven by data mechanism models

Purpose-The aim of this work is to research and design an expert diagnosis system for rail vehicle driven by data mechanism models.Design/methodology/approach-The expert diagnosis system utilizes statistical and deep learning methods to model the real-time status and historical data features of rail vehicle.Based on data mechanism models,it predicts the lifespan of key components,evaluates the health status of the vehicle and achieves intelligent monitoring and diagnosis of rail vehicle.Findings-The actual operation effect of this system shows that it has improved the intelligent level of the rail vehicle monitoring system,which helps operators to monitor the operation of vehicle online,predict potential risks and faults of vehicle and ensure the smooth and safe operation of vehicle.Originality/value-This system improves the efficiency of rail vehicle operation,scheduling and maintenance through intelligent monitoring and diagnosis of rail vehicle.

The Application of Knowledge Management(KM)by Small and Medium-Sized Enterprises(SME)in Manufacturing Industry

To accelerate the digital transformation of small and medium-sized manufacturing enterprises(SMEs),this study delves into the primary challenges encountered in adopting knowledge management(KM)within these organizations and identifies the essential methods for successful implementation.The objective is to provide practical recommendations for the effective adoption of KM.This research suggests that enterprises should promote knowledge management through three key approaches:enhancing employees’cognitive understanding,standardizing knowledge systems,and tailoring business scenarios to meet diverse needs.These findings offer valuable insights into the digital transformation of SMEs in the manufacturing sector,ultimately helping these businesses to remain competitive and innovative in a rapidly changing market.By addressing the specific needs and challenges faced by SMEs,this study aims to contribute to a more comprehensive understanding of how knowledge management can be leveraged to drive digital transformation and improve overall business performance.

基于Design-Expert的碱激发粉煤灰建筑外墙腻子配合比优化试验研究

为了拓展工业固体废弃物粉煤灰的回收利用途径,减少对环境造成的污染,增加其在筑材料中回收利用率。在建筑外墙腻子中加入碱性激发剂(Ca(OH)_(2)、Na_(2)SiO_(3))、粉煤灰,研究碱性激发剂的激发效果。同时通过Design-Expert设计试验,分析主要组分对腻子漆膜粘结强度、吸水量的影响。结果表明:加入碱性激发剂5%,粉煤灰32.5%时,吸水量减少14%,粘结强度增加43%。乳胶粉对吸水量、粘结强度的影响非常显著(P<0.0001),其次是粉煤灰的加入量。通过加入碱性激发剂、提高乳胶粉占比,粉煤灰掺量能达到32%~65%,原配比中水泥的掺量相对减少0%~16%。