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The Reform and Practice of Multicultural Cultivation Mode of Art Talents in Colleges and Universities Under the Strategy of “Three Highs and Four New”
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作者 Aihua Tian 《Journal of Contemporary Educational Research》 2024年第6期202-210,共9页
As an important link in the development of modern quality education,art education is one of the methods to guide students to have a diversified vision.Under the background of multiculturalism,we need to explore the co... As an important link in the development of modern quality education,art education is one of the methods to guide students to have a diversified vision.Under the background of multiculturalism,we need to explore the connotation and value of art education with the concept of“three highs and four new,”so that students can realize interdisciplinary and cross-cultural cognition through an immersive experience and practical operation in a wide range of multicultural situations,and to develop the knowledge of art education with the concept of“three highs and four new.”Based on the multicultural background,this paper focuses on the integration of multiculturalism into the reform practice of“student-centered”in colleges and universities,so as to cultivate art talents adapted to the multicultural background,in order to achieve the great mission of“three highs and four new”and better lead the innovative development of art education in colleges and universities. 展开更多
关键词 “Three highs and four new” Diversity Talent cultivation Reform PRACTICE
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A salt-induced tackifying polymer for enhancing oil recovery in highsalinity reservoirs:Synthesis,evaluation,and mechanism
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作者 Yining Wu Peihan Li +5 位作者 Bin Yan Xiaohan Li Yongping Huang Juncong Yuan Xiang Feng Caili Dai 《Green Energy & Environment》 SCIE EI CAS CSCD 2024年第11期1747-1758,共12页
Polymerflooding is an effective method widely applied for enhancing oil recovery(EOR)by reducing the mobility ratio between theinjected water and crude oil.However,traditional polymers encounter challenges in high sali... Polymerflooding is an effective method widely applied for enhancing oil recovery(EOR)by reducing the mobility ratio between theinjected water and crude oil.However,traditional polymers encounter challenges in high salinity reservoirs due to their salt sensitivity.Toovercome this challenge,we synthesized a zwitterion polymer(PAMNS)with salt-induced tackifying property through copolymerization ofacrylamide and a zwitterion monomer,methylacrylamide propyl-N,N-dimethylbutylsulfonate(NS).NS monomer is obtained from thereaction between 1,4-butanesultone and dimethylamino propyl methylacrylamide.In this study,the rheological properties,salt responsiveness,and EOR efficiency of PAMNS were evaluated.Results demonstrate that PAMNS exhibits desirable salt-induced tackifyingcharacteristics,with viscosity increasing up to 2.4 times as the NaCl concentration reaches a salinity of 30×10^(4)mg L^(-1).Furthermore,highvalence ions possess a much stronger effect on enhancing viscosity,manifested as Mg^(2+)>Ca^(2+)>Na^(+).Molecular dynamics simulations(MD)andfluid dynamics experiment results demonstrate that PAMNS molecules exhibit a more stretched state and enhanced intermolecularassociations in high-salinity environments.It is because of the salt-induced tackifying,PAMNS demonstrates superior performance inpolymerflooding experiments under salinity ranges from 5×10^(4)mg L^(-1)to 20×10^(4)mg L^(-1),leading to 10.38–19.83%higher EOR thantraditional polymers. 展开更多
关键词 High salinity reservoirs Salt-induced tackifying polymer Anti-polyelectrolyte behavior Enhanced oil recovery
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Response of global subtropical highs to the equatorial eastern Pacific SST anomaly
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作者 Gong Daoyi and Wang Shaowu 1. Department of Geophysics, Peking University, Beijing 100871, China (Received August 31, 1997 accepted March 30, 1998) 《Acta Oceanologica Sinica》 SCIE CAS CSCD 1999年第2期203-214,共12页
Based on the reanalysis data of global 500hPa geopotential height (NCEP NCAR CDAS-1) and tropical Pacific SSTs, the characteristics of global subtropical highs and their response to tropical eastern Pacific SST are i... Based on the reanalysis data of global 500hPa geopotential height (NCEP NCAR CDAS-1) and tropical Pacific SSTs, the characteristics of global subtropical highs and their response to tropical eastern Pacific SST are investigated. Results show that global subtropical highs respond to SST consistently. Subtropical high intensity correlates to the 3 months leading SST maximally. The relationship between SST and 500hPa height stands out in low latitudes. The time for 500hPa height reaching maximuxn correlation to SST is 2 months later in latitude of 10 degree and 9 months in latitude of 30 degree than equatorial zone. And the response of atmospheric circulation over extratropic performs as wave train, and the response is more significant in the condition of warmer SST. Persistence of SSTs and subtropical highs changes obviously from season to season. Minimum persistence of subtropical highs in September and October may relate to the low persistence of SSTs in August and September. 展开更多
关键词 Global subtropical highs equatorial eastern Pacific SST
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Money Flowing into Commodities Powers Cotton to Fresh Rally Highs
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《China Textile》 2009年第12期18-19,共2页
Money flowing into commodities-one analyst called it a "commodity pandemonium" - powered cotton futures to new rally highs last week in holiday-shortened trading.
关键词 DOWN Money Flowing into Commodities Powers Cotton to Fresh Rally highs
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Numerical Simulation of the Effect of the SST Anomalies in the Tropical Western Pacific on the Blocking Highs over the Northeastern Asia 被引量:7
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作者 陆日宇 黄荣辉 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 1996年第4期411-424,共14页
The effects of the sea surface temperature (SST) anomalies in the tropical western Pacific on the atmospheric circulation anomalies over East Asia are simulated by the IAP-GCM with an observed and idealized distributi... The effects of the sea surface temperature (SST) anomalies in the tropical western Pacific on the atmospheric circulation anomalies over East Asia are simulated by the IAP-GCM with an observed and idealized distributions of the SST anomalies in the tropical western Pacific,respectively.Firstly,the atmospheric circulation anomalies during July and August,1980 are simulated by three anomalous experiments including the global SST anomaly experiment,the tropical SST anomaly experiment and the extratropical SST anomaly experiment,using the observed SST anomalies in 1980.It is shown that the SST anomalies in the tropical ocean greatly influence the formation and maintenance of the blocking high over the northeastern Asia,and may play a more important role than the SST anomalies in the extratropical ocean in the influence on the atmospheric circulation anomalies.Secondly,the effects of the SST anomalies in the tropical western Pacific on the atmospheric circulation anomalies over East Asia are also simulated with an idealized distribution of the SST anomalies in the tropical western Pacific.The simulated results show that the negative anomalies of SST in the tropical western Pacific have a significant effect on the formation and maintenance of the blocking high over the northeastern Asia. 展开更多
关键词 Blocking high SST anomaly Atmospheric circulation anomaly
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Remote Impact of Blocking Highs on the Sudden Track Reversal of Tropical Cyclones 被引量:1
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作者 LUO Xia FEI Jianfang +2 位作者 HUANG Xiaogang CHENG Xiaoping YU Kun 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2015年第11期1517-1532,共16页
Previous work showed that some tropical cyclones (TCs) in the western Pacific Ocean undergo sudden track reversal, and the onset, maintenance and decay of blocking highs (BHs) coexisted with 19 of the studied TCs ... Previous work showed that some tropical cyclones (TCs) in the western Pacific Ocean undergo sudden track reversal, and the onset, maintenance and decay of blocking highs (BHs) coexisted with 19 of the studied TCs with sudden track reversal. In these cases, the phase relations between the BH, the continental high (CH), the subtropical high (SH) and the suddenly reversed TCs could be classified into types A, B, C and D. Types C and D were the focal point of this follow-up study, in which Typhoon Pabuk (2007) and Lupit (2009) were employed to conduct numerical simulations. The results showed that the reversed tracks of Pabuk (2007) and Lupit (2009) could have been affected by the BH, particularly in terms of the turning location and the trend of movement after turning. Specifically, the two main features for Pabuk (2007) in the BH perturbations were the deflection of its turning point and a distinct anticlockwise rotation. Lupit (2009) deviated to the southwest and finally made landfall in the Philippines, or experienced further eastward movement, in the perturbed BH. The impact mechanisms can be attributed to the change in the vorticity field transported from the BH, leading to an intensity variation of midlatitude systems. BHs may have a positive feedback effect on the strength of the westerly trough (TR), as indicated by a weakened and strengthened TR corresponding to negative and positive BH perturbations, respectively. 展开更多
关键词 blocking high tropical cyclone suddenly reversed track numerical simulation
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Elderly patients with non-cardiac admissions and elevated highsensitivity troponin:the prognostic value of renal function
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作者 Ioanna Samara Stavroula Tsiara +6 位作者 Michail I Papafaklis Konstantinos Pappas Georgios Kolios Nikolaos Vryzas Lampros K Michalis Eleni T Bairaktari Christos S Katsouras 《World Journal of Cardiology》 2021年第10期566-573,共8页
BACKGROUND High-sensitivity cardiac troponin(hs-cTn)levels are frequently elevated in elderly patients presenting to the emergency department for non-cardiac events.However,most studies on the role of elevated hs-cTn ... BACKGROUND High-sensitivity cardiac troponin(hs-cTn)levels are frequently elevated in elderly patients presenting to the emergency department for non-cardiac events.However,most studies on the role of elevated hs-cTn in elderly populations have investigated the prognostic value of hs-cTn in patients with a specific diagnosis or have assessed the relationship between hs-cTn and comorbidities.AIM To investigate the in-hospital prognosis of consecutive elderly patients admitted to the Internal Medicine Department with acute non-cardiac events and increased hs-cTnI levels.METHODS In this retrospective study,we selected patients who were aged≥65 years and admitted to the Internal Medicine Department of our hospital between January 2019 and December 2019 for non-cardiac reasons.Eligible patients were those who had hs-cTnI concentrations≥100 ng/L.We investigated the independent predictors of in-hospital mortality by multivariable logistic regression analysis.RESULTS One hundred and forty-six patients(59%female)were selected with an age range from 65 to 100(mean±SD:85.4±7.61)years.The median hs-cTnI value was 284.2 ng/L.For 72(49%)patients the diagnosis of hospitalization was an infectious disease.The overall in-hospital mortality was 32%(47 patients).Individuals who died did not have higher hs-cTnI levels compared with those who were discharged alive(median:314.8 vs 282.5 ng/L;P=0.565).There was no difference in mortality in patients with infectious vs non-infectious disease(29%vs 35%).Multivariable analysis showed that age(OR 1.062 per 1 year increase,95%CI:1.000-1.127;P=0.048)and creatinine levels(OR 2.065 per 1 mg/dL increase,95%CI:1.383-3.085;P<0.001)were the only independent predictors of death.Mortality was 49%in patients with eGFR<30 mL/min/1.73 m2.CONCLUSION Myocardial injury is a malignant condition in elderly patients admitted to the hospital for non-cardiac reasons.The presence of severe renal impairment is a marker of extremely high in-hospital mortality. 展开更多
关键词 Internal medicine High sensitivity troponin ELDERLY Non-cardiac admissions Renal function PROGNOSIS
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Research on the design of ballastless track in the subgrade section of highspeed railway in high earthquake-intensity area
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作者 Li Yao 《High-Speed Railway》 2023年第4期273-279,共7页
According to the characteristics of complex terrain and bad geological conditions in the southwest mountainous area of China, it is proposed that cast-in situ double-block ballastless track with layers and blocks stru... According to the characteristics of complex terrain and bad geological conditions in the southwest mountainous area of China, it is proposed that cast-in situ double-block ballastless track with layers and blocks structure should be adopted preferentially in the subgrade section of high-speed railway, which is conducive to the construction, prolongation of service life and maintenance of the ballastless track. Based on the finite element model, the dynamic performance, structural strength and stability of double-block ballastless track under high earthquake-intensity action are analyzed. The analysis shows that the relative displacement between the base slab of ballastless track and the subgrade may occur under 9 degree earthquake action. A new CRTS double-block ballastless track structure with a concave-convex structure between the base slab and the subgrade is proposed in the subgrade section, and its additional stress and relative displacement under earthquake are analyzed. The results show that the additional stress and relative displacement of the new ballastless track structure and the subgrade under 9-degree earthquake actions are small, which meet the high stability requirements of high-speed railway. 展开更多
关键词 High-speed railway High earthquake-intensity CRTS double-block ballastless track Track design Stability
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China’s carbon neutrality faces the challenges of“three highs and one short”,and requires“five carbon implementations”to achieve dual carbon goals
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作者 Kebin He 《iEnergy》 2023年第1期2-3,共2页
Dual carbon goals are closely related to high-quality green development.The government has required that dual car-bon goals be included in ecological civilization construction’s overall layout.Achieving carbon peak a... Dual carbon goals are closely related to high-quality green development.The government has required that dual car-bon goals be included in ecological civilization construction’s overall layout.Achieving carbon peak and carbon neutrality is a broad and profound systemic economic and social transformation.China is facing the“three highs and one short”challenges and requires the“five carbon implementations”to achieve dual carbon goals.The core of dual carbon goals is a new round of industrial competition,and the world is laying out dual carbon goals as the starting point and competing for a new round of technological high ground. 展开更多
关键词 NEUTRAL CARBON high
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Energetics of Boreal Wintertime Blocking Highs around the Ural Mountains 被引量:1
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作者 Ning SHI Yicheng WANG Suolangtajie 《Journal of Meteorological Research》 SCIE CSCD 2022年第1期154-174,共21页
Based on the daily Japanese 55-yr reanalysis data,this study analyzes the maintenance mechanism for 53 boreal winter blocking highs around the Ural Mountains(UBHs)during 1958-2018 based on the atmospheric energy budge... Based on the daily Japanese 55-yr reanalysis data,this study analyzes the maintenance mechanism for 53 boreal winter blocking highs around the Ural Mountains(UBHs)during 1958-2018 based on the atmospheric energy budget equations.After decomposing the circulation into background flow,low-frequency anomalies,and high-frequency eddies,it was found that the interaction between the background flow and low-frequency anomalies is conducive to the maintenance of the UBHs.Due to the southwestward gradient in the climatological mean air temperature over the Eurasian continent,it is easy for the air temperature anomalies as well as the wind velocity anomalies in the middle and lower troposphere induced by the UBHs to facilitate the positive conversion of baroclinic energy associated with the background flow into the UBHs.Likewise,the conversion of barotropic energy associated with the background flow is also evident in the upper troposphere,in which the climatological mean westerlies have evident southward gradient to the northwest of Lake Baikal and southwestward gradient over Barents Sea.Note that the conversion of baroclinic energy associated with the background flow is dominant throughout the lifecycle of UBHs,acting as the major contributor to the maintenance of the UBHs.Although transient eddies facilitate maintenance of the UBHs via positive conversion of barotropic energy in the middle and upper troposphere,they hinder the maintenance of UBHs via negative conversion of baroclinic energy in the lower troposphere.The diabatic heating anomalies tend to counteract the local air temperature anomalies in the middle and lower troposphere,which damps the available potential energy of UBHs and acts as a negative contributor to the UBHs. 展开更多
关键词 blocking highs around the Ural Mountains energy budget background flow transient eddies
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From waste to wealth:Coal tar residue derived carbon materials as low-cost anodes for potassium-ion batteries
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作者 Zhonghua Lu Jun Shen +5 位作者 Xin Zhang Lingcong Chao Liang Chen Ding Zhang Tao Wei Shoudong Xu 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS 2025年第2期464-475,共12页
Carbon materials are widely recognized as highly promising electrode materials for various energy storage system applications.Coal tar residues(CTR),as a type of carbon-rich solid waste with high value-added utilizati... Carbon materials are widely recognized as highly promising electrode materials for various energy storage system applications.Coal tar residues(CTR),as a type of carbon-rich solid waste with high value-added utilization,are crucially important for the development of a more sustainable world.In this study,we employed a straightforward direct carbonization method within the temperature range of 700-1000℃to convert the worthless solid waste CTR into economically valuable carbon materials as anodes for potassium-ion batteries(PIBs).The effect of carbonization temperature on the microstructure and the potassium ions storage properties of CTR-derived carbons(CTRCs)were systematically explored by structural and morphological characterization,alongside electrochemical performances assessment.Based on the co-regulation between the turbine layers,crystal structure,pore structure,functional groups,and electrical conductivity of CTR-derived carbon carbonized at 900℃(CTRC-900H),the electrode material with high reversible capacity of 265.6m Ah·g^(-1)at 50 m A·g^(-1),a desirable cycling stability with 93.8%capacity retention even after 100 cycles,and the remarkable rate performance for PIBs were obtained.Furthermore,cyclic voltammetry(CV)at different scan rates and galvanostatic intermittent titration technique(GITT)have been employed to explore the potassium ions storage mechanism and electrochemical kinetics of CTRCs.Results indicate that the electrode behavior is predominantly governed by surface-induced capacitive processes,particularly under high current densities,with the potassium storage mechanism characterized by an“adsorption-weak intercalation”mechanism.This work highlights the potential of CTR-based carbon as a promising electrode material category suitable for high-performance PIBs electrodes,while also provides valuable insights into the new avenues for the high value-added utilization of CTR. 展开更多
关键词 coal tar residue carbon materials ANODE potassium-ion batteries high value-added
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Sulfolane‑Based Flame‑Retardant Electrolyte for High‑Voltage Sodium‑Ion Batteries
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作者 Xuanlong He Jie Peng +15 位作者 Qingyun Lin Meng Li Weibin Chen Pei Liu Tao Huang Zhencheng Huang Yuying Liu Jiaojiao Deng Shenghua Ye Xuming Yang Xiangzhong Ren Xiaoping Ouyang Jianhong Liu Biwei Xiao Jiangtao Hu Qianling Zhang 《Nano-Micro Letters》 SCIE EI CAS 2025年第2期498-516,共19页
Sodium-ion batteries hold great promise as next-generation energy storage systems.However,the high instability of the electrode/electrolyte interphase during cycling has seriously hindered the development of SIBs.In p... Sodium-ion batteries hold great promise as next-generation energy storage systems.However,the high instability of the electrode/electrolyte interphase during cycling has seriously hindered the development of SIBs.In particular,an unstable cathode–electrolyte interphase(CEI)leads to successive electrolyte side reactions,transition metal leaching and rapid capacity decay,which tends to be exacerbated under high-voltage conditions.Therefore,constructing dense and stable CEIs are crucial for high-performance SIBs.This work reports localized high-concentration electrolyte by incorporating a highly oxidation-resistant sulfolane solvent with non-solvent diluent 1H,1H,5H-octafluoropentyl-1,1,2,2-tetrafluoroethyl ether,which exhibited excellent oxidative stability and was able to form thin,dense and homogeneous CEI.The excellent CEI enabled the O3-type layered oxide cathode NaNi_(1/3)Mn_(1/3)Fe_(1/3)O_(2)(NaNMF)to achieve stable cycling,with a capacity retention of 79.48%after 300 cycles at 1 C and 81.15%after 400 cycles at 2 C with a high charging voltage of 4.2 V.In addition,its nonflammable nature enhances the safety of SIBs.This work provides a viable pathway for the application of sulfolane-based electrolytes on SIBs and the design of next-generation high-voltage electrolytes. 展开更多
关键词 Sodium-ion batteries Sulfolane-based electrolyte High voltage Layered oxide cathode Flame retardant
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Ideal Bi‑Based Hybrid Anode Material for Ultrafast Charging of Sodium‑Ion Batteries at Extremely Low Temperatures
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作者 Jie Bai Jian Hui Jia +2 位作者 Yu Wang Chun Cheng Yang Qing Jiang 《Nano-Micro Letters》 SCIE EI CAS 2025年第3期152-167,共16页
Sodium-ion batteries have emerged as competitive substitutes for low-temperature applications due to severe capacity loss and safety concerns of lithium-ion batteries at−20°C or lower.However,the key capability o... Sodium-ion batteries have emerged as competitive substitutes for low-temperature applications due to severe capacity loss and safety concerns of lithium-ion batteries at−20°C or lower.However,the key capability of ultrafast charging at ultralow temperature for SIBs is rarely reported.Herein,a hybrid of Bi nanoparticles embedded in carbon nanorods is demonstrated as an ideal material to address this issue,which is synthesized via a high temperature shock method.Such a hybrid shows an unprecedented rate performance(237.9 mAh g^(−1) at 2 A g^(−1))at−60℃,outperforming all reported SIB anode materials.Coupled with a Na_(3)V_(2)(PO_(4))_(3)cathode,the energy density of the full cell can reach to 181.9 Wh kg^(−1) at−40°C.Based on this work,a novel strategy of high-rate activation is proposed to enhance performances of Bi-based materials in cryogenic conditions by creating new active sites for interfacial reaction under large current. 展开更多
关键词 Bi nanoparticles High temperature shock High-rate activation Ultrafast charging Low-temperature sodium-ion batteries
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The Mechanism of Heating Rate on the Secondary Recrystallization Evolution in Grain Oriented Silicon Steel
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作者 GAO Qian LI Jun +3 位作者 WANG Xianhui CAO Laifu GONG Jian LI Bo 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS 2025年第1期275-282,共8页
Grain-oriented silicon steels were prepared at different heating rates during high temperature annealing,in which the evolution of magnetic properties,grain orientations and precipitates were studied.To illustrate the... Grain-oriented silicon steels were prepared at different heating rates during high temperature annealing,in which the evolution of magnetic properties,grain orientations and precipitates were studied.To illustrate the Zener factor,the diameter and number density of precipitates of interrupted testing samples were statistically calculated.The effect of precipitate ripening on the Goss texture and magnetic property was investigated.Data indicated that the trend of Zener factor was similar under different heating rates,first increasing and then decreasing,and that the precipitate maturing was greatly inhibited as the heating rate increased.Secondary recrystallization was developed at the temperature of 1010℃when a heating rate of 5℃/h was used,resulting in Goss,Brass and{110}<227>oriented grains growing abnormally and a magnetic induction intensity of 1.90T.Furthermore,increasing the heating rate to 20℃/h would inhibit the development of undesirable oriented grains and obtain a sharp Goss texture.However,when the heating rate was extremely fast,such as 40℃/h,poor secondary recrystallization was developed with many island grains,corresponding to a decrease in magnetic induction intensity to 1.87 T.At a suitable heating rate of 20℃/h,the sharpest Goss texture and the highest magnetic induction of 1.94 T with an onset secondary recrystallization temperature of 1020℃were found among the experimental variables in this study.The heating rate affected the initial temperature of secondary recrystallization by controlling the maturation of precipitates,leading to the deviation and dispersion of Goss texture,thereby reducing the magnetic properties. 展开更多
关键词 high temperature annealing heating rate secondary recrystallization grain oriented silicon steel
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High Fe‑Loading Single‑Atom Catalyst Boosts ROS Production by Density Effect for Efficient Antibacterial Therapy
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作者 Si Chen Fang Huang +5 位作者 Lijie Mao Zhimin Zhang Han Lin Qixin Yan Xiangyu Lu Jianlin Shi 《Nano-Micro Letters》 SCIE EI CAS 2025年第2期187-203,共17页
The current single-atom catalysts(SACs)for medicine still suffer from the limited active site density.Here,we develop a synthetic method capable of increasing both the metal loading and mass-specific activity of SACs ... The current single-atom catalysts(SACs)for medicine still suffer from the limited active site density.Here,we develop a synthetic method capable of increasing both the metal loading and mass-specific activity of SACs by exchanging zinc with iron.The constructed iron SACs(h^(3)-FNC)with a high metal loading of 6.27 wt%and an optimized adjacent Fe distance of~4 A exhibit excellent oxidase-like catalytic performance without significant activity decay after being stored for six months and promising antibacterial effects.Attractively,a“density effect”has been found at a high-enough metal doping amount,at which individual active sites become close enough to interact with each other and alter the electronic structure,resulting in significantly boosted intrinsic activity of single-atomic iron sites in h^(3)-FNCs by 2.3 times compared to low-and medium-loading SACs.Consequently,the overall catalytic activity of h^(3)-FNC is highly improved,with mass activity and metal mass-specific activity that are,respectively,66 and 315 times higher than those of commercial Pt/C.In addition,h^(3)-FNCs demonstrate efficiently enhanced capability in catalyzing oxygen reduction into superoxide anion(O_(2)·^(−))and glutathione(GSH)depletion.Both in vitro and in vivo assays demonstrate the superior antibacterial efficacy of h^(3)-FNCs in promoting wound healing.This work presents an intriguing activity-enhancement effect in catalysts and exhibits impressive therapeutic efficacy in combating bacterial infections. 展开更多
关键词 Nanocatalytic medicine Single-atom catalysts Reactive oxygen species(ROS) High metal loading Oxidase catalysis
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Challenges and improvement strategies in the hospitalization of chronic multimorbid patients
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作者 Andres Fontalba-Navas Francisco Pozo Muñoz +4 位作者 Rogelio Garcia Cisneros Maria Jose Garcia Larrosa Maria del Mar Callejon Gil Ignacio Garcia Delgado Maria Belen Jimenez Martinez 《World Journal of Clinical Cases》 SCIE 2025年第3期35-41,共7页
BACKGROUND Addressing the growing challenge of hospitalizing chronic multimorbid patients,this study examines the strain these conditions impose on healthcare systems at a local level,focusing on a pilot program.Chron... BACKGROUND Addressing the growing challenge of hospitalizing chronic multimorbid patients,this study examines the strain these conditions impose on healthcare systems at a local level,focusing on a pilot program.Chronic diseases and complex patients require comprehensive management strategies to reduce healthcare burdens and improve patient outcomes.If proven effective,this pilot model has the potential to be replicated in other healthcare settings to enhance the management of chronic multimorbid patients.AIM To evaluate the effectiveness of the high complexity unit(HCU)in managing chronic multimorbid patients through a multidisciplinary care model and to compare it with standard hospital care.METHODS The study employed a descriptive longitudinal approach,analyzing data from the Basic Minimum Data Set(BMDS)to compare hospitalization variables among the HCU,the Internal Medicine Service,and other services at Antequera Hospital throughout 2022.The HCU,designed for patients with complex chronic conditions,integrates a patient-centered model emphasizing multidisciplinary care and continuity post-discharge.RESULTS The study employed a descriptive longitudinal approach,analyzing data from the BMDS to compare hospitalization variables among the HCU,the Internal Medicine Service,and other services at Antequera Hospital throughout 2022.The HCU,designed for patients with complex chronic conditions,integrates a patient-centered model emphasizing multidisciplinary care and continuity post-discharge.CONCLUSION This study demonstrates the effectiveness of the HCU in managing patients with complex chronic diseases through a multidisciplinary approach.The coordinated care provided by the HCU results in improved patient outcomes,reduced unnecessary hospitalizations,and better management of patient complexity.The superiority of the HCU compared to standard care is evident in key outcomes such as fewer readmissions and higher patient satisfaction,reinforcing its value as a model of care to be replicated. 展开更多
关键词 High complexity unit Chronic multimorbidity Patient-centered care Integrated care Healthcare management
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High mobility group box 1 in the central nervous system:regeneration hidden beneath inflammation
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作者 Hanki Kim Bum Jun Kim +4 位作者 Seungyon Koh Hyo Jin Cho Xuelian Jin Byung Gon Kim Jun Young Choi 《Neural Regeneration Research》 SCIE CAS 2025年第1期107-115,共9页
High-mobility group box 1 was first discovered in the calf thymus as a DNA-binding nuclear protein and has been widely studied in diverse fields,including neurology and neuroscience.High-mobility group box 1 in the ex... High-mobility group box 1 was first discovered in the calf thymus as a DNA-binding nuclear protein and has been widely studied in diverse fields,including neurology and neuroscience.High-mobility group box 1 in the extracellular space functions as a pro-inflammatory damage-associated molecular pattern,which has been proven to play an important role in a wide variety of central nervous system disorders such as ischemic stroke,Alzheimer’s disease,frontotemporal dementia,Parkinson’s disease,multiple sclerosis,epilepsy,and traumatic brain injury.Several drugs that inhibit high-mobility group box 1 as a damage-associated molecular pattern,such as glycyrrhizin,ethyl pyruvate,and neutralizing anti-high-mobility group box 1 antibodies,are commonly used to target high-mobility group box 1 activity in central nervous system disorders.Although it is commonly known for its detrimental inflammatory effect,high-mobility group box 1 has also been shown to have beneficial pro-regenerative roles in central nervous system disorders.In this narrative review,we provide a brief summary of the history of high-mobility group box 1 research and its characterization as a damage-associated molecular pattern,its downstream receptors,and intracellular signaling pathways,how high-mobility group box 1 exerts the repair-favoring roles in general and in the central nervous system,and clues on how to differentiate the pro-regenerative from the pro-inflammatory role.Research targeting high-mobility group box 1 in the central nervous system may benefit from differentiating between the two functions rather than overall suppression of high-mobility group box 1. 展开更多
关键词 central nervous system damage-associated molecular pattern ethyl pyruvate glycyrhizzin high mobility group box 1 INFLAMMATION neural stem cells NEURODEVELOPMENT oligodendrocyte progenitor cells redox status REGENERATION
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A high entropy stabilized perovskite oxide La_(0.2)Pr_(0.2)Sm_(0.2)Gd_(0.2)Sr_(0.2)Co_(0.8)Fe_(0.2)O_(3−δ)as a promising air electrode for reversible solid oxide cells
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作者 LI Ruoyu LI Xiaoyu +2 位作者 ZHANG Jinke GAO Yuan LING Yihan 《燃料化学学报(中英文)》 北大核心 2025年第2期282-290,共9页
Reversible solid oxide cell(RSOC)is a new energy conversion device with significant applications,especially for power grid peaking shaving.However,the reversible conversion process of power generation/energy storage p... Reversible solid oxide cell(RSOC)is a new energy conversion device with significant applications,especially for power grid peaking shaving.However,the reversible conversion process of power generation/energy storage poses challenges for the performance and stability of air electrodes.In this work,a novel high-entropy perovskite oxide La_(0.2)Pr_(0.2)Gd_(0.2)Sm_(0.2)Sr_(0.2)Co_(0.8)Fe_(0.2)O_(3−δ)(HE-LSCF)is proposed and investigated as an air electrode in RSOC.The electrochemical behavior of HE-LSCF was studied as an air electrode in both fuel cell and electrolysis modes.The polarization impedance(Rp)of the HE-LSCF electrode is only 0.25Ω·cm^(2) at 800℃ in an air atmosphere.Notably,at an electrolytic voltage of 2 V and a temperature of 800℃,the current density reaches up to 1.68 A/cm^(2).The HE-LSCF air electrode exhibited excellent reversibility and stability,and its electrochemical performance remains stable after 100 h of reversible operation.With these advantages,HE-LSCF is shown to be an excellent air electrode for RSOC. 展开更多
关键词 reversible solid oxide cell high entropy stabilized perovskite air electrode electrochemical performance
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De novo-design of highly exposed Co−N−C single-atom catalyst for oxygen reduction reaction
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作者 ZHOU Dan ZHU Hongyue +1 位作者 ZHAO Yang LIU Yiming 《燃料化学学报(中英文)》 北大核心 2025年第1期128-137,共10页
The nitrogen-coordinated metal single-atom catalysts(M−N−C SACs)with an ultra-high metal loading synthetized by direct high-temperature pyrolysis have been widely reported.However,most of metal single atoms in these c... The nitrogen-coordinated metal single-atom catalysts(M−N−C SACs)with an ultra-high metal loading synthetized by direct high-temperature pyrolysis have been widely reported.However,most of metal single atoms in these catalysts were buried in the carbon matrix,resulting in a low metal utilization and inaccessibility for adsorption of reactants during the catalytic process.Herein,we reported a facile synthesis based on the hard-soft acid-base(HSAB)theory to fabricate Co single-atom catalysts with highly exposed metal atoms ligated to the external pyridinic-N sites of a nitrogen-doped carbon support.Benefiting from the highly accessible Co active sites,the prepared Co−N−C SAC exhibited a superior oxygen reduction reactivity comparable to that of the commercial Pt/C catalyst,showing a high turnover frequency(TOF)of 0.93 e^(−)·s^(-1)·site^(-1)at 0.85 V vs.RHE,far exceeding those of some representative SACs with a ultra-high metal content.This work provides a rational strategy to design and prepare M−N−C single-atom catalysts featured with high site-accessibility and site-density. 展开更多
关键词 hard-soft acid-base Co−N−C single-atom catalyst highly accessible active sites oxygen reduction reaction
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Taming of trinitromethyl-oxadiazole to access high density and high oxygen balance via a dual modulation strategy
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作者 Jinya Zhang Teng Fei +4 位作者 Jingwei Meng Jinxiong Cai Lei Zhang Siping Pang Chunlin He 《Defence Technology(防务技术)》 2025年第1期142-149,共8页
Energetic compounds bearing the trinitromethyl group are garnering broad attraction as potential candidates for a new generation of high energy dense oxidizers.In this work,an effective dual modulation strategy involv... Energetic compounds bearing the trinitromethyl group are garnering broad attraction as potential candidates for a new generation of high energy dense oxidizers.In this work,an effective dual modulation strategy involving both molecular isomerization and crystal morphology control was employed to design and optimize trinitromethyl-oxadiazole with improved comprehensive performance.Utilizing this dual strategy,3,5-bis(trinitromethyl)-1,2,4-oxadiazole(3)was synthesized,resulting in the formation of two distinct crystal morphologies(needle and sheet)corresponding to two crystal forms(3-a and3-b).Encouragingly,while maintaining ultra-high oxygen balance(21.73%),3 achieves impressive densities(1.97-1.98 g/cm^(3)).To our knowledge,the density of 1.98 g/cm^(3)for 3-a sets a new record among that of nitrogen-rich monocyclic compounds.Notably,practical crystal morphology prediction was creatively introduced to guide the experimental crystallization conditions of 3,increasing the impact sensitivity and friction sensitivity from 1 J to 80 N(3-a)to 10 J and 240 N(3-b),respectively.Additionally,the crystal structural analyses and theoretical calculations were conducted to elucidate the reasons of differences between 3-a and 3-b in density and stability.This work provides an efficient strategy to enhance performance of trinitromethyl derivatives,broadening the path and expanding the toolbox for energetic materials. 展开更多
关键词 Energetic materials High oxygen balance High density Dual modulation Trinitromethyl group
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