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Research on Leading Edge Erosion and Aerodynamic Characteristics of Wind Turbine Blade Airfoil
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作者 Xin Guan Yuqi Xie +2 位作者 Shuaijie Wang Mingyang Li Shiwei Wu 《Fluid Dynamics & Materials Processing》 EI 2024年第9期2045-2058,共14页
The effects of the erosion present on the leading edge of a wind turbine airfoil(DU 96-W-180)on its aerodynamic performances have been investigated numerically in the framework of a SST k–ωturbulence model based on ... The effects of the erosion present on the leading edge of a wind turbine airfoil(DU 96-W-180)on its aerodynamic performances have been investigated numerically in the framework of a SST k–ωturbulence model based on the Reynolds Averaged Navier-Stokes equations(RANS).The results indicate that when sand-induced holes and small pits are involved as leading edge wear features,they have a minimal influence on the lift and drag coefficients of the airfoil.However,if delamination occurs in the same airfoil region,it significantly impacts the lift and resistance characteristics of the airfoil.Specifically,as the angle of attack grows,there is a significant decrease in the lift coefficient accompanied by a sharp increase in the drag coefficient.As wear intensifies,these effects gradually increase.Moreover,the leading edge wear can exacerbate flow separation near the trailing edge suction surface of the airfoil and cause forward displacement of the separation point. 展开更多
关键词 Wind energy wind turbine EROSION AIRFOIL leading edge erosion characteristics aerodynamic performance numerical simulation
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Leading Pattern of Spring Drought Variability over East Asia and Associated Drivers
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作者 赵庆红 杨崧 +1 位作者 田红瑛 邓开强 《Journal of Tropical Meteorology》 SCIE 2024年第1期1-10,共10页
Drought events have become more frequent and intense over East Asia in recent decades,leading to huge socioeconomic impacts.Although the droughts have been studied extensively by cases or for individual regions,their ... Drought events have become more frequent and intense over East Asia in recent decades,leading to huge socioeconomic impacts.Although the droughts have been studied extensively by cases or for individual regions,their leading variability and associated causes remain unclear.Based on the Standardized Precipitation Evapotranspiration Index(SPEI)and ERA5 reanalysis product from 1979 to 2020,this study evealuates the severity of spring droughts in East Asia and investigates their variations and associated drivers.The results indicate that North China and Mongolia have experienced remarkable trends toward dryness during spring in recent decades,while southwestern China has witnessed an opposite trend toward wetness.The first Empirical Orthogonal Function mode of SPEI variability reveals a similar seesawing pattern,with more severe dryness in northwestern China,Mongolia,North China,South Korea,and Japan but increased wetness in Southwestern China and southeast Asia.Further investigation reveals that the anomalously dry(wet)surface in North(Southwestern)China is significantly associated with anomalously high(low)temperature,less(more)precipitation,and reduced(increased)soil moisture during the previous winter and early spring,regulated by an anomalous anticyclone(cyclone)and thus reduced(increased)water vapor convergence.The spring dry-wet pattern in East Asia is also linked to cold sea surface temperature anomalies in the central-eastern Pacific.The findings of this study have important implications for improving the prediction of spring drought events in East Asia. 展开更多
关键词 DROUGHT leading pattern East Asia spring DRIVERS
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Exploring the Path of Party Building Leading League Construction in Colleges and Universities under the Pattern of Great Ideological and Political Education
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作者 Yi SHENG Tao LI 《Asian Agricultural Research》 2024年第5期42-46,共5页
In accordance with the pattern of"great ideology and politics",the Party and youth League organizations assume the role of vanguard in the organization of colleges and universities.Simultaneously,they serve ... In accordance with the pattern of"great ideology and politics",the Party and youth League organizations assume the role of vanguard in the organization of colleges and universities.Simultaneously,they serve as a pivotal force in ideological and political education.In order to construct a comprehensive ideological and political framework encompassing the entire educational process,it is of paramount importance to identify an efficacious methodology for Party building leading League construction.This paper employs a comprehensive analysis to elucidate the pivotal role of Party building leading League construction in facilitating ideological and political education.It also illuminates the practical challenges encountered in the implementation of Party building leading League construction initiatives within colleges and universities.The article proposes a specific path for Party building leading League construction in colleges and universities based on three key aspects:cohesion of the consensus of Party building leading League building,establishment of the institutional system of Party building leading League construction,and creation of the model brand of Party building leading League construction.The aim is to promote in-depth development of Party building in colleges and universities and enhance the quality and effect of ideological and political education. 展开更多
关键词 Great ideological and political education pattern Party building in universities and colleges Party building leading League construction
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Transition from the Southern Mode of the Mei-yu Front Cloud System to Other Leading Modes 被引量:1
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作者 QIN Danyu LI Bo HUANG Yong 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2014年第4期948-961,共14页
Based on normalized six-hourly black body temperature (TBB) data of three geostationary meteorological satellites,the leading modes of the mei-yu cloud system between 1998 and 2008 were extracted by the Empirical Or... Based on normalized six-hourly black body temperature (TBB) data of three geostationary meteorological satellites,the leading modes of the mei-yu cloud system between 1998 and 2008 were extracted by the Empirical Orthogonal Function (EOF) method,and the transition processes from the first typical leading mode to other leading modes were discussed and compared.The analysis shows that,when the southern mode (EOF1) transforms to the northeastern mode (EOF3),in the mid-troposphere,a low trough develops and moves southeastward over central and eastern China.The circulation pattern is characterized by two highs and one low in the lower troposphere.A belt of low pressure is sandwiched between the weak high over central and western China and the strong western North Pacific subtropical high (WNPSH).Cold air moves southward along the northerly flow behind the low,and meets the warm and moist air between the WNPSH and the forepart of the low trough,which leads to continuous convection.At the same time,the central extent of the WNPSH increases while its ridge extends westward.In addition,transitions from the southern mode to the dual centers mode and the tropical-low-influenced mode were found to be atypical,and so no common points could be concluded.Furthermore,the choice of threshold value can affect the number of samples discussed. 展开更多
关键词 black body temperature mei-yu front cloud system leading modes mode transition
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Dynamical Predictability of Leading Interannual Variability Modes of the Asian-Australian Monsoon in Climate Models 被引量:1
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作者 Lin WANG Hong-Li REN +2 位作者 Fang ZHOU Nick DUNSTONE Xiangde XU 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2023年第11期1998-2012,I0002,I0003,共17页
The dynamical prediction of the Asian-Australian monsoon(AAM)has been an important and long-standing issue in climate science.In this study,the predictability of the first two leading modes of the AAM is studied using... The dynamical prediction of the Asian-Australian monsoon(AAM)has been an important and long-standing issue in climate science.In this study,the predictability of the first two leading modes of the AAM is studied using retrospective prediction datasets from the seasonal forecasting models in four operational centers worldwide.Results show that the model predictability of the leading AAM modes is sensitive to how they are defined in different seasonal sequences,especially for the second mode.The first AAM mode,from various seasonal sequences,coincides with the El Niño phase transition in the eastern-central Pacific.The second mode,initialized from boreal summer and autumn,leads El Niño by about one year but can exist during the decay phase of El Niño when initialized from boreal winter and spring.Our findings hint that ENSO,as an early signal,is conducive to better performance of model predictions in capturing the spatiotemporal variations of the leading AAM modes.Still,the persistence barrier of ENSO in spring leads to poor forecasting skills of spatial features.The multimodel ensemble(MME)mean shows some advantage in capturing the spatiotemporal variations of the AAM modes but does not provide a significant improvement in predicting its temporal features compared to the best individual models in predicting its temporal features.The BCC_CSM1.1M shows promising skill in predicting the two AAM indices associated with two leading AAM modes.The predictability demonstrated in this study is potentially useful for AAM prediction in operational and climate services. 展开更多
关键词 Asian-Australian monsoon(AAM) leading interannual variability modes El Niño seasonal forecasting models multimodel ensemble(MME)
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The Evaluation Indicator System for the Audit of Township Leading Cadres' Economic Responsibility: Based on the Survey of One County in Chongqing
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作者 Yanfen LUO Chaozhou LU 《Asian Agricultural Research》 2014年第10期48-52,共5页
Economic responsibility audit evaluation of township cadres is important and difficult. According to the evaluation content and principles,the paper constructs the evaluation indicator of five subsystems: " econo... Economic responsibility audit evaluation of township cadres is important and difficult. According to the evaluation content and principles,the paper constructs the evaluation indicator of five subsystems: " economic management", " economic decision-making", " implementation of economic policy", " economic development",and " honest and upright administration". Through the field survey of some county in Chongqing,evaluation indicator is screened. According to the expert questionnaire,it uses the Hierarchy Analysis Process method to construct the judgment matrix and calculate the indicator weight and thereby build evaluation indicator system. It focuses on traditional indicators and evaluation indicator of sustainable development to construct a new,more complete evaluation indicator system. 展开更多
关键词 Township leading CADRES Economic RESPONSIBILITY au
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Numerical Study on the Duct Noise Control of Single-Stage Axial Flow Fan with Wave Leading Edge Stator Blade Configurations 被引量:1
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作者 Jianxin Lian Hang Tong +2 位作者 Liangji Zhang Weiyang Qiao Weijie Chen 《Journal of Applied Mathematics and Physics》 2023年第8期2503-2514,共12页
This study focuses on a single-stage axial flow fan, investigating the effect of three kinds of wave leading edge stator blades on its noise reduction. The DDES method and the duct acoustic analogy theory based on the... This study focuses on a single-stage axial flow fan, investigating the effect of three kinds of wave leading edge stator blades on its noise reduction. The DDES method and the duct acoustic analogy theory based on the penetrable data surface were used for noise prediction. The results showed that the three kinds of wave leading edge blades were effective in reducing the rotor-stator interaction tonal noise and also have a certain inhibitory effect on broadband noise. The A10W15 stator blade can effectively reduce broadband noise in the frequency range of 2200 - 4200 Hz. When the amplitude is increased to 20, the noise reduction effect is further enhanced. However, when the amplitude is increased to 30, the broadband noise reduction effect is no longer significant. Further research shows that the wave leading edge stator blades can significantly change the pressure fluctuation distribution on the leading edge and suction surface, which control the modal energy distribution. Finally, this paper analyzed multiple factors affecting the broadband noise reduction, such as the noise source cut-off and cut-on effect and correlation. The purpose of this paper is to explore the laws of the influence of wave leading edge blades on the duct noise of real fan, and to reveal its noise control mechanism. . 展开更多
关键词 FAN Wave leading Edge Blade Duct Noise Broadband Noise Noise Source Analysis
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ZTE Inks Strategic Agreements with Two Leading European Telecom System Integrators
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《ZTE Communications》 2008年第1期61-61,共1页
ZTE Corporation has signed strategic telecommunications software agreement with two leading providers in Europe and Latin America to optimize its offerings for target customers in
关键词 ZTE Inks Strategic Agreements with Two leading European Telecom system Integrators
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Research on the Evolution of Media Practices of Leading Cadres’ New Media and the Communication Characteristics
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作者 Hebin Zhang Muhammad Zaffwan Idris 《Social Networking》 2023年第3期57-66,共13页
Purpose/Significance: This study aims to define the concept of leading cadres new media usage in China specifically, and to describe and analyze the forms and typical cases and characteristics of leading cadres new me... Purpose/Significance: This study aims to define the concept of leading cadres new media usage in China specifically, and to describe and analyze the forms and typical cases and characteristics of leading cadres new media in different stages. Method/Process: Based on the themes and contents of a few media accounts of leading cadres at different ranks, we summarizes leading cadres new media usage in a systematic perspective and content analysize method. Result/Conclusion: The study defines the concept of Leading Cadres’ new media from the perspective of media practice, determine its position as a media communication platform in the government affairs new media communication system and its relationship with the other elements, and then systematically review the evolution of its media practice from personal website, blog, microblog and microblog to WeChat, live show. On this basis, with the Harold Lasswell communication model, this article summarizes leading cadres new media communication characteristics from five aspects: content producer, content, channel, audience, and effect. Future studies may also enhance the empirical research from the effect perspective. 展开更多
关键词 leading Cadres’ New Media Evolution of Media Practices Communication Characteristics
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Piezoelectric resonant ice protection systems–Part1/2:Prediction of power requirement for de-icing a NACA 0024 leading edge 被引量:1
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作者 Valerian PALANQUE Jason POTHIN +1 位作者 Vale′rie POMMIER-BUDINGER Marc BUDINGER 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2024年第3期92-103,共12页
This paper proposes a numerical method to analyze the ice protection capability and predict the power requirements of a piezoelectric resonant de-icing system.The method is based on a coupled electro-mechanical finite... This paper proposes a numerical method to analyze the ice protection capability and predict the power requirements of a piezoelectric resonant de-icing system.The method is based on a coupled electro-mechanical finite element analysis which enables the fast computation of the modes of resonance of interest to de-ice curved surfaces and the estimation of the input voltage and current required for a given configuration(defined by its mode,actuator location,ice deposit,etc.).Eventually,the electric power to be supplied can be also assessed.The method is applied to a NACA 0024 leading edge equipped with piezoelectric actuators.First,two extension modes are analyzed and compared with respect to their efficiency and power requirements.Then,tests are carried out in an icing tunnel to verify the effectiveness of the piezoelectric ice protection system and the predictions of the maximal required power.The system allows de-icing the leading edge in less than 2 s for a glaze ice deposit. 展开更多
关键词 Ice protection system PIEZOELECTRIC Resonance mode Ice fracture leading edge de-icing
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Development of Management Systems for Electric Vehicle Battery Series 被引量:2
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作者 张承宁 孙逢春 +1 位作者 赵宏杰 孙立清 《Journal of Beijing Institute of Technology》 EI CAS 2000年第1期94-100,共7页
A kind of management system for electric vehicle (EV) battery series was developed. The system can predict residual capacity for EV battery series and mileages. The system can determine if it is necessary for the batt... A kind of management system for electric vehicle (EV) battery series was developed. The system can predict residual capacity for EV battery series and mileages. The system can determine if it is necessary for the battery series to be charged. The system can determine which battery is necessary to be updated for the reason of damage or aging. The system can display the total voltage of battery series, extreme voltage and temperature of every battery in the series. The system can display the accumulative discharge for every battery in the series. The system can alarm when both total or extreme voltage is at low level, or temperature of a battery in the series is at high level. The system provided with a microprocessor as key part can collect and record signal of charging and discharging current, total voltage, extreme voltage and temperature for every battery. The mathematical model of residual capacity for EV lead acid batteries was discussed in details. The system operates well in the laboratory and meets the requirement. 展开更多
关键词 electric vehicle (EV) residual capacity trouble diagnosis lead acid batteries
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Vapor pressure measurement of lead and lead chlorides in FeO_T-CaO-SiO_2-Al_2O_3 system 被引量:1
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作者 张延玲 Eiki KASAI 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2015年第8期2772-2780,共9页
Vapor pressure of lead and lead chlorides from FeOT?CaO?SiO2?Al2O3 slag system was measured by using Knudsen effusion method. The results suggest that the vapor pressures of lead and lead chlorides increase with in... Vapor pressure of lead and lead chlorides from FeOT?CaO?SiO2?Al2O3 slag system was measured by using Knudsen effusion method. The results suggest that the vapor pressures of lead and lead chlorides increase with increasing temperature. For the slag systems without chlorine, the logarithm of vapor pressure (lnp) shows highly linear dependency on the reciprocal of temperature (1/T), and higher vapor pressure is observed in the condition where more metallic lead vapor is formed. In this case, the vapor pressure of lead increases with increasing slag basicity (w(CaO)/w(SiO2)), increasing FeO content andw(Fe2+)/w(Fe3+) ratio. For the case of slag system with chlorine addition, the total pressures of PbCl2 and PbCl increase with decreasing basicity and FeO content of slag. 展开更多
关键词 金属Pb vapor pressure Knudsen effusion method metallic Pb lead chlorides smelting process
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The Study on Innovation Model Characteristics and Function Enhancement of “Leading Grain Enterprises+Farmers” in New Circumstances——an Investigation and Analysis on Major Grainproducing Areas in Hubei Province 被引量:1
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作者 曾靖 《Agricultural Science & Technology》 CAS 2016年第12期2896-2900,共5页
ln the context of comprehensively deepening the reform, and integration of three The first, second and third industry sectors in rural areas, the research took major grain-producing areas in Hubei as an example, analy... ln the context of comprehensively deepening the reform, and integration of three The first, second and third industry sectors in rural areas, the research took major grain-producing areas in Hubei as an example, analyzed dominant grain in-dustrialization models “leading grain enterprises+farmers”, and revealed its character-istics, advantages, and approaches for function reinforcement. The research is so meaningful, practical y or in future. 展开更多
关键词 Major grain-producing area leading grain enterprises FARMERS Linkage organization lnnovation model
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Interphase migration and enrichment of lead and zinc during copper slag depletion
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作者 Jun HAO Zhi-he DOU +2 位作者 Xing-yuan WAN Ting-an ZHANG Kun WANG 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2024年第9期3029-3041,共13页
An interphase migration and enrichment model of lead and zinc during molten copper slag depletion was established.The occurrence of various components in copper slag was predicted using sulfur-oxygen potential calcula... An interphase migration and enrichment model of lead and zinc during molten copper slag depletion was established.The occurrence of various components in copper slag was predicted using sulfur-oxygen potential calculations and confirmed through high-temperature experiments.The recovery rate of copper can reach 90.13%under the optimal conditions of 1200°C,an iron to silicon mass ratio of 1.0,3 wt.%ferrous sulfide,and a duration of 45 min.Lead(54.07 wt.%)and zinc(17.42 wt.%)are found in the flue dust as lead sulfate,lead sulfide,and zinc oxide,while copper matte contains lead(14.44 wt.%)and zinc sulfide(1.29 wt.%).The remaining lead and zinc are encapsulated as oxides within the fayalite phase. 展开更多
关键词 depletion LEAD copper slag STIRRING ZINC
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A short overview of the lead iodide residue impact and regulation strategies in perovskite solar cells
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作者 Eng Liang Lim Zhanhua Wei 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第3期504-510,I0012,共8页
Lead iodide(PbI2) is a vital raw material for preparing perovskite solar cells(PSCs),and it not only takes part in forming the light absorption layer but also remains in the grain boundary as a passivator.In other wor... Lead iodide(PbI2) is a vital raw material for preparing perovskite solar cells(PSCs),and it not only takes part in forming the light absorption layer but also remains in the grain boundary as a passivator.In other words,the PbI2 content in the precursor and as formed film will affect the efficiency and stability of the PSCs.With moderate residual PbI2,it passivates the bulk/surface defects of perovskite,reduces the interfacial recombination,promotes the perovskite stability,minimizes the device hysteresis,and so on.Deficient PbI2 residue will reduce the interfacial passivation effect and device performance.In addition to facilitating the non-radiative recombination,over PbI2 residue can also lead to electronic insulation in the grain boundary and deteriorate the device performance.However,the impact and regulation of PbI2 residue on the device performance and stability is still not fully understood.Herein,a comprehensive and detailed review is presented by discussing the PbI2 residue impact and its regulation strategies(i.e., elimination,facilitation and conversion of the residue PbI2) to manipulate the PbI2 content,distribution and forms.Finally,we also show future outlooks in this field,with an aim to help further the progression of high-efficiency and stable PSCs. 展开更多
关键词 Lead iodide RESIDUE REGULATION Perovskite solar cells Efficiency Stability
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In-situ defect passivation assisted three-step printing of efficient and stable formamidine-lead bromide solar cells
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作者 Hang Yang Tao Zhou +6 位作者 Haoyu Cai Wenjian Shen Hao Chen Yongjun Liu Juan Zhao Yi-Bing Cheng Jie Zhong 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第9期396-405,共10页
Perovskite solar cells(PSCs)emerge as the most promising photovoltaics(PV)for their high performance and potential convenient cost-effective production routes comparing to the sophomore PV technologies.The printed PSC... Perovskite solar cells(PSCs)emerge as the most promising photovoltaics(PV)for their high performance and potential convenient cost-effective production routes comparing to the sophomore PV technologies.The printed PSCs with simplified device architecture and fabrication procedures could further enhance the competitive strength of PSC technology.In this work,we present an in-situ defect passivation(ISDP)assisted full-printing of high performance formamidine-lead bromide(FAPbBr_(3))PSCs.Only three rapid printing steps are involved for electron transporting layer(ETL),perovskite and carbon to form a complete solar cell on the low-cost fluorine-doped tin oxide(FTO)substrate.Long-chain polymer monomethyl ether polyethylene glycol is particularly utilized as the ISDP passivator,leading to conformal coating on the rough FTO and defect passivation for both ETL and perovskite during printing.A high efficiency of 10.85%(certified 10.14%)and a high V_(oc)up to 1.57 V are achieved for the printed device.The unencapsulated PSCs maintain above 90%of the initial efficiency after continuously heating at 85℃for 1000 h and over 80%of the efficiency after the maximum power point tracking for 3500 h.The fully printed semitransparent PSCs with carbon grids(CGs)show average visible light transmittance over 33%and an efficiency of 8.81%. 展开更多
关键词 Formamidinium lead bromide Fully printed Lowcosts Carbon electrode SEMITRANSPARENT
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Cooperative composites anchored with single atom Pb and carbon confined PbO nanoparticles for superior lead-carbon batteries
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作者 Puqiang He Yi Yang +4 位作者 Hui Huang Jing Huang Hongbiao Wang Yapeng He Zhongcheng Guo 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第10期486-497,I0010,共13页
The mitigation of sulphation and parasitic hydrogen evolution is considered as prominent research emphasis for the development of lead-carbon batteries(LCBs)in large-scale energy storage applications.Here,cooperative ... The mitigation of sulphation and parasitic hydrogen evolution is considered as prominent research emphasis for the development of lead-carbon batteries(LCBs)in large-scale energy storage applications.Here,cooperative Pb-C composites consisting of single atom Pb and carbon-encapsulated PbO nanoparticles were prepared by freeze-drying technique and pyrolytic reduction to address above obstacles.The innovative use of Pb^(2+)to cross-link sodium alginate enabled a uniform distribution of Pb in the composites,generating Pb-C-PbO three-phase heterostructure.Experimental analysis and theoretical calculations revealed the synergistic interactions between single-atom Pb and PbO nanoparticles in suppressing parasitic hydrogen evolution and promoting the adsorption of Pb atoms.The presence of monatomic Pb and PbO enhanced the affinity of the composites for the negative active materials and facilitated the transformation of the active materials from bulk into spherical shapes to enhance the specific surface area,thereby counteracting sulphation.Through the coordinated integration of various functionalities offered by Pb@C-x,the cycle life of the battery at HRPSoC reaches 7025 cycles,which is two times for LCB with pure carbon materials.Additionally,the discharge capacity increased from 3.52 to 3.79 Ah.This study provides substantial insights into the construction of Pb-C composites for LCBs to inhibit negative sulphation and hydrogen evolution. 展开更多
关键词 Lead-carbon battery Negative sulphation Hydrogen evolution SINGLE-ATOM Lead carbon composites
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MiR-107-3p/Atp6v0e1 contributes to protective effects of two selenium-containing peptides,TSeMMM and SeMDPGQQ on lead-induced neurotoxicity
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作者 Yong Fang Tianhang Huang +5 位作者 Jian Wu Xieqi Luo Fengjiao Fan Peng Li Jian Ding Xinyang Sun 《Food Science and Human Wellness》 SCIE CAS CSCD 2024年第4期2060-2067,共8页
Two selenium(Se)-containing peptides from Se-enriched rice,TSeMMM and SeMDPGQQ,possess neuroprotective potency against lead(Pb2+)-induced cytotoxicity.However,the crosstalk between mRNA and microRNAs(miRNA)involved in... Two selenium(Se)-containing peptides from Se-enriched rice,TSeMMM and SeMDPGQQ,possess neuroprotective potency against lead(Pb2+)-induced cytotoxicity.However,the crosstalk between mRNA and microRNAs(miRNA)involved in the neuroprotection mechanism remains to be elucidated.In this study,RNA-sequencing and miRNA-sequencing were used to independently identify differentially expressed mRNAs and small RNAs profiles in Pb^(2+)-treated primary fetal rat cortical neurons and then the correlated miRNA-mRNA target pairs were obtained.It was found that 34 mRNAs related to oxidative phosphorylation could be reversed by pretreatment of TSeMMM and SeMDPGQQ.The protective effect of TSeMMM and SeMDPGQQ was mediated by upregulation of miR-107-3p,which downregulates the ATPase H+transporting V0 subunit e1(Atp6v0e1)mRNA level.A zebrafish model was applied to verify the relevance between the targeted mRNA and miRNA by real-time quantitative PCR.The results indicated that miR-107-3p was a potential therapeutic target to achieve neuroprotection of Se-containing peptides via stimulation of Atp6v0e1. 展开更多
关键词 LEAD Se-containing peptides NEUROPROTECTION miRNA
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Vacancy healing for stable perovskite solar cells via bifunctional potassium tartrate
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作者 Jing Dou Yue Ma +10 位作者 Xiuxiu Niu Wentao Zhou Xueyuan Wei Jie Dou Zhenhua Cui Qizhen Song Tinglu Song Huanping Zhou Cheng Zhu Yang Bai Qi Chen 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第1期64-70,I0002,共8页
Perovskite solar cell has gained widespread attention as a promising technology for renewable energy.However, their commercial viability has been hampered by their long-term stability and potential Pb leakage. Herein,... Perovskite solar cell has gained widespread attention as a promising technology for renewable energy.However, their commercial viability has been hampered by their long-term stability and potential Pb leakage. Herein, we demonstrate a bifunctional passivator of the potassium tartrate(PT) to address both challenges. PT minimizes the Pb leakage in perovskites and also heals cationic vacancy defects, resulting in improved device performance and stability. Benefiting from PT modification, the power conversion efficiency(PCE) is improved to 23.26% and the Pb leakage in unencapsulated films is significantly reduced to 9.79 ppm. Furthermore, the corresponding device exhibits no significant decay in PCE after tracking at the maximum power point(MPP) for 2000 h under illumination(LED source, 100 mW cm^(-2)). 展开更多
关键词 PEROVSKITE Potassium tartrate Lead leakage Long-term stability
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Epicatechin attenuates lead(Pb)-induced cognitive impairment in mice:regulation on Nrf2 signaling pathway,and interference on the interaction between Pb with albumin
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作者 Dai Cheng Qianqian Yu +2 位作者 Kexin Zhu Dingdong Bu Zijian Wu 《Food Science and Human Wellness》 SCIE CSCD 2024年第2期1065-1078,共14页
Epicatechin(EC)was used in this study to antagonize the cognitive dysfunction caused by lead(Pb)exposure in mice.Eight-week-old male Kunming mice were treated with PbCl_(2)(20 mg/kg)and/or EC(50 mg/kg)by gavage admini... Epicatechin(EC)was used in this study to antagonize the cognitive dysfunction caused by lead(Pb)exposure in mice.Eight-week-old male Kunming mice were treated with PbCl_(2)(20 mg/kg)and/or EC(50 mg/kg)by gavage administration for 4 weeks.Morris water maze test showed that EC could improve memory dysfunction induced by Pb.EC antagonized Ca^(2+)overload,activated Nrf2 signaling pathway and reduced the accumulation of Pb in the brain and serum,which suggested that EC might alter Pb distribution in mice.In vitro,spectroscopic analysis,potentiometric titration and docking studies were applied to inquiry into the interaction between bovine serum albumin(BSA)and Pb^(2+)in presence or absence of EC.EC was proved to chelate Pb^(2+)and reduced the interaction between BSA and Pb^(2+).In summary,EC might protect Pb-induced cognitive impairment by activating Nrf2 signaling pathway,and suppressing Pb accumulation via interference on the binding of Pb to albumin. 展开更多
关键词 LEAD EPICATECHIN Bovine serum albumin Interaction Oxidative stress
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