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Loss Factors and their Effect on Resonance Peaks in Mechanical Systems 被引量:1
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作者 Roman Vinokur 《Sound & Vibration》 EI 2023年第1期1-13,共13页
The loss factors and their effects on the magnitude and frequency of resonance peaks in various mechanical sys-tems are reviewed for acoustic,vibration,and vibration fatigue applications.The main trends and relationsh... The loss factors and their effects on the magnitude and frequency of resonance peaks in various mechanical sys-tems are reviewed for acoustic,vibration,and vibration fatigue applications.The main trends and relationships were obtained for linear mechanical models with hysteresis damping.The well-known features(complex module of elasticity,total loss factor,etc.)are clarified for practical engineers and students,and new results are presented(in particular,for 2-DOF in-series models with hysteresis friction).The results are of both educational and prac-tical interest and may be applied for NVH analysis and testing,mechanical and aeromechanical design,and noise and vibration control in buildings. 展开更多
关键词 Mechanical loss factor resonance peak ACOUSTICS VIBRATION structural failure noise NVH engineering systems
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New Resolution to Coupling Loss Factor of Beam Plate Structure
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作者 刘景泉 姚德源 《Journal of Beijing Institute of Technology》 EI CAS 2000年第3期267-272,共6页
The transmission of transverse vibrational energy of a vertically rigid beam plate coupled structure is analyzed to get the theoretical results of coupling loss factor(CLF), a very important parameter in statistical ... The transmission of transverse vibrational energy of a vertically rigid beam plate coupled structure is analyzed to get the theoretical results of coupling loss factor(CLF), a very important parameter in statistical energy analysis(SEA). The modal analysis method is used to discuss the vibration energy of the typical model, as well as the power flow between the two subsystems. Furthermore, the resolution to the coupling loss factor is also derived and compared with the measured values. The analytical results of the coupling loss factor agree with the measured ones fully, this new resolution is significant for the application of SEA. 展开更多
关键词 statistical energy analysis coupling loss factor modal analysis method
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Simulation of higher order modes and loss factor of a new type of 500-MHz single cell superconducting cavity at SSRF 被引量:2
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作者 YU Haibo LIU Jianfei +5 位作者 HOU Hongtao LU Changwang WEI Yelong MA Zhenyu FENG Ziqiang MAO Dongqing 《Nuclear Science and Techniques》 SCIE CAS CSCD 2011年第5期257-260,共4页
In this paper,higher order modes(HOMs) and loss factor of a new type of 500-MHz superconducting cavity is studied,by simulating its broadband HOMs damping at different positions of the ferrite HOM-absorber and differe... In this paper,higher order modes(HOMs) and loss factor of a new type of 500-MHz superconducting cavity is studied,by simulating its broadband HOMs damping at different positions of the ferrite HOM-absorber and different lengths of the ferrite.The results show that the impedance and Q value of the HOMs in transverse and longitudinal modes could be greatly reduced.The HOM longitudinal impedance could be damped to meet the requirement of SSRF beam instability threshold.The calculated loss factor of the new SC cavity was compared with cavities at SSRF.It was estimated that the HOM absorber could absorb a total power of 3.16 kW at 4-mm beam bunch length. 展开更多
关键词 损耗因子 高阶模 超导腔 光源 上海 模拟 单细胞 纵向阻抗
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On-line Monitoring of Insulation Dielectric Loss Factor Based on Balance Principle
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作者 Tianxiang CHEN Zhenhua SHAO +1 位作者 Shaozhen QIN Hong TIAN 《电力系统自动化》 EI CSCD 北大核心 2013年第21期180-183,共4页
关键词 介质损耗因数 平衡原则 在线监测 绝缘 相位误差 高精确度 电流传感器 位移传感器
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Identification of Modal Loss Factor of a Sandwich Composite Structure with Polyethylene Terephthalate Core in the Aspect of Core Properties Determination
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作者 Krzysztof Marynowski Katarzyna Grochowska 《Materials Sciences and Applications》 2015年第6期473-488,共16页
Comparison of the loss factor determination methods of the sandwich composite structure with polyethylene terephthalate core in the aspect of core material rheological parameters identification was the purpose of the ... Comparison of the loss factor determination methods of the sandwich composite structure with polyethylene terephthalate core in the aspect of core material rheological parameters identification was the purpose of the study. Three frequency bandwidths n dB: 1 dB, 2 dB, 3 dB methods, the resonant amplitude method and the fit method of the response of the one degree of freedom model system are taken into considerations. Identification procedure, according to ASTM E756-2005 [1] based on experimental studies of the forced vibrations of the composite structure was presented in the paper. To determine the function of the complex shear modulus of the core material, the Nelder-Mead method is applied. Shear modulus and loss factor identification results were presented on the plots in the frequency domain. The results in a quantitative manner set the applied methods and their practical utility in order. 展开更多
关键词 Composite Material RHEOLOGICAL Fractional Model VISCOELASTICITY loss factor Shear MODULUS
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Investigation of Pile Construction and Productivity Loss: An Analysis of Macro Impact Factor
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作者 Minhaz Ahmed Wang Xu 《World Journal of Engineering and Technology》 2023年第4期932-964,共33页
Pile foundations are challenging to build due to subsurface obstacles, contractor ignorance, and difficulties with site planning. Given the unpredictable environment of the construction site, productivity losses durin... Pile foundations are challenging to build due to subsurface obstacles, contractor ignorance, and difficulties with site planning. Given the unpredictable environment of the construction site, productivity losses during pile work are to be thought possible. Prior to finishing a site pre-investigation, a foundation’s area is usually sampled for statistical reasons. There are studies on pile construction outside of Bangladesh that are supported by relevant empirical data in the literature. Since Bangladesh, which is regarded as a third-world country, is ignored in this regard, the literature currently available about pile building and the associated productivity loss is unable to provide adequate information or appropriate empirical data. Due to this pile-building sector in Bangladesh has been experiencing a decline in production for quite some time now. Before attempting to increase productivity in pile construction, it is essential to investigate the potential losses and the variables that might have an influence. This study aims to accomplish the following objectives: 1) identify the primary factors that have an impact on pile construction;2) develop an SVR model that accurately predicts productivity loss;and 3) figure out the projected loss by basing it on the historical scenario that is the most comparable to the current one. A Support Vector Regression (SVR) model was developed after a study of the relevant literature. This model enabled the collection of 110 pile building projects from five significant locations in Bangladesh. The model was constructed using a list of eight inputs in addition to a list of five macro elements (labor, management, environment, material, and equipment) (soil condition, pile type, pile material, project size, project location, pile depth, pile quantity, and equipment quantity). Using 10-way cross validation, the SVR achieves an accuracy of 87.2% in its predictions. On the basis of what has occurred in the past, we are able to estimate that there will be a loss of around 18.55 percent of the total output. A new perspective for engineers studying the delay factors with productivity loss is provided by the outcome of important tasks as it relates to loss in productivity and overall factors faced. In the building construction industry, effective management should place more emphasis on the correlation between productivity loss and the factors that cause it. Therefore, to represent the effect on productivity loss, real factors can be summed up as a decline in productivity loss. The findings of the study would urge specialists to concentrate on waste as a means of increasing overall production. 展开更多
关键词 Productivity loss Macro-Effect factor Pile Construction Regression Model SVR Model
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Navigating Silence: A Comprehensive Review of Parental Roles in the Rehabilitation of Children with Hearing Loss
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作者 Kondwani Hamanjila Marirajan Thiruppathi Harrison Phiri 《Open Journal of Pediatrics》 2024年第2期364-378,共15页
This narrative literature review delves into the multifaceted realm of parental involvement in the rehabilitation of children with permanent hearing loss. While existing research has made strides in elucidating parent... This narrative literature review delves into the multifaceted realm of parental involvement in the rehabilitation of children with permanent hearing loss. While existing research has made strides in elucidating parental roles in this context, critical gaps persist, necessitating a comprehensive exploration to inform future endeavors. Our review synthesizes a wide array of studies, identifying these gaps and emphasizing the significance of addressing them. Themes emerging from the literature include the varying degrees of parental engagement, the impact of cultural and socio-economic factors, and the challenges faced by families navigating rehabilitation processes. The synthesis of this literature not only highlights the current state of knowledge but also provides a roadmap for future research efforts. By addressing these gaps, we aim to contribute to a more nuanced understanding of parental involvement in the rehabilitation of children with permanent hearing loss, ultimately fostering improved support systems and holistic care for affected families. 展开更多
关键词 Parental Involvement REHABILITATION CHILDREN Permanent Hearing loss Socioeconomic factors Cultural Influences
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Analysis of the causes of formation of negative loss factors 被引量:4
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作者 SUN Zhaohui SUN Jincai WANG Chong and SHENG Meiping(Institute of Acoustic Engineering, Northwestern Polytechnical University Xi’an, 710072) 《Chinese Journal of Acoustics》 1996年第3期239-246,共8页
Based on classical energy balance equations for two coupled systems in Statistical Energy Analyis (SEA), the possibility of causing negative loss factors in measuring SEA parameters by using the equations is analyzed.... Based on classical energy balance equations for two coupled systems in Statistical Energy Analyis (SEA), the possibility of causing negative loss factors in measuring SEA parameters by using the equations is analyzed. The physical causes of formation of negative loss factors are theoretically invstigated by vibration analysis of the two non-conservatively coupled oscillator sets. Mom the analytical results, it is shown that the necessary condition of foedng negatbo loss factors is that the coupling of the coupled systems is non-conservative and strong and the suffiient condition is that the excitation frequency of the external force is not equal to the natural frequencies of the two oscillators at the sam tAne or the parameters of the two oscillators are much different. The absolute values of the negative loss factors increase with the increase of the coupling pararneters. 展开更多
关键词 SEA Negative loss factor SEA parameters
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The coupling loss factors for non-conservatively coupled structures 被引量:3
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作者 SHENG Meiping(Institute of Acoustic Enmneering, Northwestern Polytechnzcal Uniuersity Xi’an 710072)Wang Minqing(Institute of Vibration and Noise Control, Xi ’an Jiaotong University Xi’an’ 710049)SUN Jincai(Institute of Aconstic Engineering, Northwestern P 《Chinese Journal of Acoustics》 1998年第4期299-306,共8页
The method to calculate the coupling loss factors for non-conservatively coupled structures by using the mobilities of substructures is studied. By using the form of the energy balance equations of conservatively coup... The method to calculate the coupling loss factors for non-conservatively coupled structures by using the mobilities of substructures is studied. By using the form of the energy balance equations of conservatively coupled systems, the relationship between the coupling loss factors and the energy ratios in non-conservatively coupled systems is derived. The method to calculate the energy ratios by using the mobilities of substructures is introduced, and experiment verification is carried out. The test data agree well with the predicted results. 展开更多
关键词 ACTA The coupling loss factors for non-conservatively coupled structures
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Power Transformer No-Load Loss Prediction with FEM Modeling and Building Factor Optimization 被引量:2
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作者 Ehsan Hajipour Pooya Rezaei +1 位作者 Mehdi Vakilian Mohsen Ghafouri 《Journal of Electromagnetic Analysis and Applications》 2011年第10期430-438,共9页
Estimation of power transformer no-load loss is a critical issue in the design of distribution transformers. Any deviation in estimation of the core losses during the design stage can lead to a financial penalty for t... Estimation of power transformer no-load loss is a critical issue in the design of distribution transformers. Any deviation in estimation of the core losses during the design stage can lead to a financial penalty for the transformer manufacturer. In this paper an effective and novel method is proposed to determine all components of the iron core losses applying a combination of the empirical and numerical techniques. In this method at the first stage all computable components of the core losses are calculated, using Finite Element Method (FEM) modeling and analysis of the transformer iron core. This method takes into account magnetic sheets anisotropy, joint losses and stacking holes. Next, a Quadratic Programming (QP) optimization technique is employed to estimate the incomputable components of the core losses. This method provides a chance for improvement of the core loss estimation over the time when more measured data become available. The optimization process handles the singular deviations caused by different manufacturing machineries and labor during the transformer manufacturing and overhaul process. Therefore, application of this method enables different companies to obtain different results for the same designs and materials employed, using their historical data. Effectiveness of this method is verified by inspection of 54 full size distribution transformer measurement data. 展开更多
关键词 BUILDING factor CORE lossES FINITE ELEMENT Method Power Transformer
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Activation of hypoxia-inducible factor 1 attenuates periapical inflammation and bone loss 被引量:22
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作者 Kimito Hirai Hisako Furusho +1 位作者 Kiichi Hirota Hajime Sasaki 《International Journal of Oral Science》 SCIE CAS CSCD 2018年第2期92-101,共10页
Hypoxia(low oxygen level) is an important feature during infections and affects the host defence mechanisms. The host has evolved specific responses to address hypoxia, which are strongly dependent on the activation... Hypoxia(low oxygen level) is an important feature during infections and affects the host defence mechanisms. The host has evolved specific responses to address hypoxia, which are strongly dependent on the activation of hypoxia-inducible factor 1(HIF-1).Hypoxia interferes degradation of HIF-1 alpha subunit(HIF-1α), leading to stabilisation of HIF-1α, heterodimerization with HIF-1 beta subunit(HIF-1β) and subsequent activation of HIF-1 pathway. Apical periodontitis(periapical lesion) is a consequence of endodontic infection and ultimately results in destruction of tooth-supporting tissue, including alveolar bone. Thus far, the role of HIF-1 in periapical lesions has not been systematically examined. In the present study, we determined the role of HIF-1 in a wellcharacterised mouse periapical lesion model using two HIF-1α-activating strategies, dimethyloxalylglycine(DMOG) and adenovirusinduced constitutively active HIF-1α(CA-HIF1 A). Both DMOG and CA-HIF1 A attenuated periapical inflammation and tissue destruction. The attenuation in vivo was associated with downregulation of nuclear factor-κappa B(NF-κB) and osteoclastic gene expressions. These two agents also suppressed NF-κB activation and subsequent production of proinflammatory cytokines by macrophages. Furthermore, activation of HIF-1α by DMOG specifically suppressed lipopolysaccharide-stimulated macrophage differentiation into M1 cells, increasing the ratio of M2 macrophages against M1 cells. Taken together, our data indicated that activation of HIF-1 plays a protective role in the development of apical periodontitis via downregulation of NF-κB, proinflammatory cytokines, M1 macrophages and osteoclastogenesis. 展开更多
关键词 CA Activation hypoxia-inducible factor attenuates periapical inflammation bone loss HIF
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Factor value determination and applicability evaluation of universal soil loss equation in granite gneiss region
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作者 Wen-hai ZHANG Xing-nan ZHANG Zhi-dong GAO 《Water Science and Engineering》 EI CAS 2009年第2期87-97,共11页
Six types of runoff plots were set up and an experimental study was carried out to examine natural rate of soil and water loss in the granite gneiss region of northern Jiangsu Province in China. Through correlation an... Six types of runoff plots were set up and an experimental study was carried out to examine natural rate of soil and water loss in the granite gneiss region of northern Jiangsu Province in China. Through correlation analysis of runoff and soil loss during 364 rainfall events, a simplified and convenient mathematical formula suitable for calculating the rainfall erosivity factor (R) for the local region was established. Other factors of the universal soil loss equation (USLE model) were also determined. Relative error analysis of the soil loss of various plots calculated by the USLE model on the basis of the observed values showed that the relative error ranged from -3.5% to 9.9% and the confidence level was more than 90%. In addition, the relative error was 5.64% for the terraced field and 12.36% for the sloping field in the practical application. Thus, the confidence level was above 87.64%. These results provide a scientific basis for forecasting and monitoring soil and water loss, for comprehensive management of small watersheds, and for soil and water conservation planning in the region. 展开更多
关键词 granite gneiss region soil erosion universal soil loss equation factor value applicability evaluation
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Analysis on the Influence Factors of Capacitor Voltage Transformer Dielectric Loss Measurement
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作者 Yongdong Li Qing-da Meng +3 位作者 Po Yang Zheyuan Zhao Wei Zhang Zhuo Pan 《Energy and Power Engineering》 2013年第4期1240-1242,共3页
Capacitor voltage transformer (CVT), which is with simple structure, convenient maintenance, functional diversity and high impact pressure strength, is widely used. And its capacitance and dielectric loss Angle measur... Capacitor voltage transformer (CVT), which is with simple structure, convenient maintenance, functional diversity and high impact pressure strength, is widely used. And its capacitance and dielectric loss Angle measurement is an important test on testing the insulation of the equipment. This paper is mainly to introduce and discuss one of the CVT test methods——the “self excitation method”, combined with the actual situation encountered in the work, sums up and expounds the maintenance of CVT and preventive test of influence factors. 展开更多
关键词 Capacitive VOLTAGE TRANSFORMER DIELECTRIC loss the Influencing factorS
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Effects of Orlistat - induced Weight Loss on Cardiovascular Risk Factors in Obese Chinese Subjects
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作者 徐明彤 吴木潮 +3 位作者 黎锋 周淑娴 程桦 傅祖植 《South China Journal of Cardiology》 CAS 2003年第1期1-4,共4页
Objectives To observe the influence of weight loss induced by orlistat on several cardiovascular diseases risk factors in obese Chinese subjects. Methods Sixty obese Chinese patients participated in a 24 week clinical... Objectives To observe the influence of weight loss induced by orlistat on several cardiovascular diseases risk factors in obese Chinese subjects. Methods Sixty obese Chinese patients participated in a 24 week clinical trial. Participants were prescribed a slightly hypocaloric diet and exercise, then they were randomly assigned double -blind treatment with either orlistat 120 mg three times a day or placebo. Their body weight, blood pressure, fasting glucose, insulin, HbA1c, and serum lipid profile were performed before and after the weight loss intervention. Results After 24 weeks, orlistat -treated group lost more of their body weight than placebo group (6. 66 ± 0. 52 kg, 8. 44±4.08% and 1. 98 ± 0. 44 kg, 2. 44±1. 74 % , respectively, P < 0. 05) . Moreover, after treatment, orlistat - treated patients showed significant decreases in serum levels of total cholesterol, low density lipoprotein - cholesterol and high density lipoprotein - cholesterol ( P < 0.01), but in placebo group we found no change. Both systolic blood pressure and diastolic blood pressure fell significantly in orlistat - treated group. Fasting glucose and HOMA - IR in orlistat - treated group was distinctly reduced if compared with placebo group. Conclusions Weight loss resulting from orlistat treatment and slightly hypocaloric diet has produced favorable effects on several cardiovascular risk factors in obese Chinese subjects. 展开更多
关键词 Orlistat Weight loss Cardiovascular risk factors
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三电平辅助变流器寿命优化控制 被引量:2
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作者 向超群 杜京润 +3 位作者 孙士杰 李佳怡 范子寅 于天剑 《铁道科学与工程学报》 EI CAS CSCD 北大核心 2024年第1期328-341,共14页
辅助变流系统是动车组车辆上关键的电气组成部分,主要为空调机组、风机、照明等交流负载提供稳定的三相电源。结温是影响动车组三电平辅助变流器IGBT(Insulated-gate Bipolar Transistor)模块寿命的主要因素。为了提高动车组三电平中点... 辅助变流系统是动车组车辆上关键的电气组成部分,主要为空调机组、风机、照明等交流负载提供稳定的三相电源。结温是影响动车组三电平辅助变流器IGBT(Insulated-gate Bipolar Transistor)模块寿命的主要因素。为了提高动车组三电平中点钳位(Neutral-Point Clamped,NPC)型辅助变流器寿命,提出一种降低结温的模型预测电流控制(Model Predictive Current Control,MPCC)策略。首先,考虑传统MPCC在每个采样周期需要代入27个电压矢量循环计算,计算量较大,因此将三电平基本电压矢量划分在间隔60°的6个扇区中,通过计算电压矢量在两相静止坐标下的相角,进而判断参考电压矢量所处扇区,将备选矢量数目从27缩减至10,减少了计算量;其次,传统MPCC直接应用于动车组辅助变流器会使IGBT模块的结温较高,老化速度加快,对变流器安全稳定运行产生不可预测的损害,本文对IGBT模块的开关损耗和导通损耗进行近似等效,得到了和集射极电压、集电极电流相关的功率损耗因子。通过预测每相电流的方向,进而预测IGBT模块的开关和导通情况,动态加入功率损耗因子,并在代价函数中约束每相IGBT及其续流二极管(Free Wheeling Diode,FWD)的功率损耗,使得最优电压矢量在降低功率损耗的同时保证一定的控制性能。通过仿真与实验验证,本文所提方法相比传统MPCC策略降低了功率器件的结温,提高了变流器寿命。 展开更多
关键词 三电平中点钳位型辅助变流器 功率损耗 模型预测电流控制 损耗因子 变流器寿命
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考虑时间变化的洪涝灾害损失评估 被引量:2
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作者 王浩 赵铜铁钢 +3 位作者 田雨 陈泽聪 郑炎辉 陈晓宏 《水利学报》 EI CSCD 北大核心 2024年第2期127-136,共10页
洪涝灾害是对我国影响最大的自然灾害之一。聚焦灾害损失评估问题,本文构建了考虑时间变化的洪涝灾害损失函数。一方面,表征灾害损失随着致灾因子强度先递增、而后增幅趋缓的静态S型曲线关系;另一方面,通过量级、形状和位置三个参数综... 洪涝灾害是对我国影响最大的自然灾害之一。聚焦灾害损失评估问题,本文构建了考虑时间变化的洪涝灾害损失函数。一方面,表征灾害损失随着致灾因子强度先递增、而后增幅趋缓的静态S型曲线关系;另一方面,通过量级、形状和位置三个参数综合考虑灾害损失随时间的动态变化情况。基于《中国水旱灾害防御公报》提供的受灾人口、直接经济损失数据,对于各省级行政区2006—2021年洪涝灾害损失进行评估分析。结果表明:通过拟合洪涝灾害损失函数,洪涝灾害损失关于致灾因子强度和时间的三维空间散点图可有效地拓展成为连续的三维空间曲面及二维空间热力图。各省级行政区受灾人口整体上呈现出逐年下降的特征,但随致灾因子强度的增加而趋于增加。各省级行政区直接经济损失则表现出明显的差异,随时间呈现出大幅下降、缓慢下降和略有增加等不同特征。考虑时间变化的洪涝灾害损失函数是变化环境下灾害评估的有效工具,可为区域洪涝灾情评估提供借鉴和参考。 展开更多
关键词 洪涝灾害 致灾因子 损失函数 受灾人口 直接经济损失 非一致性
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Sensitivity of Pion versus Parton-Jet Nuclear Modification Factors to the Path-Length Dependence of Jet-Energy Loss at RHIC and LHC
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作者 Barbara Betz Miklos Gyulassy 《Chinese Physics Letters》 SCIE CAS CSCD 2015年第12期30-34,共5页
We compare the jet-path length and beam-energy dependence of the pion nuclear modification factor and a patton-jet nuclear modification factor at RHIC and LHC, and contrast the predictions based on a linear pQCD and a... We compare the jet-path length and beam-energy dependence of the pion nuclear modification factor and a patton-jet nuclear modification factor at RHIC and LHC, and contrast the predictions based on a linear pQCD and a highly non-linear hybrid AdS holographic model of jet-energy loss. It is found that both models require a reduction of the jet-medium coupling from RHIC to LHC to account for the measured pion nuclear modification factor. In the case of the parton-jet nuclear modification factor, however, which serves as a lower bound for the LO jet nuclear modification factor of reconstructed jets, the extracted data can be characterized without a reduced jet-medium coupling at LHC energies. It is concluded that when the reconstructed jets are sensitive to both quarks and gluons and thus provide more information than the pion nuclear modification factor, their information regarding the jet-medium coupling is limited due to the superposition with NLO and medium effects. Hence, a detailed description of the underlying physics requires both the leading hadron and the reconstructed jet nuclear modification factor. Unfortunately, the results for both the pion and the parton-jet nuclear modification factor are insensitive to the jet-path dependence of the models considered. 展开更多
关键词 LHC Sensitivity of Pion versus Parton-Jet Nuclear Modification factors to the Path-Length Dependence of Jet-Energy loss at RHIC and LHC
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Selective deletion of the soluble Colony-Stimulating Factor 1 isoform in vivo prevents estrogen-deficiency bone loss in mice
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作者 Gang-Qing Yao Nancy Troiano +1 位作者 Christine A Simpson Karl L Insogna 《Bone Research》 SCIE CAS CSCD 2017年第4期367-374,共8页
Neutralizing CSF1 in vivo completely prevents ovariectomy (OVX)-induced bone loss in mice. There are two isoforms of CSF1, soluble (sCSF1), and membrane-bound (mCSF1), but their individual biological functions a... Neutralizing CSF1 in vivo completely prevents ovariectomy (OVX)-induced bone loss in mice. There are two isoforms of CSF1, soluble (sCSF1), and membrane-bound (mCSF1), but their individual biological functions are unclear. It had been previously reported that mCSF1 knockout (K/O) and wild type (Wt) female mice experience the same degree of bone loss following OVX. In Wt mice the expression of sCSF1 was elevated fourfold in skeletal tissue following OVX while expression of mCSF1 was unchanged. To examine the role of sCSF1 in OVX-induced bone loss, mice were engineered in which sCSF1 was not expressed but expression of mCSF1 was unaffected (sCSF1 K/O). Isoform-specific reverse transcription PCR confirmed the absence of transcripts for sCSF1 in bone tissue isolated from these animals and no circulating CSF1 was detected by ELISA. Surprisingly, there were no significant differences in bone mineral density (BMD) between sCSF1 K/O mice and Wt controls as assessed by dual-energy X-ray absorptiometry and micro-CT. However, one month after OVX, femoral, spinal and total BMD had declined by 11.2%, 8.9%, and 8.7% respectively in OVX-Wt animals as compared to Sham-OVX. In contrast OVX sCSF1 K/O mice showed changes of +0.1%, - 2.4%, and +2.3% at the same 3 sites compared to Sham-OVX sCSF1 K/O mice. These data indicate important non-redundant functions for the two isoforms of CSF1 and suggest that sCSF1, but not mCSF1, plays a key role in estrogen-deficiency bone loss. 展开更多
关键词 CSF Selective deletion of the soluble Colony-Stimulating factor 1 isoform in vivo prevents estrogen-deficiency bone loss in mice
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湿热环境苯基阻尼硅橡胶加速老化与寿命预测研究
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作者 张欢 徐弘达 +1 位作者 许文 赵云峰 《宇航材料工艺》 CAS CSCD 北大核心 2024年第2期130-135,共6页
研究了苯基阻尼硅橡胶的湿热老化过程,重点考察了其拉伸性能、阻尼性能和压缩回弹性能。对于拉伸性能,实验研究表明材料拉伸模量和100%定伸应力均随着温度或者湿度的上升而逐渐提高。对于阻尼性能,损耗系数随着温度或者湿度的上升而逐... 研究了苯基阻尼硅橡胶的湿热老化过程,重点考察了其拉伸性能、阻尼性能和压缩回弹性能。对于拉伸性能,实验研究表明材料拉伸模量和100%定伸应力均随着温度或者湿度的上升而逐渐提高。对于阻尼性能,损耗系数随着温度或者湿度的上升而逐渐下降。对于压缩回弹性能,压缩永久变形随着温度或者湿度的上升而逐渐上升。另外,温度对苯基硅橡胶性能的影响大于湿度。这主要归因于老化过程中同时发生了侧基氧化和水解,进而导致分子链交联和断裂同时发生。相比于分子链断裂,分子链交联占据了主导作用。最后,采用Peck模型预测了不同温湿度环境下苯基硅橡胶的贮存寿命。由于阻尼性能决定了苯基硅橡胶的减振性能,因此将损耗系数作为评价特征参数。结果表明,在25℃下,当相对湿度在80%~40%间变动时,苯基硅橡胶的寿命在18~39 a间变化。此研究有助于进一步理解苯基硅橡胶的老化过程,并且提供了不同湿热环境下苯基阻尼硅橡胶寿命预测的方法。 展开更多
关键词 苯基阻尼硅橡胶 损耗系数 湿热加速 寿命预测
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电气设备剩余电压测试仪校准方法
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作者 冯建 胡俊杰 +1 位作者 许峰 周碧红 《计量学报》 CSCD 北大核心 2024年第5期626-630,共5页
分析了电气设备剩余电压测试仪基本原理,提出一种基于标准阻容网络法对剩余电压测试仪剩余电压幅值和延迟时间参数进行校准的方法。结合交流标准电阻器和电容器等效模型,分析了标准电阻时间常数和标准电容损耗因数对校准结果的影响,推... 分析了电气设备剩余电压测试仪基本原理,提出一种基于标准阻容网络法对剩余电压测试仪剩余电压幅值和延迟时间参数进行校准的方法。结合交流标准电阻器和电容器等效模型,分析了标准电阻时间常数和标准电容损耗因数对校准结果的影响,推导了校准时剩余电压和延迟时间标准值的计算方法。采用1 MΩ交流标准电阻和1μF标准电容器组成的电路网络对剩余电压测试仪进行了校准,结果表明标准阻容网络法可满足该仪器的校准。对测量结果进行了不确定度分析,剩余电压幅值测量不确定度为1.1%,延迟时间测量不确定度为1.2%,主要不确定度分量为标准电容器损耗因数的影响。 展开更多
关键词 电学计量 剩余电压 延迟时间 阻容网络 损耗因数 不确定度
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