The earliest Ben Cao Jing(Classics of Materia Medica;25 C.E.–220 C.E.)appeared during the reign of the Han Dynasty(202 B.C.E.–220 C.E.);their origins are traceable to the religious group called Fang Xian Dao.In addi...The earliest Ben Cao Jing(Classics of Materia Medica;25 C.E.–220 C.E.)appeared during the reign of the Han Dynasty(202 B.C.E.–220 C.E.);their origins are traceable to the religious group called Fang Xian Dao.In addition to their use as a medical reference,the Ben Cao Jing works were also used for religious purposes.Tao Hongjing(456 C.E.–536 C.E.),a famous doctor and Daoist(one member of the Chinese local religion,Daoism)of the Liang Dynasty(502 C.E.–557 C.E.),compiled the Ben Cao Jing Ji Zhu(Variorum of Classics of Materia Medica;456 C.E.–536 C.E.)based on the Shen Nong Ben Cao Jing(Shennong’s Classic of Materia Medica;25 C.E.–220 C.E.).During the compilation of this book,Tao made a radical medical revision to the Shen Nong Ben Cao Jing,by reducing its religious contents while complementing its medical contents.After such revisions,the ancient Ben Cao Jing was transformed from a religious manual into an herbal pharmacopoeia.展开更多
Bencao Tujing(Illustrated Classic of Materia Medica)is a brilliant and monumental compendium of materia medica by Su Song,which was published in 1061 and gathered ancestral knowledge from the Song dynasty as a legacy ...Bencao Tujing(Illustrated Classic of Materia Medica)is a brilliant and monumental compendium of materia medica by Su Song,which was published in 1061 and gathered ancestral knowledge from the Song dynasty as a legacy for posterity.The compendium emphasized the clinical applications of medicinal materials collected nationwide,which used illustrated atlases as references.The descriptions for each medicinal material subsumed the prescriptions containing it and were supplemented with relevant medical cases.Medical prescriptions predating the Song dynasty were included,which enhanced the clinical usefulness of the pharmacopoeia.The ancestral knowledge of materia medica was extensively merged with natural history throughout the compendium,which also made extensive reference to more than 200 Chinese classics,local gazetteers,and published works from the social and natural sciences.The inclusion of natural history and literature works changed the convention used in earlier pharmacopoeias to present medicines based solely on pharmacological analyses.The compendium also pioneered the inclusion of natural history in pharmacopoeia.Bencao Tujing helped establish China’s leading position in the field of materia medica.Su Song’s meticulous nature,truth-seeking attitude,and adherence to scientific thinking are truly worthy of emulation and promotion.展开更多
This paper tests the hypothesis that the commentary trend of the Shen Nong Ben Cao Jing(Shen Nong’s Classic of the Materia Medica)arises alongside the fashionable philology of the time,or the aversion against the Jin...This paper tests the hypothesis that the commentary trend of the Shen Nong Ben Cao Jing(Shen Nong’s Classic of the Materia Medica)arises alongside the fashionable philology of the time,or the aversion against the Jin-Yuan medical philosophy.After surveying 12 major commentaries,it is concluded that the situation is more complicated than a simple assertion.The seemingly opposite philosophy and philology approaches have been used eclectically to innovate the understanding of ancient traditional Chinese medicine texts.展开更多
The Silk Road stretched over land and across seas connecting Europe,Africa,and Asia.The trade of medicine along these routes has had profound impacts on the populations and traditions they have come into contact with....The Silk Road stretched over land and across seas connecting Europe,Africa,and Asia.The trade of medicine along these routes has had profound impacts on the populations and traditions they have come into contact with.Chinese Medicine is no exception as it has taken numerous nonnative products and incorporated them into the unique philosophical construct of systematic correspondences that govern its practice.By looking at the four categories of primary source materials and studying the history of medical exchange along the Silk Road,we can determine how and where this information is used in Chinese Medicine.The Materia Medica(ben cao本草)texts are the first source of information for this study that will explore multiple sources to better understand the development of Chinese Medicine in relation to the rest of the world.展开更多
The search for possible effective local therapeutic agents led to the discovery of a plant that was later known as Fungus Melitensis.This parasitic flowering plant was initially believed to grow only on a small islet ...The search for possible effective local therapeutic agents led to the discovery of a plant that was later known as Fungus Melitensis.This parasitic flowering plant was initially believed to grow only on a small islet off Gozo known variably as General's or Fungus Rock.It is now known to be more widely distributed with a range extending from the Canary Islands to China.First mentioned in 1647 by the Maltese historian Gian Francesco Abela,the plant was later described and illustrated in 1674 by the Palermo botanist Paolo Boccone,while a detailed clinical treatise was prepared in 1689 by the Maltese physician Gio Francesco Bonamico.Based on the principles of the“doctrine of signatures,”the plant was considered useful by virtue of its color in conditions involving bleeding,while on the basis of the phallic appearance,it was considered efficacious for venereal disease.The medicinal properties of the plant became renowned throughout the European continent,increasing the demand for its collection and export.Measures were introduced to limit the collection to authorized individuals while physical access to the islet was made more difficult by cutting away the sloping parts of the islet.The plant lost its medicinal reputation during the early decades of the 19^th century and has now been relegated to the annals of medical history and folklore,though it is still designated a protected species.展开更多
Ben Cao Gang Mu Ying Jiao Dui Zhao(《本草纲目影校对照》A Contrast between the Photocopy and Collation of Compendium ofMateria Medica),completed by Zhang Zhibin and Zheng Jinsheng,is the latest variorum on Ben Cao Gang...Ben Cao Gang Mu Ying Jiao Dui Zhao(《本草纲目影校对照》A Contrast between the Photocopy and Collation of Compendium ofMateria Medica),completed by Zhang Zhibin and Zheng Jinsheng,is the latest variorum on Ben Cao Gang Mu(《本草纲目》Compendium ofMateria Medica).Adopting five different Jinling editions as the master copy,the book carefully collates the complex contents on the original book by contrasting the photocopies with the supplement and correction,which makes it easy to use.What is more,full-form punctuation is used to mark the reference books and proper nouns,which is a big success feat in the research history of Ben Cao Gang Mu.展开更多
The property theory of Chinese materia medica is one of the foundations of traditional Chinese medicine.The property of Chinese materia medica(PCMM)is a multi-dimensional expression of the effect of Chinese materia me...The property theory of Chinese materia medica is one of the foundations of traditional Chinese medicine.The property of Chinese materia medica(PCMM)is a multi-dimensional expression of the effect of Chinese materia medica(CMM),and it is related to the clinical prescription that fully reflects the clinical effect evaluation of CMM in a holistic,systematic,and scientific way.This paper discusses the source,development,and application of the PCMM by considering not only the five dimensions that constitute the PCMM but also the recognition of the human body and disease as given in traditional Chinese medicine.This paper aims to provide theoretical guidance for the rational use and development of CMM.展开更多
In ancient China, Daoist philosophers developed the concepts of qi(energy), Wu Xing(five elements), and yin(feminine, dark, negative) and yang(masculine, bright, positive) opposite forces between 200 and 600 BCE. Base...In ancient China, Daoist philosophers developed the concepts of qi(energy), Wu Xing(five elements), and yin(feminine, dark, negative) and yang(masculine, bright, positive) opposite forces between 200 and 600 BCE. Based on these philosophies, Zhen Jiu(acupuncture), Ben Cao(materia medica), and the practice of Qi Gong(energy optimization movements) evolved as the three interrelated therapeutic regimens of Chinese medicine(Note 1). Since the time of Zhang Qian, who discovered China's western regions in the 1st century BCE, Hai Yao(the exotic elements of materia medica from the maritime Silk Road countries), had been transmitted from the ancient land and maritime routes of the Silk Road to China in the past two millennia(Note 2). Since the late 17th century, the English East India Company, later called the British East India Company, introduced Yang Yao(opium) to the Manchu Qing Empire to balance a growing trade deficit for tea export from China to the British Empire. After the First Opium War ended in 1842, enterprising expatriate chemists and druggists in the treaty ports imported Xi Yao(modern medicines from the Western world) for sale to the merchant navy and the local market. From the second half of the 19th century onwards, both Hai Yao and Xi Yao have become a fully integrated part of modern China's armamentarium for the Chinese medicine and Western hospitals and retail pharmacy sectors. This paper articulates the journey of adoption of exotic elements of materia medica from the ancient land and sea routes of the Silk Road, including the western regions and the rest of the world in the past two millennia. Opium traders, ship surgeons, medical and pharmaceutical missionaries, enterprising traders, and policymakers together transformed Ben Cao into Xi Yao during the late Manchu Qing dynasty and the early Nationalist Era.展开更多
P-glycoprotein(P-gp)is an important transmembrane ATP-binding cassette(ABC)drug efflux transporter expressed in various human tissues such as the intestines,liver,kidneys,and bloodbrain barrier.It limits the intracell...P-glycoprotein(P-gp)is an important transmembrane ATP-binding cassette(ABC)drug efflux transporter expressed in various human tissues such as the intestines,liver,kidneys,and bloodbrain barrier.It limits the intracellular concentration of xenobiotics by pumping them out of the cells,affecting drug pharmacokinetics and therapeutic effects.With its broad substrate specificity,it has the potential to remove a wide range of drugs from Chinese materia medica(CMM),including conventional medicines and active compounds.Increasing evidence has confirmed the superior therapeutic effectiveness of CMM in treating a wide range of diseases worldwide,as well as in conjunction with western drugs.As a result,herbal medicine-drug compounds have prompted widespread concern,with the majority of these interactions involving transporters such as P-gp.This review systematically summarizes the inhibition or induction of P-gp expression/function by active CMM compounds and the underlying regulatory mechanisms.It will aid in improving understanding of the synergistic or inhibiting effects associated with transporter P-gp as well as rational safety concerns for using CMM,particularly in combination with drugs.展开更多
This article introduces various editions of Ben Cao Gang Mu(《本草纲目》Compendium of Materia Medica)and displays or collects in the Shanghai Museum of Traditional Chinese Medicine(TCM),along with many other works on ...This article introduces various editions of Ben Cao Gang Mu(《本草纲目》Compendium of Materia Medica)and displays or collects in the Shanghai Museum of Traditional Chinese Medicine(TCM),along with many other works on the study of Li Shizhen.Li Shizhen is not only a distinguished physician and pharmacist in the Ming dynasty of China but also a great scientist in human history.The most prominent contribution Li had made was sorting and developing the traditional Chinese herbal medicine,with the compilation of Ben Cao Gang Mu(《本草纲目》Compendium of Materia Medica),which represented the highest level of pharmaceutical development of TCM from a new starting line.展开更多
文摘The earliest Ben Cao Jing(Classics of Materia Medica;25 C.E.–220 C.E.)appeared during the reign of the Han Dynasty(202 B.C.E.–220 C.E.);their origins are traceable to the religious group called Fang Xian Dao.In addition to their use as a medical reference,the Ben Cao Jing works were also used for religious purposes.Tao Hongjing(456 C.E.–536 C.E.),a famous doctor and Daoist(one member of the Chinese local religion,Daoism)of the Liang Dynasty(502 C.E.–557 C.E.),compiled the Ben Cao Jing Ji Zhu(Variorum of Classics of Materia Medica;456 C.E.–536 C.E.)based on the Shen Nong Ben Cao Jing(Shennong’s Classic of Materia Medica;25 C.E.–220 C.E.).During the compilation of this book,Tao made a radical medical revision to the Shen Nong Ben Cao Jing,by reducing its religious contents while complementing its medical contents.After such revisions,the ancient Ben Cao Jing was transformed from a religious manual into an herbal pharmacopoeia.
基金This study was financed by the grant from the Third National Level Premier Open Course Resources Program for Undergraduates by the Ministry of Education of China(No.2013-94).
文摘Bencao Tujing(Illustrated Classic of Materia Medica)is a brilliant and monumental compendium of materia medica by Su Song,which was published in 1061 and gathered ancestral knowledge from the Song dynasty as a legacy for posterity.The compendium emphasized the clinical applications of medicinal materials collected nationwide,which used illustrated atlases as references.The descriptions for each medicinal material subsumed the prescriptions containing it and were supplemented with relevant medical cases.Medical prescriptions predating the Song dynasty were included,which enhanced the clinical usefulness of the pharmacopoeia.The ancestral knowledge of materia medica was extensively merged with natural history throughout the compendium,which also made extensive reference to more than 200 Chinese classics,local gazetteers,and published works from the social and natural sciences.The inclusion of natural history and literature works changed the convention used in earlier pharmacopoeias to present medicines based solely on pharmacological analyses.The compendium also pioneered the inclusion of natural history in pharmacopoeia.Bencao Tujing helped establish China’s leading position in the field of materia medica.Su Song’s meticulous nature,truth-seeking attitude,and adherence to scientific thinking are truly worthy of emulation and promotion.
文摘This paper tests the hypothesis that the commentary trend of the Shen Nong Ben Cao Jing(Shen Nong’s Classic of the Materia Medica)arises alongside the fashionable philology of the time,or the aversion against the Jin-Yuan medical philosophy.After surveying 12 major commentaries,it is concluded that the situation is more complicated than a simple assertion.The seemingly opposite philosophy and philology approaches have been used eclectically to innovate the understanding of ancient traditional Chinese medicine texts.
文摘The Silk Road stretched over land and across seas connecting Europe,Africa,and Asia.The trade of medicine along these routes has had profound impacts on the populations and traditions they have come into contact with.Chinese Medicine is no exception as it has taken numerous nonnative products and incorporated them into the unique philosophical construct of systematic correspondences that govern its practice.By looking at the four categories of primary source materials and studying the history of medical exchange along the Silk Road,we can determine how and where this information is used in Chinese Medicine.The Materia Medica(ben cao本草)texts are the first source of information for this study that will explore multiple sources to better understand the development of Chinese Medicine in relation to the rest of the world.
文摘The search for possible effective local therapeutic agents led to the discovery of a plant that was later known as Fungus Melitensis.This parasitic flowering plant was initially believed to grow only on a small islet off Gozo known variably as General's or Fungus Rock.It is now known to be more widely distributed with a range extending from the Canary Islands to China.First mentioned in 1647 by the Maltese historian Gian Francesco Abela,the plant was later described and illustrated in 1674 by the Palermo botanist Paolo Boccone,while a detailed clinical treatise was prepared in 1689 by the Maltese physician Gio Francesco Bonamico.Based on the principles of the“doctrine of signatures,”the plant was considered useful by virtue of its color in conditions involving bleeding,while on the basis of the phallic appearance,it was considered efficacious for venereal disease.The medicinal properties of the plant became renowned throughout the European continent,increasing the demand for its collection and export.Measures were introduced to limit the collection to authorized individuals while physical access to the islet was made more difficult by cutting away the sloping parts of the islet.The plant lost its medicinal reputation during the early decades of the 19^th century and has now been relegated to the annals of medical history and folklore,though it is still designated a protected species.
文摘Ben Cao Gang Mu Ying Jiao Dui Zhao(《本草纲目影校对照》A Contrast between the Photocopy and Collation of Compendium ofMateria Medica),completed by Zhang Zhibin and Zheng Jinsheng,is the latest variorum on Ben Cao Gang Mu(《本草纲目》Compendium ofMateria Medica).Adopting five different Jinling editions as the master copy,the book carefully collates the complex contents on the original book by contrasting the photocopies with the supplement and correction,which makes it easy to use.What is more,full-form punctuation is used to mark the reference books and proper nouns,which is a big success feat in the research history of Ben Cao Gang Mu.
基金This study was supported by the National Natural Science Foundation of China(81430094)。
文摘The property theory of Chinese materia medica is one of the foundations of traditional Chinese medicine.The property of Chinese materia medica(PCMM)is a multi-dimensional expression of the effect of Chinese materia medica(CMM),and it is related to the clinical prescription that fully reflects the clinical effect evaluation of CMM in a holistic,systematic,and scientific way.This paper discusses the source,development,and application of the PCMM by considering not only the five dimensions that constitute the PCMM but also the recognition of the human body and disease as given in traditional Chinese medicine.This paper aims to provide theoretical guidance for the rational use and development of CMM.
文摘In ancient China, Daoist philosophers developed the concepts of qi(energy), Wu Xing(five elements), and yin(feminine, dark, negative) and yang(masculine, bright, positive) opposite forces between 200 and 600 BCE. Based on these philosophies, Zhen Jiu(acupuncture), Ben Cao(materia medica), and the practice of Qi Gong(energy optimization movements) evolved as the three interrelated therapeutic regimens of Chinese medicine(Note 1). Since the time of Zhang Qian, who discovered China's western regions in the 1st century BCE, Hai Yao(the exotic elements of materia medica from the maritime Silk Road countries), had been transmitted from the ancient land and maritime routes of the Silk Road to China in the past two millennia(Note 2). Since the late 17th century, the English East India Company, later called the British East India Company, introduced Yang Yao(opium) to the Manchu Qing Empire to balance a growing trade deficit for tea export from China to the British Empire. After the First Opium War ended in 1842, enterprising expatriate chemists and druggists in the treaty ports imported Xi Yao(modern medicines from the Western world) for sale to the merchant navy and the local market. From the second half of the 19th century onwards, both Hai Yao and Xi Yao have become a fully integrated part of modern China's armamentarium for the Chinese medicine and Western hospitals and retail pharmacy sectors. This paper articulates the journey of adoption of exotic elements of materia medica from the ancient land and sea routes of the Silk Road, including the western regions and the rest of the world in the past two millennia. Opium traders, ship surgeons, medical and pharmaceutical missionaries, enterprising traders, and policymakers together transformed Ben Cao into Xi Yao during the late Manchu Qing dynasty and the early Nationalist Era.
基金the Macao Science and Technology Development Fund(No.0067/2019/A2 and No.0075/2019/AMJ)from the Macao Special Administrative Region。
文摘P-glycoprotein(P-gp)is an important transmembrane ATP-binding cassette(ABC)drug efflux transporter expressed in various human tissues such as the intestines,liver,kidneys,and bloodbrain barrier.It limits the intracellular concentration of xenobiotics by pumping them out of the cells,affecting drug pharmacokinetics and therapeutic effects.With its broad substrate specificity,it has the potential to remove a wide range of drugs from Chinese materia medica(CMM),including conventional medicines and active compounds.Increasing evidence has confirmed the superior therapeutic effectiveness of CMM in treating a wide range of diseases worldwide,as well as in conjunction with western drugs.As a result,herbal medicine-drug compounds have prompted widespread concern,with the majority of these interactions involving transporters such as P-gp.This review systematically summarizes the inhibition or induction of P-gp expression/function by active CMM compounds and the underlying regulatory mechanisms.It will aid in improving understanding of the synergistic or inhibiting effects associated with transporter P-gp as well as rational safety concerns for using CMM,particularly in combination with drugs.
文摘This article introduces various editions of Ben Cao Gang Mu(《本草纲目》Compendium of Materia Medica)and displays or collects in the Shanghai Museum of Traditional Chinese Medicine(TCM),along with many other works on the study of Li Shizhen.Li Shizhen is not only a distinguished physician and pharmacist in the Ming dynasty of China but also a great scientist in human history.The most prominent contribution Li had made was sorting and developing the traditional Chinese herbal medicine,with the compilation of Ben Cao Gang Mu(《本草纲目》Compendium of Materia Medica),which represented the highest level of pharmaceutical development of TCM from a new starting line.