Prospective Comparative Study of Human Vas Occlusion with Chinese and Netherlandish Medical Materials

To find a new uas occlusive material and verily the efficacy of Zhao's traditional uas occlusion with medical polyurethane(MP),we used the aPProved medical silicone rubber (MSR) made in the Netherlands,for a prospective study in comparison with the contraceptive effect of these two materials.We adopted the standardized MPU uas occlusion method to 13subjects and the unified MSR uas occlusion method to 11 subjects. All subjects received semen analysis and related physical examination before the operation,and semen analysis and complication examination in the 3th, 6th and 12th months alter operation. Neither of groups had complication and notable uncomfortable symptoms following operation. The sperm disaPPearance rate in MPU group was 92.31%(12/13) while in MSR group, only one patient's sperm disaPPeared 3 moths after operation.During the other postoperative follow up periods all operated patients had spermatozoa allhough the sperm density decreased obviously and indicated partial vas occlusion.These results indicate that the MPU vas occlusion has a good sterilization elject,but the MSR has not.

Identification of Tibetan Medical Material Dracocephalum tanguticum Maxim.

[Objectives]To explore morphological identification,macroscopical identification,microscopic identification,thin layer chromatography(TLC)identification of Tibetan medical material Dracocephalum tanguticum Maxim.,and provide experimental data for its identification and application.[Methods]The Tibetan medical material was identified by means of original plant,characters,powder,paraffin section and thin layer chromatography(TLC).[Results]Tibetan medical material D.tanguticum Maxim.was obviously distinguished in character identification and microscopic identification,and the TLC method was simple and feasible.[Conclusions]The results will provide the source work foundation for the formulation of the quality standard of Sichuan Province(draft)for Tibetan medicinal material"D.tanguticum Maxim."and the development of pharmaceutical preparations for medical institutions.

Effects of Stretching Parameters on Morphological and Mechanical Properties of Polytetrafluoroethylene Filaments

Comprehensive performances of polytetrafluoroethylene(PTFE) flat filaments used as suture materials in medical field can be affected significantly by morphological and mechanical characteristics.Due to low tensile strength and non-uniform morphology,PTFE flat filaments cannot be applied widely as medical sutures.In order to solve flaws above,PTFE flat filaments with constant linear density,550 dtex,are manufactured and dependences of morphology,frictional features and mechanical behaviors on stretching ratio and temperature are also analyzed.The results indicate that PTFE flat filaments with high tensile strength(1 922.0 cN) and excellent apparent performance can be manufactured at optimal stretching ratio and temperature,18.0 and350 ℃,respectively.

Identification of Semen Celosiae and Cockscomb Flower Using Continuous Wavelet Transform with FTIR

Infrared spectra of semen celosiae and cockscomb flower can be obtained directly,quickly and accurately employing Fourier transform infrared spectroscopy (FTIR) with OMN1 sampler.Continuous wavelet transform (CWT) is employed to zoom in local region of infrared spectra of semen celosiae and cockscomb flower.Thus difference of infrared spectra between semen celosiae and cockscomb flower is greatly extruded.Identification rate is greatly improved. Daubechies wavelet is used as mother wavelet.CWT is implemented to the infrared spectra of semen celosiae and cockscomb flower.The difference between semen celosiae and cockscomb flower is observed at all scales in the continuous wavelet domain.An optimal scale is selected to identify semen celosiae and cockscomb flower.Experimental results show that it is effective to apply CWT on the basis of FTIR to identify traditional Chinese medicinal materials,which are the same general but different species.

RESORBABLE HIGH-STRENGTH ROD FOR FRACTURE INTERNAL FIXATION

Objective To find an ideal biomaterial for internal fixation. Methods Forty rabbits with fracture of the femur diaphysis (superiorcondyle) were treated by intramedullary nailing of femur with composites rod of resorbable DL-polylactic acid (PDLLA)-calcium metaphosphate (CMP), while steinmann's pin as control. The fracture healing, the material degradation and its mechanical properties were studied by X-ray films, macroscopic, microscopic and electron microscopic observations. Results No significant inflammatory reaction was found, and all the osteotomies were healed, while material was resorbed. Conclusion The PDLLA-CMP has excellent biocompatibility and mechanical properties, and it can be a promising implant material in orthopaedics surgery.

Recent advances in regenerative biomaterials

Nowadays,biomaterials have evolved from the inert supports or functional substitutes to the bioactive materials able to trigger or promote the regenerative potential of tissues.The interdisciplinary progress has broadened the definition of‘biomaterials’,and a typical new insight is the concept of tissue induction biomaterials.The term‘regenerative biomaterials’and thus the contents of this article are relevant to yet beyond tissue induction biomaterials.This review summarizes the recent progress of medical materials including metals,ceramics,hydrogels,other polymers and bio-derived materials.As the application aspects are concerned,this article introduces regenerative biomaterials for bone and cartilage regeneration,cardiovascular repair,3D bioprinting,wound healing and medical cosmetology.Cell-biomaterial interactions are highlighted.Since the global pandemic of coronavirus disease 2019,the review particularly mentions biomaterials for public health emergency.In the last section,perspectives are suggested:(i)creation of new materials is the source of innovation;(ii)modification of existing materials is an effective strategy for performance improvement;(iii)biomaterial degradation and tissue regeneration are required to be harmonious with each other;(iv)host responses can significantly influence the clinical outcomes;(v)the long-term outcomes should be paid more attention to;(vi)the noninvasive approaches for monitoring in vivo dynamic evolution are required to be developed;(vii)public health emergencies call for more research and development of biomaterials;and(viii)clinical translation needs to be pushed forward in a full-chain way.In the future,more new insights are expected to be shed into the brilliant field-regenerative biomaterials.

PDCA循环法在降低神经外科医用耗材中的应用

本文简述了PDCA循环法在医院神经外科降低医用耗材中的具体应用,采用柏拉图、鱼骨图分析,明确了影响神经外科医用耗材消耗高的因素及主要原因,结合6W法制定了降低卫生材料消耗率的改进措施。通过PDCA循环法实施前后一年的相关数据进行对比分析,结果表明:PDCA循环法在指导神经外科降低卫生材料消耗率和运营质量持续改进中有明显效果,卫生材料消耗呈现出明显可控下降趋势;百元医疗收入卫生材料消耗从2019年的46.92元下降到2020年的41.85元,下降幅度达到10.8%;出院病人均次费下降了10.9%。

Abnormal Blood Glucose Concentration on Degradation Behavior of AZ31 Magnesium Alloy

In order to evaluate the effect of blood glucose concentration on the reliability of AZ31 magnesium alloy medical implant,the corrosion of AZ31 alloy was studied in a simulated physiological saline solution.It is found that when the glucose concentration is in the normal range of ca.1g/L,the corrosion of AZ31 alloy can be inhibited However,when the glucose concentration becomes higher like that of diabetic patients,the degradation of AZ31 alloy is significantly accelerated.Therefore,for diabetic patients,the change in glucose concentration must be taken into consideration in order to ensure the reliability ofAZ31 medical implants.