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Measurement of Prolactin and Estradiol to Estimate Menses Return of Breastfeeding Mothers
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作者 Bi-huaJIN He-lianYU +3 位作者 Min-feiJIN Xue-liangDU Shu-rongYANG Jing-chuanWU 《Journal of Reproduction and Contraception》 CAS 2003年第2期111-117,共7页
Objective To determine whether the measurement of serum prolactin (PRL) and estradiol (E2) is effective and reliable to estimate the returning time of menses during breastfeedingMethods Serum PRL and E2 were measured ... Objective To determine whether the measurement of serum prolactin (PRL) and estradiol (E2) is effective and reliable to estimate the returning time of menses during breastfeedingMethods Serum PRL and E2 were measured in 703 breastfeeding mothers during the period of <2 , > 2, 3, 4, 5 and 6- 9 months postpartum. Radio-immunoassay (RIA) was used to measure the levels of PRL and E2. The cervical mucus, sexual behaviors and vagina bleeding were also monitored since 56 d after postpantum. Results (1) The average level of serum PRL and E2was 8. 16, 3. 66, 0. 69 in the fully breastfeeding, mixed-feeding and bottle-feeding groups respectively. It showed that 92. 55% mother returned menses -within 6 months of postpartum in the bottle-feeding group. (2) According to the results, the levels of serum Prolactin and Estradiol were related to the feeding ways, but not completely related to the duration of postpartum. (3) By using the ratio of PRL to E2to estimate the time of menses return among the breastfeeding mothers, we found that when the ratio became 0. 60, the subjects' menses would returen. .The sensitivity and the specificity of this method were 89. 85% and 90. 68% respectively.Conclusion The measurement of serum PRL and E2is a simple, effective and reliable method to estimate the return time of menses during breastfeeding period. If possible, it should be promoted for clinical use to prepare for their fertility return. 展开更多
关键词 serum Prolactin serum Estradiol menses return POSTPARTUM
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Laca ?Mense streita ?Premu 9 punktojn de la korpo kaj vi refresios post 10 minutoj
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《世界科学技术-中医药现代化》 1997年第2期30-31,共2页
关键词 os post 10 minutoj mense stre Premu 9 punktojn de la korpo kaj vi refresi Laca
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Discussing menstrual health in family medicine
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作者 Allison R Casola Alice Renaud Ashwini Kamath Mulki 《Family Medicine and Community Health》 2024年第2期23-26,共4页
MENSTRUAL HEALTH Menstrual health is a general biological marker for many cisgender women,transgender men and non-binary people.Despite more than half of the population being people who menstruate,stigma,lack of conve... MENSTRUAL HEALTH Menstrual health is a general biological marker for many cisgender women,transgender men and non-binary people.Despite more than half of the population being people who menstruate,stigma,lack of conversation and pressing social needs around menstrual health persists throughout medicine.1 Discussions around menstruation and menstrual management can be difficult for individuals,whether it is with friends or family,or in the healthcare setting.1 Patients who have never discussed menstruation with a clinician may not know what is healthy,assume that an abnormal experience is normal and may endure periods that negatively affect their life,career or well-being.2–5 Menstruation plays a vital role in overall well-being and contributes significantly to an individual’s quality of life.Given their scope of care,family medicine clinicians are poised to identify red-flag menstrual symptoms in their routine visits with patients,reducing time to diagnosis of menstrual disorders.We urge family medicine clinicians to have renewed conversations surrounding menstrual health with their patients.The purpose of this report is to supply a brief overview of the importance of menstrual communication in primary care and serve as a resource to enhance menstrual communication between patient and clinician,with the ultimate goal of decreasing menstrual stigma and promoting improved menstrual health and experiences for patients. 展开更多
关键词 ROUTINE MEN SPITE
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基于MENS-INS的智能手机室内定位系统 被引量:2
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作者 徐元坤 《测绘地理信息》 2015年第3期63-65,共3页
针对目前室内定位技术前期指纹数据采集工作量大、成本高、需部署特殊硬件的问题,提出了一种基于智能手机MENS_INS的室内定位系统。以Android系统为平台设计开发了一款手机应用,利用手机MENS中的陀螺仪、加速计和磁力计获取数据,采用IN... 针对目前室内定位技术前期指纹数据采集工作量大、成本高、需部署特殊硬件的问题,提出了一种基于智能手机MENS_INS的室内定位系统。以Android系统为平台设计开发了一款手机应用,利用手机MENS中的陀螺仪、加速计和磁力计获取数据,采用INS算法以及Kalman滤波,结合电子地图匹配算法,实现较长距离内定位精度控制在1~2 m,有助于室内定位技术的大规模推广。 展开更多
关键词 室内定位 智能手机 mens INS KALMAN滤波
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Men1通过调控FTO/ALKBH5表达和减少m6A甲基化而抑制小鼠肾纤维化
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作者 杨云巧 田倩婷 +8 位作者 潘婷 朱佳美 王子名 王旭艳 张拓 周宇霞 郭兵 陈腾祥 金帮明 《中国病理生理杂志》 CAS CSCD 北大核心 2024年第12期2193-2201,共9页
目的:探讨Men1基因在小鼠肾纤维化中的调控作用及分子机制。方法:使用C57BL/6小鼠建立单侧输尿管结扎(UUO)诱导的小鼠肾纤维化模型,随机分为sham组、UUO-3 d组、UUO-7 d组和UUO-14 d组,每组15只;构建条件性Men1敲除的小鼠模型,将Men1敲... 目的:探讨Men1基因在小鼠肾纤维化中的调控作用及分子机制。方法:使用C57BL/6小鼠建立单侧输尿管结扎(UUO)诱导的小鼠肾纤维化模型,随机分为sham组、UUO-3 d组、UUO-7 d组和UUO-14 d组,每组15只;构建条件性Men1敲除的小鼠模型,将Men1敲除的C57BL/6小鼠随机分为sham-Men1-WT、sham-Men1-CKO、UUO-Men1-WT和UUO-Men1-CKO组,每组8只。采用HE染色、Masson染色和天狼星红染色检测UUO诱导肾损伤及肾纤维化分析。构建MEN1敲除的人肾小管上皮HK-2细胞。通过RT-qPCR、Western blot、免疫组化染色和免疫荧光染色检测UUO小鼠肾组织和体外转化生长因子β(TGF-β;10μg/L)处理的HK-2细胞中MEN1、纤维化标志物(α-平滑肌肌动蛋白、Ⅲ型胶原和纤连蛋白1)、m^(6)A相关蛋白[甲基转移酶样蛋白3(METTL3)、METTL14、YTH结构域家族蛋白2(YTHDF2)、AlkB同源蛋白5(ALKBH5)和脂肪质量及肥胖相关蛋白(FTO)]的mRNA和蛋白表达;斑点印迹(dot blot)实验检测小鼠肾组织和HK-2细胞中m^(6)A甲基化水平。结果:Men1的表达随着肾纤维化加剧逐渐降低(P<0.01);Men1抑制肾组织中纤维化标志物的表达,Men1敲除增加UUO和TGF-β诱导的纤维化胶原的累积(P<0.01);Men1敲除小鼠肾组织和HK-2细胞中FTO和ALKBH5的表达下调(P<0.01),m^(6)A甲基化修饰水平升高(P<0.01);过表达FTO显著降低Men1缺失引起的m^(6)A修饰累积和肾纤维化(P<0.01)。结论:Men1基因缺失促进小鼠肾纤维化;Men1通过调控FTO/ALKBH5的表达降低m^(6)A修饰,从而抑制小鼠肾纤维化。 展开更多
关键词 MEN1基因 肾纤维化 单侧输尿管结扎 m6A RNA甲基化 FTO/ALKBH5
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MEN1在消化系统肿瘤中的研究进展
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作者 凡浩然(综述) 王震(审校) 《安徽医科大学学报》 CAS 北大核心 2024年第4期726-736,共11页
多发性内分泌腺肿瘤型1(MEN1)基因通过编码Menin调节细胞增殖和凋亡等过程,并且参与多个信号通路的调节,包括Wnt/β-catenin、Notch、Hedgehog/Dnmt1、Hippo等信号通路,这些都与肿瘤的发生、发展密切相关。因此,MEN1的突变或功能缺陷可... 多发性内分泌腺肿瘤型1(MEN1)基因通过编码Menin调节细胞增殖和凋亡等过程,并且参与多个信号通路的调节,包括Wnt/β-catenin、Notch、Hedgehog/Dnmt1、Hippo等信号通路,这些都与肿瘤的发生、发展密切相关。因此,MEN1的突变或功能缺陷可能导致肿瘤发生的风险增加。以往关于MEN1的研究主要集中于神经内分泌肿瘤,MEN1在神经内分泌肿瘤中作为抑癌基因发挥作用,其缺失突变引起的基因功能丧失,参与了神经内分泌肿瘤的发生发展。但近年研究表明,MEN1在不同的肿瘤中发挥不同的作用,如在胃癌中通过抑制IQ基元GTP酶激活蛋白1(IQGAP1)表现为抑癌基因,在肝癌中则通过甲基化相关途径表现为癌基因,在结直肠癌中通过自噬相关机制也表现为癌基因;而在食管癌、胰腺癌中MEN1的作用尚存在争议。现就近年来MEN1在消化系统肿瘤中的研究进展做一综述。 展开更多
关键词 MEN1 MENIN 基因突变 促癌基因 抑癌基因 消化系统肿瘤 组蛋白修饰 生物信息分析
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以合并纵隔肿瘤为主的多发性内分泌腺瘤病1型:病例报道与文献回顾
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作者 王卢凤 宋向欣 郭艳英 《新疆医学》 2024年第5期617-619,共3页
多发性内分泌腺瘤病是一组以多个不同的内分泌腺在同一个体先后或同时发生、以功能亢进为主要表现的常染色体显性遗传性疾病,分为多发性内分泌腺瘤病1型(MEN1)和多发性内分泌腺瘤病2型(MEN2),其中MEN1发生的重要原因是MEN1基因突变,导... 多发性内分泌腺瘤病是一组以多个不同的内分泌腺在同一个体先后或同时发生、以功能亢进为主要表现的常染色体显性遗传性疾病,分为多发性内分泌腺瘤病1型(MEN1)和多发性内分泌腺瘤病2型(MEN2),其中MEN1发生的重要原因是MEN1基因突变,导致肿瘤细胞11号染色体不同程度的杂合缺失,menin蛋白消失,临床主要表现为甲状旁腺腺瘤、胃肠胰腺内分泌肿瘤和垂体前叶瘤。MEN2又分为MEN2A和MEN2B,主要原因与原癌基因RET突变有关,临床表现为甲状腺髓样癌、嗜铬细胞瘤、甲状旁腺增生和黏膜神经纤维瘤。 展开更多
关键词 甲状旁腺腺瘤 神经纤维瘤 甲状旁腺增生 纵隔肿瘤 MEN1基因 甲状腺髓样癌 胰腺内分泌肿瘤 病例报道
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MEN1基因在前列腺癌中生物学功能的研究进展
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作者 石庆 王子琦 罗亚坤 《现代肿瘤医学》 CAS 2024年第17期3379-3384,共6页
近二十年来,我国前列腺癌的发病率逐年攀升,已经成为泌尿外科三大恶性肿瘤中最常见的一种。当下我国前列腺癌患者中,初诊即晚期的比例相比于欧美日等发达国家仍然较高,且有超过70%的晚期前列腺癌病患发生转移,若出现远处转移,其患者生... 近二十年来,我国前列腺癌的发病率逐年攀升,已经成为泌尿外科三大恶性肿瘤中最常见的一种。当下我国前列腺癌患者中,初诊即晚期的比例相比于欧美日等发达国家仍然较高,且有超过70%的晚期前列腺癌病患发生转移,若出现远处转移,其患者生存率仅为30%。因此,进一步寻找新的诊疗分子靶点就具有更加重要的现实意义和理论价值。研究证实多发性内分泌肿瘤1型(MEN1)基因编码的menin蛋白参与前列腺癌的发生发展,同时menin是前列腺治疗潜在的新靶点。该文将对MEN1基因结构及menin在前列腺癌中的生物学功能进行概述,重点探讨menin调控前列腺癌细胞增殖、迁移与侵袭的分子机理。以期为MEN1基因及menin蛋白在前列腺癌中的深入研究提供参考。 展开更多
关键词 前列腺癌 MEN1基因 分子机制 治疗策略
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MEN1基因阴性的多发性内分泌腺瘤1型合并2型糖尿病1例病例报道
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作者 牟芝群 张凌 +4 位作者 章莹 李思成 廖鑫 张旋 李明泽 《贵州医药》 CAS 2024年第11期1796-1799,共4页
多发性内分泌腺瘤病(MEN)是一组遗传性多种内分泌器官发生肿瘤综合征的总称,是指一个人同时或先后出现两个或两个以上的内分泌腺增生或肿瘤病变,可合并功能亢进[1]。多发性内分泌腺瘤1型(MEN1)是多发性内分泌腺瘤病的一种类型,是一种罕... 多发性内分泌腺瘤病(MEN)是一组遗传性多种内分泌器官发生肿瘤综合征的总称,是指一个人同时或先后出现两个或两个以上的内分泌腺增生或肿瘤病变,可合并功能亢进[1]。多发性内分泌腺瘤1型(MEN1)是多发性内分泌腺瘤病的一种类型,是一种罕见的常染色体显性遗传综合征,又称为Weber综合征,以甲状旁腺肿瘤、胃肠胰腺神经内分泌肿瘤和垂体前叶肿瘤为特征[2]。MEN1也可累及肾上腺皮质和其他组织(如甲状腺、支气管、胸腺、脂肪等)[3]。MEN1临床上比较罕见,尤其是症状、体征不典型者,更容易漏诊、误诊。本科近期收治MEN1阴性的多发性内分泌腺瘤1型合并2型糖尿病1例,现报告如下,以提高临床医师对本病的认识。 展开更多
关键词 多发性内分泌腺瘤病1型 MEN1 MEN1基因阴性 2型糖尿病
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Epidemiological Profile of Men Who Have Sex with Men: First Data about Male Sex Workers in Central African Republic (CAR)
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作者 Hermione Dahlia Mossoro-Kpinde Balekouzou Augustin +1 位作者 Paola Julienne Demba Henri Saint Calvaire Diemer 《Advances in Sexual Medicine》 2024年第1期1-11,共11页
Objectives: Sex work is not well documented among African men. The aim of this study was to describe the epidemiological profile of men who have sex with men (MSM) and eventually to determine the proportion of sex wor... Objectives: Sex work is not well documented among African men. The aim of this study was to describe the epidemiological profile of men who have sex with men (MSM) and eventually to determine the proportion of sex workers (SW) among them, as well as the proportion of MSM who have been victims of gender-based violence (GBV). Material and Methods: A cross-sectional study coordinated by the Direction de la Médecine du Travail was carried out at the headquarters of the association ALTERNATIVES in Bangui Bangui from July 1 to October 31, 2021. Consenting MSM present during the study period were systematically included. Sociodemographic variables, those relating to the future vision of the activity and to GBV were collected and analyzed using Epi-Info version 7 software. Results: Forty MSM with an average age of 23 years and mainly secondary education (75.0%) were included. The vast majority of MSM were unemployed (85.0%). 45.0% had been victims of GBV and wanted to stop working as an MSM (47.5%), and almost 2/3 (65.0%) would accept another income-generating activity in exchange for the MSM. Violence was sexual (32.5%), economic (22.5%), physical (20.0%), verbal (12.5%) and psychological (12.5%). Conclusion: The MSM were mainly young, poorly educated, unemployed, and almost half were victims of GBV. The desire to change MSM activity to another income-generating activity alongside that of MSM shows that many of them are SW, workers in the informal sector. This must be taken into account in prevention activities, even if the data needs to be confirmed on a much larger sample. 展开更多
关键词 Men Who Have Sex with Men Sex Workers Gender-Based Violence Informal Sector Central Africa
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Awareness, Practice and Intention to Practice Testicular Self-Examination among Professional Working Males in Ghana
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作者 Ninon P. Amertil Cecilia Amponsem-Boateng +2 位作者 Elikem K. Ayitey Doris Grace Kpongboe Pamphil Igman 《Journal of Cancer Therapy》 2024年第10期331-345,共15页
Background: The aetiology of Testicular Cancer (TC) is still unknown to researchers but many of the associated risk factors have been identified. These include family history, age, racial origin, cryptorchidism, uroge... Background: The aetiology of Testicular Cancer (TC) is still unknown to researchers but many of the associated risk factors have been identified. These include family history, age, racial origin, cryptorchidism, urogenital malformations, testicular atrophy, and infertility. Given the lack of scientific data on the causes of the disease, it has been asserted in previous studies that the promotion of awareness and early detection are prerequisites to mitigating risks of metastasis as well as improving survival. This study is to assess the awareness, practice, and intention to practice testicular self-examination among professional working males in Accra. Methods: A quantitative cross-sectional design with a structured research instrument was used to collect data from respondants. The purposive and convenience sampling techniques were used to collect data from 300 men at Accra in Ghana. The study was conducted at two (2) Universities and a Senior High school at Accra in Ghana. The data was then analysed using descriptive statistics, logistic regression, multiple linear regression, and structural equation modeling. Results: From the study findings, 37% of male participants rated their knowledge of testicular self-examination and related symptoms as good, 28% of participants practised testicular self-examination monthly, while 65% of respondents expressed their intention to practice monthly testicular self-examination. The findings from logistic regression demonstrated that level of education, age, and marital status of participants had a significant influence on testicular self-examination. Additionally, the multiple linear regression results revealed knowledge and self-efficacy significantly predict testicular self-examination intention. The path coefficient results from the structural equation model are consistent with results from the regression models. Conclusion: This research is the first to investigate testicular self-examination among men in Ghana. The findings revealed awareness and practice of TSE are low among participants. Therefore, the research findings would improve the expertise of physicians and nurses in providing counsel, intervention, and support for patients at risk of testicular cancer. 展开更多
关键词 Testicular Cancer Testicular Self-Examination Awareness and Practice Health Promotion Men’s Health
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A Study of Pearl Buck’s Translation View of Cultural Symbiosis
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作者 HU Chun-xiao 《Sino-US English Teaching》 2024年第11期515-519,共5页
Based on the theory of cultural symbiosis put forward by Mr.Zhang Liwen,this paper summarizes the translation view of cultural symbiosis,and uses it to explain the relevant characteristics of the Noble laureate Pearl ... Based on the theory of cultural symbiosis put forward by Mr.Zhang Liwen,this paper summarizes the translation view of cultural symbiosis,and uses it to explain the relevant characteristics of the Noble laureate Pearl Buck’s English translation of All Men Are Brothers.This paper,through laying out Buck’s cultural harmony value full in her translated work,probes into the connotation,manifestation,and enlightenment of Pearl Buck’s idea of a harmonious symbiosis of Chinese and Western cultures. 展开更多
关键词 Pearl S.Buck All Men Are Brothers Chinese and Western cultures cultural symbiosis
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Urethroplasty among Elderly Men, Surgical Techniques and Outcomes
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作者 Kwaku Addai Arhin Appiah George Amoah +7 位作者 Patrick Opoku Manu Maison Roland Azorliade Kwaku Otu-Boateng Douglas Arthur Dominic Annor Mintah Joseph Yorke George Asafu Adjaye Frimpong Christian Kofi Gyasi-Sarpong 《Open Journal of Urology》 2024年第3期179-187,共9页
Introduction: Urethroplasty remains the gold standard for the management of urethral stricture. However, the treatment of stricture disease in the elderly tends to be less invasive due to the presumption that they mig... Introduction: Urethroplasty remains the gold standard for the management of urethral stricture. However, the treatment of stricture disease in the elderly tends to be less invasive due to the presumption that they might not be able to stand long hours of surgery and might have higher rates of recurrence due to poor wound healing from microangiopathy. We present our experience with the outcomes of urethroplasty among elderly men seen at the Komfo Anokye Teaching Hospital from January 2012 to December 2021. Methods: This was a retrospective review of data captured in the urology database on all patients 65 years and above who underwent urethroplasty at the hospital over the study period. Data was obtained on patients’ demographics, stricture characteristics, urethroplasty technique, and outcome. A successful outcome was defined as peak flow rate > 15 mls/s, a patent urethra on retrograde urethrogram, patient satisfaction with urine stream, or restoration of the normal stream of urine with only one attempt at urethral calibration or internal urethrotomy postoperatively. Data was analyzed using PASW Statistics for Windows, Version 18.0. Results: Overall, 43 urethroplasties were done over the study period in elderly men. The age range was 65 to 87 years. The commonest aetiology was catheterization (62.79%) followed by urethritis (32.56%). Stricture length ranged from 0.5 cm to 16 cm with a mean of 3.93 cm. Most patients (60.46%) had bulbar urethral strictures. The repair methods employed were anastomotic urethroplasty (62.80%), fasciocutaneous flap (FCF) ventral onlay (13.95%), buccal mucosa graft (BMG) ventral onlay urethroplasty (4.65%), and staged urethroplasty (4.65%). Three of the patients (6.98%) had a combination of anastomotic and tissue transfer urethroplasty. The overall success rate was 88.37%. Complications included three surgical site infections, two urethral diverticula and one glans dehiscence. Conclusion: Elderly men tolerate urethroplasty well and the procedure should not be denied solely based on age. 展开更多
关键词 Urethral Stricture Elderly Men URETHROPLASTY Surgical Techniques
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月经生育因素与女性乳腺癌关系的病例对照研究 被引量:16
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作者 李泓澜 高立峰 +2 位作者 杨工 项永兵 金凡 《肿瘤》 CAS CSCD 北大核心 2000年第2期88-92,共5页
目的 探讨生育因素与女性乳腺癌的联系性 ,并结合 10年前的研究 ,比较生育因素在上海市区妇女中的时间趋势变化 ,以期从一个侧面对逐年增高的女性乳腺癌发病情况作出可能的解释。方法 一项基于全人群的病例对照研究 ,收集到 44 8对 ,1... 目的 探讨生育因素与女性乳腺癌的联系性 ,并结合 10年前的研究 ,比较生育因素在上海市区妇女中的时间趋势变化 ,以期从一个侧面对逐年增高的女性乳腺癌发病情况作出可能的解释。方法 一项基于全人群的病例对照研究 ,收集到 44 8对 ,1∶ 1年龄配对。通过条件 L ogistic模型进行相对危险度及剂量 -反应效应估计。结果 在调整一些可能的混杂因素后 ,月经初潮年龄≤ 12岁者发生乳腺癌的危险较 >12岁者高 4倍 ,95 %CI=1.7~ 14.5。行经年数长(≥ 40年 )与较短组 (<30年 )比较 ,有增加患乳腺癌危险的趋势 ,但该联系未达到显著性水平 (OR=1.8,95 %CI=0 .8~ 4.1)。高产次妇女 (≥ 3次 )的乳腺癌危险较未经产妇降低 6 0 %,趋势检验 P<0 .0 1。未发现流产与女性乳腺癌相关联。进一步调整产次后 ,累积哺乳月数与乳腺癌危险呈显著负相关 ,累积哺乳时间超过一年的与未哺乳者比较 OR=0 .5 ,95 %CI=0 .3~ 0 .8。口服避孕药与乳腺癌的相关不密切。结论 生育因素是一类影响女性乳腺癌的主要因素。与以往研究结果比较 ,该人群中的初潮年龄有提早趋势 ,而生产次数、累积哺乳时间则显著减少 。 展开更多
关键词 乳腺癌 月经 生育 病例对照研究
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青少年痛经及相关因素分析 被引量:12
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作者 梁红玲 吴美琼 +2 位作者 伍洁莹 李卓珍 范利军 《中国妇幼保健》 CAS 北大核心 2005年第13期1591-1592,共2页
目的:调查痛经及其相关因素对青少年的影响,以便有效开展青春期保健教育。方法:采取整群抽样方法对江门市区以及乡镇中学部和大专院校女生进行问卷调查,对有效样本782份采用SPS10.0数据统计分析。结果:痛经发生率为54.2%,初潮年龄、月... 目的:调查痛经及其相关因素对青少年的影响,以便有效开展青春期保健教育。方法:采取整群抽样方法对江门市区以及乡镇中学部和大专院校女生进行问卷调查,对有效样本782份采用SPS10.0数据统计分析。结果:痛经发生率为54.2%,初潮年龄、月经周期、经期暴饮暴食及抽烟喝酒与痛经无直接关系,P值>0.05。月经期参加不适宜运动、经期冷水淋浴、经期不良情绪、吃生冷食物与痛经有直接关系。经χ2检验,P值依次为χ2=13.350,P<0.001,χ2=4.054,P<0.05,χ2=28.935,P<0.001,χ2=4.356,P<0.005。结论:应加强青少年重视月经生理的宣传教育,消除她们的恐惧、焦虑及精神负担,加强经期卫生,避免剧烈运动、过度劳累和防止受寒,做好经期卫生保健,是预防妇女疾病的重要环节之一,有利于青少年健康成长。 展开更多
关键词 痛经 青春期 经期保健
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质量交换网络综合 被引量:7
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作者 薛东峰 陈理 +1 位作者 袁一 姚平经 《现代化工》 EI CAS CSCD 北大核心 2001年第6期16-19,21,共5页
质量交换网络 (MEN)综合是过程系统工程的新兴分支方向。本文介绍了质量交换网络综合的研究内容和研究进展 ,对两类研究方法即目标设定法和数学规划法做了简要介绍 ,对伴随反应的质量交换网络、热致分离网络、废物截断分配网络等3种重要... 质量交换网络 (MEN)综合是过程系统工程的新兴分支方向。本文介绍了质量交换网络综合的研究内容和研究进展 ,对两类研究方法即目标设定法和数学规划法做了简要介绍 ,对伴随反应的质量交换网络、热致分离网络、废物截断分配网络等3种重要的MEN进行了详细阐述。指出今后应加强质量集成在预防污染和清洁生产中的应用研究 ,进行能量集成和质量集成相结合的全面的过程集成研究 。 展开更多
关键词 质量交换网络 质量集成 综合 清洁生产 MEN
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近20年乳腺癌发病的常见危险因素变化分析 被引量:11
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作者 刘山 黄晓蓉 易瑛 《华西医学》 CAS 2007年第4期729-730,共2页
目的:了解近20年乳腺癌发病的常见危险因素变化及探讨相应的预防措施。方法:回顾性分析自1987年~2006年20年来所收治的1258例乳腺癌病人的临床资料,经χ2检验比较各组有无差异。结果:①乳腺癌病人高发年龄仍在40~49岁之间,<40岁和... 目的:了解近20年乳腺癌发病的常见危险因素变化及探讨相应的预防措施。方法:回顾性分析自1987年~2006年20年来所收治的1258例乳腺癌病人的临床资料,经χ2检验比较各组有无差异。结果:①乳腺癌病人高发年龄仍在40~49岁之间,<40岁和≥50岁在各组中所占的比例近20年无明显变化。②近20年来月经初潮年龄≤12岁的乳腺癌病人明显增多,而产次和累计哺乳月数却明显减少。③早期乳腺癌(I期)所占比重增大。结论:月经初潮年龄提前而产次和累计哺乳月数减少可以部分解释近年来逐年增高的乳腺癌发病率。早期乳癌所占比重大,为手术方式从传统根治术到改良根治术及保留乳腺的局部切除加放、化疗提供依据。 展开更多
关键词 乳腺癌 危险因素 月经 哺乳
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抗-β2糖蛋白1抗体在女性不孕症及先兆性流产中的检测及意义 被引量:9
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作者 李娜 荣扬 王珍光 《现代检验医学杂志》 CAS 2015年第2期42-45,共4页
目的:探讨抗-β2糖蛋白1抗体与女性不孕、先兆流产和月经紊乱之间的关系。方法选取2013年8月~2014年1月在海军总医院辅助医学生殖中心就诊的女性不孕症患者547例、先兆流产患者229例、妇科月经紊乱患者60例和正常孕龄女性31例。应用... 目的:探讨抗-β2糖蛋白1抗体与女性不孕、先兆流产和月经紊乱之间的关系。方法选取2013年8月~2014年1月在海军总医院辅助医学生殖中心就诊的女性不孕症患者547例、先兆流产患者229例、妇科月经紊乱患者60例和正常孕龄女性31例。应用酶联免疫吸附法(ELISA)对各组的抗-β2糖蛋白1抗体(aβ2GP1)进行检测分析,包括抗-β2糖蛋白1抗体-IgM(aβ2GP1-IgM)和抗-β2糖蛋白1抗体-IgG(aβ2GP1-IgG)。同时选取114例不孕不育及先兆流产患者,检测其经阿司匹林、强的松治疗前后的抗-β2糖蛋白1抗体(Ig-G/Ig-M)。结果健康组、女性不孕组、先兆流产组和月经紊乱组抗-β2糖蛋白1抗体-IgG 的阳性率分别是0%,0.36%,0.43%和1.6%;健康组、月经紊乱组、先兆流产组和女性不孕组抗-β2糖蛋白1抗体-IgM 的阳性率为3.2%,8.3%,19.21%和20.29%,女性不孕组、先兆流产组抗-β2糖蛋白1抗体-IgM抗体与对照组差异均具有统计学意义(χ^2=4.87~5.27,P 值均<0.05);女性不孕组经阿司匹林联合强的松治疗前后抗-β2糖蛋白1抗体-IgM(47.14±34.85 RU/ml 和31.14±27.64 RU/ml)和抗-β2糖蛋白1抗体-IgG(1.81±3.63 RU/ml 和1.14±1.99 RU/ml),差异具有统计学意义(P 值均<0.01),先兆流产组经阿司匹林联合强的松治疗前后抗-β2糖蛋白1抗体-IgM(37.75±31.20 RU/ml 和24.34±24.48 RU/ml)差异具有统计学意义(P 值均<0.01),抗-β2糖蛋白1抗体-IgG (1.45±1.76 RU/ml 和1.32±1.52 RU/ml)差异无统计学意义(P 值=0.718)。结论抗-β2糖蛋白1抗体-IgM 与女性不孕不育及先兆流产有密切相关性,是引起女性不孕及先兆流产的重要因素。 展开更多
关键词 抗-β2糖蛋白1抗体 不孕症 先兆流产 月经紊乱
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衡阳市女大学生月经状况调查分析 被引量:9
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作者 黄波 让蔚清 龙颖 《实用预防医学》 CAS 2004年第1期34-35,共2页
目的 了解女大学生月经生理状况 ,防治月经病。 方法 衡阳市两所大学的 2 80名女生 ,采用随机抽样问卷调查的方法进行统计分析。 结果 月经初潮年龄提前 ,女大学生中痛经发生率、痛经程度较高。 结论 大学生自身缺乏生理卫生知识 。
关键词 月经 大学生 调查 痛经
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455例女大学生月经经前紧张综合征的分析 被引量:11
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作者 朱宪 周军 李秀华 《首都医科大学学报》 CAS 2008年第6期784-787,共4页
目的了解女大学生经前期紧张综合征的影响因素,确立健康教育的重点。方法选择某大学1~3年级不同专业的体检女生460人进行问卷调查。调查内容为经前期症状及行经期间的一般症状。结果调查问卷460份问卷,有效455份,有效率为98.9%。61%以... 目的了解女大学生经前期紧张综合征的影响因素,确立健康教育的重点。方法选择某大学1~3年级不同专业的体检女生460人进行问卷调查。调查内容为经前期症状及行经期间的一般症状。结果调查问卷460份问卷,有效455份,有效率为98.9%。61%以上的女大学生有不同程度的经前期紧张综合征症状出现。女大学生月经周期发生改变和经前期紧张综合征加重,大多与情绪波动、环境变化、生活习惯改变、经期体育活动、学习紧张等因素有关,52%的女大学生对月经周期的改变及经前期紧张综合征加重有思想顾虑。结论痛经及经前期紧张综合征发生率较高;影响女生正常月经调节因素的顺位依次为环境因素、生物因素、气质特征及负性生活事件;不同专业、考试的心理压力以及体育运动对正常月经也有一定的影响。大学生的性健康教育是预防、治疗月经失调及经前期紧张综合征的有效处方。 展开更多
关键词 月经经前期紧张 综合征 性心理学
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