Dysfunctional attitudes,social support,negative life events,and depressive symptoms in Chinese adolescents:A moderated mediation model

BACKGROUND Depression is a prevalent psychological issue in adolescents that is significantly related to negative life events(NLEs)and dysfunctional attitudes.High levels of social support can significantly buffer NLEs’effect on depression.Currently,there is limited research on how social support moderates the relationship between NLEs,dysfunctional attitudes,and depression in adolescents in China.It is imperative to investigate this moderating effect to mitigate dysfunctional attitudes in adolescent undergoing depressive mood,ultimately enhancing their overall mental health.AIM To investigate the relationship and underlying mechanisms between specific dysfunctional attitudes,social support,and depression among Chinese adolescents.METHODS This is a cross-sectional study which selected five middle schools in Shandong Province for investigation in March 2022.Participants included 795 adolescents(49.87%male,mage=15.15,SD=1.84,age range=11-18 years old).All participants completed the Dysfunctional Attitude Scale,Adolescent Life Event Scale,Beck Depression Inventory,and Social Support Rating Scale.A moderated mediation model was conducted to examine the relationship between specific dysfunctional attitudes,social support,and depression.RESULTS Results indicated that NLEs affected depression through the mediating role of specific dysfunctional attitudes(autonomy attitudesβ=0.21;perfectionismβ=0.25).Moreover,social support was found to moderate the mediating effect between NLEs,specific dysfunctional attitudes,and depressive symptoms(autonomy attitudes b2=-0.08;perfectionism b2=-0.09).CONCLUSION Dysfunctional attitudes mediated and social support moderated the relationship between NLEs and depression.Social support can buffer depression symptoms among adolescents with autonomy attitudes and perfectionism.

Effect of Dendrobium nobile powder combined with conventional therapy on mild to moderate fatty liver

BACKGROUND Nonalcoholic fatty liver disease(NAFLD)encompasses a variety of liver conditions impacting individuals who consume minimal or no alcohol.Recently,traditional Chinese medicine has been gradually used to treat mild to moderate fatty liver,among which Dendrobium nobile Lindl.powder has been affirmed by many doctors and patients to be effective.However,there is limited research on combining this treatment with standard therapies for mild to moderate NAFLD.AIM To survey the effect of combining Dendrobium nobile Lindl.powder with standard treatment on liver function and lipid metabolism disorder in patients with mild to moderate NAFLD.METHODS Eighty patients with mild to moderate NAFLD participated in this retrospective study,classified into two groups:The observation group(n=40)and the control group(n=40).In November 2020 and November 2022,the study was conducted at People’s Hospital of Chongqing Liang Jiang New Area.The control group received standard treatment,while the observation group received Dendrobium nobile Lindl.powder based on the control group.The study compared differences in traditional Chinese medicine clinical syndrome scores,liver fibrosis treatment,liver function indicators,lipid levels,and serum inflammatory factor levels before and after treatment,and we calculated the incidence of adverse reactions for both groups.RESULTS The total effective rate was 97.50%in the observation group and 72.5%in the control group.After 8 weeks of treatment,the main and secondary symptom scores remarkably decreased,especially in the observation group(P<0.05),and there was a significant reduction in the serum levels of hyaluronic acid(HA),laminin(LN),human rocollagen III(PC III),and collagen type IV(CIV).The levels of HA,LN,PC III,and CIV were significantly lower in the observation group(P<0.05).After 8 weeks,both groups indicated remarkable improvements in liver function and blood lipid levels,with the observation group having even lower levels(P<0.05).Serum levels of interleukin-1β,tumor necrosis factor-α,and interleukin-8 also dropped significantly.The observation group had a lower rate of adverse reactions(5.00%)compared to the control group(22.50%).CONCLUSION Adding Dendrobium nobile Lindl.powder to standard treatment has been found to remarkably improve symptoms and reduce inflammation in patients with mild to moderate fatty liver disease.It also enhances hepatic function and lipid profile,ameliorates liver fibrosis indices,and lowers the risk of side effects.Consequently,this therapeutic protocol shows promise for clinical implementation and dissemination.

Parental Psychological Control and Internet Gaming Disorder Tendency:A Moderated Mediation Model of Core Self-Evaluation and Intentional Self-Regulation

Internet gaming disorder(IGD)among junior high school students is an increasingly prominent mental health concern.It is important to look for influences behind internet gaming disorder tendency(IGDT)in the junior high school student population.The present study aimed to reveal the explanatory mechanisms underlying the association between parental psychological control(PPC)and internet gaming disorder tendency among junior high school students by testing the mediating role of core self-evaluation(CSE)and the moderating role of intentional self-regulation(ISR).Participants in present study were 735 Chinese junior high school students who completed offline self-report questionnaires on parental psychological control,core self-evaluation,intentional self-regulation,and Internet gaming disorder tendency.Analyses were conducted via mediation and moderated mediation.The results showed that:(1)Parental psychological control was positively related to junior high school students’Internet gaming disorder tendency.Core self-evaluation,and intentional self-regulation were negatively related to junior high school students’Internet gaming disorder tendency,respectively.(2)Core self-evaluation partially mediated the relationship between parental psychological control and junior high school students’Internet gaming disorder tendency.(3)Intentional self-regulation moderated the association between parental psychological control and Internet gaming disorder tendency,as well as the relationships between parental psychological control and core self-evaluation and core self-evaluation and Internet gaming disorder tendency in the mediated model.Based on these findings,we believe that there is a need to weaken parental psychological control,strengthen junior high school students’core self-evaluation and intentional self-regulation,and to recognize the important role of parents as well as their children’s personal positive traits in the healthy development of junior high school students.

Analysis of Influencing Factors of Moderate to Severe Malnutrition in Elderly Patients with Lung Cancer during Chemotherapy

Objective:This study aims to identify the factors influencing moderate to severe malnutrition in elderly lung cancer patients undergoing chemotherapy and to provide a basis for developing clinical prevention and intervention strategies.Methods:The clinical data of 150 elderly lung cancer patients who received chemotherapy were retrospectively analyzed.Demographic data,clinical characteristics,laboratory indicators,treatment plans,and other relevant information were collected.Independent risk factors for moderate to severe malnutrition during chemotherapy were identified.Results:During chemotherapy,50 patients(33.33%)developed moderate to severe malnutrition.The BMI of patients with moderate to severe malnutrition was significantly lower than that of patients with no or mild malnutrition(21.20±1.60 vs.26.14±2.31,P<0.001),and the proportion of patients with stage IV tumors was significantly higher(60.00%vs.27.00%,P<0.001).Serum pre-albumin(pre-ALB)and hemoglobin(Hb)levels in patients with moderate to severe malnutrition were significantly lower than those in patients with no or mild malnutrition(152.67±30.41 g/L vs.252.47±51.24 g/L and 102.44±10.09 g/L vs.154.21±15.18 g/L,respectively,P<0.001 for all).Conclusion:Low BMI,decreased serum pre-ALB levels,and decreased serum Hb levels before chemotherapy are independent risk factors for moderate to severe malnutrition in elderly lung cancer patients during chemotherapy.Close clinical attention should be given to these patients,with early intervention measures such as nutritional support to reduce the incidence of malnutrition and improve patients’quality of life and prognosis.

Optimization of copper extraction for bioleaching of complex Cu-polymetallic concentrate by moderate thermophiles

Effects of initial pH, temperature, liquid volume, rotation speed, galvanic interaction （pyrite ratio） and pulp density on bioleaching of complex Cu-polymetallic concentrate were investigated. The results indicated that the copper extraction at pH 1.5 was 1.5 and 1.4 times that at pH 1.0 and pH 2.0 respectively. The copper extraction obtained at 45 ℃ was 1236.8%higher than that at 50 ℃. With the increase of rotation speed or the decrease of liquid volume, copper extraction was improved obviously. Copper extraction was improved gradually with the increase of pyrite ratio. However, when the ratio was higher than 20.0%, no further increase in copper extraction was observed. And the statistically significant interactive effects on copper extraction were found between temperature and pH, and temperature and pyrite ratio.

Surface species of chalcopyrite during bioleaching by moderately thermophilic bacteria

X-ray diffraction （XRD） and X-ray photoelectron spectroscopy （XPS） analyses were carried out to investigate the surface species and interfacial reactions during bioleaching of chalcopyrite by different strains of moderately thermophilic bacteria （45 °C）. Results show that monosulfide （CuS）, disulfide （S22？）, polysulfide （Sn2？）, elemental sulfur （S0） and sulfate （SO42？） are the main intermediate species on the surface of chalcopyrite during bioleaching byA. caldus,S. thermosulfidooxidans andL. ferriphilum. The low kinetics of dissolution of chalcopyrite inA. caldus can be mainly attributed to the incomplete dissolution of chalcopyrite and the passivation layer of polysulfide. Polysulfide and jarosite should be mainly responsible for the passivation of chalcopyrite in bioleaching byL. ferriphilumorS. thermosulfidooxidans. However, elemental sulfur should not be the main composition of passivation layer of chalcopyrite during bioleaching.

FINITE ELEMENT MODELING OF MODERATELY THICK COMPOSITE PLATE WITH PIEZOELECTRIC SENSORS AND ACTUATORS

A rectangular finite element for laminated plate with bonded and/or embedded piezoelectric sensors and actuators is developed based on the variational principle and the first order shear deformation theory. The element has four-node, 20-degrees-of-freedom with one potential degree of freedom for each piezoelectric layer to represent the piezoelectric behavior. The higher order derivation of deflection is obtained by using the normal rotation expressions to take the effects of transverse shear deformation into considerations. The finite element can accurately simulate the deformation of both thin and moderately thick plates. A Fortran program is written and a number of benchmark tests are exercised to verify its effectiveness. Results are compared well with the existing data. The unbalanced composite with piezoelectric layers is then analyzed by using the model. Results show that the changes of the ratio between the thickness of positive angle layers and the negative angle layers have an effect on the deformation of the structure under the same electric loading.

LARGE DEVIATIONS AND MODERATE DEVIATIONS FOR m-NEGATIVELY ASSOCIATED RANDOM VARIABLES

M-negatively associated random variables, which generalizes the classical one of negatively associated random variables and includes m-dependent sequences as its particular case, are introduced and studied. Large deviation principles and moderate deviation upper bounds for stationary m-negatively associated random variables are proved. Kolmogorov-type and Marcinkiewicz-type strong laws of large numbers as well as the three series theorem for m-negatively associated random variables are also given.

Comparative study on chalcopyrite bioleaching with assistance of different carbon materials by mixed moderate thermophiles

The catalysis of four carbon materials including artificial graphite(AG), carbon black(CB), activated carbon(AC) and carbon nanotube(CN) on chalcopyrite bioleaching by mixed moderate thermophiles was comparatively investigated. In AC and AG added bioleaching groups, low solution pH and suitable redox potential values, high total iron and ferric iron concentrations, and large number of adsorbed bacteria were obtained, resulting in high copper extractions. CB and CN inhibited the growth of bioleaching bacteria and led to the low bioleaching efficiency.X-ray diffraction analysis showed that jarosite and sulfur film were the main components of passivation layer with the addition of AG and AC,but did not hinder the dissolution of chalcopyrite. Microbial community structures of free and attached cells in AC and AG added groups changed dramatically compared with mixed moderate thermophiles. The sulfur-oxidizing bacteria of A. caldus S1 strain dominated the microbial community(93%-98%) at the end of bioleaching.The iron-oxidizing bacteria of L.ferriphilum YSK only accounted for low percentage(1%-2%).

MODERATE DEVIATIONS AND LARGEDE VIATIONS FOR A TEST OF SYMMETRY BASED ON KERNEL DENSITY ESTIMATOR

Let fn be a non-parametric kernel density estimator based on a kernel function K. and a sequence of independent and identically distributed random variables taking values in R. The goal of this article is to prove moderate deviations and large deviations for the statistic sup ｜fn（x） - fn（-x） ｜.

Effects of CO_2 Dilution on Methane Ignition in Moderate or Intense Low-oxygen Dilution(MILD) Combustion:A Numerical Study

Homogeneous mixtures of CH4/air under moderate or intense low-oxygen dilution（MILD） combustion conditions were numerically studied to clarify the fundamental effects of exhaust gas recirculation（EGR）,espe-cially CO2 in EGR gases,on ignition characteristics.Specifically,effects of CO2 addition on autoignition delay time were emphasized at temperature between 1200 K and 1600 K for a wide range of the lean-to-rich equivalence ratio（0.2~2）.The results showed that the ignition delay time increased with equivalence ratio or CO2 dilution ratio.Fur-thermore,ignition delay time was seen to be exponentially related with the reciprocal of initial temperature.Special concern was given to the chemical effects of CO2 on the ignition delay time.The enhancement of ignition delay time with CO2 addition can be mainly ascribed to the decrease of H,O and OH radicals.The predictions of tem-perature profiles and mole fractions of CO and CO2 were strongly related to the chemical effects of CO2.A single ignition time correlation was obtained in form of Arrhenius-type for the entire range of conditions as a function of temperature,CH4 mole fraction and O2 mole fraction.This correlation could successfully capture the complex be-haviors of ignition of CH4/air/CO2 mixture.The results can be applied to MILD combustion as ＂reference time＂,for example,to predict ignition delay time in turbulent reacting flow.

Bioleaching of chalcopyrite by mixed culture of moderately thermophilic microorganisms

A mixed culture of moderately thermophilic microorganisms was enriched from acid mine drainages(AMDs)samples collected from several sulphide mines in China,and the bioleaching of chalcopyrite was conducted both in shake flask and bioreactor.The results show that in the shake flask,the mixture can tolerate 50 g/L chalcopyrite after being acclimated to gradually increased concentrations of chalcopyrite.The copper extraction increases obviously in bioleaching of chalcopyrite with moderately thermophilic microorganisms supplemented with 0.4 g/L yeast extract at 180 r/min,74% copper can be extracted in the pulp of 50 g/L chalcopyrite after 20 d.Compared with copper extractions of mesophilic culture,unacclimated culture and acclimated culture without addition of yeast extract,that of accliniated culture with addition of yeast extract is increased by 53%,44% and 16%,respectively.In a completely stirred tank reactor,the mass fraction of copper and total iron extraction reach up to 81% and 56%,respectively.The results also indicate that it is necessary to add a large amount of acid to the pulp to extract copper from chalcopyrite effectively.

Application of Quality Control Circle Activity in Improving Effectiveness of Drug Intervention in Lung Cancer Patients with Moderate to Severe Pain

Objective:Lung cancer has the highest incidence and mortality of all malignant tumors in China.Cancer pain dramatically affects patients’comfort level,causing insomnia,anorexia,anxiety,fear,depression,and a decline in the quality of life(QOL).The literature suggests a shortage of adequate cancer pain management for 59.1% of patients in China.The quality control circle(QCC)activity reflects the people-oriented core idea of management.This study aimed to assess the efficacy of QCC in enhancing the effectiveness of drug interventions in lung cancer patients with moderate to severe pain.Methods:From January 2019 to July 2019,lung cancer patients with moderate to severe pain were treated with drugs.The total number of drug interventions was 3072.A QCC activity was performed following the ten steps of the plan-do-check-act(PDCA)model.The reasons for the poor effectiveness of drug intervention in lung cancer patients with moderate to severe pain were analyzed.Countermeasures were designed to improve the effectiveness of drug intervention,including setting up a pain college,writing a medication education manual,and formulating operational rules for the administration of narcotic drugs.The effectiveness of drug intervention in lung cancer patients with moderate to severe pain and activity ability scores of QCC members were analyzed statistically before and after QCC activity.The effectiveness of drug intervention was investigated and compared before and after establishing the QCC.Results:After establishing the PDCA model,the effectiveness of drug intervention for moderate to severe pain in lung cancer patients increased from 56.28% to 85.29%.Members had significant improvement in problem-solving ability,responsibility,communication,coordination,self-confidence,team cohesion,enthusiasm,QCC skills,and harmony.Conclusion:QCC activity can significantly improve the efficiency of drug intervention in lung cancer patients with moderate to severe pain and their quality of life.

Strength of massive to moderately jointed hard rock masses

The Hoek-Brown (HB) failure criterion and the geological strength index (GSI) were developed for the estimation of rock mass strength in jointed and blocky ground where rock mass failure is dominated by sliding along open joints and rotation of rock blocks. In massive, veined and moderately jointed rock in which rock blocks cannot form without failure of intact rock, the approach to obtain HB parameters must be modified. Typical situations when these modifications are required include the design of pillars, excavation and cavern stability, strainburst potential assessment, and tunnel support in deep underground conditions (around σ1/σci > 0.15, where σ1 is the major principal compressive stress and σci is the unconfined compressive strength of the homogeneous rock) in hard brittle rocks with GSI ≥ 65. In this article, the strength of massive to moderately jointed hard rock masses is investigated, and an approach is presented to estimate the rock mass strength envelope using laboratory data from uniaxial and triaxial compressive strength tests without reliance on the HB-GSI equations. The data from tests on specimens obtained from massive to moderately jointed heterogeneous (veined) rock masses are used to obtain the rock and rock mass strengths at confining stress ranges that are relevant for deep tunnelling and mining;and a methodology is presented for this purpose from laboratory data alone. By directly obtaining the equivalent HB rock mass strength envelope for massive to moderately jointed rock from laboratory tests, the HB-GSI rock mass strength estimation approach is complemented for conditions where the GSIequations are not applicable. Guidance is also provided on how to apply the proposed approach when laboratory test data are not or not yet available.

MODERATE DEVIATIONS FOR PARAMETER ESTIMATORS IN FRACTIONAL ORNSTEIN-UHLENBECK PROCESS

We study moderate deviations for estimators of the drift parameter of the fractional Ornstein-Uhlenbeck process. Two moderate deviation principles are obtained.

Evaluation of the use of sublevel open stoping in the mining of moderately dipping medium-thick orebodies

The flow of blasted ore during mining of moderately dipping medium-thick orebodies is a challenge.Selecting a suitable mining system for such ore bodies is difficult.This paper proposes a diamond layout sublevel open stoping system using fan blastholes with backfilling to mine such orebodies.To evaluate the performance of system the relationships between ore recovery and stope footwall dip angle,footwall surface roughness,drawpoint spacing and production blast ring burden were investigated.An ore recovery data set from 81 laboratory physical model experiments was established from combinations of the listed factors.Various modules in a back propagation neural network structure were compared,and an optimal network structure identified.An ore recovery backpropagation neural network(BPNN)forecast model was developed.Using the model and sensitivity analysis of the factors affecting the proposed open stope mining system,the significance of each factor on ore recovery was studied.The study results were applied to a case study at the Shandong Gold Group Jiaojia Gold Mine.The results showed that the application of a BPNN and sensitivity analysis models for ore recovery prediction in the proposed mining system and field experimental results confirm that the suggested mining method is feasible.

TEST AND CHARACTERIZATION FOR THE INCOMPRESSIBLE HYPERELASTIC PROPERTIES OF CONDITIONED RUBBERS UNDER MODERATE FINITE DEFORMATION

In this paper, the automated grid method is applied to test for the mechanical properties of conditioned rubbers under the moderate ?nite deformation (not exceeding 100%). More accurate stress-strain curves of conditioned rubber specimens under di?erent conditioned strains are obtained. Test results show di?erences between these curves. Based on an analysis of the classical constitutive models, a new modi?ed eight-chain model is proposed, which takes account of both the locking stretch of chains and the interaction e?ect in the network. Fitting test data shows that the modi?ed model well characterizes the incompressible hyperelastic mechanical behavior of conditioned rubbers under the moderate ?nite deformation as well as under the large deformation.

Moderate Resolution Imaging Camera (MoRIC) of China’s First Mars Mission Tianwen-1

China's first Mars exploration mission will carry out comprehensive global surveys of the planet from data collected by instruments carried in orbit and roving on the planet itself.Goals of the mission include detailed inspections and surveys of key areas on the surface of Mars.One of the main scientific payloads installed on the orbiter is the moderate resolution camera.Its mission is to image the surface of Mars sufficiently to produce a global remote sensing image map of the planet,and to explore and record changes to the topography of Mars,including major geological structures,and to advance research on topography and geomorphology in general.The moderate resolution camera uses a lightweight and compact integrated design;its primary components are an optical module,a focal plane module,a camera control module,a power and interface module,a camera support module,a thermal control module,and a reference module.Radiometric calibration,color calibration,and geometric calibration have been carried out to ensure that the camera can acquire sufficient accurate data to complete mission goals.This paper introduces the camera's detection mission,its system composition,and its working principle;it also describes the camera's ground calibration tests and their results,and provides a reference for processing the camera's scientific data and for future applications.

Experimental Performance of Moderate and High Temperature Heat Pump Charged with Refrigerant Mixture BY-3

Theoretical and experimental analysis of a new refrigerant mixture BY-3 was conducted based on a single-stage vapor compression refrigeration system. The water-water heat pump system used BY-3 to produce hot water when the low temperature was 20 ℃. The following results were obtained: the highest temperature at the condenser outlet reached about 85 ℃; when the difference between the water temperatures at the condenser outlet and the evaporator inlet was less than 40 ℃, the coefficient of performance (COP) was larger than 4; when the difference reached 55 ℃, the COP still kept 3; the discharge temperature of BY-3 was lower than 100 ℃, and the refrigerant vapor pressure kept lower than 1.8 MPa. When the water temperature at the condenser outlet reached over 85 ℃, nearly a 5 ℃ superheating temperature was maintained.

Moderate drought alleviates the damage to grain quality at high temperatures by improving the starch synthesis of inferior grains in japonica rice

In agricultural production,temperature and moisture are important factors affecting grain yield and quality.Although moderate drought at the grain-filling stage can effectively alleviate the damage caused by high temperature,the specific regulatory mechanism driving the effect of moderate drought at the high temperature on starch synthesis is still unclear.To explore the effects and mechanisms of high temperature and moderate drought on rice starch synthesis at the grainfilling stage,the activities of enzymes and expression levels of the genes involved in starch synthesis under four different treatments involving high temperature and/or water stress(CK,HT,WS,and HT+WS)were investigated in this study.The starch synthesis of a japonica inbred rice was measured under the four treatments during the grain filling.The results show that the effects of high temperature and moderate drought on grain filling mainly occur in the inferior grains of rice.Through the regulation of enzymes involved in starch synthesis and the expression levels of their main genes,the synthesis of rice starch can be affected.Therefore,the high temperature and moderate drought were antagonistic,and moderate drought can alleviate the damage to grain quality at a high temperature by improving the starch synthesis of inferior grains in japonica rice.This study provides a basis for stress-resistance cultivation and breeding strategies of rice with high temperature tolerance.