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A design and application of compound multi-functional sensor in wood-based panel processing
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作者 XU Kai-hong ZHOU Ding-guo 《Journal of Forestry Research》 SCIE CAS CSCD 2006年第4期319-322,共4页
A compound multi-functional sensor was designed by the study on the on-line testing technology of wood-based panels, and its properties of shape, functions, size, resistance to special environment were studied in deta... A compound multi-functional sensor was designed by the study on the on-line testing technology of wood-based panels, and its properties of shape, functions, size, resistance to special environment were studied in details. The operational principles of different sensors, technical flow of manufacturing, development of software systems of special functions, and the assessments of technical specification were also be introduced. This sensor adopted many new technologies, such as the applications of piezoresistant effect and heat sensitive effect can effectively measure the pressure and temperature, digital signal processing technology was used to extract and treat signals, and resist interference, encapsulation technology was used to keep the normal run of sensor under a harsh environment. Thus, the on-line compound multi-functional temperature/pressure sensor can be applied better to supervise the production of wood-based panels. All technical specifications of the compound multi-functional sensor were tested and the results met the requirements of the equipments. 展开更多
关键词 Wood-based panel processing multi-functional sensor Piezoresistant effect Heat sensitive effect
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Multi-functional photonic spin Hall effect sensor controlled by phase transition
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作者 程杰 李瑞昭 +3 位作者 程骋 张亚林 刘胜利 董鹏 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第7期336-342,共7页
Photonic spin Hall effect(PSHE), as a novel physical effect in light–matter interaction, provides an effective metrological method for characterizing the tiny variation in refractive index(RI). In this work, we propo... Photonic spin Hall effect(PSHE), as a novel physical effect in light–matter interaction, provides an effective metrological method for characterizing the tiny variation in refractive index(RI). In this work, we propose a multi-functional PSHE sensor based on VO_(2), a material that can reveal the phase transition behavior. By applying thermal control, the mutual transformation into different phase states of VO_(2) can be realized, which contributes to the flexible switching between multiple RI sensing tasks. When VO_(2) is insulating, the ultrasensitive detection of glucose concentrations in human blood is achieved. When VO_(2) is in a mixed phase, the structure can be designed to distinguish between the normal cells and cancer cells through no-label and real-time monitoring. When VO_(2) is metallic, the proposed PSHE sensor can act as an RI indicator for gas analytes. Compared with other multi-functional sensing devices with the complex structures, our design consists of only one analyte and two VO_(2) layers, which is very simple and elegant. Therefore, the proposed VO_(2)-based PSHE sensor has outstanding advantages such as small size, high sensitivity, no-label, and real-time detection, providing a new approach for investigating tunable multi-functional sensors. 展开更多
关键词 photonic spin Hall effect multi-functional sensors phase transition sensing performance
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Multi-functional optical fiber sensor system based on a dense wavelength division multiplexer
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作者 Yue-Xin Yin Zhifa Wu +4 位作者 Siwen Sun Liang Tian Xibin Wang Yuanda Wu Daming Zhang 《Chinese Physics B》 SCIE EI CAS CSCD 2019年第7期222-224,共3页
We propose a novel and efficient multi-functional optical fiber sensor system based on a dense wavelength division multiplexer(DWDM).This system consists of an optical fiber temperature sensor, an optical fiber strain... We propose a novel and efficient multi-functional optical fiber sensor system based on a dense wavelength division multiplexer(DWDM).This system consists of an optical fiber temperature sensor, an optical fiber strain sensor, and a 48-channel DWDM.This system can monitor temperature and strain changes at the same time.The ranges of these two sensors are from-20℃ to 100℃ and from-1000 με to 2000 με, respectively.The sensitivities of the temperature sensor and strain sensor are 0.03572 nm/℃ and 0.03808 nm/N, respectively.With the aid of a broadband source and spectrometer,different kinds and ranges of parameters in the environment can be monitored by using suitable sensors. 展开更多
关键词 DENSE wavelength DIVISION multiplexer(DWDM) planar LIGHTWAVE circuit multi-functional sensor optical fiber sensor system
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Smart Gas Sensors:Recent Developments and Future Prospective
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作者 Boyang Zong Shufang Wu +3 位作者 Yuehong Yang Qiuju Li Tian Tao Shun Mao 《Nano-Micro Letters》 SCIE EI CAS 2025年第3期55-86,共32页
Gas sensor is an indispensable part of modern society withwide applications in environmental monitoring,healthcare,food industry,public safety,etc.With the development of sensor technology,wireless communication,smart... Gas sensor is an indispensable part of modern society withwide applications in environmental monitoring,healthcare,food industry,public safety,etc.With the development of sensor technology,wireless communication,smart monitoring terminal,cloud storage/computing technology,and artificial intelligence,smart gas sensors represent the future of gassensing due to their merits of real-time multifunctional monitoring,earlywarning function,and intelligent and automated feature.Various electronicand optoelectronic gas sensors have been developed for high-performancesmart gas analysis.With the development of smart terminals and the maturityof integrated technology,flexible and wearable gas sensors play an increasingrole in gas analysis.This review highlights recent advances of smart gassensors in diverse applications.The structural components and fundamentalprinciples of electronic and optoelectronic gas sensors are described,andflexible and wearable gas sensor devices are highlighted.Moreover,sensorarray with artificial intelligence algorithms and smart gas sensors in“Internet of Things”paradigm are introduced.Finally,the challengesand perspectives of smart gas sensors are discussed regarding the future need of gas sensors for smart city and healthy living. 展开更多
关键词 Smart gas sensor Electronic sensor Optoelectronic sensor Flexible and wearable sensor Artificial intelligence
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Force and impulse multi-sensor based on flexible gate dielectric field effect transistor
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作者 Chao Tan Junling Lü +3 位作者 Chunchi Zhang Dong Liang Lei Yang Zegao Wang 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS 2025年第1期214-220,共7页
Nowadays,force sensors play an important role in industrial production,electronic information,medical health,and many other fields.Two-dimensional material-based filed effect transistor(2D-FET)sensors are competitive ... Nowadays,force sensors play an important role in industrial production,electronic information,medical health,and many other fields.Two-dimensional material-based filed effect transistor(2D-FET)sensors are competitive with nano-level size,lower power consumption,and accurate response.However,few of them has the capability of impulse detection which is a path function,expressing the cumulative effect of the force on the particle over a period of time.Herein we fabricated the flexible polymethyl methacrylate(PMMA)gate dielectric MoS_(2)-FET for force and impulse sensor application.We systematically investigated the responses of the sensor to constant force and varying forces,and achieved the conversion factors of the drain current signals(I_(ds))to the detected impulse(I).The applied force was detected and recorded by I_(ds)with a low power consumption of~30 nW.The sensitivity of the device can reach~8000%and the 4×1 sensor array is able to detect and locate the normal force applied on it.Moreover,there was almost no performance loss for the device as left in the air for two months. 展开更多
关键词 flexible gate dielectric transistor force sensor impulse sensor force sensor array
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An Artificial Intelligence‑Assisted Flexible and Wearable Mechanoluminescent Strain Sensor System
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作者 Yan Dong Wenzheng An +1 位作者 Zihu Wang Dongzhi Zhang 《Nano-Micro Letters》 SCIE EI CAS 2025年第3期217-231,共15页
The complex wiring,bulky data collection devices,and difficulty in fast and on-site data interpretation significantly limit the practical application of flexible strain sensors as wearable devices.To tackle these chal... The complex wiring,bulky data collection devices,and difficulty in fast and on-site data interpretation significantly limit the practical application of flexible strain sensors as wearable devices.To tackle these challenges,this work develops an artificial intelligenceassisted,wireless,flexible,and wearable mechanoluminescent strain sensor system(AIFWMLS)by integration of deep learning neural network-based color data processing system(CDPS)with a sandwich-structured flexible mechanoluminescent sensor(SFLC)film.The SFLC film shows remarkable and robust mechanoluminescent performance with a simple structure for easy fabrication.The CDPS system can rapidly and accurately extract and interpret the color of the SFLC film to strain values with auto-correction of errors caused by the varying color temperature,which significantly improves the accuracy of the predicted strain.A smart glove mechanoluminescent sensor system demonstrates the great potential of the AIFWMLS system in human gesture recognition.Moreover,the versatile SFLC film can also serve as a encryption device.The integration of deep learning neural network-based artificial intelligence and SFLC film provides a promising strategy to break the“color to strain value”bottleneck that hinders the practical application of flexible colorimetric strain sensors,which could promote the development of wearable and flexible strain sensors from laboratory research to consumer markets. 展开更多
关键词 Mechanoluminescent Strain sensor FLEXIBLE Deep learning WIRELESS
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Bioinspired Ultrasensitive Flexible Strain Sensors for Real‑Time Wireless Detection of Liquid Leakage
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作者 Weilong Zhou Yu Du +6 位作者 Yingying Chen Congyuan Zhang Xiaowei Ning Heng Xie Ting Wu Jinlian Hu Jinping Qu 《Nano-Micro Letters》 SCIE EI CAS 2025年第3期310-327,共18页
Liquid leakage of pipeline networks not only results in considerableresource wastage but also leads to environmental pollution and ecological imbalance.In response to this global issue, a bioinspired superhydrophobic ... Liquid leakage of pipeline networks not only results in considerableresource wastage but also leads to environmental pollution and ecological imbalance.In response to this global issue, a bioinspired superhydrophobic thermoplastic polyurethane/carbon nanotubes/graphene nanosheets flexible strain sensor (TCGS) hasbeen developed using a combination of micro-extrusion compression molding andsurface modification for real-time wireless detection of liquid leakage. The TCGSutilizes the synergistic effects of Archimedean spiral crack arrays and micropores,which are inspired by the remarkable sensory capabilities of scorpions. This designachieves a sensitivity of 218.13 at a strain of 2%, which is an increase of 4300%. Additionally, it demonstrates exceptional durability bywithstanding over 5000 usage cycles. The robust superhydrophobicity of the TCGS significantly enhances sensitivity and stability indetecting small-scale liquid leakage, enabling precise monitoring of liquid leakage across a wide range of sizes, velocities, and compositionswhile issuing prompt alerts. This provides critical early warnings for both industrial pipelines and potential liquid leakage scenariosin everyday life. The development and utilization of bioinspired ultrasensitive flexible strain sensors offer an innovative and effectivesolution for the early wireless detection of liquid leakage. 展开更多
关键词 Thermoplastic polyurethane BIOINSPIRED Cracks Liquid leakage Flexible strain sensor
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Flexible Strain Sensors with Ultra‑High Sensitivity and Wide Range Enabled by Crack‑Modulated Electrical Pathways
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作者 Yunzhao Bai Yunlei Zhou +6 位作者 Xuanyu Wu Mengfei Yin Liting Yin Shiyuan Qu Fan Zhang Kan Li YongAn Huang 《Nano-Micro Letters》 SCIE EI CAS 2025年第3期246-264,共19页
This study presents a breakthrough in flexible strain sensor technology with the development of an ultrahigh sensitivity and wide-range sensor,addressing the critical challenge of reconciling sensitivity with measurem... This study presents a breakthrough in flexible strain sensor technology with the development of an ultrahigh sensitivity and wide-range sensor,addressing the critical challenge of reconciling sensitivity with measurement range.Inspired by the structure of bamboo slips,we introduce a novel approach that utilises liquid metal to modulate the electrical pathways within a cracked platinum fabric electrode.The resulting sensor demonstrates a gauge factor greater than 108 and a strain measurement capability exceeding 100%.The integration of patterned liquid metal enables customisable tuning of the sensor’s response,while the porous fabric structure ensures superior comfort and air permeability for the wearer.Our design not only optimises the sensor’s performance but also enhances the electrical stability that is essential for practical applications.Through systematic investigation,we reveal the intrinsic mechanisms governing the sensor’s response,offering valuable insights for the design of wearable strain sensors.The sensor’s exceptional performance across a spectrum of applications,from micro-strain to large-strain detection,highlights its potential for a wide range of real-world uses,demonstrating a significant advancement in the field of flexible electronics. 展开更多
关键词 Flexible strain sensor FABRIC CRACK Response regulation Epidermal device
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Bioinspired Passive Tactile Sensors Enabled by Reversible Polarization of Conjugated Polymers
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作者 Feng He Sitong Chen +3 位作者 Ruili Zhou Hanyu Diao Yangyang Han Xiaodong Wu 《Nano-Micro Letters》 SCIE EI CAS 2025年第1期361-377,共17页
Tactile perception plays a vital role for the human body and is also highly desired for smart prosthesis and advanced robots.Compared to active sensing devices,passive piezoelectric and triboelectric tactile sensors c... Tactile perception plays a vital role for the human body and is also highly desired for smart prosthesis and advanced robots.Compared to active sensing devices,passive piezoelectric and triboelectric tactile sensors consume less power,but lack the capability to resolve static stimuli.Here,we address this issue by utilizing the unique polarization chemistry of conjugated polymers for the first time and propose a new type of bioinspired,passive,and bio-friendly tactile sensors for resolving both static and dynamic stimuli.Specifically,to emulate the polarization process of natural sensory cells,conjugated polymers(including poly(3,4-ethylenedioxythiophen e):poly(styrenesulfonate),polyaniline,or polypyrrole)are controllably polarized into two opposite states to create artificial potential differences.The controllable and reversible polarization process of the conjugated polymers is fully in situ characterized.Then,a micro-structured ionic electrolyte is employed to imitate the natural ion channels and to encode external touch stimulations into the variation in potential difference outputs.Compared with the currently existing tactile sensing devices,the developed tactile sensors feature distinct characteristics including fully organic composition,high sensitivity(up to 773 mV N^(−1)),ultralow power consumption(nW),as well as superior bio-friendliness.As demonstrations,both single point tactile perception(surface texture perception and material property perception)and two-dimensional tactile recognitions(shape or profile perception)with high accuracy are successfully realized using self-defined machine learning algorithms.This tactile sensing concept innovation based on the polarization chemistry of conjugated polymers opens up a new path to create robotic tactile sensors and prosthetic electronic skins. 展开更多
关键词 Passive tactile sensors Reversible polarization of conjugated polymers Tactile perception Machine learning algorithm Object recognition
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A smart finger patch with coupled magnetoelastic and resistive bending sensors
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作者 Ziyi Dai Mingrui Wang +4 位作者 Yu Wang Zechuan Yu Yan Li Weidong Qin Kai Qian 《Journal of Semiconductors》 2025年第1期194-203,共10页
In the era of Metaverse and virtual reality(VR)/augmented reality(AR),capturing finger motion and force interactions is crucial for immersive human-machine interfaces.This study introduces a flexible electronic skin f... In the era of Metaverse and virtual reality(VR)/augmented reality(AR),capturing finger motion and force interactions is crucial for immersive human-machine interfaces.This study introduces a flexible electronic skin for the index finger,addressing coupled perception of both state and process in dynamic tactile sensing.The device integrates resistive and giant magnetoelastic sensors,enabling detection of surface pressure and finger joint bending.This e-skin identifies three phases of finger action:bending state,dynamic normal force and tangential force(sweeping).The system comprises resistive carbon nanotubes(CNT)/polydimethylsiloxane(PDMS)films for bending sensing and magnetoelastic sensors(NdFeB particles,EcoFlex,and flexible coils)for pressure detection.The inward bending resistive sensor,based on self-assembled microstructures,exhibits directional specificity with a response time under 120 ms and bending sensitivity from 0°to 120°.The magnetoelastic sensors demonstrate specific responses to frequency and deformation magnitude,as well as sensitivity to surface roughness during sliding and material hardness.The system’s capability is demonstrated through tactile-based bread type and condition recognition,achieving 92%accuracy.This intelligent patch shows broad potential in enhancing interactions across various fields,from VR/AR interfaces and medical diagnostics to smart manufacturing and industrial automation. 展开更多
关键词 human machine interface flexible sensor wearable sensor giant magnetoelastic effect inward bending sensor
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Recent progress on artificial intelligence-enhanced multimodal sensors integrated devices and systems
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作者 Haihua Wang Mingjian Zhou +5 位作者 Xiaolong Jia Hualong Wei Zhenjie Hu Wei Li Qiumeng Chen Lei Wang 《Journal of Semiconductors》 2025年第1期179-192,共14页
Multimodal sensor fusion can make full use of the advantages of various sensors,make up for the shortcomings of a single sensor,achieve information verification or information security through information redundancy,a... Multimodal sensor fusion can make full use of the advantages of various sensors,make up for the shortcomings of a single sensor,achieve information verification or information security through information redundancy,and improve the reliability and safety of the system.Artificial intelligence(AI),referring to the simulation of human intelligence in machines that are programmed to think and learn like humans,represents a pivotal frontier in modern scientific research.With the continuous development and promotion of AI technology in Sensor 4.0 age,multimodal sensor fusion is becoming more and more intelligent and automated,and is expected to go further in the future.With this context,this review article takes a comprehensive look at the recent progress on AI-enhanced multimodal sensors and their integrated devices and systems.Based on the concept and principle of sensor technologies and AI algorithms,the theoretical underpinnings,technological breakthroughs,and pragmatic applications of AI-enhanced multimodal sensors in various fields such as robotics,healthcare,and environmental monitoring are highlighted.Through a comparative study of the dual/tri-modal sensors with and without using AI technologies(especially machine learning and deep learning),AI-enhanced multimodal sensors highlight the potential of AI to improve sensor performance,data processing,and decision-making capabilities.Furthermore,the review analyzes the challenges and opportunities afforded by AI-enhanced multimodal sensors,and offers a prospective outlook on the forthcoming advancements. 展开更多
关键词 sensor multimodal sensors machine learning deep learning intelligent system
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Advancements in implantable temperature sensors:Materials,mechanisms,and biological applications
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作者 Zhuofan Yang Hongcheng Song He Ding 《Journal of Semiconductors》 2025年第1期166-177,共12页
Implantable temperature sensors are revolutionizing physiological monitoring and playing a crucial role in diagnostics,therapeutics,and life sciences research.This review classifies the materials used in these sensors... Implantable temperature sensors are revolutionizing physiological monitoring and playing a crucial role in diagnostics,therapeutics,and life sciences research.This review classifies the materials used in these sensors into three categories:metal-based,inorganic semiconductor,and organic semiconductor materials.Metal-based materials are widely used in medical and industrial applications due to their linearity,stability,and reliability.Inorganic semiconductors provide rapid response times and high miniaturization potential,making them promising for biomedical and environmental monitoring.Organic semiconductors offer high sensitivity and ease of processing,enabling the development of flexible and stretchable sensors.This review analyzes recent studies for each material type,covering design principles,performance characteristics,and applications,highlighting key advantages and challenges regarding miniaturization,sensitivity,response time,and biocompatibility.Furthermore,critical performance parameters of implantable temperature sensors based on different material types are summarized,providing valuable references for future sensor design and optimization.The future development of implantable temperature sensors is discussed,focusing on improving biocompatibility,long-term stability,and multifunctional integration.These advancements are expected to expand the application potential of implantable sensors in telemedicine and dynamic physiological monitoring. 展开更多
关键词 IMPLANTABLE temperature sensors biological applications flexible electronics
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Recent progress in flexible sensors based on 2D materials
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作者 Xiang Li Guancheng Wu +1 位作者 Caofeng Pan Rongrong Bao 《Journal of Semiconductors》 2025年第1期130-142,共13页
With the rapid development of the internet of things(IoT)and wearable electronics,the role of flexible sensors is becoming increasingly irreplaceable,due to their ability to process and convert information acquisition... With the rapid development of the internet of things(IoT)and wearable electronics,the role of flexible sensors is becoming increasingly irreplaceable,due to their ability to process and convert information acquisition.Two-dimensional(2D)materials have been widely welcomed by researchers as sensitive layers,which broadens the range and application of flexible sensors due to the advantages of their large specific surface area,tunable energy bands,controllable thickness at the atomic level,stable mechanical properties,and excellent optoelectronic properties.This review focuses on five different types of 2D materials for monitoring pressure,humidity,sound,gas,and so on,to realize the recognition and conversion of human body and environmental signals.Meanwhile,the main problems and possible solutions of flexible sensors based on 2D materials as sensitive layers are summarized. 展开更多
关键词 2D materials flexible sensors layered structure solution method
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Design strategies and insights of flexible infrared optoelectronic sensors
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作者 Yegang Liang Wenhao Ran +1 位作者 Dan Kuang Zhuoran Wang 《Journal of Semiconductors》 2025年第1期21-56,共36页
Infrared optoelectronic sensing is the core of many critical applications such as night vision,health and medication,military,space exploration,etc.Further including mechanical flexibility as a new dimension enables n... Infrared optoelectronic sensing is the core of many critical applications such as night vision,health and medication,military,space exploration,etc.Further including mechanical flexibility as a new dimension enables novel features of adaptability and conformability,promising for developing next-generation optoelectronic sensory applications toward reduced size,weight,price,power consumption,and enhanced performance(SWaP^(3)).However,in this emerging research frontier,challenges persist in simultaneously achieving high infrared response and good mechanical deformability in devices and integrated systems.Therefore,we perform a comprehensive review of the design strategies and insights of flexible infrared optoelectronic sensors,including the fundamentals of infrared photodetectors,selection of materials and device architectures,fabrication techniques and design strategies,and the discussion of architectural and functional integration towards applications in wearable optoelectronics and advanced image sensing.Finally,this article offers insights into future directions to practically realize the ultra-high performance and smart sensors enabled by infrared-sensitive materials,covering challenges in materials development and device micro-/nanofabrication.Benchmarks for scaling these techniques across fabrication,performance,and integration are presented,alongside perspectives on potential applications in medication and health,biomimetic vision,and neuromorphic sensory systems,etc. 展开更多
关键词 FLEXIBLE infrared sensor infrared-sensitive materials device architectures fabrication techniques design strategies
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Design of Drilling and Riveting Multi-functional End Effector for CFRP and Aluminum Components in Robotic Aircraft Assembly 被引量:6
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作者 Zhang Lin Tian Wei +4 位作者 Li Dawei Hong Peng Li Zhenyu Zhou Weixue Liao Wenhe 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI CSCD 2018年第3期529-538,共10页
To fulfill the demands for higher quality,efficiency and flexibility in aviation industry,a multi-functional end effector is designed to automate the drilling and riveting processes in assembling carbon fiber reinforc... To fulfill the demands for higher quality,efficiency and flexibility in aviation industry,a multi-functional end effector is designed to automate the drilling and riveting processes in assembling carbon fiber reinforced polymer(CFRP)and aluminum components for a robotic aircraft assembly system.To meet the specific functional requirements for blind rivet installation on CFRP and aluminum materials,additional modules are incorporated on the end effector aside of the basic processing modules for drilling.And all of these processing modules allow for a onestep-drilling-countersinking process,hole inspection,automatic rivet feed,rivet geometry check,sealant application,rivet insertion and installation.Besides,to guarantee the better quality of the hole drilled and joints riveted,several online detection and adjustment measures are applied to this end effector,including the reference detection and perpendicular calibration,which could effectively ensure the positioning precision and perpendicular accuracy as demanded.Finally,the test result shows that this end effector is capable of producing each hole to a positioning precision within ±0.5 mm,aperpendicular accuracy within 0.3°,a diameter tolerance of H8,and a countersink depth tolerance of±0.01 mm.Moreover,it could drill and rivet up to three joints per minute,with acceptable shearing and tensile strength. 展开更多
关键词 robotic aircraft assembly CFRP and aluminum components automatic drilling and riveting multi-functional end effector online detection and adjustment
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Development of a novel multi-functional integrated bioconjugate effectively targeting K-Ras mutant pancreatic cancer 被引量:1
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作者 Yang-Yang Wang Liang Li +4 位作者 Xiu-Jun Liu Qing-Fang Miao Yi Li Meng-Ran Zhang Yong-Su Zhen 《Journal of Pharmaceutical Analysis》 SCIE CAS CSCD 2022年第2期232-242,共11页
Folate receptor(FR)overexpression occurs in a variety of cancers,including pancreatic cancer.In addition,enhanced macropinocytosis exists in K-Ras mutant pancreatic cancer.Furthermore,the occurrence of intensive desmo... Folate receptor(FR)overexpression occurs in a variety of cancers,including pancreatic cancer.In addition,enhanced macropinocytosis exists in K-Ras mutant pancreatic cancer.Furthermore,the occurrence of intensive desmoplasia causes a hypoxic microenvironment in pancreatic cancer.In this study,a novel FR-directed,macropinocytosis-enhanced,and highly cytotoxic bioconjugate folate(F)-human serum albumin(HSA)-apoprotein of lidamycin(LDP)-active enediyne(AE)derived from lidamycin was designed and prepared.F-HSA-LDP-AE consisted of four moieties:F,HSA,LDP,and AE.F-HSA-LDP presented high binding efficiency with the FR and pancreatic cancer cells.Its uptake in wild-type cells was more extensive than in K-Ras mutant-type cells.By in vivo optical imaging,F-HSA-LDP displayed prominent tumor-specific biodistribution in pancreatic cancer xenograft-bearing mice,showing clear and lasting tumor localization for 360 h.In the MTT assay,F-HSA-LDP-AE demonstrated potent cytotoxicity in three types of pancreatic cancer cell lines.It also induced apoptosis and caused G2/M cell cycle arrest.F-HSALDP-AE markedly suppressed the tumor growth of AsPc-1 pancreatic cancer xenografts in athymic mice.At well-tolerated doses of 0.5 and 1 mg/kg,(i.v.,twice),the inhibition rates were 91.2%and 94.8%,respectively(P<0.01).The results of this study indicate that the F-HSA-LDP multi-functional bioconjugate might be effective for treating K-Ras mutant pancreatic cancer. 展开更多
关键词 Pancreatic cancer Folate receptor multi-functional Macropinocytosis-enhanced BIOCONJUGATE K-RAS PEGYLATION
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Fiber-Loop Ringdown Multi-Function Sensors
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作者 Ke Zhao Bokai Yi Zefeng Wang 《Journal of Applied Mathematics and Physics》 2014年第12期1118-1122,共5页
We demonstrate a fiber-loop ring down multi-function sensors system, which can be used to measure refractive index and curvature simultaneously. Good agreement has been found between theoretical analyses and experimen... We demonstrate a fiber-loop ring down multi-function sensors system, which can be used to measure refractive index and curvature simultaneously. Good agreement has been found between theoretical analyses and experimental results. It has great potential for sensor applications. 展开更多
关键词 Fiber-Loop RINGDOWN multi-function sensorS Refractive INDEX sensorS CURVATURE sensorS
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Collaborative positioning for swarms:A brief survey of vision,LiDAR and wireless sensors based methods 被引量:1
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作者 Zeyu Li Changhui Jiang +3 位作者 Xiaobo Gu Ying Xu Feng zhou Jianhui Cui 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第3期475-493,共19页
As positioning sensors,edge computation power,and communication technologies continue to develop,a moving agent can now sense its surroundings and communicate with other agents.By receiving spatial information from bo... As positioning sensors,edge computation power,and communication technologies continue to develop,a moving agent can now sense its surroundings and communicate with other agents.By receiving spatial information from both its environment and other agents,an agent can use various methods and sensor types to localize itself.With its high flexibility and robustness,collaborative positioning has become a widely used method in both military and civilian applications.This paper introduces the basic fundamental concepts and applications of collaborative positioning,and reviews recent progress in the field based on camera,LiDAR(Light Detection and Ranging),wireless sensor,and their integration.The paper compares the current methods with respect to their sensor type,summarizes their main paradigms,and analyzes their evaluation experiments.Finally,the paper discusses the main challenges and open issues that require further research. 展开更多
关键词 Collaborative positioning VISION LIDAR Wireless sensors sensor fusion
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MXene-Based Elastomer Mimetic StretchableSensors: Design, Properties, and Applications 被引量:3
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作者 Poushali Das Parham Khoshbakht Marvi +5 位作者 Sayan Ganguly Xiaowu(Shirley)Tang Bo Wang Seshasai Srinivasan Amin Reza Rajabzadeh Andreas Rosenkranz 《Nano-Micro Letters》 SCIE EI CAS CSCD 2024年第7期295-342,共48页
Flexible sensors based on MXene-polymer composites are highly prospective for next-generation wearable electronics used in human-machine interfaces.One of the motivating factors behind the progress of flexible sensors... Flexible sensors based on MXene-polymer composites are highly prospective for next-generation wearable electronics used in human-machine interfaces.One of the motivating factors behind the progress of flexible sensors is the steady arrival of new conductive materials.MXenes,a new family of 2D nanomaterials,have been draw-ing attention since the last decade due to their high electronic conduc-tivity,processability,mechanical robustness and chemical tunability.In this review,we encompass the fabrication of MXene-based polymeric nanocomposites,their structure-property relationship,and applications in the flexible sensor domain.Moreover,our discussion is not only lim-ited to sensor design,their mechanism,and various modes of sensing platform,but also their future perspective and market throughout the world.With our article,we intend to fortify the bond between flexible matrices and MXenes thus promoting the swift advancement of flexible MXene-sensors for wearable technologies. 展开更多
关键词 Flexible sensor 2D nanomaterials MXene Wearable and conductive Applications
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Intelligent Recognition Using Ultralight Multifunctional Nano‑Layered Carbon Aerogel Sensors with Human‑Like Tactile Perception 被引量:4
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作者 Huiqi Zhao Yizheng Zhang +8 位作者 Lei Han Weiqi Qian Jiabin Wang Heting Wu Jingchen Li Yuan Dai Zhengyou Zhang Chris RBowen Ya Yang 《Nano-Micro Letters》 SCIE EI CAS CSCD 2024年第1期172-186,共15页
Humans can perceive our complex world through multi-sensory fusion.Under limited visual conditions,people can sense a variety of tactile signals to identify objects accurately and rapidly.However,replicating this uniq... Humans can perceive our complex world through multi-sensory fusion.Under limited visual conditions,people can sense a variety of tactile signals to identify objects accurately and rapidly.However,replicating this unique capability in robots remains a significant challenge.Here,we present a new form of ultralight multifunctional tactile nano-layered carbon aerogel sensor that provides pressure,temperature,material recognition and 3D location capabilities,which is combined with multimodal supervised learning algorithms for object recognition.The sensor exhibits human-like pressure(0.04–100 kPa)and temperature(21.5–66.2℃)detection,millisecond response times(11 ms),a pressure sensitivity of 92.22 kPa^(−1)and triboelectric durability of over 6000 cycles.The devised algorithm has universality and can accommodate a range of application scenarios.The tactile system can identify common foods in a kitchen scene with 94.63%accuracy and explore the topographic and geomorphic features of a Mars scene with 100%accuracy.This sensing approach empowers robots with versatile tactile perception to advance future society toward heightened sensing,recognition and intelligence. 展开更多
关键词 Multifunctional sensor Tactile perception Multimodal machine learning algorithms Universal tactile system Intelligent object recognition
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