Background: Leaf Area Index(LAI) is an important parameter used in monitoring and modeling of forest ecosystems. The aim of this study was to evaluate performance of the artificial neural network(ANN) models to predic...Background: Leaf Area Index(LAI) is an important parameter used in monitoring and modeling of forest ecosystems. The aim of this study was to evaluate performance of the artificial neural network(ANN) models to predict the LAI by comparing the regression analysis models as the classical method in these pure and even-aged Crimean pine forest stands.Methods: One hundred eight temporary sample plots were collected from Crimean pine forest stands to estimate stand parameters. Each sample plot was imaged with hemispherical photographs to detect the LAI. The partial correlation analysis was used to assess the relationships between the stand LAI values and stand parameters, and the multivariate linear regression analysis was used to predict the LAI from stand parameters. Different artificial neural network models comprising different number of neuron and transfer functions were trained and used to predict the LAI of forest stands.Results: The correlation coefficients between LAI and stand parameters(stand number of trees, basal area, the quadratic mean diameter, stand density and stand age) were significant at the level of 0.01. The stand age, number of trees, site index, and basal area were independent parameters in the most successful regression model predicted LAI values using stand parameters(R_(adj)~2=0.5431). As corresponding method to predict the interactions between the stand LAI values and stand parameters, the neural network architecture based on the RBF 4-19-1 with Gaussian activation function in hidden layer and the identity activation function in output layer performed better in predicting LAI(SSE(12.1040), MSE(0.1223), RMSE(0.3497), AIC(0.1040), BIC(-77.7310) and R^2(0.6392)) compared to the other studied techniques.Conclusion: The ANN outperformed the multivariate regression techniques in predicting LAI from stand parameters. The ANN models, developed in this study, may aid in making forest management planning in study forest stands.展开更多
Heavy metal pollution in soil-plant system is of major environmental concern on a world scale and in China in particular with the rapid development of industry. The heavy metal pollution status in soil-plant system in...Heavy metal pollution in soil-plant system is of major environmental concern on a world scale and in China in particular with the rapid development of industry. The heavy metal pollution status in soil-plant system in China, the research progress on the bioavailability of heavy metals (affecting factors, extraction methods, free-ion activity model, adsorption model, multivariate regression model, Q-I relationship, and compound pollution), and soil remediation are reviewed in the paper. Future research and monitoring is also discussed.展开更多
Let{X_(ni),F_(ni);1≤i≤n,n≥1}be an array of R^(d)martingale difference random vectors and{A_(ni),1≤i≤n,n≥1}be an array of m×d matrices of real numbers.In this paper,the Marcinkiewicz-Zygmund type weak law of...Let{X_(ni),F_(ni);1≤i≤n,n≥1}be an array of R^(d)martingale difference random vectors and{A_(ni),1≤i≤n,n≥1}be an array of m×d matrices of real numbers.In this paper,the Marcinkiewicz-Zygmund type weak law of large numbers for maximal weighted sums of martingale difference random vectors is obtained with not necessarily finite p-th(1<p<2)moments.Moreover,the complete convergence and strong law of large numbers are established under some mild conditions.An application to multivariate simple linear regression model is also provided.展开更多
The elevated-temperature deformation behavior of Ti2AlNb superalloy was observed by isothermal compression experiments in a wide range of temperatures(950–1200°C)and strain rates(0.001–10 s^(-1)).The flow behav...The elevated-temperature deformation behavior of Ti2AlNb superalloy was observed by isothermal compression experiments in a wide range of temperatures(950–1200°C)and strain rates(0.001–10 s^(-1)).The flow behavior is nonlinear,strongly coupled,and multivariable.The constitutive models,namely the double multivariate nonlinear regression model,artificial neural network model,and modified artificial neural network model with an explicit expression,were applied to describe the Ti2AlNb superalloy plastic deformation behavior.The comparative predictability of those constitutive models was further evaluated by considering the correlation coefficient and average absolute relative error.The comparative results show that the modified artificial network model can describe the flow stress of Ti2AlNb superalloy more accurately than the other developed constitutive models.The explicit expression obtained from the modified artificial neural network model can be directly used for finite element simulation.The modified artificial neural network model solves the problems that the double multivariate nonlinear regression model cannot describe the nonlinear,strongly coupled,and multivariable flow behavior of Ti2AlNb superalloy accurately,and the artificial neural network model cannot be embedded into the finite element software directly.However,the modified artificial neural network model is mainly dependent on the quantity of high-quality experimental data and characteristic variables,and the modified artificial neural network model has not physical meanings.Besides,the processing maps were applied to obtain the optimum processing parameters.展开更多
Background The transmission dynamics and severity of coronavirus disease 2019(COVID-19)pandemic is different across countries or regions.Differences in governments’policy responses may explain some of these differenc...Background The transmission dynamics and severity of coronavirus disease 2019(COVID-19)pandemic is different across countries or regions.Differences in governments’policy responses may explain some of these differences.We aimed to compare worldwide government responses to the spread of COVID-19,to examine the relationship between response level,response timing and the epidemic trajectory.Methods Free publicly-accessible data collected by the Coronavirus Government Response Tracker(OxCGRT)were used.Nine sub-indicators reflecting government response from 148 countries were collected systematically from January 1 to May 1,2020.The sub-indicators were scored and were aggregated into a common Stringency Index(SI,a value between 0 and 100)that reflects the overall stringency of the government’s response in a daily basis.Group-based trajectory modelling method was used to identify trajectories of SI.Multivariable linear regression models were used to analyse the association between time to reach a high-level SI and time to the peak number of daily new cases.Results Our results identified four trajectories of response in the spread of COVID-19 based on when the response was initiated:before January 13,from January 13 to February 12,from February 12 to March 11,and the last stage—from March 11(the day WHO declared a pandemic of COVID-19)on going.Governments’responses were upgraded with further spread of COVID-19 but varied substantially across countries.After the adjustment of SI level,geographical region and initiation stages,each day earlier to a high SI level(SI>80)from the start of response was associated with 0.44(standard error:0.08,P<0.001,R2=0.65)days earlier to the peak number of daily new case.Also,each day earlier to a high SI level from the date of first reported case was associated with 0.65(standard error:0.08,P<0.001,R2=0.42)days earlier to the peak number of daily new case.Conclusions Early start of a high-level response to COVID-19 is associated with early arrival of the peak number of daily new cases.This may help to reduce the delays in flattening the epidemic curve to the low spread level.展开更多
Objective: In this study, we aimed to expand current knowledge of head and neck squamous cell carcinoma (HNSCC)-associated long noncoding RNAs (IncRNAs), and to discover potential IncRNA prognostic biomarkers for...Objective: In this study, we aimed to expand current knowledge of head and neck squamous cell carcinoma (HNSCC)-associated long noncoding RNAs (IncRNAs), and to discover potential IncRNA prognostic biomarkers for HNSCC based on next-generation RNA-seq. Methods: RNA-seq data of 546 samples from patients with HNSCC were downloaded from The Cancer Genome Atlas (TCGA), including 43 paired samples of tumor tissue and adjacent normal tissue. An integrated analysis incorporating differential expression, weighted gene co-expression networks, functional enrichment, clinical parameters, and survival analysis was conducted to discover HNSCC-associated IncRNAs. The function of CYTOR was verified by cell-based experiments. To further identify IncRNAs with prognostic significance, a multivariate Cox proportional hazard regression analysis was performed. The identified IncRNAs were validated with an independent cohort using clinical feature relevance analysis and multivariate Cox regression analysis. Results: We identified nine HNSCC-relevant IncRNAs likely to play pivotal roles in HNSCC onset and development. By functional enrichment analysis, we revealed that CYTOR might participate in the multistep pathological processes of cancer, such as ribosome biogenesis and maintenance of genomic stability. CY-I-OR was identified to be positively correlated with lymph node metastasis, and significantly negatively correlated with overall survival (OS) and disease free survival (DFS) of HNSCC patients. Moreover, CYTOR inhibited cell apoptosis following treatment with the chemotherapeutic drug diamminedichloroplatinum (DDP). HCG22, the most dramatically down-regulated IncRNA in tumor tissue, may function in epidermis differentiation. It was also significantly associated with several clinical features of patients with HNSCC, and positively correlated with patient survival. CYTOR and HCG22 maintained their prognostic values in- dependent of several clinical features in multivariate Cox hazards analysis. Notably, validation either based on an independent HNSCC cohort or by laboratory experiments confirmed these findings. Conclusions: Our transcriptomic analysis suggested that dysregulation of these HNSCC-associated IncRNAs might be involved in HNSCC oncogenesis and progression. Moreover, CYTOR and HCG22 were confirmed as two independent prognostic factors for HNSCC patient survival, providing new insights into the roles of these IncRNAs in HNSCC as well as clinical applications.展开更多
Gushes of Internet public opinions may trigger unexpected incidents that significantly affectsocial security and stability, especially for ones caused by the failure of public policies. Therefore,forecasting this kind...Gushes of Internet public opinions may trigger unexpected incidents that significantly affectsocial security and stability, especially for ones caused by the failure of public policies. Therefore,forecasting this kind of Interact public opinions is of great significance. The duration could be citedas one of the most direct indicators that can reflect the severity of a specific Internet public opinioncase. Based on this background, this paper aims to find the factors that may affect the duration of Internet public opinions, and accordingly proposes a model that can accurately predict the durationbefore the release of public policies. Specifically, an index system including 8 factors by consideringfour dimensions, namely, object, environment, reality (offline), and the network (online), isestablished. In addition, based on the dataset containing 23 typical Internet public opinion casescaused by the failure of public policies, 9 prediction models are gained by applying the multivariatelinear regression model, multivariate nonlinear regression model, and the Cobb-Douglas function.展开更多
基金Funding from The Scientific and Technological Research Council of Turkey(Project No:2130026)is gratefully acknowledged
文摘Background: Leaf Area Index(LAI) is an important parameter used in monitoring and modeling of forest ecosystems. The aim of this study was to evaluate performance of the artificial neural network(ANN) models to predict the LAI by comparing the regression analysis models as the classical method in these pure and even-aged Crimean pine forest stands.Methods: One hundred eight temporary sample plots were collected from Crimean pine forest stands to estimate stand parameters. Each sample plot was imaged with hemispherical photographs to detect the LAI. The partial correlation analysis was used to assess the relationships between the stand LAI values and stand parameters, and the multivariate linear regression analysis was used to predict the LAI from stand parameters. Different artificial neural network models comprising different number of neuron and transfer functions were trained and used to predict the LAI of forest stands.Results: The correlation coefficients between LAI and stand parameters(stand number of trees, basal area, the quadratic mean diameter, stand density and stand age) were significant at the level of 0.01. The stand age, number of trees, site index, and basal area were independent parameters in the most successful regression model predicted LAI values using stand parameters(R_(adj)~2=0.5431). As corresponding method to predict the interactions between the stand LAI values and stand parameters, the neural network architecture based on the RBF 4-19-1 with Gaussian activation function in hidden layer and the identity activation function in output layer performed better in predicting LAI(SSE(12.1040), MSE(0.1223), RMSE(0.3497), AIC(0.1040), BIC(-77.7310) and R^2(0.6392)) compared to the other studied techniques.Conclusion: The ANN outperformed the multivariate regression techniques in predicting LAI from stand parameters. The ANN models, developed in this study, may aid in making forest management planning in study forest stands.
文摘Heavy metal pollution in soil-plant system is of major environmental concern on a world scale and in China in particular with the rapid development of industry. The heavy metal pollution status in soil-plant system in China, the research progress on the bioavailability of heavy metals (affecting factors, extraction methods, free-ion activity model, adsorption model, multivariate regression model, Q-I relationship, and compound pollution), and soil remediation are reviewed in the paper. Future research and monitoring is also discussed.
基金Supported by the Outstanding Youth Research Project of Anhui Colleges(Grant No.2022AH030156)。
文摘Let{X_(ni),F_(ni);1≤i≤n,n≥1}be an array of R^(d)martingale difference random vectors and{A_(ni),1≤i≤n,n≥1}be an array of m×d matrices of real numbers.In this paper,the Marcinkiewicz-Zygmund type weak law of large numbers for maximal weighted sums of martingale difference random vectors is obtained with not necessarily finite p-th(1<p<2)moments.Moreover,the complete convergence and strong law of large numbers are established under some mild conditions.An application to multivariate simple linear regression model is also provided.
基金China National Science and Technology Major Project(Grant No.2017-VI-0004-0075).
文摘The elevated-temperature deformation behavior of Ti2AlNb superalloy was observed by isothermal compression experiments in a wide range of temperatures(950–1200°C)and strain rates(0.001–10 s^(-1)).The flow behavior is nonlinear,strongly coupled,and multivariable.The constitutive models,namely the double multivariate nonlinear regression model,artificial neural network model,and modified artificial neural network model with an explicit expression,were applied to describe the Ti2AlNb superalloy plastic deformation behavior.The comparative predictability of those constitutive models was further evaluated by considering the correlation coefficient and average absolute relative error.The comparative results show that the modified artificial network model can describe the flow stress of Ti2AlNb superalloy more accurately than the other developed constitutive models.The explicit expression obtained from the modified artificial neural network model can be directly used for finite element simulation.The modified artificial neural network model solves the problems that the double multivariate nonlinear regression model cannot describe the nonlinear,strongly coupled,and multivariable flow behavior of Ti2AlNb superalloy accurately,and the artificial neural network model cannot be embedded into the finite element software directly.However,the modified artificial neural network model is mainly dependent on the quantity of high-quality experimental data and characteristic variables,and the modified artificial neural network model has not physical meanings.Besides,the processing maps were applied to obtain the optimum processing parameters.
文摘Background The transmission dynamics and severity of coronavirus disease 2019(COVID-19)pandemic is different across countries or regions.Differences in governments’policy responses may explain some of these differences.We aimed to compare worldwide government responses to the spread of COVID-19,to examine the relationship between response level,response timing and the epidemic trajectory.Methods Free publicly-accessible data collected by the Coronavirus Government Response Tracker(OxCGRT)were used.Nine sub-indicators reflecting government response from 148 countries were collected systematically from January 1 to May 1,2020.The sub-indicators were scored and were aggregated into a common Stringency Index(SI,a value between 0 and 100)that reflects the overall stringency of the government’s response in a daily basis.Group-based trajectory modelling method was used to identify trajectories of SI.Multivariable linear regression models were used to analyse the association between time to reach a high-level SI and time to the peak number of daily new cases.Results Our results identified four trajectories of response in the spread of COVID-19 based on when the response was initiated:before January 13,from January 13 to February 12,from February 12 to March 11,and the last stage—from March 11(the day WHO declared a pandemic of COVID-19)on going.Governments’responses were upgraded with further spread of COVID-19 but varied substantially across countries.After the adjustment of SI level,geographical region and initiation stages,each day earlier to a high SI level(SI>80)from the start of response was associated with 0.44(standard error:0.08,P<0.001,R2=0.65)days earlier to the peak number of daily new case.Also,each day earlier to a high SI level from the date of first reported case was associated with 0.65(standard error:0.08,P<0.001,R2=0.42)days earlier to the peak number of daily new case.Conclusions Early start of a high-level response to COVID-19 is associated with early arrival of the peak number of daily new cases.This may help to reduce the delays in flattening the epidemic curve to the low spread level.
基金Project supported by the National Natural Science Foundation of China(Nos.31471226 and 91440108)the Fundamental Research Funds for the Central Universities(Nos.WK2070000044 and WK2070000034),China
文摘Objective: In this study, we aimed to expand current knowledge of head and neck squamous cell carcinoma (HNSCC)-associated long noncoding RNAs (IncRNAs), and to discover potential IncRNA prognostic biomarkers for HNSCC based on next-generation RNA-seq. Methods: RNA-seq data of 546 samples from patients with HNSCC were downloaded from The Cancer Genome Atlas (TCGA), including 43 paired samples of tumor tissue and adjacent normal tissue. An integrated analysis incorporating differential expression, weighted gene co-expression networks, functional enrichment, clinical parameters, and survival analysis was conducted to discover HNSCC-associated IncRNAs. The function of CYTOR was verified by cell-based experiments. To further identify IncRNAs with prognostic significance, a multivariate Cox proportional hazard regression analysis was performed. The identified IncRNAs were validated with an independent cohort using clinical feature relevance analysis and multivariate Cox regression analysis. Results: We identified nine HNSCC-relevant IncRNAs likely to play pivotal roles in HNSCC onset and development. By functional enrichment analysis, we revealed that CYTOR might participate in the multistep pathological processes of cancer, such as ribosome biogenesis and maintenance of genomic stability. CY-I-OR was identified to be positively correlated with lymph node metastasis, and significantly negatively correlated with overall survival (OS) and disease free survival (DFS) of HNSCC patients. Moreover, CYTOR inhibited cell apoptosis following treatment with the chemotherapeutic drug diamminedichloroplatinum (DDP). HCG22, the most dramatically down-regulated IncRNA in tumor tissue, may function in epidermis differentiation. It was also significantly associated with several clinical features of patients with HNSCC, and positively correlated with patient survival. CYTOR and HCG22 maintained their prognostic values in- dependent of several clinical features in multivariate Cox hazards analysis. Notably, validation either based on an independent HNSCC cohort or by laboratory experiments confirmed these findings. Conclusions: Our transcriptomic analysis suggested that dysregulation of these HNSCC-associated IncRNAs might be involved in HNSCC oncogenesis and progression. Moreover, CYTOR and HCG22 were confirmed as two independent prognostic factors for HNSCC patient survival, providing new insights into the roles of these IncRNAs in HNSCC as well as clinical applications.
文摘Gushes of Internet public opinions may trigger unexpected incidents that significantly affectsocial security and stability, especially for ones caused by the failure of public policies. Therefore,forecasting this kind of Interact public opinions is of great significance. The duration could be citedas one of the most direct indicators that can reflect the severity of a specific Internet public opinioncase. Based on this background, this paper aims to find the factors that may affect the duration of Internet public opinions, and accordingly proposes a model that can accurately predict the durationbefore the release of public policies. Specifically, an index system including 8 factors by consideringfour dimensions, namely, object, environment, reality (offline), and the network (online), isestablished. In addition, based on the dataset containing 23 typical Internet public opinion casescaused by the failure of public policies, 9 prediction models are gained by applying the multivariatelinear regression model, multivariate nonlinear regression model, and the Cobb-Douglas function.