Marx's theory of ground rent is an indispensable part of Marx's economic theory. It is essential to grasp scientific connotation of Marx's theory of ground rent,and actively explore and study theories and ...Marx's theory of ground rent is an indispensable part of Marx's economic theory. It is essential to grasp scientific connotation of Marx's theory of ground rent,and actively explore and study theories and policies of socialist ground rent and nationalization of land through combining the certainty of existence of ground rent and actual situations of nationalization of land in China.展开更多
With the impetus of the WTO and the further opening of China's international service trade in education, this paper is based on the background of China's national strategy "one belt & one road", analyzing Guangzh...With the impetus of the WTO and the further opening of China's international service trade in education, this paper is based on the background of China's national strategy "one belt & one road", analyzing Guangzhou higher education, its internationalization driving force and popularization value, ranging from the perspectives of higher education resources excess, the domestic university funding cuts, and the transnational education services output in developed countries to alleviate its school funds shortage to further introduction of foreign high-quality educational resources due to not fully meeting the requirements of domestic demand in developing and less developed countries, with expectation to promote the development of education internationalization healthily and orderly.展开更多
Since the late 1980s,there has been a resurgence of regionalism in world politics.Prospects for new alliances are opened up often on a regional basis.In East and Southeast Asia,regionalization is becoming evident in h...Since the late 1980s,there has been a resurgence of regionalism in world politics.Prospects for new alliances are opened up often on a regional basis.In East and Southeast Asia,regionalization is becoming evident in higher education,with both awareness and signs of a rising ASEAN+3 higher education community.The quest for regional influence in Southeast Asia,however,has not been immune from controversies.One fact has been China’s growing soft power.As a systematically planned soft power policy,China is projecting soft power actively through higher education in the region.Yet,China-ASEAN relations in higher education have been little documented.Unlike the mainstay of the practices of internationalization in higher education that focuses overwhelmingly on educational exchange and collaboration with affluent Western countries,China’s interactions with ASEAN member countries in higher education are fulfilled by“quiet achievers,”mainly seen at the regional institutions in relatively less developed provinces such as Guangxi and Yunnan.This article selects regional higher education institutions in China’s much disadvantaged provinces to depict a different picture to argue that regionalization could contribute substantially to internationalization,if a variety of factors are combined properly.展开更多
Although national transplant organizations share common visions and goals,the creation of a unified global organization remains impractical.Differences in ethnicity,culture,religion,and education shape local practices...Although national transplant organizations share common visions and goals,the creation of a unified global organization remains impractical.Differences in ethnicity,culture,religion,and education shape local practices and infrastructure,making the establishment of a single global entity unfeasible.Even with these social disparities aside,logistical factors such as time and distance between organ procurement and transplantation sites pose significant challenges.While technological advancements have extended organ preservation times,they have yet to support the demands of transcontinental transplantations effectively.This review presents a comparative analysis of the structures,operational frameworks,policies,and legislation governing various transplant organizations around the world.Key differences pertain to the administration of these organizations,trends in organ donation,and organ allocation policies,which reflect the financial,cultural,and religious diversity across different regions.While a global transplant organization may be out of reach,agreeing on best practices for the benefit of patients is essential.展开更多
BACKGROUND The triglyceride glucose-body mass index(TyG-BMI)is a novel indicator of insulin resistance(IR).Obstructive sleep apnea(OSA)is a prevalent disorder characterized by recurrent complete or partial collapse of...BACKGROUND The triglyceride glucose-body mass index(TyG-BMI)is a novel indicator of insulin resistance(IR).Obstructive sleep apnea(OSA)is a prevalent disorder characterized by recurrent complete or partial collapse of the pharyngeal airway during sleep;however,the relationship between these two conditions remains unexplored.We hypothesized that a higher TyG-BMI is associated with the occurrence of OSA.AIM To assess the association between TyG-BMI and OSA in adults in the United States.METHODS A cross-sectional study was conducted utilizing data from the National Health and Nutrition Examination Surveys spanning from 2005-2008 to 2015-2018.TyGBMI was calculated as Ln[triglyceride(mg/dL)×fasting blood glucose(mg/dL)/2]×BMI.Restricted cubic splines were used to analyze the risk of TyG-BMI and OSA occurrence.To identify potential nonlinear relationships,we combined Cox proportional hazard regression with smooth curve fitting.We also conducted sensitivity and subgroup analyses to verify the robustness of our findings.RESULTS We included 16794 participants in the final analysis.Multivariate regression analysis showed that participants with a higher TyG-BMI had a higher OSA incidence.After adjusting for all covariates,TyG-BMI was positively correlated with the prevalence of OSA(odds ratio:1.28;95%confidence interval:1.17,1.40;P<0.001);no significant nonlinear relationship was observed.Subgroup analysis showed no strong correlation between TyG-BMI and OSA in patients with diabetes.The correlation between TyG-BMI and OSA was influenced by age,sex,smoking status,marital status,hypertensive stratification,and obesity;these subgroups played a moderating role between TyGBMI and OSA.Even after adjusting for all covariates,there was a positive association between TYG-BMI and OSA prevalence.CONCLUSION A higher TyG-BMI index is linked to higher chances of developing OSA.As TyG-BMI is an indicator of IR,managing IR may help reduce the risk of OSA.展开更多
BACKGROUND Identification of myocardial injury has traditionally relied on high-sensitivity troponin T(hs-TnT)levels exceeding the 99th percentile threshold.However,patients with detectable hs-TnT levels below this th...BACKGROUND Identification of myocardial injury has traditionally relied on high-sensitivity troponin T(hs-TnT)levels exceeding the 99th percentile threshold.However,patients with detectable hs-TnT levels below this threshold represent a heterogeneous group with an inadequately characterized risk profile.AIM To investigate the association between hs-TnT levels below the 99th percentile and the presence of diabetic kidney disease(DKD)in patients with diabetes mellitus.METHODS This study analyzed data from the National Health and Nutrition Examination Survey obtained between 1999 and 2004,focusing on adults with type 2 diabetes mellitus.Serum hs-TnT concentrations were evaluated.DKD was defined as impaired glomerular filtration rate(<60 mL/minute/1.73 m^(2)),proteinuria(urinary albumin-to-creatinine ratio of≥30 mg/g),or both conditions in patients with diabetes mellitus.Weighted multivariable logistic regression analysis and restricted cubic spline analyses were employed to examine the independent association between hs-TnT and DKD,with the likelihood ratio test being used to evaluate nonlinearity.RESULTS The study included 2505 patients with a mean age of 55.02(standard error:0.72)years,of whom 44.87%were females.Among the participants,909(32.34%)were diagnosed with DKD.Multivariable logistic regression analysis indicated that,compared to the lowest tertile of hs-TnT(<5.93 ng/L),tertile 2(5.94-9.79 ng/L)had an odds ratio of 1.25(95%confidence interval:0.77-2.02,P=0.350),while tertile 3(9.80-21.88 ng/L)had an odds ratio of 2.07(95%confidence interval:1.13-3.80,P=0.022),with a significant trend(P for trend=0.022).Smoothed curve fitting demonstrated a linear association between hs-TnT levels and DKD in the overall population(P=0.061 for nonlinearity)and in male(P=0.136 for nonlinearity)and female(P=0.067 for nonlinearity)subgroups.Further stratification and sensitivity analyses yielded consistent conclusions.CONCLUSION Our study findings suggest that in individuals with type 2 diabetes,detectable hs-TnT levels below the 99th percentile are associated with DKD.展开更多
AIM:To assess the relationship between dietary inflammatory index(DII)and prevalence of glaucoma among individuals aged 40y and above in the United States.METHODS:Participants were drawn from 2 cycles of the National ...AIM:To assess the relationship between dietary inflammatory index(DII)and prevalence of glaucoma among individuals aged 40y and above in the United States.METHODS:Participants were drawn from 2 cycles of the National Health and Nutrition Examination Survey(NHANES,2005-2008)for a cross-sectional study.DII was calculated from 24-hour dietary recall questionnaire conducted by experienced researchers and data analyzed in R according to the NHANES user guide,“Stratified Multi-stage Probability Sampling”.The relationship between DII and glaucoma was evaluated by multi-factor logistic regression analysis and the existence of a non-linear association examined by restricted cubic spline(RCS)analysis.RESULTS:A total of 5359 subjects were included and the cross-sectional analysis weighted to represent the US population of 109 million.DII was elevated in glaucoma patients(P<0.001)and smoking and alcohol use contributed to significant differences(P<0.001).DII correlated negatively with Healthy Eating Index(HEI)-2015(Spearman rank correlation coefficient,r=-0.49).RCS analysis showed a linear relationship between DII and glaucoma risk(P of non-linear relationship=0.575).CONCLUSION:An increased DII is strongly associated with high risk of glaucoma and diet-induced inflammation should be controlled to delay glaucoma progression.展开更多
Investigating the ecological impact of land use change in the context of the construction of national water network project is crucial,as it is imperative for achieving the sustainable development goals of the nationa...Investigating the ecological impact of land use change in the context of the construction of national water network project is crucial,as it is imperative for achieving the sustainable development goals of the national water network and guaranteeing regional ecological stability.Using the Danjiangkou Reservoir Area(DRA),China as the study area,this paper first examined the spatiotemporal dynamics of natural landscape patterns and ecosystem service values(ESV)in the DRA from 2000 to 2018 and then investigated the spatial clustering characteristics of the ESV using spatial statistical analysis tools.Finally,the patch-generating land use simulation(PLUS)model was used to simulate the natural landscape and future changes in the ESV of the DRA from 2018 to 2028 under four different development scenarios:business as usual(BAU),economic development(ED),ecological protection(EP),and shoreline protection(SP).The results show that:during 2000-2018,the construction of water facilities had a significant impact on regional land use/land cover(LULC)change,with a 24830 ha increase in watershed area.ESV exhibited an increasing trend,with a significant and growing spatial clustering effect.The transformation of farmland to water bodies led to accelerated ESV growth,while the transformation of forest land to farmland led to a decrease in the ESV.Normalized difference vegetation index(NDVI)had the strongest effect on the ESV.ESV exhibited a continuous increase from 2018 to 2028 under all the simulation scenarios.The EP scenario had the greatest increase in ESV,while the ED scenario had the smallest increase.The findings suggest that projected land use patterns under different scenarios have varied impacts on ecosystem services(ESs)and that the management and planning of the DRA should balance social,economic,ecological,and security benefits.nomic,ecological,and security benefits.展开更多
This article focuses on the in-depth analysis of the cultural roots of the introduction and evolution of Chinese Yangqin and its development in China, based on an elaboration of the world distribution of Yangqin. The ...This article focuses on the in-depth analysis of the cultural roots of the introduction and evolution of Chinese Yangqin and its development in China, based on an elaboration of the world distribution of Yangqin. The aim is to illustrate the growth and evolution of the Chinese Yangqin over the past few hundred years, with every detail reflecting deep-seated cultural connotations and aesthetic needs. Therefore, “embodying the beauty of Chinese cultural tradition” remains the internal mechanism for developing Chinese Yangqin.展开更多
Antibacterial resistance is a global health threat that requires further concrete action on the part of all countries.In this context,one of the biggest concerns is whether enough new antibacterial drugs are being dis...Antibacterial resistance is a global health threat that requires further concrete action on the part of all countries.In this context,one of the biggest concerns is whether enough new antibacterial drugs are being discovered and developed.Although several high-quality reviews on clinical antibacterial drug pipelines from a global perspective were published recently,none provides comprehensive information on original antibacterial drugs at clinical stages in China.In this review,we summarize the latest progress of novel antibacterial drugs approved for marketing and under clinical evaluation in China since 2019.Information was obtained by consulting official websites,searching commercial databases,retrieving literature,asking personnel from institutions or companies,and other means,and a considerable part of the data covered here has not been included in other reviews.As of June 30,2023,a total of 20 antibacterial projects from 17 Chinese pharmaceutical companies or developers were identified and updated.Among them,two new antibacterial drugs that belong to traditional antibiotic classes were approved by the National Medical Products Administration(NMPA)in China in 2019 and 2021,respectively,and 18 antibacterial agents are in clinical development,with one under regulatory evaluation,five in phase-3,six in phase-2,and six in phase-1.Most of the clinical candidates are new analogs or monocomponents of traditional antibacterial pharmacophore types,including two dual-acting hybrid antibiotics and a recombinant antibacterial protein.Overall,despite there being 17 antibacterial clinical candidates,our analysis indicates that there are still relatively few clinically differentiated antibacterial agents in stages of clinical development in China.Hopefully,Chinese pharmaceutical companies and institutions will develop more innovative and clinically differentiated candidates with good market potential in the future research and development(R&D)of original antibacterial drugs.展开更多
Due to long-term human activity interference,the Hainan Tropical Rainforest National Park(HTRNP)of China has experienced ecological problems such as habitat fragmentation and biodiversity loss,and with the expanding s...Due to long-term human activity interference,the Hainan Tropical Rainforest National Park(HTRNP)of China has experienced ecological problems such as habitat fragmentation and biodiversity loss,and with the expanding scope and intensity of human activity impact,the regional ecological security is facing serious challenges.A scientific assessment of the interrelationship between human activity intensity and habitat quality in the HTRNP is a prerequisite for achieving effective management of ecological disturbances caused by human activities and can also provide scientific strategies for the sustainable development of the region.Based on the land use change data in 2000,2010,and 2020,the spatial and temporal variations and the relationship between habitat quality(HQ)and human activity intensity(HAI)in the HTRNP were explored using the integrated valuation of ecosystem services and trade-offs(InVEST)model.System dynamics and land use simulation models were also combined to conduct multi-scenario simulations of their relationships.The results showed that during 2000–2020,the habitat quality of the HTRNP improved,the intensity of human activities decreased each year,and there was a negative correlation between the two.Second,the system dynamic model could be well coupled with the land use simulation model by combining socio-economic and natural factors.The simulation scenarios of the coupling model showed that the harmonious development(HD)scenario is effective in curbing the increasing trend of human activity intensity and decreasing trend of habitat quality,with a weaker trade-off between the two compared with the baseline development(BD)and investment priority oriented(IPO)scenarios.To maintain the authenticity and integrity of the HTRNP,effective measures such as ecological corridor construction,ecological restoration,and the implementation of ecological compensation policies need to be strengthened.展开更多
BACKGROUND Gallbladder cancer is the most common malignancy of the biliary tract.Neo-adjuvant chemotherapy(NACT)has improved overall survival by enabling R0 resection.Currently,there is no consensus of guidelines for ...BACKGROUND Gallbladder cancer is the most common malignancy of the biliary tract.Neo-adjuvant chemotherapy(NACT)has improved overall survival by enabling R0 resection.Currently,there is no consensus of guidelines for neoadjuvant therapy in gallbladder cancer.As investigations continue to analyze the regimen and benefit of NACT for ongoing care of gallbladder cancer patients,we examined American College of Surgeons National Surgical Quality Improvement Program(NSQIP)database to determine if there was higher morbidity among the neo-adjuvant group within the 30-day post-operative period.We hypothesized patients who underwent NACT were more likely to have higher post-operative morbidity.AIM To investigate the 30-day post-operative morbidity outcomes between patients who received NACT and underwent surgery and patients who only had surgery.METHODS A retrospective analysis of the targeted hepatectomy NSQIP data between 2015 and 2019 was performed to determine if NACT in gallbladder cancer increased the risk for post-operative morbidity(bile leak,infection rate,rate of converting to open surgery,etc.)compared to the group who only had surgery.To calculate the odds ratio for the primary and secondary outcomes,a crude logistic regression was performed.RESULTS Of the 452 patients,52 patients received NACT prior to surgery.There were no statistically significant differences in the odds of morbidity between the two groups,including bile leak[odds ratio(OR),0.69;95%confidence interval(95%CI):0.16-2.10;P=0.55],superficial wound infection(OR,0.58;95%CI:0.03-3.02;P=0.61),and organ space wound infection(OR,0.63;95%CI:0.18-1.63;P=0.61).CONCLUSION There was no significant difference in the risk of 30-day post-operative morbidity between the NACT and surgery group and the surgery only group.展开更多
Quantitative assessment of organic carbon(OC)stocks in different habitats is crucial in ecology.Understanding the drivers affecting OC stocks across distinct carbon pools is essential for comprehending current pattern...Quantitative assessment of organic carbon(OC)stocks in different habitats is crucial in ecology.Understanding the drivers affecting OC stocks across distinct carbon pools is essential for comprehending current patterns and predicting future changes.Alpine ecosystems,important for atmospheric CO_(2)regulation and highly vulnerable to climate change,are priority study areas.This research aims to estimate OC stocks in different pools(soil,organic horizons,and aboveground vegetation)and identify factors influencing these stocks in an alpine environment.We sampled 146 sites representing six forest types and two grassland types in the Gran Paradiso National Park(northern Italian Alps).Field samples of soils,organic horizons,and data on aboveground trees were collected to assess OC stocks,along with environmental variables.Our findings reveal nuanced variations in OC stocks across different ecosystem components.In grasslands,average soil OC was 5.57 kg m^(-2),while in forests it was 4.11 kg m^(-2).Organic horizons contained an average of 0.70 kg m^(-2),and aboveground vegetation in forests stored 6.61 kg m^(-2).Linear Mixed Models indicate that soil OC is influenced by habitat type,soil type,and elevation.OC in organic horizons is affected by aspect and forest habitat type,with composting further influenced by elevation.These results contribute to OC stock inventories for alpine ecosystems and enhance our understanding of how environmental factors influence carbon storage.Importantly,they underscore the need to consider soil type and other factors beyond land use when modeling OC stocks.This insight has implications for designing effective territorial strategies to address climate change,emphasizing the importance of a multifaceted approach to carbon stock assessment and management in alpine regions.展开更多
Vegetation resilience(VR),providing an objective measure of ecosystem health,has received considerable attention,however,there is still limited understanding of whether the dominant factors differ across different cli...Vegetation resilience(VR),providing an objective measure of ecosystem health,has received considerable attention,however,there is still limited understanding of whether the dominant factors differ across different climate zones.We took the three national parks(Hainan Tropical Rainforest National Park,HTR;Wuyishan National Park,WYS;and Northeast Tiger and Leopard National Park,NTL)of China with less human interference as cases,which are distributed in different climatic zones,including tropical,subtropical and temperate monsoon climates,respectively.Then,we employed the probabilistic decay method to explore the spatio-temporal changes in the VR and their natural driving patterns using Geographically Weighted Regression(GWR)model as well.The results revealed that:(1)from 2000 to 2020,the Normalized Difference Vegetation Index(NDVI)of the three national parks fluctuated between 0.800 and 0.960,exhibiting an overall upward trend,with the mean NDVI of NTL(0.923)>HTR(0.899)>WYS(0.823);(2)the positive trend decay time of vegetation exceeded that of negative trend,indicating vegetation gradual recovery of the three national parks since 2012;(3)the VR of HTR was primarily influenced by elevation,aspect,average annual temperature change(AATC),and average annual precipitation change(AAPC);the WYS'VR was mainly affected by elevation,average annual precipitation(AAP),and AAPC;while the terrain factors(elevation and slope)were the main driving factors of VR in NTL;(4)among the main factors influencing the VR changes,the AAPC had the highest proportion in HTR(66.7%),and the AAP occupied the largest area proportion in WYS(80.4%).While in NTL,elevation served as the main driving factor for the VR,encompassing 64.2%of its area.Consequently,our findings indicated that precipitation factors were the main driving force for the VR changes in HTR and WYS national parks,while elevation was the main factors that drove the VR in NTL.Our research has promoted a deeper understanding of the driving mechanism behind the VR.展开更多
Objective To analyze the epidemiological characteristics and epidemic situation of children with Kashin-Beck disease(KBD)in China,and provide the basis for formulating prevention and control measures.Methods Fixed-poi...Objective To analyze the epidemiological characteristics and epidemic situation of children with Kashin-Beck disease(KBD)in China,and provide the basis for formulating prevention and control measures.Methods Fixed-point monitoring,moving-point monitoring,and full coverage of monitoring were promoted successively from 1990 to 2023.Some children(7-12 years old)underwent clinical and right-hand X-ray examinations every year.According to the KBD diagnosis criteria,clinical and X-ray assessments were used to confirm the diagnosis.Results In 1990,the national KBD detectable rate was 21.01%.X-ray detection decreased to below 10%in 2003 and below 5%in 2007.Between 2010 and 2018,the prevalence of KBD in children was less than 0.4%,which fluctuated at a low level,and has decreased to 0%since 2019.Spatial epidemiological analysis indicated a spatial clustering of adult patients prevalence rate in the KBD areas.Conclusion The evaluation results of the elimination of KBD in China over the last 5 years showed that all villages in the monitored areas have reached the elimination standard.While the adult KBD patients still need for policy consideration and care.展开更多
COVID-19 posed challenges for global tourism management.Changes in visitor temporal and spatial patterns and their associated determinants pre-and peri-pandemic in Canadian Rocky Mountain National Parks are analyzed.D...COVID-19 posed challenges for global tourism management.Changes in visitor temporal and spatial patterns and their associated determinants pre-and peri-pandemic in Canadian Rocky Mountain National Parks are analyzed.Data was collected through social media programming and analyzed using spatiotemporal analysis and a geographically weighted regression(GWR)model.Results highlight that COVID-19 significantly changed park visitation patterns.Visitors tended to explore more remote areas peri-pandemic.The GWR model also indicated distance to nearby trails was a significant influence on visitor density.Our results indicate that the pandemic influenced tourism temporal and spatial imbalance.This research presents a novel approach using combined social media big data which can be extended to the field of tourism management,and has important implications to manage visitor patterns and to allocate resources efficiently to satisfy multiple objectives of park management.展开更多
Since the Beijing 2022 Winter Olympics was the first Winter Olympics in history held in continental winter monsoon climate conditions across complex terrain areas,there is a deficiency of relevant research,operational...Since the Beijing 2022 Winter Olympics was the first Winter Olympics in history held in continental winter monsoon climate conditions across complex terrain areas,there is a deficiency of relevant research,operational techniques,and experience.This made providing meteorological services for this event particularly challenging.The China Meteorological Administration(CMA)Earth System Modeling and Prediction Centre,achieved breakthroughs in research on short-and medium-term deterministic and ensemble numerical predictions.Several key technologies crucial for precise winter weather services during the Winter Olympics were developed.A comprehensive framework,known as the Operational System for High-Precision Weather Forecasting for the Winter Olympics,was established.Some of these advancements represent the highest level of capabilities currently available in China.The meteorological service provided to the Beijing 2022 Games also exceeded previous Winter Olympic Games in both variety and quality.This included achievements such as the“100-meter level,minute level”downscaled spatiotemporal resolution and forecasts spanning 1 to 15 days.Around 30 new technologies and over 60 kinds of products that align with the requirements of the Winter Olympics Organizing Committee were developed,and many of these techniques have since been integrated into the CMA’s operational national forecasting systems.These accomplishments were facilitated by a dedicated weather forecasting and research initiative,in conjunction with the preexisting real-time operational forecasting systems of the CMA.This program represents one of the five subprograms of the WMO’s high-impact weather forecasting demonstration project(SMART2022),and continues to play an important role in their Regional Association(RA)II Research Development Project(Hangzhou RDP).Therefore,the research accomplishments and meteorological service experiences from this program will be carried forward into forthcoming highimpact weather forecasting activities.This article provides an overview and assessment of this program and the operational national forecasting systems.展开更多
Objective:To describe the situation of measles in Sri Lanka from May to November,2023 and to define the role of virology laboratory towards case confirmation and epidemiological and genetic characterization of the out...Objective:To describe the situation of measles in Sri Lanka from May to November,2023 and to define the role of virology laboratory towards case confirmation and epidemiological and genetic characterization of the outbreak.Methods:This retrospective study analyzed all samples tested for measles from 1st of May to 30th of November,2023 at National Measles Rubella Laboratory,Sri Lanka.According to the World Health Organization(WHO)algorithm,serum and oropharyngeal/nasopharyngeal swabs were tested with WHO recommended kits for anti-measles IgM and measles virus specific RNA,respectively.Selected RNA positive samples were sequenced at reference laboratory,India.Analysis of sequencing data and construction of phylogenetic tree were carried out at National Measles Rubella Laboratory.Data was analyzed using descriptive statistics.Results:Of the total 1132 serum samples and 497 oropharyngeal/nasopharyngeal swabs from 1326 patients,657(49.5%)patients were confirmed as measles by anti-measles IgM,measles virus specific RNA or both.Males(55.6%,n=365)and the age group from>20 to≤30 years(33.0%,n=217)predominated positive patients.All provinces reported measles positive cases.All samples sequenced(100%,n=42)were genotype D8 with 95.2%(n=40)bearing Victoria.Australia origin.Conclusions:We described resurgence of measles in an eliminated country,confirming the genotype to be D8,one of the two genotypes currently circulating globally.Further,the study strongly convinced the importance of a strengthened virological surveillance system in an eliminated country,despite its eliminated status.展开更多
The National Natural Science Foundation of China is one of the major funding agencies for neuro rehabilitation research in China.This study reviews the frontier directions and achievements in the field of neurorehabil...The National Natural Science Foundation of China is one of the major funding agencies for neuro rehabilitation research in China.This study reviews the frontier directions and achievements in the field of neurorehabilitation in China and wo rldwide.We used data from the Web of Science Core Collection(WoSCC) database to analyze the publications and data provided by the National Natural Science Foundation of China to analyze funding information.In addition,the prospects for neurorehabilitation research in China are discussed.From 2010 to 2022,a total of 74,220 publications in neurorehabilitation were identified,with there being an overall upward tendency.During this period,the National Natural Science Foundation of China has funded 476 research projects with a total funding of 192.38 million RMB to support neuro rehabilitation research in China.With the support of the National Natural Science Foundation of China,China has made some achievements in neurorehabilitation research.Research related to neurorehabilitation is believed to be making steady and significant progress in China.展开更多
During the 10th Chinese Arctic scientific expedition carried out in the summer of 2019,the surface current in the high-latitude areas of the Arctic Ocean was observed using a self-developed surface drifting buoy,which...During the 10th Chinese Arctic scientific expedition carried out in the summer of 2019,the surface current in the high-latitude areas of the Arctic Ocean was observed using a self-developed surface drifting buoy,which was initially deployed in the Chukchi Sea.The buoy traversed the Chukchi Sea,Chukchi Abyssal Plain,Mendeleev Ridge,Makarov Basin,and Canada Basin over a period of 632 d.After returning to the Mendeleev Ridge,it continued to drift toward the pole.Overall,the track of the buoy reflected the characteristics of the transpolar drift and Chukchi Slope Current,as well as the inertial flow,cross-ridge surface flow,and even the surface disorganized flow for some time intervals.The results showed that:(1)the transpolar drift mainly occurs in the Chukchi Abyssal Plain,Mendeleev Ridge,and western Canada Basin to the east of the ridge where sea ice concentration is high,and the average northward flow velocity in the region between 79.41°N and 86.32°N was 5.1 cm/s;(2)the average surface velocity of the Chukchi Slope Current was 13.5 cm/s,and while this current moves westward along the continental slope,it also extends northwestward across the continental slope and flows to the deep sea;and(3)when sea ice concentration was less than 50%,the inertial flow was more significant(the maximum observed inertial flow was 26 cm/s,and the radius of the inertia circle was 3.6 km).展开更多
文摘Marx's theory of ground rent is an indispensable part of Marx's economic theory. It is essential to grasp scientific connotation of Marx's theory of ground rent,and actively explore and study theories and policies of socialist ground rent and nationalization of land through combining the certainty of existence of ground rent and actual situations of nationalization of land in China.
文摘With the impetus of the WTO and the further opening of China's international service trade in education, this paper is based on the background of China's national strategy "one belt & one road", analyzing Guangzhou higher education, its internationalization driving force and popularization value, ranging from the perspectives of higher education resources excess, the domestic university funding cuts, and the transnational education services output in developed countries to alleviate its school funds shortage to further introduction of foreign high-quality educational resources due to not fully meeting the requirements of domestic demand in developing and less developed countries, with expectation to promote the development of education internationalization healthily and orderly.
文摘Since the late 1980s,there has been a resurgence of regionalism in world politics.Prospects for new alliances are opened up often on a regional basis.In East and Southeast Asia,regionalization is becoming evident in higher education,with both awareness and signs of a rising ASEAN+3 higher education community.The quest for regional influence in Southeast Asia,however,has not been immune from controversies.One fact has been China’s growing soft power.As a systematically planned soft power policy,China is projecting soft power actively through higher education in the region.Yet,China-ASEAN relations in higher education have been little documented.Unlike the mainstay of the practices of internationalization in higher education that focuses overwhelmingly on educational exchange and collaboration with affluent Western countries,China’s interactions with ASEAN member countries in higher education are fulfilled by“quiet achievers,”mainly seen at the regional institutions in relatively less developed provinces such as Guangxi and Yunnan.This article selects regional higher education institutions in China’s much disadvantaged provinces to depict a different picture to argue that regionalization could contribute substantially to internationalization,if a variety of factors are combined properly.
文摘Although national transplant organizations share common visions and goals,the creation of a unified global organization remains impractical.Differences in ethnicity,culture,religion,and education shape local practices and infrastructure,making the establishment of a single global entity unfeasible.Even with these social disparities aside,logistical factors such as time and distance between organ procurement and transplantation sites pose significant challenges.While technological advancements have extended organ preservation times,they have yet to support the demands of transcontinental transplantations effectively.This review presents a comparative analysis of the structures,operational frameworks,policies,and legislation governing various transplant organizations around the world.Key differences pertain to the administration of these organizations,trends in organ donation,and organ allocation policies,which reflect the financial,cultural,and religious diversity across different regions.While a global transplant organization may be out of reach,agreeing on best practices for the benefit of patients is essential.
基金Supported by Sanming Project of Medicine in Shenzhen,No.SZZYSM202202010。
文摘BACKGROUND The triglyceride glucose-body mass index(TyG-BMI)is a novel indicator of insulin resistance(IR).Obstructive sleep apnea(OSA)is a prevalent disorder characterized by recurrent complete or partial collapse of the pharyngeal airway during sleep;however,the relationship between these two conditions remains unexplored.We hypothesized that a higher TyG-BMI is associated with the occurrence of OSA.AIM To assess the association between TyG-BMI and OSA in adults in the United States.METHODS A cross-sectional study was conducted utilizing data from the National Health and Nutrition Examination Surveys spanning from 2005-2008 to 2015-2018.TyGBMI was calculated as Ln[triglyceride(mg/dL)×fasting blood glucose(mg/dL)/2]×BMI.Restricted cubic splines were used to analyze the risk of TyG-BMI and OSA occurrence.To identify potential nonlinear relationships,we combined Cox proportional hazard regression with smooth curve fitting.We also conducted sensitivity and subgroup analyses to verify the robustness of our findings.RESULTS We included 16794 participants in the final analysis.Multivariate regression analysis showed that participants with a higher TyG-BMI had a higher OSA incidence.After adjusting for all covariates,TyG-BMI was positively correlated with the prevalence of OSA(odds ratio:1.28;95%confidence interval:1.17,1.40;P<0.001);no significant nonlinear relationship was observed.Subgroup analysis showed no strong correlation between TyG-BMI and OSA in patients with diabetes.The correlation between TyG-BMI and OSA was influenced by age,sex,smoking status,marital status,hypertensive stratification,and obesity;these subgroups played a moderating role between TyGBMI and OSA.Even after adjusting for all covariates,there was a positive association between TYG-BMI and OSA prevalence.CONCLUSION A higher TyG-BMI index is linked to higher chances of developing OSA.As TyG-BMI is an indicator of IR,managing IR may help reduce the risk of OSA.
基金This study was approved by the Medical Ethics Committee of the Second Affiliated Hospital of Gannan Medical University(approval No.EFYJ20240113007).
文摘BACKGROUND Identification of myocardial injury has traditionally relied on high-sensitivity troponin T(hs-TnT)levels exceeding the 99th percentile threshold.However,patients with detectable hs-TnT levels below this threshold represent a heterogeneous group with an inadequately characterized risk profile.AIM To investigate the association between hs-TnT levels below the 99th percentile and the presence of diabetic kidney disease(DKD)in patients with diabetes mellitus.METHODS This study analyzed data from the National Health and Nutrition Examination Survey obtained between 1999 and 2004,focusing on adults with type 2 diabetes mellitus.Serum hs-TnT concentrations were evaluated.DKD was defined as impaired glomerular filtration rate(<60 mL/minute/1.73 m^(2)),proteinuria(urinary albumin-to-creatinine ratio of≥30 mg/g),or both conditions in patients with diabetes mellitus.Weighted multivariable logistic regression analysis and restricted cubic spline analyses were employed to examine the independent association between hs-TnT and DKD,with the likelihood ratio test being used to evaluate nonlinearity.RESULTS The study included 2505 patients with a mean age of 55.02(standard error:0.72)years,of whom 44.87%were females.Among the participants,909(32.34%)were diagnosed with DKD.Multivariable logistic regression analysis indicated that,compared to the lowest tertile of hs-TnT(<5.93 ng/L),tertile 2(5.94-9.79 ng/L)had an odds ratio of 1.25(95%confidence interval:0.77-2.02,P=0.350),while tertile 3(9.80-21.88 ng/L)had an odds ratio of 2.07(95%confidence interval:1.13-3.80,P=0.022),with a significant trend(P for trend=0.022).Smoothed curve fitting demonstrated a linear association between hs-TnT levels and DKD in the overall population(P=0.061 for nonlinearity)and in male(P=0.136 for nonlinearity)and female(P=0.067 for nonlinearity)subgroups.Further stratification and sensitivity analyses yielded consistent conclusions.CONCLUSION Our study findings suggest that in individuals with type 2 diabetes,detectable hs-TnT levels below the 99th percentile are associated with DKD.
基金Supported by the National Natural Science Foundation of China(No.82074500)CACMS Innovation Fund(No.CI2021A02605)+1 种基金Administration of Traditional Chinese Medicine of Zhejiang Province(No.2024ZR029)Science and Technology Program of Wenzhou City(No.Y2023210).
文摘AIM:To assess the relationship between dietary inflammatory index(DII)and prevalence of glaucoma among individuals aged 40y and above in the United States.METHODS:Participants were drawn from 2 cycles of the National Health and Nutrition Examination Survey(NHANES,2005-2008)for a cross-sectional study.DII was calculated from 24-hour dietary recall questionnaire conducted by experienced researchers and data analyzed in R according to the NHANES user guide,“Stratified Multi-stage Probability Sampling”.The relationship between DII and glaucoma was evaluated by multi-factor logistic regression analysis and the existence of a non-linear association examined by restricted cubic spline(RCS)analysis.RESULTS:A total of 5359 subjects were included and the cross-sectional analysis weighted to represent the US population of 109 million.DII was elevated in glaucoma patients(P<0.001)and smoking and alcohol use contributed to significant differences(P<0.001).DII correlated negatively with Healthy Eating Index(HEI)-2015(Spearman rank correlation coefficient,r=-0.49).RCS analysis showed a linear relationship between DII and glaucoma risk(P of non-linear relationship=0.575).CONCLUSION:An increased DII is strongly associated with high risk of glaucoma and diet-induced inflammation should be controlled to delay glaucoma progression.
基金Under the auspices of National Natural Science Foundation of China(No.42371315,41901213)Natural Science Foundation of Hubei Province(No.2020CFB856)Project of Changjiang Survey,Planning,Design and Research Co.,Ltd(No.CX2022Z23)。
文摘Investigating the ecological impact of land use change in the context of the construction of national water network project is crucial,as it is imperative for achieving the sustainable development goals of the national water network and guaranteeing regional ecological stability.Using the Danjiangkou Reservoir Area(DRA),China as the study area,this paper first examined the spatiotemporal dynamics of natural landscape patterns and ecosystem service values(ESV)in the DRA from 2000 to 2018 and then investigated the spatial clustering characteristics of the ESV using spatial statistical analysis tools.Finally,the patch-generating land use simulation(PLUS)model was used to simulate the natural landscape and future changes in the ESV of the DRA from 2018 to 2028 under four different development scenarios:business as usual(BAU),economic development(ED),ecological protection(EP),and shoreline protection(SP).The results show that:during 2000-2018,the construction of water facilities had a significant impact on regional land use/land cover(LULC)change,with a 24830 ha increase in watershed area.ESV exhibited an increasing trend,with a significant and growing spatial clustering effect.The transformation of farmland to water bodies led to accelerated ESV growth,while the transformation of forest land to farmland led to a decrease in the ESV.Normalized difference vegetation index(NDVI)had the strongest effect on the ESV.ESV exhibited a continuous increase from 2018 to 2028 under all the simulation scenarios.The EP scenario had the greatest increase in ESV,while the ED scenario had the smallest increase.The findings suggest that projected land use patterns under different scenarios have varied impacts on ecosystem services(ESs)and that the management and planning of the DRA should balance social,economic,ecological,and security benefits.nomic,ecological,and security benefits.
文摘This article focuses on the in-depth analysis of the cultural roots of the introduction and evolution of Chinese Yangqin and its development in China, based on an elaboration of the world distribution of Yangqin. The aim is to illustrate the growth and evolution of the Chinese Yangqin over the past few hundred years, with every detail reflecting deep-seated cultural connotations and aesthetic needs. Therefore, “embodying the beauty of Chinese cultural tradition” remains the internal mechanism for developing Chinese Yangqin.
基金supported by the National Natural Science Foundation of China(32141003 and 82330110)the CAMS Innovation Fund for Medical Sciences(CIFMS+2 种基金2021-I2M-1-039)the National Science and Technology Infrastructure of China(National Pathogen Resource Center-NPRC-32)the Fundamental Research Funds for the Central Universities(2021-PT350-001).
文摘Antibacterial resistance is a global health threat that requires further concrete action on the part of all countries.In this context,one of the biggest concerns is whether enough new antibacterial drugs are being discovered and developed.Although several high-quality reviews on clinical antibacterial drug pipelines from a global perspective were published recently,none provides comprehensive information on original antibacterial drugs at clinical stages in China.In this review,we summarize the latest progress of novel antibacterial drugs approved for marketing and under clinical evaluation in China since 2019.Information was obtained by consulting official websites,searching commercial databases,retrieving literature,asking personnel from institutions or companies,and other means,and a considerable part of the data covered here has not been included in other reviews.As of June 30,2023,a total of 20 antibacterial projects from 17 Chinese pharmaceutical companies or developers were identified and updated.Among them,two new antibacterial drugs that belong to traditional antibiotic classes were approved by the National Medical Products Administration(NMPA)in China in 2019 and 2021,respectively,and 18 antibacterial agents are in clinical development,with one under regulatory evaluation,five in phase-3,six in phase-2,and six in phase-1.Most of the clinical candidates are new analogs or monocomponents of traditional antibacterial pharmacophore types,including two dual-acting hybrid antibiotics and a recombinant antibacterial protein.Overall,despite there being 17 antibacterial clinical candidates,our analysis indicates that there are still relatively few clinically differentiated antibacterial agents in stages of clinical development in China.Hopefully,Chinese pharmaceutical companies and institutions will develop more innovative and clinically differentiated candidates with good market potential in the future research and development(R&D)of original antibacterial drugs.
基金Under the auspices of the National Social Science Found of China(No.21XGL019)Hainan Provincial Natural Science Foundation of China(No.421RC1034)Professor/Doctor Research Foundation of Huizhou University(No.2022JB080)。
文摘Due to long-term human activity interference,the Hainan Tropical Rainforest National Park(HTRNP)of China has experienced ecological problems such as habitat fragmentation and biodiversity loss,and with the expanding scope and intensity of human activity impact,the regional ecological security is facing serious challenges.A scientific assessment of the interrelationship between human activity intensity and habitat quality in the HTRNP is a prerequisite for achieving effective management of ecological disturbances caused by human activities and can also provide scientific strategies for the sustainable development of the region.Based on the land use change data in 2000,2010,and 2020,the spatial and temporal variations and the relationship between habitat quality(HQ)and human activity intensity(HAI)in the HTRNP were explored using the integrated valuation of ecosystem services and trade-offs(InVEST)model.System dynamics and land use simulation models were also combined to conduct multi-scenario simulations of their relationships.The results showed that during 2000–2020,the habitat quality of the HTRNP improved,the intensity of human activities decreased each year,and there was a negative correlation between the two.Second,the system dynamic model could be well coupled with the land use simulation model by combining socio-economic and natural factors.The simulation scenarios of the coupling model showed that the harmonious development(HD)scenario is effective in curbing the increasing trend of human activity intensity and decreasing trend of habitat quality,with a weaker trade-off between the two compared with the baseline development(BD)and investment priority oriented(IPO)scenarios.To maintain the authenticity and integrity of the HTRNP,effective measures such as ecological corridor construction,ecological restoration,and the implementation of ecological compensation policies need to be strengthened.
文摘BACKGROUND Gallbladder cancer is the most common malignancy of the biliary tract.Neo-adjuvant chemotherapy(NACT)has improved overall survival by enabling R0 resection.Currently,there is no consensus of guidelines for neoadjuvant therapy in gallbladder cancer.As investigations continue to analyze the regimen and benefit of NACT for ongoing care of gallbladder cancer patients,we examined American College of Surgeons National Surgical Quality Improvement Program(NSQIP)database to determine if there was higher morbidity among the neo-adjuvant group within the 30-day post-operative period.We hypothesized patients who underwent NACT were more likely to have higher post-operative morbidity.AIM To investigate the 30-day post-operative morbidity outcomes between patients who received NACT and underwent surgery and patients who only had surgery.METHODS A retrospective analysis of the targeted hepatectomy NSQIP data between 2015 and 2019 was performed to determine if NACT in gallbladder cancer increased the risk for post-operative morbidity(bile leak,infection rate,rate of converting to open surgery,etc.)compared to the group who only had surgery.To calculate the odds ratio for the primary and secondary outcomes,a crude logistic regression was performed.RESULTS Of the 452 patients,52 patients received NACT prior to surgery.There were no statistically significant differences in the odds of morbidity between the two groups,including bile leak[odds ratio(OR),0.69;95%confidence interval(95%CI):0.16-2.10;P=0.55],superficial wound infection(OR,0.58;95%CI:0.03-3.02;P=0.61),and organ space wound infection(OR,0.63;95%CI:0.18-1.63;P=0.61).CONCLUSION There was no significant difference in the risk of 30-day post-operative morbidity between the NACT and surgery group and the surgery only group.
文摘Quantitative assessment of organic carbon(OC)stocks in different habitats is crucial in ecology.Understanding the drivers affecting OC stocks across distinct carbon pools is essential for comprehending current patterns and predicting future changes.Alpine ecosystems,important for atmospheric CO_(2)regulation and highly vulnerable to climate change,are priority study areas.This research aims to estimate OC stocks in different pools(soil,organic horizons,and aboveground vegetation)and identify factors influencing these stocks in an alpine environment.We sampled 146 sites representing six forest types and two grassland types in the Gran Paradiso National Park(northern Italian Alps).Field samples of soils,organic horizons,and data on aboveground trees were collected to assess OC stocks,along with environmental variables.Our findings reveal nuanced variations in OC stocks across different ecosystem components.In grasslands,average soil OC was 5.57 kg m^(-2),while in forests it was 4.11 kg m^(-2).Organic horizons contained an average of 0.70 kg m^(-2),and aboveground vegetation in forests stored 6.61 kg m^(-2).Linear Mixed Models indicate that soil OC is influenced by habitat type,soil type,and elevation.OC in organic horizons is affected by aspect and forest habitat type,with composting further influenced by elevation.These results contribute to OC stock inventories for alpine ecosystems and enhance our understanding of how environmental factors influence carbon storage.Importantly,they underscore the need to consider soil type and other factors beyond land use when modeling OC stocks.This insight has implications for designing effective territorial strategies to address climate change,emphasizing the importance of a multifaceted approach to carbon stock assessment and management in alpine regions.
基金the National Natural Science Foundation of China(grant no.31971639)the Natural Science Foundation of Fujian Province(grant no.2023J01477)the Special Investigation on Science and Technology Infrastructure Resources(grant no.2019FY202108)for their support of this research。
文摘Vegetation resilience(VR),providing an objective measure of ecosystem health,has received considerable attention,however,there is still limited understanding of whether the dominant factors differ across different climate zones.We took the three national parks(Hainan Tropical Rainforest National Park,HTR;Wuyishan National Park,WYS;and Northeast Tiger and Leopard National Park,NTL)of China with less human interference as cases,which are distributed in different climatic zones,including tropical,subtropical and temperate monsoon climates,respectively.Then,we employed the probabilistic decay method to explore the spatio-temporal changes in the VR and their natural driving patterns using Geographically Weighted Regression(GWR)model as well.The results revealed that:(1)from 2000 to 2020,the Normalized Difference Vegetation Index(NDVI)of the three national parks fluctuated between 0.800 and 0.960,exhibiting an overall upward trend,with the mean NDVI of NTL(0.923)>HTR(0.899)>WYS(0.823);(2)the positive trend decay time of vegetation exceeded that of negative trend,indicating vegetation gradual recovery of the three national parks since 2012;(3)the VR of HTR was primarily influenced by elevation,aspect,average annual temperature change(AATC),and average annual precipitation change(AAPC);the WYS'VR was mainly affected by elevation,average annual precipitation(AAP),and AAPC;while the terrain factors(elevation and slope)were the main driving factors of VR in NTL;(4)among the main factors influencing the VR changes,the AAPC had the highest proportion in HTR(66.7%),and the AAP occupied the largest area proportion in WYS(80.4%).While in NTL,elevation served as the main driving factor for the VR,encompassing 64.2%of its area.Consequently,our findings indicated that precipitation factors were the main driving force for the VR changes in HTR and WYS national parks,while elevation was the main factors that drove the VR in NTL.Our research has promoted a deeper understanding of the driving mechanism behind the VR.
基金supported by the Central government subsidies to local public health special funds,National Key Research and Development Program of China[2022YFC2503101]Basic Research and Development Funds for Heilongjiang Province-affiliated Universities[2023-KYYWF-0272].
文摘Objective To analyze the epidemiological characteristics and epidemic situation of children with Kashin-Beck disease(KBD)in China,and provide the basis for formulating prevention and control measures.Methods Fixed-point monitoring,moving-point monitoring,and full coverage of monitoring were promoted successively from 1990 to 2023.Some children(7-12 years old)underwent clinical and right-hand X-ray examinations every year.According to the KBD diagnosis criteria,clinical and X-ray assessments were used to confirm the diagnosis.Results In 1990,the national KBD detectable rate was 21.01%.X-ray detection decreased to below 10%in 2003 and below 5%in 2007.Between 2010 and 2018,the prevalence of KBD in children was less than 0.4%,which fluctuated at a low level,and has decreased to 0%since 2019.Spatial epidemiological analysis indicated a spatial clustering of adult patients prevalence rate in the KBD areas.Conclusion The evaluation results of the elimination of KBD in China over the last 5 years showed that all villages in the monitored areas have reached the elimination standard.While the adult KBD patients still need for policy consideration and care.
基金This research was supported by the UBC APFNet Grant(Project ID:2022sp2 CAN).
文摘COVID-19 posed challenges for global tourism management.Changes in visitor temporal and spatial patterns and their associated determinants pre-and peri-pandemic in Canadian Rocky Mountain National Parks are analyzed.Data was collected through social media programming and analyzed using spatiotemporal analysis and a geographically weighted regression(GWR)model.Results highlight that COVID-19 significantly changed park visitation patterns.Visitors tended to explore more remote areas peri-pandemic.The GWR model also indicated distance to nearby trails was a significant influence on visitor density.Our results indicate that the pandemic influenced tourism temporal and spatial imbalance.This research presents a novel approach using combined social media big data which can be extended to the field of tourism management,and has important implications to manage visitor patterns and to allocate resources efficiently to satisfy multiple objectives of park management.
基金This work was jointly supported by the National Natural Science Foundation of China(Grant Nos.41975137,42175012,and 41475097)the National Key Research and Development Program(Grant No.2018YFF0300103).
文摘Since the Beijing 2022 Winter Olympics was the first Winter Olympics in history held in continental winter monsoon climate conditions across complex terrain areas,there is a deficiency of relevant research,operational techniques,and experience.This made providing meteorological services for this event particularly challenging.The China Meteorological Administration(CMA)Earth System Modeling and Prediction Centre,achieved breakthroughs in research on short-and medium-term deterministic and ensemble numerical predictions.Several key technologies crucial for precise winter weather services during the Winter Olympics were developed.A comprehensive framework,known as the Operational System for High-Precision Weather Forecasting for the Winter Olympics,was established.Some of these advancements represent the highest level of capabilities currently available in China.The meteorological service provided to the Beijing 2022 Games also exceeded previous Winter Olympic Games in both variety and quality.This included achievements such as the“100-meter level,minute level”downscaled spatiotemporal resolution and forecasts spanning 1 to 15 days.Around 30 new technologies and over 60 kinds of products that align with the requirements of the Winter Olympics Organizing Committee were developed,and many of these techniques have since been integrated into the CMA’s operational national forecasting systems.These accomplishments were facilitated by a dedicated weather forecasting and research initiative,in conjunction with the preexisting real-time operational forecasting systems of the CMA.This program represents one of the five subprograms of the WMO’s high-impact weather forecasting demonstration project(SMART2022),and continues to play an important role in their Regional Association(RA)II Research Development Project(Hangzhou RDP).Therefore,the research accomplishments and meteorological service experiences from this program will be carried forward into forthcoming highimpact weather forecasting activities.This article provides an overview and assessment of this program and the operational national forecasting systems.
文摘Objective:To describe the situation of measles in Sri Lanka from May to November,2023 and to define the role of virology laboratory towards case confirmation and epidemiological and genetic characterization of the outbreak.Methods:This retrospective study analyzed all samples tested for measles from 1st of May to 30th of November,2023 at National Measles Rubella Laboratory,Sri Lanka.According to the World Health Organization(WHO)algorithm,serum and oropharyngeal/nasopharyngeal swabs were tested with WHO recommended kits for anti-measles IgM and measles virus specific RNA,respectively.Selected RNA positive samples were sequenced at reference laboratory,India.Analysis of sequencing data and construction of phylogenetic tree were carried out at National Measles Rubella Laboratory.Data was analyzed using descriptive statistics.Results:Of the total 1132 serum samples and 497 oropharyngeal/nasopharyngeal swabs from 1326 patients,657(49.5%)patients were confirmed as measles by anti-measles IgM,measles virus specific RNA or both.Males(55.6%,n=365)and the age group from>20 to≤30 years(33.0%,n=217)predominated positive patients.All provinces reported measles positive cases.All samples sequenced(100%,n=42)were genotype D8 with 95.2%(n=40)bearing Victoria.Australia origin.Conclusions:We described resurgence of measles in an eliminated country,confirming the genotype to be D8,one of the two genotypes currently circulating globally.Further,the study strongly convinced the importance of a strengthened virological surveillance system in an eliminated country,despite its eliminated status.
文摘The National Natural Science Foundation of China is one of the major funding agencies for neuro rehabilitation research in China.This study reviews the frontier directions and achievements in the field of neurorehabilitation in China and wo rldwide.We used data from the Web of Science Core Collection(WoSCC) database to analyze the publications and data provided by the National Natural Science Foundation of China to analyze funding information.In addition,the prospects for neurorehabilitation research in China are discussed.From 2010 to 2022,a total of 74,220 publications in neurorehabilitation were identified,with there being an overall upward tendency.During this period,the National Natural Science Foundation of China has funded 476 research projects with a total funding of 192.38 million RMB to support neuro rehabilitation research in China.With the support of the National Natural Science Foundation of China,China has made some achievements in neurorehabilitation research.Research related to neurorehabilitation is believed to be making steady and significant progress in China.
基金The Fundamental Research Fund Project of the First Institute of OceanographyMinistry of Natural Resources+1 种基金under contract No.GY022Y07the National Natural Science Foundation of China under contract No.42106232。
文摘During the 10th Chinese Arctic scientific expedition carried out in the summer of 2019,the surface current in the high-latitude areas of the Arctic Ocean was observed using a self-developed surface drifting buoy,which was initially deployed in the Chukchi Sea.The buoy traversed the Chukchi Sea,Chukchi Abyssal Plain,Mendeleev Ridge,Makarov Basin,and Canada Basin over a period of 632 d.After returning to the Mendeleev Ridge,it continued to drift toward the pole.Overall,the track of the buoy reflected the characteristics of the transpolar drift and Chukchi Slope Current,as well as the inertial flow,cross-ridge surface flow,and even the surface disorganized flow for some time intervals.The results showed that:(1)the transpolar drift mainly occurs in the Chukchi Abyssal Plain,Mendeleev Ridge,and western Canada Basin to the east of the ridge where sea ice concentration is high,and the average northward flow velocity in the region between 79.41°N and 86.32°N was 5.1 cm/s;(2)the average surface velocity of the Chukchi Slope Current was 13.5 cm/s,and while this current moves westward along the continental slope,it also extends northwestward across the continental slope and flows to the deep sea;and(3)when sea ice concentration was less than 50%,the inertial flow was more significant(the maximum observed inertial flow was 26 cm/s,and the radius of the inertia circle was 3.6 km).