Capillarys 2 Flex Piercing糖化血红蛋白检测系统的综合评估

目的综合评估基于毛细管电泳法的Capillarys 2 Flex Piercing糖化血红蛋白（Hb A1c）检测系统。方法验证Capillarys 2 Flex Piercing Hb A1c检测系统的相关性、精密度和线性范围等基本性能指标,并采用干扰实验评价其抗干扰能力,项目包括胆红素（Bil）、甘油三酯（TG）、血红蛋白（Hb）、不稳定糖化血红蛋白（LA1c）、Hb F和广东地区常见的Hb变异体（Hb E、Hb J-Bangkok、Hb New York、Hb G-Taipei和Hb G-Coushatta）。采用Capillarys 2 Flex Piercing Hb A1c检测系统检测Hb A2,评价其与毛细管电泳法的相关性;采用Capillarys 2 Flex Piercing Hb A1c检测系统测定40份美国国家糖化血红蛋白标准化计划（NGSP）Hb A1c临床实验室认证样本,分析其与NGSP参考实验室结果的差异,验证正确度。结果 Capillarys 2 Flex Piercing Hb A1c检测系统与VariantⅡTurbo 2.0 Hb A1c分析仪的相关性良好（r=0.997,P=0.000）;总精密度[变异系数（CV）]〈2.00%;Hb A1c在3.8%~17.1%范围内呈线性;当Bil≤355μmol/L、TG≤25.3 mmol/L、Hb为28~182 g/L、LA1c为1.2%~7.8%、Hb F≤22.3%时不受干扰;能分离广东地区常见的Hb变异体（Hb E、Hb J-Bangkok、Hb New York、Hb G-Taipei和Hb G-Coushatta）。Capillarys 2 Flex Piercing Hb A1c检测系统检测Hb A2和毛细管电泳法相关性良好（r=0.993,P=0.000）;与NGSP参考实验室结果的偏差均〈6%。结论 Capillarys 2 Flex Piercing Hb A1c检测系统完全能满足临床需求,可同时提供Hb A2的结果用于地中海贫血的筛查,是一种多用途的Hb A1c检测系统。

Progressing under the Exploration:Piercing the Corporate Veil in China

In 2005,the Chinese Company Law was revised for the first time in statutory form introduced Piercing the Corporate Veil.The establishment of this article will benefit Chinese legal system to prevent misuse of company law risk,ensure the safety of transactions,safeguard the interests of the creditors,maintenance social and economic order,and to promote the healthy development of the socialist market economy.Nevertheless,as the abstraction of the provisions,lack of maneuverability,waiting in further refined standstill.

Hydrodynamic characteristics of the surface-piercing propellers for the planing craft

Demand for high-speed marine vehicles (HSMVs) is high among both commercial and naval users. It is the duty of the marine vessel's designer to provide a hull and propulsion system that diminishes drag, improves propulsive efficiency, increases safety and improves maneuverability. From the propulsor side, surface piercing propellers (SPPs) should improve performance. Unlike immersed propellers, behavior of the SPP is affected by depth of immersion, Weber number and shaft inclination angle. This paper uses a practical numerical method to predict the hydrodynamic characteristics of an SPP. The critical advance velocity ratio is derived using the Weber number and pitch ratio in the transition mode, then the potential based boundary element method (BEM) is used on the engaged surfaces. Two models of three and six-bladed SPPs (SPP-1 and SPP-2) were selected and some results are shown.

Wave Resistance Study of Wave piercing Catamarans

Present paper researches the theoretical method for calculating the wave resistance of wave piercing catamarans.As an example the wave resistance of a wave piercing csatamaran is calculated.The comparison among the theoretical calculation results,the model test results and the diagram evaluation results shows the efficiency of present theoretical method.At last the dependence wave resistance of wave piercing catamarans on some parameters is investigated based on the theoretical method.

Original Support of an after Piercing Lobular Keloid Scar: About a Case

Keloids are tissue repair formed by exuberant fibrosis appearing after a skin wound, burn, vaccination or post inflammatory (folliculitis or acne lesion). This condition causes standard aesthetic prejudice to those who are affected. Its management is difficult and its evolution meshes recurrences. We report here a case of giant keloid in the right ear lobe after a piercing and its support.

Effect of Three-High Rotary Piercing Process on Microstructure,Texture and Mechanical Properties of Magnesium Alloy Seamless Tube

Mg alloy seamless tubes(MASTs)were prepared through three-high rotary piercing process,effect of billet temperature,feed angle and plug advance on microstructure,texture and mechanical properties of tubes were investigated.The effect on the deformation mechanism and improving mechanical properties mechanism of this process for MASTs were studied.The results show that the grain size could be refined to 11.3-31.1%of the initial grain size and the microstructure was more uniform due to the accumulation of strain.The formation of high strain gradient at the grain boundary activated the non-basal slip.This piercing process could change the grain orientation of as-extruded billet and eliminate the initial basal texture to produce new favorable texture.And the process could accelerate the continuous dynamic recrystallization process.After piercing,yield strength of pierced tubes decreased by 6.7%,ultimate tensile strength(UTS)and elongation increased by 32.4 and 45%,respectively,at optimal parameters.The plate-shapedβ_(1)-Mg_(17)Al_(12) orientation transformed from basal plates to prismatic plates,facilitating the increase in UTS and ductility.The decrease size of nanoscale precipitates could reduce the cracking possibility.The critical resolved shear stress ratios of pyramidal(10−11)slip and(11−22)slip to basal slip for the sample including prismatic plates both decreased compared to that including basal plates.This could enhance the ductility of tube sample.Moreover,grain boundary sliding could contribute to a better ductility via coordinating deformation and reducing stress concentration during piercing process.

一类反三角算子矩阵的Zhou可逆性

文章研究了正交条件下反三角算子矩阵M=(A I B 0)的Zhou可逆性.由此获得了相关扰动算子矩阵的Zhou可逆性刻画,并给出了相关数值例子.

Constitutive Relationship of New Steel 33Mn2V and Its Application in Piercing Process by FEM Simulation

Based on test data from the hot forge experiments on Gleeble 1500, a Kumar type constitutive equation for 33Mn2V steel is established. Applying this constitutive equation in commercial FEM software of MSC/SuperForm 2005, the piercing process of 33Mn2V steel in Mannesmann mill is then simulated. The modeling results visualized the dynamic evolution of equivalent stress, especially inside the workpieee. It is shown that the non-uniform distribu- tion of stress on the internal and external surface of the workpiece is a distinct characteristic of processing tube pierc- ing. The numerical model was verified by comparing the values of calculated force parameters of the piercing process with those measured in laboratory eonditions. And it shows that the Kumar-type constitutive relationship meets the practical needs.

Modeling and Optimization for Piercing Energy Consumption

Energy consumption is an important quality index in the production of seamless tubes. The complex factors affecting energy consumption make it difficult to build its mechanism model, and optimization is also very difficult, if not impossible. The piercing process was divided into three parts based on the production process, and an energy consumption prediction model was proposed based on the step mean value staged multiway partial least square meth- od. On the basis of the batch process prediction model, a genetic algorithm was adopted to calculate the optimum mean value of each process parameter and the minimum piercing energy consumption. Simulation proves that the op- timization method based on the energy consumption prediction model can obtain the optimum process parameters effectively and also provide reliable evidences for practical production.

Development of Technology and Equipment for Non-destructive Testing of Defects in Sewing Mandrels of a Three-roll Screw Mill 30-80

The conditions of heating and cooling of piercing mandrels made of 4X5MFS steel of a three-roll screw mill 30-80 in the production of a closed cavity of steel vessels of small volume are determined.It is established that multiple cycles of heating up to 600℃ and cooling with water up to 80℃ for about 7 seconds/1 cycle lead to the formation of ridges,shells and cracks on the surface and in the volume of the tool.The loss of structural strength of the material leads to the breakdown of the mandrel during the stitching process.The technique and equipment of magnetic powder control have been developed to establish the dynamics of the growth of internal and external defects of mandrels.An equation is obtained that allows determining the increase in the number of defects in the sewing tool of a screw rolling mill.The technology of non-destructive testing made it possible to develop a rational plan for replacing the sewing mandrels,which allows for predicting the appearance of defects leading to a complex breakdown of the deforming tool at the NPO Pribor machine-building enterprise.

算子矩阵Zhou逆的几个新结果

文章研究Banach空间上算子矩阵的Zhou逆问题,证明了一定条件下线性算子差的Zhou可逆性,并将所得结果应用到算子矩阵上,获得了相关算子矩阵的Zhou可逆性.

STUDY ON EFP PENETRATION SIMULATION LAW

This paper analyses the geometrical analogue rules of explosively formed projectile (EFP) penetrating armours with the help of similarity theory, and establishes EFP penetrating armour simulation law. Based on the simulation law established here, prototype experiments and model experiments with the simulation ratio of 1.33 are designed, and the penetrating armour experiments with 45 # carbon steel plates are separately conducted. By means of data processing of experimental results, it is concluded that EFP penetrating armour simulation law established is tenable.

纬编针织物在计算机中的三维仿真

为真实模拟纬编针织物的结构,通过分析纬编针织物的物理模型,在三维Pierce线圈模型基础上,引入B样条及椭圆描述线圈,从而建立三维几何线圈模型.根据纱线线圈的中心线走向,将线圈分为两个部分:弧段和圈柱,弧段(如针编弧、沉降弧)用椭圆描述,圈柱用三次B样条曲线模拟.最后利用OpenGL结合VC++模拟针织物的结构,并实现光照效果.试验结果表明:采用该模型及实现方法,模拟效果比单独采用三维Pierce模型、B样条模型更加逼真.

一种低功耗高稳定性晶体振荡器芯片的设计

分析了传统Pierce振荡器不足,提出了改进型的振荡器结构,并基于0.35μm CMOS工艺,设计实现了一款低功耗高稳定性的晶体振荡器芯片.芯片有两种工作模式:正常工作模式和低功耗模式.测试结果表明,在电源电压为5 V、振荡频率为30 MHz、负载电容15 pF时,芯片消耗总电流低于5 mA,振荡电路消耗电流仅为0.6 mA,输出占空比为50±0.8%的方波信号,其频率随电源电压的变化率仅为0.5×10-6.引入低功耗模式,振荡器消耗电流降低至3μA以下,和传统结构相比,功耗降低了60%,频率随电压稳定性提高了10倍.

FE SIMULATION OF CENTER CRACK OCCURRENCE IN TUBE ROUNDS DURING TWO-ROLL ROTARY ROLLING PROCESS

With the aid of FE （finite element） code MSC.Superform 2005, 2-D coupled thermo-mechanical simulation of center-crack occurrence in round billet during 2-roll rotary rolling process was presented using Oyane ductile fracture criteria. A simple modeling is put forward based on the spiral motion of the workpiece as an essential characteristic in movement. The influence of the feed angle and the entry cone angle of the main roll on the process was taken into account in the modeling. The soundness for simplifying the 3-D rotary rolling into a 2-D problem was discussed. By adopting the parameters of Diescher piercer in 140mm mandrel mill of Bao Steel, the distribution and development of strain/stress were analyzed, and the eigen value of ductile fracture as well. The critical percentage of diameter reduction was obtained from the simulation. The result showed a good agreement with the experimental value, and therefore was of widely guiding significance to the practical process for rationally formulating the deformation parameters of steel tube piercing.

一种单片高稳振荡器芯片设计

针对传统Pierce振荡器改进了振荡器的起振电路结构,采用负阻起振理论基于0.35μm CMOS工艺设计了一种单片高稳振荡器芯片。芯片主要包含起振电路、缓冲器电路、驱动电路、使能电路及分频器电路,输出频率范围为4 MHz^30 MHz可调,应用cohesion及Hspice软件完成了电路设计与仿真,使用Cadence软件进行了芯片的版图设计,LVS验证后完成了芯片的后仿真工作,仿真结果表明在设定的6种晶体参数下,电路在800μs时完成了起振且在tt、ff、ss 3种模式下输出平稳,该芯片能适用于无线收发信机中。

Processing Map of C71500 Copper-nickel Alloy and Application in Production Practice

The isothermal compression tests of C71500 copper-nickel alloy at different temperatures (1 073-1 273 K) and strain rates (0.01-10 s^-1) were carried out on Gleeble-3500 thermo-mechanical simulator.The real stress-strain data were obtained.On the basis of dynamic material model,the power dissipation was established.The peak efficiency of the power dissipation is 57%.At the same time,Prasad’s,Murty’s and Babu’s instability criteria based on Ziegler’s expectant rheology theory,and Gegel’s and Malas’s instability criteria based on Lyaponov’s function theory,were used to predict the unstable regions in the processing map.The maximum entropy generation rate and large plastic deformation principle are more in line with the hot deformation process of C71500 alloy,so the accuracy of Prasad’s instability criterion is much better.According to the obtained macro-crack and micro-metallographic structure morphologies,the temperature range of 1 098-1 156 K and the strain rate range of 2.91-10 s^-1,and the temperature range of 1 171-1 273 K and the strain rate range of 0.01-0.33 s^-1 are more suitable for the processing area of C71500 alloy.The accuracy of the above conclusions were verified by the forging of materials and the analysis of hot piercing tubes.The significance of this paper is to provide theoretical basis and technological conditions for hot-press processing of C71500 alloy.

Failure investigation on high velocity impact deformation of boron carbide(B_(4)C) reinforced fiber metal laminates of titanium/glass fiber reinforced polymer

High velocity ballistic impact deformation behaviour of Titanium/GFRP Fiber Metal Laminates(FML)has been explored.Both single and multiple projectiles impact conditions were considered.Ti/GFRP FML targets were fabricated with addition of 5%and 10%weight percentage of boron carbide(B_(4)C)particles.Mechanical properties of Ti/GFRP FML targets were determined as per ASTM standards.High velocity ballistic experiments were conducted using Armour Piercing Projectile(APP)of diameter 7.62 mm and velocity ranging between 350 and 450 m/s.Depth of penetration of the projectile into the target was measured.The deformation behaviour of Ti/GFRP targets with and without the presence of ceramic powder(B_(4)C)was investigated.“Ductile hole growth”failure mode was observed for pure GFRP target when subjected to single projectile impact whereas“plugging”failure mode was noted for Ti/GFRP targets.The presence of B_(4)C(5%by weight)particles has significantly improved the ballistic resistance of the Ti/GFRP FML target by offering frictional resistance to the projectile penetration.Further addition(10%by weight)of B_(4)C has reduced the ballistic performance due to agglomeration.None of the targets showed‘brittle cracking’or‘fragmentation’failures.When compared to the published results of Aluminium(Al 1100/GFRP and Al 6061/GFRP)FMLs,Ti/GFRP FML showed lesser DoP which increases its potential application to aerospace industry.

Resistance of grid steel-tube-confined concrete targets against projectile impact: Experimental investigation and analytical engineering model

Steel-tube-confined concrete(STCC) targets are provided with excellent anti-penetration performance over semi-infinite concrete(SIC) targets since the steel tube imposes passive restraint on the in-filled concrete during the penetration process. Grid STCC system with square steel tubes is a potential solution to protective structures. In this paper, experiments of 9-cell grid STCC targets penetrated by 12.7 mm Armor Piercing Projectile(APP) were performed. The influence of side length and thickness of steel tube,steel ratio and impact velocity on anti-penetration performance were taken into account. Additionally,single-cell square STCC targets were also designed and tested for comparison with the 9-cell grid STCC targets. Damage modes and parameters of the tested targets were measured and discussed. Moreover,the stiffness of radial confinement of grid STCC targets is achieved according to the elastic solution of infinite cylindrical shell in Winkler medium. Furthermore, the penetration resistance and depth of penetration(DOP) for grid STCC targets are obtained on the basis of the dynamic finite spherical cavityexpansion(FSCE) models including radial confinement effect. It is shown that the 9-cell grid STCC targets with optimal dimension match of thickness and side length of steel tube can reduce the DOP by about17 % and 23 % in comparison with the SIC targets and single-cell square STCC targets, respectively, due to both the confinement of square steel tube to concrete in the impacted cell and the additional confinement of the surrounding cells to the impacted cell;the penetration resistance and DOP of the grid and cellular STCC targets with similar steel ratio is close, and thus the grid STCC targets with simpler manufacturing process and excellent in-plane expandability are preferred in engineering practice;moreover, the predicted results of DOP model based on the FSCE models agree well with the tested results with the maximum disparity less than 12 % and the proposed model is more applicable to the grid and cellular STCC targets with high radial confinement.

Quality prediction and control of tube hollow

The quality prediction of tube hollow model based on the variance staged multiway partial least square (MPLS) method was proposed.The key aspects of staged decomposition of the productive data,calculation of the variance value,modeling,and on-lined prediction in the variance-staged MPLS method were introduced.Based on the model,iterative optimal control method was used for quality control of tube hollow.The experimental results show that the obvious benefits of this method are low maintenance cost,good real time function,high reliability precision,and practical application to on-line prediction and optimization on the quality of tube hollow.