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Effects of Feixinning Capsules on BODE Index,CRP and Quality of Life in AECOPD Patients with Right Heart Failure
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作者 Yiqi WEN Ruifen ZHANG He SU 《Medicinal Plant》 CAS 2021年第5期71-74,共4页
[Objectives]To investigate the therapeutic effect of Feixinning Capsules on acute exacerbation of chronic obstructive pulmonary disease(AECOPD)complicated with right heart failure.[Methods]A total of 60 cases of AECOP... [Objectives]To investigate the therapeutic effect of Feixinning Capsules on acute exacerbation of chronic obstructive pulmonary disease(AECOPD)complicated with right heart failure.[Methods]A total of 60 cases of AECOPD patients with right heart failure and phlegm-heat syndrome were randomly selected as the study subjects,and were divided into the Feixinning group(n=30)and the control group(n=30).The Feixinning group was treated with Feixinning Capsules combined with conventional western medicine,and the control group was treated with conventional western medicine.The pulmonary function,CRP,CAT score,BODE index item index,and EQ-5D index were compared between the two groups before and after treatment.[Results]After treatment,the pulmonary function,CRP,CAT score,6MWD,mMRC,BODE score and EQ-5D index in the Feixinning group were significantly improved compared with the control group(P<0.05),and there was no statistical difference in the change of BMI index(P>0.05).[Conclusions]Feixinning Capsules can effectively improve the clinical symptoms and quality of life of patients with AECOPD complicated with right heart failure and phlegm-heat syndrome. 展开更多
关键词 AECOPD right heart failure Phlegm-heat syndrome Feixinning Capsules BODE index EQ-5d index
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Right Heart Failure Indicative of Ebstein’s Disease in Adulthood about a Case
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作者 Sana Samoura Alpha Koné +8 位作者 Ibrahima Sory 2 Sylla Mamadou Bachir Bah Morlaye Soumaoro Aly Samoura Aboulaye Camara Ibrahima Sory Barry Elhadj Yaya Balde Mariama Beavogui Mamadou Dadhi Balde 《World Journal of Cardiovascular Diseases》 2023年第9期613-618,共6页
Ebstein disease is a rare congenital malformation whose clinical presentation differs according to the anatomical form and age of the patient. In adults, it presents mainly in the form of right or global heart failure... Ebstein disease is a rare congenital malformation whose clinical presentation differs according to the anatomical form and age of the patient. In adults, it presents mainly in the form of right or global heart failure or rhythm disorders. Survival is exceptionally long in some forms. We report the case of a 70-year-old patient with Ebstein’s disease in right heart failure. 展开更多
关键词 Ebstein’s Disease right heart failure
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Relationship between lipidslevelsand right ventricular volume overload in congestive heart failure 被引量:3
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作者 Ying CHEN Xiao-Mei HE +11 位作者 Hong MENG Qing-Zhen ZHAO Yu-Zhi ZHEN Li TIAN Le WANG Li-Shuang JI Guo-Ping MA Yu TIAN Gang LIU Zhen-Guo JI Kun-Shen LIU Chao LIU 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2014年第3期192-199,共8页
BackgroundThe relationship between lipids and coronary artery disease has been well established. However, this is not the case between lipids and heart failure. Ironically, high lipid levels are associated with better... BackgroundThe relationship between lipids and coronary artery disease has been well established. However, this is not the case between lipids and heart failure. Ironically, high lipid levels are associated with better outcomes in heart failure, but the mechan-isms underlying the phenomenon are not fully understood. This study was performed to test the hypothesis that reduced intestinal lipid absorption due to venous congestion may lead to low lipid levels.MethodsWe collected data of clinical characteristics, echocardio-graph, and lipid profile in 442 unselected patients with congestive heart failure. Correlations between lipid levels[including total cho-lesterol(TCL), high-density lipoprotein cholesterol(HDL-C), low-density lipoprotein cholesterol(LDL-C), and triglycerides(TG)]and right ventricle end diastolic diameter (RVEDD), left ventricle end diastolic diameter (LVEDD), right atrium diameter (RA), left atrium diameter (LA), or left ventricle ejection fraction (LVEF) were analyzed using Pearson correlation and partial correlation. RVEDD, LVEDD, RA, and LA were indexed to the body surface area.ResultsThere was a significantly inverse correlation between TCL le-vels and RVEDD (r=-0.34,P〈0.001) and RA (r=-0.36,P〈0.001). Other lipids such as LDL-C, HDL-C, and TG had asimilar inverse correlation with RVEDD and RA. All these correlations remained unchanged after adjusting for age, gender, smoking status, physical activity levels, comorbidities, and medication use.ConclusionsLipid levels were inversely correlated to RVEDD in patients with congestive heart failure; however, because this was an observational study, further investigation is needed to verify our results as wellas identify a causal relationship, if any. 展开更多
关键词 Lipid levels heart failure right ventricle Volume overload Correlation analysis
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Establishment of adult right ventricle failure in ovine using a graded, animal-specific pulmonary artery constriction model 被引量:1
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作者 Michael Nguyen-Truong Wenqiang Liu +4 位作者 June Boon Brad Nelson Jeremiah Easley Eric Monnet Zhijie Wang 《Animal Models and Experimental Medicine》 CSCD 2020年第2期182-192,共11页
Background: Right ventricle failure(RVF) is associated with serious cardiac and pulmonary diseases that contribute significantly to the morbidity and mortality of patients. Currently, the mechanisms of RVF are not ful... Background: Right ventricle failure(RVF) is associated with serious cardiac and pulmonary diseases that contribute significantly to the morbidity and mortality of patients. Currently, the mechanisms of RVF are not fully understood and it is partly due to the lack of large animal models in adult RVF. In this study, we aim to establish a model of RVF in adult ovine and examine the structure and function relations in the RV.Methods: RV pressure overload was induced in adult male sheep by revised pulmonary artery constriction(PAC). Briefly, an adjustable hydraulic occluder was placed around the main pulmonary artery trunk. Then, repeated saline injection was performed at weeks 0, 1, and 4, where the amount of saline was determined in an animal-specific manner. Healthy, age-matched male sheep were used as additional controls. Echocardiography was performed bi-weekly and on week 11 post-PAC, hemodynamic and biological measurements were obtained.Results: This PAC methodology resulted in a marked increase in RV systolic pressure and decreases in stroke volume and tricuspid annular plane systolic excursion, indicating signs of RVF. Significant increases in RV chamber size, wall thickness, and Fulton's index were observed. Cardiomyocyte hypertrophy and collagen accumulation(particularly type III collagen) were evident, and these structural changes were correlated with RV dysfunction.Conclusion: In summary, the animal-specific, repeated PAC provided a robust approach to induce adult RVF, and this ovine model will offer a useful tool to study the progression and treatment of adult RVF that is translatable to human diseases. 展开更多
关键词 animal models FIBROSIS pulmonary artery banding pulmonary hypertension right heart failure
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Twin pregnancy with sudden heart failure and pulmonary hypertension after atrial septal defect repair: A case report
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作者 Chun-Xiao Tong Tao Meng 《World Journal of Clinical Cases》 SCIE 2023年第35期8350-8356,共7页
BACKGROUND Pulmonary arterial hypertension(PAH)in pregnancy is one of the major obstetric complications and is considered a contraindication to pregnancy as it is classified as a class IV risk in the revised risk clas... BACKGROUND Pulmonary arterial hypertension(PAH)in pregnancy is one of the major obstetric complications and is considered a contraindication to pregnancy as it is classified as a class IV risk in the revised risk classification of pregnancy by the World Health Organisation.Pregnancy,with its adaptive and expectant mechanical and hormonal changes,negatively affects the cardiopulmonary circulation in pregnant women.Do patients with repaired simple congenital heart disease(CHD)develop other pulmonary and cardiac complications during pregnancy?Can pregnant women with sudden pulmonary hypertension be treated and managed in time?In this paper,we present a case of a 39-year-old woman who underwent cesarean section at 33 wk'gestation and developed PAH secondary to repaired simple CHD.Our research began by a PubMed search for"pulmonary hypertension"and"pregnancy"and"CHD"case reports.Three cases were selected to review PAH in pregnancy after correction of CHD defects.These studies were reviewed,coupled with our own clinical experience.CASE SUMMARY Herein,a case involving a woman who underwent atrial septal defect repair at the age of 34,became pregnant five years later,and had a sudden onset of PAH and right heart failure secondary to symptoms of acute peripheral edema in the third trimester of her pregnancy.As a result,the patient underwent a cesarean section and gave birth to healthy twins.Within three days after cesarean delivery,her cardiac function deteriorated as the pulmonary artery pressure increased.Effec-tive postpartum management,including diuresis,significant oxygen uptake,vasodilators,capacity and anticoagulants management,led to improvements in cardiac function and oxygenation.The patient was discharged from hospital with a stable recovery and transferred to local hospitals for further PAH treatment.CONCLUSION This case served as a reminder to obstetricians of the importance of pregnancy after repair of CHD.It is crucial for patients with CHD to receive early correction.It suggests doctors should not ignore edema of twin pregnancy.Also,it provides a reference for the further standardization of antenatal,in-trapartum and postpartum management for patients with CHD worldwide. 展开更多
关键词 Congenital heart defects Pulmonary hypertension right heart failure Twin pregnancy Perioperative management Case report
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Outcomes of Ebstein's Anomaly Patients Treated with Tricuspid Valvuloplasty or Tricuspid Valve Replacement:Experience of a Single Center 被引量:1
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作者 Bin Li Han-Song Sun +1 位作者 Shi-Wei Pan Jian-Ping Xu 《Chinese Medical Journal》 SCIE CAS CSCD 2018年第9期1067-1074,共8页
Background:The incidence of Ebstein's anomaly is extremely low,and except for the Mayo Clinic,no cardiac center has reported on a sufficient number of patients.The aim of our study was to report the outcomes of Ebst... Background:The incidence of Ebstein's anomaly is extremely low,and except for the Mayo Clinic,no cardiac center has reported on a sufficient number of patients.The aim of our study was to report the outcomes of Ebstein's anomaly patients treated with tricuspid valvuloplasty (TVP) or tricuspid valve replacement (TVR).Methods:TVP or TV R was performed in 245 patients from July 2006 to April 2016.We reviewed patients' records and contacted patients via outpatient service and over the telephone.Results:The mean follow-up time was 43.6 ± 32.6 months,and 224 (91.4%) patients underwent follow-up.The mean operative age was 31.2 ± 15.7 years.TVR was performed in 23 patients,and TVP was performed in 201 patients.The 30-day mortality rate was 1.3%,and the overall survival rate was 97.9% at 5 and l0 years.The early mortality rate of the TVP group was lower than that of the TVR group (0.5% vs.8.7%,P =0.028),and the overall mortality rate of the TVP group was lower than that of the TVR group,without statistical significance (1.0% vs.8.7%).After propensity score matching,the rates of mortality and New York Heart Association class ≥Ⅲ were lower in the TVP group than those in the TVR group without statistical significance.Seven patients with Type B Wolff-Parkinson-White (WPW) syndrome underwent one-stage surgery,and arrhythmias disappeared.Six patients suffered from episodes of left ventricular outflow tract obstruction (LVOTO) during surgery.Severe LVOTO could be treated with reoperation of the atrialized right ventricle.Conclusions:Ebstein's anomaly patients treated with TVP or TVR can experience optimal outcomes with midterm follow-up.However,TVP should be the first-choice treatment.Optimal outcomes can be obtained from one-stage operation in patients with Type B WPW syndrome.Severe LVOTO during surgery might be related to improper operation of the atrialized right ventricle. 展开更多
关键词 Congenital heart Disease right heart failure Tricuspid Regurgitation Tricuspid Valve Dysplasia
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