Study on oxidizing cellulose to 2.3-dialdehyde cellulose by sodium periodate （NalO4） was carried out. The effects of reaction conditions such as pH of solution, temperature, oxidant concentration, oxidation time. th...Study on oxidizing cellulose to 2.3-dialdehyde cellulose by sodium periodate （NalO4） was carried out. The effects of reaction conditions such as pH of solution, temperature, oxidant concentration, oxidation time. the particle size of 2,3-dialdehyde cellulose and alkali treatment temperature on the dialdehyde concentration ot cellulose were investigated in detail, The results show that the aldehyde group content was created while reaction temperature and alkali treatment temperature increased. The most principal factors affecting the aldehyde group content of 2,3-dialdehyde cellulose were found out and the best oxidation conditions were as follows： the pH was 2. the reaction temperature was 45℃. the mass ratio of cellulose to NalO4 was 1/2, the reaction time was 4 h, the alkali treatment temperature was 70℃ and smaller particle size was 0.80 mm.展开更多
The effect of some nitrogen bases on the oxygenation of tetralin by sodium periodate, catalyzed by Mn（TPP）OAc, was evaluated. A series of eight bases, including imidazole, pyridine, and quinuclidine, was used. Bindi...The effect of some nitrogen bases on the oxygenation of tetralin by sodium periodate, catalyzed by Mn（TPP）OAc, was evaluated. A series of eight bases, including imidazole, pyridine, and quinuclidine, was used. Binding of axial ligand to the four-coordinate Mn（Ⅲ）-center influenced the efficiency and selectivity of the catalytic oxygenation system.展开更多
The use of natural polysaccharide crosslinkers for decellularized matrices is an effective approach to prepare cardiovascular substitute materials.In this research,NalO_(4)was applied to oxidize konjac glucomannan to ...The use of natural polysaccharide crosslinkers for decellularized matrices is an effective approach to prepare cardiovascular substitute materials.In this research,NalO_(4)was applied to oxidize konjac glucomannan to prepare the polysaccharide crosslinker oxidized konjac glucomannan(OKGM).The as-prepared crosslinker was then used to stabilize collagen-rich decellularized porcine peritoneum(DPP)to construct a cardiovascular substitute material(OKGM-fixed DPP).The results demonstrated that compared with GA-fixed DPP and GNP-fixed DPP,3.75%OKGM[1∶1.5(KGM∶NalO_(4))]-fixed DPP demonstrated suitable mechanical properties,as well as good hemocompatibility,excellent anti-calcification capability,and anti-enzymolysis in vitro.Furthermore,3.75%OKGM[1∶1.5(KGM∶NalO_(4))]-fixed DPP was suitable for vascular endothelial cell adhesion and rapid proliferation,and a single layer of endothelial cells was formed on the fifth day of culture.The in vivo experimental results also showed excellent histocompatibility.The current results demonstrted that OKGM was a novel polysaccharide cross-linking reagent for crosslinking natural tissues featured with rich collagen content,and 3.75%OKGM[1∶1.5(KGM∶NalO_(4))]-fixed DPP was a potential cardiovascular substitute material.展开更多
基金Supported by Natural Science Foundation of Tianjin (No. 03380211, 043610611).
文摘Study on oxidizing cellulose to 2.3-dialdehyde cellulose by sodium periodate （NalO4） was carried out. The effects of reaction conditions such as pH of solution, temperature, oxidant concentration, oxidation time. the particle size of 2,3-dialdehyde cellulose and alkali treatment temperature on the dialdehyde concentration ot cellulose were investigated in detail, The results show that the aldehyde group content was created while reaction temperature and alkali treatment temperature increased. The most principal factors affecting the aldehyde group content of 2,3-dialdehyde cellulose were found out and the best oxidation conditions were as follows： the pH was 2. the reaction temperature was 45℃. the mass ratio of cellulose to NalO4 was 1/2, the reaction time was 4 h, the alkali treatment temperature was 70℃ and smaller particle size was 0.80 mm.
文摘The effect of some nitrogen bases on the oxygenation of tetralin by sodium periodate, catalyzed by Mn（TPP）OAc, was evaluated. A series of eight bases, including imidazole, pyridine, and quinuclidine, was used. Binding of axial ligand to the four-coordinate Mn（Ⅲ）-center influenced the efficiency and selectivity of the catalytic oxygenation system.
基金supported by National Key Research and Development Program of China[Nos.2016YFC1100900,2016YFC1100901,2016YFC1100903 and 2016YFC1100904]"From 0 to 1"innovative research projects of Sichuan University(2022SCUH0045)The Key Research and Development Program of Sichuan Province(2020YFS0278).
文摘The use of natural polysaccharide crosslinkers for decellularized matrices is an effective approach to prepare cardiovascular substitute materials.In this research,NalO_(4)was applied to oxidize konjac glucomannan to prepare the polysaccharide crosslinker oxidized konjac glucomannan(OKGM).The as-prepared crosslinker was then used to stabilize collagen-rich decellularized porcine peritoneum(DPP)to construct a cardiovascular substitute material(OKGM-fixed DPP).The results demonstrated that compared with GA-fixed DPP and GNP-fixed DPP,3.75%OKGM[1∶1.5(KGM∶NalO_(4))]-fixed DPP demonstrated suitable mechanical properties,as well as good hemocompatibility,excellent anti-calcification capability,and anti-enzymolysis in vitro.Furthermore,3.75%OKGM[1∶1.5(KGM∶NalO_(4))]-fixed DPP was suitable for vascular endothelial cell adhesion and rapid proliferation,and a single layer of endothelial cells was formed on the fifth day of culture.The in vivo experimental results also showed excellent histocompatibility.The current results demonstrted that OKGM was a novel polysaccharide cross-linking reagent for crosslinking natural tissues featured with rich collagen content,and 3.75%OKGM[1∶1.5(KGM∶NalO_(4))]-fixed DPP was a potential cardiovascular substitute material.
