A novel algorithm using multiple spherical arrays based on spherical harmonic analysis is proposed to localize wideband acoustic sources. In the novel spherical harmonic algorithm, the re- ceived microphone signals ar...A novel algorithm using multiple spherical arrays based on spherical harmonic analysis is proposed to localize wideband acoustic sources. In the novel spherical harmonic algorithm, the re- ceived microphone signals are firstly used to do the spherical Fourier transformation. Then, the mul- tiple signal classification (MUSIC) algorithm is applied to the spherical components to obtain the an- gular-spectrum. Finally, the angular-spectrum smoothing technique is proposed to obtain the accu- rate localization of wideband sources. In contrast to the traditional single spherical array, the multi- pie spherical arrays used in this paper consist of several randomly distributed spheres in a given plane. The microphones are uniformly placed on each sphere, the same as the usual single spherical array. Simulation comparison of wideband sources localization between a single spherical array and multiple spherical arrays based on the novel algorithm is carried out to validate our proposed meth- od.展开更多
Two-dimensional(2D)layered materials with layer-number dependent properties are promising candidates for next-generation noble-metal-free electrocatalytic reaction.However,the main group metal chalcogenides(MMCs)used ...Two-dimensional(2D)layered materials with layer-number dependent properties are promising candidates for next-generation noble-metal-free electrocatalytic reaction.However,the main group metal chalcogenides(MMCs)used for this purpose are rarely explored.Herein,we report the controlled growth of indium selenide(In Se)with a novel morphology(semispherical array)on a silicon substrate and its application in hydrogen evolution reaction(HER).The formation of the spherical InSe is explained with a vapor-liquid-solid growth mechanism,in which the distribution and size of the spheres could be facilely tuned by the reaction parameters.The InSe semispherical array was demonstrated as more efficient catalyst for HER than the flake-like 2D InSe counterparts,originating from the fully exposed InSe spherical surface with abundant adsorbing sites and the high crystalline quality for electron transport.This work provides a controlled synthesis way of the layered In Se with a distinct spherical morphology used for the electrocatalysis applications and could be extended to other main group metal chalcogenides.展开更多
Under some circumstances surgical resection is feasible in a low percentage for the treatment of deep tumors. Nevertheless, high-intensity focused ultrasound (HIFU) is beginning to offer a potential noninvasive alte...Under some circumstances surgical resection is feasible in a low percentage for the treatment of deep tumors. Nevertheless, high-intensity focused ultrasound (HIFU) is beginning to offer a potential noninvasive alternative to conventional therapies for the treatment of deep tumors. In our previous study, a large scale spherical HIFU-phased array was developed to ablate deep tumors. In the current study, taking into account the required focal depth and maximum acoustic power output, 90 identical circular PZT-8 elements (diameter=1.4 cm and frequency=l MHz) were mounted on a spherical shell with a radius of curvature of 18 cm and a diameter of 21 cm. With the developed array, computer simulations and ex vivo experiments were carried out. The simulation results theoretically demonstrate the ability of the array to focus and steer in the specified volume (a 2 cm×2 cm×3 cm volume) at the focal depth of 15 to 18 cm. Ex vivo experiment results also verify the capability of the developed array to ablate deep target tissue by either moving single focal point or generating multiple foci simultaneously.展开更多
High-intensity focused ultrasound (HIFU) has attracted increasing interests as a promising noninvasive modality for the treatment of deep tumors in the thoracic and abdominal cavity.A 90-element HIFU spherical phased ...High-intensity focused ultrasound (HIFU) has attracted increasing interests as a promising noninvasive modality for the treatment of deep tumors in the thoracic and abdominal cavity.A 90-element HIFU spherical phased array applicator operated at 1 MHz has been developed for deep tissue ablation.The spherical array with a 5 cm wide central hole has a 21 cm diameter and an 18 cm radius of curvature.Annular element distribution with unequal element spacing is used to reduce the number of elements.The array is constructed with piezoelectric lead zirconate titanate (PZT-8) circular elements that are 1.4 cm in diameter and have a wall with thickness of 0.2 cm.The array offers an effective ablating depth of at least 8 cm in the tissue for both simulations and ex vivo experiments.The simulations demonstrate that the developed array can steer the focus with good quality of intensity distributions up to 6 mm off center over ranges from 17 to 21 cm when the water depth is set at 11 cm.We also present the beam focusing capability in deep tissue through a series of ex vivo experiments by measuring discoloration areas after sonications.These results indicate that the developed array is ideal for the ablation of deep-seated tissue.展开更多
文摘A novel algorithm using multiple spherical arrays based on spherical harmonic analysis is proposed to localize wideband acoustic sources. In the novel spherical harmonic algorithm, the re- ceived microphone signals are firstly used to do the spherical Fourier transformation. Then, the mul- tiple signal classification (MUSIC) algorithm is applied to the spherical components to obtain the an- gular-spectrum. Finally, the angular-spectrum smoothing technique is proposed to obtain the accu- rate localization of wideband sources. In contrast to the traditional single spherical array, the multi- pie spherical arrays used in this paper consist of several randomly distributed spheres in a given plane. The microphones are uniformly placed on each sphere, the same as the usual single spherical array. Simulation comparison of wideband sources localization between a single spherical array and multiple spherical arrays based on the novel algorithm is carried out to validate our proposed meth- od.
基金the financial support from the National key R&D Program of China(No.2021YFA1202802)Beijing Municipal Natural Science Foundation(No.1212016)+1 种基金National Natural Science Foundation of China(Nos.22104109 and 12102098)the CAS Pioneer Hundred Talents Program,and China Postdoctoral Science Foundation(Nos.2020M680479,2021M690801)。
文摘Two-dimensional(2D)layered materials with layer-number dependent properties are promising candidates for next-generation noble-metal-free electrocatalytic reaction.However,the main group metal chalcogenides(MMCs)used for this purpose are rarely explored.Herein,we report the controlled growth of indium selenide(In Se)with a novel morphology(semispherical array)on a silicon substrate and its application in hydrogen evolution reaction(HER).The formation of the spherical InSe is explained with a vapor-liquid-solid growth mechanism,in which the distribution and size of the spheres could be facilely tuned by the reaction parameters.The InSe semispherical array was demonstrated as more efficient catalyst for HER than the flake-like 2D InSe counterparts,originating from the fully exposed InSe spherical surface with abundant adsorbing sites and the high crystalline quality for electron transport.This work provides a controlled synthesis way of the layered In Se with a distinct spherical morphology used for the electrocatalysis applications and could be extended to other main group metal chalcogenides.
基金supported by the National Natural Science Foundation of China (No. 30800246)Shanghai Key Technologies R&D Programof China (No. 09441900500)
文摘Under some circumstances surgical resection is feasible in a low percentage for the treatment of deep tumors. Nevertheless, high-intensity focused ultrasound (HIFU) is beginning to offer a potential noninvasive alternative to conventional therapies for the treatment of deep tumors. In our previous study, a large scale spherical HIFU-phased array was developed to ablate deep tumors. In the current study, taking into account the required focal depth and maximum acoustic power output, 90 identical circular PZT-8 elements (diameter=1.4 cm and frequency=l MHz) were mounted on a spherical shell with a radius of curvature of 18 cm and a diameter of 21 cm. With the developed array, computer simulations and ex vivo experiments were carried out. The simulation results theoretically demonstrate the ability of the array to focus and steer in the specified volume (a 2 cm×2 cm×3 cm volume) at the focal depth of 15 to 18 cm. Ex vivo experiment results also verify the capability of the developed array to ablate deep target tissue by either moving single focal point or generating multiple foci simultaneously.
基金the National Natural Science Foundation of China(No. 30800246)the Shanghai Key Technologies R&D Program of China(No. 09441500900)the Med-X Shanghai Engineering Center Foundation(No. 08DZ2211201)
文摘High-intensity focused ultrasound (HIFU) has attracted increasing interests as a promising noninvasive modality for the treatment of deep tumors in the thoracic and abdominal cavity.A 90-element HIFU spherical phased array applicator operated at 1 MHz has been developed for deep tissue ablation.The spherical array with a 5 cm wide central hole has a 21 cm diameter and an 18 cm radius of curvature.Annular element distribution with unequal element spacing is used to reduce the number of elements.The array is constructed with piezoelectric lead zirconate titanate (PZT-8) circular elements that are 1.4 cm in diameter and have a wall with thickness of 0.2 cm.The array offers an effective ablating depth of at least 8 cm in the tissue for both simulations and ex vivo experiments.The simulations demonstrate that the developed array can steer the focus with good quality of intensity distributions up to 6 mm off center over ranges from 17 to 21 cm when the water depth is set at 11 cm.We also present the beam focusing capability in deep tissue through a series of ex vivo experiments by measuring discoloration areas after sonications.These results indicate that the developed array is ideal for the ablation of deep-seated tissue.