Effect of Health Management in Raising Awareness Rate of Disease Prevention and Treatment in Patients with Prehypertension

Objective: To analyze the effect of health management on improving the awareness rate of disease prevention and treatment in patients with prehypertension, so as to provide guidance for clinical management of patients with prehypertension. Methods: 108 patients diagnosed with prehypertension in our hospital were divided into a control group and an experimental group. The control group was not given management measures, while the experimental group was given health management. The incidence of hypertension and cognition level of hypertension knowledge were compared between the two groups after management. Results: The incidence of hypertension in the experimental group was 7.41% lower than that in the control group 29.63%. The cognitive level of hypertension in the patients (66.54 ± 1.25) was significantly higher than that in the patients without health management (41.45 ± 2.45), and P < 0.05;Conclusion: For patients with prehypertension, the implementation of health management is helpful to improve their cognition of hypertension, master related prevention knowledge, and reduce the incidence of hypertension.

Modeling the transmission dynamics of a time-delayed epidemic model with saturated treatment rate

In this paper,an attempt has been made to explore a new delayed epidemiological model assuming that the disease is transmitted among the susceptible population and possessing nonlinear incidence function along with a saturated treatment rate.Due attention is paid to the positivity and boundedness of the solutions and the bifurcation of the dynamical system as well.Basic reproduction number is being calculated,and considering the latent period as a bifurcation parameter,it has been examined that a Hopf-bifurcation occurs near the endemic equilibrium point while the parameter attains critical values.We have also discussed the stability and direction of Hopf-bifurcation near the endemic equilibrium point,the global stability analysis and the optimal control theory.We conclude that the system reveals chaotic dynamics through a specific time-delay value.Numerical simulations are being performed in order to explain the accuracy and effectiveness of the acquired theoretical results.

THERMAL RATE TREATMENT AND ITS EFFECT ON MODIFICATION OF Al-Si ALLOYS

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Arthroscopy Assisted Lesion Clearance and Bone Graft, Titanium Rod Support Treatment of Early Stage Osteonecrosis of the Femoral Head of the Postoperative Survival Rate Analysis

Objective: To assess the curative effect of the stage II femoral head necrosis treated by arthroscopy assisted lesion clearance, bone graft and titanium rod support. Methods: All the patients (including 58 patients 74 hips) were diagnosed as stage II femoral head necrosis according to the ARCO staging system during 2003-2013. In these patients, 15 hips were stage IIA, 34 hips were stage IIB and 25 hips were stage IIC. Located by C-arm and assisted by arthroscopy, minimally-invasive percutaneous pulp core decompression and lesion clearance within the femoral head were accurately performed, and then, the OAM composite of autologous bone marrow was implanted and the femoral head was supported using the titanium rod. Follow-up including the pain score, the Harris hip score and X-ray observation for disease progression were achieved at 6, 12, 24 and 36 months postoperatively, Kaplan-Meier survival curve was used for the survival analysis. Result: The VAS score and the Harris score after operation were better THRAn THRAt of before the surgery, the difference had statistical significance (p Conclusion: Arthroscopy assisted lesion clearance, bone graft and titanium rod support to treat the stage II osteonecrosis of the femoral head are effective and can prevent the femoral head from collapsing. But for stage IIC patients who had a history of the use of hormone, this surgery should be chosen carefully because the outcome is always very poor.

Treatment success rate of tuberculosis patients in Dabat, northwest Ethiopia

Evaluating the outcomes of DOTS program is essential for recognizing and amending system failures before the incidence and proportion of resistant isolates rise. In this study, we seek to evaluate the impact of DOTS strategy on tuberculosis treatment success rate in Dabat, northwest Ethiopia. Medical records of 1305 pulmonary and extrapulmonary tuberculosis patients registered from 2007 to 2012 at two health centers in Dabat district, northwest Ethiopia, were reviewed. Treatment outcomes and forms of tuberculosis were assessed according to WHO guidelines. Descriptive analyses were performed using frequencies and percentages. Treatment success rate was observed in 1146 (87.8%) patients. Out of these, 534 (89.1%) of the males and 612 (86.7%) of the females were successfully treated. It was also true in 338 (87.8%) of the smear-positive pulmonary tuberculosis patients, 473 (85.7%) of the smear-negative pulmonary tuberculosis patients, and 335 (91.0%) of the extrapulmonary tuberculosis patients. In conclusion, treatment success rate in the current study was slightly higher than the WHO international updated target for the period 2011 to 2015. However, this doesn’t mean that there will be no need for further enhancement of supervision and monitoring techniques, strengthening counseling and health education programs, and improving the quality of laboratory diagnostic services.

Greywater Treatment by High Rate Algal Pond under Sahelian Conditions for Reuse in Irrigation

High Rate Algal Pond (HRAP) was constructed and operated using a mixer device to investigate its capability in treating greywater for reuse in gardening. Physico-chemical and microbiological parameters were monitored. With a hydraulic retention time of 7.5 days and a solid retention time of 20 days, the average removal efficiencies (ARE) were 69% and 62% for BOD5 and COD respectively. The ARE for , and were 23%, 52% and 43% respectively. The removal of suspended solids (SS) was unsatisfactory, which could be attributed to the low average algal settling efficiencies of 9.3% and 16.0% achieved after 30 and 60 minutes respectively. The ARE of fecal coliforms, Escherichia coli and enterococci were 2.65, 3.14 and 3.17 log units respectively. In view of the results, the HRAP technology could be adapted for greywater treatment in sahelian regions. However, further studies on the diversity of the algal species growing in the HRAP unit are necessary in order to increase the removal of SS. Hazards of a reuse of the effluents are discussed on the basis of the various qualitative parameters. The residual content of E. coli was varying from 4 CFU per 100 mL. Based on WHO guidelines for greywater reuse in irrigation, the effluents could be used for restricted irrigation (E. coli < 105 CFU per 100 mL). Furthermore, the reuse potential is discussed on the basis of FAO guidelines using SAR (3.03 to 4.11), electrical conductivity (482 to 4500 μS/cm) and pH values (6.45 to 8.6).

Effect of surface treatment on the structure and high-rate dischargeability properties of AB_5-type hydrogen storage alloy

Surface-treated MmNi3.55Co0.75Mn0.4Al0.3 alloy as negative electrode material of nickel-metal hydride battery was employed to improve the high-rate dischargeability. Surface treatment was realized by dipping and stirring the alloy into a HCl aqueous solution with various concentrations at room temperature. The microstructure of the alloy before and after surface treatment was analyzed by X-ray diffraction （XRD） and scanning electron microscopy （SEM）. The electrochemical properties before and after surface treatment were compared, and the alloy treated in 0.025 mol/L HCl solution showed the optimal high-rate dischargeability.

Stability Analysis of an SIR Epidemic Model with Non-Linear Incidence Rate and Treatment

We consider a SIR epidemic model with saturated incidence rate and treatment. We show that if the basic reproduction number, R0 is less than unity and the disease free equilibrium is locally asymptotically stable. Moreover, we show that if R0 > 1, the endemic equilibrium is locally asymptotically stable. In the end, we give some numerical results to compare our model with existing model and to show the effect of the treatment term on the model.

Influence of hyperbaric oxygenation treatment (HBOT) on clinical outcomes (recurrent myocardial infarction and survival rate) during five-year monitoring period after acute myocardial infarction

Surgical treatments of acute myocardial infarction (MI) possess a high clinical effectiveness, but there are fixed limitations, related to the patient’s state, which are limited by medical resources and organizational problems. The development of new medical technologies provides a better and effective non-surgical treatment of acute MI and increases long-term prognosis in this category of patients. The study aims to investigate the influence of hyperbaric oxygenation treatment on clinical outcomes (survival rate and recurrent myocardial infarction (rMI)) during the five-year period of monitoring. The study involved 697 patients who suffered from acute MI, having undergone the standard treatment. The patients were randomly divided into two groups: Group 1 (reference, n = 363);Group 2 (test, n = 334). Patients of Group 2 were given the traditional treatment, accompanied with HBOT (isopression for forty minutes at a working pressure of 0.03 MPa). HBOT was applied first through the fifth day following MI. The treatment course included six cycles, once per day. The clinical assessment was focused on clinical outcome: rMI and mortality related to cardiovascular events. HBOT application that accompanied the acute MI with traditional pharmacotherapy has been proved to reduce rMI within five years following inpatient discharge (rMI rate was 14% in the reference group and 5.4% in the test group, χ2 = 13.3, р < 0.05). The combination of HBOT with traditional methods in treating acute MI makes it possible to raise the five-year survival rate from 84.4% up to 95.9%.

EFFECTS OF HEAT TREATMENT AND ENVIRONMENT ON CRACK PROPAGATION RATE IN STEEL GC-4 UNDER CORROSION FATIGUE AND STRESS CORROSION

Comparative investigations were carried out of the effect of heat treatment regimes Jor steel GC-4(40CrMnSiMoVA)on its crack propagating rates,from corrosion fatigue, (da/dN)_(CF),or stress corrosion cracking,(da/dt)_(SCC),in media with various constituents and pH values.Both(da/dN)_(CF) and(da/dt)_(SCC) accelerate with the increase of yield stress of the steel,yet the former is far less than the later.In comparison with media,the (da/dt)_(SCC) in distilled water is slightly greater than that in 3.5% NaCl solution,and the (da/dN)_(CF) in distilled water is far less than that in 3.5% NaCl solution.With the pH value increasing in 3.5% NaCl solution,the(da/dN)_(CF) lowers down and the(da/dt)_(SCC) speeds up.An explanation was also proposed with concept of the cyclic hardening and softening at crack tip,as well as the crack closure and occluded cell effect.

Influence of an External DC Electric Current on Plasma Cleaning Rate: an Application on the Enlarged Plasma-Surface Theor

During the last decades many researchers have been occupied with other plasma applications apart from the big challenge which the thermonuclear fusion poses. Many experiments have been carried out on the plasma behavior in contact with a solid surface; when the surface material consists of chemical compounds （e.g. oxides of metals）, then the plasma chemistry takes place. The present paper contains the final experimental and theoretical work of Plasma Laboratory at ＂Demokritos＂, which consists of an elaboration of plasma sheath parameters adapted to experimental conditions, a suitable choice of plasma gases （either H 2 or N 2 ）, and an electric po-tential current enforcement on objects. Additionally, a brief theory is given to explain the results, with a short reference to both boundary phenomena in thermonuclear reactors and low pressure plasma of glow discharges, so as to reveal the similarities and differences of these two cases. An extensive examination of the treated objects by X-ray diffraction method （XRD） gives results in agreement with the theoretical predictions. Using this improvement on plasma restoration system, （a combination of electric current on metallic object into suitable plasma）, it is shown that better results can be achieved on the cleaning and conservation of archaeological objects.

Screening on oil-decomposing microorganisms and application in organic waste treatment machine

As an oil-decomposable mixture of two bacteria strains(Bacillus sp. and Pseudomonas sp.), Y3 was isolated after 50 d domestication under the condition that oil was used as the limited carbon source. The decomposing rate by Y3 was higher than that by each separate individual strain, indicating a synergistic effect of the two bacteria. Under the conditions that T=25—40℃,pH=6—8, HRT(Hydraulic retention time)=36 h and the oil concentration at 0.1%, Y3 yielded the highest decomposing rate of 95.7 %. Y3 was also applied in an organic waste treatment machine and a certain rate of activated bacteria was put into the stuffing. A series of tests including humidity, pH, temperature, C/N rate and oil percentage of the stuffing were carried out to check the efficacy of oil-decomposition. Results showed that the oil content of the stuffing with inoculums was only half of that of the control. Furthermore, the bacteria were also beneficial to maintain the stability of the machine operating. Therefore, the bacteria mixture as well as the machines in this study could be very useful for waste treatment.

Efficacy of a therapeutic strategy for eradication of Helicobacter pylori infection

AIM: To determine the efficacy of our therapeutic strategy for Helicobacter pylori (H. pylori) eradication and to identify predictive factors for successful eradication. METHODS: From April 2006 to June 2010, we retrospectively assessed 2428 consecutive patients (1025 men, 1403 women; mean age 55 years, age range 18-92 years) with gastric histology positive for H. pylori infection referred to our unit for 13-C urea breath test(UBT), after first-line therapy with proton pump inhibitor (PPI) b.i.d. + amoxicillin 1 g b.i.d. + clarithromycin 500 mg b.i.d. for 7 d. Patients who were still positive to UBT were recommended a second-line therapy (PPI b.i.d. + amoxicillin 1 g b.i.d. + tinidazole 500 mg b.i.d. for 14 d). Third choice treatment was empirical with PPI b.i.d. + amoxicillin 1 g b.i.d. + levofloxacin 250 mg b.i.d. for 14 d. RESULTS: Out of 614 patients, still H. pylori-positive after first-line therapy, only 326 and 19 patients respectively rechecked their H. pylori status by UBT after the suggested second and third-line regimens. "Per protocol" eradication rates for first, second and thirdline therapy were 74.7% (95% CI: 72.7%-76.4%), 85.3% (95% CI: 81.1%-89.1%) and 89.5% (95% CI: 74.9%-103%) respectively. The overall percentage of patients with H. pylori eradicated after two treatments was 97.8% (95% CI: 97.1%-98.4%), vs 99.9% (95% CI: 99.8%-100%) after three treatments. The study found that eradication therapy was most effective in patients with ulcer disease (P < 0.05, P = 0.028), especially in those with duodenal ulcer. Smoking habits did not significantly affect the eradication rate. CONCLUSION: First-line therapy with amoxicillin and clarithromycin produces an H. pylori eradication rate comparable or superior to other studies and secondline treatment can still be triple therapy with amoxicillin and tinidazole.

Oxidation rate in the preparation of polyferric sulfate coagulant

The oxidation rate of ferrous sulfate was investigated in the preparation of polyferric sulfate(PFS) coagulant. It was proved that this reaction is zero order with respect to Fe2+, first order with respect to NO2(g) and first order with respect to the interface area between gas phase and liquid phase. If the partial pressure of NO2(g) in gas phase is increased or the interface area is increased, the time needed to complete the reaction will be decreased.

EFFECTS OF TEMPERATURE TREATMENT ON MICROSTRUCTURE AND PROPERTIES OF ZA27 ALLOY

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Surgery for gallbladder cancer:The need to generate greater evidence

The outcomes for gallbladder cancer remain largely dismal to this day.Overall,the low incidence of gallbladder cancer around the world coupled with an even lower number of patients amenable to surgery at the time of presentation,has precluded the generation of evidence-based guidelines for the management of this cancer.However,while the incidence of the cancer may be decreasing in some parts of the world,in other countries such as India,Japan and Chile,gallbladder cancer continues to affect a sizeable population of patients.As such,there is a growing need to define what constitutes an adequate surgery for each stage of this cancer,based on sound evidence.This editorial provides a broad overview of the existing problems in the management of gallbladder cancer and appeals for multi-institutional studies aimed at answering some of the pertinent questions on the surgical management of gallbladder cancer.

Current developments, problems and solutions in the non-surgical treatment of pancreatic cancer

Pancreatic cancer is a common malignant neoplasm of the pancreas with an increasing incidence, a low early diagnostic rate and a fairly poor prognosis. To date, the only curative therapy for pancreatic cancer is surgical resection, but only about 20% patients have this option at the time of diagnosis and the mean 5-year survival rate after resection is only 10%-25%. Therefore, developing new treatments to improve the survival rate has practical significance for patients with this disease. This review deals with a current unmet need in medical oncology: the improvement of the treatment outcome of patients with pancreatic cancer. We summarize and discuss the latest systemic chemotherapy treatments (including adjuvant, neoadjuvant and targeted agents), radiotherapy, interventional therapy and immunotherapy. Besides discussing the current developments, we outline some of the main problems, solutions and prospects in this field.

Efficacy of early treatment with infliximab in pediatric Crohn’s disease

AIM: To investigate the effectiveness of early infliximab use for induction and maintenance therapy in pediatric Crohn’s disease. METHODS: We performed a retrospective chart review of 36 patients with Crohn’s disease. Ten patients (group A) were treated with mesalamine after induction therapy with oral prednisolone, and 13 patients (group B) were treated with azathioprine after induction therapy with oral prednisolone. Thirteen patients (group C) received infliximab and azathioprine for induction and maintenance therapy for the first year, and were treated with azathioprine after 1 year. All patients were followed for at least 24 mo. Efficacy was determined by the relapse rate using the pediatric Crohn’s disease activity index score in each group at 12 and 24 mo. RESULTS: At the 1 year follow-up, the relapse ratee, Mi Jin Kim, Hae Jeong Lee, Yon Ho Choe (23.1%, 3 of 13 patients) in group C was lower than that (61.5%, 8 of 13 patients) in group B (P = 0.047). At the 2 years follow-up, the relapse rate (38.5%, 5 of 13 patients) in group C was lower than that (76.9%, 10 of 13 patients) in group B (P = 0.047). Adverse events in group C were fewer than in groups A and B. CONCLUSION: Early induction with infliximab at diagnosis, known as "top-down" therapy, was effective for reducing the relapse rate compared to conventional therapies for at least 2 years.

Effect of heat treatment temperature on dissimilar welded joint

The dissimilar metals 1Crl8Ni9 and 16MnR are welded by shielded metal arc welding process using electrode A312. The corrosion experiments are carried out on welded joint samples, which is as-welded and post-weld heat treatment at 650 ℃, 750 ℃ and 850 ℃, for 2 h in 70% sodium hydroxide solution. EDS and X-ray diffraction analysis are carried out on the samples after corrosion. Average corrosion rate calculation and microhardness measurement are conducted on both as- welded and post-weld heat treatment samples. The results indicate that average corrosion rate of as-welded joint metal is smaller than that of post-weld heat treatment joint metal. Compared with that of post-weld heat treatment at 750 ℃ and 850 ℃ for 2 h, the average corrosion rate of welded joint after post-weld heat treatment at 650 ℃ for 2 h increases greatly.

In situ measured growth rates of bainite plates in an Fe-C-Mn-Si superbainitic steel

The growth rates of bainite plates in an Fe-C-Mn-Si superbainitie steel were investigated by in situ observation. The lengthening rates of ferrite bainite during both cooling and isothermal holding processes were observed and the growth rates of bainite plates nucleating at grain boundaries, within grains and on preformed bainite were measured. It is indicated that the lengthening rates of bainite plates during the cooling and isothermal processes were different, and that the growth rates of bainite plates nucleating at different types of sites also demon- strated diversity. The bainite plates initiating at [vain boundaries during cooling grew the fastest, while the plates nucleating on preformed bainite did the slowest. However, the growth rate of the bainite plates nucleating at grain boundaries during isothermal transformation de- creased the most, whereas the bainite plates initiating within grains grew the fastest. In addition, the growth rate of ferrite bainite in the study supported the diffusion transformation mechanism of bainite from the viewooint of ~rowth rate.