Besides excellent biodegradability and biocompatibility,a useful tissue engineering scaffold should provide favorable surface properties,outstanding mechanical strength and controlled drug release property. In this pa...Besides excellent biodegradability and biocompatibility,a useful tissue engineering scaffold should provide favorable surface properties,outstanding mechanical strength and controlled drug release property. In this paper,a mild process to prepare porous tussah silk fibroin( TSF) scaffolds from aqueous solution was described. The n-butanol was used to control the self-assembly of tussah silk. The scaffolds with different TSF concentrations and the same volume showed differences in pore size and distribution. The maximum porosity of the poprepared porous scaffolds was 80% in this paper. And the pore size of the prepared porous scaffolds with different concentrations was between 10μm and 230 μm. X-ray diffraction( XRD) analysis revealed that amorphous TSF was crystallized to β-sheet secondary structure upon gelatin. The TSF scaffolds for controlled drug release was studied and the result showed that the time of drug release was significantly longer. The produced TSF scaffolds with sustained drug release have potential application in tissue engineering.展开更多
In this paper, study objects are raw and dilative tussah silk. By means of measuring and analyzing the fiber's diameter, linear density, diameter coefficient, thickness and fullness, this paper focuses on the infl...In this paper, study objects are raw and dilative tussah silk. By means of measuring and analyzing the fiber's diameter, linear density, diameter coefficient, thickness and fullness, this paper focuses on the influence of dilative technology on tussah silk's fiber and fabric. The results include the following three aspects: the diameter coefficient of dilative tussah silk fiber is increased by 10.35%, dilative tussah heather silk is thicker and fabric fullness is improved by 9%.展开更多
基金Collaborative Innovation Center of Textile and Garment Industry of Henan Province,China(No.hnfz14004)
文摘Besides excellent biodegradability and biocompatibility,a useful tissue engineering scaffold should provide favorable surface properties,outstanding mechanical strength and controlled drug release property. In this paper,a mild process to prepare porous tussah silk fibroin( TSF) scaffolds from aqueous solution was described. The n-butanol was used to control the self-assembly of tussah silk. The scaffolds with different TSF concentrations and the same volume showed differences in pore size and distribution. The maximum porosity of the poprepared porous scaffolds was 80% in this paper. And the pore size of the prepared porous scaffolds with different concentrations was between 10μm and 230 μm. X-ray diffraction( XRD) analysis revealed that amorphous TSF was crystallized to β-sheet secondary structure upon gelatin. The TSF scaffolds for controlled drug release was studied and the result showed that the time of drug release was significantly longer. The produced TSF scaffolds with sustained drug release have potential application in tissue engineering.
文摘In this paper, study objects are raw and dilative tussah silk. By means of measuring and analyzing the fiber's diameter, linear density, diameter coefficient, thickness and fullness, this paper focuses on the influence of dilative technology on tussah silk's fiber and fabric. The results include the following three aspects: the diameter coefficient of dilative tussah silk fiber is increased by 10.35%, dilative tussah heather silk is thicker and fabric fullness is improved by 9%.
