卵巢畸胎瘤是卵巢生殖细胞肿瘤中最常见的良性肿瘤,卵巢囊性畸胎瘤又称成熟性囊性畸胎瘤,是常见的畸胎瘤类型。卵巢畸胎瘤的内容物可由2~3个胚层的组织形成,含有皮肤及其附件、毛发、牙齿、神经、脂肪、骨骼等。虽然这些成分在理论上可...卵巢畸胎瘤是卵巢生殖细胞肿瘤中最常见的良性肿瘤,卵巢囊性畸胎瘤又称成熟性囊性畸胎瘤,是常见的畸胎瘤类型。卵巢畸胎瘤的内容物可由2~3个胚层的组织形成,含有皮肤及其附件、毛发、牙齿、神经、脂肪、骨骼等。虽然这些成分在理论上可以来自任何胚层,但实际上,完整地包含各种组织的畸胎瘤较为罕见。本文报道了一例合并美尼尔氏综合征、高血压、肥胖、II型糖尿病的女性患者,经过超声影像学提示卵巢畸胎瘤并手术治疗后发现畸胎瘤中含有皮肤、毛发、骨骼、牙齿、甲状腺组织的特殊病例。关于您提到的具体病例,即合并美尼尔氏综合征、高血压、肥胖、II型糖尿病的女性患者,超声影像学提示卵巢畸胎瘤,并在手术治疗后发现畸胎瘤中含有皮肤、毛发、骨骼、牙齿、甲状腺组织,这在临床诊疗中确实是一种罕见的病例。Ovarian teratoma is the most common benign tumor among ovarian germ cell tumors, and ovarian cystic teratoma, also known as mature cystic teratoma, is the most common type of teratoma. The contents of ovarian teratomas can be formed by tissues from two or three germ layers, including skin and its appendages, hair, teeth, nerves, fat, bones, etc. Although theoretically, these components can come from any germ layer, teratomas that fully contain various tissues are rare in practice. This article reports a special case of a female patient with Meniere’s syndrome, hypertension, obesity, and type II diabetes. Ultrasound imaging suggested an ovarian teratoma, and after surgical treatment, the teratoma was found to contain skin, hair, bones, teeth, and thyroid tissue. Regarding the specific case you mentioned, a female patient with Meniere’s syndrome, hypertension, obesity, and type II diabetes, in which ultrasound imaging suggested an ovarian teratoma, and post-surgery revealed the presence of skin, hair, bones, teeth, and thyroid tissue, this indeed represents a rare case in clinical practice.展开更多
目的探究复发性外阴阴道假丝酵母菌病(RVVC)患者阴道菌群的动态变迁。方法不同时间点采集RVVC患者(6例)以及正常对照女性(5例)阴道分泌物,分别对每个样本进行细菌总基因组DNA提取、16S r RNA V4区基因扩增及采用Illumina高通量测序技术...目的探究复发性外阴阴道假丝酵母菌病(RVVC)患者阴道菌群的动态变迁。方法不同时间点采集RVVC患者(6例)以及正常对照女性(5例)阴道分泌物,分别对每个样本进行细菌总基因组DNA提取、16S r RNA V4区基因扩增及采用Illumina高通量测序技术对扩增的PCR产物进行测序等步骤,然后通过BIPES、TSC、GAST等程序,分析比较两组阴道菌群物种丰度和结构以及菌群动态变化。结果正常对照女性阴道菌群以乳酸杆菌为主,其中惰性乳杆菌和卷曲乳杆菌比例相当,同时存在少量加德纳菌属、普氏菌属和其它菌属;或者以加德纳菌属、普氏菌属、奇异菌属、纤毛菌属等为主要菌属;而RVVC患者阴道菌群丰富度明显降低,以惰性乳杆菌为优势菌属,卷曲乳杆菌含量明显减少。正常对照女性阴道菌群随月经周期的变化出现波动,其中在月经期的波动最为明显,其优势菌属在月经周期中呈现相互交替或保持绝对优势的变化模式;而RVVC患者阴道菌群的波动性减弱,不随月经周期的变化而变化,且在疾病发作期和间歇期的菌群结构相似。结论 RVVC患者阴道菌群结构不随月经周期发生变化,在疾病发作期和间歇期相似。诱导卷曲乳杆菌产生或抑制惰性乳杆菌定植,从而恢复阴道菌群比例,可能可以治愈RVVC。展开更多
文摘卵巢畸胎瘤是卵巢生殖细胞肿瘤中最常见的良性肿瘤,卵巢囊性畸胎瘤又称成熟性囊性畸胎瘤,是常见的畸胎瘤类型。卵巢畸胎瘤的内容物可由2~3个胚层的组织形成,含有皮肤及其附件、毛发、牙齿、神经、脂肪、骨骼等。虽然这些成分在理论上可以来自任何胚层,但实际上,完整地包含各种组织的畸胎瘤较为罕见。本文报道了一例合并美尼尔氏综合征、高血压、肥胖、II型糖尿病的女性患者,经过超声影像学提示卵巢畸胎瘤并手术治疗后发现畸胎瘤中含有皮肤、毛发、骨骼、牙齿、甲状腺组织的特殊病例。关于您提到的具体病例,即合并美尼尔氏综合征、高血压、肥胖、II型糖尿病的女性患者,超声影像学提示卵巢畸胎瘤,并在手术治疗后发现畸胎瘤中含有皮肤、毛发、骨骼、牙齿、甲状腺组织,这在临床诊疗中确实是一种罕见的病例。Ovarian teratoma is the most common benign tumor among ovarian germ cell tumors, and ovarian cystic teratoma, also known as mature cystic teratoma, is the most common type of teratoma. The contents of ovarian teratomas can be formed by tissues from two or three germ layers, including skin and its appendages, hair, teeth, nerves, fat, bones, etc. Although theoretically, these components can come from any germ layer, teratomas that fully contain various tissues are rare in practice. This article reports a special case of a female patient with Meniere’s syndrome, hypertension, obesity, and type II diabetes. Ultrasound imaging suggested an ovarian teratoma, and after surgical treatment, the teratoma was found to contain skin, hair, bones, teeth, and thyroid tissue. Regarding the specific case you mentioned, a female patient with Meniere’s syndrome, hypertension, obesity, and type II diabetes, in which ultrasound imaging suggested an ovarian teratoma, and post-surgery revealed the presence of skin, hair, bones, teeth, and thyroid tissue, this indeed represents a rare case in clinical practice.
文摘目的探究复发性外阴阴道假丝酵母菌病(RVVC)患者阴道菌群的动态变迁。方法不同时间点采集RVVC患者(6例)以及正常对照女性(5例)阴道分泌物,分别对每个样本进行细菌总基因组DNA提取、16S r RNA V4区基因扩增及采用Illumina高通量测序技术对扩增的PCR产物进行测序等步骤,然后通过BIPES、TSC、GAST等程序,分析比较两组阴道菌群物种丰度和结构以及菌群动态变化。结果正常对照女性阴道菌群以乳酸杆菌为主,其中惰性乳杆菌和卷曲乳杆菌比例相当,同时存在少量加德纳菌属、普氏菌属和其它菌属;或者以加德纳菌属、普氏菌属、奇异菌属、纤毛菌属等为主要菌属;而RVVC患者阴道菌群丰富度明显降低,以惰性乳杆菌为优势菌属,卷曲乳杆菌含量明显减少。正常对照女性阴道菌群随月经周期的变化出现波动,其中在月经期的波动最为明显,其优势菌属在月经周期中呈现相互交替或保持绝对优势的变化模式;而RVVC患者阴道菌群的波动性减弱,不随月经周期的变化而变化,且在疾病发作期和间歇期的菌群结构相似。结论 RVVC患者阴道菌群结构不随月经周期发生变化,在疾病发作期和间歇期相似。诱导卷曲乳杆菌产生或抑制惰性乳杆菌定植,从而恢复阴道菌群比例,可能可以治愈RVVC。
