目的:评价针灸联合昂丹司琼片的针药结合的治疗策略在胃肠肿瘤化疗患者胃肠道反应中的干预效果。方法:受试对象来自于我院2022年4月至2023年4月收治的80例胃肠肿瘤化疗患者,排除因颅内转移、胃肠道梗阻导致的中枢性呕吐或器质性病变性...目的:评价针灸联合昂丹司琼片的针药结合的治疗策略在胃肠肿瘤化疗患者胃肠道反应中的干预效果。方法:受试对象来自于我院2022年4月至2023年4月收治的80例胃肠肿瘤化疗患者,排除因颅内转移、胃肠道梗阻导致的中枢性呕吐或器质性病变性呕吐患者后,结合盲法分组原则将患者依次纳入对照组(n = 40,予以昂丹司琼治疗)与研究组(n = 40,实施针灸联合昂丹司琼治疗),评价两组主要疗效、肝功能生化指标、安全性指标、营养状况。结果:较对照组,研究组患者症状积分水平更低(P 0.05)。结论:中医针灸配合昂丹司琼片形成的针药结合的治疗策略在满足了胃肠肿瘤化疗患者对胃肠道反应治疗需求的同时,也兼顾了安全性,价值显著,疗效确切,具有积极的应用前景。Objective: To evaluate the intervention efficacy of acupuncture combined with ondansetron tablets, a treatment strategy combining acupuncture and medicine, in the gastrointestinal response of patients with gastrointestinal tumor chemotherapy. Methods: Subjects were derived from 80 patients with gastrointestinal tumor chemotherapy admitted to our hospital from April 2022 to April 2023. After excluding patients with central vomiting due to intracranial metastasis, gastrointestinal obstruction, or vomiting due to organic lesions, patients were included in the control group (n = 40, ondansetron) and the study group (n = 40, acupuncture with ondansetron) in accordance with the principle of blinded grouping, to evaluate the main efficacy, biochemical index of liver function, safety index and nutritional status of the two groups. Results: Compared with the control group, the study group had a lower symptom score (P 0.05). Conclusion: The treatment strategy of acupuncture and medicine formed by Chinese acupuncture and moxibustion and ondansetron tablets not only meets the needs of gastrointestinal tumor chemotherapy patients for the treatment of gastrointestinal response, but also takes into account the safety, with significant value and definite efficacy, and has a positive application prospect.展开更多
静脉内平滑肌瘤病(Intravascular Leiomyomatosis, IVL)是临床中极为罕见的疾病,仅限于女性,好发于围绝经期或育龄期妇女,IVL源自子宫肌细胞或静脉血管平滑肌细胞,病理类型为良性肿瘤,但有不良的生物学行为,指向血管腔生长,会沿人体静...静脉内平滑肌瘤病(Intravascular Leiomyomatosis, IVL)是临床中极为罕见的疾病,仅限于女性,好发于围绝经期或育龄期妇女,IVL源自子宫肌细胞或静脉血管平滑肌细胞,病理类型为良性肿瘤,但有不良的生物学行为,指向血管腔生长,会沿人体静脉系统蔓延,累及腹盆腔静脉–下腔静脉–右心房–肺动脉。所以尽早诊断及准确评估是提高本病生存率的最好方法。影像学检查是早期发现病变及术后评估的最有效的无创方法。近年来临床对IVL的认知度逐渐提高,本文就笔者在临床中遇到的一例经病理证实的静脉内平滑肌瘤病患者,其病变生长延伸至左肺动脉,笔者对病例进行回顾性分析并进行相关文献复习,旨在为临床工作者提供相关诊断经验,提高临床医生对于IVL的认知水平与了解。Intravascular Leiomyomatosis (IVL) is an extremely rare clinical disease, limited to females and predominantly occurring in women during the perimenopausal or reproductive years. IVL originates from uterine myocytes or venous vascular smooth muscle cells, and pathologically is classified as a benign tumor. However, it exhibits unfavorable biological behavior, growing into the vascular lumen and spreading along the human venous system, involving the pelvic and abdominal veins, the inferior vena cava, the right atrium, and the pulmonary artery. Therefore, early diagnosis and accurate assessment are the best methods to improve the survival rate of this disease. Imaging examinations are the most effective non-invasive methods for early detection of lesions and postoperative assessment. In recent years, clinical awareness of IVL has gradually increased. This article reviews a case of IVL, pathologically confirmed in the clinic, with the lesion extending to the left pulmonary artery. The author conducts a retrospective analysis of the case and reviews relevant literature, aiming to provide diagnostic experience for clinical workers and to improve clinical doctors’ awareness and understanding of IVL.展开更多
腱黄色瘤主要由肌腱内胶原纤维增生、富含胆固醇酯的巨噬细胞(泡沫样细胞)及裂隙状胆固醇结晶局部沉积所致,跟腱为其最好发的部位,也常发生于髌腱、指间关节及肘关节等关节的伸肌腱处,四肢多发病例较为少见。目前多认为腱黄色瘤与高脂...腱黄色瘤主要由肌腱内胶原纤维增生、富含胆固醇酯的巨噬细胞(泡沫样细胞)及裂隙状胆固醇结晶局部沉积所致,跟腱为其最好发的部位,也常发生于髌腱、指间关节及肘关节等关节的伸肌腱处,四肢多发病例较为少见。目前多认为腱黄色瘤与高脂血症相关,主要发生于家族性高胆固醇血症(FH)、原发性高脂血症等脂质代谢异常患者。该文章笔者呈现并分析了1例经手术病理证实为腱黄色瘤的磁共振成像表现,并结合国内外大量的文献进行回顾复习总结,旨在提高本病的MRI诊断水平及经验,降低临诊断误诊率。Xanthoxanoma of tendon is mainly caused by intratendon collagen fibroplasia, cholesterol ester rich macrophages (foam cells) and fusiform cholesterol crystal deposition. The Achilles tendon is the most common site for xanthoxanoma, and it often occurs in the extensor tendon of patellar tendon, interphalangeal joint, elbow joint and other joints. Multiple cases in limbs are rare. At present, it is believed that tendon xanthoma is related to hyperlipidemia, which mainly occurs in patients with abnormal lipid metabolism such as familial hypercholesterolemia (FH) and primary hyperlipi-demia. In this paper, the author presented and analyzed the magnetic resonance imaging findings of a case of tendon xanthoma confirmed by surgery and pathology, and reviewed and summarized a large number of literatures at home and abroad, aiming to improve the MRI diagnosis level and experience of this disease, and reduce the clinical diagnosis and misdiagnosis rate.展开更多
文摘目的:评价针灸联合昂丹司琼片的针药结合的治疗策略在胃肠肿瘤化疗患者胃肠道反应中的干预效果。方法:受试对象来自于我院2022年4月至2023年4月收治的80例胃肠肿瘤化疗患者,排除因颅内转移、胃肠道梗阻导致的中枢性呕吐或器质性病变性呕吐患者后,结合盲法分组原则将患者依次纳入对照组(n = 40,予以昂丹司琼治疗)与研究组(n = 40,实施针灸联合昂丹司琼治疗),评价两组主要疗效、肝功能生化指标、安全性指标、营养状况。结果:较对照组,研究组患者症状积分水平更低(P 0.05)。结论:中医针灸配合昂丹司琼片形成的针药结合的治疗策略在满足了胃肠肿瘤化疗患者对胃肠道反应治疗需求的同时,也兼顾了安全性,价值显著,疗效确切,具有积极的应用前景。Objective: To evaluate the intervention efficacy of acupuncture combined with ondansetron tablets, a treatment strategy combining acupuncture and medicine, in the gastrointestinal response of patients with gastrointestinal tumor chemotherapy. Methods: Subjects were derived from 80 patients with gastrointestinal tumor chemotherapy admitted to our hospital from April 2022 to April 2023. After excluding patients with central vomiting due to intracranial metastasis, gastrointestinal obstruction, or vomiting due to organic lesions, patients were included in the control group (n = 40, ondansetron) and the study group (n = 40, acupuncture with ondansetron) in accordance with the principle of blinded grouping, to evaluate the main efficacy, biochemical index of liver function, safety index and nutritional status of the two groups. Results: Compared with the control group, the study group had a lower symptom score (P 0.05). Conclusion: The treatment strategy of acupuncture and medicine formed by Chinese acupuncture and moxibustion and ondansetron tablets not only meets the needs of gastrointestinal tumor chemotherapy patients for the treatment of gastrointestinal response, but also takes into account the safety, with significant value and definite efficacy, and has a positive application prospect.
文摘静脉内平滑肌瘤病(Intravascular Leiomyomatosis, IVL)是临床中极为罕见的疾病,仅限于女性,好发于围绝经期或育龄期妇女,IVL源自子宫肌细胞或静脉血管平滑肌细胞,病理类型为良性肿瘤,但有不良的生物学行为,指向血管腔生长,会沿人体静脉系统蔓延,累及腹盆腔静脉–下腔静脉–右心房–肺动脉。所以尽早诊断及准确评估是提高本病生存率的最好方法。影像学检查是早期发现病变及术后评估的最有效的无创方法。近年来临床对IVL的认知度逐渐提高,本文就笔者在临床中遇到的一例经病理证实的静脉内平滑肌瘤病患者,其病变生长延伸至左肺动脉,笔者对病例进行回顾性分析并进行相关文献复习,旨在为临床工作者提供相关诊断经验,提高临床医生对于IVL的认知水平与了解。Intravascular Leiomyomatosis (IVL) is an extremely rare clinical disease, limited to females and predominantly occurring in women during the perimenopausal or reproductive years. IVL originates from uterine myocytes or venous vascular smooth muscle cells, and pathologically is classified as a benign tumor. However, it exhibits unfavorable biological behavior, growing into the vascular lumen and spreading along the human venous system, involving the pelvic and abdominal veins, the inferior vena cava, the right atrium, and the pulmonary artery. Therefore, early diagnosis and accurate assessment are the best methods to improve the survival rate of this disease. Imaging examinations are the most effective non-invasive methods for early detection of lesions and postoperative assessment. In recent years, clinical awareness of IVL has gradually increased. This article reviews a case of IVL, pathologically confirmed in the clinic, with the lesion extending to the left pulmonary artery. The author conducts a retrospective analysis of the case and reviews relevant literature, aiming to provide diagnostic experience for clinical workers and to improve clinical doctors’ awareness and understanding of IVL.
文摘腱黄色瘤主要由肌腱内胶原纤维增生、富含胆固醇酯的巨噬细胞(泡沫样细胞)及裂隙状胆固醇结晶局部沉积所致,跟腱为其最好发的部位,也常发生于髌腱、指间关节及肘关节等关节的伸肌腱处,四肢多发病例较为少见。目前多认为腱黄色瘤与高脂血症相关,主要发生于家族性高胆固醇血症(FH)、原发性高脂血症等脂质代谢异常患者。该文章笔者呈现并分析了1例经手术病理证实为腱黄色瘤的磁共振成像表现,并结合国内外大量的文献进行回顾复习总结,旨在提高本病的MRI诊断水平及经验,降低临诊断误诊率。Xanthoxanoma of tendon is mainly caused by intratendon collagen fibroplasia, cholesterol ester rich macrophages (foam cells) and fusiform cholesterol crystal deposition. The Achilles tendon is the most common site for xanthoxanoma, and it often occurs in the extensor tendon of patellar tendon, interphalangeal joint, elbow joint and other joints. Multiple cases in limbs are rare. At present, it is believed that tendon xanthoma is related to hyperlipidemia, which mainly occurs in patients with abnormal lipid metabolism such as familial hypercholesterolemia (FH) and primary hyperlipi-demia. In this paper, the author presented and analyzed the magnetic resonance imaging findings of a case of tendon xanthoma confirmed by surgery and pathology, and reviewed and summarized a large number of literatures at home and abroad, aiming to improve the MRI diagnosis level and experience of this disease, and reduce the clinical diagnosis and misdiagnosis rate.
