目的:总结1例川崎病合并巨噬细胞活化综合征患儿的临床特点及诊疗经过,提高对该疾病的认识。方法:回顾性分析2023年1月山东大学附属威海市立医院儿科收治的1例川崎病合并巨噬细胞活化综合征患儿的临床特点及诊疗经过,并进行相关文献复...目的:总结1例川崎病合并巨噬细胞活化综合征患儿的临床特点及诊疗经过,提高对该疾病的认识。方法:回顾性分析2023年1月山东大学附属威海市立医院儿科收治的1例川崎病合并巨噬细胞活化综合征患儿的临床特点及诊疗经过,并进行相关文献复习。结果:患儿以发热、皮疹及结膜充血为突出表现,在诊断为川崎病后使用静注人免疫球蛋白、阿司匹林治疗,仍高热。加用糖皮质激素后体温降至正常,结合相关检查,诊断KD合并MAS。结论:对于川崎病患儿,若伴有三系减少或静注人免疫球蛋白治疗无效时,应考虑是否合并MAS,及时加用糖皮质激素,降低死亡率。Objective: To summarize the clinical characteristics and treatment outcome of 1 cases of Kawasaki disease complicated by macrophage activation syndrome so as to improve clinician’s awareness of the disease. Methods: Retrospective analysis of the clinical characteristics and diagnosis and treatment process of a child with Kawasaki disease complicated with macrophage activation syndrome admitted to the pediatrics department of Weihai Municipal Hospital affiliated with Shandong University in January 2023, and relevant literature review. Results: The child presented with prominent symptoms of fever, rash, and conjunctival congestion. After diagnosis of Kawasaki disease, intravenous immunoglobulin and aspirin were used for treatment, but the fever persisted. After adding glucocorticoids, the body temperature returned to normal, and combined with relevant examinations, KD was diagnosed with MAS. Conclusions: For children with Kawasaki disease, if there is a reduction in the three lineages or if intravenous immunoglobulin therapy is ineffective, consideration should be given to whether to combine MAS and timely use of glucocorticoids to reduce mortality.展开更多
目的:总结1例慢性活动性EB病毒感染相关性噬血细胞综合征患儿的临床特点及诊疗经过,提高对该疾病的认识。方法:回顾性分析2022年10月山东大学附属威海市立医院儿科收治的1例慢性活动性EB病毒感染相关性噬血细胞综合征患儿的临床特点及...目的:总结1例慢性活动性EB病毒感染相关性噬血细胞综合征患儿的临床特点及诊疗经过,提高对该疾病的认识。方法:回顾性分析2022年10月山东大学附属威海市立医院儿科收治的1例慢性活动性EB病毒感染相关性噬血细胞综合征患儿的临床特点及诊疗经过,并进行相关文献复习。结果:患儿以发热、反复肝损害、全血细胞减少、凝血功能紊乱为突出表现,病情发展迅速,短时间内死亡,结合相关检查,诊断为慢性活动性EB病毒感染相关性噬血细胞综合征。结论:对于慢性活动性EB病毒感染患儿,在明确诊断后应积极采取有效治疗措施,一旦引起相关噬血细胞综合征,死亡率极高。Objective: To summarize the clinical characteristics and diagnosis and treatment process of a child with chronic active EB virus infection associated hemophagocytic syndrome, and improve the understanding of this disease. Methods: Retrospective analysis of the clinical characteristics and diagnosis and treatment process of a child with chronic active EB virus infection associated hemophagocytic syndrome admitted to the pediatrics department of Weihai Municipal Hospital affiliated with Shandong University in October 2022, and relevant literature review. Results: The child presented with prominent symptoms such as fever, repeated liver damage, decreased whole blood cells, and coagulation dysfunction. The condition developed rapidly and died within a short period of time. Combined with relevant examinations, the diagnosis was chronic active EB virus infection associated hemophagocytic syndrome. Conclusions: For children with chronic active EB virus infection, effective treatment measures should be actively taken after a clear diagnosis. Once it causes related hemophagocytic syndrome, the mortality rate is extremely high.展开更多
目的:总结1例卵巢畸胎瘤蒂扭转患儿的临床特点及诊疗经过,提高对该疾病的认识。方法:回顾性分析2024年7月山东大学附属威海市立医院儿科收治的1例卵巢畸胎瘤蒂扭转患儿的临床特点及诊疗经过,并进行相关文献复习。结果:患儿以下腹痛、呕...目的:总结1例卵巢畸胎瘤蒂扭转患儿的临床特点及诊疗经过,提高对该疾病的认识。方法:回顾性分析2024年7月山东大学附属威海市立医院儿科收治的1例卵巢畸胎瘤蒂扭转患儿的临床特点及诊疗经过,并进行相关文献复习。结果:患儿以下腹痛、呕吐及低热为临床表现,在诊断为急性胃肠炎后予禁饮食、补液及止吐治疗,腹痛不缓解。完善腹部超声检查考虑畸胎瘤,急症行腹腔镜双侧卵巢肿瘤剥除术,最终诊断卵巢畸胎瘤蒂扭转。结论:对于下腹痛的女性儿童,需注意卵巢畸胎瘤可能,及时借助腹部超声检查明确诊断,避免误诊及漏诊对患儿造成不可逆的损害。Objective: To summarize the clinical characteristics and treatment outcome of 1 cases of torsion of ovarian teratoma pedicle in children so as to improve clinician’s awareness of the disease. Methods: Retrospective analysis of the clinical characteristics and diagnosis and treatment process of a child with torsion of ovarian teratoma pedicle admitted to the pediatrics department of Weihai Municipal Hospital affiliated with Shandong University in January 2024, and relevant literature review. Results: The clinical manifestations of the child are abdominal pain, vomiting, and low-grade fever. After being diagnosed with acute gastroenteritis, the child is treated with dietary restriction, fluid replacement, and antiemetic therapy, but the abdominal pain does not improve. Complete abdominal ultrasound examination to consider teratoma, emergency laparoscopic bilateral ovarian tumor resection surgery was performed, and the final diagnosis was ovarian teratoma torsion. Conclusions: For female children with lower abdominal pain, attention should be paid to the possibility of ovarian teratoma, and timely diagnosis should be confirmed through abdominal ultrasound examination to avoid misdiagnosis and missed diagnosis, which may cause irreversible damage to the child.展开更多
文摘目的:总结1例川崎病合并巨噬细胞活化综合征患儿的临床特点及诊疗经过,提高对该疾病的认识。方法:回顾性分析2023年1月山东大学附属威海市立医院儿科收治的1例川崎病合并巨噬细胞活化综合征患儿的临床特点及诊疗经过,并进行相关文献复习。结果:患儿以发热、皮疹及结膜充血为突出表现,在诊断为川崎病后使用静注人免疫球蛋白、阿司匹林治疗,仍高热。加用糖皮质激素后体温降至正常,结合相关检查,诊断KD合并MAS。结论:对于川崎病患儿,若伴有三系减少或静注人免疫球蛋白治疗无效时,应考虑是否合并MAS,及时加用糖皮质激素,降低死亡率。Objective: To summarize the clinical characteristics and treatment outcome of 1 cases of Kawasaki disease complicated by macrophage activation syndrome so as to improve clinician’s awareness of the disease. Methods: Retrospective analysis of the clinical characteristics and diagnosis and treatment process of a child with Kawasaki disease complicated with macrophage activation syndrome admitted to the pediatrics department of Weihai Municipal Hospital affiliated with Shandong University in January 2023, and relevant literature review. Results: The child presented with prominent symptoms of fever, rash, and conjunctival congestion. After diagnosis of Kawasaki disease, intravenous immunoglobulin and aspirin were used for treatment, but the fever persisted. After adding glucocorticoids, the body temperature returned to normal, and combined with relevant examinations, KD was diagnosed with MAS. Conclusions: For children with Kawasaki disease, if there is a reduction in the three lineages or if intravenous immunoglobulin therapy is ineffective, consideration should be given to whether to combine MAS and timely use of glucocorticoids to reduce mortality.
文摘目的:总结1例慢性活动性EB病毒感染相关性噬血细胞综合征患儿的临床特点及诊疗经过,提高对该疾病的认识。方法:回顾性分析2022年10月山东大学附属威海市立医院儿科收治的1例慢性活动性EB病毒感染相关性噬血细胞综合征患儿的临床特点及诊疗经过,并进行相关文献复习。结果:患儿以发热、反复肝损害、全血细胞减少、凝血功能紊乱为突出表现,病情发展迅速,短时间内死亡,结合相关检查,诊断为慢性活动性EB病毒感染相关性噬血细胞综合征。结论:对于慢性活动性EB病毒感染患儿,在明确诊断后应积极采取有效治疗措施,一旦引起相关噬血细胞综合征,死亡率极高。Objective: To summarize the clinical characteristics and diagnosis and treatment process of a child with chronic active EB virus infection associated hemophagocytic syndrome, and improve the understanding of this disease. Methods: Retrospective analysis of the clinical characteristics and diagnosis and treatment process of a child with chronic active EB virus infection associated hemophagocytic syndrome admitted to the pediatrics department of Weihai Municipal Hospital affiliated with Shandong University in October 2022, and relevant literature review. Results: The child presented with prominent symptoms such as fever, repeated liver damage, decreased whole blood cells, and coagulation dysfunction. The condition developed rapidly and died within a short period of time. Combined with relevant examinations, the diagnosis was chronic active EB virus infection associated hemophagocytic syndrome. Conclusions: For children with chronic active EB virus infection, effective treatment measures should be actively taken after a clear diagnosis. Once it causes related hemophagocytic syndrome, the mortality rate is extremely high.
文摘目的:总结1例卵巢畸胎瘤蒂扭转患儿的临床特点及诊疗经过,提高对该疾病的认识。方法:回顾性分析2024年7月山东大学附属威海市立医院儿科收治的1例卵巢畸胎瘤蒂扭转患儿的临床特点及诊疗经过,并进行相关文献复习。结果:患儿以下腹痛、呕吐及低热为临床表现,在诊断为急性胃肠炎后予禁饮食、补液及止吐治疗,腹痛不缓解。完善腹部超声检查考虑畸胎瘤,急症行腹腔镜双侧卵巢肿瘤剥除术,最终诊断卵巢畸胎瘤蒂扭转。结论:对于下腹痛的女性儿童,需注意卵巢畸胎瘤可能,及时借助腹部超声检查明确诊断,避免误诊及漏诊对患儿造成不可逆的损害。Objective: To summarize the clinical characteristics and treatment outcome of 1 cases of torsion of ovarian teratoma pedicle in children so as to improve clinician’s awareness of the disease. Methods: Retrospective analysis of the clinical characteristics and diagnosis and treatment process of a child with torsion of ovarian teratoma pedicle admitted to the pediatrics department of Weihai Municipal Hospital affiliated with Shandong University in January 2024, and relevant literature review. Results: The clinical manifestations of the child are abdominal pain, vomiting, and low-grade fever. After being diagnosed with acute gastroenteritis, the child is treated with dietary restriction, fluid replacement, and antiemetic therapy, but the abdominal pain does not improve. Complete abdominal ultrasound examination to consider teratoma, emergency laparoscopic bilateral ovarian tumor resection surgery was performed, and the final diagnosis was ovarian teratoma torsion. Conclusions: For female children with lower abdominal pain, attention should be paid to the possibility of ovarian teratoma, and timely diagnosis should be confirmed through abdominal ultrasound examination to avoid misdiagnosis and missed diagnosis, which may cause irreversible damage to the child.
