津液是机体一切正常水液的总称,是组成人体脏腑组织器官的基本物质,也是维持机体各器官功能正常运行及人体正常生命活动的必备基础。津液在人体中的异常衍化与急性胰腺炎的病理改变具有高度一致性。本文梳理人体津液代谢与胰腺功能的内...津液是机体一切正常水液的总称,是组成人体脏腑组织器官的基本物质,也是维持机体各器官功能正常运行及人体正常生命活动的必备基础。津液在人体中的异常衍化与急性胰腺炎的病理改变具有高度一致性。本文梳理人体津液代谢与胰腺功能的内在联系,分析了急性胰腺炎各阶段主要发生的津液病变衍化,强调津液代谢障碍是急性胰腺炎发作的核心病机。归纳出在急性发作期应做到疏肝利胆,清热利湿,通腑泻下,活血攻毒,治以祛邪为主,兼以顾护正气;缓解期则重在调理脾运,辨证用药,治以扶正为主,兼以祛除余邪;恢复期则在强健脾运的基础上做到分证论治,改变体质偏颇,同时注意调畅情志,起居有常,饮食调整,减少复发。Body fluid is the general name of all normal water in the body. It is the basic substance that makes up the viscera, tissues and organs of the human body, and is also the necessary basis for maintaining the normal functioning of all organs of the body and normal life activities of the human body. The abnormal evolution of body fluid in human body is highly consistent with the pathological changes of acute pancreatitis. This paper reviews the internal relationship between body fluid metabolism and pancreatic function, analyzes the evolution of body fluid lesions occurring in each stage of acute pancreatitis, and emphasizes that body fluid metabolism disorders are the core pathogenesis of acute pancreatitis. It is concluded that in the acute attack period, we should achieve the functions of soothing the liver and promoting bile flow, clearing heat and removing dampness, promoting bowel movements, activating blood circulation and attacking to xins. The treatment should focus on dispelling evil, while also taking care of the healthy atmosphere;In the remission period, the focus is on regulating spleen transport, differentiation of symptoms and drugs, mainly on fuzheng, and eliminating residual evil;In the recovery period, on the basis of strengthening the spleen movement, it can be treated according to different syndromes, change the physical bias, and pay attention to regulating emotions, living regularly, diet adjustment, and reducing recurrence.展开更多
目的研究扶阳祛邪方在脑缺血再灌注损伤患者中的应用效果及增效减毒作用。方法采取随机便利抽样法选取2019年10月—2020年9月医院脑缺血再灌注损伤患者68例为研究对象,按照单双号法将其随机分为观察组和对照组(各34例)。对照组予以常规...目的研究扶阳祛邪方在脑缺血再灌注损伤患者中的应用效果及增效减毒作用。方法采取随机便利抽样法选取2019年10月—2020年9月医院脑缺血再灌注损伤患者68例为研究对象,按照单双号法将其随机分为观察组和对照组(各34例)。对照组予以常规西医治疗方案,观察组在对照组治疗基础上结合扶阳祛邪方,7 d为1个疗程、连续两个疗程。观察和比较治疗前后两组患者中医证候评分、神经功能缺损积分(National Institutes of health neurological deficit score,NIHSS)和B细胞淋巴瘤2(B-cell lymphoma-2,Bcl-2)、Bcl-2相关x蛋白(Bcl-2 associatea x protein,Bax)、半胱氨酸天冬氨酸蛋白酶-3(Cysteinyl aspartate specfic protease,Caspase-3)蛋白表达水平。结果观察组总有效率94.12%(32/34)高于对照组的82.35%(28/34),差异有统计学意义(P<0.05)。治疗后较治疗前,两组患者NIHSS评分和血清Bax、Caspase-3蛋白表达均下降,Bcl-2蛋白表达均升高,且治疗后观察组NIHSS评分和血清Bax、Caspase-3蛋白表达均低于对照组,Bcl-2蛋白表达高于对照组,差异有统计学意义(P<0.05)。结论扶阳祛邪方通过调控脑缺血再灌注损伤患者血清Caspase-3、Bcl-2与Bax蛋白表达水平而具有抗神经细胞凋亡等作用,可使患者收获良好的增效减毒效应,更大程度地保护脑神经功能。展开更多
文摘津液是机体一切正常水液的总称,是组成人体脏腑组织器官的基本物质,也是维持机体各器官功能正常运行及人体正常生命活动的必备基础。津液在人体中的异常衍化与急性胰腺炎的病理改变具有高度一致性。本文梳理人体津液代谢与胰腺功能的内在联系,分析了急性胰腺炎各阶段主要发生的津液病变衍化,强调津液代谢障碍是急性胰腺炎发作的核心病机。归纳出在急性发作期应做到疏肝利胆,清热利湿,通腑泻下,活血攻毒,治以祛邪为主,兼以顾护正气;缓解期则重在调理脾运,辨证用药,治以扶正为主,兼以祛除余邪;恢复期则在强健脾运的基础上做到分证论治,改变体质偏颇,同时注意调畅情志,起居有常,饮食调整,减少复发。Body fluid is the general name of all normal water in the body. It is the basic substance that makes up the viscera, tissues and organs of the human body, and is also the necessary basis for maintaining the normal functioning of all organs of the body and normal life activities of the human body. The abnormal evolution of body fluid in human body is highly consistent with the pathological changes of acute pancreatitis. This paper reviews the internal relationship between body fluid metabolism and pancreatic function, analyzes the evolution of body fluid lesions occurring in each stage of acute pancreatitis, and emphasizes that body fluid metabolism disorders are the core pathogenesis of acute pancreatitis. It is concluded that in the acute attack period, we should achieve the functions of soothing the liver and promoting bile flow, clearing heat and removing dampness, promoting bowel movements, activating blood circulation and attacking to xins. The treatment should focus on dispelling evil, while also taking care of the healthy atmosphere;In the remission period, the focus is on regulating spleen transport, differentiation of symptoms and drugs, mainly on fuzheng, and eliminating residual evil;In the recovery period, on the basis of strengthening the spleen movement, it can be treated according to different syndromes, change the physical bias, and pay attention to regulating emotions, living regularly, diet adjustment, and reducing recurrence.
文摘目的研究扶阳祛邪方在脑缺血再灌注损伤患者中的应用效果及增效减毒作用。方法采取随机便利抽样法选取2019年10月—2020年9月医院脑缺血再灌注损伤患者68例为研究对象,按照单双号法将其随机分为观察组和对照组(各34例)。对照组予以常规西医治疗方案,观察组在对照组治疗基础上结合扶阳祛邪方,7 d为1个疗程、连续两个疗程。观察和比较治疗前后两组患者中医证候评分、神经功能缺损积分(National Institutes of health neurological deficit score,NIHSS)和B细胞淋巴瘤2(B-cell lymphoma-2,Bcl-2)、Bcl-2相关x蛋白(Bcl-2 associatea x protein,Bax)、半胱氨酸天冬氨酸蛋白酶-3(Cysteinyl aspartate specfic protease,Caspase-3)蛋白表达水平。结果观察组总有效率94.12%(32/34)高于对照组的82.35%(28/34),差异有统计学意义(P<0.05)。治疗后较治疗前,两组患者NIHSS评分和血清Bax、Caspase-3蛋白表达均下降,Bcl-2蛋白表达均升高,且治疗后观察组NIHSS评分和血清Bax、Caspase-3蛋白表达均低于对照组,Bcl-2蛋白表达高于对照组,差异有统计学意义(P<0.05)。结论扶阳祛邪方通过调控脑缺血再灌注损伤患者血清Caspase-3、Bcl-2与Bax蛋白表达水平而具有抗神经细胞凋亡等作用,可使患者收获良好的增效减毒效应,更大程度地保护脑神经功能。
