The study investigates cybersecurity challenges in Nigerian deposit money banks (DMBs) with a focus on proactive measures taken by banks and customers to overcome these challenges. The research design employs a descri...The study investigates cybersecurity challenges in Nigerian deposit money banks (DMBs) with a focus on proactive measures taken by banks and customers to overcome these challenges. The research design employs a descriptive approach and census sampling, with data collected from staff of selected DMBs using questionnaires. Data analysis was conducted using SPSS, and findings indicate that the major challenges confronting cybersecurity in banks were pharming, identity theft, SIM Swap fraud, Skimming/Website cloning and Smishing/Vishing. The major factors responsible were found to include loopholes in the banks’ internal control system, insider abuse by bank staff, ignorance and lack of security consciousness among the banking customers etc. it was found that banks implement measures such as encryption, password changes, and blocking unsolicited messages to mitigate cybersecurity risks. The study concludes with recommendations for continuous security updates, internal control reviews, and customer education campaigns. While the study addresses an important topic, there are areas where clarity, depth, and methodological rigor could be strengthened for a more robust contribution to the field.展开更多
The study is focused on agricultural credit sources and determinants of credit acquisition by farmers in ldemili local government area of Anambra State, Nigeria with specific objectives to: describe socio-economic ch...The study is focused on agricultural credit sources and determinants of credit acquisition by farmers in ldemili local government area of Anambra State, Nigeria with specific objectives to: describe socio-economic characteristics of rural farmers; identify sources of agricultural credit available to rural farmers; determine socio-economic factors that influence agricultural credit acquisition of farmers; ascertain reasons for any credit misappropriation and identify problems that constrain farmers from agricultural credit acquisition. Ninety farmers were randomly selected by multi stage random sampling technique. Semi-structured questionnaire was used to elicit data for the study. Descriptive statistics and multiple regression model were used in achieving the objectives. Results indicated that 74.44% of respondents were males with a mean age of 45 years. Majority (76.67%) were married with large house hold sizes. Majority (93.33%) received different level of education, with sources of credit from friends/relatives (30.00%), cooperative societies (43.33%), money lenders (14.44%), and cumulatively from formal sources ((12.22%). The result of the multiple regression analysis revealed age, household size, membership of cooperative societies, marital status, education level, farm size and amount of loan repaid at varied signs and levels as significant predictors of amount of agricultural credit acquired by farmers. The most common reason given among the respondents (55.89%) of those who misappropriated acquired agricultural credit, was meeting nonfood needs of the household. The farmers encountered problems of high interest rate (78.89%), lack of collateral (75.56%), long distance from source of credit (50.00%), poor harvest (37.78%), moratorium (33.33%) and delay in loan approval/disbursement (44.44%) as constraints to acquire credit. The study recommends that the state government should pass policies aimed at providing free educative seminars to all illiterate farmers to teach them possible ways and methods of acquiring credit. To ensure mass attendance to such seminars, little incentives should be given to farmer participants.展开更多
<strong>Introduction: </strong>Hepatitis B virus (HBV) infection is a major cause of prenatal death worldwide. Chronic hepatitis B (CHB) infection is associated with an increased risk of cirrhosis, hepatic...<strong>Introduction: </strong>Hepatitis B virus (HBV) infection is a major cause of prenatal death worldwide. Chronic hepatitis B (CHB) infection is associated with an increased risk of cirrhosis, hepatic decomposition, and hepatocellular carcinoma (HCC). <strong>Objective:</strong> This project work surveyed the prevalence of hepatitis B among febrile patients as well as to detect hepatitis B virus in the blood and the stage of the infection of hepatitis B on the affected patients and carrier stage or state of immunity of the affected patients. <strong>Methodology:</strong> A well-designed questionnaire/checklist was used to gather information regarding age, HIV-Status, and sex from 50 febrile patients. 2 ml of blood sample was obtained by venin-puncture using a sterile hypodermic syringe and emptied into a clean dry tube (without anticoagulant) observing the necessary aseptic techniques. The blood was centrifuged and the sera obtained and stored at 2 - 8 c for HBsAg screening. Hepatitis B virus was tested using an<em> in-vitro </em>diagnostic kit called HBsAg one-step rapid test strip. The HBsAg one-step rapid test is a lateral flow chromatographic immunoassay based on the principle of the double antibody-sandwich technique. The membrane is pre-coated with anti-HBsAg antibodies on the test line region of the test. During testing, the serum specimen reacts with the particle coated with anti-HBsAg antibody. The serum moves up with capillary action to react with the coated antibody on the membrane. Then, the colored line (positive) will be generated which shows the presence of the virus. But negative shows absence of the virus. The blood in the test tube was spun using a centrifuge to separate the red cells from the serum. The test pouch, serum, and control were allowed to equilibrate to room temperature before testing. The test strip was removed from the sealed pouch and used immediately. The test strip was immersed vertically into the serum with the arrows pointing towards the serum for about 10 - 15 seconds, without exceeding the maximum line on the test strip. The strip was placed on a non-absorbent flat surface. The time was set and the result read after 15 minutes and recorded. The procedure was repeated for each sample and the results were recorded accordingly. The test is positive when two red lines appear on the test region (T) and control region (C) only. The result is said to be invalid when one line appears on the test region (T) and non on the control region (C) and also when no line appears on both the test region (T) and control region (C). <strong>Results:</strong> After interpretation of the result of the test on fifty patients,<strong> Table 1</strong> shows the age range of the population. The total distribution of subjects concerning age was as follows: 4 out of 50 populations (8%) were observed for the age range of 0 - 10;7 out of 50 (14%) were observed of the age range of 11 - 20;28 out of 50 (56%) were observed for a range of 21 - 30;9 out of 50 (18%) were observed for the age range of 31 - 40;2 out of 50 (4%) were observed at the age range of 21 - 30 with percentage seroprevalence of 4%. There is no significant correlation in the age group concerning percentage seroprevalence (P = 0.05). Also, the sex of the study population as seen in <strong>Table 2</strong> shows that 21 were males and 29 were females. Out of the 21 males population, 3 (14.24%) were positive. In the female population, 5 out of 29 (17.24%) were positive. The prevalence of the population concerning their sex was tested using Pearson’s chi-square and it was concluded that there is no significant relationship between sex and seroprevalence of hepatitis B. <strong>Table 3 </strong>shows the HIV of the study population and it shows that 6 out of 14 HIV positive patients (42.56%) were positive and 3 out of 36 HIV-negative patients (4.55%)) were positive. The prevalence of the population concerning HIV status was tested using Pearson’s chi-square and it was concluded that there is a significant association between HIV status and seroprevalence of hepatitis B. <strong>Conclusion: </strong>In conclusion, this study shows that there is a low prevalence of hepatitis B among febrile patients at the study area, hence limiting fever as a major determinant of hepatitis B infection. Considering the high risk of HBV in HIV co-infected patients, there is a need for the screening of HIV-infected patients for hepatitis B and appropriate therapy followed up on possible HBV-HIV co-infected patients. Appropriate preventive measures especially vaccination against hepatitis B virus should be encouraged among the susceptible population.展开更多
Background: Healthcare workers are challenged by an imposing group of occupational hazards. These hazards include exposure to biological and non-biological hazards like ionizing radiation, stress, injury, infectious a...Background: Healthcare workers are challenged by an imposing group of occupational hazards. These hazards include exposure to biological and non-biological hazards like ionizing radiation, stress, injury, infectious agents, and chemicals. The aim of this study was to assess common occupational hazards among health workers at the Department of Health Services (DHS), Federal University of Technology, Owerri. Methods: A hospital-based cross-sectional study design was employed for the study, and a self-administered questionnaire was used for data collection. The SPSS Version 22.0 software was used for the analysis of the descriptive statistics obtained from the study. This study included both clinical and non-clinical health workers. A purposive sampling technique was used in recruiting a total of 94 respondents who participated in the study from September 2020 to April 2021. Results: A total of 94 respondents who participated in the study and among the participants, 33.3% (31) of the respondents were aged 31 - 40 years, and the majority of the health workers, 43.6% (41) had stayed between 1 - 5 years. Also, 92.6% (87) of the health workers have heard of occupational hazards. The study showed that 84.0% (79) of health workers had good knowledge of common occupational hazards. Biological hazards among health workers are 47.9% (45) cuts and wounds, 29.8% (28) direct contact with contaminated specimens/hazardous materials, and 26.6% (26) sharp related injuries, while for non-biological hazards, 44.7% (42) have slipped, tripped or fallen, and 35.1% (33) have been stressed. Common safety measures include 86.2% (81) washing their hands regularly;78.7% (74) using hand gloves;and 85.1% (80) agreeing they use face masks. Conclusion: Despite good knowledge of occupational hazards, participants at DHS were faced with certain hazards. It is recommended that the university, government, and policymakers revise and implement actions to provide health workers at DHS with equipment to encourage safety in work activity.展开更多
Nurses must deliver infusions as prescribed since too slow or fast a dose could be deleterious to patients. Nurses experience challenges with infusion dose calculations, making them vulnerable to errors. The research ...Nurses must deliver infusions as prescribed since too slow or fast a dose could be deleterious to patients. Nurses experience challenges with infusion dose calculations, making them vulnerable to errors. The research team examined drop factor and infusion dose calculation discrepancies among nurses in southern Nigeria. Five university teaching hospitals were involved in this cross-sectional study conducted in 2019. To establish the drop factor of commonly available macro drip sets, the team randomly sourced 25 macro drip sets from the hospitals’ pharmacies. A sample of 291 nurses was selected using a proportionate random sampling technique. The team collected data using the Adult Infusion Dose Calculation Quiz and analyzed it at a 5% significance level. Twenty (80%) of the sampled macro drip sets displayed a drop factor value of 20 drops per milliliter (gtt/ml) on their packaging. When measured experimentally, 25 (100%) of the macro drip sets delivered exactly 20 gtt/ml. Only 36 (12.4%) respondents calculated macro drip infusion doses using the correct drop factor of 20 gtt/ml. Non-attendance of infusion administration training updates significantly increased the risk of error by 38% (p ≤ 0.001). In conclusion, the drop factor of macro drip sets used in southern Nigeria is 20 gtt/ml;nurses were prone to infusing patients at a lower dose than prescribed. Special training in infusion therapy might remedy this concern.展开更多
Problem Statement: Malaria’s global impact necessitates effective treatments, like dihydroartemisinin-piperaquine (DHA/PQP), though safety concerns, notably drug-induced cardiotoxicity (DICT), persist. A knowledge ga...Problem Statement: Malaria’s global impact necessitates effective treatments, like dihydroartemisinin-piperaquine (DHA/PQP), though safety concerns, notably drug-induced cardiotoxicity (DICT), persist. A knowledge gap exists regarding DHA/PQP’s cardiac effects, warranting a comprehensive investigation. Approach: This study aimed to assess KROSH (DHA/PQP) impact on albino rat heart histology, examining structural changes and potential cardiotoxicity. 40 albino rats were grouped by KROSH dosage and duration, monitored for weight changes, and heart tissues were examined using hematoxylin and eosin (H & E) staining. Statistical analysis compared to control and treated groups. Results: KROSH administration led to varying rat weight effects, yet not statistically significant. Histological analysis revealed dose and duration-dependent cardiac tissue alterations, including distortion, adipose deposits, artery hypertrophy, fibrosis, and necrosis. These contrasts with prior research documenting DHA/PQP’s non-toxic effects. Conclusion/Recommendation: This study highlights potential KROSH (DHA/PQP) cardiotoxicity concerns through histological changes, underscoring the need for further research into underlying mechanisms and human health implications. Given DHA/PQP’s wide use, these findings should inform safety evaluations and administration practices.展开更多
Background: This study aimed to assess the toxicity of Irvingia gabonensis leaf extracts in albino rats and investigate their effects on body weight, liver function parameters, and renal function parameters. The resea...Background: This study aimed to assess the toxicity of Irvingia gabonensis leaf extracts in albino rats and investigate their effects on body weight, liver function parameters, and renal function parameters. The research specifically compared the outcomes of aqueous and ethanol extraction methods. Methods: Acute toxicity was evaluated by administering a single oral dose of Irvingia gabonensis leaf extracts to rats and monitoring them for 24 hours and during a 14-day observation period. Sub-acute toxicity was assessed through a 28-day administration of the leaf extract. Body weight changes, liver function parameters, and renal function parameters were measured and compared among treatment groups. Results: No signs of toxicity or mortality were observed in rats treated with Irvingia gabonensis leaf extracts obtained through either aqueous or ethanol extraction methods. The calculated lethal dose required to cause mortality in 50% of the tested animals (LD<sub>50</sub>) exceeded 5000 mg/kg body weight. Oral administration of the leaf extract at doses of 400 and 800 mg/kg body weight did not induce any observable signs of toxicity or adverse effects during the 28-day study period. Male and female albino rats treated with the leaf extract showed significant weight gains compared to the control group. Higher doses (800 mg/kg) of both aqueous and ethanol extracts led to increased levels of total protein, albumin, and globulin in male albino rats, with the ethanol extract exhibiting a more pronounced effect. The administration of the ethanol extract, particularly at the lower dose (400 mg/kg), resulted in decreased levels of liver enzymes (AST, ALT, and ALP), suggesting potential liver protective properties. Additionally, bilirubin levels, a marker of liver dysfunction, were significantly reduced in all treatment groups, with the lowest levels observed in the groups receiving higher doses of both aqueous and ethanol extracts. The administration of Irvingia gabonensis leaf extracts did not significantly affect renal function parameters in both male and female albino rats. Conclusion: Irvingia gabonensis leaf extracts obtained through aqueous and ethanol extraction methods showed no acute or sub-acute toxicity in albino rats. The extracts demonstrated potential beneficial effects on liver function parameters, particularly at higher doses. However, further research is needed to validate these findings and determine the optimal dosage for potential therapeutic applications in humans.展开更多
Background: The burden of COVID-19 and human immunodeficiency virus (HIV) are some of the major and persistent global health challenges of the twenty-first century. HIV and COVID-19 are expected to overlap in high HIV...Background: The burden of COVID-19 and human immunodeficiency virus (HIV) are some of the major and persistent global health challenges of the twenty-first century. HIV and COVID-19 are expected to overlap in high HIV-burden countries, posing several public health challenges as a result. Prisons are overcrowded, have limited space for social distancing and have inadequate ventilation systems, making it difficult to contain the spread of COVID-19 in addition to the high-risk behaviours of inmates which contribute to the spread of HIV within these facilities. This study aimed to determine the prevalence of COVID-19 among inmates in a prison facility with a relatively high HIV burden in Port Harcourt, Nigeria;investigating potential risk factors and co-infection with HIV. Methodology: The study employed a descriptive cross-sectional study design sampling 200 inmates from the Port Harcourt Maximum Security Custodial Centre from July to December 2022. A well-structured questionnaire was administered via interviews in addition to screening for HIV-1/2 antibodies as well as COVID-19 antigens using rapid diagnostic test kits. Descriptive statistics and chi-square were carried out on the GraphPad Prism 9 software with statistical significance defined as a p-value of less than 0.05 at a 95% confidence interval. Result: The prevalence of HIV from the current study was 6.5%, COVID-19 prevalence was reported to be 12.5% while HIV/COVID-19 co-infection was 1.5% The duration of incarceration, face mask use, frequent visitations and vaccination against COVID-19 were found to be significantly associated with the prevalence of COVID-19 in the studied population (p Conclusion: The current study reports a relatively high prevalence of HIV and COVID-19 among the inmates in the study area. It becomes expedient for the administrators of the correctional facility to properly screen new inmates for COVID-19, quarantine and manage cases, as well as provide them with personal protective equipment such as face masks. In-person visitation should be balanced with measures to prevent the spread of the infection, and mass vaccination campaigns should be promoted. Improving access to HIV screening and therapy for all prisoners should be prioritised to identify and manage the incidence of HIV early, reducing the risk of transmission, mitigating comorbidities and improving health outcomes.展开更多
Pawpaw and lime juices were blended to produce mixed pawpaw/lime juice samples in the ratios of 90:10, 80:20, 70:30, 60:40 and 50:50) v/v giving samples A, B, C, D and E respectively. The moisture, mineral and vitamin...Pawpaw and lime juices were blended to produce mixed pawpaw/lime juice samples in the ratios of 90:10, 80:20, 70:30, 60:40 and 50:50) v/v giving samples A, B, C, D and E respectively. The moisture, mineral and vitamin contents, as well as the physical, microbiological and sensory qualities of the individual juices and blended samples were evaluated. While lime juice had higher moisture, calcium and vitamin C with values of 97.90%, 2.21 mg/100 g and 67.47 mg/100 g as compared to pawpaw juice with 92.96%, 1.53 mg/100 g and 35.49 mg/100 g respectively;the pawpaw juice had higher ash, phosphorus and vitamin A contents, with values of 3.12%, 54.97 mg/100 g and 5.90 IU/100 g as against 2.84%, 29.53% and 0.16% for lime juice respectively. While there was a general increase in moisture, calcium and vitamin C contents with blending, ash, phosphorus and vitamin A contents increased with increase in lime. The total solids content and specific gravity of pawpaw juice were remarkably higher at 7.04% and 1.15 g/m3 compared to 2.09% and 1.09 g/m3 respectively for lime juice. However, lime juice had a higher titratable acidity, while recording a lower pH of 2.89 as compared to 5.36 for pawpaw juice. The Total Viable Count (TVC) of lime juice was much lower (2.33 × 105 CFU/ml) than that of pawpaw juice (5.33 × 106 CFU/ml). There was significant difference (p < 0.05) in all the sensory parameters evaluated. Generally, there was an increase in the scores of each parameter from sample A to B and then a decline through to sample E. Sample B (80:20) mixed pawpaw/lime juice was most preferred, while sample E (50:50) was least preferred.展开更多
Marshlands are important ecosystem for living organisms. The Southern Iraqi Marshland is the central habitat for freshwater fish, provides habitat for important populations of wildlife and serves as a source of income...Marshlands are important ecosystem for living organisms. The Southern Iraqi Marshland is the central habitat for freshwater fish, provides habitat for important populations of wildlife and serves as a source of income for native economies through reed harvesting. Studies have shown that variability in climate and human-induced factors affects the spatial dynamics of marsh ecosystems. This study assessed wetland changes in the Southern Iraqi Marshlands using Remotely Sensed Data from 1986 to 2019 using Landsat satellite imagery for four epochs: 1986, 2000, 2010 and 2019. To achieve this, thirty (30) pixels were obtained in selected land cover theme and their signatures were merged into one class. Furthermore, the selected pixels were recoded and merged into ten (10) land cover classes. The multi-layer classes created were shallow water, deep water, dense marsh, medium marsh, sparse marsh, dense vegetation, medium vegetation, sparse vegetation, dry soil and wet soil. The areal extents of the land cover types were calculated for 1986, 2000, 2010 and 2019. Normalized Difference Vegetation Index (NDVI) differencing was also carried in order to highlight trends in vegetation from 1986 to 2019. The study correlated historical trends of human activities as a central factor in the degradation of marshland (by 16.25%) from 1986 to 2000. However, by the year 2000 to 2010, there was an 11.36% increase in the total marshland area, which remained almost unchanged between 2010 and 2019. In 1986, NDVI was relatively stable at 0.73 in the Al-Hammar and Al-Hwaizeh Marsh. However, by 2000, the areas of dense vegetation cover reduced drastically by over 90%. In 2010, the NDVI index indicated trends of increasing water body and an outward cluster of healthier vegetation continuing to 2019.展开更多
This study explores the potentials of employing an Organic Rankine Cycle (ORC) system with variable inlet guide vanes (VIV) turbine geometry designed on a GT-Suite platform for effective exhaust heat recovery (EHR) ap...This study explores the potentials of employing an Organic Rankine Cycle (ORC) system with variable inlet guide vanes (VIV) turbine geometry designed on a GT-Suite platform for effective exhaust heat recovery (EHR) application onboard passenger vehicles. The ORC model simulation was based on vehicle speed mode using R245fa as working fluid to assess the thermal performance of the ORC system when utilizing modified turbine geometry. Interestingly, the model achieved a very improved performance in contrast to the model without a modified turbine configuration. The results revealed the average 2.32 kW ORC net output, 4.93% thermal efficiency, 6.1% mechanical efficiency, and 5.0% improved brake specific fuel consumption (BSFC) for the developed model. As determined by the performance indicators, these promising results from the model study show the prospect of EHR technology application in the transportation sector for reduction in exhaust emissions and fuel savings.展开更多
Background: Oedema, a constant feature of childhood nephrotic syndrome can be severe, enough to cause respiratory embarrassment. It can also be refractory to diuretic monotherapy. In such cases, combination of salt po...Background: Oedema, a constant feature of childhood nephrotic syndrome can be severe, enough to cause respiratory embarrassment. It can also be refractory to diuretic monotherapy. In such cases, combination of salt poor albumin (SPA) infusion and diuretics has remained the best treatment option. However, the cost of SPA has made it practically unavailable in resource-poor settings. It becomes a therapeutic dilemma when nephrotic syndrome patients of financially-constrained caregivers present with refractory anasarca in a resource-poor settings. Case review: We present a seven-year-old boy with relapsed steroid sensitive nephrotic syndrome who presented to Abia State University Teaching Hospital Aba, in respiratory distress with anasarca and a weight of 58 kilograms. SPA could not be accessed due to financial constraints. A decision to use fresh whole blood in the place of SPA, in combination with frusemide, achieved a lifesaving diuresis and regression of the anasarca. Conclusion: Whole blood is a good alternative for the treatment of refractory oedema in children with nephrotic syndrome in resource poor settings.展开更多
Multilingualism and multiculturalism have become so characteristic of our times that it is hard to come by a literary work that is strictly monolingual. Languages in contact influence each other in various ways. One l...Multilingualism and multiculturalism have become so characteristic of our times that it is hard to come by a literary work that is strictly monolingual. Languages in contact influence each other in various ways. One language could be more influential than the other as a result of linguistic and non-linguistic factors. A language that is documented and enjoys a more privileged political, economic, cultural, or religious position is likely to be more influential than another language that lacks these qualities. Languages in contact often borrow words from each other though a language that is considered to be more prestigious than another is more likely to be the donor language less prestigious one. Loanwords are therefore common among languages in contact. Intercultural literary communication is mostly effected through translation. Due to Africa's colonial experience, literary translation practice in Africa often involves European languages, Arabic, and indigenous African languages. In Nigeria, the languages that have played significant roles in literary translation include English, French, German, Arabic, and indigenous Nigerian languages. Franz Kafka's Brief an den Vater which was written in German has been translated into English as Letter to His Father by Ernest Kaiser and Eithne Wilkins and into Igbo as Soro Okwu m maobu Leta (Ndi) Nna by Felicia Ibemesi. This paper sets out to study loanwords in the English and Igbo translations from a target reader's perspective展开更多
The antioxidant of seeds was carried out using extracts from methanol and Silver Nanoparticles from the spice. The SEM shows the shapes, dispersion and agglomeration of the sample, while the EDX confirms the SEM and t...The antioxidant of seeds was carried out using extracts from methanol and Silver Nanoparticles from the spice. The SEM shows the shapes, dispersion and agglomeration of the sample, while the EDX confirms the SEM and the presence of some compounds. The FT-IR reveals the AgNP<sub>s</sub> capping and reducing the particular biomolecule from the functional group for identification. Compounds found in the FT-IR seeds of Capsicum annum are Ag L (Silver iodide), C K (Cyanogen chloride), P K (Phenol). Monodora myristica are Mo L (Molybdenum), Ag L (Silver iodide), C K (Cyanogen chloride), P K (Phenol), Mg K (Magnesium). Piper guineense are Ag L (Silver iodide), Ci K (Potassium chloride), C K (Cyanogen chloride), P K (Phenol). The seeds show that the AgNP<sub>S</sub> of CA and MM has a better antioxidant activity than the methanol of CA and MM, while the PG methanol has a better activity than the AgNP<sub>S</sub> PG. The control (Catechin and Galic acid) has a slight overall better DPPH activity than the AgNP<sub>S</sub>. It is important to note that there is a concentration dependency in CA, MM AgNP<sub>S,</sub> PG methanol respectively. Notably, at CA methanol, the conc. at 125 was higher than the conc. at 250. Hence, there is need to create a great part in using plant samples for making tabulated or capsulated drugs for treatment of diseases and using plant silver nanoparticles to develop a healthy food/drug preservative package material “smart packaging” that will enhance shelf-life.展开更多
In this study we establish the probability density function of the square transformed left-truncated N(1,σ2) error component of the multiplicative time series model and the functional expressions for its mean and var...In this study we establish the probability density function of the square transformed left-truncated N(1,σ2) error component of the multiplicative time series model and the functional expressions for its mean and variance. Furthermore the mean and variance of the square transformed left-truncated N(1,σ2) error component and those of the untransformed component were compared for the purpose of establishing the interval for σ where the properties of the two distributions are approximately the same in terms of equality of means and normality. From the results of the study, it was established that the two distributions are normally distributed and have means ≌1.0 correct to 1 dp in the interval 0 σ , hence a successful square transformation where necessary is achieved for values of σ such that 0 σ .展开更多
Fresh leaves of Zapoteca portoricensis are used in Eastern Nigeria for management/treatment of various disorders without any scientific basis. Hepatoprotective and antioxidant properties in albino rats, and phytochemi...Fresh leaves of Zapoteca portoricensis are used in Eastern Nigeria for management/treatment of various disorders without any scientific basis. Hepatoprotective and antioxidant properties in albino rats, and phytochemical composition of distilled water and ethanol leaf extracts were studied. Fifty-five animals were placed in eleven groups (A-K) of five in each. Different doses (100, 200, 400 and 600 mg/kg body weight) of the extracts, 20 mg/kg body weight of vitamin C (standard antioxidant) and distilled water were orally administered to groups A-H, I and J-K respectively for six consecutive days. On the seventh day, 2.5 ml/kg body weight of carbon tetrachloride (CCl4) was given intraperitoneally to groups A-J, while group K received distilled. Serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and gamma glutamyltransferase (GGT) were used to study hepatoprotective effect. Malondialdehyde (MDA), superoxide dismutase (SOD) and catalase (CAT) levels in the liver were monitored to assess antioxidant activity. Phytochemical analysis revealed the presence of alkaloids, tannins, saponins, flavonoids, anthraquinones, terpenoids and cardiac glycosides in the extracts. Pretreatment of the rats with the extracts produced a significant decrease (p < 0.05) in ALT, AST, GGT and MDA, while the activity of SOD and CAT increased significantly (p < 0.05) relative to the positive control. These results, which were dose-dependent, are indicative of hepatoprotective and antioxidants potentials of the extracts, and may be due to their phytoconstituents.展开更多
This study investigated the relationship between topographic information and trends in rainfall in Aba urban, South Eastern Nigeria. GIS data were applied to generate topographical information on?runoff characteristic...This study investigated the relationship between topographic information and trends in rainfall in Aba urban, South Eastern Nigeria. GIS data were applied to generate topographical information on?runoff characteristics, the slope, the contour, the aspect and the digital elevation model. The Mann-Kendall Trend was applied to the rainfall data to show if a monotonic increase, decrease or stability trend exist for the rainfall data of Aba metropolis for the period 2000-2010. Results showed that virtually all parts of Aba were liable to floods expect Ogbor hill axis. The flood vulnerability map indicated that 71.65% of the study area was vulnerable to flood. Rainfall trend showed a decrease in six out of the ten year period. Since within this period, flood intensity had generally remained the same, we concluded that topography, poor drainage infrastructure and non-compliance with building, planning and environmental regulations rather than rainfall trend were the key cause of flood problem in the study area.展开更多
We present the evaluation of four Eco-friendly corrosion inhibitors for the corrosion mitigation of mild steel in acid media. The corrosion inhibition of mild steel by ethanol extracts from Viscum album (EEVA) and som...We present the evaluation of four Eco-friendly corrosion inhibitors for the corrosion mitigation of mild steel in acid media. The corrosion inhibition of mild steel by ethanol extracts from Viscum album (EEVA) and some of its isolated phytochemical components;phytates extract (PEVA), saponins extract (SEVA), and flavonoids extracts (FEVA) have been studied using gravi-metric and gasometric techniques. The results of the study reveal that these ecofriendly and benign extracts function as good inhibitors for mild steel corrosion in sulphuric acid. Inhibition efficiency of the extracts increases with inhibitor concentration and temperature rise. The trend of inhibition efficiency in lower inhibitor concentration is EEVA > PEVA > SEVA > FEVA and at higher concentration, the order was SEVA > PEVA > EEVA > FEVA. The presence of the plant extracts decreases the corrosion activation energy in the solution which indicates chemical adsorption mechanism. The adsorption of the components of the extracts is consistent with Temkin isotherm. The interaction between the isolated extracts is synergistic at lower inhibitor concentration and antagonistic at higher concentrations. The Kads values for PEVA and SEVA are higher than those of EEVA and FEVA. This implies that PEVA and SEVA are more efficiently adsorbed on the mild steel surface.展开更多
Background: Congenital anomalies of the kidney and urinary tract (CAKUT) are a well-documented risk factor for the development of urinary tract infection (UTI) in children. Prevention of UTI in this group of patients ...Background: Congenital anomalies of the kidney and urinary tract (CAKUT) are a well-documented risk factor for the development of urinary tract infection (UTI) in children. Prevention of UTI in this group of patients is advocated due to their increased risk of renal scarring, hypertension and end stage kidney failure. Methods: A 10-year retrospective review of CAKUT patients at the Johannesburg Academic Hospital, who were placed on prophylactic antibiotics over a certain period was done. The rate of UTI, the types of causative organisms isolated and the efficacy of prophylactic antibiotics in preventing UTI were documented. Results: Thirty-six (36) out of 134 patients had been started on prophylactic antibiotics after the diagnosis of CAKUT was made. There was a statistically significant association between the use of prophylactic antibiotics and the rate of UTI (p Conclusion: Antibiotic prophylaxis was very effective in decreasing the rate of UTI in our cohort of patients with CAKUT.展开更多
The extraction of Cobalt(II) from aqueous solution using 1-phenyl-3-methyl-4-(p-nitrobenzoyl)pyrazolone (HPMNP) in various organic solvents was studied as a function of pH and extractant concentration. Extraction into...The extraction of Cobalt(II) from aqueous solution using 1-phenyl-3-methyl-4-(p-nitrobenzoyl)pyrazolone (HPMNP) in various organic solvents was studied as a function of pH and extractant concentration. Extraction into organic chloroform phase was more efficient than with any other solvent. The extraction equilibrium constant was found to be log Kex= -7.04. Optimum conditions for extraction of Co(II) exist at pH of between 5.5 and 7.0, ionic strength of 0.3 Mand constant extractant concentration of 0.02 M. Shaking the organic Co(II) chelate complex with 0.2 Macid strips the Co(II) ions into the aqueous phase. It was established that Co(II) complex extracted is of composition, Co(PMNP)2.展开更多
文摘The study investigates cybersecurity challenges in Nigerian deposit money banks (DMBs) with a focus on proactive measures taken by banks and customers to overcome these challenges. The research design employs a descriptive approach and census sampling, with data collected from staff of selected DMBs using questionnaires. Data analysis was conducted using SPSS, and findings indicate that the major challenges confronting cybersecurity in banks were pharming, identity theft, SIM Swap fraud, Skimming/Website cloning and Smishing/Vishing. The major factors responsible were found to include loopholes in the banks’ internal control system, insider abuse by bank staff, ignorance and lack of security consciousness among the banking customers etc. it was found that banks implement measures such as encryption, password changes, and blocking unsolicited messages to mitigate cybersecurity risks. The study concludes with recommendations for continuous security updates, internal control reviews, and customer education campaigns. While the study addresses an important topic, there are areas where clarity, depth, and methodological rigor could be strengthened for a more robust contribution to the field.
文摘The study is focused on agricultural credit sources and determinants of credit acquisition by farmers in ldemili local government area of Anambra State, Nigeria with specific objectives to: describe socio-economic characteristics of rural farmers; identify sources of agricultural credit available to rural farmers; determine socio-economic factors that influence agricultural credit acquisition of farmers; ascertain reasons for any credit misappropriation and identify problems that constrain farmers from agricultural credit acquisition. Ninety farmers were randomly selected by multi stage random sampling technique. Semi-structured questionnaire was used to elicit data for the study. Descriptive statistics and multiple regression model were used in achieving the objectives. Results indicated that 74.44% of respondents were males with a mean age of 45 years. Majority (76.67%) were married with large house hold sizes. Majority (93.33%) received different level of education, with sources of credit from friends/relatives (30.00%), cooperative societies (43.33%), money lenders (14.44%), and cumulatively from formal sources ((12.22%). The result of the multiple regression analysis revealed age, household size, membership of cooperative societies, marital status, education level, farm size and amount of loan repaid at varied signs and levels as significant predictors of amount of agricultural credit acquired by farmers. The most common reason given among the respondents (55.89%) of those who misappropriated acquired agricultural credit, was meeting nonfood needs of the household. The farmers encountered problems of high interest rate (78.89%), lack of collateral (75.56%), long distance from source of credit (50.00%), poor harvest (37.78%), moratorium (33.33%) and delay in loan approval/disbursement (44.44%) as constraints to acquire credit. The study recommends that the state government should pass policies aimed at providing free educative seminars to all illiterate farmers to teach them possible ways and methods of acquiring credit. To ensure mass attendance to such seminars, little incentives should be given to farmer participants.
文摘<strong>Introduction: </strong>Hepatitis B virus (HBV) infection is a major cause of prenatal death worldwide. Chronic hepatitis B (CHB) infection is associated with an increased risk of cirrhosis, hepatic decomposition, and hepatocellular carcinoma (HCC). <strong>Objective:</strong> This project work surveyed the prevalence of hepatitis B among febrile patients as well as to detect hepatitis B virus in the blood and the stage of the infection of hepatitis B on the affected patients and carrier stage or state of immunity of the affected patients. <strong>Methodology:</strong> A well-designed questionnaire/checklist was used to gather information regarding age, HIV-Status, and sex from 50 febrile patients. 2 ml of blood sample was obtained by venin-puncture using a sterile hypodermic syringe and emptied into a clean dry tube (without anticoagulant) observing the necessary aseptic techniques. The blood was centrifuged and the sera obtained and stored at 2 - 8 c for HBsAg screening. Hepatitis B virus was tested using an<em> in-vitro </em>diagnostic kit called HBsAg one-step rapid test strip. The HBsAg one-step rapid test is a lateral flow chromatographic immunoassay based on the principle of the double antibody-sandwich technique. The membrane is pre-coated with anti-HBsAg antibodies on the test line region of the test. During testing, the serum specimen reacts with the particle coated with anti-HBsAg antibody. The serum moves up with capillary action to react with the coated antibody on the membrane. Then, the colored line (positive) will be generated which shows the presence of the virus. But negative shows absence of the virus. The blood in the test tube was spun using a centrifuge to separate the red cells from the serum. The test pouch, serum, and control were allowed to equilibrate to room temperature before testing. The test strip was removed from the sealed pouch and used immediately. The test strip was immersed vertically into the serum with the arrows pointing towards the serum for about 10 - 15 seconds, without exceeding the maximum line on the test strip. The strip was placed on a non-absorbent flat surface. The time was set and the result read after 15 minutes and recorded. The procedure was repeated for each sample and the results were recorded accordingly. The test is positive when two red lines appear on the test region (T) and control region (C) only. The result is said to be invalid when one line appears on the test region (T) and non on the control region (C) and also when no line appears on both the test region (T) and control region (C). <strong>Results:</strong> After interpretation of the result of the test on fifty patients,<strong> Table 1</strong> shows the age range of the population. The total distribution of subjects concerning age was as follows: 4 out of 50 populations (8%) were observed for the age range of 0 - 10;7 out of 50 (14%) were observed of the age range of 11 - 20;28 out of 50 (56%) were observed for a range of 21 - 30;9 out of 50 (18%) were observed for the age range of 31 - 40;2 out of 50 (4%) were observed at the age range of 21 - 30 with percentage seroprevalence of 4%. There is no significant correlation in the age group concerning percentage seroprevalence (P = 0.05). Also, the sex of the study population as seen in <strong>Table 2</strong> shows that 21 were males and 29 were females. Out of the 21 males population, 3 (14.24%) were positive. In the female population, 5 out of 29 (17.24%) were positive. The prevalence of the population concerning their sex was tested using Pearson’s chi-square and it was concluded that there is no significant relationship between sex and seroprevalence of hepatitis B. <strong>Table 3 </strong>shows the HIV of the study population and it shows that 6 out of 14 HIV positive patients (42.56%) were positive and 3 out of 36 HIV-negative patients (4.55%)) were positive. The prevalence of the population concerning HIV status was tested using Pearson’s chi-square and it was concluded that there is a significant association between HIV status and seroprevalence of hepatitis B. <strong>Conclusion: </strong>In conclusion, this study shows that there is a low prevalence of hepatitis B among febrile patients at the study area, hence limiting fever as a major determinant of hepatitis B infection. Considering the high risk of HBV in HIV co-infected patients, there is a need for the screening of HIV-infected patients for hepatitis B and appropriate therapy followed up on possible HBV-HIV co-infected patients. Appropriate preventive measures especially vaccination against hepatitis B virus should be encouraged among the susceptible population.
文摘Background: Healthcare workers are challenged by an imposing group of occupational hazards. These hazards include exposure to biological and non-biological hazards like ionizing radiation, stress, injury, infectious agents, and chemicals. The aim of this study was to assess common occupational hazards among health workers at the Department of Health Services (DHS), Federal University of Technology, Owerri. Methods: A hospital-based cross-sectional study design was employed for the study, and a self-administered questionnaire was used for data collection. The SPSS Version 22.0 software was used for the analysis of the descriptive statistics obtained from the study. This study included both clinical and non-clinical health workers. A purposive sampling technique was used in recruiting a total of 94 respondents who participated in the study from September 2020 to April 2021. Results: A total of 94 respondents who participated in the study and among the participants, 33.3% (31) of the respondents were aged 31 - 40 years, and the majority of the health workers, 43.6% (41) had stayed between 1 - 5 years. Also, 92.6% (87) of the health workers have heard of occupational hazards. The study showed that 84.0% (79) of health workers had good knowledge of common occupational hazards. Biological hazards among health workers are 47.9% (45) cuts and wounds, 29.8% (28) direct contact with contaminated specimens/hazardous materials, and 26.6% (26) sharp related injuries, while for non-biological hazards, 44.7% (42) have slipped, tripped or fallen, and 35.1% (33) have been stressed. Common safety measures include 86.2% (81) washing their hands regularly;78.7% (74) using hand gloves;and 85.1% (80) agreeing they use face masks. Conclusion: Despite good knowledge of occupational hazards, participants at DHS were faced with certain hazards. It is recommended that the university, government, and policymakers revise and implement actions to provide health workers at DHS with equipment to encourage safety in work activity.
文摘Nurses must deliver infusions as prescribed since too slow or fast a dose could be deleterious to patients. Nurses experience challenges with infusion dose calculations, making them vulnerable to errors. The research team examined drop factor and infusion dose calculation discrepancies among nurses in southern Nigeria. Five university teaching hospitals were involved in this cross-sectional study conducted in 2019. To establish the drop factor of commonly available macro drip sets, the team randomly sourced 25 macro drip sets from the hospitals’ pharmacies. A sample of 291 nurses was selected using a proportionate random sampling technique. The team collected data using the Adult Infusion Dose Calculation Quiz and analyzed it at a 5% significance level. Twenty (80%) of the sampled macro drip sets displayed a drop factor value of 20 drops per milliliter (gtt/ml) on their packaging. When measured experimentally, 25 (100%) of the macro drip sets delivered exactly 20 gtt/ml. Only 36 (12.4%) respondents calculated macro drip infusion doses using the correct drop factor of 20 gtt/ml. Non-attendance of infusion administration training updates significantly increased the risk of error by 38% (p ≤ 0.001). In conclusion, the drop factor of macro drip sets used in southern Nigeria is 20 gtt/ml;nurses were prone to infusing patients at a lower dose than prescribed. Special training in infusion therapy might remedy this concern.
文摘Problem Statement: Malaria’s global impact necessitates effective treatments, like dihydroartemisinin-piperaquine (DHA/PQP), though safety concerns, notably drug-induced cardiotoxicity (DICT), persist. A knowledge gap exists regarding DHA/PQP’s cardiac effects, warranting a comprehensive investigation. Approach: This study aimed to assess KROSH (DHA/PQP) impact on albino rat heart histology, examining structural changes and potential cardiotoxicity. 40 albino rats were grouped by KROSH dosage and duration, monitored for weight changes, and heart tissues were examined using hematoxylin and eosin (H & E) staining. Statistical analysis compared to control and treated groups. Results: KROSH administration led to varying rat weight effects, yet not statistically significant. Histological analysis revealed dose and duration-dependent cardiac tissue alterations, including distortion, adipose deposits, artery hypertrophy, fibrosis, and necrosis. These contrasts with prior research documenting DHA/PQP’s non-toxic effects. Conclusion/Recommendation: This study highlights potential KROSH (DHA/PQP) cardiotoxicity concerns through histological changes, underscoring the need for further research into underlying mechanisms and human health implications. Given DHA/PQP’s wide use, these findings should inform safety evaluations and administration practices.
文摘Background: This study aimed to assess the toxicity of Irvingia gabonensis leaf extracts in albino rats and investigate their effects on body weight, liver function parameters, and renal function parameters. The research specifically compared the outcomes of aqueous and ethanol extraction methods. Methods: Acute toxicity was evaluated by administering a single oral dose of Irvingia gabonensis leaf extracts to rats and monitoring them for 24 hours and during a 14-day observation period. Sub-acute toxicity was assessed through a 28-day administration of the leaf extract. Body weight changes, liver function parameters, and renal function parameters were measured and compared among treatment groups. Results: No signs of toxicity or mortality were observed in rats treated with Irvingia gabonensis leaf extracts obtained through either aqueous or ethanol extraction methods. The calculated lethal dose required to cause mortality in 50% of the tested animals (LD<sub>50</sub>) exceeded 5000 mg/kg body weight. Oral administration of the leaf extract at doses of 400 and 800 mg/kg body weight did not induce any observable signs of toxicity or adverse effects during the 28-day study period. Male and female albino rats treated with the leaf extract showed significant weight gains compared to the control group. Higher doses (800 mg/kg) of both aqueous and ethanol extracts led to increased levels of total protein, albumin, and globulin in male albino rats, with the ethanol extract exhibiting a more pronounced effect. The administration of the ethanol extract, particularly at the lower dose (400 mg/kg), resulted in decreased levels of liver enzymes (AST, ALT, and ALP), suggesting potential liver protective properties. Additionally, bilirubin levels, a marker of liver dysfunction, were significantly reduced in all treatment groups, with the lowest levels observed in the groups receiving higher doses of both aqueous and ethanol extracts. The administration of Irvingia gabonensis leaf extracts did not significantly affect renal function parameters in both male and female albino rats. Conclusion: Irvingia gabonensis leaf extracts obtained through aqueous and ethanol extraction methods showed no acute or sub-acute toxicity in albino rats. The extracts demonstrated potential beneficial effects on liver function parameters, particularly at higher doses. However, further research is needed to validate these findings and determine the optimal dosage for potential therapeutic applications in humans.
文摘Background: The burden of COVID-19 and human immunodeficiency virus (HIV) are some of the major and persistent global health challenges of the twenty-first century. HIV and COVID-19 are expected to overlap in high HIV-burden countries, posing several public health challenges as a result. Prisons are overcrowded, have limited space for social distancing and have inadequate ventilation systems, making it difficult to contain the spread of COVID-19 in addition to the high-risk behaviours of inmates which contribute to the spread of HIV within these facilities. This study aimed to determine the prevalence of COVID-19 among inmates in a prison facility with a relatively high HIV burden in Port Harcourt, Nigeria;investigating potential risk factors and co-infection with HIV. Methodology: The study employed a descriptive cross-sectional study design sampling 200 inmates from the Port Harcourt Maximum Security Custodial Centre from July to December 2022. A well-structured questionnaire was administered via interviews in addition to screening for HIV-1/2 antibodies as well as COVID-19 antigens using rapid diagnostic test kits. Descriptive statistics and chi-square were carried out on the GraphPad Prism 9 software with statistical significance defined as a p-value of less than 0.05 at a 95% confidence interval. Result: The prevalence of HIV from the current study was 6.5%, COVID-19 prevalence was reported to be 12.5% while HIV/COVID-19 co-infection was 1.5% The duration of incarceration, face mask use, frequent visitations and vaccination against COVID-19 were found to be significantly associated with the prevalence of COVID-19 in the studied population (p Conclusion: The current study reports a relatively high prevalence of HIV and COVID-19 among the inmates in the study area. It becomes expedient for the administrators of the correctional facility to properly screen new inmates for COVID-19, quarantine and manage cases, as well as provide them with personal protective equipment such as face masks. In-person visitation should be balanced with measures to prevent the spread of the infection, and mass vaccination campaigns should be promoted. Improving access to HIV screening and therapy for all prisoners should be prioritised to identify and manage the incidence of HIV early, reducing the risk of transmission, mitigating comorbidities and improving health outcomes.
文摘Pawpaw and lime juices were blended to produce mixed pawpaw/lime juice samples in the ratios of 90:10, 80:20, 70:30, 60:40 and 50:50) v/v giving samples A, B, C, D and E respectively. The moisture, mineral and vitamin contents, as well as the physical, microbiological and sensory qualities of the individual juices and blended samples were evaluated. While lime juice had higher moisture, calcium and vitamin C with values of 97.90%, 2.21 mg/100 g and 67.47 mg/100 g as compared to pawpaw juice with 92.96%, 1.53 mg/100 g and 35.49 mg/100 g respectively;the pawpaw juice had higher ash, phosphorus and vitamin A contents, with values of 3.12%, 54.97 mg/100 g and 5.90 IU/100 g as against 2.84%, 29.53% and 0.16% for lime juice respectively. While there was a general increase in moisture, calcium and vitamin C contents with blending, ash, phosphorus and vitamin A contents increased with increase in lime. The total solids content and specific gravity of pawpaw juice were remarkably higher at 7.04% and 1.15 g/m3 compared to 2.09% and 1.09 g/m3 respectively for lime juice. However, lime juice had a higher titratable acidity, while recording a lower pH of 2.89 as compared to 5.36 for pawpaw juice. The Total Viable Count (TVC) of lime juice was much lower (2.33 × 105 CFU/ml) than that of pawpaw juice (5.33 × 106 CFU/ml). There was significant difference (p < 0.05) in all the sensory parameters evaluated. Generally, there was an increase in the scores of each parameter from sample A to B and then a decline through to sample E. Sample B (80:20) mixed pawpaw/lime juice was most preferred, while sample E (50:50) was least preferred.
文摘Marshlands are important ecosystem for living organisms. The Southern Iraqi Marshland is the central habitat for freshwater fish, provides habitat for important populations of wildlife and serves as a source of income for native economies through reed harvesting. Studies have shown that variability in climate and human-induced factors affects the spatial dynamics of marsh ecosystems. This study assessed wetland changes in the Southern Iraqi Marshlands using Remotely Sensed Data from 1986 to 2019 using Landsat satellite imagery for four epochs: 1986, 2000, 2010 and 2019. To achieve this, thirty (30) pixels were obtained in selected land cover theme and their signatures were merged into one class. Furthermore, the selected pixels were recoded and merged into ten (10) land cover classes. The multi-layer classes created were shallow water, deep water, dense marsh, medium marsh, sparse marsh, dense vegetation, medium vegetation, sparse vegetation, dry soil and wet soil. The areal extents of the land cover types were calculated for 1986, 2000, 2010 and 2019. Normalized Difference Vegetation Index (NDVI) differencing was also carried in order to highlight trends in vegetation from 1986 to 2019. The study correlated historical trends of human activities as a central factor in the degradation of marshland (by 16.25%) from 1986 to 2000. However, by the year 2000 to 2010, there was an 11.36% increase in the total marshland area, which remained almost unchanged between 2010 and 2019. In 1986, NDVI was relatively stable at 0.73 in the Al-Hammar and Al-Hwaizeh Marsh. However, by 2000, the areas of dense vegetation cover reduced drastically by over 90%. In 2010, the NDVI index indicated trends of increasing water body and an outward cluster of healthier vegetation continuing to 2019.
文摘This study explores the potentials of employing an Organic Rankine Cycle (ORC) system with variable inlet guide vanes (VIV) turbine geometry designed on a GT-Suite platform for effective exhaust heat recovery (EHR) application onboard passenger vehicles. The ORC model simulation was based on vehicle speed mode using R245fa as working fluid to assess the thermal performance of the ORC system when utilizing modified turbine geometry. Interestingly, the model achieved a very improved performance in contrast to the model without a modified turbine configuration. The results revealed the average 2.32 kW ORC net output, 4.93% thermal efficiency, 6.1% mechanical efficiency, and 5.0% improved brake specific fuel consumption (BSFC) for the developed model. As determined by the performance indicators, these promising results from the model study show the prospect of EHR technology application in the transportation sector for reduction in exhaust emissions and fuel savings.
文摘Background: Oedema, a constant feature of childhood nephrotic syndrome can be severe, enough to cause respiratory embarrassment. It can also be refractory to diuretic monotherapy. In such cases, combination of salt poor albumin (SPA) infusion and diuretics has remained the best treatment option. However, the cost of SPA has made it practically unavailable in resource-poor settings. It becomes a therapeutic dilemma when nephrotic syndrome patients of financially-constrained caregivers present with refractory anasarca in a resource-poor settings. Case review: We present a seven-year-old boy with relapsed steroid sensitive nephrotic syndrome who presented to Abia State University Teaching Hospital Aba, in respiratory distress with anasarca and a weight of 58 kilograms. SPA could not be accessed due to financial constraints. A decision to use fresh whole blood in the place of SPA, in combination with frusemide, achieved a lifesaving diuresis and regression of the anasarca. Conclusion: Whole blood is a good alternative for the treatment of refractory oedema in children with nephrotic syndrome in resource poor settings.
文摘Multilingualism and multiculturalism have become so characteristic of our times that it is hard to come by a literary work that is strictly monolingual. Languages in contact influence each other in various ways. One language could be more influential than the other as a result of linguistic and non-linguistic factors. A language that is documented and enjoys a more privileged political, economic, cultural, or religious position is likely to be more influential than another language that lacks these qualities. Languages in contact often borrow words from each other though a language that is considered to be more prestigious than another is more likely to be the donor language less prestigious one. Loanwords are therefore common among languages in contact. Intercultural literary communication is mostly effected through translation. Due to Africa's colonial experience, literary translation practice in Africa often involves European languages, Arabic, and indigenous African languages. In Nigeria, the languages that have played significant roles in literary translation include English, French, German, Arabic, and indigenous Nigerian languages. Franz Kafka's Brief an den Vater which was written in German has been translated into English as Letter to His Father by Ernest Kaiser and Eithne Wilkins and into Igbo as Soro Okwu m maobu Leta (Ndi) Nna by Felicia Ibemesi. This paper sets out to study loanwords in the English and Igbo translations from a target reader's perspective
文摘The antioxidant of seeds was carried out using extracts from methanol and Silver Nanoparticles from the spice. The SEM shows the shapes, dispersion and agglomeration of the sample, while the EDX confirms the SEM and the presence of some compounds. The FT-IR reveals the AgNP<sub>s</sub> capping and reducing the particular biomolecule from the functional group for identification. Compounds found in the FT-IR seeds of Capsicum annum are Ag L (Silver iodide), C K (Cyanogen chloride), P K (Phenol). Monodora myristica are Mo L (Molybdenum), Ag L (Silver iodide), C K (Cyanogen chloride), P K (Phenol), Mg K (Magnesium). Piper guineense are Ag L (Silver iodide), Ci K (Potassium chloride), C K (Cyanogen chloride), P K (Phenol). The seeds show that the AgNP<sub>S</sub> of CA and MM has a better antioxidant activity than the methanol of CA and MM, while the PG methanol has a better activity than the AgNP<sub>S</sub> PG. The control (Catechin and Galic acid) has a slight overall better DPPH activity than the AgNP<sub>S</sub>. It is important to note that there is a concentration dependency in CA, MM AgNP<sub>S,</sub> PG methanol respectively. Notably, at CA methanol, the conc. at 125 was higher than the conc. at 250. Hence, there is need to create a great part in using plant samples for making tabulated or capsulated drugs for treatment of diseases and using plant silver nanoparticles to develop a healthy food/drug preservative package material “smart packaging” that will enhance shelf-life.
文摘In this study we establish the probability density function of the square transformed left-truncated N(1,σ2) error component of the multiplicative time series model and the functional expressions for its mean and variance. Furthermore the mean and variance of the square transformed left-truncated N(1,σ2) error component and those of the untransformed component were compared for the purpose of establishing the interval for σ where the properties of the two distributions are approximately the same in terms of equality of means and normality. From the results of the study, it was established that the two distributions are normally distributed and have means ≌1.0 correct to 1 dp in the interval 0 σ , hence a successful square transformation where necessary is achieved for values of σ such that 0 σ .
文摘Fresh leaves of Zapoteca portoricensis are used in Eastern Nigeria for management/treatment of various disorders without any scientific basis. Hepatoprotective and antioxidant properties in albino rats, and phytochemical composition of distilled water and ethanol leaf extracts were studied. Fifty-five animals were placed in eleven groups (A-K) of five in each. Different doses (100, 200, 400 and 600 mg/kg body weight) of the extracts, 20 mg/kg body weight of vitamin C (standard antioxidant) and distilled water were orally administered to groups A-H, I and J-K respectively for six consecutive days. On the seventh day, 2.5 ml/kg body weight of carbon tetrachloride (CCl4) was given intraperitoneally to groups A-J, while group K received distilled. Serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and gamma glutamyltransferase (GGT) were used to study hepatoprotective effect. Malondialdehyde (MDA), superoxide dismutase (SOD) and catalase (CAT) levels in the liver were monitored to assess antioxidant activity. Phytochemical analysis revealed the presence of alkaloids, tannins, saponins, flavonoids, anthraquinones, terpenoids and cardiac glycosides in the extracts. Pretreatment of the rats with the extracts produced a significant decrease (p < 0.05) in ALT, AST, GGT and MDA, while the activity of SOD and CAT increased significantly (p < 0.05) relative to the positive control. These results, which were dose-dependent, are indicative of hepatoprotective and antioxidants potentials of the extracts, and may be due to their phytoconstituents.
文摘This study investigated the relationship between topographic information and trends in rainfall in Aba urban, South Eastern Nigeria. GIS data were applied to generate topographical information on?runoff characteristics, the slope, the contour, the aspect and the digital elevation model. The Mann-Kendall Trend was applied to the rainfall data to show if a monotonic increase, decrease or stability trend exist for the rainfall data of Aba metropolis for the period 2000-2010. Results showed that virtually all parts of Aba were liable to floods expect Ogbor hill axis. The flood vulnerability map indicated that 71.65% of the study area was vulnerable to flood. Rainfall trend showed a decrease in six out of the ten year period. Since within this period, flood intensity had generally remained the same, we concluded that topography, poor drainage infrastructure and non-compliance with building, planning and environmental regulations rather than rainfall trend were the key cause of flood problem in the study area.
文摘We present the evaluation of four Eco-friendly corrosion inhibitors for the corrosion mitigation of mild steel in acid media. The corrosion inhibition of mild steel by ethanol extracts from Viscum album (EEVA) and some of its isolated phytochemical components;phytates extract (PEVA), saponins extract (SEVA), and flavonoids extracts (FEVA) have been studied using gravi-metric and gasometric techniques. The results of the study reveal that these ecofriendly and benign extracts function as good inhibitors for mild steel corrosion in sulphuric acid. Inhibition efficiency of the extracts increases with inhibitor concentration and temperature rise. The trend of inhibition efficiency in lower inhibitor concentration is EEVA > PEVA > SEVA > FEVA and at higher concentration, the order was SEVA > PEVA > EEVA > FEVA. The presence of the plant extracts decreases the corrosion activation energy in the solution which indicates chemical adsorption mechanism. The adsorption of the components of the extracts is consistent with Temkin isotherm. The interaction between the isolated extracts is synergistic at lower inhibitor concentration and antagonistic at higher concentrations. The Kads values for PEVA and SEVA are higher than those of EEVA and FEVA. This implies that PEVA and SEVA are more efficiently adsorbed on the mild steel surface.
文摘Background: Congenital anomalies of the kidney and urinary tract (CAKUT) are a well-documented risk factor for the development of urinary tract infection (UTI) in children. Prevention of UTI in this group of patients is advocated due to their increased risk of renal scarring, hypertension and end stage kidney failure. Methods: A 10-year retrospective review of CAKUT patients at the Johannesburg Academic Hospital, who were placed on prophylactic antibiotics over a certain period was done. The rate of UTI, the types of causative organisms isolated and the efficacy of prophylactic antibiotics in preventing UTI were documented. Results: Thirty-six (36) out of 134 patients had been started on prophylactic antibiotics after the diagnosis of CAKUT was made. There was a statistically significant association between the use of prophylactic antibiotics and the rate of UTI (p Conclusion: Antibiotic prophylaxis was very effective in decreasing the rate of UTI in our cohort of patients with CAKUT.
文摘The extraction of Cobalt(II) from aqueous solution using 1-phenyl-3-methyl-4-(p-nitrobenzoyl)pyrazolone (HPMNP) in various organic solvents was studied as a function of pH and extractant concentration. Extraction into organic chloroform phase was more efficient than with any other solvent. The extraction equilibrium constant was found to be log Kex= -7.04. Optimum conditions for extraction of Co(II) exist at pH of between 5.5 and 7.0, ionic strength of 0.3 Mand constant extractant concentration of 0.02 M. Shaking the organic Co(II) chelate complex with 0.2 Macid strips the Co(II) ions into the aqueous phase. It was established that Co(II) complex extracted is of composition, Co(PMNP)2.