Patient Migration for Hospital Utilization: Case of Iran

Introduction: Adequate information about patient using health care facilities is a critical element in planning activities and allocation resources in health sector. In Iran, with performing family physician plan and attempt to reform referral system, the study of mobility of patients between regions (patient migration) has more importance. The aims of the study are: 1) to describe patients’ migration across cities of Iranian Kerman province;2) to analyze the role of possible determinants affecting the mobility flows. Methodology: using hospital inpatient records of all public hospitals around Kerman province during 2011, we run logit models that compare patients who were admitted in hospital and received health services in cities where they lived and patients received them out of their local hospitals. We studied 21 patient groups according to ICD10 chapters (Appendix 1) to compute the effect of geographic distance, kind of insurance, number of physiccians involved, hospital bed and patient demographic factors. Results: About 40 percent of hospital admissions in Kerman are emigrant patients that quality or quantity of local provided services didn’t satisfy. Constant negative coefficients of geographic distance, hospitals physician and bed and positive coefficients for insurance in all groups do not show any difference in patient migration, between groups. Discussion: According to results of this research, existence of local services, distance, kind of illness and other factors are not more important than patients’ feeling about services in their migration. Paying no attention to this reality in planning health system reforms, especially referral systems, leads to important problems for health system in equity, patient satisfaction and finance aspects.

Conformational Folding Activates Photoinduced Electron Transfer

Photoinduced electron transfer(PET)is a critical process in many functional materials,underpinning various technological applications(i.e.,fluorescent probes and photocatalysts).Despite its signifi-cance,the detailed structural dynamics of PET,particularly during the excited state,remain poorly understood.This study investigates the mechanisms of conformational folding and their implications for activating PET in molecular systems characterized by a fluorophore-spacer-receptor configuration.We demonstrate that traditional computational models,primarily based on frontier molecular orbitals,often fall short in capturing these conformational dynamics,leading to inadequate explanations of PET phenomena.With the incorporation of conformational folding,our computational model has achieved excellent agreement with experimental data,thereby resolving several long-standing debates on PET mechanisms.This mechanistic advancement not only deepens our understanding of PET but also opens new avenues for designing advanced functional materials.We have thus successfully demonstrated the imaging of lysosomes in live cells using a PET probe.

Structural Design Optimization Using Isogeometric Analysis: A Comprehensive Review

Isogeometric analysis(IGA),an approach that integrates CAE into conventional CAD design tools,has been used in structural optimization for 10 years,with plenty of excellent research results.This paper provides a comprehensive review on isogeometric shape and topology optimization,with a brief coverage of size optimization.For isogeometric shape optimization,attention is focused on the parametrization methods,mesh updating schemes and shape sensitivity analyses.Some interesting observations,e.g.the popularity of using direct(differential)method for shape sensitivity analysis and the possibility of developing a large scale,seamlessly integrated analysis-design platform,are discussed in the framework of isogeometric shape optimization.For isogeometric topology optimization(ITO),we discuss different types of ITOs,e.g.ITO using SIMP(Solid Isotropic Material with Penalization)method,ITO using level set method,ITO using moving morphable com-ponents(MMC),ITO with phase field model,etc.,their technical details and applications such as the spline filter,multi-resolution approach,multi-material problems and stress con-strained problems.In addition to the review in the last 10 years,the current developmental trend of isogeometric structural optimization is discussed.

Buoyant Marangoni convection of nanofluids in square cavity

The buoyant Marangoni convection heat transfer in a differentially heated cavity is numerically studied. The cavity is filled with water-Ag, water-Cu, water-Al2O3, and water-TiO2 nanofiuids. The governing equations are based on the equations involving the stream function, vorticity, and temperature. The dimensionless forms of the governing equations are solved by the finite difference （FD） scheme consisting of the alternating direction implicit （ADI） method and the tri-diagonal matrix algorithm （TDMA）. It is found that the increase in the nanoparticle concentration leads to the decrease in the flow rates in the secondary cells when the convective thermocapillary and the buoyancy force have similar strength. A critical Marangoni number exists, below which increasing the Marangoni number decreases the average Nusselt number, and above which increasing the Marangoni number increases the average Nusselt number. The nanoparticles play a crucial role in the critical Marangoni number.

Synthesis, Structure and Quantum Mechanical Calculations of Methyl 2-(5-((Quinolin-8-yloxy)-methyl)-1,3,4-oxadiazol-2-ylthio)-acetate

The title compound was synthesized by the base catalyzed reaction of 5-（（quinolin- 8-yloxy）methyl）-1,3,4-oxadiazole-2（3H）-thione with methyl chloroacetate. The structure was supported by the spectroscopic data and unambiguously confirmed by single-crystal X-ray diffraction studies. It crystallizes from a methanol solution in the triclinic space group Pi with unit cell dimensions a = 7.4509（9）, b = 10.2389（12）, c = 12.2299（15）A, a = 74.771（2）, β = 77.956（2）, 7 = 69.263（2）°, V = 834.98（17） A3 and Z = 2. In order to gain some valuable insights into the molecular structure, the quantum mechanical calculations were performed using both HF and time-dependent density functional theory at the B3LYP/6-31G（d,p） level. The molecular geometry from X-ray determination of the title compound in the ground state has been compared using the Hartree-Fock （HF） and density functional theory （DFT） with the 6-31G（d） basis set. The calculated results show that the DFT and HF can well reproduce the structure of the title compound. The energetic behavior of the title compound was examined using the B3LYP method with the 6-31G（d） basis set. The harmonic vibrational frequencies calculated have been compared with the experimental FTIR and FT-Raman spectra. The restricted Hartree-Fock and density functional theory-based nuclear magnetic resonance （NMR） calculation procedure was also performed, and it was used for assigning the 13C and 1H NMR chemical shifts of the title compound. Moreover, molecular electrostatic potential and thermodynamic parameters of the title compound were investigated by theoretical calculations.

Large shear rate behavior for the Hébraud-Lequeux model

The Hébraud-Lequeux model is a model describing the flow of soft glassy material in a simple shear flow configuration.It is given by a kinetic/Fokker-Planck-type equation whose coefficients depend on the shear rate of the experiment.In this paper we want to study what happens to the stationary solutions of this model when the shear rate is asymptotically large.In order to do that,we expand the solution of the equation using singular perturbation tools.In the end,we rigorously prove the estimate of Hébraud and Lequeux that the material asymptotically behaves as a Newtonian fluid.

Large shear rate behavior for the Hebraud-Lequeux model Dedicated to the NSFC-CNRS Chinese-French summer institute on fluid mechanics in 2010

The H@braud-Lequeux model is a model describing the flow of soft glassy material in a simple shear flow configuration. It is given by a kinetic/Fokker-Planck-type equation whose coefficients depend on the shear rate of the experiment. In this paper we want to study what happens to the stationary solutions of this model when the shear rate is asymptotically large. In order to do that, we expand the solution of the equation using singular perturbation tools. In the end, we rigorously prove the estimate of Hebraud and Lequeux that the material asymptotically behaves as a Newtonian fluid.