A Survey of Lung Nodules Detection and Classification from CT Scan Images

In the contemporary era,the death rate is increasing due to lung cancer.However,technology is continuously enhancing the quality of well-being.To improve the survival rate,radiologists rely on Computed Tomography(CT)scans for early detection and diagnosis of lung nodules.This paper presented a detailed,systematic review of several identification and categorization techniques for lung nodules.The analysis of the report explored the challenges,advancements,and future opinions in computer-aided diagnosis CAD systems for detecting and classifying lung nodules employing the deep learning(DL)algorithm.The findings also highlighted the usefulness of DL networks,especially convolutional neural networks(CNNs)in elevating sensitivity,accuracy,and specificity as well as overcoming false positives in the initial stages of lung cancer detection.This paper further presented the integral nodule classification stage,which stressed the importance of differentiating between benign and malignant nodules for initial cancer diagnosis.Moreover,the findings presented a comprehensive analysis of multiple techniques and studies for nodule classification,highlighting the evolution of methodologies from conventional machine learning(ML)classifiers to transfer learning and integrated CNNs.Interestingly,while accepting the strides formed by CAD systems,the review addressed persistent challenges.

Automated Grading of Breast Cancer Histopathology Images Using Multilayered Autoencoder

Breast cancer(BC)is the most widely recognized cancer in women worldwide.By 2018,627,000 women had died of breast cancer(World Health Organization Report 2018).To diagnose BC,the evaluation of tumours is achieved by analysis of histological specimens.At present,the Nottingham Bloom Richardson framework is the least expensive approach used to grade BC aggressiveness.Pathologists contemplate three elements,1.mitotic count,2.gland formation,and 3.nuclear atypia,which is a laborious process that witness’s variations in expert’s opinions.Recently,some algorithms have been proposed for the detection of mitotic cells,but nuclear atypia in breast cancer histopathology has not received much consideration.Nuclear atypia analysis is performed not only to grade BC but also to provide critical information in the discrimination of normal breast,non-invasive breast(usual ductal hyperplasia,atypical ductal hyperplasia)and pre-invasive breast(ductal carcinoma in situ)and invasive breast lesions.We proposed a deep-stacked multi-layer autoencoder ensemble with a softmax layer for the feature extraction and classification process.The classification results show the value of the multilayer autoencoder model in the evaluation of nuclear polymorphisms.The proposed method has indicated promising results,making them more fit in breast cancer grading.

ResMHA-Net:Enhancing Glioma Segmentation and Survival Prediction Using a Novel Deep Learning Framework

Gliomas are aggressive brain tumors known for their heterogeneity,unclear borders,and diverse locations on Magnetic Resonance Imaging(MRI)scans.These factors present significant challenges for MRI-based segmentation,a crucial step for effective treatment planning and monitoring of glioma progression.This study proposes a novel deep learning framework,ResNet Multi-Head Attention U-Net(ResMHA-Net),to address these challenges and enhance glioma segmentation accuracy.ResMHA-Net leverages the strengths of both residual blocks from the ResNet architecture and multi-head attention mechanisms.This powerful combination empowers the network to prioritize informative regions within the 3D MRI data and capture long-range dependencies.By doing so,ResMHANet effectively segments intricate glioma sub-regions and reduces the impact of uncertain tumor boundaries.We rigorously trained and validated ResMHA-Net on the BraTS 2018,2019,2020 and 2021 datasets.Notably,ResMHA-Net achieved superior segmentation accuracy on the BraTS 2021 dataset compared to the previous years,demonstrating its remarkable adaptability and robustness across diverse datasets.Furthermore,we collected the predicted masks obtained from three datasets to enhance survival prediction,effectively augmenting the dataset size.Radiomic features were then extracted from these predicted masks and,along with clinical data,were used to train a novel ensemble learning-based machine learning model for survival prediction.This model employs a voting mechanism aggregating predictions from multiple models,leading to significant improvements over existing methods.This ensemble approach capitalizes on the strengths of various models,resulting in more accurate and reliable predictions for patient survival.Importantly,we achieved an impressive accuracy of 73%for overall survival(OS)prediction.