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Solid pseudopapillary tumor of the pancreas:A systematic review of clinical,surgical and oncological characteristics of 1384 patients underwent pancreatic surgery
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作者 Gennaro Mazzarella Edoardo Maria Muttillo +5 位作者 Diego Coletta Biagio Picardi Stefano Rossi Simone Rossi Del Monte Vito Gomes Irnerio Angelo Muttillo 《Hepatobiliary & Pancreatic Diseases International》 SCIE CAS CSCD 2024年第4期331-338,共8页
Background:Pancreatic solid pseudopapillary tumors(SPTs)are rare clinical entity,with low malignancy and still unclear pathogenesis.They account for less than 2%of exocrine pancreatic neoplasms.This study aimed to per... Background:Pancreatic solid pseudopapillary tumors(SPTs)are rare clinical entity,with low malignancy and still unclear pathogenesis.They account for less than 2%of exocrine pancreatic neoplasms.This study aimed to perform a systematic review of the main clinical,surgical and oncological characteristics of pancreatic SPTs.Data sources:MEDLINE/PubMed,Web of Science and Scopus databases were systematically searched for the main clinical,surgical and oncological characteristics of pancreatic SPTs up to April 2021,in accordance with the preferred reporting items for systematic reviews and meta-analyses(PRISMA)standards.Primary endpoints were to analyze treatments and oncological outcomes.Results:A total of 823 studies were recorded,86 studies underwent full-text reviews and 28 met inclusion criteria.Overall,1384 patients underwent pancreatic surgery.Mean age was 30 years and 1181 patients(85.3%)were female.The most common clinical presentation was non-specific abdominal pain(52.6%of cases).Mean overall survival was 98.1%.Mean recurrence rate was 2.8%.Mean follow-up was 4.2 years.Conclusions:Pancreatic SPTs are rare,and predominantly affect young women with unclear pathogenesis.Radical resection is the gold standard of treatment achieving good oncological impact and a favorable prognosis in a yearly life-long follow-up. 展开更多
关键词 Frantz’s tumor PANCREAS Pancreatic neoplasms Pancreatic surgery Solid pseudopapillary tumor
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indocyanine green-based fluorescence imaging in visceral and hepatobiliary and pancreatic surgery:State of the art and future directions 被引量:26
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作者 Gian Luca Baiocchi Michele Diana Luigi Boni 《World Journal of Gastroenterology》 SCIE CAS 2018年第27期2921-2930,共10页
In recent years, the use of fluorescence-guided surgery(FGS) to treat benign and malignant visceral, hepatobiliary and pancreatic neoplasms has significantly increased. FGS relies on the fluorescence signal emitted by... In recent years, the use of fluorescence-guided surgery(FGS) to treat benign and malignant visceral, hepatobiliary and pancreatic neoplasms has significantly increased. FGS relies on the fluorescence signal emitted by injected substances(fluorophores) after being illuminated by ad hoc laser sources to help guide the surgical procedure and provide the surgeon with real-time visualization of the fluorescent structures of interest that would be otherwise invisible. This review surveys and discusses the most common and emerging clinical applications of indocyanine green(ICG)-based fluorescence in visceral, hepatobiliary and pancreatic surgery. The analysis, findings, and discussion presented here rely on the authors' significant experience with this technique in their medical institutions, an up-to-date review of the most relevant articles published on this topic between 2014 and 2018, and lengthy discussions with key opinion leaders in the field during recent conferences and congresses. For each application, the benefits and limitations of this technique, as well as applicable future directions, are described. The imaging of fluorescence emitted by ICG is a simple, fast,relatively inexpensive, and harmless tool with numerous different applications in surgery for both neoplasms and benign pathologies of the visceral and hepatobiliary systems. The ever-increasing availability of visual systems that can utilize this tool will transform some of these applications into the standard of care in the near future. Further studies are needed to evaluate the strengths and weaknesses of each application of ICG-based fluorescence imaging in abdominal surgery. 展开更多
关键词 indocyanine green FLUORESCENCE IMAGING gastrointestinal SURGERY liver SURGERY BILIARY SURGERY pancreatic SURGERY VISCERAL perfusion BILIARY anatomy peritoneal CARCINOMATOSIS
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Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in epithelial ovarian cancer: State of the art 被引量:1
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作者 Ramez N Eskander Luca Ansaloni +1 位作者 Robert E Bristow Federico Coccolini 《World Journal of Obstetrics and Gynecology》 2013年第4期94-100,共7页
Advanced stage epithelial ovarian cancer(EOC) is diffi cult to treat with low overall cure rates. A new strategy combining maximal cytoreductive surgery(CRS) with intraoperative hyperthermic intraperitoneal chemothera... Advanced stage epithelial ovarian cancer(EOC) is diffi cult to treat with low overall cure rates. A new strategy combining maximal cytoreductive surgery(CRS) with intraoperative hyperthermic intraperitoneal chemotherapy(HIPEC) has been proposed to treat advanced stage EOC in the primary setting. Numerous small, heterogeneous studies have been conducted exploring outcomes in patients with predominantly advanced, recurrent or refractory disease treated with CRS + HIPEC. Although morbidity rates approaching 35% have been reported, oncologic outcomes are promising. Incorporation of HIPEC for the treatment of primary EOC has continued to gain interest. Several prospective phase 2 clinical trials were recently completed evaluating the impact of CRS + HIPEC in the primary setting. This article will briefl y discuss the benefi ts of optimal surgical cytoreduction and the theoretical basis of intraperitoneal chemotherapy in patients with advanced stage EOC, and will then review existing literature describing oncologic outcomes in EOC patients treated with HIPEC in the primary setting. 展开更多
关键词 Epithelial ovarian cancer Cytoreductive surgery Hyperthermic intraperitoneal chemotherapy Intraperitoneal chemotherapy SURVIVAL TOXICITY
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Preoperative colonic stents vs emergency surgery for acute left-sided malignant colonic obstruction: meta-analysis with systematic review of the literature
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作者 Belinda De Simone Fausto Catena +6 位作者 Federico Coccolini Salomone Di Saverio Massimo Sartelli Arianna Heyer Nicola De Angelis Gian Luigi De Angelis Luca Ansaloni 《World Journal of Meta-Analysis》 2017年第1期1-13,共13页
AIM To investigate by meta-analytic study and systematic review, advantages of colonic stent placement in comparison with emergency surgery.METHODS We conducted an extensive literature search by PubMed, Google Scholar... AIM To investigate by meta-analytic study and systematic review, advantages of colonic stent placement in comparison with emergency surgery.METHODS We conducted an extensive literature search by PubMed, Google Scholar, Embase and the Cochrane Libraries. We searched for all the papers in English published till February 2016, by applying combinations of the following terms: Obstructive colon cancer, colon cancer in emergency, colorectal stenting, emergency surgery for colorectal cancer, guidelines for obstructive colorectal cancer, stenting vs emergency surgery in the treatment of obstructive colorectal cancer, selfexpanding metallic stents, stenting as bridge to surgery. The study was designed following the PrismaStatement. By our search, we identified 452 studies, and 57 potentially relevant studies in full-text were reviewed by 2 investigators; ultimately, 9 randomized controlled trials were considered for meta-analysis and all the others were considered for systematic review.RESULTS In the meta-analysis, by comparing colonic stenting(CS) as bridge to surgery and emergency surgery, the pooled analysis showed no significant difference between the two techniques in terms of mortality [odds ratio(oR) = 0.91], morbidity(oR = 2.38) or permanent stoma rate(oR = 1.67); primary anastomosis was more frequent in the stent group(oR = 0.45; P = 0.004) and stoma creation was more frequent in the emergency surgery group(oR = 2.36; P = 0.002). No statistical difference was found in disease-free survival and overall survival. The pooled analysis showed a significant difference between the colonic stent and emergency surgery groups(oR = 0.37), with a significantly higher 1-year recurrence rate in the stent group(P = 0.007).CONCLUSION CS improves primary anastomosis rate with significantly high 1-year follow-up recurrence and no statistical difference in terms of disease-free survival and overall survival. 展开更多
关键词 COLONIC STENT Self-expandable metallic STENT OBSTRUCTIVE left colon cancer Emergency surgery Endo-laparoscopic approach Oncological outcome
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Advanced ovarian cancer: Neoadjuvant chemotherapy plus surgery and HIPEC as up-front treatment
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作者 Federico Coccolini Fausto Catena +3 位作者 Roberto Manfredi Marco Lotti Luigi Frigerio Luca Ansaloni 《World Journal of Obstetrics and Gynecology》 2012年第4期55-59,共5页
Epithelial ovarian cancer (EOC) is one of the most com-mon malignancies and one of the principal causes of death in gynecological neoplasms. The majority of EOC patients present with an advanced International Fed-er... Epithelial ovarian cancer (EOC) is one of the most com-mon malignancies and one of the principal causes of death in gynecological neoplasms. The majority of EOC patients present with an advanced International Fed-eration of Gynecology and Obstetrics stage disease. The current standard treatment for these patients con-sists of complete cytoreduction and combined systemic chemotherapy of a platinum agent and paclitaxel. Even if the majority of patients with EOC respond to frst-line platinum based chemotherapy, almost 20% of them are resistant or refractory. According to these data, the main risk is for a certain number of patients to have undergone cytoreductive surgery (CRS) and subsequent hyperthermic intraoperative peritoneal chemotherapy (HIPEC) in a useful way. Radical surgery, especially in advanced cases, is associated with a high incidence of postoperative morbidity and mortality, which could be increased by the HIPEC. Every effort should be made for previously selected patients to improve outcome and optimize resources. Over the last decade, new options have been introduced to prolong survival. Im-proved long-term results can be achieved using CRS in combination with intraoperative HIPEC. This combina-tion has also been used in an up-front setting. Contro-versial outcomes have been reported for neoadjuvant platinum-based chemotherapy. Different papers have been published reporting discordant results. Further studies are needed. 展开更多
关键词 Epithelian ovarian cancer Hyperthermic intraoperative peritoneal chemotherapy Up-front Neo-adjuvant TREATMENT Oncology Cytoreductive surgery CHEMOTHERAPY
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Use of indocyanine green fluorescence for triple gallbladder cholecystectomy: A case report
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作者 Caterina Froiio Laura Torselli +7 位作者 Luca Bottero Nirvana Maroni Dario Palmisano Pasquale Chiacchio Cristian Giuseppe Monaco Laura Palvarini Giovanni Pompili Andrea Pisani Ceretti 《Laparoscopic, Endoscopic and Robotic Surgery》 2024年第4期186-189,共4页
Triple gallbladder is a rare anatomical anomaly resulting from impaired embryological regression of the biliary tract during the 5th week of gestation.1 This entitywas first described by Huber during an autopsy in 175... Triple gallbladder is a rare anatomical anomaly resulting from impaired embryological regression of the biliary tract during the 5th week of gestation.1 This entitywas first described by Huber during an autopsy in 1752,2 and the first clinical case was published by Boni et al in 1958.3 Since then,only 22 cases have been reported in the literature.4,5 The low incidence of this biliary tract anomaly and the nonspecific clinical presentation,usually biliary colic or cholecystitis,make a challenging clinical diagnosis.Multimodal imaging examination is required for confirmed diagnosis. 展开更多
关键词 GALLBLADDER IMPAIRED CLINICAL
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Adhesive small bowel adhesions obstruction: Evolutions in diagnosis, management and prevention 被引量:30
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作者 Fausto Catena Salomone Di Saverio +4 位作者 Federico Coccolini Luca Ansaloni Belinda De Simone Massimo Sartelli Harry Van Goor 《World Journal of Gastrointestinal Surgery》 SCIE CAS 2016年第3期222-231,共10页
Intra-abdominal adhesions following abdominal surgery represent a major unsolved problem. They are the first cause of small bowel obstruction. Diagnosis is based on clinical evaluation, water-soluble contrast followth... Intra-abdominal adhesions following abdominal surgery represent a major unsolved problem. They are the first cause of small bowel obstruction. Diagnosis is based on clinical evaluation, water-soluble contrast followthrough and computed tomography scan. For patients presenting no signs of strangulation, peritonitis or severe intestinal impairment there is good evidence to support non-operative management. Open surgery is the preferred method for the surgical treatment of adhesive small bowel obstruction, in case of suspected strangulation or after failed conservative management, but laparoscopy is gaining widespread acceptance especially in selected group of patients. "Good" surgical technique and anti-adhesive barriers are the main current concepts of adhesion prevention. We discuss current knowledge in modern diagnosis and evolving strategies for management and prevention that are leading to stratified care for patients. 展开更多
关键词 ADHESIVE DISEASE Intestinal OBSTRUCTION DIAGNOSIS of ADHESIVE small bowel OBSTRUCTION NONOPERATIVE MANAGEMENT of ADHESIVE DISEASE Emergency surgical treatment
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Advanced gastric cancer:what we know and what we stillhave to learn 被引量:27
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作者 Federico Coccolini Giulia Montori +6 位作者 Marco Ceresoli Simona Cima Maria Carla Valli Gabriela E Nita Arianna Heyer Fausto Catena Luca Ansaloni 《World Journal of Gastroenterology》 SCIE CAS 2016年第3期1139-1159,共21页
Gastric cancer is a common neoplastic disease and, more precisely, is the third leading cause of cancer death in the world, with differences amongst geographic areas. The definition of advanced gastric cancer is still... Gastric cancer is a common neoplastic disease and, more precisely, is the third leading cause of cancer death in the world, with differences amongst geographic areas. The definition of advanced gastric cancer is still debated. Different stadiating systems lead to slightly different stadiation of the disease, thus leading to variations between the single countries in the treatment and outcomes. In the present review all the possibilities of treatment for advanced gastric cancer have been analyzed. Surgery, the cornerstone of treatment for advanced gastric cancer, is analyzed first, followed by an investigation of the different forms and drugs of chemotherapy and radiotherapy. New frontiers in treatment suggest the growing consideration for intraperitoneal administration of chemotherapeutics and combination of traditional drugs with new ones. Moreover, the necessity to prevent the relapse of the disease leads to the consideration of administering intraperitoneal chemotherapy earlier in the therapeutical algorithm. 展开更多
关键词 Advanced gastric cancer Chemotherapy Hypertermic intraperitoneal chemotherapy INTRAPERITONEAL Surgery Definition
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Subcapsular hepatic haematoma of the right lobe following endoscopic retrograde cholangiopancreatography: Case report and literature review 被引量:6
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作者 Marco Antonio Zappa Alberto Aiolfi +2 位作者 Ilaria Antonini Cinzia Domenica Musolino Andrea Porta 《World Journal of Gastroenterology》 SCIE CAS 2016年第17期4411-4415,共5页
Sub capsular hepatic haematoma is a rare complication after endoscopic retrograde cholangiopancreatography (ERCP). Exact pathological mechanism is still unclear and few reports are nowadays available in literature. We... Sub capsular hepatic haematoma is a rare complication after endoscopic retrograde cholangiopancreatography (ERCP). Exact pathological mechanism is still unclear and few reports are nowadays available in literature. We report the case of a 58-year-old woman with recurrent episodes of upper abdominal pain, nausea and vomiting. On the basis of laboratory exams, abdomen ultrasound and magnetic resonance imaging she was diagnosed with a common bile duct stone. Endoscopic biliary sphincterotomy was performed. On the following day the patient complaint severe abdominal pain with rebound and hemodynamic instability. A computed tomography scan reveal a 14 cm &#x000d7; 6 cm &#x000d7; 19 cm sub-capsular hepatic haematoma on the right lobe that was successfully managed via percutaneous embolization. Sub capsular liver haematoma is a rare life threatening complication after ERCP that should be managed according to patients&#x02019; haemodynamic and clinic. 展开更多
关键词 Endoscopic guidewire Endoscopic retrograde cholangiopancreatography Abdominal pain Subcapsular hepatic hematoma EMBOLIZATION
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Gastrointestinal stromal tumor and mitosis,pay attention 被引量:2
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作者 Federico Coccolini Fausto Catena +1 位作者 Luca Ansaloni Antonio Daniele Pinna 《World Journal of Gastroenterology》 SCIE CAS CSCD 2012年第6期587-588,共2页
The difference between stages I and ]]I of gastric gas- trointestinal stromal tumor depends principally on the number of mitosis. According with TNM classification, the presence in the tumor of high mitotic rate deter... The difference between stages I and ]]I of gastric gas- trointestinal stromal tumor depends principally on the number of mitosis. According with TNM classification, the presence in the tumor of high mitotic rate deter- mines the upgrading. Many studies exposed different count techniques in evaluating the number of mitosis. An international standardized method to assess mitotic rate is needed. 展开更多
关键词 Gastrointestinal stromal tumor MITOSIS Clas-sification GASTROESOPHAGEAL Enudeation
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Cytoreductive surgery in primary advanced epithelial ovarian cancer 被引量:1
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作者 Luca Ansaloni Federico Coccolini +2 位作者 Fausto Catena Luigi Frigerio Robert E Bristow 《World Journal of Obstetrics and Gynecology》 2013年第4期116-123,共8页
Epithelial ovarian cancer is one of the most common malignancy and one of the principal causes of death among gynaecological neoplasm. The majority of patients(about 70%) present with an advanced International Federat... Epithelial ovarian cancer is one of the most common malignancy and one of the principal causes of death among gynaecological neoplasm. The majority of patients(about 70%) present with an advanced International Federation of Gynaecology and Obstetrics stage disease. The current standard treatment for these patients consists of complete cytoreduction and combined systemic chemotherapy(CT). An increasing proportion of patients undergoing complete cytoreduction to no gross residual disease(RD) is associated with progressively longer overall survival. As a counterpart, some authors hypothesized the improving in survival could be due more to a less diffused initial disease than to an increase in surgical cytoreduction rate. Moreover the biology of the tumor plays an important role in survival benefi t of surgery. It's still undefi ned how the intrinsic features of the tumor make intra-abdominal implants easier to remove.Adjuvant and hyperthermic intraperitoneal CT could play a decisive role in the coming years as the completeness of macroscopic disease removal increases with advances in surgical techniques and technology. The introduction of neo-adjuvant CT moreover will play a decisive role in the next years Anyway cytoreduction with no macroscopic residual of disease should always be attempted. However the defi nition of RD is not universal. A unique and defi nitive defi nition is needed. 展开更多
关键词 Ovarian cancer CYTOREDUCTION COMPLETE Hyperthermic intraperitoneal chemotherapy
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NOTES-Natural orifice transluminal endoscopic surgery:Why not?
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作者 Antonello Forgione 《World Journal of Gastrointestinal Surgery》 SCIE CAS 2010年第6期177-178,共2页
Since natural orifice transluminal endoscopic surgery(NOTES) was first described by Anthony Kalloo,it has attracted tremendous interest from surgeons and gastroenterologist all around the world.This special issue of t... Since natural orifice transluminal endoscopic surgery(NOTES) was first described by Anthony Kalloo,it has attracted tremendous interest from surgeons and gastroenterologist all around the world.This special issue of the World Journal of Gastrointestinal Surgery explores the current possibilities and future potential of the most disruptive revolution in the field of surgery represented by the NOTES approach.In the future,new technologies developed for this approach and deeper insight into several gastrointestinal diseases will lead to the design of completely new interven tional procedures and change the way we will operate,bringing us to the previously unimaginable goal of "no scar surgery". 展开更多
关键词 GASTROINTESTINAL SURGERY MINIMALLY invasive SURGERY Natural ORIFICE TRANSLUMINAL endoscopic SURGERY MICROROBOTICS
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Use of short stems in revision of standard femoral stem:A case report
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作者 Francesco Roberto Evola Giuseppe Evola Giuseppe Sessa 《World Journal of Orthopedics》 2020年第11期528-533,共6页
BACKGROUND Short stems are usually uncemented prosthetics and are recommended in the treatment of traumatic or degenerative diseases of hip.In revision procedures for elderly patients with serious comorbidity,applying... BACKGROUND Short stems are usually uncemented prosthetics and are recommended in the treatment of traumatic or degenerative diseases of hip.In revision procedures for elderly patients with serious comorbidity,applying a short stem could reduce peri-and post-operative secondary surgical risks to femoral osteotomy,which are necessary for the removal of parts of the implant or acrylic cement from the medullary canal.There are no cases in the literature that apply a short stem for prosthetic revision by acrylic cement anchorage.CASE SUMMARY A male patient had a left hip replacement in 1995 due to coxarthrosis.At the age of eighty the patient reported an accidental trauma and walked with pain in the left thigh.The X-ray highlighted the stem breakage in the distal section without fracturing the femoral cortex.The patient had various comorbidities(diabetes,anaemia,heart deficiency,and arrhythmia)presenting a high operation risk(ASA 4).During the revision procedure,the distal apex of the stem could not be removed from the femoral cortex.Because of the poor general health of the patient,the surgeon decided not to perform a Wagner femoral osteotomy to remove the distal section of the stem and decided to implant a short stem to avoid removing the stem section of the previous implant.The patient had his left femur X-rayed 15 d post-trauma.CONCLUSION A field of application of short stem may be the development of a cemented short stem to reduce the complexity of the revision procedure. 展开更多
关键词 Short stem Revision procedure Cementless implant Total hip replacement Prosthesis design Case report
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What paradigm shifts occurred in the management of acute diverticulitis during the COVID-19 pandemic?A scoping review
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作者 Gaetano Gallo Monica Ortenzi +5 位作者 Ugo Grossi Gian Luca Di Tanna Francesco Pata Mario Guerrieri Giuseppe Sammarco Salomone Di Saverio 《World Journal of Clinical Cases》 SCIE 2021年第23期6759-6767,共9页
BACKGROUND Acute colonic diverticulitis(ACD)is common in Western countries,with its prevalence increasing throughout the world.As a result of the coronavirus disease 2019(COVID-19),elective surgery and in-patients’vi... BACKGROUND Acute colonic diverticulitis(ACD)is common in Western countries,with its prevalence increasing throughout the world.As a result of the coronavirus disease 2019(COVID-19),elective surgery and in-patients’visits have been cancelled or postponed worldwide.AIM To systematically explore the impact of the pandemic in the management of ACD.METHODS MEDLINE,Embase,Scopus,MedxRiv,and the Cochrane Library databases were searched to 22 December 2020.Studies which reported on the management of patients with ACD during the COVID-19 pandemic were eligible.For cross sectional studies,outcomes of interest included the number of hospital admission for ACD,as well as key features of disease severity(complicated or not)across two time periods(pre-and during lockdown).RESULTS A total of 69 papers were inspected,and 21 were eligible for inclusion.Ten papers were cross sectional studies from seven world countries;six were case reports;three were qualitative studies,and two review articles.A 56%overall decrease in admissions for ACD was observed during lockdown,peaking 67%in the largest series.A 4%-8%decrease in the rate of uncomplicated diverticulitis was also noted during the lockdown phase.An initial non-operative management was recommended for complicated diverticulitis,and encouraged to an out-of-hospital regimen.Despite initial concerns on the use of laparoscopy for Hinchey 3 and 4 patients to avoid aerosolized contamination,societal bodies have progressively mitigated their initial recommendations as actual risks are yet to be ascertained.CONCLUSION During the COVID-19 pandemic,fewer patients presented and were diagnosed with ACD.Such decline may have likely affected the spectrum of uncomplicated disease.Established outpatient management and follow up for selected cases may unburden healthcare resources in time of crisis. 展开更多
关键词 COVID-19 SARS-CoV-2 Acute diverticulitis Diverticular disease Hartmann
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Acknowledgments to reviewers of World Journal of Obstetrics and Gynecology
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作者 Byron Asimakopoulos Chie-Pein Chen, MD +8 位作者 Emmanuel Bujold Erich Cosmi MD Fanuel Lampiao Federico Coccolini Ioannis E Messinis Marjan Khajehei Polat Dursun Shi-Yann Cheng Sorina Grisaru-Granovsky 《World Journal of Obstetrics and Gynecology》 2012年第1期3-3,共1页
Many reviewers have contributed their expertise and time to the peer review,a critical process to ensure the quality of World Journal of Obstetrics and Gynecology.The editors and authors of the articles submitted to t... Many reviewers have contributed their expertise and time to the peer review,a critical process to ensure the quality of World Journal of Obstetrics and Gynecology.The editors and authors of the articles submitted to the journal are grateful to the following reviewers for evaluating the articles(including those published in this issue and those rejected for this issue)during the last editing time period. 展开更多
关键词 《世界妇产科杂志》 期刊 编辑工作 发行工作
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经自然腔道内镜手术:临床应用与未来展望 被引量:2
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作者 Antonelo Forgione 施宏 朱江帆 《中国微创外科杂志》 CSCD 2009年第12期1060-1062,共3页
目的可弯曲内镜经自然腔道进入腹腔进行手术,标志着微创治疗在追求无瘢痕手术目标的重大进步。在众多研究机构数年的共同努力之下,自然腔道手术逐渐成为一种可靠的治疗方法,既能采用完全内镜方式,又可结合腹壁微创辅助支持。充满希望的... 目的可弯曲内镜经自然腔道进入腹腔进行手术,标志着微创治疗在追求无瘢痕手术目标的重大进步。在众多研究机构数年的共同努力之下,自然腔道手术逐渐成为一种可靠的治疗方法,既能采用完全内镜方式,又可结合腹壁微创辅助支持。充满希望的手术结果,及能左右患者决定并可引起极大关注的总是寻找疗效确切、微创、恢复迅速的治疗手段。上述因素不断推动相应专业的发展,而各种技术壁垒的突破将使自然腔道-无瘢痕手术更为简便,并能重复进行,甚至用于治疗复杂病例。自然腔道手术具有结束外科手术与瘢痕疼痛如影随形历史的潜能,并因高度重视患者身心健全,成为一种极具吸引力的手术选择。 展开更多
关键词 经自然腔道内镜手术 微创外科 微型机器人 先进技术
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Laparoscopic management of intra-abdominal infections:Systematic review of the literature 被引量:5
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作者 Federico Coccolini Cristian Tranà +7 位作者 Massimo Sartelli Fausto Catena Salomone Di Saverio Roberto Manfredi Giulia Montori Marco Ceresoli Chiara Falcone Luca Ansaloni 《World Journal of Gastrointestinal Surgery》 SCIE CAS 2015年第8期160-169,共10页
AIM: To investigate the role of laparoscopy in diagnosis and treatment of intra abdominal infections.METHODS: A systematic review of the literature was performed including studies where intra abdominal infections were... AIM: To investigate the role of laparoscopy in diagnosis and treatment of intra abdominal infections.METHODS: A systematic review of the literature was performed including studies where intra abdominal infections were treated laparoscopically.RESULTS: Early laparoscopic approaches have become the standard surgical technique for treating acute cholecystitis. The laparoscopic appendectomy has been demonstrated to be superior to open surgery in acute appendicitis. In the event of diverticulitis, laparoscopic resections have proven to be safe and effective procedures for experienced laparoscopic surgeons and may be performed without adversely affecting morbidity and mortality rates. However laparoscopic resection has not been accepted by the medical community as the primary treatment of choice. In high-risk patients, laparoscopic approach may be used for exploration or peritoneal lavage and drainage. The successful laparoscopic repair of perforated peptic ulcers for experienced surgeons, is demonstrated to be safe and effective. Regarding small bowel perforations, comparative studies contrasting open and laparoscopic surgeries have not yet been conducted. Successful laparoscopic resections addressing iatrogenic colonic perforation have been reported despite a lack of literature-based evidence supporting such procedures. In post-operative infections, laparoscopic approaches may be useful in preventing diagnostic delay and controllingthe source.CONCLUSION: Laparoscopy has a good diagnostic accuracy and enables to better identify the causative pathology; laparoscopy may be recommended for the treatment of many intra-abdominal infections. 展开更多
关键词 LAPAROSCOPY POST-OPERATIVE TREATMENT PERFORATION A
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Malignant transformation of ectopic pancreatic cells in the duodenal wall 被引量:3
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作者 Roberto Bini Paolo Voghera +4 位作者 Alberto Tapparo Raffaele Nunziata Andrea Demarchi Matteo Capocefalo Renzo Leli 《World Journal of Gastroenterology》 SCIE CAS CSCD 2010年第10期1293-1295,共3页
Ectopic pancreas (EP) is the relatively uncommon presence of pancreatic tissue outside the normal location of the pancreas. This condition is usually asymptomatic and rarely complicated by pancreatitis and malignant t... Ectopic pancreas (EP) is the relatively uncommon presence of pancreatic tissue outside the normal location of the pancreas. This condition is usually asymptomatic and rarely complicated by pancreatitis and malignant transformation. A few cases of neoplastic phenomena that developed from EP into the duodenal wall are described in the literature. Herein we report a case of gastric outlet obstruction due to adenocarcinoma arising from EP of the duodenal wall. The patient underwent a Whipple's procedure and had an uneventful post-operative recovery. Traditional imaging studies are often inconclusive in the definitive diagnosis, whilst endoscopic ultrasonography and guided biopsy may aid accurate pre-operative diagnosis. Diagnostic uncertainty warrants surgical exploration and if necessary extended resection is indicated. 展开更多
关键词 Ectopic pancreas DUODENUM Gastrointestinal obstruction NEOPLASM PANCREATICODUODENECTOMY
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Multimodal treatments of “gallstone cholangiopancreatitis” 被引量:1
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作者 Serafino Vanella Mario Baiamonte Francesco Crafa 《World Journal of Gastrointestinal Endoscopy》 2022年第7期467-470,共4页
Gallstone cholangiopancreatitis is a potentially life-threatening pathology which requires quick intervention involving endoscopists,interventional radiologists,anesthesiologists and surgeons in relation to clinical c... Gallstone cholangiopancreatitis is a potentially life-threatening pathology which requires quick intervention involving endoscopists,interventional radiologists,anesthesiologists and surgeons in relation to clinical conditions.Treatment possibilities are varied,especially with current progress in advanced endoscopy,interventional radiology,and minimally invasive surgery.The following treatments are available:endoscopic sphincterotomy(ES)with stone extraction followed by laparoscopic cholecystectomy;simultaneous endoscopic stone extraction with laparoscopic cholecystectomy(rendezvous technique);combined laparoscopic cholecystectomy and common bile duct(CBD)exploration;open CBD exploration;ES post-cholecystectomy;percutaneous placement of biliary drains for unstable patients,followed by percutaneous cholangioscopy;and lithotripsy with different approaches,including a laser and balloon dilation of the sphincter of Oddi.Each technique has its strengths and weaknesses,and there is great discussion in the literature on choosing the ideal approach based on the patient’s clinical conditions. 展开更多
关键词 Cholangiopancreatitis Common bile duct stones Endoscopic retrograde cholangiopancreatography Endoscopic sphincterotomy Laparoscopic common bile duct exploration PERCUTANEOUS
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Comprehensive management of epithelial ovarian cancer with peritoneal metastases 被引量:1
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作者 Luigi Frigerio Luca Ansaloni +2 位作者 Elia Poiasina Federico Coccolini Paul H Sugarbaker 《World Journal of Obstetrics and Gynecology》 2013年第4期108-115,共8页
Ovarian cancer has as its predominant pattern of dissemination metastases to the peritoneal surfaces and disease spread within the abdomen and pelvis that most commonly causes the patients demise. To combat peritoneal... Ovarian cancer has as its predominant pattern of dissemination metastases to the peritoneal surfaces and disease spread within the abdomen and pelvis that most commonly causes the patients demise. To combat peritoneal metastases, cytoreductive surgery with peritoneal and visceral resections is combined with intraperitoneal and systemic chemotherapy. Chemotherapy given in the operating room after the complete visible removal of ovarian cancer is hyperthermic intraperitoneal chemotherapy. The results of the combined treatment are determined by the extent of prior surgery, the extent of disease as established by the peritoneal cancer index, and the quality of the cytoreduction as measured by the completeness of cytoreduction score. Recent clinical information on patients with recurrent ovarian cancer suggest a median overall survival of up to 60 mo. These data are greatly improved over the one year survival observed in the past. 展开更多
关键词 Peritoneal metastases CARCINOMATOSIS Cytoreductive surgery Hyperthermic intraperitoneal chemotherapy Intraperitoneal chemotherapy CISPLATIN DOXORUBICIN IFOSFAMIDE Mitomycin C Intraperitoneal port
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