Roselle ( Hibiscus Sabdariffa L.) is a tropical and subtropical plant.This paper reviewed the distribution of roselle in China,and the varieties of roselle grown in China.The main chemical components of roselle calyce...Roselle ( Hibiscus Sabdariffa L.) is a tropical and subtropical plant.This paper reviewed the distribution of roselle in China,and the varieties of roselle grown in China.The main chemical components of roselle calyces were listed,and the nutritional health effects and the latest development and utilization of roselle calyx were summarized,in order to provide a reference for better promotion and cultivation of roselle.展开更多
Objective:To investigate the Knowledge-Attitude-Behavior(KAP)status and the influencing factors of protective behavior on COVID-19 among mobile phone users in Hainan province.Methods:From January 31 to February 8,2020...Objective:To investigate the Knowledge-Attitude-Behavior(KAP)status and the influencing factors of protective behavior on COVID-19 among mobile phone users in Hainan province.Methods:From January 31 to February 8,2020,questionnaires using the online"questionnaire star"platform were distributed to 901 mobile phone users in Hainan Province via WeChat,QQ and other social software channels,and 804 valid responses were collected.Results:The average score of knowledge was(61.22±22.453),and 71.5%of participants with good awareness of COVID-19;the average score of COVID-19 related attitude was(10.69±2.26),and 72.6%of participants with supportive attitudes;the average score of protective behaviors was(11.07±1.40),and 73.6%of participants with positive protective behaviors.Spearman correlation analysis showed a weak correlation between knowledge and attitude(r=0.183,P<0.001),a strong correlation between knowledge and behavior(r=0.770,P<0.05),and a weak correlation between behavior and attitude(r=0.23,P<0.001).Binary logistic analysis showed that knowledge(good vs.less:OR=1.515,95%CI:1.072-2.140;P<0.05)and attitude(supportive vs.non-supportive:OR=1.635,95%CI:1.154-2.316;P<0.05)were related to protective behavior of COVID-19.The major channels of acquiring COVID-19 related information were social software(80.0%),social platform(69.9%),TV(67.0%),and website(65.4%)respectively.Conclusions:During the high epidemic period of COVID-19,KAP status of Hainan mobile phone users were generally not good.Health education of COVID-19 should target the low educated groups by using new media.展开更多
Objective To understand the cognitive status and anxiety factors of COVID-19 in 804Hainan residents during the epidemic of corona virus disease 2019(COVID-19).Methods A cross-sectional survey was conducted on 804 Hain...Objective To understand the cognitive status and anxiety factors of COVID-19 in 804Hainan residents during the epidemic of corona virus disease 2019(COVID-19).Methods A cross-sectional survey was conducted on 804 Hainan residents.A non-randomized convenient sampling method combining with online and snowball recruitment method was used.Results The COVID-19 cognitive score of 804 Hainan residents was(61.22±22.45),with a total awareness rate of 71.5%;16.3%of the respondents had anxiety symptoms,and there were statistically significant differences among different populations of different genders,ages,educational backgrounds,and cognitive levels(P<0.05).The incidence of anxiety in women(18.1%),13-24years old(20.65%),low education(21.1%),and high cognition of SARS-CoV-2(19.4%)were higher than other groups.Binary Logistic regression analysis showed that the main influencing factors were gender,age and cognition status.Men were 0.563times higher than women(95%CI,0.348~0.911),the age group of 13-24 years old was 1.676times(95%CI,1.124-2.499)higher than 25-65 year old,and people with more COVID-19-related knowledge was 1.532 times higher than that with low cognition(95%CI,1.022~2.296).Conclusion The incidence of anxiety during the COVID-19epidemic was relatively high,and psychological counseling should be actively strengthened to relieve the anxiety symptoms.展开更多
Objective:To understand the role of ANP mRNA transcription regulation in gpl30-mediated cardiomyocyte hypertrophy,and the involved mitogen-aetivated protein kinase kinase(MEK)-extracellular signal-regulated kinase(ERK...Objective:To understand the role of ANP mRNA transcription regulation in gpl30-mediated cardiomyocyte hypertrophy,and the involved mitogen-aetivated protein kinase kinase(MEK)-extracellular signal-regulated kinase(ERK,also called p42/p44 MAPK)signaling pathway.Methods:isolated neonatal ventricular myocytes were treated with different concentrations of CT-1(10^(-9),10^(-8)and 10^(-7)mol/L).MTT was used to analyze the viability and RT-PCR was used to detect ANP mRNA levels in eardiomyocyte.To inhibit p42/p44 MAPK activity in hypertrophic cardiomyoeytes,the cells were pretreated with a specific MEKI inhibitor.Results:CT-1significantly induced ANP mRNA expression and the viability of canliomyocytes in a doseand time-dependent manner.Furthermore,blocking p42/p44 MAPK activity by the special MEk1 inhibitor uprcgulatcd the ANP mKNA.Conclusions:p42/p44 MAPK have an important role in suppressing ANP mRNA transcription and cell activity in gpl30-mediated hypertrophic ventricular myocytes.展开更多
Since December 2019, several cases of coronavirus infected disease 2019 (COVID-19) have been reported in Wuhan City, Hubei Province. COVID-19 has been rapid spread in other provinces of China and abroad. The preventio...Since December 2019, several cases of coronavirus infected disease 2019 (COVID-19) have been reported in Wuhan City, Hubei Province. COVID-19 has been rapid spread in other provinces of China and abroad. The prevention and control of outbreak is particularly important. Based on the development of network and medical and health resources in the context of the "Internet +" era, this article discusses strategies for the prevention and control of COVID-19 in the "Internet +" era, and provides a reference for the implementation of COVID-19 prevention and control.展开更多
基金Supported by 2016 Hainan Ecological Cycle Agricultural Project(QCN[2016]1347)Hainan Agricultural Youth Science and Technology Innovation Project(QCN[2017]1592)
文摘Roselle ( Hibiscus Sabdariffa L.) is a tropical and subtropical plant.This paper reviewed the distribution of roselle in China,and the varieties of roselle grown in China.The main chemical components of roselle calyces were listed,and the nutritional health effects and the latest development and utilization of roselle calyx were summarized,in order to provide a reference for better promotion and cultivation of roselle.
基金National natural science foundation of China(No.81860577)
文摘Objective:To investigate the Knowledge-Attitude-Behavior(KAP)status and the influencing factors of protective behavior on COVID-19 among mobile phone users in Hainan province.Methods:From January 31 to February 8,2020,questionnaires using the online"questionnaire star"platform were distributed to 901 mobile phone users in Hainan Province via WeChat,QQ and other social software channels,and 804 valid responses were collected.Results:The average score of knowledge was(61.22±22.453),and 71.5%of participants with good awareness of COVID-19;the average score of COVID-19 related attitude was(10.69±2.26),and 72.6%of participants with supportive attitudes;the average score of protective behaviors was(11.07±1.40),and 73.6%of participants with positive protective behaviors.Spearman correlation analysis showed a weak correlation between knowledge and attitude(r=0.183,P<0.001),a strong correlation between knowledge and behavior(r=0.770,P<0.05),and a weak correlation between behavior and attitude(r=0.23,P<0.001).Binary logistic analysis showed that knowledge(good vs.less:OR=1.515,95%CI:1.072-2.140;P<0.05)and attitude(supportive vs.non-supportive:OR=1.635,95%CI:1.154-2.316;P<0.05)were related to protective behavior of COVID-19.The major channels of acquiring COVID-19 related information were social software(80.0%),social platform(69.9%),TV(67.0%),and website(65.4%)respectively.Conclusions:During the high epidemic period of COVID-19,KAP status of Hainan mobile phone users were generally not good.Health education of COVID-19 should target the low educated groups by using new media.
基金National Natural Science Foundation of China(No.81860577)Chinese and western medicine for knee osteoarthritis.
文摘Objective To understand the cognitive status and anxiety factors of COVID-19 in 804Hainan residents during the epidemic of corona virus disease 2019(COVID-19).Methods A cross-sectional survey was conducted on 804 Hainan residents.A non-randomized convenient sampling method combining with online and snowball recruitment method was used.Results The COVID-19 cognitive score of 804 Hainan residents was(61.22±22.45),with a total awareness rate of 71.5%;16.3%of the respondents had anxiety symptoms,and there were statistically significant differences among different populations of different genders,ages,educational backgrounds,and cognitive levels(P<0.05).The incidence of anxiety in women(18.1%),13-24years old(20.65%),low education(21.1%),and high cognition of SARS-CoV-2(19.4%)were higher than other groups.Binary Logistic regression analysis showed that the main influencing factors were gender,age and cognition status.Men were 0.563times higher than women(95%CI,0.348~0.911),the age group of 13-24 years old was 1.676times(95%CI,1.124-2.499)higher than 25-65 year old,and people with more COVID-19-related knowledge was 1.532 times higher than that with low cognition(95%CI,1.022~2.296).Conclusion The incidence of anxiety during the COVID-19epidemic was relatively high,and psychological counseling should be actively strengthened to relieve the anxiety symptoms.
基金supported by a grant from the National Natural Science Foundation of China(30260032.81000073 and 81160020)Key Program of Science and Technology of Hainan Province(061011 and ZDXM20100045)+2 种基金Education Department of Hainan Province(Hj2007113)Natural Science Foundation of Hainan Province(310043 and 811197)Key Project of Chinese Ministry of Education(212137) and HJHZ2013-06
文摘Objective:To understand the role of ANP mRNA transcription regulation in gpl30-mediated cardiomyocyte hypertrophy,and the involved mitogen-aetivated protein kinase kinase(MEK)-extracellular signal-regulated kinase(ERK,also called p42/p44 MAPK)signaling pathway.Methods:isolated neonatal ventricular myocytes were treated with different concentrations of CT-1(10^(-9),10^(-8)and 10^(-7)mol/L).MTT was used to analyze the viability and RT-PCR was used to detect ANP mRNA levels in eardiomyocyte.To inhibit p42/p44 MAPK activity in hypertrophic cardiomyoeytes,the cells were pretreated with a specific MEKI inhibitor.Results:CT-1significantly induced ANP mRNA expression and the viability of canliomyocytes in a doseand time-dependent manner.Furthermore,blocking p42/p44 MAPK activity by the special MEk1 inhibitor uprcgulatcd the ANP mKNA.Conclusions:p42/p44 MAPK have an important role in suppressing ANP mRNA transcription and cell activity in gpl30-mediated hypertrophic ventricular myocytes.
文摘Since December 2019, several cases of coronavirus infected disease 2019 (COVID-19) have been reported in Wuhan City, Hubei Province. COVID-19 has been rapid spread in other provinces of China and abroad. The prevention and control of outbreak is particularly important. Based on the development of network and medical and health resources in the context of the "Internet +" era, this article discusses strategies for the prevention and control of COVID-19 in the "Internet +" era, and provides a reference for the implementation of COVID-19 prevention and control.
