Elevated brain temperature under severe heat exposure impairs cortical motor activity and executive function

Background:Excessive heat exposure can lead to hyperthermia in humans,which impairs physical performance and disrupts cognitive function.While heat is a known physiological stressor,it is unclear how severe heat stress affects brain physiology and function.Methods:Eleven healthy participants were subjected to heat stress from prolonged exercise or warm water immersion until their rectal temperatures(T_(re))attained 39.5℃,inducing exertional or passive hyperthermia,respectively.In a separate trial,blended ice was ingested before and during exercise as a cooling strategy.Data were compared to a control condition with seated rest(normothermic).Brain temperature(T_(br)),cerebral perfusion,and task-based brain activity were assessed using magnetic resonance imaging techniques.Results:T_(br)in motor cortex was found to be tightly regulated at rest(37.3℃±0.4℃(mean±SD))despite fluctuations in T_(re).With the development of hyperthermia,T_(br)increases and dovetails with the rising T_(re).Bilateral motor cortical activity was suppressed during high-intensity plantarflexion tasks,implying a reduced central motor drive in hyperthermic participants(T_(re)=38.5℃±0.1℃).Global gray matter perfusion and regional perfusion in sensorimotor cortex were reduced with passive hyperthermia.Executive function was poorer under a passive hyperthermic state,and this could relate to compromised visual processing as indicated by the reduced activation of left lateral-occipital cortex.Conversely,ingestion of blended ice before and during exercise alleviated the rise in both T_(re)and T_(bc)and mitigated heat-related neural perturbations.Conclusion:Severe heat exposure elevates T_(br),disrupts motor cortical activity and executive function,and this can lead to impairment of physical and cognitive performance.

Research on Energy-Saving Performance of Intermittent Heating for Rooms in Hot Summer&ColdWinter Zone

In the hot summer&cold winter zone in China,intermittent heating space for rooms is widely used.However,in comparison with continuous space heating,the energy-saving performance of intermittent space heating has not been sufficiently investigated.This paper studied the factors influencing the energy performance of intermittent heating for the representativeoffice inhot summer&coldwinter zone.Basedon theheatbalancemethod,adynamic thermalmodel of the intermittent heating roomwas built and tested by experiments.And then,it analyzed the total space heating load,the amount of energy saving and energy saving ratio of the intermittent heating under different preheating hours,occupation hours,required roomtemperatures,air change rates,overall heat transfer coefficients(U-value)of windows and wall materials.If the adjacent rooms were not heated,for a typical room occupied about 10 h a day,the energy-saving ratio of intermittent heating was about 30%compared with continuous heating.But the preheating power was higher than two times of continuous heating.The results also indicated that the occupation hours had a significant effect on energy saving amount and ratio,it should be noted that the energy saving ratio by intermittent heating was much lower than the unoccupied period ratio.Relative to other factors,the heating temperatures,room air change rates and U-value of windows,and room envelope materials had little effect on energy efficiency.If the adjacent rooms were heated in the same manner as the roomin question,the energy-saving ratio of the total load of intermittent heating was heavily reduced to 8.46%.

Channel Flows in Plate Heat Exchangers with the Aid of Particle Tracking Velocimetry

Channel flows of Plate Heat Exchangers (PHEs) were assessed by experiments with three different chevron angle arrangements in turbulent regime. Two chevron angles were selected to assess low and high pressure drop channels, besides a third mixed configuration as to achieve in-between results regarding hydraulic performance. Friction factor correlations were provided with the channel Reynolds number ranging from 1175 to 8325. Two-dimensional (2D) mean velocity field was obtained by Particle Tracking Velocimetry (PTV) with Reynolds number equal to 3450. To the best of our knowledge, this is the first experimental study that quantified the complete 2D velocity field of a typical PHE channel. This value allowed comparison with literature results of Plate and Shell Heat Exchanger (PSHE) channels with the same Reynolds number. PSHE mean velocity field is highly heterogeneous as compared to the one obtained for PHE channels. Peak velocity magnitude in the PSHE center is 50% higher than its bulk velocity, whereas this value is only 15% higher in the PHE center. Pressure drop in PHE mixed channels cannot be approximated by averaging chevron angles: furrow flow prevailed in the specified conditions. The axial velocity is asymmetric regarding the vertical plane. Smooth streamlines prevail in the channel inlet. Recirculation zones at the channel exit affect pipe flow in the manifold outlet with swirling flow structures. The necessary length to obtain fully developed pipe flow at the channel outlet was estimated. Significant velocity components occur in the distribution areas and can limit the heat exchanger performance. The results reported herein are essential to understand how the PHE channel geometry affects the velocity field and, therefore, local heat transfer and dissipation processes.

Modeling and Optimization of Solar Collector Design for the Improvement of Solar-Air Source Heat Pump Building Heating System

To enhance system stability,solar collectors have been integrated with air-source heat pumps.This integration facilitates the concurrent utilization of solar and air as energy sources for the system,leading to an improvement in the system’s heat generation coefficient,overall efficiency,and stability.In this study,we focus on a residential building located in Lhasa as the target for heating purposes.Initially,we simulate and analyze a solar-air source heat pump combined heating system.Subsequently,while ensuring the system meets user requirements,we examine the influence of solar collector installation angles and collector area on the performance of the solar-air source heat pump dual heating system.Through this analysis,we determine the optimal installation angle and collector area to optimize system performance.

Research on Operation Optimization of Heating System Based on Electric Storage Coupled Solar Energy and Air Source Heat Pump

For heating systems based on electricity storage coupled with solar energy and an air source heat pump(ECSA),choosing the appropriate combination of heat sources according to local conditions is the key to improving economic efficiency.In this paper,four cities in three climatic regions in China were selected,namely Nanjing in the hot summer and cold winter region,Tianjin in the cold region,Shenyang and Harbin in the severe cold winter region.The levelized cost of heat(LCOH)was used as the economic evaluation index,and the energy consumption and emissions of different pollutants were analyzed.TRNSYS software was used to simulate and analyze the system performance.The Hooke-Jeeves optimization algorithm and GenOpt software were used to optimize the system parameters.The results showed that ECSA systemhad an excellent operation effect in cold region and hot summer and cold winter region.Compared with ECS system,the systemenergy consumption,and the emission of different pollutants of ECSA system can be reduced by a maximum of 1.37 times.In cold region,the initial investment in an air source heat pump is higher due to the lower ambient temperature,resulting in an increase in the LOCH value of ECSA system.After the LOCH value of ECSA system in each region was optimized,the heating cost of the system was reduced,but also resulted in an increase in energy consumption and the emission of different pollutant gases.

Simulation Analysis of Flue Gas Waste Heat Utilization Retrofit Based on ORC System

Recovery of waste heat from boiler flue gas is an effective way to improve energy utilization efficiency.Taking a heating station heating project as an example,the existing heating system of this heating station was analyzed for its underutilized flue gas waste heat and low energy utilization rate.Rankine cycle is an effective waste heat recovery method,and a steam boiler organic Rankine cycle(ORC)cogeneration waste heat utilization method is proposed.The system model simulation is constructed and verified.First,a thermodynamic model was constructed in MATLAB and five suitable work gases were selected to analyze the effects of evaporation temperature and condensation temperature on the network and thermal efficiency of the waste heat cycle power system.Secondly,the ORC model is invoked in TRNSYS to construct the improved cogeneration system,and the rationality of the remaining heat utilization methods is determined by calculating and analyzing the thermal performance,economy,and environmental protection of the improved system.The simulation results show that the system can generate about 552,000 kWh of electricity per year,and improving the energy utilization rate from 0.72 to 0.78.

Modulation of Steady-State Heat Transport in a Dissipative Multi-Mode Qubit-Photon System

Quantum heat transport is considered as an indispensable branch of quantum thermodynamics to potentially improve performance of thermodynamic devices.We theoretically propose a dissipative qubit-photon system composed of multiple coupled resonators interacting with a single two-level qubit,to explore the steady-state heat transport by tuning both the inter-resonator photon hopping and the qubit-photon coupling.Specifically in the three-mode case,the dramatic enhancement and suppression of the heat current into the central resonator can be modulated by the corresponding frequency,compared to the currents into two edge resonators.Moreover,fruitful cycle current components are unraveled at weak qubit-photon coupling,which are crucial to exhibit the nonmonotonic feature with increase of the reservoir temperature bias.In the one-dimensional case under the mean-field framework,the influence of the photon hopping on heat transport is analyzed.The steady-state heat current is comparatively enhanced to the single-mode limit at weak qubit-photon coupling,stemming from the nonvanishing mean-field photon excitation parameter and the additional cycle current component.We hope these obtained results may have possible applications in quantum thermodynamic manipulation and energy harvesting.

Experiment investigation on visualization and operating characteristics of closed loop plate oscillating heat pipe with parallel channels

Using ethanol or acetone as the working fluid, visualization of oscillations in steady state was observed visually by high-speed cameras, and temperature oscillating and heat transfer characteristics of closed-loop plate oscillating heat pipe with parallel channels(POHP-PC) were experimentally investigated by varying liquid filled ratios(50%, 70%, 85%), section scales(1 mm×1 mm and 1 mm×1.5 mm), inclination angles, working fluids and heating inputs. It was found that during operating there was mixed flow consisting of plug flow and annular flow in channels of oscillating heat pipe at steady-state. There was an equilibrium position for working fluid of condenser during oscillating, and periodic oscillations occurred up and down in the vicinity of equilibrium position. With heat input increasing, equilibrium position rose slowly as a result of vapor pressure of evaporation.Evaporation temperature oscillating amplitude possessed a trend of small-large-small and frequency trend was of small-large during steady-state. It may be generally concluded that temperature, whether evaporator or condenser, fluctuated sharply or rose continuously when oscillating heat pipe coming to dry burning state. Simultaneously, it was found that temperature difference of cooling water possibly dropped with heat input rising during dry burning state. Thermal resistance of No. 2 with acetone was lower than that of No. 1 during experiments, but No. 2 achieving heat transfer limit was earlier than No. 1. However, with ethanol, thermal resistance of No. 1 and No. 2 were similar with the heating input less than 110-120 W and filling ratios of 50% and 70%. And with filling ratio of 85%, heating transfer performance of No. 2 was better compared to No. 1 during all the experiments.

Pathological changes in the lung and brain of mice during heat stress and cooling treatment

BACKGROUND： Heatstroke often leads to multiple organ dysfunction syndrome （MODS） with a death rate of 40% or a neurological morbidity of 30%. These high rates in patients with heatstroke are largely due to the progression of heat stress to MODS, resulting in no specifi c treatment available. This study aimed to develop a mouse model of heat stress and determine the pathological changes in the lung and brain during heat stress and cooling treatment.METHODS： A mouse model of heat stress was established in a pre-warmed incubator set at 35.5 ± 0.5°C and with a relative humidity of 60% ± 5%. Rectal temperature was monitored, and at a temperature of 39 °C, 40 °C, 41 °C, or 42 °C, the mice were sacrifi ced. The remaining animals were removed from the incubator and cooled at an ambient temperature of 25 ± 0.5 °C and a humidity of 35% ± 5% for 12 or 24 hours at a temperature of 41 °C or for 6 hours at a temperature of 42 °C. The control mice were sham-heated at a temperature of 25 ± 0.5 °C and a humidity of 35% ± 5%. The lungs and brains of all animals were isolated. Hematoxylin and eosin staining and light microscopy were performed to detect pathological changes.RESULTS： All mice demonstrated a uniform response to heat stress. A low degree of heat stress induced marked pathological changes of the lungs. With the rise of the temperature to 42°C, progressively greater damage to the lungs with further congestion of the lung matrix, asystematic hemorrhage of alveolar space, abscission of alveolar epithelial cells, and disappearance of pulmonary alveolus tissue structure were detected. However, absorption of congestion and hemorrhage as well as recovery of pulmonary alveolus tissue structure was observed following cooling treatment at an ambient temperature. With a low degree of heat stress, the brain only showed moderate edema. Neuronal denaturation and necrosis were detected at a temperature of 42°C. Interestingly, the lesions in the brain were further aggravated at 42 °C regardless of cooling treatment, but recovery was observed after cooling treatment at 41 °C.CONCLUSIONS： The pathological changes of the lungs and brain of mice showed distinctive lesions following heat stress and cooling treatment, and they were correlated with the time and duration of cooling treatment. The results of this study are helpful for further study of the mechanisms linking heatstroke.

Effects of Heat Treatment on Properties of Polyester Filaments

Many properties of polyester filaments such as heat shrinkage, tenacity, elongation at break and etc. are greatly influenced by drawing, so post-drawing is important in downstream processing. As more and more profile fibers and multi-variance fibers used in textile industry, the properties of above two kinds of differential polyester filaments after drawing in different heat conditions were studied. Finally following conclusions were obtained: Firstly, the tenacity and elongation at break decreases with the rise of Tp. Secondly, the tenacity rises but the elongation at break decreases with the increase of Tb. Then, when the Tb is low, both the shrinkage in boiling water and hi hot air decreases with the rise of Tp, while, when the Tb is high, both the shrinkage rises with the rise of Tp. The last, both the shrinkage decreases with the rise of Tb.

The Impact of Soil Moisture Availability upon the Partition of Net Radiation into Sensible and Latent Heat Fluxes

The impact of soil moisture availability on the Bowen ratio and on the partition of net radiation flux into sensible, latent and soil heat fluxes was investigated by using one-dimensional primitive equations with a refined soil parameterization scheme. Simulation results presented that as soil moisture availability increases, the Bowen ratio and the partition of net radiation flux into sensible and soil heat fluxes decrease. The partition of net radiation flux into latent heat flux, however, increases. Quantitative relationships between Bowen ratio and the partitions with soil moisture availability were also given in this study.

Compound Heat Transfer Enhancement of a Converging-Diverging Tube with Evenly Spaced Twisted-tapes

Pressure drop and compound heat transfer characteristics of a converging-diverging tube with evenly spaced twisted-tapes （CD-T tube） have been investigated experimentally. Swirl was generated by evenly spaced twisted-tape elements which vary in twist ratio and rotation angle. Space ratio also has an important effect on the characteristics. For comparison, experiments in a smooth circular tube and a converging-diverging （CD） tube with-out twisted-tapes were carried out. The results show that the twisted-tape with twist ratio y=4.72 and rotation angle θ=180° has the best performance among the four types of twisted-tapes presented in this paper. At Reynolds number ranging from 3400 to 20000, when space ratio s=48.6, the heat transfer efficiency index, which increases as the Reynolds number increases, is 0.85-1.21 and 1.07-1.15 compared to that of a smooth circular tube and a CD tube without twisted-tape inserts, respectively.

Operating performance of novel reverse-cycle defrosting method based on thermal energy storage for air source heat pump

To solve the fundamental problem of insufficient heat available during defrosting while ensuring the efficient and safe system operation for air-source heat pumps (ASHPs). A novel reverse-cycle defrosting (NRCD) method based on thermal energy storage to eliminate frost off the outdoor coil surface was developed. Comparative experiments using both the stand reverse cycle defrosting (SRCD) method and the NRCD method were carried out on an experimental ASHP unit with a nominal 2.5 kW heating capacity. The results indicate that during defrosting operation, using the NRCD method improves discharge and suction pressures by 0.24 MPa and 0.19 MPa, respectively, shortens defrosting duration by 60%, and reduces the defrosting energy consumption by 48.1% in the experimental environment, compared with those by the use of SRCD method. Therefore, using the NRCD method can shorten the defrosting duration, improve the indoor thermal comfort, and reduce the defrosting energy consumption in defrosting.

Experimental and CFD Heat Transfer Studies of Al2Oa-Water Nanofluid in a Coiled Agitated Vessel Equipped with Propeller

This paper presents the heat transfer characteristics of A1203-water nanofluid in a coiled agitated vessel with propeller agitator. The experimental study was conducted using 0.10%, 0.20% and 0.30% volume concentra tion of A1203-water nanofluids. The results showed considerable enhancement of convective heat transfer using the nanofluids. The empirical correlations developed for Nusselt number in terms of Reynolds number, Prandtl number, viscosity ratio and volume concentration fit with the experimental data within ±10%. The heat transfer characteris tics were also simulated using computational fluid dynamics using FLUENT software with the standard ke model and multiple reference frame were adopted. The computational fluid dynamics （CFD） predicted Nusselt number agrees well with the experimental value and the discrepancy is found to be less than ＋8%.

Estimating Heat Fluxes by Merging Profile Formulae and the Energy Budget with a Variational Technique

A variational technique (VT) is applied to estimate surface sensible and latent heat fluxes based on observations of air temperature, wind speed, and humidity, respectively, at three heights (1 m, 4 m, and 10 m), and the surface energy and radiation budgets by the surface energy and radiation system (SERBS). The method fully uses all information provided by the measurements of air temperature, wind, and humidity profiles, the surface energy budget, and the similarity profile formulae as well. Data collected at Feixi experiment station installed by the China Heavy Rain Experiment and Study (HeRES) Program are used to test the method. Results show that the proposed technique can overcome the well-known unstablility problem that occurs when the Bowen method becomes singular; in comparison with the profile method, it reduces both the sensitivities of latent heat fluxes to observational errors in humidity and those of sensible heat fluxes to observational errors in temperature, while the estimated heat fluxes approximately satisfy the surface energy budget. Therefore, the variational technique is more reliable and stable than the two conventional methods in estimating surface sensible and latent heat fluxes.

Experimental and Numerical Study on Heat Transfer Enhancement of a Rectangular Channel with Discontinuous Crossed Ribs and Grooves

Experimental and numerical investigations have been conducted to study turbulent flow of water and heat transfer characteristics in a rectangular channel with discontinuous crossed ribs and grooves.The tests investigated the overall heat transfer performance and friction factor in ribbed and ribbed-grooved channels with rib angle of 30°.The experimental results show that the overall thermo-hydraulic performance for ribbed-grooved channel is increased by 10%-13.6% when compared to ribbed channel.The investigation on the effects of different rib angles and rib pitches on heat transfer characteristics and friction factor in ribbed-grooved channel was carried out using Fluent with SST(shear-stress transport) k-ω turbulence model.The numerical results indicate that the case for rib angle of 45° shows the best overall thermo-hydraulic performance,about 18%-36% higher than the case for rib angle of 0°.In addition,the flow patterns and local heat transfer characteristics for ribbed and ribbed-grooved channels based on the numerical simulation were also analyzed to reveal the mechanism of heat transfer enhancement.

Experimental Study of Fouling on Heat Transfer Surface During Forced Convective Heat Transfer

An experimental study was conducted to investigate the fouling process of calcium carbonate on the heat transfer surface, during forced convective heat transfer. The dynamic monitoring apparatus of fouling resistance was set up for the present experiments. The fouling behavio（s were examined under different factors including fluid velocity, hardness,alkalinity, solution temperature, and wall temperature. Asymptotic fouling curves varying with time were obtained. The fouling rate and asymptotic fouling resistance increased and the induction periods were shortened with the fluid velocity decreasing, hardness andalkalinity increasing, and solution temperature and heat transfer surface temperature increasing. Thecomponents of fouling that formed on the heat transfer surface included crystallization fouling and particulate fouling. The thermal performance parameter of fouling,ρfhf, varied from 380 to 2600 kg·W·（m^4·K）^-1, increasing with growing velocity and decreasing solution temperature, hardness or alkalinity. Furthermore, the thermal conductivity of fouling, λf, varied from 1.7 to 2.2 W·（m·K）^-1 .

3D Numerical Study on Compound Heat Transfer Enhancement of Converging-diverging Tubes Equipped with Twin Twisted Tapes

The paper presents a 3D numerical simulation of turbulent heat transfer and flow characteristics in converging-diverging tubes （CDs） and converging-diverg）ng tubes.equi.pped with twin counter-swirling twisted tapes （CDTs）. The effects of Reynolds number （Re= 10000-20000）, pitch length （P= 11.25, 22.5 mm）, rib height （e = 0.5, 0.8, 1.1 ram）, pitch ratio （8= 1 ＂ 8, 5 ＂ 4, 8 ＂ 1）, gap distance between twin t）visted tapes （b = 0.5, 4.5, 8.5 mm） and tape number （n = 2, 3, 4, 5, 6） on Nusselt number （Nu）, Iriction tactor 0＇） and thermal enhancement factor （r/） are investigated under uniform heat flux conditions,using water as working fluid. In order to illustrate the heat transter and tlu^d tlow mechamsms, flow structures m ~StJs and ~SDIs are presented. The obtained results reveal that all geometric parameters have important effects on the thermal performance of CD and CDT, and both CD and CDT show better thermal performance than plain tube at the constant pumping power. It is also found that the increases in the Nusselt number and friction factor for CDT are, respectively, up to 6.3%-35.7% and 1.75-5.3 times of thecorresponding bare CD. All CDTs have good thermal perbrmance with greater than 1 which indicates that the compound heat transfer technique of CDT is commendable for the maximum enhanced heat transfer rate.

Experimental Study on Emission Control of Premixed Catalytic Combustion of Natural Gas Using Preheated Air

In this paper the premixed catalytic combustion emissions such as CO, unburned hydrocarbon (UHC), NOx and the temperature distribution in the catalytic monolith with ultra low concentration of Pd were studied. Three types of monoliths were used for experiments and the temperature of preheated air was respectively 50℃ , 100℃ and 200℃ . The results showed that preheated air made radial temperature in the catalytic monolith uniform which helped to avoid local hot spots so as to decrease NOx emission. The experiment also proved that the shorter monolith showed much better catalytic combustion performance than longer one and the temperature at the exit of the shorter monolith was relatively lower. On the contrary, the temperature was higher in the longer monolith and the lethal NOx emission was slightly increased.

Expert consensus on the diagnosis and treatment of heat stroke in China

Heat stroke(HS)is a fatal disease caused by thermal damage in the body,and it has a very high mortality rate.In 2015,the People’s Liberation Army Professional Committee of Critical Care Medicine published the first expert consensus on HS in China,Expert consensus on standardized diagnosis and treatment for heat stroke.With an increased understanding of HS and new issues that emerged during the HS treatment in China in recent years,the 2015 consensus no longer meet the requirements for HS prevention and treatment.It is necessary to update the consensus to include the latest research evidence and establish a new consensus that has broader coverage,is more practical and is more in line with China’s national conditions.This new expert consensus includes new concept of HS,recommendations for laboratory tests and auxiliary examinations,new understanding of diagnosis and differential diagnosis,On-site emergency treatment and In-hospital treatment,translocation of HS patients and prevention of HS.