Influence of high magnetic field on as-cast structure of Cu-25wt.%Ag alloys

To investigate the influence of high magnetic field (HMF) on the solidification microstructure of Cu-25wt.%Ag alloy, the Cu-25wt.%Ag alloy was prepared under HMF of 12 T, and for comparison, the alloy solidified without HMF was also fabricated. Macro and microstructures of the alloys were observed using the stereomicroscope, and scanning electron microscope, field emission scanning electron microscopy. The weight percentages of the pro-eutectic and eutectic, Cu phase and Ag phase in eutectic, and precipitates of Ag phase in pro-eutectic were analyzed by using of IPP software. Results show that the morphology of the column dendrites changes into cellular dendrites and the grains are refined under HMF of 12 T. Meanwhile, the thickness of the eutectic wall increases, but the sizes of Cu phase and Ag phase and the eutectic lamellar spacings are decreased. The Ag precipitates in the Cu matrix become coarser and sparser. The weight percentage variation of the phases in the microstructure and the Cu-Ag binary phase diagram reveals that the eutectic point moves to the left of the eutectic point in the equilibrium condition and the supersaturated solid solubility of Ag decreases under HMF.

Effects of gradient high-field static magnetic fields on diabetic mice

Although 9.4 T magnetic resonance imaging(MRI) has been tested in healthy volunteers,its safety in diabetic patients is unclear.Furthermore,the effects of high static magnetic fields(SMFs),especially gradient vs.uniform fields,have not been investigated in diabetics.Here,we investigated the consequences of exposure to 1.0-9.4 T high SMFs of different gradients(>10 T/m vs.0-10 T/m)on type 1 diabetic(T1D) and type 2 diabetic(T2D) mice.We found that 14 h of prolonged treatment of gradient(as high as 55.5 T/m) high SMFs(1.0-8.6 T) had negative effects on T1D and T2D mice,including spleen,hepatic,and renal tissue impairment and elevated glycosylated serum protein,blood glucose,inflammation,and anxiety,while 9.4 T quasi-uniform SMFs at 0-10 T/m did not induce the same effects.In regular T1D mice(blood glucose>16.7 mmol/L),the>10 T/m gradient high SMFs increased malondialdehyde(P<0.01) and decreased superoxide dismutase(P<0.05).However,in the severe T1D mice(blood glucose≥30.0 mmol/L),the>10 T/m gradient high SMFs significantly increased tissue damage and reduced survival rate.In vitro cellular studies showed that gradient high SMFs increased cellular reactive oxygen species and apoptosis and reduced MS-1 cell number and proliferation.Therefore,this study showed that prolonged exposure to high-field(1.0-8.6 T)>10 T/m gradient SMFs(35-1 380 times higher than that of current clinical MRI)can have negative effects on diabetic mice,especially mice with severe T1D,whereas 9.4 T high SMFs at 0-10T/m did not produce the same effects,providing important information for the future development and clinical application of SMFs,especially high-field MRI.

Effects of 3.7 T-24.5 T high magnetic fields on tumor-bearing mice

Since high magnetic field（MF） intensity can improve the image quality and reduce magnetic resonance imaging（MRI） acquisition time, the field intensity of MRIs has continued to increase over the past few decades. Although MRIs in most current hospitals are 0.5 T–3 T, there are preclinical studies have been carried out using 9.4 T MRI, and engineers are also putting efforts on building MRIs with even higher MFs. However, the accompanied safety issue of high-field MRIs is an emergent question to address before their clinical applications. In the meantime, the static magnetic field（SMF） has been shown to inhibit tumor growth in previous studies. Here, we investigated both the safety issue and the anti-tumor potentials of 3.7 T–24.5 T SMFs on GIST-T1 gastrointestinal stromal tumor-bearing nude mice. We followed up the mice three weeks after their exposure to high SMF and found that none of the mice died or had severe organ damage, except for slightly decreased food intake, weight gain, and liver function. Moreover, the tumor growth was inhibited by 3.7 T–24.5 T SMFs（up to ～54%）. It is interesting that the effects are more dependent on MF gradient than intensities, and for the same gradient and intensity, mice responded differently to hypogravity and hypergravity conditions. Therefore, our study not only demonstrated the safeness of high SMFs up to 24.5 T on mice but also revealed their anti-tumor potentials in the future.

Terahertz magnetic resonance in MnCr_(2)O_(4)under high magnetic field

Terahertz(THz)time-domain spectroscopy(THz-TDS)of polycrystalline MnCr_(2)O_(4)was performed at<9 T and low temperatures.A resonance absorption in the sub-THz range with linear blueshifts was observed as the magnetic field was increased from 4 T to 9 T.These magnetism-driven absorptions originated from a ferromagnetic resonance,which agrees with low-field electron spin resonance measurements and ferromagnetic resonance theory.The low-temperature g-factors of MnCr_(2)O_(4)were also obtained using THz-TDS.This work provides new insights into the spin dynamics of chromite spinel compounds in the THz region.

Solid-state NMR reveals that oxygen tri-clusters make glass highly crackresistant

In a recent paper,advanced solid-state nuclear magnetic resonance(SSNMR)technology was employed to reveal the underlying mechanism contributing to the high hardness and exceptional resistance to fragmentation observed in certain special glasses[1].This study utilized SSNMR to analyze the atomic-scale internal structure of glass,enabling the quantification of the fraction of three-coordinated oxygen([^((3))O]).The research findings demonstrate a quantitative relationship between[^((3))O]and the resistance of glass to crack initiation.

Crystal growth, magnetic and electrical transport properties of the kagome magnet RCr_(6)Ge_(6)(R= Gd–Tm)

Kagome magnets have attracted considerable research attention due to the interplay between topology,magnetism and electronic correlations.In this study we report single-crystal synthesis of a series of the kagome magnets.RCr_(6)Ge_(6)(R=Gd-Tm) that possess defect-free Cr kagome lattices and systematically study their magnetic and electrical transport properties.The transition from a canted ferrimagnetic to a paramagnetic state in GdCr_(6)Ge_(6),TbCr_(6)Ge_(6),DyCr_(6)Ge_(6),HoCr_(6)Ge_(6),ErCr_(6)Ge_(6) and TmCr_(6)Ge_(6) occurs at 11.3 K,10.8 K,4.3 K,2.5 K,3.3 K and below 2 K,respectively,due to R-R interactions within the compounds.Magnetization measurements reveal highly anisotropic magnetism with canted magnetic moments in these compounds.In electrical transport,both negative and positive magnetoresistances at different magnetic fields and temperatures have been observed due to the competition between different scattering mechanisms.This work enriches our understanding of the Cr-based kagome magnets and paves the way to search for possible topological responses in this family.

Acetaminophen overdose-induced acute liver injury can be alleviated by static magnetic field

Acetaminophen(APAP),the most frequently used mild analgesic and antipyretic drug worldwide,is implicated in causing 46%of all acute liver failures in the USA and between 40%and 70%in Europe.The predominant pharmacological intervention approved for mitigating such overdose is the antioxidant N-acetylcysteine(NAC);however,its efficacy is limited in cases of advanced liver injury or when administered at a late stage.In the current study,we discovered that treatment with a moderate intensity static magnetic field(SMF)notably reduced the mortality rate in mice subjected to high-dose APAP from 40%to 0%,proving effective at both the initial liver injury stage and the subsequent recovery stage.During the early phase of liver injury,SMF markedly reduced APAPinduced oxidative stress,free radicals,and liver damage,resulting in a reduction in multiple oxidative stress markers and an increase in the antioxidant glutathione(GSH).During the later stage of liver recovery,application of vertically downward SMF increased DNA synthesis and hepatocyte proliferation.Moreover,the combination of NAC and SMF significantly mitigated liver damage induced by high-dose APAP and increased liver recovery,even 24 h post overdose,when the effectiveness of NAC alone substantially declines.Overall,this study provides a noninvasive non-pharmaceutical tool that offers dual benefits in the injury and repair stages following APAP overdose.Of note,this tool can work as an alternative to or in combination with NAC to prevent or minimize liver damage induced by APAP,and potentially other toxic overdoses.

MicroMagnetic.jl:A Julia package for micromagnetic and atomistic simulations with GPU support

MicroMagnetic.jl is an open-source Julia package for micromagnetic and atomistic simulations.Using the features of the Julia programming language,MicroMagnetic.jl supports CPU and various GPU platforms,including NVIDIA,AMD,Intel,and Apple GPUs.Moreover,MicroMagnetic.jl supports Monte Carlo simulations for atomistic models and implements the nudged-elastic-band method for energy barrier computations.With built-in support for double and single precision modes and a design allowing easy extensibility to add new features,MicroMagnetic.jl provides a versatile toolset for researchers in micromagnetics and atomistic simulations.

Pressure-induced magnetic phase and structural transition in SmSb_(2)

Motivated by the recent discovery of unconventional superconductivity around a magnetic quantum critical point in pressurized CeSb_(2),here we present a high-pressure study of an isostructural antiferromagnetic(AFM) SmSb_(2) through electrical transport and synchrotron x-ray diffraction measurements.At P_(C)~2.5 GPa,we found a pressure-induced magnetic phase transition accompanied by a Cmca→P4/nmm structural phase transition.In the pristine AFM phase below P_(C),the AFM transition temperature of SmSb_(2) is insensitive to pressure;in the emergent magnetic phase above P_(C),however,the magnetic critical temperature increases rapidly with increasing pressure.In addition,at ambient pressure,the magnetoresistivity(MR) of SmSb_(2) increases suddenly upon cooling below the AFM transition temperature and presents linear nonsaturating behavior under high field at 2 K.With increasing pressure above P_(C),the MR behavior remains similar to that observed at ambient pressure,both in terms of temperature-and field-dependent MR.This leads us to argue an AFM-like state for SmSb_(2) above P_(C).Within the investigated pressure of up to 45.3 GPa and the temperature of down to 1.8 K,we found no signature of superconductivity in SmSb_(2).

Rotating magnetic field inhibits Aβ protein aggregation and alleviates cognitive impairment in Alzheimer’s disease mice

Amyloid beta(Aβ)monomers aggregate to form fibrils and amyloid plaques,which are critical mechanisms in the pathogenesis of Alzheimer’s disease(AD).Given the important role of Aβ1-42 aggregation in plaque formation,leading to brain lesions and cognitive impairment,numerous studies have aimed to reduce Aβaggregation and slow AD progression.The diphenylalanine(FF)sequence is critical for amyloid aggregation,and magnetic fields can affect peptide alignment due to the diamagnetic anisotropy of aromatic rings.In this study,we examined the effects of a moderate-intensity rotating magnetic field(RMF)on Aβaggregation and AD pathogenesis.Results indicated that the RMF directly inhibited Aβamyloid fibril formation and reduced Aβ-induced cytotoxicity in neural cells in vitro.Using the AD mouse model APP/PS1,RMF restored motor abilities to healthy control levels and significantly alleviated cognitive impairments,including exploration and spatial and non-spatial memory abilities.Tissue examinations demonstrated that RMF reduced amyloid plaque accumulation,attenuated microglial activation,and reduced oxidative stress in the APP/PS1 mouse brain.These findings suggest that RMF holds considerable potential as a non-invasive,high-penetration physical approach for AD treatment.

Low-energy spin dynamics in a Kitaev material Na_(3)Ni_(2)BiO_(6) investigated by nuclear magnetic resonance

We perform ^(23)Na nuclear magnetic resonance(NMR) and magnetization measurements on an S=1,quasi-2D honeycomb lattice antiferromagnet Na_(3)Ni_(2)BiO_(6).A large positive Curie-Weiss constant of 22.9 K is observed.The NMR spectra at low fields are consistent with a zigzag magnetic order,indicating a large easy-axis anisotropy.With the field applied along the c*axis,the NMR spectra confirm the existence of a 1/3-magnetization plateau phase between 5.1 T and 7.1 T.The transition from the zigzag order to the 1/3-magnetization plateau phase is also found to be a first-order type.A monotonic decrease of the spin gap is revealed in the 1/3-magnetization plateau phase,which reaches zero at a quantum critical field H_(C)≈8.35 T before entering the fully polarized phase.These data suggest the existence of exchange frustration in the system along with strong ferromagnetic interactions,hosting the possibility for Kitaev physics.Besides,well below the ordered phase,the 1/T_(1) at high fields shows either a level off or an enhancement upon cooling below 3 K,which suggests the existence of low-energy fluctuations.

Study on a Highly Stabilized Power Supply for Hybrid-Magnet Superconducting Outsert

The superconducting outsert of the 40 T hybrid-magnet in High Magnetic Field Laboratory （HMFL） of Chinese Academy of Sciences （CAS） requires a highly stabilized power supply. In this paper, two kinds of power supply design are briefly presented and both advantages and disadvantages are analyzed. In order to overcome the drawbacks of switching power supply, a series regulated active filter is adopted and a new design is proposed which ensures cooperative relationship between the feedback control loops of the switching converter and the series regulated active filter. Besides, unlike the traditional switching power supply, which can generate positive voltage only, this new design can also generate negative voltage which is needed in the quench protection for the superconducting magnet. In order to demonstrate the effectiveness of the methodology, a low-power prototype has been accomplished. The simulation and experiment results show that the power supply achieves high precision under the combined action of two feedback control loops. The peak-to-peak amplitude of the output ripple voltage of the prototype is 0.063%, while the peak-to-peak amplitude of the output ripple current is 120 ppm.

Lorentz transmission electron microscopy for magnetic skyrmions imaging

Magnetic skyrmions have interesting properties,including their small size,topological stability,and extremely low threshold current for current-driven motion.Therefore,they are regarded as promising candidates for next-generation magnetic memory devices.Lorentz transmission electron microscopy(TEM)has an ultrahigh magnetic domain resolution(~2 nm),it is thus an ideal method for direct real-space imaging of fine magnetic configurations of ultra-small skyrmions.In this paper,we describe the basic principles of Lorentz-TEM and off-axis electron holography and review recent experimental developments in magnetic skyrmion imaging using these two methods.

High-Performance Visible Light Photodetector Based on BiSeI Single Crystal

The continuing demand for new optoelectronic devices drives researchers to seek new materials suitable for photodetector applications.Recently,ternary compound semiconductors have entered researchers’field of vision,among which chalcohalides have attracted special interest because of their rich properties and unique crystal structure consisting of atom chains and inter-chain van der Waals gaps.We have synthesized high-quality BiSeI single crystals with[110]-plane orientation and fabricated a photodetector.The optoelectronic measurements show a pronounced photocurrent signal with outstanding technical parameters,namely high responsivity(3.2 A/W),specific detectivity(7×10^(10) Jones)and external quantum efficiency(622%)for λ=635 nm,V_(ds)=0.1 V and P_(opt)=0.23 mW/cm^(2).The high performance of BiSeI photodetector and its layer structure make it a promising candidate for low-dimensional optoelectronic applications.

Real-space observation of individual skyrmions in helimagnetic nanostripes

Controllable formation and manipulation of domain walls in one-dimensional（1D） nanostripes underpins a promising type of emergent spintronic device. Magnetic skyrmion is topologically stable whirlpool-like spin texture and is expected to replace familiar domain wall phenomena to build such devices, owing to its prominent features including small size,topological stability and the small critical current required to move it. It is thus essential to understand skyrmions＇ properties in such a nanostructured element. In this paper, we mainly give fundamental insight into this issue. Experimental achievements in the formation and stability of individual skyrmions in the nanostripe are outlined in detail.

Overview and progress of X-nuclei magnetic resonance imaging in biomedical studies

Proton nuclear(^(1)H)is the observed nucleus on which most magnetic resonance imaging(MRI)applications depend.Most traditional^(1)H MRI can provide structural and functional information about organisms,while various non-proton nuclei(X-nuclei)MRI can provide more metabolic information.However,due to the relatively poor signal-to-noise ratio(SNR)of X-nuclei MRI,their applications are quite rare compared to^(1)H.Benefit from the rapid developments of MRI hardware and software technologies,X-nuclei MRI has recently attracted increasing interests in biomedical research.This review firstly introduces some current methods to improve the SNR of X-nuclei MRI.Secondly,this review describes biomedical applications of X-nuclei MRI,especially focusing on the current use of X-nuclei(^(13)C,^(17)O,^(19)F,^(23)Na and^(31)P)MRI to study related diseases in different organs,including the brain,liver,kidney,heart and bone.Finally,perspectives studies on X-nuclei imaging and its potential applications are described in biomedical research.

Microwave awakening the n-π^(*) electronic transition in highly crystalline polymeric carbon nitride nanosheets for photocatalytic hydrogen generation

The n-π^(*) electronic transition in polymeric carbon nitride(PCN)can remarkably harvest visible light,which thus potentially promotes the photocatalytic hydrogen H2 generation.However,awaking the n-π^(*) lectronic transition has proven to be a grand challenge.Herein,we reported on the awakening of n-π^(*) electronic transition by microwave thermolysis of urea pellet,which yielded the PCN with absorption edge of 600 nm,near 140 nm red-shift from 460 nm of pristine PCN.The n-π^(*) electronic transition endows PCN with an increased photocata lytic H_(2) generation,with a highest H_(2) rate of 61.7μmol h^(-1) under visible light exposure,which is near 6 times higher than that by using the PCN from the thermolysis of urea pellets in an electric furnace(10.6μmol h^(-1)).Furthermore,the n-π^(*) transition in PCN leads to the longest wavelength of 535 nm that can initiate H2 generation,remarkably longer than the absorption edge of pristine PCN(460 nm).This work manifests the advantages of microwave sintering route to awaken the n-π^(*) electronic transition in PCN for an increased photocata lytic performance.

Pressure Tuning of Magnetism and Drastic Increment of Thermal Conductivity under Applied Magnetic Field in HgCr_2S_4

HgCr2S4 is a typical compound manifesting competing ferromagnetic （FM） and antiferromagnetic （AFM） exchanges as well as strong spin-lattice coupling. Here we study these effects by intentionally choosing a combination of magnetization under external hydrostatic pressure and thermal conductivity at various magnetic fields. Upon applying pressure up to 10 kbar at 1 kOe, while the magnitude of magnetization reduces progressively, the AFM ordering temperature TN enhances concomitantly at a rate of about 1.5 K/kbar. Strikingly, at lO kOe the field polarized FM state is found to be driven readily back to an AFM one even at only 5kbar. In addition, the thermal conductivity exhibits drastic increments at various fields in the temperature range with strong spin fluctuations, reaching about 30% at 50 kOe. Consequently, the results give new experimental evidence of spin-lattice coupling. Apart from the colossal magnetoeapacitance and colossal magnetoresistance reported previously, the findings here may enable new promising functionalities for potential applications.

Electromagnetic Calculation and Plasma Leakage Rate Analysis of the Magnetically Confined Plasma Rocket

An electromagnetic calculation and the parameters of the magnet system of the magnetically confined plasma rocket were established. By using ANSYS code, it was found that the leakage rate depends on the current intensity of the magnet and the change of the magnet position.