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Protein Secondary Structure Prediction with Dynamic Self-Adaptation Combination Strategy Based on Entropy 被引量:1
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作者 Yuehan Du Ruoyu Zhang +4 位作者 Xu Zhang Antai Ouyang Xiaodong Zhang Jinyong Cheng Wenpeng Lu 《Journal of Quantum Computing》 2019年第1期21-28,共8页
The algorithm based on combination learning usually is superior to a singleclassification algorithm on the task of protein secondary structure prediction. However,the assignment of the weight of the base classifier us... The algorithm based on combination learning usually is superior to a singleclassification algorithm on the task of protein secondary structure prediction. However,the assignment of the weight of the base classifier usually lacks decision-makingevidence. In this paper, we propose a protein secondary structure prediction method withdynamic self-adaptation combination strategy based on entropy, where the weights areassigned according to the entropy of posterior probabilities outputted by base classifiers.The higher entropy value means a lower weight for the base classifier. The final structureprediction is decided by the weighted combination of posterior probabilities. Extensiveexperiments on CB513 dataset demonstrates that the proposed method outperforms theexisting methods, which can effectively improve the prediction performance. 展开更多
关键词 Multi-classifier combination ENTROPY protein secondary structure prediction dynamic self-adaptation
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