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Integrating phosphorus management and cropping technology for sustainable maize production
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作者 Haiqing Gong Yue Xiang +4 位作者 Jiechen Wu Laichao Luo Xiaohui Chen Xiaoqiang Jiao Chen Chen 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第4期1369-1380,共12页
Achieving high maize yields and efficient phosphorus(P)use with limited environmental impacts is one of the greatest challenges in sustainable maize production.Increasing plant density is considered an effective appro... Achieving high maize yields and efficient phosphorus(P)use with limited environmental impacts is one of the greatest challenges in sustainable maize production.Increasing plant density is considered an effective approach for achieving high maize yields.However,the low mobility of P in soils and the scarcity of natural P resources have hindered the development of methods that can simultaneously optimize P use and mitigate the P-related environmental footprint at high plant densities.In this study,meta-analysis and substance flow analysis were conducted to evaluate the effects of different types of mineral P fertilizer on maize yield at varying plant densities and assess the flow of P from rock phosphate mining to P fertilizer use for maize production in China.A significantly higher yield was obtained at higher plant densities than at lower plant densities.The application of single superphosphate,triple super-phosphate,and calcium magnesium phosphate at high plant densities resulted in higher yields and a smaller environmental footprint than the application of diammonium phosphate and monoammonium phosphate.Our scenario analyses suggest that combining the optimal P type and application rate with a high plant density could increase maize yield by 22%.Further,the P resource use efficiency throughout the P supply chain increased by 39%,whereas the P-related environmental footprint decreased by 33%.Thus,simultaneously optimizing the P type and application rate at high plant densities achieved multiple objectives during maize production,indicating that combining P management with cropping techniques is a practical approach to sustainable maize production.These findings offer strategic,synergistic options for achieving sustainable agricultural development. 展开更多
关键词 MAIZE plant density mineral phosphorus fertilizer META-ANALYSIS substance flow analysis
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Leveraging Artificial Intelligence to Achieve Sustainable Public Healthcare Services in Saudi Arabia: A Systematic Literature Review of Critical Success Factors
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作者 Rakesh Kumar Ajay Singh +3 位作者 Ahmed Subahi Ahmed Kassar Mohammed Ismail Humaida Sudhanshu Joshi Manu Sharma 《Computer Modeling in Engineering & Sciences》 2025年第2期1289-1349,共61页
This review aims to analyze the development and impact of Artificial Intelligence(AI)in the context of Saudi Arabia’s public healthcare system to fulfill Vision 2030 objectives.It is extensively devoted to AI technol... This review aims to analyze the development and impact of Artificial Intelligence(AI)in the context of Saudi Arabia’s public healthcare system to fulfill Vision 2030 objectives.It is extensively devoted to AI technology deployment relevant to disease management,healthcare delivery,epidemiology,and policy-making.However,its AI is culturally sensitive and ethically grounded in Islam.Based on the PRISMA framework,an SLR evaluated primary academic literature,cases,and practices of Saudi Arabia’s AI implementation in the public healthcare sector.Instead,it categorizes prior research based on how AI can work,the issues it poses,and its implications for the Kingdom’s healthcare system.The Saudi Arabian context analyses show that AI has increased the discreet prediction of diseases,resource management,and monitoring outbreaks during mass congregations such as hajj.Therefore,the study outlines critical areas for defining the potential for artificial intelligence and areas for enhancing digital development to support global healthcare progress.The key themes emerging from the review include Saudi Arabia:(i)the effectiveness of AI with human interaction for sustainable health services;(ii)conditions and quality control to enhance the quality of health care services using AI;(iii)environmental factors as influencing factors for public health care;(iv)Artificial Intelligence,and advanced decision-making technology for Middle Eastern health care systems.For policymakers,healthcare managers,and researchers who will engage with AI innovation,the review proclaims that AI applications should respect the country’s socio-cultural and ethical practices and pave the way for sustainable healthcare provision.More empirical research is needed on the implementation issues with AI,creating culturally appropriate models of AI,and finding new applications of AI to address the increasing demand for healthcare services in Saudi Arabia. 展开更多
关键词 Artificial intelligence public health services SUSTAINABILITY healthcare Saudi Arabia PRISMA
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Delineation of Site-Specific Management Zones Based on Temporal and Spatial Variability of Soil Electrical Conductivity 被引量:8
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作者 LI Yan SHI Zhou LI Feng 《Pedosphere》 SCIE CAS CSCD 2007年第2期156-164,共9页
A coastal saline field of 10.5 ha was selected as the study site and 122 bulk electrical conductivity (ECb) measurements were performed thrice in situ in the topsoil (0-20 cm) across the field using a hand held device... A coastal saline field of 10.5 ha was selected as the study site and 122 bulk electrical conductivity (ECb) measurements were performed thrice in situ in the topsoil (0-20 cm) across the field using a hand held device to assess the spatial variability and temporal stability of the distribution of soil electrical conductivity (EC), to identify the management zones using cluster analysis based on the spatiotemporal variability of soil EC, and to evaluate the probable potential for site-specific management in coastal regions with conventional statistics and geostatistical techniques. The results indicated high coefficients of variation for topsoil salinity over all the three samplings. The spatial structure of the salinity variability remained relatively stable with time. Kriged contour maps, drawn on the basis of spatial variance structure of the data, showed the spatial trend of the salinity distribution and revealed areas of consistently high or consistently low salinity, while a temporal stability map indicated stable and unstable regions. On the basis of the spatiotemporal characteristics, cluster analysis divided the site into three potential management zones, each with different characteristics that could have an impact on the way the field was managed. On the basis of the clearly defined management zones it was concluded that coastal saline land could be managed in a site-specific way. 展开更多
关键词 coastal saline field management zone soil electrical conductivity spatial variability temporal variability
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Interaction between climate and management on beta diversity components of vegetation in relation to soil properties in arid and semi-arid oak forests, Iran 被引量:3
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作者 Heydari MEHDI Aazami FATEMEH +4 位作者 Faramarzi MARZBAN Omidipour REZA Bazgir MASOUD Pothier DAVID Prévosto BERNARD 《Journal of Arid Land》 SCIE CSCD 2019年第1期43-57,共15页
This study aimed to investigate the interaction between regions with different climatic conditions(arid vs. semi-arid) and management(protected vs. unprotected) on the turnover and nestedness of vegetation in relation... This study aimed to investigate the interaction between regions with different climatic conditions(arid vs. semi-arid) and management(protected vs. unprotected) on the turnover and nestedness of vegetation in relation to physical, chemical and biological properties of soils in the Ilam Province of Iran. In each of the two regions, we sampled 8 sites(4 managed and 4 unmanaged sites) within each of which we established 4 circular plots(1000 m^2) that were used to investigate woody species, while two micro-plots(1 m×1 m) were established in each 1000-m^2 plot to analyze herbaceous species. In each sample unit, we also extracted three soil samples(0–20 cm depth) for measuring soil properties. The results indicated that the interaction between region and conservational management significantly affected the percent of canopy cover of Persian oak(Quercus brantii Linddl), soil respiration, substrate-induced respiration, as well as beta and gamma diversities and turnover of plant species. The percent of oak canopy cover was positively correlated with soil silt, electrical conductivity, available potassium, and alpha diversity, whereas it was negatively correlated with plant turnover. In addition, plant turnover was positively related to available phosphorus, while nestedness of species was positively related to organic carbon and total nitrogen. According to these results, we concluded that physical, chemical, and biological characteristics of limited ecological niche generally influenced plant diversity. Also, this study demonstrated the major contribution of the beta diversity on gamma diversity, especially in semi-arid region, because of the higher heterogeneity of vegetation in this area. 展开更多
关键词 CLIMATIC conditions conservation MANAGEMENT beta diversity OAK FORESTS physical-chemical property SEMI-ARID region
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Indigenous People’s Contribution to the Mitigation of Climate Variation, Their Perception, and Organizing Strategy for Sustainable Community Based Forest Resources Management in <i>Caraballo</i>Mountain, Philippines 被引量:3
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作者 Arneil G.Gabriel Teodora Luz S.Mangahas 《Open Journal of Ecology》 2017年第2期85-100,共16页
The focus of the study is to measure the level of awareness of Indigenous People on Climate Variation. It inquired into their observations and organizing strategy to cope with the early impacts of climate change on th... The focus of the study is to measure the level of awareness of Indigenous People on Climate Variation. It inquired into their observations and organizing strategy to cope with the early impacts of climate change on their socio-economic and cultural beliefs. The organization’s adaptation and mitigation practices to protect the environment are also discussed using as basis of analysis the multi-stakeholders framework of forest protection. The study documented and recognized the Indigenous Peoples contributions to the preservation and protection of forest resources in Caraballo mountain and a shift in paradigm to Indigenous People’s centered forest resources management is recommended. 展开更多
关键词 Indigenous People Community Based FOREST resources PARTICIPATORY FOREST Management Climate Change Case Study
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Discussion of college English classroom interaction under the multimedia environment 被引量:2
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作者 Liu Zhijun Pu Xiaowei 《International Journal of Technology Management》 2014年第4期8-10,共3页
This paper mainly takes the influence that the reform of university English teaching brings to the university English as a moment to study the college English classroom interaction problems under the multimedia enviro... This paper mainly takes the influence that the reform of university English teaching brings to the university English as a moment to study the college English classroom interaction problems under the multimedia environment, this paper mainly discusses types and features of the interaction, analyse the current situation of classroom interaction, so as to make suggestions for the teaching of college English classroom interaction. 展开更多
关键词 college English classroom interaction
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Application of CVAM-based management accounting in mobile telecommunication enterprises
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作者 WANG Ya-xing NI Wei-qing 《Journal of Modern Accounting and Auditing》 2010年第2期59-62,共4页
CVAM-based management accounting emphasizes that enterprises should make efforts not only to provide goods or service to customers but also to create value for customers. In practice, customer value should be measured... CVAM-based management accounting emphasizes that enterprises should make efforts not only to provide goods or service to customers but also to create value for customers. In practice, customer value should be measured reasonably first. Then according to its condition, enterprise can apply the CVAM-based management accounting method by improving management quality, perfecting costing planning, brand operation and business innovation to create value for customers thus achieving increase of corporate value as well as social value. 展开更多
关键词 customer value added management (CVAM) management accounting mobile telecommunication enterprises
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An Exploration of the Construction of Inner Driving Force of Cultural Education in Vocational Colleges
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作者 Maosen Jiang 《Journal of Contemporary Educational Research》 2020年第12期44-47,共4页
Cultural education is closely related to individual development and the needs for economic,social,and technological development,which,while aiming at improving students’overall professionalism,respects their subjecti... Cultural education is closely related to individual development and the needs for economic,social,and technological development,which,while aiming at improving students’overall professionalism,respects their subjective consciousness and initiative,highlights the development of personality and individual potential,and designs and improves educational activities that are characterized by cultivating people’s ability to make innovation,start a business,and form a healthy personality.Taking problems existing in the cultural education in vocational colleges as the cutin point,this paper explored the inner driving force of cultural education in the new era and tried to discuss the concept,objectives,content and mechanism of cultural education by pivoting to individual autonomy,expertise,and development goals,with the hope that the inner driving force of cultural education could be effectively carried out. 展开更多
关键词 Vocational colleges Cultural education Inner driving force Mechanism construction
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Strengthening the Financial Management of Coal Enterprises under the New Situation
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作者 Qian HUANG 《International Journal of Technology Management》 2015年第6期116-118,共3页
Along with China' s rapid economic development, the competition between enterprises is more and more intense, especially for the coal enterprises, and the market competition is fierce is predictable. If the coal ente... Along with China' s rapid economic development, the competition between enterprises is more and more intense, especially for the coal enterprises, and the market competition is fierce is predictable. If the coal enterprises want to be a healthy, sustainable development, it is necessary to strengthen the financial management and change the management mode according to the characteristics of the market competition. This paper mainly analyzes the present situation of financial management of coal enterprises in China and proposes further strengthening measures related to the financial management of coal enterprises. 展开更多
关键词 coal enterprises financial management current situation analysis COUNTERMEASURES
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Construction and Implementation of Knowledge System and Knowledge Management Platform of Software Enterprise
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作者 Yu Wenlong 《International Journal of Technology Management》 2013年第12期104-108,共5页
As a typical knowledge-intensive enterprise, knowledge has become the most important capital of the software enterprise, and the accumulation of knowledge, which makes the accumulation of knowledge especially importan... As a typical knowledge-intensive enterprise, knowledge has become the most important capital of the software enterprise, and the accumulation of knowledge, which makes the accumulation of knowledge especially important. Implementing knowledge management can integrate dispersed and unordered knowledge into organic and organizational knowledge system. Effective application and continuous enhancement of organizational knowledge system can from the core competence of software enterprise. For the characteristic that the software enterprise gives priority to software development, the paper uses the knowledge in the process of software development as the core (it is limited to time and energy and doesn' t involve the knowledge of the other departments), and develops the research on the construction of knowledge system of software enterprise. For the knowledge system, the paper constructs and implements a knowledge management platform supporting the operation and management. 展开更多
关键词 knowledge system knowledge management knowledge management platform
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Research on the Reform Model of China's Government Accounting Based on Performance Management
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作者 Juying HUANG 《International Journal of Technology Management》 2014年第9期57-59,共3页
Mueller said: "The environment has reflection on accounting; different cultural, economic, legal and political backgrounds produce different accounting systems." It's no exception with government accounting. Since... Mueller said: "The environment has reflection on accounting; different cultural, economic, legal and political backgrounds produce different accounting systems." It's no exception with government accounting. Since 1998, China's current budget accounting system has been acting as government accounting. Basically, it fulfilled the needs of relevant government accounting. The government accounting integrated with budget accounting. As time passes by, the current budget accounting can not meet the deepening globalization of the market economy nor the developing economic and political environment in terms of the definition of objectives, choices of basic accounting, offering of accounting information. In recent years, public finance reform, transformation of government functions, the public consciousness and other factors call for higher needs for the new government accounting. The current budget fails to provide enough government accounting information that the public need. In 2011, China started a pilot of performance management and performance budgeting in the country. The efficient use of public funds, the profits, and the effectiveness of public information draw more users' attention. It becomes more important for the govemrnent accounting larovidin~ information of performance evaluation. 展开更多
关键词 government accounting performance management reform model
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Analysis of using network resources to improve the effect of college English reading and writing teaching
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作者 Liu Zhijun Pu Xiaowei 《International Journal of Technology Management》 2014年第3期24-26,共3页
The difference between the college English reading and writing class which is supported by network and the traditional courses is that teachers and students use information technology to complete the study task and ac... The difference between the college English reading and writing class which is supported by network and the traditional courses is that teachers and students use information technology to complete the study task and achieve the teaching objectives in the process of teaching and learning. The role of the teacher is a guider and organizer, the teaching is student-centered teaching. This paper takes the teaching practice in reading and writing class as an example, explain how to use video file, screen demonstration, chat rooms, BBS, E-mail and other different multimedia network technology and approach, how to make full use of multimedia network resources in teaching college English reading and writing, how to improve the teaching effect. 展开更多
关键词 The network education College English Teaching mode
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Study on the Management Quality of China Woman Enterprisers
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作者 Guangzhu Liu Wenli Chen 《Chinese Business Review》 2003年第4期45-48,共4页
China women have formed their special personalities and characters different from men's. Enterprisers, who can prove equal to the task, must possess the management qualities. Women engaged in management work also nee... China women have formed their special personalities and characters different from men's. Enterprisers, who can prove equal to the task, must possess the management qualities. Women engaged in management work also need to possess the same management qualities. This paper discusses the advantages and disadvantages and help China women become excellent enterprisers. Management quality is a based condition possessed in management work, which includes the education degree, the level of some knowledge, the function of psychology, the skill, the experience, the health and so on. One of the important specific properties of management quality is the difference. The management qualities are connected with the management behaviors and performances. The advantages of the women enterprisers' management qualities are on three parts such as their vocational interests, values and personalities. The disadvantages are their psychological minds of their inferiority, dependency and mediocrity. 展开更多
关键词 China women enterpriser management quality psychology
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Application of Psychological Training in the Teaching of College Sports
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作者 Zhidong Yin Mei Meng +1 位作者 Min Li Jia Wang 《Journal of Zhouyi Research》 2014年第2期64-66,共3页
关键词 心理训练 体育教学 应用 高校 培训课程 咨询机构 训练课程 课程内容
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Requirement for Knowledge Management System
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作者 Ibrahim Abu AlSondos Faizuniah Pangil Siti Zubaidah Othman 《通讯和计算机(中英文版)》 2012年第3期263-275,共13页
关键词 知识管理系统 管理信息系统 数据检索 知识管理体系 竞争优势 知识共享 信息存储 定义
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Spatial Distribution Pattern and Influencing Factors of Bed-and-breakfasts(B&Bs)from the Perspective of Urban-rural Differences:A Case Study of Jiaodong Peninsula,China
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作者 WANG Xinyue MA Qian 《Chinese Geographical Science》 SCIE CSCD 2024年第4期752-763,共12页
There are significant differences between urban and rural bed-and-breakfasts(B&Bs)in terms of customer positioning,economic strength and spatial carrier.Accurately identifying the differences in spatial characteri... There are significant differences between urban and rural bed-and-breakfasts(B&Bs)in terms of customer positioning,economic strength and spatial carrier.Accurately identifying the differences in spatial characteristics and influencing factors of each type,is essential for creating urban and rural B&B agglomeration areas.This study used density-based spatial clustering of applications with noise(DBSCAN)and the multi-scale geographically weighted regression(MGWR)model to explore similarities and differences in the spatial distribution patterns and influencing factors for urban and rural B&Bs on the Jiaodong Peninsula of China from 2010 to 2022.The results showed that:1)both urban and rural B&Bs in Jiaodong Peninsula went through three stages:a slow start from 2010 to 2015,rapid development from 2015 to 2019,and hindered development from 2019 to 2022.However,urban B&Bs demonstrated a higher development speed and agglomeration intensity,leading to an increasingly evident trend of uneven development between the two sectors.2)The clustering scale of both urban and rural B&Bs continued to expand in terms of quantity and volume.Urban B&B clusters characterized by a limited number,but a higher likelihood of transitioning from low-level to high-level clusters.While the number of rural B&B clusters steadily increased over time,their clustering scale was comparatively lower than that of urban B&Bs,and they lacked the presence of high-level clustering.3)In terms of development direction,urban B&B clusters exhibited a relatively stable pattern and evolved into high-level clustering centers within the main urban areas.Conversely,rural B&Bs exhibited a more pronounced spatial diffusion effect,with clusters showing a trend of multi-center development along the coastline.4)Transport emerged as a common influencing factor for both urban and rural B&Bs,with the density of road network having the strongest explanatory power for their spatial distribution.In terms of differences,population agglomeration had a positive impact on the distribution of urban B&Bs and a negative effect on the distribution of rural B&Bs.Rural B&Bs clustering was more influenced by tourism resources compared with urban B&Bs,but increasing tourist stay duration remains an urgent issue to be addressed.The findings of this study could provide a more precise basis for government planning and management of urban and rural B&B agglomeration areas. 展开更多
关键词 urban-rural bed-and-breakfasts(B&Bs) spatiotemporal evolution density-based spatial clustering of applications with noise(DBSCAN)model multi-scale geographically weighted regression(MGWR) Jiaodong Peninsula China
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Enhancing transboundary natural tourism resources governance:unveiling the spatial pattern and its influencing factors
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作者 ZHANG Shengrui ZHANG Tongyan +1 位作者 JU Hongrun WANG Yingjie 《Journal of Mountain Science》 SCIE CSCD 2024年第3期973-986,共14页
Tourism resources that span provincial boundaries in China play a pivotal role in regional development,yet effective governance poses persistent challenges.This study addresses this issue by constructing a comprehensi... Tourism resources that span provincial boundaries in China play a pivotal role in regional development,yet effective governance poses persistent challenges.This study addresses this issue by constructing a comprehensive database of transboundary natural tourism resources(TNTR)through amalgamation of diverse data sources.Utilizing the Getis-Ord Gi^(*),kernel density estimation,and geographical detectors,we scrutinize the spatial patterns of TNTR,focusing on both named and unnamed entities,while exploring the influencing factors.Our findings reveal 7883 identified TNTR in China,with mountain tourism resources emerging as the predominant type.Among provinces,Hunan boasts the highest count,while Shanghai exhibits the lowest.Southern China demonstrates a pronounced clustering trend in TNTR distribution,with the spatial arrangement of biological landscapes appearing more random compared to geological and water landscapes.Western China,characterized by intricate terrain,exhibits fewer TNTR,concurrently unveiling a significant presence of unnamed natural tourism resources.Crucially,administrative segmentation influences TNTR development,generating disparities in regional goals,developmental stages and intensities,and management approaches.In response to these variations,we advocate for strengthening the naming of the unnamed transboundary tourism resources,constructing a geographic database of TNTR for government and establishing a collaborative management mechanism based on TNTR database.Our research contributes to elucidating the intricate landscape of TNTR,offering insights for tailored governance strategies in the realm of cross-provincial tourism resource management. 展开更多
关键词 Transboundary natural tourism resources(TNTR) Spatial difference Spatial autocorrelation Governance optimization China
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Assessment of Operational Performance in a Power Generation/Selling Integrated Company Using a Dynamic Proportional Adjustment Coefficient
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作者 Jingbin Wu Hongming Yang Sheng Xiang 《Energy Engineering》 EI 2024年第11期3263-3287,共25页
Currently,the operational performance assessment system in the power market primarily focuses on power generation and electricity retail companies,lacking a system tailored to the operational characteristics of power ... Currently,the operational performance assessment system in the power market primarily focuses on power generation and electricity retail companies,lacking a system tailored to the operational characteristics of power generation/selling integrated companies.Therefore,this article proposes an assessment index system for assessing the operational performance of a power generation/selling integrated company,encompassing three dimensions:basic capacity,development potential,and external environment.A dynamic proportional adjustment coefficient is designed,along with a subjective and objective weighting model for assessment indexes based on a combined weightingmethod.Subsequently,the operational performance of an integrated company is assessed using extension theory.The results in the case study demonstrate the feasibility and effectiveness of the proposed dynamic proportional adjustment coefficient. 展开更多
关键词 Power generation/selling integrated company dynamic proportional adjustment coefficient combined weighting extension theory assessment of operational performance
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Surface ozone in global cities:A synthesis of basic features,exposure risk,and leading meteorological driving factors
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作者 Jinmian Ni Jiming Jin +6 位作者 Yanwen Wang Bin Li Qian Wu Yanfei Chen Shenwen Du Yilin Li Chao He 《Geography and Sustainability》 CSCD 2024年第1期64-76,共13页
Long-term exposure to high surface ozone(O_(3))concentrations,a complex oxidative atmospheric pollutant,can adversely impact human health.Based on O_(3)monitoring data from 261 cities worldwide in 2020,generalized add... Long-term exposure to high surface ozone(O_(3))concentrations,a complex oxidative atmospheric pollutant,can adversely impact human health.Based on O_(3)monitoring data from 261 cities worldwide in 2020,generalized additive model(GAM)and spatial data analysis(SDA)methods were applied in this study to quantitatively evaluate the spatiotemporal distribution of O_(3)concentration,exposure risk,and dominant meteorological factors.Results indicated that over 40%of the cities worldwide were exposed to harmful O_(3)concentration ranges(40-60μg/m^(3)),with most cities distributed in China and India.Moreover,significant seasonal variations in global O_(3)concentrations were observed,presenting as summer(45.6μg/m^(3))>spring(47.3μg/m^(3))>autumn(38.0μg/m^(3))>winter(33.6μg/m^(3)).Exposure analysis revealed that approximately 12.2%of the population in 261 cities were exposed to an environment with high O_(3)concentrations(80-160μg/m^(3)),with about 36.32 million people in major countries.Thus,the persistent increase in high O_(3)levels worldwide is a critical factor contributing to threats to human health.Furthermore,GAM results indicated temperature,relative humidity,and wind speed as primary determinants of O_(3)variability.The synergy of meteorological factors is critical for understanding O_(3)changes.Our findings are important for enforcing robust air quality policies and mitigating public risk. 展开更多
关键词 Ozone pollution Spatiotemporal variation Exposure risk GAM Meteorological factors
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Emergence of taurine as a therapeutic agent for neurological disorders 被引量:2
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作者 Ashok Jangra Priyanka Gola +13 位作者 Jiten Singh Pooja Gond Swarnabha Ghosh Mahesh Rachamalla Abhijit Dey Danish Iqbal Mehnaz Kamal Punya Sachdeva Saurabh Kumar Jha Shreesh Ojha Dinesh Kumar Niraj Kumar Jha Hitesh Chopra Shing Cheng Tan 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第1期62-68,共7页
Taurine is a sulfur-containing,semi-essential amino acid that occurs naturally in the body.It alternates between inflammation and oxidative stress-mediated injury in various disease models.As part of its limiting func... Taurine is a sulfur-containing,semi-essential amino acid that occurs naturally in the body.It alternates between inflammation and oxidative stress-mediated injury in various disease models.As part of its limiting functions,taurine also modulates endoplasmic reticulum stress,Ca^(2+)homeostasis,and neuronal activity at the molecular level.Taurine effectively protects against a number of neurological disorders,including stro ke,epilepsy,cerebral ischemia,memory dysfunction,and spinal cord injury.Although various therapies are available,effective management of these disorders remains a global challenge.Approximately 30 million people are affected worldwide.The design of taurine fo rmation co uld lead to potential drugs/supplements for the health maintenance and treatment of central nervous system disorders.The general neuroprotective effects of taurine and the various possible underlying mechanisms are discussed in this review.This article is a good resource for understanding the general effects of taurine on various diseases.Given the strong evidence for the neuropharmacological efficacy of taurine in various experimental paradigms,it is concluded that this molecule should be considered and further investigated as a potential candidate for neurotherapeutics,with emphasis on mechanism and clinical studies to determine efficacy. 展开更多
关键词 antioxidant EPILEPSY γ-amino butyric acid neurodegenerative disorders NEUROPROTECTION oxidative stress spinal cord injury TAURINE
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