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Paracentesis following intravitreal drug injections in maintaining physiologic ocular perfusion pressure
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作者 Austin Bach Artur Filipowic +2 位作者 Aaron S. Gold Azeema Latiff Timothy G. Murray 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2017年第12期1925-1927,共3页
A retrospective analysis was performed of patients who received a paracentesis immediately following an intravitreal injection of bevacizumab or triamcinolone acetonide.These patients were previously diagnosed as havi... A retrospective analysis was performed of patients who received a paracentesis immediately following an intravitreal injection of bevacizumab or triamcinolone acetonide.These patients were previously diagnosed as having glaucoma,ocular hypertension,or had responded previously with sustained elevated intraocular pressure.Of 1661 procedures were performed.Totally 219(13%) of the injections were on phakic patients.A median(SD) of 210 μL(40 μL) of aqueous was removed during each paracentesis.There were no reported incidences of any complications.We propose performing a paracentesis immediately following intravitreal injections for patients at risk for ocular hypertension,glaucoma,and retinal vein or artery occlusion. 展开更多
关键词 anterior chamber paracentesis intravitreal injection intraocular pressure ocular perfusion pressure
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Spontaneous exudative retinal detachment in a patient with sturge-weber syndrome after taking arginine, a supplement for erectile dysfunction
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作者 Austin Bach Aaron S Gold +3 位作者 Victor M Villegas Andrea C Wildner Fiona J Ehlies Timothy G Murray 《Eye and Vision》 SCIE 2014年第1期46-50,共5页
Background:Patients with Sturge-Weber syndrome can have ipsilateral diffuse or circumscribed choroidal hemangiomas.These hemangiomas have been seen to undergo spontaneous exudative or hemorrhagic retinal detachments.T... Background:Patients with Sturge-Weber syndrome can have ipsilateral diffuse or circumscribed choroidal hemangiomas.These hemangiomas have been seen to undergo spontaneous exudative or hemorrhagic retinal detachments.There is no definitive treatment for these types of retinal detachments,but radiotherapy,photodynamic therapy,oral propranolol,pegaptinib and bevacizumab have been used.Case presentation:A 26-year-old male with Sturge-Weber Syndrome developed an exudative retinal detachment that occurred immediately after taking a supplement containing arginine.The patient was treated with intravitreal bevacizumab 1.25 mg in 0.05 ml solution.Resolution of the retinal detachment was seen after 4 treatments over a six-month period.Conclusions:Arginine and other medications that cause a release of nitric oxide may lead to intravascular leakage and exudative retinal detachments in patients who have a choroidal hemangioma. 展开更多
关键词 Sturge-Weber Syndrome Exudative retinal detachment Choroidal hemangioma Nitric oxide ARGININE
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