Phase Unwrapping (PU) is an ill-posed problem in Magnetic Resonance Elastography (MRE). The phase information is not usable until the phases are retrieved by using PU algorithms. In this present study, we attempt to d...Phase Unwrapping (PU) is an ill-posed problem in Magnetic Resonance Elastography (MRE). The phase information is not usable until the phases are retrieved by using PU algorithms. In this present study, we attempt to determine the ideal PU method for MRE using both phantom and volunteer psoas major (PM) muscle images. All the MRE experiments were carried out in Philips MRI (Achieva 3.0 T, Best, The Netherlands). A multi-echo gradient-echo MRE pulse sequence was employed and the four PU methods were considered based on their easy user platform. They are namely, Minimum Discontinuity (MD), Laplacian-Based Estimate (LBE), Region Growing (RG) and Dilate-Erode (DE) Propagate. Phantom images were successfully unwrapped by all four methods, whereas MD and LBE could only unwrap PM muscle images properly. RG and DE failed to unwrap the PM muscle images.展开更多
Magnetic resonance elastography (MRE) allows the quantitative assessment of the stiffness of tissues based on the tissue response to oscillatory shear stress. Shear wave displacements of the tissues are encoded as pha...Magnetic resonance elastography (MRE) allows the quantitative assessment of the stiffness of tissues based on the tissue response to oscillatory shear stress. Shear wave displacements of the tissues are encoded as phase shifts and converted to stiffness (elastogram). Generally, a partial volume effect occurs when different materials are encompassed on the same voxel. In MRE, however, the partial volume effect occurs even if the voxel is filled with the same materials because wave displacements due to vibrations are spatially distributed. The purpose of this study was to investigate how the partial volume effect can affect the phase shift and the elastogram in MRE. We assumed that the partial volume effect appears only in the slice thickness direction and performed a simulation and MRE experiment with various slice thicknesses (1 - 19 mm), two types of imaging plane (coronal and axial) and two types of vibration frequency (100 and 200 Hz). The results of the simulation and the MRE experiment were similar, and indicated that the phase shift and the elastogram changed variously depending on the slice thickness, the wave pattern and the vibration frequency, even if the voxel was filled with the same material. To reduce the partial volume effect, it is necessary to perform the MRE under the following conditions: Use a wave pattern which barely causes this artefact, a smaller voxel size and a lower vibration frequency.展开更多
文摘Phase Unwrapping (PU) is an ill-posed problem in Magnetic Resonance Elastography (MRE). The phase information is not usable until the phases are retrieved by using PU algorithms. In this present study, we attempt to determine the ideal PU method for MRE using both phantom and volunteer psoas major (PM) muscle images. All the MRE experiments were carried out in Philips MRI (Achieva 3.0 T, Best, The Netherlands). A multi-echo gradient-echo MRE pulse sequence was employed and the four PU methods were considered based on their easy user platform. They are namely, Minimum Discontinuity (MD), Laplacian-Based Estimate (LBE), Region Growing (RG) and Dilate-Erode (DE) Propagate. Phantom images were successfully unwrapped by all four methods, whereas MD and LBE could only unwrap PM muscle images properly. RG and DE failed to unwrap the PM muscle images.
文摘Magnetic resonance elastography (MRE) allows the quantitative assessment of the stiffness of tissues based on the tissue response to oscillatory shear stress. Shear wave displacements of the tissues are encoded as phase shifts and converted to stiffness (elastogram). Generally, a partial volume effect occurs when different materials are encompassed on the same voxel. In MRE, however, the partial volume effect occurs even if the voxel is filled with the same materials because wave displacements due to vibrations are spatially distributed. The purpose of this study was to investigate how the partial volume effect can affect the phase shift and the elastogram in MRE. We assumed that the partial volume effect appears only in the slice thickness direction and performed a simulation and MRE experiment with various slice thicknesses (1 - 19 mm), two types of imaging plane (coronal and axial) and two types of vibration frequency (100 and 200 Hz). The results of the simulation and the MRE experiment were similar, and indicated that the phase shift and the elastogram changed variously depending on the slice thickness, the wave pattern and the vibration frequency, even if the voxel was filled with the same material. To reduce the partial volume effect, it is necessary to perform the MRE under the following conditions: Use a wave pattern which barely causes this artefact, a smaller voxel size and a lower vibration frequency.
