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Relationship between rooting ability and endogenous phytohormone changes in successive continuous generation cuttings of Buxus sinica var. parvifolia, an endangered woody species in China 被引量:7
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作者 Huang Yan Ji Kong-shu Zhai Jin-ru 《Forestry Studies in China》 CAS 2007年第3期189-197,共9页
The objectives of this study were to investigate the effects of successive continuous generation (SCG) cuttings of Buxus sinica var. parvifolia on the rejuvenation of ortets at the hormone level, detect levels of in... The objectives of this study were to investigate the effects of successive continuous generation (SCG) cuttings of Buxus sinica var. parvifolia on the rejuvenation of ortets at the hormone level, detect levels of indoleacetic acid (IAA), abscisic acid (ABA), isopentenyladenosine (iPA), zeatin riboside (ZR) and gibberellin4 (GA4) during the rooting process of different generations by means of enzyme-linked immunosorbent assay (ELISA) technology and statistically analyze the rooting characteristics of cuttings. The results show that, the root systems of subsequent generations (generation 1998, 2000) developed satisfactorily, only a few initial generation (generation 1990, 1994) cuttings rooted and the root growth was inhibited. Around the period of callus formation and root projection through the epidermis, there was a marked, regular variation in the levels of IAA, ABA and GA4 between the initial generations and subsequent generations. 展开更多
关键词 Buxus sinica var. parvifolia PHYTOHORMONES successive continuous generation cutting REJUVENATION
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Narrative nursing for negative emotions in patients with acute pancreatitis:Based on model construction and application
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作者 Ling-Jun Zhou Juan Wu +4 位作者 Wen-Jie Huang Ai-Wu Shen Yu-Ping Yin Hai-Li Sun Yu-Ting Yuan 《World Journal of Psychiatry》 SCIE 2024年第11期1631-1640,共10页
BACKGROUND Acute pancreatitis(AP),as a common acute abdomen disease,has a high incidence rate worldwide and is often accompanied by severe complications.Negative emotions lead to increased secretion of stress hormones... BACKGROUND Acute pancreatitis(AP),as a common acute abdomen disease,has a high incidence rate worldwide and is often accompanied by severe complications.Negative emotions lead to increased secretion of stress hormones,elevated blood sugar levels,and enhanced insulin resistance,which in turn increases the risk of AP and significantly affects the patient's quality of life.Therefore,exploring the intervention effects of narrative nursing programs on the negative emotions of patients with AP is not only helpful in alleviating psychological stress and improving quality of life but also has significant implications for improving disease outcomes and prognosis.AIM To construct a narrative nursing model for negative emotions in patients with AP and verify its efficacy in application.METHODS Through Delphi expert consultation,a narrative nursing model for negative emotions in patients with AP was constructed.A non-randomized quasi-experimental study design was used in this study.A total of 92 patients with AP with negative emotions admitted to a tertiary hospital in Nantong City of Jiangsu Province,China from September 2022 to August 2023 were recruited by convenience sampling,among whom 46 patients admitted from September 2022 to February 2023 were included in the observation group,and 46 patients from March to August 2023 were selected as control group.The observation group received narrative nursing plan,while the control group was given with routine nursing.Self-rating anxiety scale(SAS),self-rating depression scale(SDS),positive and negative affect scale(PANAS),caring behavior scale,patient satisfaction scale and 36-item short form health survey questionnaire(SF-36)were used to evaluate their emotions,satisfaction and caring behaviors in the two groups on the day of discharge,1-and 3-month following discharge.RESULTS According to the inclusion and exclusion criteria,a total of 45 cases in the intervention group and 44 cases in the control group eventually recruited and completed in the study.On the day of discharge,the intervention group showed significantly lower scores of SAS,SDS and negative emotion(28.57±4.52 vs 17.4±4.44,P<0.001),whereas evidently higher outcomes in the positive emotion score,Caring behavior scale score and satisfaction score compared to the control group(P<0.05).Repeated measurement analysis of variance showed that significant between-group differences were found in time effect,inter-group effect and interaction effect of SAS and PANAS scores as well as in time effect and inter-group effect of SF-36 scores(P<0.05);the SF-36 scores of two groups at 3 months after discharge were higher than those at 1 month after discharge(P<0.05).CONCLUSION The application of narrative nursing protocols has demonstrated significant effectiveness in alleviating anxiety,ameliorating negative emotions,and enhancing satisfaction among patients with AP. 展开更多
关键词 Acute pancreatitis Negative emotions Narrative nursing model Adverse emotions Self-rating anxiety scale Selfrating depression scale
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竹柳枝丫材与小径材中密度纤维板的研究 被引量:11
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作者 何爽爽 王新洲 +2 位作者 邓玉和 衡利辰 张健 《林产工业》 北大核心 2015年第11期31-35,共5页
以竹柳枝丫材和3年生小径材为原料,采用脲醛树脂胶分别制备中密度纤维板。对比分析枝丫材与3年生小径材的密度、化学成分、纤维得浆率和纤维形态,研究施胶量和板材密度对竹柳纤维板物理力学性能的影响。结果表明:竹柳枝丫材的密度小于... 以竹柳枝丫材和3年生小径材为原料,采用脲醛树脂胶分别制备中密度纤维板。对比分析枝丫材与3年生小径材的密度、化学成分、纤维得浆率和纤维形态,研究施胶量和板材密度对竹柳纤维板物理力学性能的影响。结果表明:竹柳枝丫材的密度小于小径材的密度;竹柳枝丫材与小径材均有较高的综纤维素含量;竹柳枝丫材的纤维得浆率低于竹柳小径材;竹柳枝丫材、小径材纤维的壁腔比均小于1,是良好的纤维原料;竹柳枝丫材与小径材所制板材的性能均随着密度和施胶量的增加而明显提高;竹柳枝丫材所制纤维板的性能略低于小径材的,竹柳枝丫材所制纤维板在密度为0.75g/cm^3,施胶量为14%时,其物理力学性能可满足GB/T 11718—2009的要求;而竹柳小径材所制纤维板在密度为0.70g/cm^3,施胶量为14%时即可达到国标要求。 展开更多
关键词 枝丫材 小径材 竹柳 物理力学性能
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光电式电流互感器的现状和发展 被引量:11
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作者 平绍勋 HUANG Renshan 黄仁山 《高压电器》 CAS CSCD 北大核心 2001年第3期43-46,共4页
本文总结和分析了光电式电流互感器试运行的情况,并介绍了国内外这种互感器的研究现状。
关键词 光电式电流互感器 介质膜 罗戈夫斯基线圈 纵向调制 横向调制
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Comparisons in the global planetary boundary layer height obtained from COSMIC radio occultation,radiosonde,and reanalysis data 被引量:1
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作者 Jie Gu Yehui Zhang +1 位作者 Na Yang Rui Wang 《Atmospheric and Oceanic Science Letters》 CSCD 2021年第2期21-27,共7页
The global planetary boundary layer height(PBLH)estimated from 11 years(2007–17)of Integrated Global Radiosonde Archive(IGRA)data,Constellation Observing System for Meteorology,Ionosphere and Climate(COSMIC)soundings... The global planetary boundary layer height(PBLH)estimated from 11 years(2007–17)of Integrated Global Radiosonde Archive(IGRA)data,Constellation Observing System for Meteorology,Ionosphere and Climate(COSMIC)soundings,and European Center for Medium-Range Weather Forecasts(ECMWF)interim reanalysis(ERAInterim)data,are compared in this study.In general,the spatial distribution of global PBLH derived from ERAInterim is consistent with the one from IGRA,both at 1200 UTC and 0000 UTC.High PBLH occurs at noon local time,because of strong radiation energy and convective activity.There are larger differences between the results of COSMIC and the other two datasets.PBLHs derived from COSMIC are much higher than those from radiosonde and reanalysis data.However,PBLHs derived from the three datasets all exhibit higher values in the low latitudes and lower ones in the high latitudes.The latitudinal difference between IGRA and COSMIC ranges from−1700 m to−500 m,while it ranges from−500 m to 250 m for IGRA and ERA-Interim.It is found that the differences among the three datasets are larger in winter and smaller in summer for most studied latitudes. 展开更多
关键词 Planetary boundary layer height RADIOSONDE COSMIC REANALYSIS
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A Classification–Detection Approach of COVID-19 Based on Chest X-ray and CT by Using Keras Pre-Trained Deep Learning Models 被引量:10
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作者 Xing Deng Haijian Shao +2 位作者 Liang Shi Xia Wang Tongling Xie 《Computer Modeling in Engineering & Sciences》 SCIE EI 2020年第11期579-596,共18页
The Coronavirus Disease 2019(COVID-19)is wreaking havoc around the world,bring out that the enormous pressure on national health and medical staff systems.One of the most effective and critical steps in the fight agai... The Coronavirus Disease 2019(COVID-19)is wreaking havoc around the world,bring out that the enormous pressure on national health and medical staff systems.One of the most effective and critical steps in the fight against COVID-19,is to examine the patient’s lungs based on the Chest X-ray and CT generated by radiation imaging.In this paper,five keras-related deep learning models:ResNet50,InceptionResNetV2,Xception,transfer learning and pre-trained VGGNet16 is applied to formulate an classification-detection approaches of COVID-19.Two benchmark methods SVM(Support Vector Machine),CNN(Conventional Neural Networks)are provided to compare with the classification-detection approaches based on the performance indicators,i.e.,precision,recall,F1 scores,confusion matrix,classification accuracy and three types of AUC(Area Under Curve).The highest classification accuracy derived by classification-detection based on 5857 Chest X-rays and 767 Chest CTs are respectively 84%and 75%,which shows that the keras-related deep learning approaches facilitate accurate and effective COVID-19-assisted detection. 展开更多
关键词 COVID-19 detection deep learning transfer learning pre-trained models
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Effects of Density and Nitrogen Application Rate on Population Structure and Yield of Early-maturing Late Japonica Tongjing 981 被引量:1
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作者 Genyou ZHOU Bo WANG Hua XIA 《Agricultural Biotechnology》 CAS 2020年第4期92-98,150,共8页
The study adopted split block design with different treatment levels of density and fertilizer to investigate the growth period,population tiller dynamics,leaf area,dry matter accumulation,plant traits,panicle-grain s... The study adopted split block design with different treatment levels of density and fertilizer to investigate the growth period,population tiller dynamics,leaf area,dry matter accumulation,plant traits,panicle-grain structure,yielding ability and stress resistance of Tongjing 981 under different density and nitrogen fertilizer levels,so as to make clear the effects of different densities and nitrogen fertilizer levels on the population development and yield of Tongjing 981.The results showed that a too-low density was not conductive to the formation of sufficient number of panicles,and when the density was too high,it affected the number of grains per panicle and 1000-grain weight;and when nitrogen fertilizer was at a too-low level,it would restrict the population development,and a too-high nitrogen fertilizer easily led to the extension of the growth period and the aggravation of sheath blight.Reasonable density and fertilization level could make the development of individuals in Tongjing 981 population coordinated,and further help to establish a reasonable population structure,maintain a high leaf area and dry matter accumulation during the filling period,and balance the relationship of population dry matter weight with economic coefficient and panicle,grain and weight,thereby improving the population quality and yield of Tongjing 981. 展开更多
关键词 Tongjing 981 DENSITY Nitrogen application rate YIELD
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EXTERNAL USE OF BI YUAN NING IN 200 CASES OF NASOSINUSITIS AND RHINITIS
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作者 黄陈俊 缪葛 +2 位作者 吴自强 刘健 于格 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 1996年第2期105-107,共3页
Bi Yuan Ning, a sniffing preparation,was developed by Huang Xinglou, a veteranTCM doctor (1901 - 1984). based on his clin-ical experience of many years in diagnosisand treatment of nearly 1000 cases ofnasosinusitis an... Bi Yuan Ning, a sniffing preparation,was developed by Huang Xinglou, a veteranTCM doctor (1901 - 1984). based on his clin-ical experience of many years in diagnosisand treatment of nearly 1000 cases ofnasosinusitis and rhinitis. From March 1989to mid--march 1991, we also used Bi YuanNing to treated 200 cases with excellent cur-ative effects. 展开更多
关键词 取渊汤 千柏鼻炎片
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Analysis of Yield Components of Japonica Rice Tong Jing 981 under Different Density and Fertilization Conditions
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作者 Genyou ZHOU Hongyan YANG +1 位作者 Hua XIA Qikang CHEN 《Agricultural Science & Technology》 CAS 2017年第10期1921-1924,共4页
The yield and yield components of Japonica variety Tongjing 981 under different density and fertilization levels were studied through regression and correlation and path analysis. The results showed that the number of... The yield and yield components of Japonica variety Tongjing 981 under different density and fertilization levels were studied through regression and correlation and path analysis. The results showed that the number of panicles per unit area, number of filled grains per panicle and 1 000-grain weight all had very significant yield increasing effects, and the number of panicles per unit area played a leading role. However, the yield increasing effects of the number of panicles per unit area and number of filled grains per panicle are equally important when the basic seedlings are more or the N fertilizer application rate is large. In practical production, a major factor should be determined among the yield components, and rational cultivation measures should be taken accordingly, to improve yield. 展开更多
关键词 Tongjing 981 Basic seedling N application rate Number of panicle per unit area Number of filled grains per panicle 1 000-grain weight Yield
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Effects of Different Antibiotics Substitutes on Production Performance of Fattening Pigs
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作者 Sha Wenfeng Zhu Juan +2 位作者 Gu Yongjian Zhang Ruixiang Shen Jun 《Animal Husbandry and Feed Science》 CAS 2016年第5期275-277,共3页
[ Objective ] The aim was to discuss effects of different antibiotics substitutes on production performance of fattening pigs, and to lay a foundation for development and application of antibiotics-free pig feed. [ Me... [ Objective ] The aim was to discuss effects of different antibiotics substitutes on production performance of fattening pigs, and to lay a foundation for development and application of antibiotics-free pig feed. [ Method ] By adding 100 mg/kg compound probiotics, 100 mg/kg compound enzyme preparation, 500 and 1 000 mg/kg eu-commin in the basal diet, binary hybrid pigs weighing about 15 kg were reared for 102 d, and the feed added with 300 mg/kg colistin sul- fate was used as control. [ Result] Using compound prebiotics and compound enzyme preparation to substitute antibiotics had no adverse effects on daily weight gain, daily feed intake and feed gain ratio of 15 -90 kg fattening pigs; using eu-commin to substitute antibiotics had no adverse effect on daily weight gain, daily feed intake and feed gain ratio of 15 - 30 kg fattening pigs, but had significant influence on daily weight gain of 30 - 90 kg fattening pigs ( P 〈 0.05 ). [ Conclusion] It is feasible to develop antibiotics-free pig feed by using new type of green environmental-friendly additive instead of antibiotics. 展开更多
关键词 Antibiotics substitutes Fattening pig Production performance
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Study on the relationship between serum PCT, CRP level and atypical lymphocyte ratio and severity of respiratory virus infection
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作者 Yi Cheng Jin-Xiang Liu 《Journal of Hainan Medical University》 2018年第21期5-8,共4页
Objective: To investigate the relationship between serum procalcitonin (PCT) and C-reactive protein (CRP) combined with the proportion of atypical lymphocytes and severity of respiratory virus infection. Methods: A to... Objective: To investigate the relationship between serum procalcitonin (PCT) and C-reactive protein (CRP) combined with the proportion of atypical lymphocytes and severity of respiratory virus infection. Methods: A total of 113 children with respiratory infection in our hospital from January 2018 to August 2018 were enrolled. According to the type of infection, they were divided into bacterial infection group (n=38) and virus infection group (n=52), 60 healthy children were selected as the control group. Serum PCT, CRP and atypical lymphocyte ratios were measured in each group, and the relationship between them and the severity of the disease was analyzed. Results: The serum CRP and PCT in the bacterial infection group were significantly higher than those in the virus-infected group and the control group. While The ratio of atypical lymphocytes in the virus-infected group was significantly higher than that in the bacterial-infected group and the control group;The serum PCR, CRP and atypical lymphocyte ratio gradually increased with the severity of the disease, the difference was statistically significant. Pearson correlation analysis showed that serum PCT, CRP content and atypical lymphocyte ratio were significantly positively correlated with the severity of the disease. The positive rate of PCR and CRP in the bacterial infection group was significantly higher than that in the virus infection group. The positive rate of heterotypic lymphocyte ratio was significantly lower than that in the virus infection group. Conclusion: The detection of serum PCT and CRP levels has a good diagnostic value for bacterial respiratory infections. The ratio of atypical lymphocytes can be used as a preliminary aid in the diagnosis of respiratory virus infection-related diseases. The combination of the two is of great significance for the clinical diagnosis of children with respiratory infections. 展开更多
关键词 PROCALCITONIN C-reactive protein ATYPICAL LYMPHOCYTES RESPIRATORY infection
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Research on the effect of kunfukang capsule on improving uterine microcirculation in patients with sequelae of pelvic inflammatory disease and its influence on levels of crp, gm-csf and mcp-1 in peripheral blood
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作者 Yan-Yan Ding Hao-Jue Wang 《Journal of Hainan Medical University》 2019年第12期57-61,共5页
Objective:To investigate the clinical effect of kunfukang capsule on improving uterine microcirculation in patients with sequelae of pelvic inflammatory disease, and to observe its influence on levels of CRP, GM-CSF a... Objective:To investigate the clinical effect of kunfukang capsule on improving uterine microcirculation in patients with sequelae of pelvic inflammatory disease, and to observe its influence on levels of CRP, GM-CSF and MCP-1 in peripheral blood.Methods: 126 patients with pelvic inflammatory disease sequelae admitted to our hospital from January 2017 to June 2018 were selected and divided into control group and observation group with 63 cases in each group according to the random number table method. Patients in the control group were given azithromycin tablets orally, while patients in the observation group were treated with kunfukang capsule on the basis of control group,7days for a course of treatment, 4 courses of continuous treatment. The purpose of this study was to compare the clinical effects of treatment between the two groups, evaluate the TCM syndrome score, observe the levels of CRP, GM-CSF and MCP-1 in uterine microcirculation and peripheral blood, and record the adverse reactions of patients during treatment.Results: The effective rate of 90.48% in the observation group was significantly higher than that in the control group of 77.78%(P<0.05). After treatment, the total score of TCM syndromes was significantly lower than that in the control group (P<0.05). The improvement of uterine microcirculation was more obvious, and the PI and RI were significantly decreased compared with the control group, while Vs, Vd and Vm were increased compared with the control group (P<0.05). The levels of CRP, GM-CSF and MCP-1 in peripheral blood were significantly lower than those in the control group (P<0.05). During the treatment, the adverse reaction rate of 7.94% in the observation group was significantly lower than that of the control group of 25.40% (P<0.05).Conclusion: Kun fu kang capsule combined with azithromycin is beneficial to reduce pelvic mass in sequelae of pelvic inflammatory disease and alleviate clinical symptoms. The mechanism may be related to improving the status of uterine microcirculation and inhibiting CRP, GM-CSF and MCP-1 levels in peripheral blood to reduce inflammatory infiltration of pelvic tissue, which is safe and reliable. 展开更多
关键词 Pelvic inflammatory disease sequelae Kunfukang CAPSULE UTERINE MICROCIRCULATION CRP GM-CSF MCP-1
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The Effection Analysis of Geotechnical Investigation on Foundation Pit Supporting Construction
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作者 Weiwei Xu 《Frontiers Research of Architecture and Engineering》 2021年第1期26-31,共6页
With the continuous development of the construction industry,the density of engineering construction and the difficulty of underground construction are also increasing.As an important construction protection measure,f... With the continuous development of the construction industry,the density of engineering construction and the difficulty of underground construction are also increasing.As an important construction protection measure,foundation pit support construction is widely used in underground construction.Starting from the characteristics of foundation pit support construction,this paper analyzes the influence of geotechnical investigation on foundation pit support construction,and analyzes the problems that need to be paid attention to in the survey process. 展开更多
关键词 Geotechnical investigation Foundation pit support Construction effect
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Effect of dexmedetomidine on stress indicators, neurological function and related factors in patients after spinal surgery
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作者 Xiao-Li Cui Cai-Feng Zhang +2 位作者 Yun Wang Mei-Juan Qian Hong-Sheng Yan 《Journal of Hainan Medical University》 2019年第7期30-33,共4页
Objective: To investigate the effect of dexmedetomidine on stress index, neurological function and related factors in patients after spinal surgery. Methods: A total of 120 patients who underwent spinal surgery in our... Objective: To investigate the effect of dexmedetomidine on stress index, neurological function and related factors in patients after spinal surgery. Methods: A total of 120 patients who underwent spinal surgery in our hospital from June 2015 to June 2018 were collected and randomly divided into the control group and the observation group, 60 cases in each group. The patients in the control group were given sufentanil for analgesia, while the patients in the observation group were given dexmedetomidine combined with sufentanil for analgesia. Before and after operation, the levels of adrenocortical hormone (ACTH), cortisol (Cor), serum insulin (Ins), peripheral blood nerve growth factor (NGF), neurotrophic factor (BDNF), adrenaline (Adr), norepinephrine (NE), endothelin-1 (ET-1), tumor necrosis factor-α(TNF-α) and C reactive protein (CRP) were measured and compared between the patients in the two groups. Result: The serum levels of ACTH, Cor, Ins, Adr, NE, ET-1, TNF-α and CRP of patients in the control group and observation group were significantly increased after operation, while the serum levels of ACTH, Cor, Ins, Adr, NE, ET-1, TNF-α and CRP of patients in the observation group were significantly lower than those in the control group. The serum levels of NGF and BDNF of patients in the observation group were significantly increased after operation. The serum levels of NGF and BDNF of patients in the control group were significantly decreased. Conclusion: Dexmedetomidine combined with sufentanil for spinal surgery analgesia can effectively control the levels of post-operative stress and reduce the influence on neurological function of patients. It can be used for clinical promotion. 展开更多
关键词 DEXMEDETOMIDINE SUFENTANIL SPINAL surgery Stress state NEUROLOGICAL function INFLAMMATORY factors
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Structural Characterization of Carbon-implanted GaSb
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作者 SHEN Guiying ZHAO Youwen HE Jianjun 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS CSCD 2023年第5期969-973,共5页
Ion implantation induced damage in GaSb and its removal by rapid thermal annealing(RTA)have been investigated by Raman spectroscopy.The evolution of the Raman modes as a function of implantation fluence,annealing temp... Ion implantation induced damage in GaSb and its removal by rapid thermal annealing(RTA)have been investigated by Raman spectroscopy.The evolution of the Raman modes as a function of implantation fluence,annealing temperature and time has been analyzed.Results indicate that a lattice quality that is close to as-grown GaSb has been obtained by annealing the implanted samples at 500℃for 45 s.However,consequent surface analyses by scanning electron microscope(SEM)and atomic force microscope(AFM)show that a heavily perturbed layer contains voids due to the outdifiusion of Sb atoms on the surface remains.Mechanism of the damage recovery and the structure of the implanted layer are discussed based on the experimental results. 展开更多
关键词 Ion implantation Raman spectroscopy GASB RTA
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Motivations and the Second Language Learning
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作者 LI Ya-qin 《海外英语》 2013年第19期13-14,共2页
This paper explores a general theory of Second Language Learning.In this paper,the author tries to illustrate some thing about motivations which help us develop more effective approaches to learn a second Language.Sel... This paper explores a general theory of Second Language Learning.In this paper,the author tries to illustrate some thing about motivations which help us develop more effective approaches to learn a second Language.Self-confidence,experi ence of success and satisfaction,good relationships among Learners and relationships among teacher and students are believed to have a solid connection with motivation.They are also correlated with each other in the process of motivation development. 展开更多
关键词 MOTIVATION SELF-CONFIDENCE EXPERIENCE of SUCCESS a
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Analysis of symbolism in Jack London's A Piece of Steak—A brief analysis on contradictory beliefs of Jack London
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作者 ZHOU Yao 《海外英语》 2014年第5X期213-215,共3页
A Piece of Steak is one of Jack London’s short stories in which lots of symbolism usage could be found.Jack London is an American realistic writer who did not receive much formal education.However,he loved reading an... A Piece of Steak is one of Jack London’s short stories in which lots of symbolism usage could be found.Jack London is an American realistic writer who did not receive much formal education.However,he loved reading and was greatly influenced by Spenser,Darwin,Nietzsche,Karl Marx and etc.The influences made Jack London form contradictory beliefs which were shown in this short story. 展开更多
关键词 SYMBOLISM CONTRADICTORY ageing
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A novel preparation of Panax japonicas with high bioequivalence of ginsenoside Rg3
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作者 Xinyu Shen Xingchen Wang +6 位作者 Caihong Gu Feng Yan Bo Pan Lizeng Gao Bingchun Yan Qi Liu Rong Hu 《Journal of Chinese Pharmaceutical Sciences》 CAS CSCD 2019年第9期650-664,共15页
In the present study,we aimed to prepare Panax japonicus tablets and carry out quality inspection.Panax japonicus tablets were prepared by ultrafine pulverization-wet granulation,and quality inspection was carried out... In the present study,we aimed to prepare Panax japonicus tablets and carry out quality inspection.Panax japonicus tablets were prepared by ultrafine pulverization-wet granulation,and quality inspection was carried out according to Pharmacopoeia regulations.The plasma concentration of animals with self-made Panax japonicus tablets or ginsenoside Rg3 in single-dose intragastric administration was determined by high-performance liquid chromatography(HPLC).The pharmacokinetic parameters and relative bioavailability were calculated by DAS 2.0 software.The quality inspection of self-made Panax japonicus tablets met the requirements of Chinese Pharmacopoeia(2015 edition),and this preparation had high bioequivalence of ginsenoside Rg3.The preparation of Panax japonicus tablets was reasonable and highly qualified.Moreover,this new Panax japonicus preparation showed better profiles in oral absorption and utilization.This study provided evidence for the industrial production and clinical application of Panax japonicus tablets. 展开更多
关键词 Panax japonicas tablets Tablet quality Ginsenoside Rg3 BIOEQUIVALENCE
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Development of ovalbumin implants with different spatial configurations for treatment of peripheral nerve injury
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作者 Tiantian Zheng Hongxia Gao +5 位作者 Yaqiong Liu Shaolan Sun Wenchao Guan Linliang Wu Yumin Yang Guicai Li 《Bioactive Materials》 SCIE CSCD 2024年第5期401-415,共15页
Peripheral nerve injury(PNI)seriously affects the health and life of patients,and is an urgent clinical problem that needs to be resolved.Nerve implants prepared from various biomaterials have played a positive role i... Peripheral nerve injury(PNI)seriously affects the health and life of patients,and is an urgent clinical problem that needs to be resolved.Nerve implants prepared from various biomaterials have played a positive role in PNI,but the effect should be further improved and thus new biomaterials is urgently needed.Ovalbumin(OVA)contains a variety of bioactive components,low immunogenicity,tolerance,antimicrobial activity,non-toxicity and biodegradability,and has the ability to promote wound healing,cell growth and antimicrobial properties.However,there are few studies on the application of OVA in neural tissue engineering.In this study,OVA implants with different spatial structures(membrane,fiber,and lyophilized scaffolds)were constructed by casting,electrospinning,and freeze-drying methods,respectively.The results showed that the OVA implants had excellent physicochemical properties and were biocompatible without significant toxicity,and can promote vascularization,show good histocompatibility,without excessive inflammatory response and immunogenicity.The in vitro results showed that OVA implants could promote the proliferation and migration of Schwann cells,while the in vivo results confirmed that OVA implants(the E5/70%and 20 kV 20μL/min groups)could effectively regulate the growth of blood vessels,reduce the inflammatory response and promote the repair of subcutaneous nerve injury.Further on,the high-throughput sequencing results showed that the OVA implants up-regulated differential expression of genes related to biological processes such as tumor necrosis factor-α(TNF-α),phosphatidylinositide 3-kinases/protein kinase B(PI3K-Akt)signaling pathway,axon guidance,cellular adhesion junctions,and nerve regeneration in Schwann cells.The present study is expected to provide new design concepts and theoretical accumulation for the development of a new generation of nerve regeneration implantable biomaterials. 展开更多
关键词 OVALBUMIN Casting method ELECTROSPINNING Freeze drying Nerve scaffold Peripheral nerve injury
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Clinical observation on electroacupuncture plus long-snake moxibustion for rheumatoid arthritis due to kidney deficiency and cold coagulation 被引量:7
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作者 Xie Yu-ying Li Si-si Ben Yue-hong 《Journal of Acupuncture and Tuina Science》 CSCD 2020年第6期467-473,共7页
Objective:To observe the clinical efficacy of electroacupuncture(EA)plus long-snake moxibustion for rheumatoid arthritis(RA)due to kidney deficiency and cold coagulation.Methods:A total of 60 patients in active stage ... Objective:To observe the clinical efficacy of electroacupuncture(EA)plus long-snake moxibustion for rheumatoid arthritis(RA)due to kidney deficiency and cold coagulation.Methods:A total of 60 patients in active stage of RA were randomly divided into an observation group and a control group,with 30 cases in each group.Patients in the control group took methotrexate tablets and nimesulide dispersible tablets orally for treatment,while those in the observation group received additional treatment of EA plus long-snake moxibustion.Both groups were treated for 12 weeks.The post-treatment changes in symptomatic grading and quantifying score,disease activity score with 28 joint counts(DAS28),and inflammatory indicators erythrocyte sedimentation rate(ESR)and C-reactive protein(CRP)were observed,and the efficacy was evaluated.Results:The total effective rate in the observation group was 89.9%,versus 76.6%in the control group,and there was a significant difference in the total effective rate between the two groups(P<0.05).After treatment,the symptomatic grading and quantifying score and DAS28 in both groups were significantly improved(all P<0.05),and the improvements in the observation group were more significant than those in the control group(both P<0.05).Besides,there were 11 cases with low disease activity index(DAI)and in remission in the observation group versus 5 cases in the control group,showing a statistically significant between-group difference(P<0.05).The ESR and CRP scores in both groups were significantly reduced after treatment(all P<0.05),also showing statistically significant between-group differences(both P<0.05).Conclusion:The efficacy of additional EA plus long-snake moxibustion based on oral medications for RA due to kidney deficiency and cold coagulation is better than that of the oral medications alone. 展开更多
关键词 Acupuncture Therapy ELECTROACUPUNCTURE Acupuncture-moxibustion Therapy Moxibustion Therapy Indirect Moxibustion Arthritis Rheumatoid Syndrome Differentiation Treatment
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