In the era of rapid development of informatization,the informatization construction of national higher vocational colleges has been in the period of application deepening.China's education system is deepening to t...In the era of rapid development of informatization,the informatization construction of national higher vocational colleges has been in the period of application deepening.China's education system is deepening to the development of mass education,and higher vocational colleges'adult continuing education plays a great role for the realization of education popularization.With the continuous expansion of continuing education enrollment scale,the diversified development of education mode,the higher complexity of continuing education management and the increase of management workload,the traditional management method has gradually become unapplicable.Higher vocational colleges can greatly improve the management level by promoting the informatization of education management according to their own professional or regional advantages.展开更多
Based on the needs of personnel training in the sustainable development of enterprises, this paper has researched that cultivating high-quality technical personnel of enterprises is the requirements of the sustainable...Based on the needs of personnel training in the sustainable development of enterprises, this paper has researched that cultivating high-quality technical personnel of enterprises is the requirements of the sustainable development of enterprises. Universities in the continuing educational process should establish the basic principles of cultivating high-quality technical personnel of enterprises, and developing continuing education in universities and actively exploring the training mode of high-quality technical personnel of enterprises are proposed.展开更多
Confucius's "No Child Left Behind" education ideology which was put forward two thousand years ago reflected the importance of education for educators and the simple pursuit of educational equity at that time. Educ...Confucius's "No Child Left Behind" education ideology which was put forward two thousand years ago reflected the importance of education for educators and the simple pursuit of educational equity at that time. Education Fair is the current composition content of China's basic education dream. Practicing "No Child Left Behind" education is the cornerstone to achieve China's fair education dream. Making implementing continuing education in order to achieve "No Child Left Behind" equitable education as a research issue, based on analyzing the status and problems of educational equity issues under the perspective of NCLB, the author explored the realistic way through multi-channel and diverse continuing education to achieve "No Child Left Behind "equitable education.展开更多
Recently, the scale of higher education for adults is expanding and at the same time, the teaching quality is declining, which has been increasingly focused on. In order to improve the teaching quality, at first, it i...Recently, the scale of higher education for adults is expanding and at the same time, the teaching quality is declining, which has been increasingly focused on. In order to improve the teaching quality, at first, it is necessary to build up a set of integrative and complete teaching quality evaluation system, which is composed of class, course major and college respectively from the aspects of learning and teaching because of the particularity of the students and teaching modes of higher education for adults.展开更多
From data published by the Hong Kong SAR(HKSAR)government in their two sole fisheries surveys of 2006 and 2016/2017,the current authors produced regional maps using spatial interpolation to more accurately describe an...From data published by the Hong Kong SAR(HKSAR)government in their two sole fisheries surveys of 2006 and 2016/2017,the current authors produced regional maps using spatial interpolation to more accurately describe and estimate the geographic coverage of changes in fishing production in Hong Kong waters since the ground trawl ban of 2012 December 31st.These suggest the fishing industry has adapted to smaller craft,and that fishing production increased in several areas in the period after the ground trawl ban came into effect.In addition,the maps enable a smoother assessment to be made of the geospatial changes in fishing production which have occurred since the ground trawl ban and suggest a‘workaround’by fishermen.In particular,small fishing craft known as sampans are able to take advantage by being more suitable vessels for areas such as narrower or shallower bays.Marine plastics pollution is also a proxy indicator of these activities,as evidenced by discarded fishing gear that includes plastic nets,floats,and other fishing boat equipment.展开更多
BACKGROUND Hepatic cystic and alveolar echinococcosis coinfections,particularly with concurrent abscesses and sinus tract formation,are extremely rare.This article presents a case of a patient diagnosed with this uniq...BACKGROUND Hepatic cystic and alveolar echinococcosis coinfections,particularly with concurrent abscesses and sinus tract formation,are extremely rare.This article presents a case of a patient diagnosed with this unique presentation,discussing the typical imaging manifestations of both echinococcosis types and detailing the diagnosis and surgical treatment experience thereof.CASE SUMMARY A 39-year-old Tibetan woman presented with concurrent hepatic cystic and alveolar echinococcosis,accompanied by abdominal wall abscesses and sinus tract formation.Initial conventional imaging examinations suggested only hepatic cystic echinococcosis,but intraoperative and postoperative pathological examination revealed the coinfection.Following radical resection of the lesions,the patient’s condition improved,and she was discharged soon thereafter.Subsequent outpatient follow-ups confirmed no recurrence of the hydatid lesion and normal surgical wound healing.Though mixed hepatic cystic and alveolar echinococcosis with abdominal wall abscesses and sinus tract formations are rare,the general treatment approach remains consistent with that of simpler infections of alveolar echinococcosis.CONCLUSION Lesions involving the abdominal wall and sinus tract formation,may require radical resection.Long-term prognosis includes albendazole and follow-up examinations.展开更多
In the article,we prove that the double inequalities Gp[λ1a+(1-λ1)b,λ1 b+(1-λ1)a]A1-p(a,b)<T[A(a,b),G(a,b)]<Gp[μ1 a+(1-μ1)b,μ1b+(1-μ1)a]A1-p(a,b),Cs[λ^(2) a+(1-λ2)b,λ2 b+(1-λ2)a]A1-s(a,b)<T[A(a,b)...In the article,we prove that the double inequalities Gp[λ1a+(1-λ1)b,λ1 b+(1-λ1)a]A1-p(a,b)<T[A(a,b),G(a,b)]<Gp[μ1 a+(1-μ1)b,μ1b+(1-μ1)a]A1-p(a,b),Cs[λ^(2) a+(1-λ2)b,λ2 b+(1-λ2)a]A1-s(a,b)<T[A(a,b),Q(a,b)]<Cs[μ2 a+(1-μ2)b,μ2 b+(1-μ2)a]A1-p(a,b)hold for all a,b>0 with a≠b if and only ifλ1≤1/2-(1-(2/π)2/p)1/2/2,μ1≥1/2-(2p)1/2/(4 p),λ2≤1/2+(2(3/(2 s)(E(21/2/2)/π)1/s)-1)1/2/2 andμ2≥1/2+s1/2/(4 s)ifλ1,μ1∈(0,1/2),λ2,μ2∈(1/2,1),p≥1 and s≥1/2,where G(a,b)=(ab)1/2,A(a,b)=(a+b)/2,T(a,b)=∫0π/2(a2 cos2 t+b2 sin2)1/2 tdt/π,Q(a,b)=((a2+b2)/2)1/2,C(a,b)=(a2+b2)/(a+b)and E(r)=∫0π/2(1-r^(2) sin^(2))1/2 tdt.展开更多
Serum pharmacochemistry of traditional Chinese medicine has become a more accurate and rapidly developing reasonable way to analyze the effective material basis of traditional Chinese medicine in recent years. Through...Serum pharmacochemistry of traditional Chinese medicine has become a more accurate and rapidly developing reasonable way to analyze the effective material basis of traditional Chinese medicine in recent years. Through this method, we can select very complex Chinese medicine components and clarify the effective substances consistent with the main functions, and then separate and purify effective ingredients in traditional Chinese medicine, so as to explain the material basis of the drug effect and prove the rationality and principle of action of Chinese medicine compounds. It can show the multi-component and multi-target characteristic of traditional Chinese medicine, and after analyzing the migrating components of serum, we can explore the direct effective substances that act on the patient’s body, so as to accelerate and accurately complete the in-depth study of the effective substances of Chinese medicine.展开更多
According to the different types of liver damage,there should also be different Chinese medicine and dose for different degrees of treatment and protection.This paper studies the Chinese medicine treatment of differen...According to the different types of liver damage,there should also be different Chinese medicine and dose for different degrees of treatment and protection.This paper studies the Chinese medicine treatment of different types of liver injury,and is expected to provide a reference for the further application of Chinese medicine in liver injury.展开更多
Objective:To determine the effect of an immunosuppressive active component (periploside A) isolated from the stem bark of Periplocae Cortex (Periploca sepium Bge.),a Chinese medicinal herb used in the treatment of rhe...Objective:To determine the effect of an immunosuppressive active component (periploside A) isolated from the stem bark of Periplocae Cortex (Periploca sepium Bge.),a Chinese medicinal herb used in the treatment of rheumatoid arthritis for centuries in China,on positive selection of thymocytes in vitro.Methods:Female C57BL/6 mice at 6 weeks of age were housed in specific pathogen-free conditions.Double-positive thymocytes from C57BL/6 mice were induced into positive selection in vitro with or without periploside A treatment.Cell viability and expression of CD69,CD4,and CD8 were analyzed by flow cytometry.Results:Flow cytometric examination of thymocyte populations revealed that the percentage of CD8+ single-positive thymocytes was decreased by periploside A upon differentiation induced by an anti-CD3 antibody.However,the percentage of CD4+ single-positive thymocytes was decreased by periploside A upon differentiation induced by phorbol 12-myristate 13-acetate/ionomycin.Expression of CD69 plays a major role in prohibiting differentiation of thymocytes.Treatment with periploside A decreased CD69 expression in thymocytes.Conclusion:These results demonstrate that periploside A influences positive selection of thymocytes in vitro.展开更多
The aim of this paper is to seek the numerical solution of a class of variable order fractional integral-differential equation in terms of Bernstein polynomials.The fractional derivative is described in the Caputo sen...The aim of this paper is to seek the numerical solution of a class of variable order fractional integral-differential equation in terms of Bernstein polynomials.The fractional derivative is described in the Caputo sense.Four kinds of operational matrixes of Bernstein polynomials are introduced and are utilized to reduce the initial equation to the solution of algebraic equations after dispersing the variable.By solving the algebraic equations,the numerical solutions are acquired.The method in general is easy to implement and yields good results.Numerical examples are provided to demonstrate the validity and applicability of the method.展开更多
The pure land conviction was quite prevalent in the Peace Time when The Tale of Genji was published.Murasaki Shikibuestablished the pure land conviction in The Tale of Genjialong with the skeleton which expands from t...The pure land conviction was quite prevalent in the Peace Time when The Tale of Genji was published.Murasaki Shikibuestablished the pure land conviction in The Tale of Genjialong with the skeleton which expands from the decline of aristocracy to the consciousness of the mappōand the eschatology,and then to the abominate toward impure land as well as the desire for pure land.Besides,she assimilated the doctrines and aesthetics from the pure land classics as well as inaugurated the disparities from the original pure land doctrines,endowing the pure land conviction in the work with rich color of worldly interests.展开更多
Oleanolic acid (OA) exhibited good pharmacological activities in the clinical treatment of hypoglycemia, immune regulation, acute jaundice and chronic toxic hepatitis. However, the oral delivery of OA is greatly limit...Oleanolic acid (OA) exhibited good pharmacological activities in the clinical treatment of hypoglycemia, immune regulation, acute jaundice and chronic toxic hepatitis. However, the oral delivery of OA is greatly limited by its inferior water solubility and poor intestinal mucosa permeability. Herein, we developed a novel polymeric nanoparticle (NP) delivery system based on vitamin E modified aliphatic polycarbonate (mPEG-PCC-VE) to facilitate oral absorption of OA. OA encapsulated mPEG-PCC-VE NPs (OA/mPEG-PCC-VE NPs) showed uniform particle size of about 170 nm with high drug loading capability (8.9%). Furthermore, the polymeric mPEG-PCC-VE NPs, with good colloidal stability and pH-sensitive drug release characteristics, significantly enhanced the in vitro dissolution of OA in the alkaline medium. The in situ single pass intestinal perfusion (SPIP) studies performed on rats demonstrated that the OA/m PEG-PCC-VE NPs showed significantly improved permeability in the whole intestinal tract when compared to OA solution, especially for duodenum and colon. As a result, the in vivo pharmacokinetics study indicated that the bioavailability of OA/m PEG-PCC-VE NPs showed 1.5-fold higher than commercially available OA tablets. These results suggest that mPEGPCC-VE NPs are a promising platform to facilitate the oral delivery of OA.展开更多
Community residents play an important role in the development of rural tourism. Taking the interest demands of stakeholders and non-cooperative game process as main line,the conflict of interest between community resi...Community residents play an important role in the development of rural tourism. Taking the interest demands of stakeholders and non-cooperative game process as main line,the conflict of interest between community residents and tourists and between community residents themselves as guidance,it built an interest relation model for community participating in rural tourism. Besides,it elaborated non-cooperative relation and their interest pattern for stakeholders of rural tourism,and discussed behavior interaction process and results of core stakeholders of rural tourism. Finally,it came up with pertinent recommendations for harmonious and healthy development of rural tourism.展开更多
To look through innovation management in small project-based firms, such as software engineering companies, which are service firms that conduct projects for their clients, capability maturity model integration (CMMI...To look through innovation management in small project-based firms, such as software engineering companies, which are service firms that conduct projects for their clients, capability maturity model integration (CMMI) is introduced. It is a process improvement approach that provides organizations with the essential elements of effective processes. Taking ABC Software Company as an example, the performances before and after the introduction of CMMI in the firm were compared. The results indicated that after two years of application, the productivity increased 92%, and the ability of detecting errors improved 26.45% ; while the rate of faults and the cost of software development dropped 12.45% and 77.55%, respectively. To conclude, small project-based firms benefit a lot if they take CMMI into their process of innovation management, particularly for those R&D firms, since the implementation of CMMI leads them to a promising future with higher efficiency and better effects.展开更多
The 0206 Earthquake, occurring on February 6, 2016, caused the collapse of the Yongkang-Wei Guan building in Tainan City, leading to the death of 115 people and trapping about three hundred people waiting for the resc...The 0206 Earthquake, occurring on February 6, 2016, caused the collapse of the Yongkang-Wei Guan building in Tainan City, leading to the death of 115 people and trapping about three hundred people waiting for the rescue. No sooner had the earthquake occurred, the Tainan City Government Fire Department immediately set up a disaster response center and command center to dispatch the rescue team in time, which is appreciated by the citizens. A year after the earthquake, a survey is conducted, aiming to collect and reflect civic opinions and satisfaction on the rescue during 0206 earthquake. Therefore, the purposes of this study are as follows: 1) This survey will facilitate the Tainan city government to device future marketing strategies and continue to promote new policy. 2) This survey will guide Tainan City Government Fire Department on how to enhance the disaster rescue. 3) This survey will serve as the reference for other cities, intending to develop similar fire-fighting tactical strategies.展开更多
The effect of heating temperature and thermal-cold recycle times on microstructure and hardness of a W-Cr-Mn-Mo-V Ferro-based hardfacing layer was studied.The results show the surfacing layer has good high-temperature...The effect of heating temperature and thermal-cold recycle times on microstructure and hardness of a W-Cr-Mn-Mo-V Ferro-based hardfacing layer was studied.The results show the surfacing layer has good high-temperature stability and ability to resist quench heat and heat softening.After thermal-cold recycle at 560°C??18°C for 120 times,the hardness of the hardfacing layer is HRC 57.5,its microstructure is mainly tempered martensite and a small amount of retained austenite,when thermal-cold recycled at 680°C??18°C for 120 times,the hardness of the hardfacing layer is HRC 44.5,martensite in the hardfacing layer has almost decomposed.展开更多
文摘In the era of rapid development of informatization,the informatization construction of national higher vocational colleges has been in the period of application deepening.China's education system is deepening to the development of mass education,and higher vocational colleges'adult continuing education plays a great role for the realization of education popularization.With the continuous expansion of continuing education enrollment scale,the diversified development of education mode,the higher complexity of continuing education management and the increase of management workload,the traditional management method has gradually become unapplicable.Higher vocational colleges can greatly improve the management level by promoting the informatization of education management according to their own professional or regional advantages.
文摘Based on the needs of personnel training in the sustainable development of enterprises, this paper has researched that cultivating high-quality technical personnel of enterprises is the requirements of the sustainable development of enterprises. Universities in the continuing educational process should establish the basic principles of cultivating high-quality technical personnel of enterprises, and developing continuing education in universities and actively exploring the training mode of high-quality technical personnel of enterprises are proposed.
文摘Confucius's "No Child Left Behind" education ideology which was put forward two thousand years ago reflected the importance of education for educators and the simple pursuit of educational equity at that time. Education Fair is the current composition content of China's basic education dream. Practicing "No Child Left Behind" education is the cornerstone to achieve China's fair education dream. Making implementing continuing education in order to achieve "No Child Left Behind" equitable education as a research issue, based on analyzing the status and problems of educational equity issues under the perspective of NCLB, the author explored the realistic way through multi-channel and diverse continuing education to achieve "No Child Left Behind "equitable education.
文摘Recently, the scale of higher education for adults is expanding and at the same time, the teaching quality is declining, which has been increasingly focused on. In order to improve the teaching quality, at first, it is necessary to build up a set of integrative and complete teaching quality evaluation system, which is composed of class, course major and college respectively from the aspects of learning and teaching because of the particularity of the students and teaching modes of higher education for adults.
文摘From data published by the Hong Kong SAR(HKSAR)government in their two sole fisheries surveys of 2006 and 2016/2017,the current authors produced regional maps using spatial interpolation to more accurately describe and estimate the geographic coverage of changes in fishing production in Hong Kong waters since the ground trawl ban of 2012 December 31st.These suggest the fishing industry has adapted to smaller craft,and that fishing production increased in several areas in the period after the ground trawl ban came into effect.In addition,the maps enable a smoother assessment to be made of the geospatial changes in fishing production which have occurred since the ground trawl ban and suggest a‘workaround’by fishermen.In particular,small fishing craft known as sampans are able to take advantage by being more suitable vessels for areas such as narrower or shallower bays.Marine plastics pollution is also a proxy indicator of these activities,as evidenced by discarded fishing gear that includes plastic nets,floats,and other fishing boat equipment.
基金Supported by National Natural Science Foundation of China,No.82260412.
文摘BACKGROUND Hepatic cystic and alveolar echinococcosis coinfections,particularly with concurrent abscesses and sinus tract formation,are extremely rare.This article presents a case of a patient diagnosed with this unique presentation,discussing the typical imaging manifestations of both echinococcosis types and detailing the diagnosis and surgical treatment experience thereof.CASE SUMMARY A 39-year-old Tibetan woman presented with concurrent hepatic cystic and alveolar echinococcosis,accompanied by abdominal wall abscesses and sinus tract formation.Initial conventional imaging examinations suggested only hepatic cystic echinococcosis,but intraoperative and postoperative pathological examination revealed the coinfection.Following radical resection of the lesions,the patient’s condition improved,and she was discharged soon thereafter.Subsequent outpatient follow-ups confirmed no recurrence of the hydatid lesion and normal surgical wound healing.Though mixed hepatic cystic and alveolar echinococcosis with abdominal wall abscesses and sinus tract formations are rare,the general treatment approach remains consistent with that of simpler infections of alveolar echinococcosis.CONCLUSION Lesions involving the abdominal wall and sinus tract formation,may require radical resection.Long-term prognosis includes albendazole and follow-up examinations.
基金supported by the Natural Science Foundation of China(61673169,11301127,11701176,11626101,11601485)。
文摘In the article,we prove that the double inequalities Gp[λ1a+(1-λ1)b,λ1 b+(1-λ1)a]A1-p(a,b)<T[A(a,b),G(a,b)]<Gp[μ1 a+(1-μ1)b,μ1b+(1-μ1)a]A1-p(a,b),Cs[λ^(2) a+(1-λ2)b,λ2 b+(1-λ2)a]A1-s(a,b)<T[A(a,b),Q(a,b)]<Cs[μ2 a+(1-μ2)b,μ2 b+(1-μ2)a]A1-p(a,b)hold for all a,b>0 with a≠b if and only ifλ1≤1/2-(1-(2/π)2/p)1/2/2,μ1≥1/2-(2p)1/2/(4 p),λ2≤1/2+(2(3/(2 s)(E(21/2/2)/π)1/s)-1)1/2/2 andμ2≥1/2+s1/2/(4 s)ifλ1,μ1∈(0,1/2),λ2,μ2∈(1/2,1),p≥1 and s≥1/2,where G(a,b)=(ab)1/2,A(a,b)=(a+b)/2,T(a,b)=∫0π/2(a2 cos2 t+b2 sin2)1/2 tdt/π,Q(a,b)=((a2+b2)/2)1/2,C(a,b)=(a2+b2)/(a+b)and E(r)=∫0π/2(1-r^(2) sin^(2))1/2 tdt.
基金Supported by University Continuing Education Teaching Reform Project(2019jxjj67)Provincial quality engineering project of"Traditional Chinese Medicine Technique and Skilled Master Studio"of Anhui Provincial Department of Education in 2020(2020dsgzs23)+3 种基金Key Natural Science Research Project of Higher Learning Institutions in Anhui Province in 2018(KJ2018A0884)Key Natural Science Research Projects of Colleges and Universities in Anhui Province in 2020(KJ2020A1014)Key Project of 2020 Applied Technology Research and Collaborative Innovation Center of Bozhou Vocational and Technical College(BZZX202001)Key Research Project of Bozhou Vocational and Technical College in 2020(BYK2002)。
文摘Serum pharmacochemistry of traditional Chinese medicine has become a more accurate and rapidly developing reasonable way to analyze the effective material basis of traditional Chinese medicine in recent years. Through this method, we can select very complex Chinese medicine components and clarify the effective substances consistent with the main functions, and then separate and purify effective ingredients in traditional Chinese medicine, so as to explain the material basis of the drug effect and prove the rationality and principle of action of Chinese medicine compounds. It can show the multi-component and multi-target characteristic of traditional Chinese medicine, and after analyzing the migrating components of serum, we can explore the direct effective substances that act on the patient’s body, so as to accelerate and accurately complete the in-depth study of the effective substances of Chinese medicine.
基金University Continuing Education Teaching Reform Project(2019jxjj67)Natural Science Research Projects of Colleges and Universities in Anhui Province(KJ2017A772)。
文摘According to the different types of liver damage,there should also be different Chinese medicine and dose for different degrees of treatment and protection.This paper studies the Chinese medicine treatment of different types of liver injury,and is expected to provide a reference for the further application of Chinese medicine in liver injury.
基金This study was supported by the National Natural Science Foundation of China(30901909).
文摘Objective:To determine the effect of an immunosuppressive active component (periploside A) isolated from the stem bark of Periplocae Cortex (Periploca sepium Bge.),a Chinese medicinal herb used in the treatment of rheumatoid arthritis for centuries in China,on positive selection of thymocytes in vitro.Methods:Female C57BL/6 mice at 6 weeks of age were housed in specific pathogen-free conditions.Double-positive thymocytes from C57BL/6 mice were induced into positive selection in vitro with or without periploside A treatment.Cell viability and expression of CD69,CD4,and CD8 were analyzed by flow cytometry.Results:Flow cytometric examination of thymocyte populations revealed that the percentage of CD8+ single-positive thymocytes was decreased by periploside A upon differentiation induced by an anti-CD3 antibody.However,the percentage of CD4+ single-positive thymocytes was decreased by periploside A upon differentiation induced by phorbol 12-myristate 13-acetate/ionomycin.Expression of CD69 plays a major role in prohibiting differentiation of thymocytes.Treatment with periploside A decreased CD69 expression in thymocytes.Conclusion:These results demonstrate that periploside A influences positive selection of thymocytes in vitro.
文摘The aim of this paper is to seek the numerical solution of a class of variable order fractional integral-differential equation in terms of Bernstein polynomials.The fractional derivative is described in the Caputo sense.Four kinds of operational matrixes of Bernstein polynomials are introduced and are utilized to reduce the initial equation to the solution of algebraic equations after dispersing the variable.By solving the algebraic equations,the numerical solutions are acquired.The method in general is easy to implement and yields good results.Numerical examples are provided to demonstrate the validity and applicability of the method.
文摘The pure land conviction was quite prevalent in the Peace Time when The Tale of Genji was published.Murasaki Shikibuestablished the pure land conviction in The Tale of Genjialong with the skeleton which expands from the decline of aristocracy to the consciousness of the mappōand the eschatology,and then to the abominate toward impure land as well as the desire for pure land.Besides,she assimilated the doctrines and aesthetics from the pure land classics as well as inaugurated the disparities from the original pure land doctrines,endowing the pure land conviction in the work with rich color of worldly interests.
基金financial support the National Natural Science Foundation of China,No.81373336,81473164
文摘Oleanolic acid (OA) exhibited good pharmacological activities in the clinical treatment of hypoglycemia, immune regulation, acute jaundice and chronic toxic hepatitis. However, the oral delivery of OA is greatly limited by its inferior water solubility and poor intestinal mucosa permeability. Herein, we developed a novel polymeric nanoparticle (NP) delivery system based on vitamin E modified aliphatic polycarbonate (mPEG-PCC-VE) to facilitate oral absorption of OA. OA encapsulated mPEG-PCC-VE NPs (OA/mPEG-PCC-VE NPs) showed uniform particle size of about 170 nm with high drug loading capability (8.9%). Furthermore, the polymeric mPEG-PCC-VE NPs, with good colloidal stability and pH-sensitive drug release characteristics, significantly enhanced the in vitro dissolution of OA in the alkaline medium. The in situ single pass intestinal perfusion (SPIP) studies performed on rats demonstrated that the OA/m PEG-PCC-VE NPs showed significantly improved permeability in the whole intestinal tract when compared to OA solution, especially for duodenum and colon. As a result, the in vivo pharmacokinetics study indicated that the bioavailability of OA/m PEG-PCC-VE NPs showed 1.5-fold higher than commercially available OA tablets. These results suggest that mPEGPCC-VE NPs are a promising platform to facilitate the oral delivery of OA.
文摘Community residents play an important role in the development of rural tourism. Taking the interest demands of stakeholders and non-cooperative game process as main line,the conflict of interest between community residents and tourists and between community residents themselves as guidance,it built an interest relation model for community participating in rural tourism. Besides,it elaborated non-cooperative relation and their interest pattern for stakeholders of rural tourism,and discussed behavior interaction process and results of core stakeholders of rural tourism. Finally,it came up with pertinent recommendations for harmonious and healthy development of rural tourism.
文摘To look through innovation management in small project-based firms, such as software engineering companies, which are service firms that conduct projects for their clients, capability maturity model integration (CMMI) is introduced. It is a process improvement approach that provides organizations with the essential elements of effective processes. Taking ABC Software Company as an example, the performances before and after the introduction of CMMI in the firm were compared. The results indicated that after two years of application, the productivity increased 92%, and the ability of detecting errors improved 26.45% ; while the rate of faults and the cost of software development dropped 12.45% and 77.55%, respectively. To conclude, small project-based firms benefit a lot if they take CMMI into their process of innovation management, particularly for those R&D firms, since the implementation of CMMI leads them to a promising future with higher efficiency and better effects.
文摘The 0206 Earthquake, occurring on February 6, 2016, caused the collapse of the Yongkang-Wei Guan building in Tainan City, leading to the death of 115 people and trapping about three hundred people waiting for the rescue. No sooner had the earthquake occurred, the Tainan City Government Fire Department immediately set up a disaster response center and command center to dispatch the rescue team in time, which is appreciated by the citizens. A year after the earthquake, a survey is conducted, aiming to collect and reflect civic opinions and satisfaction on the rescue during 0206 earthquake. Therefore, the purposes of this study are as follows: 1) This survey will facilitate the Tainan city government to device future marketing strategies and continue to promote new policy. 2) This survey will guide Tainan City Government Fire Department on how to enhance the disaster rescue. 3) This survey will serve as the reference for other cities, intending to develop similar fire-fighting tactical strategies.
文摘The effect of heating temperature and thermal-cold recycle times on microstructure and hardness of a W-Cr-Mn-Mo-V Ferro-based hardfacing layer was studied.The results show the surfacing layer has good high-temperature stability and ability to resist quench heat and heat softening.After thermal-cold recycle at 560°C??18°C for 120 times,the hardness of the hardfacing layer is HRC 57.5,its microstructure is mainly tempered martensite and a small amount of retained austenite,when thermal-cold recycled at 680°C??18°C for 120 times,the hardness of the hardfacing layer is HRC 44.5,martensite in the hardfacing layer has almost decomposed.