The lack of knowledge concerning modelling existing buildings leads to significant variability in fragility curves for single or grouped existing buildings. This study aims to investigate the uncertainties of fragilit...The lack of knowledge concerning modelling existing buildings leads to significant variability in fragility curves for single or grouped existing buildings. This study aims to investigate the uncertainties of fragility curves, with special consideration of the single-building sigma. Experimental data and simplified models are applied to the BRD tower in Bucharest, Romania, a RC building with permanent instrumentation. A three-step methodology is applied： （1） adjustment of a linear MDOF model for experimental modal analysis using a Timoshenko beam model and based on Anderson＇s criteria, （2） computation of the structure＇s response to a large set of accelerograms simulated by SIMQKE software, considering twelve ground motion parameters as intensity measurements （IM）, and （3） construction of the fragility curves by comparing numerical interstory drift with the threshold criteria provided by the Hazus methodology for the slight damage state. By introducing experimental data into the model, uncertainty is reduced to 0.02 considering Sd ） as seismic intensity IM and uncertainty related to the model is assessed at 0.03. These values must be compared with the total uncertainty value of around 0.7 provided by the Hazus methodology.展开更多
Multipotent mesenchymal stromal cells(MSC),have the potential to differentiate into cells of the mesenchymal lineage and have non-progenitor functions including immunomodulation.The demonstration that MSCs are perivas...Multipotent mesenchymal stromal cells(MSC),have the potential to differentiate into cells of the mesenchymal lineage and have non-progenitor functions including immunomodulation.The demonstration that MSCs are perivascular cells found in almost all adult tissues raises fascinating perspectives on their role in tissue maintenance and repair.However,some controversies about the physiological role of the perivascular MSCs residing outside the bone marrow and on their therapeutic potential in regenerative medicine exist.In brain,perivascular MSCs like pericytes and adventitial cells,could constitute another stem cell population distinct to the neural stem cell pool.The demonstration of the neuronal potential of MSCs requires stringent criteria including morphological changes,the demonstration of neural biomarkers expression,electrophysiological recordings,and the absence of cell fusion.The recent finding that brain cancer stem cells can transdifferentiate into pericytes is another facet of the plasticity of these cells.It suggests that the perversion of the stem cell potential of pericytes might play an even unsuspected role in cancer formation and tumor progression.展开更多
Passive seismic techniques have revolutionarised seismology, leading for example to increased resolution in surface wave tomography, to the possibility to monitor changes in the propagation medium, and to many new pro...Passive seismic techniques have revolutionarised seismology, leading for example to increased resolution in surface wave tomography, to the possibility to monitor changes in the propagation medium, and to many new processing strategies in seismic exploration. Here we review applications of the new techniques to a very particular dataset, namely data from the Apollo 17 lunar network. The special conditions of the lunar noise environment are investigated, illustrating the interplay between the properties of the noise and the ability to reconstruct Green＇s functions. With a dispersion analysis of reconstructed Rayleigh waves new information about the shallow shear velocity structure of the Moon are obtained. Passive image interferometry is used to study the effect of temperature changes in the subsurface on the seismic velocities providing direct observation of a dynamic process in the lunar environment. These applications highlight the potential of passive techniques for terrestrial and planetary seismology.展开更多
Geomaterials are known to be non-associated materials. Granular soils therefore exhibit a variety of failure modes, with diffuse or localized kinematical patterns. In fact, the notion of failure itself can be confusin...Geomaterials are known to be non-associated materials. Granular soils therefore exhibit a variety of failure modes, with diffuse or localized kinematical patterns. In fact, the notion of failure itself can be confusing with regard to granular soils, because it is not associated with an obvious phenomenology. In this study, we built a proper framework, using the second-order work theory, to describe some failure modes in geomaterials based on energy conservation. The occurrence of failure is defined by an abrupt increase in kinetic energy. The increase in kinetic energy from an equilibrium state, under incremental loading, is shown to be equal to the difference between the external second-order work,involving the external loading parameters, and the internal second-order work, involving the constitutive properties of the material. When a stress limit state is reached, a certain stress component passes through a maximum value and then may decrease. Under such a condition, if a certain additional external loading is applied, the system fails, sharply increasing the strain rate. The internal stress is no longer able to balance the external stress, leading to a dynamic response of the specimen. As an illustration, the theoretical framework was applied to the well-known undrained triaxial test for loose soils. The influence of the loading control mode was clearly highlighted. It is shown that the plastic limit theory appears to be a particular case of this more general second-order work theory. When the plastic limit condition is met, the internal second-order work is nil. A class of incremental external loadings causes the kinetic energy to increase dramatically, leading to the sudden collapse of the specimen, as observed in laboratory.展开更多
The decadal variability of rainfall and vegetation over West Africa have been studied over the last three decades, 1981-1990, 1991-2000 and 2001-2010 denoted as 1980s, 1990s and 2000s, respectively. Climate Research U...The decadal variability of rainfall and vegetation over West Africa have been studied over the last three decades, 1981-1990, 1991-2000 and 2001-2010 denoted as 1980s, 1990s and 2000s, respectively. Climate Research Unit (CRU) monthly precipitation and Normalized Difference Vegetation Index (NDVI) from the National Oceanic and Atmosphere Administration (NOAA), all covering the period 1981-2010 have been used. This study aimed to assess the changes in the land surface condition and the spatio-temporal distribution of rainfall over West Africa region. The relationship between rainfall and vegetation indices over this region was determined using Pearson’s correlation. Also, the decadal comparison between rainfall and NDVI over the region was based on the significant t-test and the Pearson’s correlation. Results showed that significant return to wet conditions is observed between decade 1980s and decade 1990s over West Africa, and also during decade 2000s with the exception of central Benin and the western Nigeria. Meanwhile, a regreening of the central Sahel and Sudano-Sahel regions is noted. From 1990s to 2000s, this regreening belt is located in the South and the coastal areas: the Guinea Coast, Sudano-Guinea and western Sahel regions. A northward displacement of this re-greening belt is also detected. Thus, a linear relationship occurs between rainfall and NDVI in the Sudanian savannah region, but it is not the case in the rest of West Africa. This may suggest that the re-growth of vegetation in the Sudanian savannah region may be linked to rainfall supplies. Therefore, re-greening over Sahel region in 1990s is related to rainfall recovery. However, this re-greening was not sustained in the decade 2000s due to a slight decrease in rainfall.展开更多
The spatiotemporal evolution patterns of complete Coulomb stress changes caused by 1988 Ms7.6 earthquake in Lancang-Gengma, Yunnan, are calculated and studied. And the triggering problems of Ms7.2 Gengma shock occurri...The spatiotemporal evolution patterns of complete Coulomb stress changes caused by 1988 Ms7.6 earthquake in Lancang-Gengma, Yunnan, are calculated and studied. And the triggering problems of Ms7.2 Gengma shock occurring 13 minutes after the main shock and of Ms5.0―6.9 aftershocks within 24 days after the main shock are discussed. The results show that the spatial distribution patterns of complete Coulomb stress changes of the Ms7.6 main shock are strongly asymmetric. The areas of positive dynamic and static Coulomb stress are both coincident well with the strong aftershocks' loca-tions. The Ms7.2 Gengma shock and most of strong aftershocks are subjected to the triggering effect of dynamic and static Coulomb stresses induced by the Ms7.6 Lancang earthquake.展开更多
The critical properties of the mixed manganite La0.67–x Y x Ba0.23Ca0.1Mn O3 with x=0.10 and x=0.15 around the paramagnetic（PM）-ferromagnetic（FM） phase transition were investigated through various techniques. The...The critical properties of the mixed manganite La0.67–x Y x Ba0.23Ca0.1Mn O3 with x=0.10 and x=0.15 around the paramagnetic（PM）-ferromagnetic（FM） phase transition were investigated through various techniques. These involved modified Arrott plots, Kouvel-Fisher method and Widom scaling relation. Magnetic data, analyzed in the critical region, using the above methods, yielded the critical exponents for（x=0.10） La0.57Y0.10Ba0.23Ca0.1Mn O3（β=0.312±0.002 and γ=1.147±0.003 at T C=299.23±0.05 K）. Moreover, the estimated critical exponents of（x=0.15） La0.52Y0.15Ba0.23Ca0.1Mn O3 were β=0.286±0.004 and γ=0.943±0.002 at T C=289.53±0.06 K. The critical exponents＇ values were close to the theoretical values of 3D-Ising model and tricritical mean-field model. These results suggested that the present composition should be close to a tricritical point in the La0.67–x Y x Ba0.23Ca0.1Mn O3 phase diagram. Expressing the field dependence as ΔS M∝H n allowed us to establish a relationship between the exponent n and the critical exponents of the material and to propose a phenomenological universal curve for the field dependence of ΔS M.展开更多
At ISOLDE (CERN),an on-line test bench is dedicated to charge breeding experiments with a 14GHz Phoenix ion source,for the investigation of the 1+→n+ scenario at next generation ISOL-type facilities.This year,various...At ISOLDE (CERN),an on-line test bench is dedicated to charge breeding experiments with a 14GHz Phoenix ion source,for the investigation of the 1+→n+ scenario at next generation ISOL-type facilities.This year,various technical developments have been undertaken for intensifying the tests of the on- line performances of the booster with a high diversity of stable and radioactive ion beams.This contribution will present an overview of the latest developments,the current challenges,and some perspectives for the future use of the Phoenix booster for physics experiments at ISOLDE.展开更多
We discuss model-independent constraints on spin observables in exclusive and inclusive reactions, with special attention to the case of photoproduction.
基金the ANR National Research Agency as Part of Its RiskNat Program(URBASIS project)under Grant No.ANR-09-RISK-009the Rh ne-Alpes Regional Council(Programme Vulnerabilitédes Ouvrages aux Risques)and the Joseph Fourier Université(Grenoble 1)
文摘The lack of knowledge concerning modelling existing buildings leads to significant variability in fragility curves for single or grouped existing buildings. This study aims to investigate the uncertainties of fragility curves, with special consideration of the single-building sigma. Experimental data and simplified models are applied to the BRD tower in Bucharest, Romania, a RC building with permanent instrumentation. A three-step methodology is applied： （1） adjustment of a linear MDOF model for experimental modal analysis using a Timoshenko beam model and based on Anderson＇s criteria, （2） computation of the structure＇s response to a large set of accelerograms simulated by SIMQKE software, considering twelve ground motion parameters as intensity measurements （IM）, and （3） construction of the fragility curves by comparing numerical interstory drift with the threshold criteria provided by the Hazus methodology for the slight damage state. By introducing experimental data into the model, uncertainty is reduced to 0.02 considering Sd ） as seismic intensity IM and uncertainty related to the model is assessed at 0.03. These values must be compared with the total uncertainty value of around 0.7 provided by the Hazus methodology.
基金Supported by INSERM and the Ligue contre le Cancer Isère-Rhne Alpes
文摘Multipotent mesenchymal stromal cells(MSC),have the potential to differentiate into cells of the mesenchymal lineage and have non-progenitor functions including immunomodulation.The demonstration that MSCs are perivascular cells found in almost all adult tissues raises fascinating perspectives on their role in tissue maintenance and repair.However,some controversies about the physiological role of the perivascular MSCs residing outside the bone marrow and on their therapeutic potential in regenerative medicine exist.In brain,perivascular MSCs like pericytes and adventitial cells,could constitute another stem cell population distinct to the neural stem cell pool.The demonstration of the neuronal potential of MSCs requires stringent criteria including morphological changes,the demonstration of neural biomarkers expression,electrophysiological recordings,and the absence of cell fusion.The recent finding that brain cancer stem cells can transdifferentiate into pericytes is another facet of the plasticity of these cells.It suggests that the perversion of the stem cell potential of pericytes might play an even unsuspected role in cancer formation and tumor progression.
文摘Passive seismic techniques have revolutionarised seismology, leading for example to increased resolution in surface wave tomography, to the possibility to monitor changes in the propagation medium, and to many new processing strategies in seismic exploration. Here we review applications of the new techniques to a very particular dataset, namely data from the Apollo 17 lunar network. The special conditions of the lunar noise environment are investigated, illustrating the interplay between the properties of the noise and the ability to reconstruct Green＇s functions. With a dispersion analysis of reconstructed Rayleigh waves new information about the shallow shear velocity structure of the Moon are obtained. Passive image interferometry is used to study the effect of temperature changes in the subsurface on the seismic velocities providing direct observation of a dynamic process in the lunar environment. These applications highlight the potential of passive techniques for terrestrial and planetary seismology.
基金the French Research Network Me Ge (Multiscale and Multiphysics Couplings in Geo-environmental Mechanics GDR CNRS 3176/2340, 2008e2015) for having supported this work
文摘Geomaterials are known to be non-associated materials. Granular soils therefore exhibit a variety of failure modes, with diffuse or localized kinematical patterns. In fact, the notion of failure itself can be confusing with regard to granular soils, because it is not associated with an obvious phenomenology. In this study, we built a proper framework, using the second-order work theory, to describe some failure modes in geomaterials based on energy conservation. The occurrence of failure is defined by an abrupt increase in kinetic energy. The increase in kinetic energy from an equilibrium state, under incremental loading, is shown to be equal to the difference between the external second-order work,involving the external loading parameters, and the internal second-order work, involving the constitutive properties of the material. When a stress limit state is reached, a certain stress component passes through a maximum value and then may decrease. Under such a condition, if a certain additional external loading is applied, the system fails, sharply increasing the strain rate. The internal stress is no longer able to balance the external stress, leading to a dynamic response of the specimen. As an illustration, the theoretical framework was applied to the well-known undrained triaxial test for loose soils. The influence of the loading control mode was clearly highlighted. It is shown that the plastic limit theory appears to be a particular case of this more general second-order work theory. When the plastic limit condition is met, the internal second-order work is nil. A class of incremental external loadings causes the kinetic energy to increase dramatically, leading to the sudden collapse of the specimen, as observed in laboratory.
文摘The decadal variability of rainfall and vegetation over West Africa have been studied over the last three decades, 1981-1990, 1991-2000 and 2001-2010 denoted as 1980s, 1990s and 2000s, respectively. Climate Research Unit (CRU) monthly precipitation and Normalized Difference Vegetation Index (NDVI) from the National Oceanic and Atmosphere Administration (NOAA), all covering the period 1981-2010 have been used. This study aimed to assess the changes in the land surface condition and the spatio-temporal distribution of rainfall over West Africa region. The relationship between rainfall and vegetation indices over this region was determined using Pearson’s correlation. Also, the decadal comparison between rainfall and NDVI over the region was based on the significant t-test and the Pearson’s correlation. Results showed that significant return to wet conditions is observed between decade 1980s and decade 1990s over West Africa, and also during decade 2000s with the exception of central Benin and the western Nigeria. Meanwhile, a regreening of the central Sahel and Sudano-Sahel regions is noted. From 1990s to 2000s, this regreening belt is located in the South and the coastal areas: the Guinea Coast, Sudano-Guinea and western Sahel regions. A northward displacement of this re-greening belt is also detected. Thus, a linear relationship occurs between rainfall and NDVI in the Sudanian savannah region, but it is not the case in the rest of West Africa. This may suggest that the re-growth of vegetation in the Sudanian savannah region may be linked to rainfall supplies. Therefore, re-greening over Sahel region in 1990s is related to rainfall recovery. However, this re-greening was not sustained in the decade 2000s due to a slight decrease in rainfall.
基金Supported by the National Natural Science Foundation of China (Grant No. 40364001)the Key Lab. Open Foundation for Earth and Space Environment and Geodesy of the Ministry of Education of China (Grant No. 03-04-07)
文摘The spatiotemporal evolution patterns of complete Coulomb stress changes caused by 1988 Ms7.6 earthquake in Lancang-Gengma, Yunnan, are calculated and studied. And the triggering problems of Ms7.2 Gengma shock occurring 13 minutes after the main shock and of Ms5.0―6.9 aftershocks within 24 days after the main shock are discussed. The results show that the spatial distribution patterns of complete Coulomb stress changes of the Ms7.6 main shock are strongly asymmetric. The areas of positive dynamic and static Coulomb stress are both coincident well with the strong aftershocks' loca-tions. The Ms7.2 Gengma shock and most of strong aftershocks are subjected to the triggering effect of dynamic and static Coulomb stresses induced by the Ms7.6 Lancang earthquake.
文摘The critical properties of the mixed manganite La0.67–x Y x Ba0.23Ca0.1Mn O3 with x=0.10 and x=0.15 around the paramagnetic（PM）-ferromagnetic（FM） phase transition were investigated through various techniques. These involved modified Arrott plots, Kouvel-Fisher method and Widom scaling relation. Magnetic data, analyzed in the critical region, using the above methods, yielded the critical exponents for（x=0.10） La0.57Y0.10Ba0.23Ca0.1Mn O3（β=0.312±0.002 and γ=1.147±0.003 at T C=299.23±0.05 K）. Moreover, the estimated critical exponents of（x=0.15） La0.52Y0.15Ba0.23Ca0.1Mn O3 were β=0.286±0.004 and γ=0.943±0.002 at T C=289.53±0.06 K. The critical exponents＇ values were close to the theoretical values of 3D-Ising model and tricritical mean-field model. These results suggested that the present composition should be close to a tricritical point in the La0.67–x Y x Ba0.23Ca0.1Mn O3 phase diagram. Expressing the field dependence as ΔS M∝H n allowed us to establish a relationship between the exponent n and the critical exponents of the material and to propose a phenomenological universal curve for the field dependence of ΔS M.
基金Supported by EU Within the EURONS and EURISOL DS under Respective Contract Numbers RII3-CT-2004-506065 and RIDS 515768
文摘At ISOLDE (CERN),an on-line test bench is dedicated to charge breeding experiments with a 14GHz Phoenix ion source,for the investigation of the 1+→n+ scenario at next generation ISOL-type facilities.This year,various technical developments have been undertaken for intensifying the tests of the on- line performances of the booster with a high diversity of stable and radioactive ion beams.This contribution will present an overview of the latest developments,the current challenges,and some perspectives for the future use of the Phoenix booster for physics experiments at ISOLDE.
文摘We discuss model-independent constraints on spin observables in exclusive and inclusive reactions, with special attention to the case of photoproduction.
