Gallium trichloride-catalyzed conjugate addition of indole and pyrrole to α,β-unsaturated ketones in aqueous media

Michael addition of indole and pyrrole to a variety of α, β-unsaturated ketones was efficiently promoted by a catalytic amount of GaCl3 in aqueous media to afford the corresponding products in good to excellent yields.

Decondensation behavior of DNA chains induced by multivalent cations at high salt concentrations:Molecular dynamics simulations and experiments

Using molecular dynamics simulations and atomic force microscopy （AFM）, we study the decondensation process of DNA chains induced by multivalent cations at high salt concentrations in the presence of short cationic chains in solutions. The typical simulation conformations of DNA chains with varying salt concentrations for multivalent cations imply that the concentration of salt cations and the valence of multivalent cations have a strong influence on the process of DNA decondensation. The DNA chains are condensed in the absence of salt or at low salt concentrations, and the compacted conformations of DNA chains become loose when a number of cations and anions are added into the solution. It is explicitly demonstrated that cations can overcompensate the bare charge of the DNA chains and weaken the attraction interactions between the DNA chains and short cationic chains at high salt concentrations. The condensation-decondensation transi- tions of DNA are also experimentally observed in mixing spermidine with X-phage DNA at different concentrations of NaCl/MgCl2 solutions.

Multinanoparticle Translocations in Phospholipid Membranes:Translocation Modes and Dynamic Processes

Multinanoparticles interacting with the phospholipid membranes in solution were studied by dissipative particle dynamics simulation.The selected nanoparticles have spherical or cylindrical shapes,and they have various initial velocities in the dynamical processes.Several translocation modes are defined according to their characteristics in the dynamical processes,in which the phase diagrams are constructed based on the interaction strengths between the particles and membranes and the initial velocities of particles.Furthermore,several parameters,such as the system energy and radius of gyration,are investigated in the dynamical processes for the various translocation modes.Results elucidate the effects of multiparticles interacting with the membranes in the biological processes.

Research on the road landscape evaluation system with the emphasis on the landscape ecology

As the idea of the sustainable development wins support among the people, people have already realized that not only should the road have the transportation function, but we also should consider the rationality of the road construction fi＇om the multiple angles of the landscape ecology, and the visual art and so on. From the point of view of the landscape ecology, combined with the characteristics of the landscape ecology and the overall targets and requirements of the evaluation, this article constructs a three-tier system of indicators, uses the fuzzy comprehensive evaluation model based on the analytic hierarchy process to evaluate the road landscape, and makes an empirical analysis with the evaluation of the road landscape fi＇om the Luoshi Road to the East Lake Road in the Second Loop of Wuhan City as an example.

Morphologies of Core-Shell-Cylinder-Forming ABC Star Triblock Copolymers in Nanopores

The self-assembly behavior of ABC star triblock copolymers can lead to a large number of nanostructures. Indeed, many new and interesting structures have already been discovered and proven to be hotspot in soft matter physics research. In this work, we introduce different phase diagrams of core-shell-cylinder-forming ABC star triblock copolymers under different conditions, including in-bulk and pore geometries with different sizes. The relation between the pore size geometries and their corresponding structures are also revealed. The different properties of the surface potential field that significantly affect the self-assembly process of ABC star triblock copolymers are investigated as well.

Surface-field-induced effects on morphologies of lamella-forming diblock copolymers in nanorod arrays

The surface-induced effect on the morphologies of lamella-forming diblock copolymers in nanorod arrays is studied by using the self-consistent field theory. In the simulation study, a rich variety of novel morphologies are observed by variations in the strength of the surface field for the diblock copolymers. Different surface-field-induced effects are examined for the diblock copolymers in the arrays with distinct preferential surfaces. It is observed that the majority-block preferential surfaces have more obvious induced effects than those of minority-block preferential surfaces. The strong surface fields exhibit different behaviours from those observed in the weak surface fields, by which the morphologies possess cylindrical symmetries. Results from this research deepen the knowledge of surface-induced effects in a confinement system, which may aid the fabrication of polymer-based na^omaterials.

NBS-Promoted Sulfenylation of Sulfinates with Disulfides Leading to Unsymmetrical or Symmetrical Thiosulfonates

A highly practical method to access unsymmetrical and symmetrical thiosulfonates in moderate to excellent yields has been developed through NBS-promoted sulfenylation of sulfinates with disulfides. The present process enables the use of two RS in RSSR and shows broad functional group tolerance, which represents an atom-economical and practical procedure for the synthesis of thiosulfonates. A plausible mechanism for the role of NBS as a promoter for the cleavage of disulfides generating N-（organothio）succinimide that then undergos facile sulenylation with sulfinates is proposed.

Surface-induced Morphologies of ABC Star Triblock Copolymer in Spherical Cavities

The morphologies and phase diagrams exhibited by symmetric ABC star triblock copolymer nanoparticles are investigated on the basis of real-space self-consistent field theory. The ABC star triblock copolymers were chosen to be tiling-forming with fixed polymer parameter and the spherical boundaries were modeled using the masking technique. We first study a number of examples where the ABC triblock copolymers confined in spherical cavities with neutral surface. Then, two types of spherical cavity distinct preferential surfaces are considered, including both A-block attractive and repulsive preferential surfaces. We aim at the effects due to various spherical cavity diameters and the degree of interactions between the polymer and the spherical surface. A variety of morphologies, such as ring-like structures, concentric sphere, and irregular cylinder, were identified in phase diagrams. The results show that both the degree of interactions and spherical diameters can influence the formation of morphologies so that ring-like structures and other novel structures could be obtained.

A deep-learning method for evaluating shaft resistance of the cast-in-site pile on reclaimed ground using field data

This study proposes a deep learning-based approach for shaft resistance evaluation of cast-in-site piles on reclaimed ground,independent of theoretical hypotheses and engineering experience.A series of field tests was first performed to investigate the characteristics of the shaft resistance of cast-in-site piles on reclaimed ground.Then,an intelligent approach based on the long short term memory deep-learning technique was proposed to calculate the shaft resistance of the cast-in-site pile.The proposed method allows accurate estimation of the shaft resistance of cast-in-site piles,not only under the ultimate load but also under the working load.Comparisons with empirical methods confirmed the effectiveness of the proposed method for the shaft resistance estimation of cast-in-site piles on reclaimed ground in offshore areas.

An approach to the Paal–Knorr pyrroles synthesis in the presence of β-cyclodextrin in aqueous media

An efficient and facile method for the synthesis of N-substituted pyrroles in moderate to good yields by the Paal-Knorr reaction of β-diketones with amines in the presence of β-cyclodextrin in aqueous media has been developed. Moreover, this process tolerated diamines （e.g., para-, metaor orthophenylenediamine） to construct bis-pyrrole or mono-pyrrole derivates.β-Cyclodextrin can be recovered easily after the reactions and reused without evident loss in activity.