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TC21合金在不同温度下进行连续多步置氢处理时的显微组织及室温力学性能
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作者 袁宝国 钱德国 +2 位作者 张小雪 陈强 汤爱闯 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2024年第5期1520-1532,共13页
利用OM、XRD、TEM以及压缩试验等方法研究TC21钛合金经不同温度连续多步置氢处理后的显微组织及室温力学性能。结果表明:当氢处理温度超过1073 K时,α相的尺寸明显降低,β相成为主要相。随着氢处理温度的升高,δ氢化物的含量呈先增加后... 利用OM、XRD、TEM以及压缩试验等方法研究TC21钛合金经不同温度连续多步置氢处理后的显微组织及室温力学性能。结果表明:当氢处理温度超过1073 K时,α相的尺寸明显降低,β相成为主要相。随着氢处理温度的升高,δ氢化物的含量呈先增加后逐渐降低的趋势。当氢处理温度超过1073 K时,TC21钛合金在室温压缩变形过程中出现应变软化现象,且该现象随氢处理温度的升高而越来越显著。随着氢处理温度的升高,TC21钛合金的极限变形率呈先降低后增加的趋势。当氢处理温度为1123 K时,TC21钛合金的极限变形率比原始合金增加67.51%。 展开更多
关键词 TC21合金 连续多步置氢处理 室温力学性能 压力-组成等温线
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Surviving winter on the Qinghai-Xizang Plateau:Extensive reversible protein phosphorylation plays a dominant role in regulating hypometabolism in hibernating Nanorana parkeri
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作者 Yong-Gang Niu Deng-Bang Wei +6 位作者 Xue-Jing Zhang Ti-Sen Xu Xiang-Yong Li Hai-Ying Zhang Zhi-Fang An Kenneth B.Storey qiang chen 《Zoological Research》 SCIE CSCD 2024年第1期1-12,共12页
Changes in protein abundance and reversible protein phosphorylation(RPP)play important roles in regulating hypometabolism but have never been documented in overwintering frogs at high altitudes.To test the hypothesis ... Changes in protein abundance and reversible protein phosphorylation(RPP)play important roles in regulating hypometabolism but have never been documented in overwintering frogs at high altitudes.To test the hypothesis that protein abundance and phosphorylation change in response to winter hibernation,we conducted a comprehensive and quantitative proteomic and phosphoproteomic analysis of the liver of the Xizang plateau frog,Nanorana parkeri,living on the Qinghai-Xizang Plateau.In total,5170 proteins and 5695 phosphorylation sites in 1938 proteins were quantified.Based on proteomic analysis,674 differentially expressed proteins(438 up-regulated,236 down-regulated)were screened in hibernating N.parkeri versus summer individuals.Functional enrichment analysis revealed that higher expressed proteins in winter were significantly enriched in immune-related signaling pathways,whereas lower expressed proteins were mainly involved in metabolic processes.A total of 4251 modified sites(4147 up-regulated,104 down-regulated)belonging to 1638 phosphoproteins(1555 up-regulated,83 down-regulated)were significantly changed in the liver.During hibernation,RPP regulated a diverse array of proteins involved in multiple functions,including metabolic enzymatic activity,ion transport,protein turnover,signal transduction,and alternative splicing.These changes contribute to enhancing protection,suppressing energy-consuming processes,and inducing metabolic depression.Moreover,the activities of phosphofructokinase,glutamate dehydrogenase,and ATPase were all significantly lower in winter compared to summer.In conclusion,our results support the hypothesis and demonstrate the importance of RPP as a regulatory mechanism when animals transition into a hypometabolic state. 展开更多
关键词 Nanorana parkeri PROTEOMIC Phosphoproteomic HIBERNATION Reversible protein phosphorylation Metabolism
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I-DCGAN and TOPSIS-IFP:A simulation generation model for radiographic flaw detection images in light alloy castings and an algorithm for quality evaluation of generated images
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作者 Ming-jun Hou Hao Dong +7 位作者 Xiao-yuan Ji Wen-bing Zou Xiang-sheng Xia Meng Li Ya-jun Yin Bao-hui Li qiang chen Jian-xin Zhou 《China Foundry》 SCIE EI CAS CSCD 2024年第3期239-247,共9页
The intelligent detection technology driven by X-ray images and deep learning represents the forefront of advanced techniques and development trends in flaw detection and automated evaluation of light alloy castings.H... The intelligent detection technology driven by X-ray images and deep learning represents the forefront of advanced techniques and development trends in flaw detection and automated evaluation of light alloy castings.However,the efficacy of deep learning models hinges upon a substantial abundance of flaw samples.The existing research on X-ray image augmentation for flaw detection suffers from shortcomings such as poor diversity of flaw samples and low reliability of quality evaluation.To this end,a novel approach was put forward,which involves the creation of the Interpolation-Deep Convolutional Generative Adversarial Network(I-DCGAN)for flaw detection image generation and a comprehensive evaluation algorithm named TOPSIS-IFP.I-DCGAN enables the generation of high-resolution,diverse simulated images with multiple appearances,achieving an improvement in sample diversity and quality while maintaining a relatively lower computational complexity.TOPSIS-IFP facilitates multi-dimensional quality evaluation,including aspects such as diversity,authenticity,image distribution difference,and image distortion degree.The results indicate that the X-ray radiographic images of magnesium and aluminum alloy castings achieve optimal performance when trained up to the 800th and 600th epochs,respectively.The TOPSIS-IFP value reaches 78.7%and 73.8%similarity to the ideal solution,respectively.Compared to single index evaluation,the TOPSIS-IFP algorithm achieves higher-quality simulated images at the optimal training epoch.This approach successfully mitigates the issue of unreliable quality associated with single index evaluation.The image generation and comprehensive quality evaluation method developed in this paper provides a novel approach for image augmentation in flaw recognition,holding significant importance for enhancing the robustness of subsequent flaw recognition networks. 展开更多
关键词 light alloy casting flaw detection image generator DISCRIMINATOR comprehensive evaluation index
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Dynamically changing antineutrophil cytoplasmic antibodies in granulomatosis with polyangiitis:A case report
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作者 Yan Zhang Qiao-Ding Dai +3 位作者 Ji-An Wang Li-Ping Xu qiang chen Yang-Zi Jin 《World Journal of Clinical Cases》 SCIE 2024年第16期2881-2886,共6页
BACKGROUND Granulomatosis with polyangiitis(GPA)is one of the most prevalent forms of the antineutrophil cytoplasmic antibody(ANCA)-associated vasculitis.GPA is characterized histologically by necrotizing granulomatou... BACKGROUND Granulomatosis with polyangiitis(GPA)is one of the most prevalent forms of the antineutrophil cytoplasmic antibody(ANCA)-associated vasculitis.GPA is characterized histologically by necrotizing granulomatous inflammation in addition to vasculitis.The diagnosis of GPA depends on clinical presentation,serological evidence of a positive ANCA,and/or histological evidence of necrotizing vasculitis or granulomatous destructive parenchymal inflammation.Cytoplasmic ANCA(c-ANCA)is positive in 65%-75% of GPA patients,accompanied by proteinase 3(PR3),the main target antigen of c-ANCA,another 5% of GPA patients had negative ANCA.CASE SUMMARY The patient,a 52-year-old male,presented with unexplained nasal congestion,tinnitus,and hearing loss.After a duration of 4 months experiencing these symptoms,the patient subsequently developed fever and headache.The imaging examination revealed the presence of bilateral auricular mastoiditis and partial paranasal sinusitis,and the ANCA results were negative.The anti-infective therapy proved to be ineffective,but the patient's symptoms and fever were quickly relieved after 1 wk of treatment with methylprednisolone 40 mg once a day.However,after continuous use of methylprednisolone tablets for 3 months,the patient experienced a recurrence of fever accompanied by right-sided migraine,positive c-ANCA and PR3,and increased total protein in cerebrospinal fluid.The and cyclophosphamide 0.8 g monthly,the patient experienced alleviation of fever and headache.Additionally,the ANCA levels became negative and there has been no recurrence.CONCLUSION For GPA patients with negative ANCA,there is a potential for early missed diagnosis.The integration of histopathological results and multidisciplinary communication plays a crucial role in facilitating ANCA-negative GPA. 展开更多
关键词 Anti-neutrophil cytoplasmic antibodies Granulomatosis with polyangiitis Antineutrophil cytoplasmic antibodyassociated vasculitis Immunosuppressive therapy Case report
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WE43合金在不同应力状态下的本构关系及断裂行为表征 被引量:1
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作者 武鹏飞 张冲 +2 位作者 娄燕山 陈强 宁海青 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2023年第2期438-453,共16页
研究WE43合金在不同应力状态下的塑性和断裂行为。设计拉伸、压缩及剪切试样,并进行力学实验。采用数字图像相关技术对测试过程进行记录和处理。实验结果表明:WE43合金具有低的拉压非对称性,其断裂机制属于韧性断裂。基于Drucker屈服函... 研究WE43合金在不同应力状态下的塑性和断裂行为。设计拉伸、压缩及剪切试样,并进行力学实验。采用数字图像相关技术对测试过程进行记录和处理。实验结果表明:WE43合金具有低的拉压非对称性,其断裂机制属于韧性断裂。基于Drucker屈服函数,采用不同的硬化规律模拟单轴拉伸和压缩下的塑性变形行为。通过数值模拟得到应力状态和断裂应变。采用Brozzo、Oh、Ko-Huh和DF2016准则对韧性断裂行为进行数值预测,并与实验结果进行对比。结果表明:采用Swift-Voce硬化定律和Drucker屈服函数能合理模拟塑性变形。DF2016断裂准则能准确预测合金在各种应力状态下的断裂行为。 展开更多
关键词 稀土镁合金 塑性变形行为 应力状态效应 本构模型 韧性断裂预测
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AlLi相对Mg−Li合金热压缩变形行为和动态再结晶的影响 被引量:1
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作者 甘翼 胡励 +4 位作者 时来鑫 陈强 李明骜 向林 周涛 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2023年第5期1373-1384,共12页
采用等温热压缩实验研究含有AlLi相的Mg−5Li−3Al−2Zn(LAZ532)合金的热变形行为;变形温度和应变速率范围分别为473~623 K和0.001~1 s^(−1)。LAZ532合金热变形过程中AlLi相能够阻碍位错运动,从而显著提高合金的峰值应力值。为精确预测LAZ... 采用等温热压缩实验研究含有AlLi相的Mg−5Li−3Al−2Zn(LAZ532)合金的热变形行为;变形温度和应变速率范围分别为473~623 K和0.001~1 s^(−1)。LAZ532合金热变形过程中AlLi相能够阻碍位错运动,从而显著提高合金的峰值应力值。为精确预测LAZ532合金的热变形行为,构建相应的应变补偿Arrhenius本构模型,预测结果与实验结果吻合良好。基于Murty准则,建立相应的热加工图,合理的加工区域在538~623 K和0.001~0.01 s^(−1)范围内。在高应变速率变形条件下,AlLi相不利于LAZ532合金在热压缩过程中的流动稳定性和动态再结晶。此外,变形温度会改变LAZ532合金的动态再结晶形核机制。 展开更多
关键词 Mg−Li合金 AlLi相 本构模型 加工图 动态再结晶
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Low-pressure-RF plasma modification of UiO-66 and its application in methylene blue adsorption 被引量:2
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作者 周甜 杨斗豪 +4 位作者 王一骏 程久珊 陈强 刘博文 刘忠伟 《Plasma Science and Technology》 SCIE EI CAS CSCD 2023年第8期122-129,共8页
Defect engineering of metal-organic frameworks has attracted increasing attention in recent years for potential applications in gas storage and catalysis.In this study,defective UiO-66 is obtained by Ar and H_(2)plasm... Defect engineering of metal-organic frameworks has attracted increasing attention in recent years for potential applications in gas storage and catalysis.In this study,defective UiO-66 is obtained by Ar and H_(2)plasma treatments.Compared with the pristine UiO-66,a new aperture with a size of~4 nm appears for a sample with the plasma modification,indicating the formation of mesopores within UiO-66 framework.Characterization results demonstrate that the pore volume,surface area and the number of Lewis and Br?nsted acid sites can be easily tuned by varying the discharge parameters.The adsorption performance of UiO-66 is evaluated for the adsorption of methyl blue.In comparison to the pristine UiO-66 and the sample with H_(2)plasma treatment,the Ar plasma modified sample shows excellent adsorption activity due to the suitable pore size and volume.Equilibrium adsorption capacity as high as 40.6 mg·g^(-1)is achieved for the UiO-66(Ar)sample. 展开更多
关键词 Ar plasma UiO-66 DEFECTS metal-organic frameworks
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Effect of neutral pressure on the blue core in Ar helicon plasma under an inhomogeneous magnetic field 被引量:1
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作者 王陈文 刘洋 +4 位作者 孙萌 张天亮 谢俊发 陈强 张海宝 《Plasma Science and Technology》 SCIE EI CAS CSCD 2023年第4期93-100,共8页
The effect of neutral pressure on the blue core in Ar helicon plasma under an inhomogeneous magnetic field was investigated in this work.The neutral pressure was set to 0.08 Pa,0.36 Pa,and 0.68 Pa.A Nikon camera,inten... The effect of neutral pressure on the blue core in Ar helicon plasma under an inhomogeneous magnetic field was investigated in this work.The neutral pressure was set to 0.08 Pa,0.36 Pa,and 0.68 Pa.A Nikon camera,intensified charge-coupled device(ICCD),optical emission spectrometer(OES),and Langmuir probe were used to diagnose the blue core in helicon plasma.Helicon plasma discharges experienced density jumps from the E mode,H mode to W mode before power just rose to 200 W.The plasma density increased and maintained a central peak with the increase of neutral pressure.However,the brightness of the blue core gradually decreased.It is demonstrated that the relative intensity of Ar II spectral lines and the ionization rate in the central area were reduced.Radial electron temperature profiles were flattened and became hollow as neutral pressure increased.It is demonstrated that increasing the neutral pressure weakened the central heating efficiency dominated by the helicon wave and strengthened the edge heating efficiency governed by the TG wave and skin effect.Therefore,the present experiment successfully reveals how the neutral pressure affects the heating mechanism of helicon plasma in an inhomogeneous magnetic field. 展开更多
关键词 helicon plasma blue core neutral pressure heating mechanism edge heating
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High-order field theory and a weak Euler–Lagrange–Barut equation for classical relativistic particle-field systems
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作者 范培锋 陈强 +1 位作者 肖建元 于治 《Plasma Science and Technology》 SCIE EI CAS CSCD 2023年第11期42-54,共13页
In both quantum and classical field systems,conservation laws such as the conservation of energy and momentum are widely regarded as fundamental properties.A broadly accepted approach to deriving conservation laws is ... In both quantum and classical field systems,conservation laws such as the conservation of energy and momentum are widely regarded as fundamental properties.A broadly accepted approach to deriving conservation laws is built using Noether's method.However,this procedure is still unclear for relativistic particle-field systems where particles are regarded as classical world lines.In the present study,we establish a general manifestly covariant or geometric field theory for classical relativistic particle-field systems.In contrast to quantum systems,where particles are viewed as quantum fields,classical relativistic particle-field systems present specific challenges.These challenges arise from two sides.The first comes from the mass-shell constraint.To deal with the mass-shell constraint,the Euler–Lagrange–Barut(ELB)equation is used to determine the particle's world lines in the four-dimensional(4D)Minkowski space.Besides,the infinitesimal criterion,which is a differential equation in formal field theory,is reconstructed by an integro-differential form.The other difficulty is that fields and particles depend on heterogeneous manifolds.To overcome this challenge,we propose using a weak version of the ELB equation that allows us to connect local conservation laws and continuous symmetries in classical relativistic particle-field systems.By applying a weak ELB equation to classical relativistic particle-field systems,we can systematically derive local conservation laws by examining the underlying symmetries of the system.Our proposed approach provides a new perspective on understanding conservation laws in classical relativistic particle-field systems. 展开更多
关键词 high-order field theory weak Euler-Lagrange-Barut equation infinitesimal criterion of symmetric condition Noether's theorem geometric conservation laws
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Influence of bimodal non-basal texture on microstructure characteristics,texture evolution and deformation mechanisms of AZ31 magnesium alloy sheet rolled at liquid-nitrogen temperature
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作者 Shouzuo Zhang Li Hu +7 位作者 Yutao Ruan Tao Zhou qiang chen Yang Zhong Laixin Shi Mingao Li Mingbo Yang Shuyong Jiang 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2023年第7期2600-2609,共10页
Cryogenic rolling experiments have been conducted on the AZ31 magnesium(Mg)alloy sheet with bimodal non-basal texture,which is fabricated via the newly developed equal channel angular rolling and continuous bending pr... Cryogenic rolling experiments have been conducted on the AZ31 magnesium(Mg)alloy sheet with bimodal non-basal texture,which is fabricated via the newly developed equal channel angular rolling and continuous bending process with subsequent annealing(ECAR-CB-A)process.Results demonstrate that this sheet shows no edge cracks until the accumulated thickness reduction reaches about 18.5%,which is about 105.6%larger than that of the sheet with traditional basal texture.Characterization experiments including optical microstructure(OM),X-ray diffractometer(XRD),and electron backscatter diffraction(EBSD)measurements are then performed to explore the microstructure characteristics,texture evolution and deformation mechanisms during cryogenic rolling.Experimental observations confirm the occurrence of abundant{10–12}extension twins(ETs),twin-twin interactions among{10–12}ET variants and{10–12}-{10–12}double twins(DTs).The twinning behaviors as for{10–12}ETs are responsible for the concentration of c-axes of grains towards normal direction(ND)and the formation of transverse direction(TD)-component texture at the beginning of cryogenic rolling.The twinning behaviors with respect to{10–12}-{10–12}DTs are responsible for the disappearance of TD-component texture at the later stage of cryogenic rolling.The involved deformation mechanisms can be summarized as follows:Firstly{10–12}ETs dominate the plastic deformation.Subsequently,dislocation slip,especially basal<a>slip,starts to sustain more plastic strain,while{10–12}ETs occur more frequently and enlarge continuously,resulting in the formation of twin-twin interaction among{10–12}ET variants.With the increasing rolling passes,{10–12}-{10–12}DTs incorporate in the plastic deformation and dislocation slip serves as the major one to sustain plastic strain.The activities of basal<a>slip,{10–12}ETs and{10–12}-{10–12}DTs benefit in accommodating the plastic strain in sheet thickness,which contributes to the improved rolling formability in AZ31 Mg alloy sheet with bimodal non-basal texture during cryogenic rolling. 展开更多
关键词 AZ31 Mg alloy Bimodal non-basal texture Cryogenic rolling Microstructure evolution Deformation mechanism
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Simultaneous measurements of refractive index and temperature based on a no-core fiber coated with Ag and PDMS films
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作者 李宇昕 陈海良 +5 位作者 张赢月 陈强 武彪 樊晓亚 刘英超 马明建 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第5期471-477,共7页
A compact surface plasmon resonance(SPR) fiber optic sensor, being utilized to simultaneously measure refractive index(RI) and temperature, is proposed and experimentally demonstrated in this paper. One part of a no-c... A compact surface plasmon resonance(SPR) fiber optic sensor, being utilized to simultaneously measure refractive index(RI) and temperature, is proposed and experimentally demonstrated in this paper. One part of a no-core fiber(NCF)was coated with a silver(Ag) film, and the other part was coated with a silver/polydimethylsiloxane(Ag/PDMS) composite film to stimulate the SPR effect. Due to the two heterogeneous films, two dips appeared in the transmission spectrum and were used to achieve the dual-parameter measurements. The experimental results showed that the RI sensitivity reached 2121.43 nm/RIU and 0 nm/RIU, while the temperature sensitivity reached-0.32 nm/℃ and-2.21 nm/℃ for the two dips,respectively. Based on the obtained transfer matrix, the measurements of RI and temperature could be demodulated. This designed sensor showed the merits of simple structure, easy to implement, and high sensitivity, demonstrating application prospects in dual-parameter monitoring. 展开更多
关键词 no-core fiber surface plasmon resonance temperature sensor
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Design of an optically-transparent ultra-broadband microwave absorber
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作者 高冕 陈强 +3 位作者 郑月军 袁方 孙占山 付云起 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第8期289-295,共7页
The optical window of low-observable platform needs to be compatible with ultra-broadband absorption,hence an optically-transparent absorber with ultra-broadband absorption is designed and analyzed in this paper.The t... The optical window of low-observable platform needs to be compatible with ultra-broadband absorption,hence an optically-transparent absorber with ultra-broadband absorption is designed and analyzed in this paper.The transparent materials indium-tin-oxide(ITO)film and polymethylmethacrylate(PMMA)are selected as the lossy layer and the supporting dielectric layer,respectively.The optically-transparent ultra-broadband absorber(OT-UBA)is composed of three layers of ITO square patterns,three layers of PMMA dielectric and a uniform ITO plane.The ITO square patterns can realize arbitrary equivalent series of RC(resistor and capacitor)circuit,so that three layers of ITO square patterns together with the ITO plane can achieve ultra-broadband absorption based on the equivalent circuit optimization.Measured results shows that the 90%-absorption bandwidth covers 2-17 GHz while the light transmittance achieves 59.6%with a total thickness of only 12.9 mm. 展开更多
关键词 ultra-broadband absorbers optically-transparent equivalent circuit optimization
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Anisotropic characterization of different materialized scaffolds:A numerical study
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作者 Xu-Heng cheng He-Ming chen qiang chen 《Biomedical Engineering Communications》 2023年第2期35-42,共8页
Ideal bone scaffold requires its mechanical properties to match those of natural bone.This work aimed to develop an anisotropic scaffold architecture,investigate the mechanical properties and anisotropy of the scaffol... Ideal bone scaffold requires its mechanical properties to match those of natural bone.This work aimed to develop an anisotropic scaffold architecture,investigate the mechanical properties and anisotropy of the scaffold made of six biomedical materials by finite element method,and further compare them with the counterparts of natural bones for scaffold selection.The results showed that the mechanical properties of the scaffold constituent materials were positively correlated to those of the scaffolds but negatively correlated to the porosity.The modulus anisotropy was independent of materials at low porosity,and the strength anisotropy was weakly changed for high-strength materials but negatively correlated to porosity for low-strength materials.Plus,the modulus-strength chart of these materialized scaffolds against those of selected bones indicated that the mechanical match could be obtained by varying the anisotropic index.This work provided a constructing method for an anisotropic scaffold according to the structure-mechanical relationship of bone and could be helpful for scaffold design and selection to regenerate defective bones in clinical applications. 展开更多
关键词 bone scaffold mechanical property ANISOTROPY modulus-strength chart finite element method
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补肾益精方对外周血BMSCs在干性ARMD小鼠中视网膜分化及CNTF表达的影响 被引量:2
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作者 许凯 唐由之 +5 位作者 梁丽娜 张晶 侯乐 梁洁 陈强 马群英 《国际眼科杂志》 CAS 北大核心 2021年第4期597-603,共7页
目的:观察补肾益精方对外周血移植骨髓间充质干细胞(BMSCs)在视网膜分化及睫状神经营养因子(CNTF)表达的影响,探讨补肾益精方治疗干性年龄相关性黄斑变性(ARMD)的作用机制。方法:将24只C57BL/6小鼠以碘酸钠(NaIO3)尾静脉注射的方法建立... 目的:观察补肾益精方对外周血移植骨髓间充质干细胞(BMSCs)在视网膜分化及睫状神经营养因子(CNTF)表达的影响,探讨补肾益精方治疗干性年龄相关性黄斑变性(ARMD)的作用机制。方法:将24只C57BL/6小鼠以碘酸钠(NaIO3)尾静脉注射的方法建立干性ARMD模型。造模后第1d,尾静脉注射3×106个绿色荧光蛋白标记的骨髓间充质干细胞(GFP-BMSCs),按随机数字表法分为蒸馏水组(12只,给予蒸馏水灌胃)及补肾益精方组(12只,给予补肾益精方灌胃)。另选12只健康C57BL/6小鼠常规饲养作为正常组。治疗14d时,采用免疫荧光染色观察GFP-BMSCs在视网膜的分化情况;免疫荧光染色及实时荧光定量PCR检测CNTF在视网膜中的表达情况。结果:免疫荧光染色显示补肾益精方组胶质纤维酸性蛋白(GFAP)及GFP双染细胞阳性率高于蒸馏水组(P<0.01);两组视网膜色素上皮细胞特异蛋白65(RPE65)及GFP双染细胞阳性率无差异(P>0.05);两组均未见视紫红质(Rhodopsin)与GFP双染阳性细胞。免疫荧光染色及实时荧光定量PCR显示补肾益精方组CNTF的表达高于蒸馏水组(P<0.05)。结论:补肾益精方能够促进外周血BMSCs在视网膜分化为胶质细胞,并促进CNTF的表达,这可能是补肾益精方治疗干性ARMD的作用机制之一。 展开更多
关键词 补肾益精方 骨髓间充质干细胞 细胞分化 睫状神经营养因子 干性年龄相关性黄斑变性
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Design and Availability Research of a Flammable and Explosive Volatiles Monitoring and Early Warning System (FEVMEW) for the Bus Crowded Places
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作者 Cen Yu Weibin Guo +2 位作者 Ruyi Li qiang chen Tianping Xu 《Journal of Computer and Communications》 2020年第12期83-90,共8页
<div style="text-align:justify;"> In order to reduce the arson or accidental fire losses, we developed a gas sensitive detector used for the rapid detection and early warning of flammables in crowded p... <div style="text-align:justify;"> In order to reduce the arson or accidental fire losses, we developed a gas sensitive detector used for the rapid detection and early warning of flammables in crowded places such as buses. A MEMS (Micro-Electro-Mechanical System) based thin film semiconductor was fabricated as the gas sensor. To obtain the target gas selective response, the surface of the sensitive film was modified with highly active metal catalytic nano-particles. Thus the anti-interference ability was improved and the false alarm rate was effectively reduced. Furthermore, the modular embedded system for information acquisition and transmission was developed. Supported by the Airflow Precision control system (APs), the rapid warning of volatile gas of flammable substances was realized. Experiments showed that RAs has satisfied selectivity to volatiles of usual flammable liquid, such as the output voltage reaches 3 V (0 - 3.3 V). With simulation about the actual installation state in bus, MWs sounds an alarm at 2 minutes after splashing 50 mL 92# petrol to the floor. For the last two years, FEVMEW has been integrated into more than 4000 buses in Hefei. This design has been proved feasible according to the actual operation. </div> 展开更多
关键词 Flammable and Explosive Volatiles Monitoring and Early Warning Bus Crowded Places Gas Sensitive MEMS Chip Airflow Regulating
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部分再结晶对NiFeCoCrMn高熵合金显微组织和拉伸性能的影响 被引量:7
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作者 杜辉 蔡嘉洪 +4 位作者 王亚松 姚俊卿 陈强 崔宇 刘鑫旺 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2022年第3期947-956,共10页
为了调控NiFeCoCrMn高熵合金强度和塑性之间的平衡关系,采用传统的热力学加工技术(冷轧和再结晶),通过不同的再结晶退火工艺得到不同程度的位错强化,并对具有不同再结晶比例的合金进行拉伸性能测试。随着再结晶比例的增加,即应变硬化程... 为了调控NiFeCoCrMn高熵合金强度和塑性之间的平衡关系,采用传统的热力学加工技术(冷轧和再结晶),通过不同的再结晶退火工艺得到不同程度的位错强化,并对具有不同再结晶比例的合金进行拉伸性能测试。随着再结晶比例的增加,即应变硬化程度的下降,合金的均匀伸长率和加工硬化率显著提高,但屈服强度和抗拉强度降低。尤其在650℃分别退火10 min和15 min时,获得的再结晶比例分别为37%和74%,相应的屈服强度为1003 MPa和742 MPa,均匀伸长率为4%和24%。强化主要来源于含高密度位错的未再结晶组织,而塑性则是由无应变的再结晶晶粒产生。 展开更多
关键词 高熵合金 部分再结晶 显微组织 拉伸性能 强化机制
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聚α-甲基苯乙烯空心微球的开裂机理 被引量:1
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作者 潘大伟 杨璨 +4 位作者 李洁 陈强 李波 黄卫星 刘梅芳 《高分子材料科学与工程》 EI CAS CSCD 北大核心 2019年第4期47-51,共5页
干燥过程是制备高表面质量聚α-甲基苯乙烯(PAMS)空心微球的关键过程之一。文中通过实验研究了不同热处理温度(55℃、75℃、95℃)和不同干燥温度(室温、45℃、65℃、85℃、100℃)对PAMS空心微球干燥过程的影响。实验结果表明,采用不同... 干燥过程是制备高表面质量聚α-甲基苯乙烯(PAMS)空心微球的关键过程之一。文中通过实验研究了不同热处理温度(55℃、75℃、95℃)和不同干燥温度(室温、45℃、65℃、85℃、100℃)对PAMS空心微球干燥过程的影响。实验结果表明,采用不同温度对PAMS空心微球进行热处理后,具有严重初始微缺陷的空心微球所占百分比没有显著差异。因为最高热处理温度(95℃)远远低于PAMS的玻璃化转变温度(≈180℃)而不能使PAMS分子链段运动以消除残余内应力。随着干燥温度的升高,干燥后的空心微球表面出现裂纹的比例相应增加。干燥温度的升高将会导致空心微球球壳所受应力不断增大。而球壳所受应力是其产生裂纹的主要原因之一。 展开更多
关键词 乳液 表面 聚α-甲基苯乙烯空心微球 乙醇交换 裂纹
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可控表面磷原子修饰提升超细W_(2)C纳米颗粒电解水析氢反应性能 被引量:1
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作者 张祥勇 刘添滢 +9 位作者 郭挺 韩雪莹 木宗云 陈强 蒋江民 闫婧 袁加仁 王德志 吴壮志 寇宗魁 《Chinese Journal of Catalysis》 SCIE EI CAS CSCD 2021年第10期1798-1807,共10页
研究高活性和稳定性的非贵金属基析氢催化剂对解决当前能源危机和环境污染问题具有重要意义.碳化鹄具有与贵金属Pt类似的d带电子结构,因而成为一类新兴的非贵金属析氢催化剂,受到广泛关注.磷掺杂是提高催化剂析氢活性的有效方法之一,然... 研究高活性和稳定性的非贵金属基析氢催化剂对解决当前能源危机和环境污染问题具有重要意义.碳化鹄具有与贵金属Pt类似的d带电子结构,因而成为一类新兴的非贵金属析氢催化剂,受到广泛关注.磷掺杂是提高催化剂析氢活性的有效方法之一,然而目前最常见的构筑磷掺杂方法是使用多金属氧酸盐(POMs,如H3PW_(12)O_(40)),其固定的W/P原子比导致W_(2)C中的掺杂浓度难以调控,并且磷掺杂主要是进入碳载体而不是碳化物本身,从而导致无法明确杂原子对其电催化析氢活性的贡献.本文采用植酸(PA)为磷源设计合成了可控磷掺杂W_(2)C纳米颗粒,并探讨了催化剂组分、杂原子掺杂位置与析氢性能之间的关系.深入研究了磷掺杂碳化钨(WCP)的化学结构和析氢活性.与原始的W_(2)C催化剂相比,WCP具有更高的本征活性、更快的电子转移速率和更多的活性位数量,并且在酸性和碱性条件下均表现出较好的析氢性能.特别是过电位为-200 mV时,WCP催化剂的本征活性在酸性和碱性条件下分别为0.07和0.56H_(2)s^(-1),高出纯W_(2)C(0.01和0.05 H_(2)s^(-1))数倍.同时,在电流密度为-10mA cm^(-2)时,优化后的WCP催化剂在酸性和碱性条件下的析氢过电位分别降低了96和88 mV.XPS及EDS元素分析结果表明,随磷源添加量增加,磷掺杂从碳化钨表面逐渐向内部扩散,进一步说明磷取代位置与析氢活性之间的构效关系,高浓度的表面磷取代可以加速质子捕获过程,从而显著提高其析氢活性,而过量的内部磷取代会破坏W_(2)C结构,降低电子转移速率,从而导致析氢性能下降.利用密度泛函理论计算深入研究了WCP具有较好析氢性能的原因,与内部磷取代相比,表面磷取代会使碳化钩表现出更合适的氢吸附自由能,并且更加有效地降低了氢释放势垒,从而优化了析氢反应动力学.综上,本文为元素掺杂工艺提供了新的思路,同时研究了表面异质原子对析氢活性的关键作用,为该类催化材料的构效关系研究提供了新思路. 展开更多
关键词 碳化钨 掺杂 表面修饰 析氢反应 电催化剂
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输尿管导管及锥形导丝在输尿管中上段碎石术中的临床应用 被引量:2
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作者 种丽强 陈艳杰 +2 位作者 陈强 张楠楠 杨彬 《中国内镜杂志》 2020年第11期56-60,共5页
目的探讨输尿管导管及锥形导丝在输尿管中上段碎石术中的临床应用效果。方法选取于该院就诊的输尿管中上段结石患者150例,随机分为对照组(锥形导丝组)和观察组(输尿管导管组),每组各75例。比较两组患者的手术时间、住院天数、总费用、... 目的探讨输尿管导管及锥形导丝在输尿管中上段碎石术中的临床应用效果。方法选取于该院就诊的输尿管中上段结石患者150例,随机分为对照组(锥形导丝组)和观察组(输尿管导管组),每组各75例。比较两组患者的手术时间、住院天数、总费用、术中结石逃逸情况、术后血尿、发热、肾绞痛等并发症发生情况和术后1个月结石排净率。结果两组患者手术时间和治疗费用比较,差异均有统计学意义;住院天数、术中结石逃逸情况、术后并发症发生率和术后1个月结石排净率比较,差异均无统计学意义。结论应用锥形导丝及输尿管导管治疗输尿管中上段结石,治疗效果明确且并发症少。输尿管导管较锥形导丝手术时间长,但锥形导丝治疗费用相对较高。 展开更多
关键词 输尿管结石 锥形导丝 输尿管导管 钬激光碎石 临床效果
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黄羽肉鸡感染火鸡组织滴虫后血清生化指标的动态变化 被引量:1
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作者 禚振男 孔令明 +6 位作者 王子静 郭平 曲昌宝 刘丹丹 钱晨 陶建平 许金俊 《中国家禽》 北大核心 2020年第8期30-34,共5页
为了进一步从病理生理角度探究火鸡组织滴虫的致病机理,通过火鸡组织滴虫JSYZ-A株泄殖腔感染15日龄苏禽黄羽肉鸡,感染后7~31 d,每3天采集非抗凝血进行常规生化指标的测定。结果显示:火鸡组织滴虫的感染会导致感染鸡增重缓慢,谷丙转氨酶... 为了进一步从病理生理角度探究火鸡组织滴虫的致病机理,通过火鸡组织滴虫JSYZ-A株泄殖腔感染15日龄苏禽黄羽肉鸡,感染后7~31 d,每3天采集非抗凝血进行常规生化指标的测定。结果显示:火鸡组织滴虫的感染会导致感染鸡增重缓慢,谷丙转氨酶、谷草转氨酶、谷氨酰胺转移酶、球蛋白含量不同程度上升,尿素氮、葡萄糖含量下降,甘油三酯浓度先升后降,而其他生化指标无明显异常。肝脏是火鸡组织滴虫入侵的主要靶器官,其功能受到广泛损伤,是导致鸡群发病、增重下降和死亡的主要原因。研究结果为火鸡组织滴虫致病机理的阐明和组织滴虫病的药物防治提供了一定的参考依据。 展开更多
关键词 火鸡组织滴虫 生化指标 增重
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