Capillaria hepatica(C.hepatica) is a parasitic nematode causing hepatic capillariasis in numerous mammals.Ecologic studies showed that the first hosts of C.hepatica were rodents,among which rats had relatively high in...Capillaria hepatica(C.hepatica) is a parasitic nematode causing hepatic capillariasis in numerous mammals.Ecologic studies showed that the first hosts of C.hepatica were rodents,among which rats had relatively high infection rates,which explains why C.hepatica spreads globally.Anatomical studies showed that the liver was the principal site of colonization by these parasites and physical damage tended to occur.Although C.hepatica might lead to serious liver disorders,relevant clinical reports were rare,because of the non-specific nature of clinical symptoms,leading to misdiagnosis.This review mainly focuses on the biological characteristics and epidemiology of C.hepatica in China and histopathologic changes in the liver,with expectation of gaining a better understanding of the disease and seeking more effective treatment.展开更多
AIM To compare survival and recurrence in hepatocellularcarcinoma (HCC) patients who did or did notreceive adjuvant transarterial chemoembolization(TACE).METHODS: A consecutive sample of 229 patients whounderwent...AIM To compare survival and recurrence in hepatocellularcarcinoma (HCC) patients who did or did notreceive adjuvant transarterial chemoembolization(TACE).METHODS: A consecutive sample of 229 patients whounderwent curative resection between March 2007and March 2010 in our hospital was included. Of these229 patients, 91 (39.7%) underwent curative resectionfollowed by adjuvant TACE and 138 (60.3%) underwentcurative resection alone. In order to minimize confoundsdue to baseline differences between the twopatient groups, comparisons were conducted betweenpropensity score-matched patients. Survival data andrecurrence rates were compared using the Kaplan-Meier method. Independent predictors of overall survivaland recurrence were identified using Cox proportionalhazard regression.RESULTS: Among 61 pairs of propensity scorematchedpatients, the 1-, 2-, and 3-year overall survivalrates were 95.1%, 86.7%, and 76.4% in the TACEgroup and 86.9%, 78.5%, and 73.2% in the controlgroup, respectively. At the same time, the TACE andcontrol groups also showed similar recurrence rates at1 year (13.4% vs 24.8%), 2 years (30.6% vs 32.1%),and 3 years (40.1% vs 34.0%). Multivariate Coxregression identified serum alpha-fetoprotein level ≥400 ng/mL and tumor size 〉 5 cm as independent riskfactors of mortality (P 〈 0.05).CONCLUSION: As postoperative adjuvant TACE doesnot improve overall survival or reduce recurrence inHCC patients, further study is needed to clarify itsclinical benefit.展开更多
Sulfide ion can reduce the viscosity of polymer solution. The higher the concentration of sulfide ion is, the greater the effect of viscosity on polymer is, and it directly affects oil recovery rate. Some methods for ...Sulfide ion can reduce the viscosity of polymer solution. The higher the concentration of sulfide ion is, the greater the effect of viscosity on polymer is, and it directly affects oil recovery rate. Some methods for removing sulfide were studied by adding the oxidizing substances. Each method had certain effect on removing sulfide. The addition of hydrogenperoxide in the solution makes it faster to remove sulfide than flowing air in it, although the removal of sulfide is still not complete. This removal is quick when ozone takes part in, and it will spend much time with the increased volume of solution. The extent of removing sulfide was mainly related to the oxidability of re- moved substances. The stronger the oxidability of oxidizing substances was, the better the performance for sulfide removing was. In addition, part of sulfate radical in oilfield sewage could be removed by nanofiltration membrane. Removal efficiency of sulfate radical is about 50%. The probability may be avoided that sulfate radical was reduced into sulfide by the sulfate-reducing bacteria (SRB) in sewage. This method could radically reduce the presence of the reduction of sulfur in sewage, and it can reduce the corrosion of underground oil pipeline.展开更多
The unsymmetrical bis-Schiff base manganese(III) and cobalt(II) complexes with either benzo-10-aza-crown ether pendants (MnL1Cl, MnLZCl) or morpholino pendant (MnL3Cl, CoL3) have been employed as models for hy...The unsymmetrical bis-Schiff base manganese(III) and cobalt(II) complexes with either benzo-10-aza-crown ether pendants (MnL1Cl, MnLZCl) or morpholino pendant (MnL3Cl, CoL3) have been employed as models for hy- drolase by studying the kinetics of their hydrolysis reactions with p-nitrophenyl picolinate (PNPP). A kinetic model of PNPP cleavage catalyzed by these complexes is proposed. The effects of complex structures and reaction temperature on the rate of PNPP hydrolysis have been examined. All four complexes exhibit high catalytic activity and the rate increases with pH under 25℃. The complexes of ligands containing a crown ether group exhibit higher catalytic activities than the non-crown analogues. The catalytic activity of the complexes follows the order Mn(III) 〉 Co(II) under the same ligands.展开更多
文摘Capillaria hepatica(C.hepatica) is a parasitic nematode causing hepatic capillariasis in numerous mammals.Ecologic studies showed that the first hosts of C.hepatica were rodents,among which rats had relatively high infection rates,which explains why C.hepatica spreads globally.Anatomical studies showed that the liver was the principal site of colonization by these parasites and physical damage tended to occur.Although C.hepatica might lead to serious liver disorders,relevant clinical reports were rare,because of the non-specific nature of clinical symptoms,leading to misdiagnosis.This review mainly focuses on the biological characteristics and epidemiology of C.hepatica in China and histopathologic changes in the liver,with expectation of gaining a better understanding of the disease and seeking more effective treatment.
基金Supported by Capital Special Research Project for Health Development(2014-2-4012)State Natural Research Funding,No.81372578+2 种基金National Natural Science Foundation of China,No.30970623 and No.91229120International Science and Technology Cooperation Projects,No.2010DFA31840 and No.2010DFB33720Program for New Century Excellent Talents in University,No.NCET-11-0288
文摘AIM To compare survival and recurrence in hepatocellularcarcinoma (HCC) patients who did or did notreceive adjuvant transarterial chemoembolization(TACE).METHODS: A consecutive sample of 229 patients whounderwent curative resection between March 2007and March 2010 in our hospital was included. Of these229 patients, 91 (39.7%) underwent curative resectionfollowed by adjuvant TACE and 138 (60.3%) underwentcurative resection alone. In order to minimize confoundsdue to baseline differences between the twopatient groups, comparisons were conducted betweenpropensity score-matched patients. Survival data andrecurrence rates were compared using the Kaplan-Meier method. Independent predictors of overall survivaland recurrence were identified using Cox proportionalhazard regression.RESULTS: Among 61 pairs of propensity scorematchedpatients, the 1-, 2-, and 3-year overall survivalrates were 95.1%, 86.7%, and 76.4% in the TACEgroup and 86.9%, 78.5%, and 73.2% in the controlgroup, respectively. At the same time, the TACE andcontrol groups also showed similar recurrence rates at1 year (13.4% vs 24.8%), 2 years (30.6% vs 32.1%),and 3 years (40.1% vs 34.0%). Multivariate Coxregression identified serum alpha-fetoprotein level ≥400 ng/mL and tumor size 〉 5 cm as independent riskfactors of mortality (P 〈 0.05).CONCLUSION: As postoperative adjuvant TACE doesnot improve overall survival or reduce recurrence inHCC patients, further study is needed to clarify itsclinical benefit.
基金Project supported by the Natural Science Foundation of Liaoning Province (No. 20092068), the Department of Education Key Laboratory of Liaoning Province (No. 2009S098) and the Shenyang Large Equipment Shared Services (No. 090044).
文摘Sulfide ion can reduce the viscosity of polymer solution. The higher the concentration of sulfide ion is, the greater the effect of viscosity on polymer is, and it directly affects oil recovery rate. Some methods for removing sulfide were studied by adding the oxidizing substances. Each method had certain effect on removing sulfide. The addition of hydrogenperoxide in the solution makes it faster to remove sulfide than flowing air in it, although the removal of sulfide is still not complete. This removal is quick when ozone takes part in, and it will spend much time with the increased volume of solution. The extent of removing sulfide was mainly related to the oxidability of re- moved substances. The stronger the oxidability of oxidizing substances was, the better the performance for sulfide removing was. In addition, part of sulfate radical in oilfield sewage could be removed by nanofiltration membrane. Removal efficiency of sulfate radical is about 50%. The probability may be avoided that sulfate radical was reduced into sulfide by the sulfate-reducing bacteria (SRB) in sewage. This method could radically reduce the presence of the reduction of sulfur in sewage, and it can reduce the corrosion of underground oil pipeline.
文摘The unsymmetrical bis-Schiff base manganese(III) and cobalt(II) complexes with either benzo-10-aza-crown ether pendants (MnL1Cl, MnLZCl) or morpholino pendant (MnL3Cl, CoL3) have been employed as models for hy- drolase by studying the kinetics of their hydrolysis reactions with p-nitrophenyl picolinate (PNPP). A kinetic model of PNPP cleavage catalyzed by these complexes is proposed. The effects of complex structures and reaction temperature on the rate of PNPP hydrolysis have been examined. All four complexes exhibit high catalytic activity and the rate increases with pH under 25℃. The complexes of ligands containing a crown ether group exhibit higher catalytic activities than the non-crown analogues. The catalytic activity of the complexes follows the order Mn(III) 〉 Co(II) under the same ligands.