Erectile dysfunction (ED) is a common sexual problem affecting up to one-third of men throughout their lives. According to the Massachusetts Male Aging Study (MMAS), ED affects an estimated 52% of men between the ...Erectile dysfunction (ED) is a common sexual problem affecting up to one-third of men throughout their lives. According to the Massachusetts Male Aging Study (MMAS), ED affects an estimated 52% of men between the ages of 40 and 70. With the approval of sildenafil (USA in March 1998), the first phosphodiesterase type 5 (PDE-5) inhibitor to be made available for treatment of ED, and the subsequent approval of vardenafil (USA in August 2003) and tadalafil (USA in November 2003), the PDE-5 inhibitor class of drugs has rapidly become the first-line therapy for ED of varying etiologies and severities.展开更多
文摘Erectile dysfunction (ED) is a common sexual problem affecting up to one-third of men throughout their lives. According to the Massachusetts Male Aging Study (MMAS), ED affects an estimated 52% of men between the ages of 40 and 70. With the approval of sildenafil (USA in March 1998), the first phosphodiesterase type 5 (PDE-5) inhibitor to be made available for treatment of ED, and the subsequent approval of vardenafil (USA in August 2003) and tadalafil (USA in November 2003), the PDE-5 inhibitor class of drugs has rapidly become the first-line therapy for ED of varying etiologies and severities.