A new triterpene glycoside, leucospilotaside C, along with two known saponin, was isolated from sea cucumber Holothuria leucospilota collected from the South China Sea, and its structure was elucidated as 3-0-{4′-O-s...A new triterpene glycoside, leucospilotaside C, along with two known saponin, was isolated from sea cucumber Holothuria leucospilota collected from the South China Sea, and its structure was elucidated as 3-0-{4′-O-sodiumsulfate-β′-D-xylopyranosyl}- holosta-22,25-epoxy-9-ene-3β,12α,17α-triol (1) by extensive spectroscopic analysis and chemical methods. The glycosides have the same triterpene aglycone, but differ in the oligosaccharide moieties.展开更多
A new special flavone, named desmosdumotin B, was isolated from the roots of D. dumosus and its chemical structure identified as 5-hydroxy-7-one-6,8,8-trimethylflavone by spectral analysis and X-ray.
Abstract: A new sulfated triterpene glycoside named as 17-dehydroxyholothurin A 1 was isolated from the sea cucumber Holothuria impatiens. Its structure was elucidated on the basis of spectroscopic data (2D NMR and...Abstract: A new sulfated triterpene glycoside named as 17-dehydroxyholothurin A 1 was isolated from the sea cucumber Holothuria impatiens. Its structure was elucidated on the basis of spectroscopic data (2D NMR and MS) and chemical evidence. Compound 1 showed cytotoxic activity against cancer cell lines MKN-28, MFC-7, KB, HL-60 and Hep G2 with IC50 values of 1.98, 4.53, 2.01, 4.69 and 2.80 ×10^-6 tool/L, respectively.展开更多
methyl-5-propyl-7, 12-dihydroxy chromone-12-O-β-D-glucopyranoside was isolated from the stem of Cassia siamea. The structure was elucidated by chemical and spectral evidences.
基金supported by the State Foundation for High-tech Project"863"from the Ministry of Science and Technology,China (No.2001AA624100)grant from National Natural Science Foundation of China (No.20772155).
文摘A new triterpene glycoside, leucospilotaside C, along with two known saponin, was isolated from sea cucumber Holothuria leucospilota collected from the South China Sea, and its structure was elucidated as 3-0-{4′-O-sodiumsulfate-β′-D-xylopyranosyl}- holosta-22,25-epoxy-9-ene-3β,12α,17α-triol (1) by extensive spectroscopic analysis and chemical methods. The glycosides have the same triterpene aglycone, but differ in the oligosaccharide moieties.
文摘A new special flavone, named desmosdumotin B, was isolated from the roots of D. dumosus and its chemical structure identified as 5-hydroxy-7-one-6,8,8-trimethylflavone by spectral analysis and X-ray.
文摘Abstract: A new sulfated triterpene glycoside named as 17-dehydroxyholothurin A 1 was isolated from the sea cucumber Holothuria impatiens. Its structure was elucidated on the basis of spectroscopic data (2D NMR and MS) and chemical evidence. Compound 1 showed cytotoxic activity against cancer cell lines MKN-28, MFC-7, KB, HL-60 and Hep G2 with IC50 values of 1.98, 4.53, 2.01, 4.69 and 2.80 ×10^-6 tool/L, respectively.
文摘methyl-5-propyl-7, 12-dihydroxy chromone-12-O-β-D-glucopyranoside was isolated from the stem of Cassia siamea. The structure was elucidated by chemical and spectral evidences.